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Target Gene/Pathway Pathway / Gene

Search results

No.

KEGG GENES

KEGG PATHWAY

KEGG DRUG

DrugBank

Disease ID

1

[4] Oocyte meiosis, Pathways in cancer, Chemical carcinogenesis - receptor activation, Prostate cancer

Oxandrolone 💬

[2] 211, 285 💬

2

[7] Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Vascular smooth muscle contraction, Renin secretion, Pathways in cancer

Ambrisentan 💬

[8] 51, 66, 84, 85, 86, 88, 210, 211 💬

Disease ID	Name
51	Scleroderma
66	IgA nephropathy
84	Sarcoidosis
85	Idiopathic interstitial pneumonia
86	Pulmonary arterial hypertension
88	Chronic thromboembolic pulmonary hypertension
210	Single Ventricle
211	Hypoplastic left heart syndrome

3

[7] Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Vascular smooth muscle contraction, Renin secretion, Pathways in cancer

[11] 40, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬

Disease ID	Name
40	Takayasu arteritis
41	Giant cell arteritis
47	Buerger disease
51	Scleroderma
84	Sarcoidosis
85	Idiopathic interstitial pneumonia
86	Pulmonary arterial hypertension
88	Chronic thromboembolic pulmonary hypertension
210	Single Ventricle
211	Hypoplastic left heart syndrome
212	Tricuspid atresia

4

[7] Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Vascular smooth muscle contraction, Renin secretion, Pathways in cancer

[11] 40, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬

Disease ID	Name
40	Takayasu arteritis
41	Giant cell arteritis
47	Buerger disease
51	Scleroderma
84	Sarcoidosis
85	Idiopathic interstitial pneumonia
86	Pulmonary arterial hypertension
88	Chronic thromboembolic pulmonary hypertension
210	Single Ventricle
211	Hypoplastic left heart syndrome
212	Tricuspid atresia

5

[6] Calcium signaling pathway, cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, Melanogenesis, Relaxin signaling pathway, Pathways in cancer

[11] 40, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬

Disease ID	Name
40	Takayasu arteritis
41	Giant cell arteritis
47	Buerger disease
51	Scleroderma
84	Sarcoidosis
85	Idiopathic interstitial pneumonia
86	Pulmonary arterial hypertension
88	Chronic thromboembolic pulmonary hypertension
210	Single Ventricle
211	Hypoplastic left heart syndrome
212	Tricuspid atresia

6

[6] Calcium signaling pathway, cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, Melanogenesis, Relaxin signaling pathway, Pathways in cancer

[11] 40, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬

Disease ID	Name
40	Takayasu arteritis
41	Giant cell arteritis
47	Buerger disease
51	Scleroderma
84	Sarcoidosis
85	Idiopathic interstitial pneumonia
86	Pulmonary arterial hypertension
88	Chronic thromboembolic pulmonary hypertension
210	Single Ventricle
211	Hypoplastic left heart syndrome
212	Tricuspid atresia

7

[1] Neuroactive ligand-receptor interaction

Methylprednisolone 💬

Methylprednisolone

[48] 2, 6, 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 95, 96, 97, 127, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296, 300 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis
6	Parkinson disease
11	Myasthenia gravis
13	Multiple sclerosis
14	Chronic inflammatory demyelinating polyneuropathy
18	Spinocerebellar degeneration
19	Lysosomal storage disease
25	Progressive multifocal leukoencephalopathy
26	HTLV-1-associated myelopathy
35	Pemphigus
38	Stevens-Johnson syndrome
39	Toxic epidermal necrolysis
40	Takayasu arteritis
41	Giant cell arteritis
42	Polyarteritis nodosa
43	Microscopic polyangiitis
45	Eosinophilic granulomatosis with Polyangiitis
46	Malignant rheumatoid arthritis
49	Systemic lupus erythematosus
50	Dermatomyositis
51	Scleroderma
60	Aplastic anemia
62	Paroxysmal nocturnal hemoglobinuria
63	Idiopathic thrombocytopenic purpura
64	Thrombotic thrombocytopenic purpura
65	Primary immunodeficiency
66	IgA nephropathy
83	Addison disease
84	Sarcoidosis
85	Idiopathic interstitial pneumonia
86	Pulmonary arterial hypertension
93	Primary biliary cholangitis
95	Autoimmune hepatitis
96	Crohn disease
97	Ulcerative colitis
127	Frontotemporal lobar degeneration
162	Pemphigoid
164	Oculocutaneous albinism
211	Hypoplastic left heart syndrome
220	Rapidly progressive glomerulonephritis
222	Primary nephrotic syndrome
224	Purpura nephritis
271	Ankylosing spondylitis
283	Acquired pure red cell aplasia
284	Diamond-Blackfan anemia
285	Fanconi anemia
296	Biliary atresia
300	IgG4-related disease

