Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank 薬物名（臨床試験情報から抽出） KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
1 Acalabrutinib 1件: Acalabrutinib2件: Acalabrutinib ,
Acalabrutinib maleate hydrate 💬 		1件: BTK 💬 7件: B cell receptor signaling pathway, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, NF-kappa B signaling pathway, Osteoclast differentiation, Platelet activation, Primary immunodeficiency 💬2件: 46, 61 💬
2 Atovaquone 1件: Atovaquone1件: Atovaquone 💬 --1件: 61 💬
3 Bendamustine 2件: Bendamustine; Bendamustine hydrochloride3件: Bendamustine hydrochloride ,
Bendamustine ,
Bendamustine hydrochloride hydrate 💬 		--4件: 28, 49, 51, 61 💬
4 Bortezomib 1件: Bortezomib1件: Bortezomib 💬 1件: PSMB5 💬 8件: Alzheimer disease, Amyotrophic lateral sclerosis, Huntington disease, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Prion disease, Proteasome, Spinocerebellar ataxia 💬18件: 11, 13, 26, 28, 46, 49, 51, 61, 63, 64, 66, 172, 222, 228, 256, 283, 288, 331 💬
5 Conestat alfa 6件: C1 esterase inhibitor; C1 inhibitor; C1-esterase inhibitor; Complement C1 esterase inhibitor; Conestat alfa; Recombinant human C1 inhibitor1件: Conestat alfa 💬 3件: C1R,
C1S,
KLKB1 💬 		6件: Complement and coagulation cascades, Coronavirus disease - COVID-19, Pertussis, Phagosome, Staphylococcus aureus infection, Systemic lupus erythematosus 💬2件: 61, 65 💬
6 Cyclosporine 6件: Ciclosporin; Ciclosporina; Ciclosporine; Cyclosporin; Cyclosporin A; Cyclosporine1件: Cyclosporine 💬 5件: PPP3C,
PPP3C,
PPP3C,
PPP3R,
PPP3R 💬 		33件: Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬42件: 11, 19, 20, 26, 28, 36, 40, 41, 42, 45, 46, 49, 50, 53, 54, 55, 56, 58, 60, 61, 62, 63, 64, 65, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
7 Eculizumab 1件: Eculizumab1件: Eculizumab 💬 1件: C5 💬 11件: Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Regulation of actin cytoskeleton, Staphylococcus aureus infection, Systemic lupus erythematosus 💬8件: 11, 13, 14, 61, 62, 109, 221, 222 💬
8 Efalizumab 1件: Efalizumab1件: Efalizumab 💬 1件: ITGAL 💬 12件: Cell adhesion molecules, Epstein-Barr virus infection, Human T-cell leukemia virus 1 infection, Leukocyte transendothelial migration, Malaria, Natural killer cell mediated cytotoxicity, Neutrophil extracellular trap formation, Rap1 signaling pathway, Regulation of actin cytoskeleton, Rheumatoid arthritis, Staphylococcus aureus infection, Viral myocarditis 💬9件: 11, 13, 37, 46, 53, 61, 95, 96, 221 💬
9 Erythropoietin 2件: Epoetin alfa; Erythropoietin4件: Epoetin alfa ,
Epoetin epsilon ,
Epoetin theta ,
Epoetin zeta 💬 		1件: EPOR 💬 7件: Cytokine-cytokine receptor interaction, Efferocytosis, Hematopoietic cell lineage, Hormone signaling, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer 💬11件: 2, 6, 13, 18, 22, 46, 47, 61, 70, 95, 96 💬
10 Famotidine 2件: Famotidina; Famotidine1件: Famotidine 💬 1件: HRH2 💬 4件: Calcium signaling pathway, Gastric acid secretion, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction 💬7件: 6, 46, 61, 86, 98, 145, 300 💬
11 Fludarabine 2件: Fludarabine; Fludarabine phosphate2件: Fludarabine phosphate ,
Fludarabine 💬 		1件: RRM1 💬 4件: Drug metabolism - other enzymes, Glutathione metabolism, Purine metabolism, Pyrimidine metabolism 💬25件: 11, 13, 19, 28, 34, 35, 36, 44, 46, 49, 51, 60, 61, 62, 65, 85, 96, 107, 164, 222, 283, 284, 285, 286, 326 💬
12 Fostamatinib 2件: Fostamatinib; Fostamatinib disodium2件: Fostamatinib ,
