Target Gene/Pathway Pathway / Gene

  

Search results

No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank Disease ID
1 CACNA1B 💬 [15] MAPK signaling pathway, Calcium signaling pathway, Synaptic vesicle cycle, Retrograde endocannabinoid signaling, Cholinergic synapse, Serotonergic synapse, GABAergic synapse, Dopaminergic synapse, Type II diabetes mellitus, Huntington disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Morphine addiction, Nicotine addiction, Chemical carcinogenesis - receptor activation Cilnidipine 💬 Cilnidipine [1] 67 💬
2 SLC18A1_2 💬 [8] Neuroactive ligand signaling, Synaptic vesicle cycle, Serotonergic synapse, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Amphetamine addiction, Alcoholism Tetrabenazine 💬 Tetrabenazine [1] 8 💬
3 SLC18A1_2 💬 [8] Neuroactive ligand signaling, Synaptic vesicle cycle, Serotonergic synapse, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Amphetamine addiction, Alcoholism Midomafetamine hydrochloride 💬 Midomafetamine [1] 72 💬
4 SLC18A1_2 💬 [8] Neuroactive ligand signaling, Synaptic vesicle cycle, Serotonergic synapse, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Amphetamine addiction, Alcoholism Midomafetamine 💬 Midomafetamine [1] 72 💬
5 SLC18A1_2 💬 [8] Neuroactive ligand signaling, Synaptic vesicle cycle, Serotonergic synapse, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Amphetamine addiction, Alcoholism Deutetrabenazine 💬 Deutetrabenazine [1] 8 💬
6 SLC18A1_2 💬 [8] Neuroactive ligand signaling, Synaptic vesicle cycle, Serotonergic synapse, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Amphetamine addiction, Alcoholism Valbenazine 💬 Valbenazine [1] 8 💬
7 SLC18A1_2 💬 [8] Neuroactive ligand signaling, Synaptic vesicle cycle, Serotonergic synapse, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Amphetamine addiction, Alcoholism Valbenazine tosylate 💬 Valbenazine [1] 8 💬
8 SLC6A1 💬 [3] Neuroactive ligand signaling, Synaptic vesicle cycle, GABAergic synapse Gabapentin 💬 Gabapentin [5] 6, 13, 19, 70, 298 💬
9 SLC6A2 💬 [2] Neuroactive ligand signaling, Synaptic vesicle cycle Methylphenidate 💬 Methylphenidate [7] 6, 13, 34, 84, 113, 179, 206 💬
10 SLC6A2 💬 [2] Neuroactive ligand signaling, Synaptic vesicle cycle Amitriptyline 💬 Amitriptyline [3] 97, 226, 299 💬
11 SLC6A2 💬 [2] Neuroactive ligand signaling, Synaptic vesicle cycle Atomoxetine hydrochloride 💬 Atomoxetine [4] 6, 8, 13, 230 💬
12 SLC6A2 💬 [2] Neuroactive ligand signaling, Synaptic vesicle cycle Milnacipran hydrochloride 💬 Milnacipran [2] 46, 49 💬
13 SLC6A2 💬 [2] Neuroactive ligand signaling, Synaptic vesicle cycle Methylphenidate hydrochloride 💬 Methylphenidate [7] 6, 13, 34, 84, 113, 179, 206 💬
14 SLC6A2 💬 [2] Neuroactive ligand signaling, Synaptic vesicle cycle Duloxetine hydrochloride 💬 Duloxetine [2] 6, 13 💬
15 SLC6A2 💬 [2] Neuroactive ligand signaling, Synaptic vesicle cycle Solriamfetol 💬 Solriamfetol [1] 13 💬
