Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank 薬物名（臨床試験情報から抽出） KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
1 Abatacept 1件: Abatacept1件: Abatacept 💬 2件: CD80,
CD86 💬 		14件: Allograft rejection, Autoimmune thyroid disease, Cell adhesion molecule (CAM) interaction, Graft-versus-host disease, IgSF CAM signaling, Intestinal immune network for IgA production, Kaposi sarcoma-associated herpesvirus infection, Rheumatoid arthritis, Systemic lupus erythematosus, Toll-like receptor signaling pathway, Transcriptional misregulation in cancer, Type I diabetes mellitus, Viral myocarditis, Virion - Adenovirus 💬28件: 2, 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 223, 271, 284, 285, 300 💬
2 Acetaminophen 2件: Acetaminophen; PARACETAMOL1件: Acetaminophen 💬 2件: PTGS1,
PTGS2 💬 		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Efferocytosis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬19件: 11, 13, 19, 34, 35, 46, 49, 51, 63, 70, 77, 86, 96, 222, 231, 256, 271, 300, 337 💬
3 Acetate 1件: Acetate---52件: 1, 2, 6, 10, 11, 13, 22, 35, 40, 46, 49, 51, 60, 63, 64, 65, 66, 67, 70, 71, 73, 75, 76, 77, 78, 79, 81, 83, 85, 86, 88, 89, 90, 96, 97, 113, 145, 156, 158, 162, 171, 206, 222, 223, 224, 225, 227, 235, 251, 265, 298, 299 💬
4 Acetazolamide 1件: Acetazolamide2件: Acetazolamide ,
Acetazolamide sodium 💬 		13件: CA1,
CA12,
CA13,
CA14,
CA2,
CA3,
CA4,
CA5A,
CA5B,
CA6,
CA7,
CA8,
CA9 💬 		6件: Bile secretion, Collecting duct acid secretion, Gastric acid secretion, Nitrogen metabolism, Pancreatic secretion, Proximal tubule bicarbonate reclamation 💬8件: 13, 67, 90, 115, 155, 222, 225, 230 💬
5 Adalimumab 1件: ADALIMUMAB1件: Adalimumab 💬 1件: TNF 💬 66件: AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬22件: 19, 37, 38, 40, 41, 46, 55, 56, 84, 90, 96, 97, 107, 151, 160, 162, 164, 222, 226, 269, 270, 271 💬
6 Aldosterone 1件: Aldosterone1件: Aldosterone 💬 1件: NR3C2 💬 1件: Aldosterone-regulated sodium reabsorption 💬3件: 57, 75, 222 💬
7 Alfacalcidol 1件: ALFACALCIDOL1件: Alfacalcidol 💬 1件: VDR 💬 5件: Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬10件: 41, 46, 49, 50, 96, 107, 222, 223, 235, 238 💬
8 Aliskiren 1件: Aliskiren2件: Aliskiren ,
Aliskiren fumarate 💬 		1件: REN 💬 3件: Diabetic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬4件: 66, 167, 222, 223 💬
9 Ambrisentan 1件: Ambrisentan1件: Ambrisentan 💬 1件: EDNRA 💬 7件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Pathways in cancer, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬10件: 51, 66, 84, 85, 86, 88, 210, 211, 218, 222 💬
10 Amiloride 2件: Amiloride; Amiloride Hydrochloride2件: Amiloride hydrochloride ,
Amiloride 💬 		3件: SCNN1A,
SCNN1B,
SCNN1G 💬 		2件: Aldosterone-regulated sodium reabsorption, Taste transduction 💬5件: 13, 67, 222, 225, 299 💬
11 Amlodipine 1件: Amlodipine4件: Amlodipine besylate ,
Amlodipine maleate ,
Amlodipine ,
Amlodipine benzoate 💬 		4件: CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S 💬 		37件: Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬6件: 51, 67, 79, 113, 222, 298 💬
12 Amoxicillin 2件: Amoxicilina; Amoxicillin3件: Amoxicillin ,
Amoxicillin sodium ,
Amoxicillin 💬 		--9件: 6, 46, 63, 94, 96, 97, 222, 223, 299 💬
13 Angiotensin II 1件: Angiotensin II3件: Angiotensin II ,
Angiotensin II ,
Angiotensin II acetate 💬 		2件: AGTR1,
AGTR2 💬 		17件: AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Hormone signaling, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬2件: 66, 222 💬
14 Anti-CD19 CAR-T cells 2件: Anti-CD19 CAR-T cells; CD19 CAR-T cells---6件: 46, 49, 50, 51, 53, 222 💬
15 Apixaban 1件: Apixaban1件: Apixaban 💬 1件: F10 💬 1件: Complement and coagulation cascades 💬6件: 48, 96, 97, 222, 223, 279 💬
16 Atacicept 2件: ATACICEPT; TACI-Fc51件: Atacicept 💬 2件: TNFSF13,
TNFSF13B 💬 		4件: Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis 💬5件: 13, 46, 49, 66, 222 💬
17 Atorvastatin 3件: Atorvastatin; ATORVASTATIN CALCIUM; Atorvastatina2件: Atorvastatin calcium ,
Atorvastatin 💬 		1件: HMGCR 💬 3件: AMPK signaling pathway, Bile secretion, Terpenoid backbone biosynthesis 💬21件: 13, 22, 46, 49, 51, 58, 63, 67, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 297, 299 💬
