Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank Drug (Description in trials) KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1 Abacavir [2] Abacavir; Abacavir sulfate[2] Abacavir sulfate ,
Abacavir 💬 		--[4] 2, 135, 265, 325 💬
2 Abatacept [1] Abatacept[1] Abatacept 💬 [2] CD80,
CD86 💬 		[13] Allograft rejection, Autoimmune thyroid disease, Cell adhesion molecules, Graft-versus-host disease, Intestinal immune network for IgA production, Kaposi sarcoma-associated herpesvirus infection, Rheumatoid arthritis, Systemic lupus erythematosus, Toll-like receptor signaling pathway, Transcriptional misregulation in cancer, Type I diabetes mellitus, Viral myocarditis, Virion - Adenovirus 💬[27] 2, 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
3 ABBV-CLS-7262 [1] ABBV-CLS-7262---[1] 2 💬
4 Abemaciclib [1] Abemaciclib[1] Abemaciclib 💬 [2] CDK4,
CDK6 💬 		[28] AGE-RAGE signaling pathway in diabetic complications, Bladder cancer, Breast cancer, Cell cycle, Cellular senescence, Chronic myeloid leukemia, Cushing syndrome, Epstein-Barr virus infection, Glioma, Hepatitis C, Hepatocellular carcinoma, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, Kaposi sarcoma-associated herpesvirus infection, Measles, Melanoma, MicroRNAs in cancer, Non-small cell lung cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Small cell lung cancer, T cell receptor signaling pathway, Tight junction, Viral carcinogenesis, p53 signaling pathway 💬[1] 34 💬
5 Abetimus [1] Abetimus sodium[1] Abetimus sodium 💬 --[1] 49 💬
6 ABH001 [1] ABH001---[1] 36 💬
7 Abiraterone [1] Abiraterone acetate[1] Abiraterone acetate 💬 [1] CYP17A 💬 [5] Cortisol synthesis and secretion, Cushing syndrome, Ovarian steroidogenesis, Prolactin signaling pathway, Steroid hormone biosynthesis 💬[2] 75, 81 💬
8 Abituzumab [1] Abituzumab---[1] 51 💬
9 Abrilumab [1] Abrilumab[1] Abrilumab 💬 [2] ITGA4,
ITGB7 💬 		[16] Arrhythmogenic right ventricular cardiomyopathy, Cell adhesion molecules, Cytoskeleton in muscle cells, Dilated cardiomyopathy, ECM-receptor interaction, Focal adhesion, Hematopoietic cell lineage, Human papillomavirus infection, Hypertrophic cardiomyopathy, Intestinal immune network for IgA production, Leishmaniasis, Leukocyte transendothelial migration, PI3K-Akt signaling pathway, Regulation of actin cytoskeleton, Transcriptional misregulation in cancer, Yersinia infection 💬[2] 96, 97 💬
10 Abrocitinib [1] Abrocitinib[1] Abrocitinib 💬 [1] JAK1 💬 [27] Coronavirus disease - COVID-19, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Measles, NOD-like receptor signaling pathway, Necroptosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬[2] 39, 84 💬
11 ABX-1431 [0] ---[1] 13 💬
12 ABX1100 [0] ---[1] 256 💬
13 Acacia [1] GUM arabic[1] Acacia 💬 --[2] 46, 97 💬
14 Acalabrutinib [1] Acalabrutinib[2] Acalabrutinib ,
Acalabrutinib maleate hydrate 💬 		[1] BTK 💬 [7] B cell receptor signaling pathway, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, NF-kappa B signaling pathway, Osteoclast differentiation, Platelet activation, Primary immunodeficiency 💬[2] 46, 61 💬
15 Acamprosate [1] Acamprosate[2] Acamprosate calcium ,
Acamprosate 💬 		[5] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬 		[21] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[2] 6, 206 💬
16 Acarbose [1] Acarbose[1] Acarbose 💬 [5] AMY,
AMY,
GAA,
GANC,
MGAM 💬 		[6] Carbohydrate digestion and absorption, Galactose metabolism, Lysosome, Pancreatic secretion, Salivary secretion, Starch and sucrose metabolism 💬[1] 298 💬
17 Acazicolcept [1] Acazicolcept[1] Acazicolcept 💬 [2] CD28,
ICOS 💬 		[13] Allograft rejection, Autoimmune thyroid disease, Cell adhesion molecules, Graft-versus-host disease, Intestinal immune network for IgA production, Measles, PD-L1 expression and PD-1 checkpoint pathway in cancer, Primary immunodeficiency, Rheumatoid arthritis, Systemic lupus erythematosus, T cell receptor signaling pathway, Type I diabetes mellitus, Viral myocarditis 💬[1] 49 💬
18 Acebilustat [1] Acebilustat---[1] 299 💬
19 Aceclofenac [1] Aceclofenac[1] Aceclofenac 💬 [3] PTGES,
PTGS1,
PTGS2 💬 		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Efferocytosis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[1] 46 💬
20 Aceneuramic acid [1] Aceneuramic acid[1] Aceneuramic acid 💬 --[1] 30 💬
21 Acetamide [1] Acetamide---[1] 65 💬
22 Acetaminophen [2] Acetaminophen; Paracetamol[1] Acetaminophen 💬 [2] PTGS1,