16 SLC6A2 💬 [2] Neuroactive ligand signaling, Synaptic vesicle cycle Venlafaxine 💬 Venlafaxine [4] 6, 13, 46, 97 💬
17 SLC6A2 💬 [2] Neuroactive ligand signaling, Synaptic vesicle cycle Doxepin 💬 Doxepin [1] 6 💬
18 SLC6A2 💬 [2] Neuroactive ligand signaling, Synaptic vesicle cycle Amitriptyline hydrochloride 💬 Amitriptyline [3] 97, 226, 299 💬
19 SLC6A2 💬 [2] Neuroactive ligand signaling, Synaptic vesicle cycle Milnacipran 💬 Milnacipran [2] 46, 49 💬
20 SLC6A2 💬 [2] Neuroactive ligand signaling, Synaptic vesicle cycle Phentermine hydrochloride 💬 Phentermine [1] 97 💬
21 SLC6A2 💬 [2] Neuroactive ligand signaling, Synaptic vesicle cycle Nortriptyline 💬 Nortriptyline [2] 6, 226 💬
22 SLC6A2 💬 [2] Neuroactive ligand signaling, Synaptic vesicle cycle Bupropion 💬 Bupropion [6] 8, 18, 21, 96, 97, 171 💬
23 SLC6A2 💬 [2] Neuroactive ligand signaling, Synaptic vesicle cycle Doxepin hydrochloride 💬 Doxepin [1] 6 💬
24 SLC6A2 💬 [2] Neuroactive ligand signaling, Synaptic vesicle cycle Phentermine 💬 Phentermine [1] 97 💬
25 SLC6A2 💬 [2] Neuroactive ligand signaling, Synaptic vesicle cycle Atomoxetine 💬 Atomoxetine [4] 6, 8, 13, 230 💬
26 SLC6A2 💬 [2] Neuroactive ligand signaling, Synaptic vesicle cycle Desipramine hydrochloride 💬 Desipramine [1] 121 💬
27 SLC6A2 💬 [2] Neuroactive ligand signaling, Synaptic vesicle cycle Lisdexamfetamine 💬 Lisdexamfetamine [1] 13 💬
28 SLC6A2 💬 [2] Neuroactive ligand signaling, Synaptic vesicle cycle Bupropion hydrobromide 💬 Bupropion [6] 8, 18, 21, 96, 97, 171 💬
29 SLC6A2 💬 [2] Neuroactive ligand signaling, Synaptic vesicle cycle Nortriptyline hydrochloride 💬 Nortriptyline [2] 6, 226 💬
30 SLC6A2 💬 [2] Neuroactive ligand signaling, Synaptic vesicle cycle Bupropion hydrochloride 💬 Bupropion [6] 8, 18, 21, 96, 97, 171 💬
31 SLC6A2 💬 [2] Neuroactive ligand signaling, Synaptic vesicle cycle Solriamfetol hydrochloride 💬 Solriamfetol [1] 13 💬
32 SLC6A2 💬 [2] Neuroactive ligand signaling, Synaptic vesicle cycle Duloxetine 💬 Duloxetine [2] 6, 13 💬
33 SLC6A2 💬 [2] Neuroactive ligand signaling, Synaptic vesicle cycle Desipramine 💬 Desipramine [1] 121 💬
34 SLC6A2 💬 [2] Neuroactive ligand signaling, Synaptic vesicle cycle Ampreloxetine 💬 Ampreloxetine [2] 6, 17 💬
35 SLC6A2 💬 [2] Neuroactive ligand signaling, Synaptic vesicle cycle Lisdexamfetamine dimesylate 💬 Lisdexamfetamine [1] 13 💬
36 SLC6A2 💬 [2] Neuroactive ligand signaling, Synaptic vesicle cycle Venlafaxine hydrochloride 💬 Venlafaxine [4] 6, 13, 46, 97 💬
37 SLC6A2 💬 [2] Neuroactive ligand signaling, Synaptic vesicle cycle Amoxapine 💬 Amoxapine [1] 46 💬
38 SLC6A2 💬 [2] Neuroactive ligand signaling, Synaptic vesicle cycle Midomafetamine hydrochloride 💬 Midomafetamine [1] 72 💬
39 SLC6A2 💬 [2] Neuroactive ligand signaling, Synaptic vesicle cycle Venlafaxine besylate monohydrate 💬 Venlafaxine [4] 6, 13, 46, 97 💬
40 SLC6A2 💬 [2] Neuroactive ligand signaling, Synaptic vesicle cycle Midomafetamine 💬 Midomafetamine [1] 72 💬
