Target Gene/Pathway Pathway / Gene


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No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank 指定難病告示番号
1 DDC 💬 8件: Tyrosine metabolism, Phenylalanine metabolism, Tryptophan metabolism, Serotonergic synapse, Dopaminergic synapse, Cocaine addiction, Amphetamine addiction, Alcoholism Carbidopa 💬 Carbidopa 5件: 6, 13, 17, 140, 201 💬
2 DRD1 💬 12件: Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Amphetamine addiction, Morphine addiction, Alcoholism Levodopa 💬 Levodopa 6件: 6, 17, 90, 140, 164, 201 💬
3 DRD2 💬 10件: Rap1 signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Alcoholism Levodopa 💬 Levodopa 6件: 6, 17, 90, 140, 164, 201 💬
4 DRD3 💬 4件: Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Dopaminergic synapse Levodopa 💬 Levodopa 6件: 6, 17, 90, 140, 164, 201 💬
5 DRD4 💬 4件: Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Dopaminergic synapse Levodopa 💬 Levodopa 6件: 6, 17, 90, 140, 164, 201 💬
6 DRD5 💬 6件: Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Dopaminergic synapse Levodopa 💬 Levodopa 6件: 6, 17, 90, 140, 164, 201 💬
7 GABRA 💬 7件: Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Gaboxadol 💬 Gaboxadol 2件: 201, 206 💬
8 GABRA 💬 7件: Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Gaboxadol 💬 Gaboxadol 2件: 201, 206 💬
9 GABRA 💬 7件: Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Gaboxadol 💬 Gaboxadol 2件: 201, 206 💬
10 GABRA 💬 7件: Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Gaboxadol 💬 Gaboxadol 2件: 201, 206 💬
11 GABRA 💬 7件: Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Gaboxadol 💬 Gaboxadol 2件: 201, 206 💬
12 GABRA 💬 7件: Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Gaboxadol 💬 Gaboxadol 2件: 201, 206 💬
13 GABRA 💬 7件: Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Alogabat 💬 Alogabat 1件: 201 💬
14 GABRB 💬 7件: Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Retrograde endocannabinoid signaling, Serotonergic synapse, GABAergic synapse, Morphine addiction, Nicotine addiction Gaboxadol 💬 Gaboxadol 2件: 201, 206 💬
15 GABRB 💬 7件: Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Retrograde endocannabinoid signaling, Serotonergic synapse, GABAergic synapse, Morphine addiction, Nicotine addiction Gaboxadol 💬 Gaboxadol 2件: 201, 206 💬
16 GABRB 💬 7件: Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Retrograde endocannabinoid signaling, Serotonergic synapse, GABAergic synapse, Morphine addiction, Nicotine addiction Gaboxadol 💬 Gaboxadol 2件: 201, 206 💬
17 GABRD 💬 6件: Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Gaboxadol 💬 Gaboxadol 2件: 201, 206 💬
18 GABRE 💬 6件: Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Gaboxadol 💬 Gaboxadol 2件: 201, 206 💬
19 GABRG 💬 6件: Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Gaboxadol 💬 Gaboxadol 2件: 201, 206 💬
20 GABRG 💬 6件: Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Gaboxadol 💬 Gaboxadol 2件: 201, 206 💬
21 GABRG 💬 6件: Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Gaboxadol 💬 Gaboxadol 2件: 201, 206 💬
22 GABRP 💬 6件: Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Gaboxadol 💬 Gaboxadol 2件: 201, 206 💬
23 GABRQ 💬 6件: Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Gaboxadol 💬 Gaboxadol 2件: 201, 206 💬