8

[1] Neuroactive ligand-receptor interaction

Methylprednisolone acetate 💬

Methylprednisolone

[48] 2, 6, 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 95, 96, 97, 127, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296, 300 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis
6	Parkinson disease
11	Myasthenia gravis
13	Multiple sclerosis
14	Chronic inflammatory demyelinating polyneuropathy
18	Spinocerebellar degeneration
19	Lysosomal storage disease
25	Progressive multifocal leukoencephalopathy
26	HTLV-1-associated myelopathy
35	Pemphigus
38	Stevens-Johnson syndrome
39	Toxic epidermal necrolysis
40	Takayasu arteritis
41	Giant cell arteritis
42	Polyarteritis nodosa
43	Microscopic polyangiitis
45	Eosinophilic granulomatosis with Polyangiitis
46	Malignant rheumatoid arthritis
49	Systemic lupus erythematosus
50	Dermatomyositis
51	Scleroderma
60	Aplastic anemia
62	Paroxysmal nocturnal hemoglobinuria
63	Idiopathic thrombocytopenic purpura
64	Thrombotic thrombocytopenic purpura
65	Primary immunodeficiency
66	IgA nephropathy
83	Addison disease
84	Sarcoidosis
85	Idiopathic interstitial pneumonia
86	Pulmonary arterial hypertension
93	Primary biliary cholangitis
95	Autoimmune hepatitis
96	Crohn disease
97	Ulcerative colitis
127	Frontotemporal lobar degeneration
162	Pemphigoid
164	Oculocutaneous albinism
211	Hypoplastic left heart syndrome
220	Rapidly progressive glomerulonephritis
222	Primary nephrotic syndrome
224	Purpura nephritis
271	Ankylosing spondylitis
283	Acquired pure red cell aplasia
284	Diamond-Blackfan anemia
285	Fanconi anemia
296	Biliary atresia
300	IgG4-related disease

9

[2] Purine metabolism, cGMP-PKG signaling pathway

Sildenafil citrate 💬

[14] 6, 46, 51, 85, 86, 113, 210, 211, 212, 225, 226, 278, 294, 299 💬

Disease ID	Name
6	Parkinson disease
46	Malignant rheumatoid arthritis
51	Scleroderma
85	Idiopathic interstitial pneumonia
86	Pulmonary arterial hypertension
113	Muscular dystrophy
210	Single Ventricle
211	Hypoplastic left heart syndrome
212	Tricuspid atresia
225	Congenital nephrogenic diabetes insipidus
226	Interstitial cystitis with Hunners ulcer
278	Huge lymphatic malformation with cervicofacial lesion
294	Congenital diaphragmatic hernia
299	Cystic fibrosis

10

[2] Purine metabolism, cGMP-PKG signaling pathway

Sildenafil 💬

[14] 6, 46, 51, 85, 86, 113, 210, 211, 212, 225, 226, 278, 294, 299 💬

Disease ID	Name
6	Parkinson disease
46	Malignant rheumatoid arthritis
51	Scleroderma
85	Idiopathic interstitial pneumonia
86	Pulmonary arterial hypertension
113	Muscular dystrophy
210	Single Ventricle
211	Hypoplastic left heart syndrome
212	Tricuspid atresia
225	Congenital nephrogenic diabetes insipidus
226	Interstitial cystitis with Hunners ulcer
278	Huge lymphatic malformation with cervicofacial lesion
294	Congenital diaphragmatic hernia
299	Cystic fibrosis