41 SLC6A3 💬 [8] Neuroactive ligand signaling, Synaptic vesicle cycle, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Alcoholism Bupropion hydrochloride 💬 Bupropion [6] 8, 18, 21, 96, 97, 171 💬
42 SLC6A3 💬 [8] Neuroactive ligand signaling, Synaptic vesicle cycle, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Alcoholism Solriamfetol 💬 Solriamfetol [1] 13 💬
43 SLC6A3 💬 [8] Neuroactive ligand signaling, Synaptic vesicle cycle, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Alcoholism Lisdexamfetamine dimesylate 💬 Lisdexamfetamine [1] 13 💬
44 SLC6A3 💬 [8] Neuroactive ligand signaling, Synaptic vesicle cycle, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Alcoholism Bupropion hydrobromide 💬 Bupropion [6] 8, 18, 21, 96, 97, 171 💬
45 SLC6A3 💬 [8] Neuroactive ligand signaling, Synaptic vesicle cycle, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Alcoholism Phentermine 💬 Phentermine [1] 97 💬
46 SLC6A3 💬 [8] Neuroactive ligand signaling, Synaptic vesicle cycle, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Alcoholism Lisdexamfetamine 💬 Lisdexamfetamine [1] 13 💬
47 SLC6A3 💬 [8] Neuroactive ligand signaling, Synaptic vesicle cycle, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Alcoholism Midomafetamine 💬 Midomafetamine [1] 72 💬
48 SLC6A3 💬 [8] Neuroactive ligand signaling, Synaptic vesicle cycle, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Alcoholism Phentermine hydrochloride 💬 Phentermine [1] 97 💬
49 SLC6A3 💬 [8] Neuroactive ligand signaling, Synaptic vesicle cycle, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Alcoholism Ioflupane I 123 💬 Ioflupane I-123 [1] 6 💬
50 SLC6A3 💬 [8] Neuroactive ligand signaling, Synaptic vesicle cycle, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Alcoholism Solriamfetol hydrochloride 💬 Solriamfetol [1] 13 💬
51 SLC6A3 💬 [8] Neuroactive ligand signaling, Synaptic vesicle cycle, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Alcoholism Midomafetamine hydrochloride 💬 Midomafetamine [1] 72 💬
52 SLC6A3 💬 [8] Neuroactive ligand signaling, Synaptic vesicle cycle, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Alcoholism Methylphenidate 💬 Methylphenidate [7] 6, 13, 34, 84, 113, 179, 206 💬
53 SLC6A3 💬 [8] Neuroactive ligand signaling, Synaptic vesicle cycle, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Alcoholism Armodafinil 💬 Armodafinil [3] 6, 13, 84 💬
54 SLC6A3 💬 [8] Neuroactive ligand signaling, Synaptic vesicle cycle, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Alcoholism Bupropion 💬 Bupropion [6] 8, 18, 21, 96, 97, 171 💬
55 SLC6A3 💬 [8] Neuroactive ligand signaling, Synaptic vesicle cycle, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Alcoholism Methylphenidate hydrochloride 💬 Methylphenidate [7] 6, 13, 34, 84, 113, 179, 206 💬
56 SLC6A4 💬 [3] Neuroactive ligand signaling, Synaptic vesicle cycle, Serotonergic synapse Citalopram hydrobromide 💬 Citalopram [5] 6, 13, 46, 98, 127 💬
