Target Gene/Pathway Pathway / Gene

  

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No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank 指定難病告示番号
1 GUSB 💬 6件: Pentose and glucuronate interconversions, Ascorbate and aldarate metabolism, Glycosaminoglycan degradation, Porphyrin metabolism, Drug metabolism - other enzymes, Lysosome biogenesis Vestronidase alfa 💬 Vestronidase alfa 1件: 19 💬
2 HPRT1 💬 2件: Purine metabolism, Drug metabolism - other enzymes Mercaptopurine 💬 Mercaptopurine 4件: 65, 96, 97, 164 💬
3 HPRT1 💬 2件: Purine metabolism, Drug metabolism - other enzymes Mercaptopurine 💬 Mercaptopurine 4件: 65, 96, 97, 164 💬
4 IMPDH1 💬 2件: Purine metabolism, Drug metabolism - other enzymes Mycophenolic acid 💬 Mycophenolic acid 11件: 11, 43, 49, 51, 53, 60, 66, 96, 222, 223, 228 💬
5 IMPDH1 💬 2件: Purine metabolism, Drug metabolism - other enzymes Mizoribine 💬 Mizoribine 8件: 46, 49, 51, 53, 66, 94, 222, 224 💬
6 IMPDH1 💬 2件: Purine metabolism, Drug metabolism - other enzymes Mycophenolate sodium 💬 Mycophenolic acid 11件: 11, 43, 49, 51, 53, 60, 66, 96, 222, 223, 228 💬
7 IMPDH1 💬 2件: Purine metabolism, Drug metabolism - other enzymes Mycophenolate mofetil hydrochloride 💬 Mycophenolate mofetil 38件: 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 46, 49, 51, 53, 57, 60, 61, 62, 63, 65, 66, 93, 95, 96, 118, 162, 164, 222, 223, 224, 226, 234, 283, 284, 285, 300 💬
8 IMPDH1 💬 2件: Purine metabolism, Drug metabolism - other enzymes Mycophenolate mofetil 💬 Mycophenolate mofetil 38件: 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 46, 49, 51, 53, 57, 60, 61, 62, 63, 65, 66, 93, 95, 96, 118, 162, 164, 222, 223, 224, 226, 234, 283, 284, 285, 300 💬
9 IMPDH2 💬 2件: Purine metabolism, Drug metabolism - other enzymes Mycophenolate sodium 💬 Mycophenolic acid 11件: 11, 43, 49, 51, 53, 60, 66, 96, 222, 223, 228 💬
10 IMPDH2 💬 2件: Purine metabolism, Drug metabolism - other enzymes Mycophenolate mofetil hydrochloride 💬 Mycophenolate mofetil 38件: 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 46, 49, 51, 53, 57, 60, 61, 62, 63, 65, 66, 93, 95, 96, 118, 162, 164, 222, 223, 224, 226, 234, 283, 284, 285, 300 💬
11 IMPDH2 💬 2件: Purine metabolism, Drug metabolism - other enzymes Mycophenolate mofetil 💬 Mycophenolate mofetil 38件: 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 46, 49, 51, 53, 57, 60, 61, 62, 63, 65, 66, 93, 95, 96, 118, 162, 164, 222, 223, 224, 226, 234, 283, 284, 285, 300 💬
12 IMPDH2 💬 2件: Purine metabolism, Drug metabolism - other enzymes Mycophenolic acid 💬 Mycophenolic acid 11件: 11, 43, 49, 51, 53, 60, 66, 96, 222, 223, 228 💬
13 IMPDH2 💬 2件: Purine metabolism, Drug metabolism - other enzymes Mizoribine 💬 Mizoribine 8件: 46, 49, 51, 53, 66, 94, 222, 224 💬
14 MPO 💬 5件: Drug metabolism - other enzymes, Phagocytosis, Neutrophil extracellular trap formation, Transcriptional misregulation in cancer, Acute myeloid leukemia Verdiperstat 💬 Verdiperstat 3件: 2, 17, 127 💬
15 RRM1 💬 4件: Purine metabolism, Pyrimidine metabolism, Glutathione metabolism, Drug metabolism - other enzymes Clofarabine 💬 Clofarabine 9件: 19, 20, 40, 46, 49, 60, 96, 234, 326 💬
16 RRM1 💬 4件: Purine metabolism, Pyrimidine metabolism, Glutathione metabolism, Drug metabolism - other enzymes Cladribine 💬 Cladribine 3件: 11, 13, 94 💬
17 RRM1 💬 4件: Purine metabolism, Pyrimidine metabolism, Glutathione metabolism, Drug metabolism - other enzymes Fludarabine 💬 Fludarabine 30件: 11, 13, 14, 16, 19, 28, 34, 35, 36, 44, 46, 49, 50, 51, 60, 61, 62, 63, 65, 85, 96, 107, 164, 222, 223, 283, 284, 285, 286, 326 💬
18 RRM1 💬 4件: Purine metabolism, Pyrimidine metabolism, Glutathione metabolism, Drug metabolism - other enzymes Fludarabine phosphate 💬 Fludarabine 30件: 11, 13, 14, 16, 19, 28, 34, 35, 36, 44, 46, 49, 50, 51, 60, 61, 62, 63, 65, 85, 96, 107, 164, 222, 223, 283, 284, 285, 286, 326 💬
19 RRM2 💬 5件: Purine metabolism, Pyrimidine metabolism, Glutathione metabolism, Drug metabolism - other enzymes, p53 signaling pathway Hydroxyurea 💬 Hydroxyurea 10件: 3, 13, 19, 20, 46, 65, 85, 86, 107, 284 💬
20 TK2 💬 2件: Pyrimidine metabolism, Drug metabolism - other enzymes Doxribtimine 💬 Thymidine 2件: 215, 216 💬
21 XDH 💬 4件: Purine metabolism, Caffeine metabolism, Drug metabolism - other enzymes, Peroxisome Allopurinol 💬 Allopurinol 7件: 6, 46, 57, 60, 66, 96, 97 💬
22 XDH 💬 4件: Purine metabolism, Caffeine metabolism, Drug metabolism - other enzymes, Peroxisome Febuxostat 💬 Febuxostat 5件: 2, 6, 13, 67, 97 💬
23 XDH 💬 4件: Purine metabolism, Caffeine metabolism, Drug metabolism - other enzymes, Peroxisome Febuxostat hydrate 💬 Febuxostat 5件: 2, 6, 13, 67, 97 💬
24 XDH 💬 4件: Purine metabolism, Caffeine metabolism, Drug metabolism - other enzymes, Peroxisome Allopurinol sodium 💬 Allopurinol 7件: 6, 46, 57, 60, 66, 96, 97 💬