Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. KEGG DRUG DrugBank 薬物名（臨床試験情報から抽出） KEGG GENES KEGG PATHWAY 指定難病告示番号
1 Abatacept 💬1件: Abatacept1件: Abatacept2件: CD80,
CD86 💬 		13件: Allograft rejection, Autoimmune thyroid disease, Cell adhesion molecules, Graft-versus-host disease, Intestinal immune network for IgA production, Kaposi sarcoma-associated herpesvirus infection, Rheumatoid arthritis, Systemic lupus erythematosus, Toll-like receptor signaling pathway, Transcriptional misregulation in cancer, Type I diabetes mellitus, Viral myocarditis, Virion - Adenovirus 💬26件: 2, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
2 Acetaminophen 💬1件: Acetaminophen2件: Acetaminophen; Paracetamol2件: PTGS1,
PTGS2 💬 		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Efferocytosis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬17件: 3, 6, 11, 13, 19, 34, 46, 49, 51, 70, 77, 86, 96, 222, 256, 300, 337 💬
3 Adalimumab 💬1件: Adalimumab1件: Adalimumab1件: TNF 💬 66件: AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬18件: 19, 37, 40, 41, 46, 55, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
4 Albumin human 💬1件: Albumin human3件: Albumin; Human albumin; Serum albumin--5件: 2, 11, 50, 222, 296 💬
5 Aldosterone 💬1件: Aldosterone1件: Aldosterone1件: NR3C2 💬 1件: Aldosterone-regulated sodium reabsorption 💬1件: 222 💬
6 Aliskiren 💬1件: Aliskiren1件: Aliskiren1件: REN 💬 3件: Diabetic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬3件: 66, 167, 222 💬
7 Aliskiren fumarate 💬1件: Aliskiren1件: Aliskiren1件: REN 💬 3件: Diabetic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬3件: 66, 167, 222 💬
8 Angiotensin II 💬1件: Angiotensin II2件: Angiotensin; Angiotensin II2件: AGTR1,
AGTR2 💬 		17件: AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Hormone signaling, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬5件: 17, 66, 218, 222, 224 💬
9 Angiotensin II 💬1件: Angiotensin II2件: Angiotensin; Angiotensin II2件: AGTR1,
AGTR2 💬 		17件: AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Hormone signaling, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬5件: 17, 66, 218, 222, 224 💬
10 Angiotensin II acetate 💬1件: Angiotensin II2件: Angiotensin; Angiotensin II2件: AGTR1,
AGTR2 💬 		17件: AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Hormone signaling, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬5件: 17, 66, 218, 222, 224 💬
11 Apixaban 💬1件: Apixaban1件: Apixaban1件: F10 💬 1件: Complement and coagulation cascades 💬2件: 222, 279 💬
12 Atacicept 💬1件: Atacicept2件: Atacicept; TACI-FC52件: TNFSF13,
TNFSF13B 💬 		4件: Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis 💬5件: 13, 46, 49, 66, 222 💬
13 Atrasentan hydrochloride 💬1件: Atrasentan1件: Atrasentan1件: EDNRA 💬 7件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Pathways in cancer, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬3件: 66, 218, 222 💬
14 Avacopan 💬1件: Avacopan1件: Avacopan1件: C5AR1 💬 6件: Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Staphylococcus aureus infection 💬4件: 43, 44, 66, 222 💬
15 Bardoxolone 💬1件: Bardoxolone0件: ---
16 Bardoxolone methyl 💬1件: Bardoxolone methyl1件: Bardoxolone methyl--5件: 67, 84, 85, 86, 218 💬
17 Basiliximab 💬1件: Basiliximab1件: Basiliximab1件: IL2RA 💬 11件: Cytokine-cytokine receptor interaction, Endocytosis, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, JAK-STAT signaling pathway, Measles, PI3K-Akt signaling pathway, Pathways in cancer, Th1 and Th2 cell differentiation, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬5件: 2, 50, 97, 222, 228 💬
18 Belimumab 💬1件: Belimumab1件: Belimumab1件: TNFSF13B 💬 4件: Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis 💬13件: 11, 13, 43, 44, 46, 49, 51, 53, 63, 66, 95, 222, 296 💬
