Target Gene/Pathway Pathway / Gene

  

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No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank 指定難病告示番号
1 AR 💬 4件: Oocyte meiosis, Pathways in cancer, Chemical carcinogenesis - receptor activation, Prostate cancer Testosterone 💬 Testosterone 9件: 1, 2, 3, 13, 60, 76, 78, 113, 265 💬
2 CYP19A1 💬 2件: Steroid hormone biosynthesis, Ovarian steroidogenesis Anastrozole 💬 Anastrozole 3件: 78, 86, 193 💬
3 ESR1 💬 9件: Hormone signaling, Estrogen signaling pathway, Prolactin signaling pathway, Thyroid hormone signaling pathway, Endocrine and other factor-regulated calcium reabsorption, Pathways in cancer, Proteoglycans in cancer, Chemical carcinogenesis - receptor activation, Breast cancer Estradiol hemihydrate 💬 Estradiol 9件: 13, 46, 49, 65, 76, 78, 118, 226, 299 💬
4 ESR1 💬 9件: Hormone signaling, Estrogen signaling pathway, Prolactin signaling pathway, Thyroid hormone signaling pathway, Endocrine and other factor-regulated calcium reabsorption, Pathways in cancer, Proteoglycans in cancer, Chemical carcinogenesis - receptor activation, Breast cancer Estradiol 💬 Estradiol 9件: 13, 46, 49, 65, 76, 78, 118, 226, 299 💬
5 ESR2 💬 7件: Hormone signaling, Estrogen signaling pathway, Prolactin signaling pathway, GnRH secretion, Pathways in cancer, Chemical carcinogenesis - receptor activation, Breast cancer Estradiol 💬 Estradiol 9件: 13, 46, 49, 65, 76, 78, 118, 226, 299 💬
6 ESR2 💬 7件: Hormone signaling, Estrogen signaling pathway, Prolactin signaling pathway, GnRH secretion, Pathways in cancer, Chemical carcinogenesis - receptor activation, Breast cancer Estradiol hemihydrate 💬 Estradiol 9件: 13, 46, 49, 65, 76, 78, 118, 226, 299 💬
7 GLP1R 💬 4件: cAMP signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Insulin secretion Exenatide 💬 Exenatide 6件: 6, 17, 72, 78, 193, 233 💬
8 MC2R 💬 6件: cAMP signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome Corticotropin, repository 💬 Corticotropin 10件: 2, 13, 46, 75, 78, 81, 84, 145, 205, 222 💬
9 MC2R 💬 6件: cAMP signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome Corticotropin 💬 Corticotropin 10件: 2, 13, 46, 75, 78, 81, 84, 145, 205, 222 💬
10 MTNR1A 💬 2件: Neuroactive ligand-receptor interaction, Circadian entrainment Melatonin 💬 Melatonin 18件: 2, 6, 8, 13, 37, 46, 49, 72, 78, 86, 90, 96, 97, 145, 149, 159, 202, 265 💬
11 MTNR1B 💬 2件: Neuroactive ligand-receptor interaction, Circadian entrainment Melatonin 💬 Melatonin 18件: 2, 6, 8, 13, 37, 46, 49, 72, 78, 86, 90, 96, 97, 145, 149, 159, 202, 265 💬
12 NR3C1 💬 1件: Neuroactive ligand-receptor interaction Hydrocortisone 💬 Hydrocortisone 10件: 6, 41, 46, 53, 75, 78, 81, 83, 97, 299 💬
13 PTGS1 💬 4件: Arachidonic acid metabolism, Platelet activation, Serotonergic synapse, Regulation of lipolysis in adipocytes Diclofenac potassium 💬 Diclofenac 5件: 13, 34, 46, 78, 271 💬
14 PTGS1 💬 4件: Arachidonic acid metabolism, Platelet activation, Serotonergic synapse, Regulation of lipolysis in adipocytes Diclofenac diethylamine 💬 Diclofenac 5件: 13, 34, 46, 78, 271 💬
15 PTGS1 💬 4件: Arachidonic acid metabolism, Platelet activation, Serotonergic synapse, Regulation of lipolysis in adipocytes Diclofenac epolamine 💬 Diclofenac 5件: 13, 34, 46, 78, 271 💬
16 PTGS1 💬 4件: Arachidonic acid metabolism, Platelet activation, Serotonergic synapse, Regulation of lipolysis in adipocytes Diclofenac 💬 Diclofenac 5件: 13, 34, 46, 78, 271 💬
17 PTGS1 💬 4件: Arachidonic acid metabolism, Platelet activation, Serotonergic synapse, Regulation of lipolysis in adipocytes Diclofenac sodium 💬 Diclofenac 5件: 13, 34, 46, 78, 271 💬
18 PTGS2 💬 22件: Arachidonic acid metabolism, NF-kappa B signaling pathway, Efferocytosis, VEGF signaling pathway, C-type lectin receptor signaling pathway, IL-17 signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Ovarian steroidogenesis, Oxytocin signaling pathway, Regulation of lipolysis in adipocytes, Alzheimer disease, Pathways of neurodegeneration - multiple diseases, Leishmaniasis, Human cytomegalovirus infection, Human papillomavirus infection, Kaposi sarcoma-associated herpesvirus infection, Pathways in cancer, Chemical carcinogenesis - DNA adducts, MicroRNAs in cancer, Small cell lung cancer Diclofenac 💬 Diclofenac 5件: 13, 34, 46, 78, 271 💬