57 SLC6A4 💬 [3] Neuroactive ligand signaling, Synaptic vesicle cycle, Serotonergic synapse Doxepin 💬 Doxepin [1] 6 💬
58 SLC6A4 💬 [3] Neuroactive ligand signaling, Synaptic vesicle cycle, Serotonergic synapse Trazodone 💬 Trazodone [1] 2 💬
59 SLC6A4 💬 [3] Neuroactive ligand signaling, Synaptic vesicle cycle, Serotonergic synapse Vortioxetine hydrobromide 💬 Vortioxetine [2] 6, 127 💬
60 SLC6A4 💬 [3] Neuroactive ligand signaling, Synaptic vesicle cycle, Serotonergic synapse Citalopram 💬 Citalopram [5] 6, 13, 46, 98, 127 💬
61 SLC6A4 💬 [3] Neuroactive ligand signaling, Synaptic vesicle cycle, Serotonergic synapse Duloxetine 💬 Duloxetine [2] 6, 13 💬
62 SLC6A4 💬 [3] Neuroactive ligand signaling, Synaptic vesicle cycle, Serotonergic synapse Nortriptyline 💬 Nortriptyline [2] 6, 226 💬
63 SLC6A4 💬 [3] Neuroactive ligand signaling, Synaptic vesicle cycle, Serotonergic synapse Amitriptyline hydrochloride 💬 Amitriptyline [3] 97, 226, 299 💬
64 SLC6A4 💬 [3] Neuroactive ligand signaling, Synaptic vesicle cycle, Serotonergic synapse Trazodone hydrochloride 💬 Trazodone [1] 2 💬
65 SLC6A4 💬 [3] Neuroactive ligand signaling, Synaptic vesicle cycle, Serotonergic synapse Fenfluramine 💬 Fenfluramine [4] 140, 144, 145, 149 💬
66 SLC6A4 💬 [3] Neuroactive ligand signaling, Synaptic vesicle cycle, Serotonergic synapse Midomafetamine 💬 Midomafetamine [1] 72 💬
67 SLC6A4 💬 [3] Neuroactive ligand signaling, Synaptic vesicle cycle, Serotonergic synapse Sertraline 💬 Sertraline [3] 6, 158, 206 💬
68 SLC6A4 💬 [3] Neuroactive ligand signaling, Synaptic vesicle cycle, Serotonergic synapse Desipramine hydrochloride 💬 Desipramine [1] 121 💬
69 SLC6A4 💬 [3] Neuroactive ligand signaling, Synaptic vesicle cycle, Serotonergic synapse Nortriptyline hydrochloride 💬 Nortriptyline [2] 6, 226 💬
70 SLC6A4 💬 [3] Neuroactive ligand signaling, Synaptic vesicle cycle, Serotonergic synapse Desipramine 💬 Desipramine [1] 121 💬
71 SLC6A4 💬 [3] Neuroactive ligand signaling, Synaptic vesicle cycle, Serotonergic synapse Midomafetamine hydrochloride 💬 Midomafetamine [1] 72 💬
72 SLC6A4 💬 [3] Neuroactive ligand signaling, Synaptic vesicle cycle, Serotonergic synapse Amitriptyline 💬 Amitriptyline [3] 97, 226, 299 💬
73 SLC6A4 💬 [3] Neuroactive ligand signaling, Synaptic vesicle cycle, Serotonergic synapse Milnacipran hydrochloride 💬 Milnacipran [2] 46, 49 💬
74 SLC6A4 💬 [3] Neuroactive ligand signaling, Synaptic vesicle cycle, Serotonergic synapse Paroxetine hydrochloride hemihydrate 💬 Paroxetine [4] 6, 13, 46, 85 💬
75 SLC6A4 💬 [3] Neuroactive ligand signaling, Synaptic vesicle cycle, Serotonergic synapse Fenfluramine hydrochloride 💬 Fenfluramine [4] 140, 144, 145, 149 💬
76 SLC6A4 💬 [3] Neuroactive ligand signaling, Synaptic vesicle cycle, Serotonergic synapse Sertraline hydrochloride 💬 Sertraline [3] 6, 158, 206 💬
77 SLC6A4 💬 [3] Neuroactive ligand signaling, Synaptic vesicle cycle, Serotonergic synapse Escitalopram 💬 Escitalopram [5] 2, 6, 13, 46, 77 💬