19 Bleselumab 💬1件: Bleselumab1件: Bleselumab1件: TNFRSF5 💬 17件: Allograft rejection, Asthma, Autoimmune thyroid disease, Cell adhesion molecules, Cytokine-cytokine receptor interaction, Epstein-Barr virus infection, Human T-cell leukemia virus 1 infection, Intestinal immune network for IgA production, Lipid and atherosclerosis, Malaria, NF-kappa B signaling pathway, Primary immunodeficiency, Systemic lupus erythematosus, Toll-like receptor signaling pathway, Toxoplasmosis, Transcriptional misregulation in cancer, Viral myocarditis 💬1件: 222 💬
20 Bortezomib 💬1件: Bortezomib1件: Bortezomib1件: PSMB5 💬 8件: Alzheimer disease, Amyotrophic lateral sclerosis, Huntington disease, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Prion disease, Proteasome, Spinocerebellar ataxia 💬16件: 11, 13, 26, 28, 46, 49, 51, 61, 63, 66, 172, 222, 228, 256, 288, 331 💬
21 Cefadroxil 💬1件: Cefadroxil0件: ---
22 Cefadroxil 💬1件: Cefadroxil0件: ---
23 Cholesterol 💬1件: Cholesterol1件: Cholesterol--5件: 19, 90, 160, 222, 310 💬
24 Corticotropin 💬1件: Corticotropin3件: Acth; Adrenocorticotropic hormone; Corticotropin1件: MC2R 💬 6件: Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome, Hormone signaling, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬6件: 13, 78, 81, 84, 145, 222 💬
25 Corticotropin, repository 💬1件: Corticotropin3件: Acth; Adrenocorticotropic hormone; Corticotropin1件: MC2R 💬 6件: Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome, Hormone signaling, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬6件: 13, 78, 81, 84, 145, 222 💬
26 Cosyntropin 💬1件: Tetracosactide3件: Cosyntropin; Tetracosactide acetate; Tetracosactrin1件: MC2R 💬 6件: Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome, Hormone signaling, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬4件: 78, 83, 113, 145 💬
27 Creatinine 💬1件: Creatinine1件: Creatinine--6件: 2, 46, 60, 66, 70, 222 💬
28 Cyclophosphamide 💬1件: Cyclophosphamide5件: Ciclofosfamida; Ciclofosfamide; Cyclophosphamid; Cyclophosphamide; Cyclophosphamide monohydrate--46件: 11, 13, 14, 16, 19, 20, 26, 28, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 56, 60, 62, 65, 66, 84, 93, 96, 162, 164, 172, 205, 220, 221, 222, 224, 256, 265, 274, 283, 284, 285, 288, 326, 331 💬
29 Cyclophosphamide 💬1件: Cyclophosphamide5件: Ciclofosfamida; Ciclofosfamide; Cyclophosphamid; Cyclophosphamide; Cyclophosphamide monohydrate--46件: 11, 13, 14, 16, 19, 20, 26, 28, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 56, 60, 62, 65, 66, 84, 93, 96, 162, 164, 172, 205, 220, 221, 222, 224, 256, 265, 274, 283, 284, 285, 288, 326, 331 💬
30 Cyclosporine 💬1件: Cyclosporine6件: Ciclosporin; Ciclosporina; Ciclosporine; Cyclosporin; Cyclosporin A; Cyclosporine5件: PPP3C,
PPP3C,
PPP3C,
PPP3R,
PPP3R 💬 		33件: Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬37件: 11, 26, 28, 40, 41, 42, 45, 46, 49, 50, 53, 54, 55, 56, 60, 61, 62, 63, 64, 65, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 269, 274, 283, 284, 285, 302, 326 💬
31 Dalteparin sodium 💬1件: Dalteparin1件: Dalteparin1件: SERPINC1 💬 1件: Complement and coagulation cascades 💬1件: 222 💬
32 Danicopan 💬1件: Danicopan2件: ACH-0144471; Danicopan1件: CFD 💬 3件: Complement and coagulation cascades, Coronavirus disease - COVID-19, Staphylococcus aureus infection 💬2件: 62, 222 💬
33 Dapagliflozin 💬1件: Dapagliflozin1件: Dapagliflozin--10件: 6, 28, 49, 66, 67, 86, 88, 215, 218, 222 💬
34 Dexamethasone 💬1件: Dexamethasone2件: Dexamethasone; Dexamethasone sodium phosphate1件: NR3C1 💬 1件: Neuroactive ligand-receptor interaction 💬23件: 13, 14, 16, 19, 28, 35, 63, 64, 65, 70, 74, 75, 81, 84, 90, 96, 97, 222, 235, 257, 296, 299, 331 💬
35 Dexamethasone phosphate 💬1件: Dexamethasone2件: Dexamethasone; Dexamethasone sodium phosphate1件: NR3C1 💬 1件: Neuroactive ligand-receptor interaction 💬23件: 13, 14, 16, 19, 28, 35, 63, 64, 65, 70, 74, 75, 81, 84, 90, 96, 97, 222, 235, 257, 296, 299, 331 💬