18 Atrasentan 1件: ATRASENTAN1件: Atrasentan hydrochloride 💬 1件: EDNRA 💬 7件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Pathways in cancer, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬3件: 66, 218, 222 💬
19 Azithromycin 4件: Azithromycin; AZITHROMYCIN DIHYDRATE; AZITHROMYCIN MONOHYDRATE; AZITHROMYCINE3件: Azithromycin hydrate ,
Azithromycin ,
Azithromycin 💬 		--8件: 13, 84, 85, 96, 222, 228, 299, 340 💬
20 Bardoxolone 1件: Bardoxolone1件: Bardoxolone 💬 --7件: 66, 67, 84, 85, 86, 218, 222 💬
21 Bardoxolone methyl 1件: BARDOXOLONE METHYL1件: Bardoxolone methyl 💬 --7件: 66, 67, 84, 85, 86, 218, 222 💬
22 Basiliximab 1件: Basiliximab1件: Basiliximab 💬 1件: IL2RA 💬 11件: Cytokine-cytokine receptor interaction, Endocytosis, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, JAK-STAT signaling pathway, Measles, PI3K-Akt signaling pathway, Pathways in cancer, Th1 and Th2 cell differentiation, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬5件: 2, 50, 97, 222, 228 💬
23 Belimumab 1件: Belimumab1件: Belimumab 💬 1件: TNFSF13B 💬 4件: Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis 💬17件: 11, 13, 43, 44, 46, 48, 49, 50, 51, 53, 63, 66, 95, 222, 223, 296, 300 💬
24 Benazepril 1件: Benazepril2件: Benazepril hydrochloride ,
Benazepril 💬 		1件: ACE 💬 6件: Chagas disease, Coronavirus disease, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬5件: 49, 57, 218, 222, 224 💬
25 Bleselumab 1件: Bleselumab1件: Bleselumab 💬 1件: CD40 💬 17件: Allograft rejection, Asthma, Autoimmune thyroid disease, Cell adhesion molecule (CAM) interaction, Cytokine-cytokine receptor interaction, Epstein-Barr virus infection, Human T-cell leukemia virus 1 infection, Intestinal immune network for IgA production, Lipid and atherosclerosis, Malaria, NF-kappa B signaling pathway, Primary immunodeficiency, Systemic lupus erythematosus, Toll-like receptor signaling pathway, Toxoplasmosis, Transcriptional misregulation in cancer, Viral myocarditis 💬1件: 222 💬
26 Blinatumomab 1件: Blinatumomab1件: Blinatumomab 💬 4件: CD19,
CD3D,
CD3E,
CD3G 💬 		13件: B cell receptor signaling pathway, Chagas disease, Epstein-Barr virus infection, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, Human immunodeficiency virus 1 infection, Measles, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Primary immunodeficiency, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation 💬4件: 11, 46, 49, 222 💬
27 Bortezomib 1件: Bortezomib1件: Bortezomib 💬 1件: PSMB5 💬 8件: Alzheimer disease, Amyotrophic lateral sclerosis, Huntington disease, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Prion disease, Proteasome, Spinocerebellar ataxia 💬19件: 11, 13, 26, 28, 46, 49, 51, 61, 63, 64, 66, 172, 222, 223, 228, 256, 283, 288, 331 💬
28 Budoprutug 1件: Budoprutug---3件: 49, 63, 222 💬
29 Butyric Acid 3件: Butyrate; Butyric Acid; Sodium Butyrate1件: Sodium butyrate 💬 --3件: 46, 156, 222 💬
30 Calcium 1件: Calcium---39件: 2, 3, 6, 13, 15, 19, 46, 48, 49, 51, 53, 56, 62, 67, 68, 71, 74, 75, 79, 84, 90, 93, 94, 95, 96, 97, 156, 186, 214, 215, 222, 224, 235, 256, 265, 271, 274, 298, 299 💬
31 Candesartan 1件: Candesartan1件: Candesartan 💬 1件: AGTR1 💬 17件: AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Hormone signaling, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬4件: 57, 58, 67, 222 💬
32 Chlorambucil 1件: Chlorambucil1件: Chlorambucil 💬 --2件: 222, 223 💬
33 Cholecalciferol 4件: Cholecalciferol; Colecalciferol; Vitamin D-3; Vitamin D31件: Cholecalciferol 💬 1件: VDR 💬 5件: Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬10件: 13, 19, 34, 46, 49, 96, 97, 222, 298, 299 💬
34 Cholesterol 1件: Cholesterol1件: Cholesterol 💬 --10件: 8, 19, 71, 79, 90, 160, 222, 259, 261, 310 💬
35 Clarithromycin 1件: Clarithromycin1件: Clarithromycin 💬 --10件: 6, 46, 63, 84, 96, 97, 222, 223, 228, 299 💬
36 Clopidogrel 1件: Clopidogrel4件: Clopidogrel bisulfate ,
Clopidogrel ,
Clopidogrel hydrochloride ,
Clopidogrel besilate 💬 		1件: P2RY12 💬 3件: Efferocytosis, Neuroactive ligand signaling, Platelet activation 💬7件: 40, 49, 51, 62, 71, 86, 222 💬