19 PTGS2 💬 22件: Arachidonic acid metabolism, NF-kappa B signaling pathway, Efferocytosis, VEGF signaling pathway, C-type lectin receptor signaling pathway, IL-17 signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Ovarian steroidogenesis, Oxytocin signaling pathway, Regulation of lipolysis in adipocytes, Alzheimer disease, Pathways of neurodegeneration - multiple diseases, Leishmaniasis, Human cytomegalovirus infection, Human papillomavirus infection, Kaposi sarcoma-associated herpesvirus infection, Pathways in cancer, Chemical carcinogenesis - DNA adducts, MicroRNAs in cancer, Small cell lung cancer Diclofenac potassium 💬 Diclofenac 5件: 13, 34, 46, 78, 271 💬
20 PTGS2 💬 22件: Arachidonic acid metabolism, NF-kappa B signaling pathway, Efferocytosis, VEGF signaling pathway, C-type lectin receptor signaling pathway, IL-17 signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Ovarian steroidogenesis, Oxytocin signaling pathway, Regulation of lipolysis in adipocytes, Alzheimer disease, Pathways of neurodegeneration - multiple diseases, Leishmaniasis, Human cytomegalovirus infection, Human papillomavirus infection, Kaposi sarcoma-associated herpesvirus infection, Pathways in cancer, Chemical carcinogenesis - DNA adducts, MicroRNAs in cancer, Small cell lung cancer Diclofenac sodium 💬 Diclofenac 5件: 13, 34, 46, 78, 271 💬
21 PTGS2 💬 22件: Arachidonic acid metabolism, NF-kappa B signaling pathway, Efferocytosis, VEGF signaling pathway, C-type lectin receptor signaling pathway, IL-17 signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Ovarian steroidogenesis, Oxytocin signaling pathway, Regulation of lipolysis in adipocytes, Alzheimer disease, Pathways of neurodegeneration - multiple diseases, Leishmaniasis, Human cytomegalovirus infection, Human papillomavirus infection, Kaposi sarcoma-associated herpesvirus infection, Pathways in cancer, Chemical carcinogenesis - DNA adducts, MicroRNAs in cancer, Small cell lung cancer Diclofenac epolamine 💬 Diclofenac 5件: 13, 34, 46, 78, 271 💬
22 PTGS2 💬 22件: Arachidonic acid metabolism, NF-kappa B signaling pathway, Efferocytosis, VEGF signaling pathway, C-type lectin receptor signaling pathway, IL-17 signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Ovarian steroidogenesis, Oxytocin signaling pathway, Regulation of lipolysis in adipocytes, Alzheimer disease, Pathways of neurodegeneration - multiple diseases, Leishmaniasis, Human cytomegalovirus infection, Human papillomavirus infection, Kaposi sarcoma-associated herpesvirus infection, Pathways in cancer, Chemical carcinogenesis - DNA adducts, MicroRNAs in cancer, Small cell lung cancer Diclofenac diethylamine 💬 Diclofenac 5件: 13, 34, 46, 78, 271 💬
23 THRA 💬 3件: Neuroactive ligand-receptor interaction, Hormone signaling, Thyroid hormone signaling pathway Levothyroxine 💬 Levothyroxine 3件: 49, 78, 80 💬
24 THRA 💬 3件: Neuroactive ligand-receptor interaction, Hormone signaling, Thyroid hormone signaling pathway Levothyroxine sodium 💬 Levothyroxine 3件: 49, 78, 80 💬
25 THRA 💬 3件: Neuroactive ligand-receptor interaction, Hormone signaling, Thyroid hormone signaling pathway Levothyroxine sodium 💬 Levothyroxine 3件: 49, 78, 80 💬
26 THRB 💬 3件: Neuroactive ligand-receptor interaction, Hormone signaling, Thyroid hormone signaling pathway Levothyroxine sodium 💬 Levothyroxine 3件: 49, 78, 80 💬
27 THRB 💬 3件: Neuroactive ligand-receptor interaction, Hormone signaling, Thyroid hormone signaling pathway Levothyroxine 💬 Levothyroxine 3件: 49, 78, 80 💬
28 THRB 💬 3件: Neuroactive ligand-receptor interaction, Hormone signaling, Thyroid hormone signaling pathway Levothyroxine sodium 💬 Levothyroxine 3件: 49, 78, 80 💬