Fostamatinib disodium 💬 		1件: SYK 💬 17件: B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Coronavirus disease - COVID-19, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagocytosis, Herpes simplex virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, NF-kappa B signaling pathway, Natural killer cell mediated cytotoxicity, Neutrophil extracellular trap formation, Osteoclast differentiation, PI3K-Akt signaling pathway, Phospholipase D signaling pathway, Platelet activation, Tuberculosis, Viral carcinogenesis 💬5件: 46, 49, 61, 63, 66 💬
13 GL-0719 1件: GL-0719---1件: 61 💬
14 Ianalumab 1件: Ianalumab1件: Ianalumab 💬 1件: TNFRSF13C 💬 5件: Cytokine-cytokine receptor interaction, Human T-cell leukemia virus 1 infection, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Primary immunodeficiency 💬8件: 35, 46, 49, 51, 53, 61, 63, 95 💬
15 Ibrutinib 1件: Ibrutinib1件: Ibrutinib 💬 1件: BTK 💬 7件: B cell receptor signaling pathway, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, NF-kappa B signaling pathway, Osteoclast differentiation, Platelet activation, Primary immunodeficiency 💬3件: 28, 60, 61 💬
16 Iptacopan 1件: Iptacopan2件: Iptacopan ,
Iptacopan hydrochloride 💬 		1件: CFB 💬 3件: Complement and coagulation cascades, Coronavirus disease - COVID-19, Staphylococcus aureus infection 💬6件: 11, 61, 62, 66, 109, 222 💬
17 Isatuximab 1件: Isatuximab1件: Isatuximab 💬 1件: CD38 💬 6件: Calcium signaling pathway, Hematopoietic cell lineage, Nicotinate and nicotinamide metabolism, Oxytocin signaling pathway, Pancreatic secretion, Salivary secretion 💬3件: 28, 61, 283 💬
18 Levamisole 2件: Levamisole; Levamisole hydrochloride2件: Levamisole hydrochloride ,
Levamisole 💬 		--4件: 60, 61, 62, 222 💬
19 Levocetirizine 0件: 2件: Levocetirizine ,
Levocetirizine dihydrochloride 💬 		1件: HRH1 💬 4件: Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction 💬1件: 61 💬
20 Linperlisib 1件: Linperlisib---1件: 61 💬
21 Luspatercept 1件: Luspatercept1件: Luspatercept 💬 1件: ACVR2B 💬 4件: Cytokine-cytokine receptor interaction, Fluid shear stress and atherosclerosis, Signaling pathways regulating pluripotency of stem cells, TGF-beta signaling pathway 💬3件: 60, 61, 282 💬
22 Montelukast 2件: Montelukast; Montelukast sodium2件: Montelukast sodium ,
Montelukast 💬 		1件: CYSLTR1 💬 2件: Calcium signaling pathway, Neuroactive ligand-receptor interaction 💬9件: 6, 13, 19, 46, 61, 63, 85, 98, 228 💬
23 Mycophenolate mofetil 1件: Mycophenolate mofetil2件: Mycophenolate mofetil ,
Mycophenolate mofetil hydrochloride 💬 		2件: IMPDH,
IMPDH 💬 		2件: Drug metabolism - other enzymes, Purine metabolism 💬34件: 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 93, 95, 96, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬
24 Mycophenolic acid 5件: Acido micofenolico; Micofenolico acido; Mycophenolate; Mycophenolate sodium; Mycophenolic acid2件: Mycophenolate sodium ,
Mycophenolic acid 💬 		2件: IMPDH,
IMPDH 💬 		2件: Drug metabolism - other enzymes, Purine metabolism 💬37件: 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 84, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 💬
25 Nipocalimab 1件: Nipocalimab1件: Nipocalimab 💬 --6件: 11, 14, 46, 49, 53, 61 💬
26 Obexelimab 2件: Obexelimab; XMAB58711件: Obexelimab 💬 1件: CD19 💬 5件: B cell receptor signaling pathway, Epstein-Barr virus infection, Hematopoietic cell lineage, PI3K-Akt signaling pathway, Primary immunodeficiency 💬4件: 13, 49, 61, 300 💬
27 Orelabrutinib 1件: Orelabrutinib1件: Orelabrutinib 💬 1件: BTK 💬 7件: B cell receptor signaling pathway, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, NF-kappa B signaling pathway, Osteoclast differentiation, Platelet activation, Primary immunodeficiency 💬4件: 13, 49, 61, 63 💬