37 Corticotropin 3件: ACTH; Adrenocorticotropic Hormone; Corticotropin2件: Corticotropin ,
Corticotropin, repository 💬 		1件: MC2R 💬 6件: Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome, Hormone signaling, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬10件: 2, 13, 46, 75, 78, 81, 84, 145, 205, 222 💬
38 Creatinine 1件: Creatinine1件: Creatinine 💬 --9件: 2, 46, 49, 60, 66, 70, 96, 97, 222 💬
39 CXA-10 1件: CXA-10---2件: 86, 222 💬
40 Cyclophosphamide 5件: Ciclofosfamida; CICLOFOSFAMIDE; Cyclophosphamid; Cyclophosphamide; CYCLOPHOSPHAMIDE MONOHYDRATE2件: Cyclophosphamide ,
Cyclophosphamide 💬 		--50件: 11, 13, 14, 16, 19, 20, 26, 28, 34, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 56, 60, 61, 62, 63, 65, 66, 84, 93, 96, 162, 164, 172, 205, 221, 222, 223, 224, 256, 265, 274, 283, 284, 285, 288, 326, 331 💬
41 Cyclosporine 7件: CICLOSPORIN; Ciclosporina; Ciclosporine; Cyclosporin; Cyclosporin A; Cyclosporine; Cyclosporine A1件: Cyclosporine 💬 5件: PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬 		33件: Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬39件: 11, 14, 19, 20, 28, 36, 40, 41, 42, 45, 46, 49, 50, 53, 56, 58, 60, 61, 62, 63, 64, 65, 67, 90, 95, 97, 107, 118, 162, 164, 222, 223, 226, 228, 234, 283, 284, 285, 302 💬
42 Dalteparin 2件: Dalteparin; Dalteparin Sodium1件: Dalteparin sodium 💬 1件: SERPINC1 💬 1件: Complement and coagulation cascades 💬3件: 222, 223, 327 💬
43 Dapagliflozin 1件: Dapagliflozin1件: Dapagliflozin 💬 --16件: 6, 19, 28, 40, 41, 49, 57, 66, 67, 86, 88, 97, 210, 215, 218, 222 💬
44 Daratumumab 1件: DARATUMUMAB1件: Daratumumab 💬 1件: CD38 💬 6件: Calcium signaling pathway, Hematopoietic cell lineage, Nicotinate and nicotinamide metabolism, Oxytocin signaling pathway, Pancreatic secretion, Salivary secretion 💬13件: 13, 16, 28, 39, 46, 48, 49, 60, 63, 222, 223, 288, 331 💬
45 Dexamethasone 4件: Dexametasone; Dexamethason; Dexamethasone; DEXAMETHASONE SODIUM PHOSPHATE3件: Dexamethasone ,
Dexamethasone sodium phosphate ,
Dexamethasone phosphate 💬 		1件: NR3C1 💬 1件: Neuroactive ligand-receptor interaction 💬29件: 13, 14, 16, 19, 28, 35, 46, 53, 63, 64, 65, 70, 71, 74, 75, 81, 84, 90, 96, 97, 162, 222, 223, 235, 257, 283, 296, 299, 331 💬
46 Diphenhydramine 2件: Diphenhydramine; Diphenhydramine hydrochloride4件: Diphenhydramine ,
Diphenhydramine hydrochloride ,
Diphenhydramine salicylate ,
Diphenhydramine citrate 💬 		1件: HRH1 💬 4件: Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction 💬12件: 11, 13, 19, 49, 51, 63, 70, 86, 96, 222, 256, 300 💬
47 Dipyridamole 1件: Dipyridamole1件: Dipyridamole 💬 2件: PDE4A,
PDE5A 💬 		5件: Morphine addiction, Parathyroid hormone synthesis, secretion and action, Purine metabolism, cAMP signaling pathway, cGMP-PKG signaling pathway 💬7件: 46, 49, 51, 66, 96, 222, 224 💬
48 Dupilumab 1件: Dupilumab1件: Dupilumab 💬 1件: IL4R 💬 8件: Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, Inflammatory bowel disease, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer, Th1 and Th2 cell differentiation, Th17 cell differentiation 💬8件: 51, 97, 98, 160, 162, 222, 300, 306 💬
49 Edoxaban 1件: Edoxaban3件: Edoxaban tosilate hydrate ,
Edoxaban ,
Edoxaban tosylate 💬 		1件: F10 💬 1件: Complement and coagulation cascades 💬4件: 46, 71, 88, 222 💬
50 Empagliflozin 1件: Empagliflozin1件: Empagliflozin 💬 --17件: 28, 46, 57, 58, 65, 67, 72, 77, 86, 96, 97, 113, 222, 223, 257, 298, 299 💬
51 Enalapril 2件: Enalapril; Enalapril Maleate2件: Enalapril maleate ,
Enalapril 💬 		1件: ACE 💬 6件: Chagas disease, Coronavirus disease, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬10件: 13, 19, 46, 57, 66, 113, 210, 222, 223, 279 💬
52 Enoxaparin 2件: Enoxaparin; Enoxaparin Sodium2件: Enoxaparin sodium ,
Adomiparin 💬 		1件: SERPINC1 💬 1件: Complement and coagulation cascades 💬6件: 46, 48, 71, 222, 223, 327 💬
53 Entecavir 1件: Entecavir2件: Entecavir ,
Entecavir 💬 		--8件: 46, 56, 96, 97, 107, 222, 223, 271 💬
54 Evolocumab 1件: EVOLOCUMAB1件: Evolocumab 💬 1件: PCSK9 💬 1件: Cholesterol metabolism 💬2件: 79, 222 💬
55 Fecal microbiota 3件: Fecal Microbial Transplantation; Fecal microbiota; Fecal Microbiota Transplantation---14件: 2, 6, 13, 49, 63, 66, 93, 94, 96, 97, 99, 222, 271, 298 💬