36 Dexamethasone sodium phosphate 💬1件: Dexamethasone2件: Dexamethasone; Dexamethasone sodium phosphate1件: NR3C1 💬 1件: Neuroactive ligand-receptor interaction 💬23件: 13, 14, 16, 19, 28, 35, 63, 64, 65, 70, 74, 75, 81, 84, 90, 96, 97, 222, 235, 257, 296, 299, 331 💬
37 Diphenhydramine 💬1件: Diphenhydramine2件: Diphenhydramine; Diphenhydramine hydrochloride1件: HRH1 💬 4件: Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction 💬11件: 11, 13, 19, 49, 51, 70, 86, 96, 222, 256, 300 💬
38 Diphenhydramine citrate 💬1件: Diphenhydramine2件: Diphenhydramine; Diphenhydramine hydrochloride1件: HRH1 💬 4件: Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction 💬11件: 11, 13, 19, 49, 51, 70, 86, 96, 222, 256, 300 💬
39 Diphenhydramine hydrochloride 💬1件: Diphenhydramine2件: Diphenhydramine; Diphenhydramine hydrochloride1件: HRH1 💬 4件: Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction 💬11件: 11, 13, 19, 49, 51, 70, 86, 96, 222, 256, 300 💬
40 Diphenhydramine salicylate 💬1件: Diphenhydramine2件: Diphenhydramine; Diphenhydramine hydrochloride1件: HRH1 💬 4件: Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction 💬11件: 11, 13, 19, 49, 51, 70, 86, 96, 222, 256, 300 💬
41 Divalproex sodium 💬1件: Valproic acid3件: Valproate; Valproate sodium; Valproic acid7件: ABAT,
ALDH5A1,
CACNA1G,
CACNA1H,
CACNA1I,
E4.1.1.15,
E4.1.1.15 💬 		16件: Alanine, aspartate and glutamate metabolism, Aldosterone synthesis and secretion, Butanoate metabolism, Calcium signaling pathway, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, GABAergic synapse, GnRH secretion, MAPK signaling pathway, Propanoate metabolism, Taurine and hypotaurine metabolism, Type I diabetes mellitus, Type II diabetes mellitus, Valine, leucine and isoleucine degradation, beta-Alanine metabolism 💬9件: 3, 5, 26, 34, 65, 89, 90, 222, 331 💬
42 Eculizumab 💬1件: Eculizumab1件: Eculizumab1件: C5 💬 11件: Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Regulation of actin cytoskeleton, Staphylococcus aureus infection, Systemic lupus erythematosus 💬8件: 11, 13, 14, 61, 62, 109, 221, 222 💬
43 Enalapril 💬1件: Enalapril2件: Enalapril; Enalapril maleate1件: ACE 💬 6件: Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬7件: 13, 46, 66, 113, 210, 222, 279 💬
44 Enalapril maleate 💬1件: Enalapril2件: Enalapril; Enalapril maleate1件: ACE 💬 6件: Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬7件: 13, 46, 66, 113, 210, 222, 279 💬
45 Evolocumab 💬1件: Evolocumab1件: Evolocumab1件: PCSK9 💬 1件: Cholesterol metabolism 💬2件: 79, 222 💬
46 Filgotinib 💬1件: Filgotinib2件: Filgotinib; Filgotinib maleate1件: JAK1 💬 27件: Coronavirus disease - COVID-19, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Measles, NOD-like receptor signaling pathway, Necroptosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬10件: 46, 53, 56, 96, 97, 107, 222, 271, 300, 331 💬
47 Filgotinib maleate 💬1件: Filgotinib2件: Filgotinib; Filgotinib maleate4件: JAK1,
JAK2,
JAK3,
TYK2 💬 		39件: AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease - COVID-19, Efferocytosis, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Hormone signaling, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Necroptosis, Non-small cell lung cancer, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Primary immunodeficiency, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬10件: 46, 53, 56, 96, 97, 107, 222, 271, 300, 331 💬
48 Finerenone 💬1件: Finerenone1件: Finerenone1件: NR3C2 💬 1件: Aldosterone-regulated sodium reabsorption 💬4件: 66, 218, 222, 224 💬
49 Fludarabine 💬1件: Fludarabine2件: Fludarabine; Fludarabine phosphate1件: RRM1 💬 4件: Drug metabolism - other enzymes, Glutathione metabolism, Purine metabolism, Pyrimidine metabolism 💬25件: 11, 13, 19, 28, 34, 35, 36, 44, 46, 49, 51, 60, 61, 62, 65, 85, 96, 107, 164, 222, 283, 284, 285, 286, 326 💬