28 Orilanolimab 1件: Orilanolimab1件: Orilanolimab 💬 --1件: 61 💬
29 Parsaclisib 2件: INCB050465; Parsaclisib1件: Parsaclisib 💬 1件: PIK3CA_B_D 💬 103件: AGE-RAGE signaling pathway in diabetic complications, AMPK signaling pathway, Acute myeloid leukemia, Aldosterone-regulated sodium reabsorption, Alzheimer disease, Amoebiasis, Apoptosis, Autophagy - animal, Axon guidance, B cell receptor signaling pathway, Bacterial invasion of epithelial cells, Breast cancer, C-type lectin receptor signaling pathway, Carbohydrate digestion and absorption, Cellular senescence, Central carbon metabolism in cancer, Chagas disease, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Choline metabolism in cancer, Cholinergic synapse, Chronic myeloid leukemia, Colorectal cancer, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Endometrial cancer, Epstein-Barr virus infection, ErbB signaling pathway, Estrogen signaling pathway, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagocytosis, Fluid shear stress and atherosclerosis, Focal adhesion, FoxO signaling pathway, Gastric cancer, Glioma, GnRH secretion, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatitis B, Hepatitis C, Hepatocellular carcinoma, Herpes simplex virus 1 infection, Hormone signaling, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Inflammatory mediator regulation of TRP channels, Influenza A, Inositol phosphate metabolism, Insulin resistance, Insulin signaling pathway, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leukocyte transendothelial migration, Lipid and atherosclerosis, Longevity regulating pathway, Longevity regulating pathway - multiple species, Measles, Melanoma, MicroRNAs in cancer, Natural killer cell mediated cytotoxicity, Neurotrophin signaling pathway, Neutrophil extracellular trap formation, Non-alcoholic fatty liver disease, Non-small cell lung cancer, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Phosphatidylinositol signaling system, Phospholipase D signaling pathway, Platelet activation, Prion disease, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Regulation of lipolysis in adipocytes, Relaxin signaling pathway, Renal cell carcinoma, Salmonella infection, Shigellosis, Signaling pathways regulating pluripotency of stem cells, Small cell lung cancer, Sphingolipid signaling pathway, Spinocerebellar ataxia, T cell receptor signaling pathway, TNF signaling pathway, Thyroid hormone signaling pathway, Toll-like receptor signaling pathway, Type II diabetes mellitus, VEGF signaling pathway, Viral carcinogenesis, Yersinia infection, cAMP signaling pathway, mTOR signaling pathway 💬3件: 35, 53, 61 💬
30 Pegcetacoplan 1件: Pegcetacoplan1件: Pegcetacoplan 💬 1件: C3 💬 17件: Alcoholic liver disease, Chagas disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Legionellosis, Leishmaniasis, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Phagosome, Shigellosis, Staphylococcus aureus infection, Systemic lupus erythematosus, Tuberculosis, Viral carcinogenesis 💬4件: 2, 61, 62, 222 💬
31 Pentamidine 1件: Pentamidine2件: Pentamidine isethionate ,
Pentamidine 💬 		--1件: 61 💬
32 Povetacicept 1件: Povetacicept1件: Povetacicept 💬 1件: TNFRSF13B 💬 3件: Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, Primary immunodeficiency 💬3件: 61, 63, 222 💬