56 Felzartamab 1件: Felzartamab---2件: 66, 222 💬
57 Filgotinib 2件: Filgotinib; Filgotinib Maleate2件: Filgotinib ,
Filgotinib maleate 💬 		4件: JAK1,
JAK2,
JAK3,
TYK2 💬 		39件: AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease, Efferocytosis, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Hormone signaling, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Necroptosis, Non-small cell lung cancer, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Primary immunodeficiency, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬10件: 46, 53, 56, 96, 97, 107, 222, 271, 300, 331 💬
58 Finerenone 1件: Finerenone1件: Finerenone 💬 1件: NR3C2 💬 1件: Aldosterone-regulated sodium reabsorption 💬5件: 66, 218, 222, 223, 224 💬
59 Fludarabine 3件: FLUDARABINA; Fludarabine; Fludarabine Phosphate2件: Fludarabine phosphate ,
Fludarabine 💬 		1件: RRM1 💬 4件: Drug metabolism - other enzymes, Glutathione metabolism, Purine metabolism, Pyrimidine metabolism 💬30件: 11, 13, 14, 16, 19, 28, 34, 35, 36, 44, 46, 49, 50, 51, 60, 61, 62, 63, 65, 85, 96, 107, 164, 222, 223, 283, 284, 285, 286, 326 💬
60 Fluvastatin 1件: Fluvastatin2件: Fluvastatin sodium ,
Fluvastatin 💬 		1件: HMGCR 💬 3件: AMPK signaling pathway, Bile secretion, Terpenoid backbone biosynthesis 💬4件: 48, 79, 218, 222 💬
61 Fresolimumab 2件: Fresolimumab; GC10081件: Fresolimumab 💬 3件: TGFB1,
TGFB2,
TGFB3 💬 		37件: AGE-RAGE signaling pathway in diabetic complications, Amoebiasis, Cell cycle, Cellular senescence, Chagas disease, Chronic myeloid leukemia, Colorectal cancer, Cytokine-cytokine receptor interaction, Diabetic cardiomyopathy, Dilated cardiomyopathy, Efferocytosis, FoxO signaling pathway, Gastric cancer, Hepatitis B, Hepatocellular carcinoma, Hippo signaling pathway, Human T-cell leukemia virus 1 infection, Hypertrophic cardiomyopathy, Inflammatory bowel disease, Integrin signaling, Intestinal immune network for IgA production, Leishmaniasis, MAPK signaling pathway, Malaria, MicroRNAs in cancer, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pancreatic cancer, Pathways in cancer, Proteoglycans in cancer, Relaxin signaling pathway, Renal cell carcinoma, Rheumatoid arthritis, TGF-beta signaling pathway, Th17 cell differentiation, Toxoplasmosis, Tuberculosis 💬3件: 51, 222, 274 💬
62 Frexalimab 1件: Frexalimab1件: Frexalimab 💬 1件: CD40LG 💬 14件: Allograft rejection, Asthma, Autoimmune thyroid disease, Cell adhesion molecule (CAM) interaction, Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, Lipid and atherosclerosis, Malaria, NF-kappa B signaling pathway, Primary immunodeficiency, Systemic lupus erythematosus, T cell receptor signaling pathway, Toxoplasmosis, Viral myocarditis 💬3件: 13, 222, 223 💬
63 Furosemide 1件: FUROSEMIDE1件: Furosemide 💬 1件: SLC12A2 💬 3件: Pancreatic secretion, Salivary secretion, Vibrio cholerae infection 💬5件: 6, 57, 77, 86, 222 💬
64 Galactose 2件: D-Galactose; Galactose1件: Galactose 💬 --4件: 66, 171, 222, 257 💬
65 Gold 1件: Gold---71件: 2, 5, 6, 11, 13, 17, 19, 21, 22, 28, 34, 35, 46, 49, 50, 53, 54, 56, 57, 58, 60, 63, 64, 65, 66, 68, 71, 75, 76, 77, 79, 84, 85, 86, 88, 91, 93, 95, 96, 97, 98, 107, 113, 127, 137, 158, 162, 167, 171, 193, 206, 215, 218, 222, 223, 224, 226, 227, 228, 230, 235, 271, 291, 294, 296, 298, 299, 310, 318, 331, 340 💬
66 Hydrochlorothiazide 1件: Hydrochlorothiazide1件: Hydrochlorothiazide 💬 1件: SLC12A3 💬 1件: Parathyroid hormone synthesis, secretion and action 💬5件: 13, 67, 222, 225, 235 💬
67 Hydroxychloroquine 2件: HYDROXYCHLOROQUINE; HYDROXYCHLOROQUINE SULFATE2件: Hydroxychloroquine sulfate ,
Hydroxychloroquine 💬 		--29件: 6, 13, 34, 41, 43, 44, 45, 46, 48, 49, 53, 56, 63, 66, 84, 89, 90, 96, 97, 107, 218, 222, 223, 224, 234, 254, 271, 298, 299 💬
68 Indobufen 1件: Indobufen1件: Indobufen 💬 2件: PTGS1,
PTGS2 💬 		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Efferocytosis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬1件: 222 💬
69 Iptacopan 1件: Iptacopan2件: Iptacopan ,
Iptacopan hydrochloride 💬 		1件: CFB 💬 3件: Complement and coagulation cascades, Coronavirus disease, Staphylococcus aureus infection 💬8件: 11, 61, 62, 63, 66, 109, 222, 223 💬