50 Fludarabine phosphate 💬1件: Fludarabine2件: Fludarabine; Fludarabine phosphate1件: RRM1 💬 4件: Drug metabolism - other enzymes, Glutathione metabolism, Purine metabolism, Pyrimidine metabolism 💬25件: 11, 13, 19, 28, 34, 35, 36, 44, 46, 49, 51, 60, 61, 62, 65, 85, 96, 107, 164, 222, 283, 284, 285, 286, 326 💬
51 Fluvastatin 💬1件: Fluvastatin1件: Fluvastatin1件: HMGCR 💬 3件: AMPK signaling pathway, Bile secretion, Terpenoid backbone biosynthesis 💬2件: 79, 222 💬
52 Fluvastatin sodium 💬1件: Fluvastatin1件: Fluvastatin1件: HMGCR 💬 3件: AMPK signaling pathway, Bile secretion, Terpenoid backbone biosynthesis 💬2件: 79, 222 💬
53 Fosfomycin 💬1件: Fosfomycin1件: Fosfomycin--2件: 96, 97 💬
54 Fosfomycin sodium 💬1件: Fosfomycin1件: Fosfomycin--2件: 96, 97 💬
55 Fosfomycin tromethamine 💬1件: Fosfomycin1件: Fosfomycin--2件: 96, 97 💬
56 Fresolimumab 💬1件: Fresolimumab2件: Fresolimumab; GC10083件: TGFB1,
TGFB2,
TGFB3 💬 		36件: AGE-RAGE signaling pathway in diabetic complications, Amoebiasis, Cell cycle, Cellular senescence, Chagas disease, Chronic myeloid leukemia, Colorectal cancer, Cytokine-cytokine receptor interaction, Diabetic cardiomyopathy, Dilated cardiomyopathy, Efferocytosis, FoxO signaling pathway, Gastric cancer, Hepatitis B, Hepatocellular carcinoma, Hippo signaling pathway, Human T-cell leukemia virus 1 infection, Hypertrophic cardiomyopathy, Inflammatory bowel disease, Intestinal immune network for IgA production, Leishmaniasis, MAPK signaling pathway, Malaria, MicroRNAs in cancer, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pancreatic cancer, Pathways in cancer, Proteoglycans in cancer, Relaxin signaling pathway, Renal cell carcinoma, Rheumatoid arthritis, TGF-beta signaling pathway, Th17 cell differentiation, Toxoplasmosis, Tuberculosis 💬4件: 51, 85, 222, 274 💬
57 Frexalimab 💬1件: Frexalimab1件: Frexalimab1件: TNFSF5 💬 14件: Allograft rejection, Asthma, Autoimmune thyroid disease, Cell adhesion molecules, Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, Lipid and atherosclerosis, Malaria, NF-kappa B signaling pathway, Primary immunodeficiency, Systemic lupus erythematosus, T cell receptor signaling pathway, Toxoplasmosis, Viral myocarditis 💬2件: 13, 222 💬
58 Galactose 💬1件: Galactose1件: Galactose--2件: 171, 222 💬
59 Glutamine 💬1件: L-Glutamine2件: Glutamine; L-glutamine--10件: 87, 89, 96, 97, 113, 214, 215, 222, 245, 299 💬
60 Human serum albumin 💬1件: Albumin human3件: Albumin; Human albumin; Serum albumin--5件: 2, 11, 50, 222, 296 💬
61 Hydroxychloroquine 💬1件: Hydroxychloroquine2件: Hydroxychloroquine; Hydroxychloroquine sulfate--26件: 6, 13, 34, 41, 43, 44, 45, 46, 48, 49, 53, 56, 63, 66, 84, 96, 97, 107, 218, 222, 224, 234, 254, 271, 298, 299 💬
62 Hydroxychloroquine sulfate 💬1件: Hydroxychloroquine2件: Hydroxychloroquine; Hydroxychloroquine sulfate--26件: 6, 13, 34, 41, 43, 44, 45, 46, 48, 49, 53, 56, 63, 66, 84, 96, 97, 107, 218, 222, 224, 234, 254, 271, 298, 299 💬
63 Iptacopan 💬1件: Iptacopan1件: Iptacopan1件: CFB 💬 3件: Complement and coagulation cascades, Coronavirus disease - COVID-19, Staphylococcus aureus infection 💬6件: 11, 61, 62, 66, 109, 222 💬
64 Iptacopan hydrochloride 💬1件: Iptacopan1件: Iptacopan1件: CFB 💬 3件: Complement and coagulation cascades, Coronavirus disease - COVID-19, Staphylococcus aureus infection 💬6件: 11, 61, 62, 66, 109, 222 💬
65 Irbesartan 💬1件: Irbesartan1件: Irbesartan1件: AGTR1 💬 17件: AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Hormone signaling, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬4件: 66, 167, 168, 222 💬
66 Lanraplenib 💬1件: Lanraplenib1件: Lanraplenib--2件: 53, 222 💬
67 Lansoprazole 💬1件: Lansoprazole1件: Lansoprazole2件: ATP4A,