78 SLC6A4 💬 [3] Neuroactive ligand signaling, Synaptic vesicle cycle, Serotonergic synapse Milnacipran 💬 Milnacipran [2] 46, 49 💬
79 SLC6A4 💬 [3] Neuroactive ligand signaling, Synaptic vesicle cycle, Serotonergic synapse Doxepin hydrochloride 💬 Doxepin [1] 6 💬
80 SLC6A4 💬 [3] Neuroactive ligand signaling, Synaptic vesicle cycle, Serotonergic synapse Venlafaxine besylate monohydrate 💬 Venlafaxine [4] 6, 13, 46, 97 💬
81 SLC6A4 💬 [3] Neuroactive ligand signaling, Synaptic vesicle cycle, Serotonergic synapse Duloxetine hydrochloride 💬 Duloxetine [2] 6, 13 💬
82 SLC6A4 💬 [3] Neuroactive ligand signaling, Synaptic vesicle cycle, Serotonergic synapse Venlafaxine hydrochloride 💬 Venlafaxine [4] 6, 13, 46, 97 💬
83 SLC6A4 💬 [3] Neuroactive ligand signaling, Synaptic vesicle cycle, Serotonergic synapse Paroxetine hydrochloride 💬 Paroxetine [4] 6, 13, 46, 85 💬
84 SLC6A4 💬 [3] Neuroactive ligand signaling, Synaptic vesicle cycle, Serotonergic synapse Phentermine 💬 Phentermine [1] 97 💬
85 SLC6A4 💬 [3] Neuroactive ligand signaling, Synaptic vesicle cycle, Serotonergic synapse Fluoxetine hydrochloride 💬 Fluoxetine [3] 13, 17, 86 💬
86 SLC6A4 💬 [3] Neuroactive ligand signaling, Synaptic vesicle cycle, Serotonergic synapse Amoxapine 💬 Amoxapine [1] 46 💬
87 SLC6A4 💬 [3] Neuroactive ligand signaling, Synaptic vesicle cycle, Serotonergic synapse Vortioxetine 💬 Vortioxetine [2] 6, 127 💬
88 SLC6A4 💬 [3] Neuroactive ligand signaling, Synaptic vesicle cycle, Serotonergic synapse Ampreloxetine 💬 Ampreloxetine [2] 6, 17 💬
89 SLC6A4 💬 [3] Neuroactive ligand signaling, Synaptic vesicle cycle, Serotonergic synapse Phentermine hydrochloride 💬 Phentermine [1] 97 💬
90 SLC6A4 💬 [3] Neuroactive ligand signaling, Synaptic vesicle cycle, Serotonergic synapse Escitalopram oxalate 💬 Escitalopram [5] 2, 6, 13, 46, 77 💬
91 SLC6A4 💬 [3] Neuroactive ligand signaling, Synaptic vesicle cycle, Serotonergic synapse Paroxetine mesylate 💬 Paroxetine [4] 6, 13, 46, 85 💬
92 SLC6A4 💬 [3] Neuroactive ligand signaling, Synaptic vesicle cycle, Serotonergic synapse Paroxetine 💬 Paroxetine [4] 6, 13, 46, 85 💬
93 SLC6A4 💬 [3] Neuroactive ligand signaling, Synaptic vesicle cycle, Serotonergic synapse Venlafaxine 💬 Venlafaxine [4] 6, 13, 46, 97 💬
94 SLC6A4 💬 [3] Neuroactive ligand signaling, Synaptic vesicle cycle, Serotonergic synapse Fluoxetine 💬 Fluoxetine [3] 13, 17, 86 💬
95 SLC6A5_9 💬 [2] Neuroactive ligand signaling, Synaptic vesicle cycle Bitopertin 💬 Bitopertin [1] 284 💬
96 SNAP25 💬 [2] Synaptic vesicle cycle, Insulin secretion Botulinum toxin type A 💬 Botulinum toxin type A [14] 2, 5, 6, 7, 13, 15, 17, 47, 51, 70, 113, 149, 171, 226 💬
97 SNAP25 💬 [2] Synaptic vesicle cycle, Insulin secretion Rimabotulinumtoxin B 💬 Botulinum toxin type B [3] 2, 6, 51 💬
98 SNAP25 💬 [2] Synaptic vesicle cycle, Insulin secretion Prabotulinumtoxin A 💬 Botulinum toxin type A [14] 2, 5, 6, 7, 13, 15, 17, 47, 51, 70, 113, 149, 171, 226 💬