70 Irbesartan 1件: Irbesartan1件: Irbesartan 💬 1件: AGTR1 💬 17件: AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Hormone signaling, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬6件: 57, 66, 167, 168, 222, 223 💬
71 Lanraplenib 1件: Lanraplenib1件: Lanraplenib 💬 --2件: 53, 222 💬
72 Lansoprazole 1件: LANSOPRAZOLE1件: Lansoprazole 💬 2件: ATP4A,
ATP4B 💬 		3件: Collecting duct acid secretion, Gastric acid secretion, Oxidative phosphorylation 💬8件: 63, 71, 85, 98, 166, 222, 223, 299 💬
73 Levamisole 2件: Levamisole; LEVAMISOLE HYDROCHLORIDE2件: Levamisole hydrochloride ,
Levamisole 💬 		--4件: 60, 61, 62, 222 💬
74 Lisinopril 1件: Lisinopril2件: Lisinopril ,
Lisinopril 💬 		1件: ACE 💬 6件: Chagas disease, Coronavirus disease, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬9件: 19, 46, 49, 57, 66, 67, 113, 222, 223 💬
75 Losartan 2件: Losartan; LOSARTAN POTASSIUM2件: Losartan potassium ,
Losartan 💬 		1件: AGTR1 💬 17件: AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Hormone signaling, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬20件: 17, 19, 36, 46, 57, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 223, 299 💬
76 Losmapimod 1件: Losmapimod1件: Losmapimod 💬 4件: MAPK11,
MAPK12,
MAPK13,
MAPK14 💬 		64件: AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Alcoholic liver disease, Amyotrophic lateral sclerosis, C-type lectin receptor signaling pathway, Cadherin signaling, Cellular senescence, Chagas disease, Chemical carcinogenesis - reactive oxygen species, Coronavirus disease, Diabetic cardiomyopathy, Dopaminergic synapse, Efferocytosis, Epithelial cell signaling in Helicobacter pylori infection, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, FoxO signaling pathway, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hepatitis B, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, IL-17 signaling pathway, IgSF CAM signaling, Inflammatory mediator regulation of TRP channels, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Leukocyte transendothelial migration, Lipid and atherosclerosis, MAPK signaling pathway, NOD-like receptor signaling pathway, Neurotrophin signaling pathway, Neutrophil extracellular trap formation, Non-alcoholic fatty liver disease, Oocyte meiosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Platelet activation, Prion disease, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rap1 signaling pathway, Relaxin signaling pathway, Retrograde endocannabinoid signaling, Salmonella infection, Shigellosis, Signaling pathways regulating pluripotency of stem cells, Sphingolipid signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Thermogenesis, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, VEGF signaling pathway, Yersinia infection 💬2件: 113, 222 💬
77 Melphalan 2件: Melphalan; Melphalan Hydrochloride2件: Melphalan ,
Melphalan hydrochloride 💬 		--19件: 11, 13, 14, 19, 20, 28, 34, 46, 60, 62, 65, 96, 107, 164, 222, 234, 284, 285, 299 💬
78 Metformin 4件: Metformin; Metformin Hydrochloride; Metformina; Metformine2件: Metformin hydrochloride ,
Metformin 💬 		2件: PRKAA1,
PRKAA2 💬 		20件: AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬31件: 2, 6, 8, 13, 46, 49, 60, 65, 66, 67, 74, 75, 77, 81, 84, 85, 86, 97, 113, 127, 158, 206, 218, 222, 225, 233, 265, 285, 298, 299, 301 💬
79 Methylprednisolone 3件: Methylprednisolon; Methylprednisolone; Methylprednisolone acetate2件: Methylprednisolone ,
Methylprednisolone acetate 💬 		1件: NR3C1 💬 1件: Neuroactive ligand-receptor interaction 💬51件: 2, 6, 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 95, 96, 97, 111, 127, 145, 162, 164, 211, 222, 223, 224, 271, 283, 284, 285, 296, 300 💬
80 Methylprednisolone hemisuccinate 3件: METHYLPREDNISOLONE HEMISUCCINATE; Methylprednisolone sodium succinate; Methylprednisolone succinate2件: Methylprednisolone sodium succinate ,
Methylprednisolone hemisuccinate 💬 		1件: NR3C1 💬 1件: Neuroactive ligand-receptor interaction 💬8件: 13, 46, 49, 50, 51, 85, 211, 222 💬
81 Methylprednisone 1件: Methylprednisone---4件: 46, 66, 85, 222 💬