ATP4B 💬 		3件: Collecting duct acid secretion, Gastric acid secretion, Oxidative phosphorylation 💬4件: 71, 85, 166, 299 💬
68 Levamisole 💬1件: Levamisole2件: Levamisole; Levamisole hydrochloride--3件: 60, 61, 222 💬
69 Levamisole hydrochloride 💬1件: Levamisole2件: Levamisole; Levamisole hydrochloride--3件: 60, 61, 222 💬
70 Lisinopril 💬1件: Lisinopril1件: Lisinopril1件: ACE 💬 6件: Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬5件: 19, 46, 66, 67, 113 💬
71 Lisinopril 💬1件: Lisinopril1件: Lisinopril1件: ACE 💬 6件: Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬5件: 19, 46, 66, 67, 113 💬
72 Losartan 💬1件: Losartan2件: Losartan; Losartan potassium1件: AGTR1 💬 17件: AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Hormone signaling, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
73 Losartan potassium 💬1件: Losartan2件: Losartan; Losartan potassium1件: AGTR1 💬 17件: AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Hormone signaling, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
74 Losmapimod 💬1件: Losmapimod1件: Losmapimod4件: P38,
P38,
P38,
P38 💬 		62件: AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Alcoholic liver disease, Amyotrophic lateral sclerosis, C-type lectin receptor signaling pathway, Cellular senescence, Chagas disease, Chemical carcinogenesis - reactive oxygen species, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Dopaminergic synapse, Efferocytosis, Epithelial cell signaling in Helicobacter pylori infection, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, FoxO signaling pathway, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hepatitis B, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, IL-17 signaling pathway, Inflammatory mediator regulation of TRP channels, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Leukocyte transendothelial migration, Lipid and atherosclerosis, MAPK signaling pathway, NOD-like receptor signaling pathway, Neurotrophin signaling pathway, Neutrophil extracellular trap formation, Non-alcoholic fatty liver disease, Oocyte meiosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Platelet activation, Prion disease, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rap1 signaling pathway, Relaxin signaling pathway, Retrograde endocannabinoid signaling, Salmonella infection, Shigellosis, Signaling pathways regulating pluripotency of stem cells, Sphingolipid signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Thermogenesis, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, VEGF signaling pathway, Yersinia infection 💬2件: 113, 222 💬
75 Melphalan 💬1件: Melphalan2件: Melphalan; Melphalan hydrochloride--19件: 11, 13, 14, 19, 20, 28, 34, 46, 60, 62, 65, 96, 107, 164, 222, 234, 284, 285, 299 💬
76 Melphalan hydrochloride 💬1件: Melphalan2件: Melphalan; Melphalan hydrochloride--19件: 11, 13, 14, 19, 20, 28, 34, 46, 60, 62, 65, 96, 107, 164, 222, 234, 284, 285, 299 💬
77 Metformin 💬1件: Metformin3件: Metformin; Metformin hydrochloride; Metformina2件: PRKAA,
PRKAA 💬 		20件: AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬27件: 2, 6, 8, 13, 46, 49, 60, 65, 66, 67, 75, 77, 81, 84, 86, 97, 113, 127, 158, 206, 218, 225, 265, 285, 298, 299, 301 💬
78 Metformin hydrochloride 💬1件: Metformin3件: Metformin; Metformin hydrochloride; Metformina2件: PRKAA,
PRKAA 💬 		20件: AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬27件: 2, 6, 8, 13, 46, 49, 60, 65, 66, 67, 75, 77, 81, 84, 86, 97, 113, 127, 158, 206, 218, 225, 265, 285, 298, 299, 301 💬
79 Methylprednisolone 💬1件: Methylprednisolone3件: Methylprednisolon; Methylprednisolone; Methylprednisolone acetate1件: NR3C1 💬 1件: Neuroactive ligand-receptor interaction 💬45件: 2, 6, 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 96, 97, 127, 162, 164, 222, 224, 271, 283, 284, 285, 296, 300 💬