33 Prednisolone 3件: Prednisolona; Prednisolone; Prednisolonum1件: Prednisolone 💬 1件: NR3C1 💬 1件: Neuroactive ligand-receptor interaction 💬41件: 3, 11, 13, 14, 18, 25, 26, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 54, 56, 60, 61, 63, 64, 66, 81, 84, 85, 95, 96, 97, 113, 145, 162, 222, 251, 269, 271, 296, 299, 300 💬
34 Prednisone 2件: Prednisona; Prednisone1件: Prednisone 💬 1件: NR3C1 💬 1件: Neuroactive ligand-receptor interaction 💬54件: 2, 11, 13, 14, 18, 19, 26, 28, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 60, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 90, 93, 95, 96, 97, 113, 145, 162, 164, 205, 222, 224, 228, 251, 269, 283, 285, 288, 299, 300, 303, 307, 331 💬
35 Rilzabrutinib 1件: Rilzabrutinib1件: Rilzabrutinib 💬 1件: BTK 💬 7件: B cell receptor signaling pathway, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, NF-kappa B signaling pathway, Osteoclast differentiation, Platelet activation, Primary immunodeficiency 💬5件: 35, 61, 63, 222, 300 💬
36 Rituximab 1件: Rituximab1件: Rituximab 💬 1件: MS4A1 💬 1件: Hematopoietic cell lineage 💬52件: 11, 13, 14, 19, 26, 34, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 55, 56, 60, 61, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 162, 172, 220, 222, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331 💬
37 Sirolimus 2件: Rapamycin; Sirolimus1件: Sirolimus 💬 1件: MTOR 💬 49件: AMPK signaling pathway, Acute myeloid leukemia, Adipocytokine signaling pathway, Alzheimer disease, Amyotrophic lateral sclerosis, Apelin signaling pathway, Autophagy - animal, Autophagy - other, Breast cancer, Cellular senescence, Central carbon metabolism in cancer, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Diabetic cardiomyopathy, ErbB signaling pathway, Gastric cancer, Glioma, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatocellular carcinoma, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Huntington disease, Insulin resistance, Insulin signaling pathway, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Longevity regulating pathway, Longevity regulating pathway - multiple species, MicroRNAs in cancer, Neutrophil extracellular trap formation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Shigellosis, Spinocerebellar ataxia, Th17 cell differentiation, Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus, mTOR signaling pathway 💬46件: 2, 6, 13, 15, 17, 19, 21, 34, 35, 36, 46, 48, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 97, 98, 137, 157, 158, 192, 193, 222, 227, 256, 277, 278, 279, 280, 281, 283, 285, 300, 331 💬
38 Sutimlimab 1件: Sutimlimab1件: Sutimlimab 💬 1件: C1S 💬 5件: Complement and coagulation cascades, Coronavirus disease - COVID-19, Pertussis, Staphylococcus aureus infection, Systemic lupus erythematosus 💬1件: 61 💬
39 Tacrolimus 1件: Tacrolimus2件: Tacrolimus ,
Tacrolimus 💬 		5件: PPP3C,
PPP3C,
PPP3C,
PPP3R,
PPP3R 💬 		33件: Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬33件: 2, 6, 11, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 234, 283, 284, 285, 286, 299 💬
40 Thrombopoietin 1件: Thrombopoietin---3件: 47, 61, 63 💬
41 Trimethoprim 2件: Trimethoprim; Trimethoprim sulfate3件: Trimethoprim ,
Trimethoprim sulfate ,
Trimethoprim hydrochloride 💬 		--7件: 36, 44, 49, 60, 61, 85, 299 💬
42 Zanubrutinib 1件: Zanubrutinib1件: Zanubrutinib 💬 1件: BTK 💬 7件: B cell receptor signaling pathway, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, NF-kappa B signaling pathway, Osteoclast differentiation, Platelet activation, Primary immunodeficiency 💬6件: 13, 61, 63, 222, 300, 331 💬