82 Metolazone 1件: Metolazone1件: Metolazone 💬 1件: SLC12A3 💬 1件: Parathyroid hormone synthesis, secretion and action 💬1件: 222 💬
83 Mizoribine 1件: Mizoribine1件: Mizoribine 💬 2件: IMPDH1,
IMPDH2 💬 		2件: Drug metabolism - other enzymes, Purine metabolism 💬8件: 46, 49, 51, 53, 66, 94, 222, 224 💬
84 Montelukast 2件: Montelukast; MONTELUKAST SODIUM2件: Montelukast sodium ,
Montelukast 💬 		1件: CYSLTR1 💬 2件: Calcium signaling pathway, Neuroactive ligand-receptor interaction 💬10件: 6, 13, 19, 46, 61, 63, 85, 98, 222, 228 💬
85 Mycophenolate mofetil 1件: Mycophenolate mofetil2件: Mycophenolate mofetil ,
Mycophenolate mofetil hydrochloride 💬 		2件: IMPDH1,
IMPDH2 💬 		2件: Drug metabolism - other enzymes, Purine metabolism 💬38件: 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 46, 49, 51, 53, 57, 60, 61, 62, 63, 65, 66, 93, 95, 96, 118, 162, 164, 222, 223, 224, 226, 234, 283, 284, 285, 300 💬
86 Mycophenolic acid 5件: Acido Micofenolico; MICOFENOLICO ACIDO; Mycophenolate; Mycophenolate sodium; Mycophenolic acid2件: Mycophenolate sodium ,
Mycophenolic acid 💬 		2件: IMPDH1,
IMPDH2 💬 		2件: Drug metabolism - other enzymes, Purine metabolism 💬11件: 11, 43, 49, 51, 53, 60, 66, 96, 222, 223, 228 💬
87 Narsoplimab 1件: Narsoplimab1件: Narsoplimab 💬 1件: MASP2 💬 3件: Complement and coagulation cascades, Coronavirus disease, Staphylococcus aureus infection 💬3件: 66, 222, 223 💬
88 Obinutuzumab 1件: Obinutuzumab1件: Obinutuzumab 💬 1件: MS4A1 💬 1件: Hematopoietic cell lineage 💬6件: 43, 44, 49, 63, 222, 223 💬
89 Ofatumumab 2件: HuMax-CD20; OFATUMUMAB1件: Ofatumumab 💬 1件: MS4A1 💬 1件: Hematopoietic cell lineage 💬6件: 11, 13, 35, 46, 222, 223 💬
90 Peginterferon alfa-2a 1件: Peginterferon alfa-2a1件: Peginterferon alfa-2a 💬 2件: IFNAR1,
IFNAR2 💬 		18件: Coronavirus disease, Cytokine-cytokine receptor interaction, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Measles, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Osteoclast differentiation, PI3K-Akt signaling pathway, Pathways in cancer, Toll-like receptor signaling pathway 💬1件: 222 💬
91 Pentoxifylline 1件: Pentoxifylline1件: Pentoxifylline 💬 --13件: 6, 26, 46, 56, 84, 93, 96, 97, 113, 222, 223, 296, 298 💬
92 Perindopril 2件: PERINDOPRIL; Perindopril arginine3件: Perindopril erbumine ,
Perindopril ,
Perindopril arginine 💬 		1件: ACE 💬 6件: Chagas disease, Coronavirus disease, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬5件: 57, 58, 113, 167, 222 💬
93 Pirfenidone 1件: Pirfenidone1件: Pirfenidone 💬 6件: CCL2,
IL10,
IL1A,
IL1B,
IL6,
TNF 💬 		83件: AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antigen processing and presentation, Apoptosis, Asthma, Autoimmune thyroid disease, C-type lectin receptor signaling pathway, Cellular senescence, Chagas disease, Chemokine signaling pathway, Coronavirus disease, Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, Dilated cardiomyopathy, Efferocytosis, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Graft-versus-host disease, HIF-1 signaling pathway, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Inflammatory mediator regulation of TRP channels, Influenza A, Insulin resistance, Intestinal immune network for IgA production, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, Measles, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Staphylococcus aureus infection, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Transcriptional misregulation in cancer, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬12件: 13, 34, 40, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
94 Povetacicept 1件: Povetacicept1件: Povetacicept 💬 1件: TNFRSF13B 💬 3件: Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, Primary immunodeficiency 💬5件: 11, 61, 63, 66, 222 💬
95 Praliciguat 1件: Praliciguat1件: Praliciguat 💬 3件: GUCY1A1,
GUCY1A2,
GUCY1B1 💬 		10件: Circadian entrainment, Gap junction, Long-term depression, Oxytocin signaling pathway, Platelet activation, Purine metabolism, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬1件: 222 💬
96 Pravastatin 2件: Pravastatin; Pravastatin sodium2件: Pravastatin sodium ,