80 Methylprednisolone acetate 💬1件: Methylprednisolone3件: Methylprednisolon; Methylprednisolone; Methylprednisolone acetate1件: NR3C1 💬 1件: Neuroactive ligand-receptor interaction 💬45件: 2, 6, 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 96, 97, 127, 162, 164, 222, 224, 271, 283, 284, 285, 296, 300 💬
81 Mizoribine 💬1件: Mizoribine1件: Mizoribine2件: IMPDH,
IMPDH 💬 		2件: Drug metabolism - other enzymes, Purine metabolism 💬8件: 46, 49, 51, 53, 66, 94, 222, 224 💬
82 Monomethyl fumarate 💬1件: Monomethyl fumarate1件: Monomethyl fumarate--1件: 13 💬
83 Mycophenolate mofetil 💬1件: Mycophenolate mofetil1件: Mycophenolate mofetil2件: IMPDH,
IMPDH 💬 		2件: Drug metabolism - other enzymes, Purine metabolism 💬32件: 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 46, 49, 51, 53, 60, 62, 63, 65, 66, 93, 95, 96, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬
84 Mycophenolate mofetil hydrochloride 💬1件: Mycophenolate mofetil1件: Mycophenolate mofetil2件: IMPDH,
IMPDH 💬 		2件: Drug metabolism - other enzymes, Purine metabolism 💬32件: 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 46, 49, 51, 53, 60, 62, 63, 65, 66, 93, 95, 96, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬
85 Mycophenolate sodium 💬1件: Mycophenolic acid5件: Acido micofenolico; Micofenolico acido; Mycophenolate; Mycophenolate sodium; Mycophenolic acid2件: IMPDH,
IMPDH 💬 		2件: Drug metabolism - other enzymes, Purine metabolism 💬12件: 11, 43, 49, 51, 53, 60, 66, 84, 96, 162, 222, 228 💬
86 Mycophenolic acid 💬1件: Mycophenolic acid5件: Acido micofenolico; Micofenolico acido; Mycophenolate; Mycophenolate sodium; Mycophenolic acid2件: IMPDH,
IMPDH 💬 		2件: Drug metabolism - other enzymes, Purine metabolism 💬12件: 11, 43, 49, 51, 53, 60, 66, 84, 96, 162, 222, 228 💬
87 Narsoplimab 💬1件: Narsoplimab1件: Narsoplimab1件: MASP2 💬 3件: Complement and coagulation cascades, Coronavirus disease - COVID-19, Staphylococcus aureus infection 💬2件: 66, 222 💬
88 Obinutuzumab 💬1件: Obinutuzumab1件: Obinutuzumab1件: MS4A1 💬 1件: Hematopoietic cell lineage 💬5件: 43, 44, 49, 63, 222 💬
89 Panax notoginseng root 💬1件: Panax notoginseng root1件: Sanqi--2件: 222, 224 💬
90 Pegcetacoplan 💬1件: Pegcetacoplan1件: Pegcetacoplan1件: C3 💬 17件: Alcoholic liver disease, Chagas disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Legionellosis, Leishmaniasis, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Phagosome, Shigellosis, Staphylococcus aureus infection, Systemic lupus erythematosus, Tuberculosis, Viral carcinogenesis 💬4件: 2, 61, 62, 222 💬
91 Peginterferon alfa-2a 💬1件: Peginterferon alfa-2a0件: 2件: IFNAR1,
IFNAR2 💬 		18件: Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Measles, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Osteoclast differentiation, PI3K-Akt signaling pathway, Pathways in cancer, Toll-like receptor signaling pathway 💬-
92 Pentoxifylline 💬1件: Pentoxifylline1件: Pentoxifylline--11件: 26, 56, 84, 93, 96, 97, 113, 220, 222, 296, 298 💬
93 Perindopril 💬1件: Perindopril2件: Perindopril; Perindopril arginine1件: ACE 💬 6件: Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬4件: 58, 113, 167, 222 💬
94 Perindopril arginine 💬1件: Perindopril2件: Perindopril; Perindopril arginine1件: ACE 💬 6件: Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬4件: 58, 113, 167, 222 💬
95 Perindopril erbumine 💬1件: Perindopril2件: Perindopril; Perindopril arginine1件: ACE 💬 6件: Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬4件: 58, 113, 167, 222 💬
96 Pirfenidone 💬1件: Pirfenidone1件: Pirfenidone6件: CCL2,
IL10,
IL1A,
IL1B,
IL6,
TNF 💬 		83件: AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antigen processing and presentation, Apoptosis, Asthma, Autoimmune thyroid disease, C-type lectin receptor signaling pathway, Cellular senescence, Chagas disease, Chemokine signaling pathway, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, Dilated cardiomyopathy, Efferocytosis, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Graft-versus-host disease, HIF-1 signaling pathway, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Inflammatory mediator regulation of TRP channels, Influenza A, Insulin resistance, Intestinal immune network for IgA production, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, Measles, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Staphylococcus aureus infection, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Transcriptional misregulation in cancer, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
97 Povetacicept 💬1件: Povetacicept1件: Povetacicept1件: TNFRSF13B 💬 3件: Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, Primary immunodeficiency 💬3件: 61, 63, 222 💬
98 Prednisolone 💬1件: Prednisolone3件: Prednisolona; Prednisolone; Prednisolonum1件: NR3C1 💬 1件: Neuroactive ligand-receptor interaction 💬39件: 3, 11, 13, 14, 18, 25, 26, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 54, 56, 60, 63, 64, 66, 81, 84, 85, 96, 97, 113, 145, 162, 222, 251, 269, 271, 296, 299, 300 💬
99 Prednisolone acetate 💬1件: Prednisolone acetate1件: Prednisolone acetate1件: NR3C1 💬 1件: Neuroactive ligand-receptor interaction 💬1件: 222 💬
100 Prednisone 💬1件: Prednisone2件: Prednisona; Prednisone1件: NR3C1 💬 1件: Neuroactive ligand-receptor interaction 💬54件: 2, 11, 13, 14, 18, 19, 26, 28, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 60, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 90, 93, 95, 96, 97, 113, 145, 162, 164, 205, 222, 224, 228, 251, 269, 283, 285, 288, 299, 300, 303, 307, 331 💬
101 Prednisone acetate 💬1件: Prednisone acetate2件: Cortancyl; Prednisone acetate1件: NR3C1 💬 1件: Neuroactive ligand-receptor interaction 💬7件: 35, 41, 46, 49, 63, 162, 222 💬
102 Propagermanium 💬1件: Propagermanium1件: Repagermanium--1件: 222 💬
103 Rilzabrutinib 💬1件: Rilzabrutinib1件: Rilzabrutinib1件: BTK 💬 7件: B cell receptor signaling pathway, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, NF-kappa B signaling pathway, Osteoclast differentiation, Platelet activation, Primary immunodeficiency 💬5件: 35, 61, 63, 222, 300 💬
104 Rituximab 💬1件: Rituximab1件: Rituximab1件: MS4A1 💬 1件: Hematopoietic cell lineage 💬52件: 11, 13, 14, 19, 26, 34, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 55, 56, 60, 61, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 162, 172, 220, 222, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331 💬
105 Rosiglitazone 💬1件: Rosiglitazone2件: Rosiglitazone; Rosiglitazone maleate1件: NR1C3 💬 12件: AMPK signaling pathway, Efferocytosis, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬6件: 46, 75, 77, 97, 222, 265 💬
106 Rosiglitazone maleate 💬1件: Rosiglitazone2件: Rosiglitazone; Rosiglitazone maleate1件: NR1C3 💬 12件: AMPK signaling pathway, Efferocytosis, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬6件: 46, 75, 77, 97, 222, 265 💬
107 Sacubitril 💬1件: Sacubitril1件: Sacubitril1件: MME 💬 4件: Alzheimer disease, Hematopoietic cell lineage, Protein digestion and absorption, Renin-angiotensin system 💬2件: 210, 222 💬
108 Sirolimus 💬1件: Sirolimus2件: Rapamycin; Sirolimus1件: MTOR 💬 49件: AMPK signaling pathway, Acute myeloid leukemia, Adipocytokine signaling pathway, Alzheimer disease, Amyotrophic lateral sclerosis, Apelin signaling pathway, Autophagy - animal, Autophagy - other, Breast cancer, Cellular senescence, Central carbon metabolism in cancer, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Diabetic cardiomyopathy, ErbB signaling pathway, Gastric cancer, Glioma, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatocellular carcinoma, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Huntington