Pravastatin 💬 		1件: HMGCR 💬 3件: AMPK signaling pathway, Bile secretion, Terpenoid backbone biosynthesis 💬11件: 13, 46, 49, 67, 79, 96, 164, 210, 222, 265, 333 💬
97 Prednisolone 3件: Prednisolona; Prednisolone; Prednisolonum1件: Prednisolone 💬 1件: NR3C1 💬 1件: Neuroactive ligand-receptor interaction 💬48件: 3, 11, 13, 14, 18, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 54, 56, 57, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 111, 113, 145, 162, 222, 223, 251, 269, 271, 296, 299, 300 💬
98 Prednisolone acetate 1件: PREDNISOLONE ACETATE1件: Prednisolone acetate 💬 1件: NR3C1 💬 1件: Neuroactive ligand-receptor interaction 💬2件: 222, 223 💬
99 Prednisone 2件: PREDNISONA; PREDNISONE1件: Prednisone 💬 1件: NR3C1 💬 1件: Neuroactive ligand-receptor interaction 💬58件: 2, 11, 13, 14, 18, 19, 26, 28, 35, 40, 41, 42, 43, 44, 45, 46, 48, 49, 50, 51, 53, 60, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 90, 93, 95, 96, 97, 113, 127, 145, 162, 164, 205, 222, 223, 224, 228, 251, 269, 283, 284, 285, 288, 299, 300, 303, 307, 331 💬
100 Prednisone acetate 1件: Prednisone acetate1件: Prednisone acetate 💬 1件: NR3C1 💬 1件: Neuroactive ligand-receptor interaction 💬9件: 35, 40, 46, 49, 63, 66, 162, 222, 224 💬
101 R3R01 1件: R3R01---2件: 218, 222 💬
102 Ramipril 1件: Ramipril1件: Ramipril 💬 1件: ACE 💬 6件: Chagas disease, Coronavirus disease, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬10件: 46, 49, 57, 66, 67, 113, 218, 222, 223, 257 💬
103 Rilzabrutinib 1件: Rilzabrutinib1件: Rilzabrutinib 💬 1件: BTK 💬 7件: B cell receptor signaling pathway, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, NF-kappa B signaling pathway, Osteoclast differentiation, Platelet activation, Primary immunodeficiency 💬6件: 35, 61, 63, 222, 223, 300 💬
104 Ripertamab 1件: Ripertamab---4件: 11, 14, 63, 222 💬
105 Rituximab 1件: Rituximab1件: Rituximab 💬 1件: MS4A1 💬 1件: Hematopoietic cell lineage 💬54件: 11, 13, 14, 19, 26, 34, 35, 36, 40, 41, 42, 43, 44, 45, 46, 48, 49, 50, 51, 52, 53, 55, 56, 60, 61, 62, 63, 64, 65, 66, 83, 84, 85, 86, 88, 93, 94, 96, 97, 162, 172, 222, 223, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331 💬
106 Rivaroxaban 1件: Rivaroxaban1件: Rivaroxaban 💬 1件: F10 💬 1件: Complement and coagulation cascades 💬10件: 46, 48, 49, 56, 58, 75, 91, 210, 222, 271 💬
107 Rosiglitazone 2件: Rosiglitazone; Rosiglitazone maleate2件: Rosiglitazone maleate ,
Rosiglitazone 💬 		1件: PPARG 💬 12件: AMPK signaling pathway, Efferocytosis, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬7件: 46, 57, 75, 77, 97, 222, 265 💬
108 Sacubitril 1件: Sacubitril1件: Sacubitril 💬 1件: MME 💬 4件: Alzheimer disease, Hematopoietic cell lineage, Protein digestion and absorption, Renin-angiotensin system 💬4件: 28, 58, 210, 222 💬
109 Saquinavir 1件: Saquinavir2件: Saquinavir ,
Saquinavir mesylate 💬 		--4件: 86, 222, 223, 265 💬
110 Serine 2件: L-Serine; Serine1件: Serine 💬 --5件: 2, 6, 86, 96, 222 💬
111 Sinomenine 1件: Sinomenine---2件: 46, 222 💬
112 Sirolimus 2件: Rapamycin; Sirolimus1件: Sirolimus 💬 1件: MTOR 💬 52件: AMPK signaling pathway, Acute myeloid leukemia, Adipocytokine signaling pathway, Alzheimer disease, Amyotrophic lateral sclerosis, Apelin signaling pathway, Autophagy - animal, Autophagy - other, Breast cancer, Cellular senescence, Central carbon metabolism in cancer, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Diabetic cardiomyopathy, ErbB signaling pathway, Gastric cancer, Glioma, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatocellular carcinoma, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Huntington disease, Insulin resistance, Insulin signaling pathway, Integrated stress response (ISR) signaling pathway, Integrin signaling, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Longevity regulating pathway, Longevity regulating pathway - multiple species, Lysosome biogenesis, MicroRNAs in cancer, Neutrophil extracellular trap formation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Shigellosis, Spinocerebellar ataxia, Th17 cell differentiation, Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus, mTOR signaling pathway 💬46件: 6, 13, 15, 17, 19, 21, 34, 35, 36, 46, 48, 49, 51, 54, 57, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 97, 98, 111, 127, 137, 157, 158, 192, 222, 223, 227, 277, 278, 279, 280, 281, 283, 285, 300, 331 💬