disease, Insulin resistance, Insulin signaling pathway, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Longevity regulating pathway, Longevity regulating pathway - multiple species, MicroRNAs in cancer, Neutrophil extracellular trap formation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Shigellosis, Spinocerebellar ataxia, Th17 cell differentiation, Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus, mTOR signaling pathway 💬44件: 2, 6, 13, 15, 19, 21, 34, 35, 36, 46, 48, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 97, 98, 137, 157, 158, 192, 193, 222, 227, 256, 277, 278, 279, 280, 281, 283, 285, 300, 331 💬
109 Sodium butyrate 💬1件: Butyric Acid4件: Butanoic acid; Butyrate; Butyric acid; Sodium butyrate--3件: 46, 97, 222 💬
110 Sparsentan 💬1件: Sparsentan1件: Sparsentan2件: AGTR1,
EDNRA 💬 		18件: AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Hormone signaling, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬3件: 66, 218, 222 💬
111 Sulfuric acid 💬1件: Sulfate ion1件: Sulfate--6件: 2, 3, 11, 49, 222, 224 💬
112 Tacrolimus 💬1件: Tacrolimus1件: Tacrolimus5件: PPP3C,
PPP3C,
PPP3C,
PPP3R,
PPP3R 💬 		33件: Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬31件: 2, 6, 11, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 234, 283, 284, 285, 286 💬
113 Tacrolimus 💬1件: Tacrolimus1件: Tacrolimus5件: PPP3C,
PPP3C,
PPP3C,
PPP3R,
PPP3R 💬 		33件: Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬31件: 2, 6, 11, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 234, 283, 284, 285, 286 💬
114 Tetracosactide acetate 💬1件: Tetracosactide3件: Cosyntropin; Tetracosactide acetate; Tetracosactrin1件: MC2R 💬 6件: Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome, Hormone signaling, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬4件: 78, 83, 113, 145 💬
115 Valproate sodium 💬1件: Valproic acid3件: Valproate; Valproate sodium; Valproic acid7件: ABAT,
ALDH5A1,
CACNA1G,
CACNA1H,
CACNA1I,
E4.1.1.15,
E4.1.1.15 💬 		16件: Alanine, aspartate and glutamate metabolism, Aldosterone synthesis and secretion, Butanoate metabolism, Calcium signaling pathway, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, GABAergic synapse, GnRH secretion, MAPK signaling pathway, Propanoate metabolism, Taurine and hypotaurine metabolism, Type I diabetes mellitus, Type II diabetes mellitus, Valine, leucine and isoleucine degradation, beta-Alanine metabolism 💬9件: 3, 5, 26, 34, 65, 89, 90, 222, 331 💬
116 Valproic acid 💬1件: Valproic acid3件: Valproate; Valproate sodium; Valproic acid7件: ABAT,
ALDH5A1,
CACNA1G,
CACNA1H,
CACNA1I,
E4.1.1.15,
E4.1.1.15 💬 		16件: Alanine, aspartate and glutamate metabolism, Aldosterone synthesis and secretion, Butanoate metabolism, Calcium signaling pathway, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, GABAergic synapse, GnRH secretion, MAPK signaling pathway, Propanoate metabolism, Taurine and hypotaurine metabolism, Type I diabetes mellitus, Type II diabetes mellitus, Valine, leucine and isoleucine degradation, beta-Alanine metabolism 💬9件: 3, 5, 26, 34, 65, 89, 90, 222, 331 💬
117 Valsartan 💬1件: Valsartan1件: Valsartan1件: AGTR1 💬 17件: AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Hormone signaling, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬7件: 57, 58, 66, 75, 210, 222, 224 💬
118 Voclosporin 💬1件: Voclosporin1件: Voclosporin5件: PPP3C,
PPP3C,
PPP3C,
PPP3R,
PPP3R 💬 		33件: Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬2件: 49, 222 💬
119 Zanubrutinib 💬1件: Zanubrutinib1件: Zanubrutinib1件: BTK 💬 7件: B cell receptor signaling pathway, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, NF-kappa B signaling pathway, Osteoclast differentiation, Platelet activation, Primary immunodeficiency 💬5件: 13, 61, 63, 222, 331 💬