113 Sparsentan 1件: Sparsentan1件: Sparsentan 💬 2件: AGTR1,
EDNRA 💬 		18件: AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Hormone signaling, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬4件: 66, 218, 222, 223 💬
114 Spironolactone 1件: Spironolactone1件: Spironolactone 💬 1件: NR3C2 💬 1件: Aldosterone-regulated sodium reabsorption 💬12件: 46, 57, 58, 67, 86, 113, 210, 214, 218, 222, 223, 225 💬
115 Succinic acid 1件: Sodium succinate---11件: 13, 46, 49, 50, 51, 81, 83, 95, 97, 211, 222 💬
116 Tacrolimus 1件: Tacrolimus2件: Tacrolimus ,
Tacrolimus 💬 		5件: PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬 		33件: Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬37件: 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 57, 60, 61, 62, 63, 65, 66, 95, 96, 97, 113, 151, 158, 164, 222, 223, 224, 226, 227, 228, 234, 283, 284, 285, 286, 299 💬
117 Telitacicept 1件: Telitacicept---14件: 11, 13, 14, 46, 48, 49, 51, 53, 63, 66, 162, 222, 223, 300 💬
118 Telmisartan 1件: Telmisartan1件: Telmisartan 💬 1件: AGTR1 💬 17件: AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Hormone signaling, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬5件: 6, 57, 66, 67, 222 💬
119 Tetracosactide 3件: Cosyntropin; Tetracosactide; Tetracosactide acetate2件: Cosyntropin ,
Tetracosactide acetate 💬 		1件: MC2R 💬 6件: Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome, Hormone signaling, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬4件: 83, 113, 145, 222 💬
120 Tolvaptan 1件: TOLVAPTAN1件: Tolvaptan 💬 1件: AVPR2 💬 4件: Hormone signaling, Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vasopressin-regulated water reabsorption 💬5件: 67, 72, 86, 222, 225 💬
121 Torasemide 1件: Torasemide1件: Torsemide 💬 1件: SLC12A2 💬 3件: Pancreatic secretion, Salivary secretion, Vibrio cholerae infection 💬1件: 222 💬
122 TRU-015 1件: TRU-015---3件: 46, 49, 222 💬
123 Valproic acid 3件: Divalproex sodium; VALPROATE SODIUM; Valproic acid3件: Divalproex sodium ,
Valproic acid ,
Valproate sodium 💬 		7件: ABAT,
ALDH5A1,
CACNA1G,
CACNA1H,
CACNA1I,
GAD1,
GAD2 💬 		16件: Alanine, aspartate and glutamate metabolism, Aldosterone synthesis and secretion, Butanoate metabolism, Calcium signaling pathway, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, GABAergic synapse, GnRH secretion, MAPK signaling pathway, Propanoate metabolism, Taurine and hypotaurine metabolism, Type I diabetes mellitus, Type II diabetes mellitus, Valine, leucine and isoleucine degradation, beta-Alanine metabolism 💬11件: 3, 5, 26, 34, 51, 65, 89, 90, 145, 222, 331 💬
124 Valsartan 1件: Valsartan1件: Valsartan 💬 1件: AGTR1 💬 17件: AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Hormone signaling, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬11件: 28, 57, 58, 66, 75, 86, 210, 218, 222, 223, 224 💬
125 Vitamin D 1件: Vitamin D---26件: 3, 6, 13, 15, 19, 41, 43, 44, 46, 49, 50, 68, 74, 93, 95, 96, 97, 98, 179, 222, 228, 235, 256, 274, 298, 299 💬
126 Voclosporin 1件: Voclosporin1件: Voclosporin 💬 5件: PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬 		33件: Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬2件: 49, 222 💬
127 Warfarin 3件: Warfarin; Warfarin Potassium; Warfarin Sodium3件: Warfarin sodium ,
Warfarin potassium ,
Warfarin 💬 		2件: NQO1,
VKORC1 💬 		5件: Chemical carcinogenesis - reactive oxygen species, Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Pathways in cancer, Ubiquinone and other terpenoid-quinone biosynthesis 💬15件: 6, 8, 13, 19, 46, 48, 49, 66, 85, 86, 88, 91, 96, 97, 222 💬
128 Zanubrutinib 1件: Zanubrutinib1件: Zanubrutinib 💬 1件: BTK 💬 7件: B cell receptor signaling pathway, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, NF-kappa B signaling pathway, Osteoclast differentiation, Platelet activation, Primary immunodeficiency 💬7件: 13, 48, 61, 63, 222, 300, 331 💬
129 Zinc 1件: Zinc---7件: 2, 56, 85, 171, 222, 223, 299 💬
130 ZUBERITAMAB 1件: ZUBERITAMAB---2件: 63, 222 💬