PTGS2 💬 		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Efferocytosis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[18] 3, 6, 11, 13, 19, 34, 35, 46, 49, 51, 70, 77, 86, 96, 222, 256, 300, 337 💬
23 Acetate [1] Acetate---[14] 11, 46, 49, 51, 70, 71, 73, 76, 89, 97, 158, 235, 265, 299 💬
24 Acetazolamide [1] Acetazolamide[2] Acetazolamide ,
Acetazolamide sodium 💬 		[13] CA,
CA,
CA,
CA,
CA,
CA,
CA,
CA,
CA,
CA,
CA,
CA2,
CA4 💬 		[6] Bile secretion, Collecting duct acid secretion, Gastric acid secretion, Nitrogen metabolism, Pancreatic secretion, Proximal tubule bicarbonate reclamation 💬[6] 13, 90, 115, 155, 225, 230 💬
25 Acetic acid [2] Acetic acid; Ethanoate[1] Acetic acid, glacial 💬 --[3] 97, 251, 296 💬
26 Acetic acid C-11 [1] 11C-acetate---[3] 13, 86, 88 💬
27 Acetohydroxamic acid [1] Acetohydroxamic acid[1] Acetohydroxamic acid 💬 --[1] 251 💬
28 Acetylcarnitine [2] Acetyl-L-carnitine; Acetylcarnitine---[4] 2, 97, 265, 298 💬
29 Acetylcysteine [1] Acetylcysteine[1] Acetylcysteine 💬 --[12] 8, 34, 51, 53, 85, 90, 94, 97, 193, 233, 298, 299 💬
30 Acetylsalicylic acid [2] Acetylsalicylic acid; Aspirin[1] Aspirin 💬 [2] PTGS1,
PTGS2 💬 		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Efferocytosis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[15] 13, 22, 34, 46, 49, 51, 64, 86, 96, 97, 113, 158, 210, 231, 271 💬
31 Acipimox [1] Acipimox[1] Acipimox 💬 --[2] 78, 265 💬
32 Acitretin [1] Acitretin[1] Acitretin 💬 [5] RARA,
RARB,
RXRA,
RXRB,
RXRG 💬 		[20] Acute myeloid leukemia, Adipocytokine signaling pathway, Bile secretion, Chemical carcinogenesis - receptor activation, Efferocytosis, Estrogen signaling pathway, Gastric cancer, Hepatitis C, Lipid and atherosclerosis, Non-alcoholic fatty liver disease, Non-small cell lung cancer, PI3K-Akt signaling pathway, PPAR signaling pathway, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Small cell lung cancer, Th17 cell differentiation, Thyroid cancer, Thyroid hormone signaling pathway, Transcriptional misregulation in cancer 💬[1] 37 💬
33 Acoramidis [1] Acoramidis[1] Acoramidis 💬 [1] TTR 💬 [1] Thyroid hormone synthesis 💬[1] 28 💬
34 Acotiamide [1] Acotiamide---[2] 11, 51 💬
35 ACP-015 [1] Transcon CNP---[1] 276 💬
36 ACR325 [1] ACR325---[1] 6 💬
37 Activated charcoal [2] Activated charcoal; Carbon[1] Charcoal, activated 💬 --[11] 6, 13, 51, 62, 85, 86, 97, 149, 158, 235, 298 💬
38 ACTUS-101 [1] Actus-101---[1] 256 💬
39 Acyclovir [3] Aciclovir; Acycloguanosine; Acyclovir[2] Acyclovir ,
Acyclovir sodium 💬 		--[5] 13, 28, 46, 53, 60 💬
40 Adalimumab [1] Adalimumab[1] Adalimumab 💬 [1] TNF 💬 [66] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[21] 19, 37, 38, 40, 41, 46, 55, 56, 84, 96, 97, 107, 151, 160, 162, 164, 222, 226, 269, 270, 271 💬
41 Adefovir [1] Adefovir[1] Adefovir 💬 --[1] 46 💬
42 Ademetionine [2] SAM-E; Same[1] Ademetionine 💬 --[2] 6, 94 💬
43 Adenosine [1] Adenosine[1] Adenosine 💬 [4] ADORA1,
ADORA2A,
ADORA2B,
ADORA3 💬 		[13] Alcoholism, Calcium signaling pathway, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[3] 13, 58, 65 💬
44 Adenosine phosphate [0] [1] Adenosine phosphate 💬 [4] ADORA1,
ADORA2A,
ADORA2B,
ADORA3 💬 		[13] Alcoholism, Calcium signaling pathway, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 46 💬
45 Adipose-Derived Mesenchymal Stem Cells: Autologous or Allogeneic Origins [2] Admsc; HB-admscs---[9] 2, 4, 6, 13, 14, 46, 49, 51, 96 💬
46 ADL5859 [1] ADL5859---[1] 46 💬
47 Adrabetadex [1] Adrabetadex---[1] 19 💬
48 Adrenomedullin [1] Adrenomedullin---[3] 96, 97, 124 💬
49 Afamelanotide [1] Afamelanotide[2] Afamelanotide ,
Afamelanotide acetate 💬 		[1] MC1R 💬 [3] Hormone signaling, Melanogenesis, Neuroactive ligand-receptor interaction 💬[2] 159, 254 💬
50 Afatinib [1] Afatinib[2] Afatinib ,
Afatinib dimaleate 💬 		[3] EGFR,
ERBB2,
ERBB4 💬 		[49] Adherens junction, Amyotrophic lateral sclerosis, Bladder cancer, Breast cancer, Calcium signaling pathway, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Coronavirus disease - COVID-19, Cushing syndrome, Endocytosis, Endometrial cancer, Epithelial cell signaling in Helicobacter pylori infection, ErbB signaling pathway, Estrogen signaling pathway, Focal adhesion, FoxO signaling pathway, Gap junction, Gastric cancer, Glioma, GnRH signaling pathway, HIF-1 signaling pathway, Hepatitis C, Hepatocellular carcinoma, Human cytomegalovirus infection, Human papillomavirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanoma, MicroRNAs in cancer, Non-small cell lung cancer, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis, Tight junction, Virion - Hepatitis viruses 💬[1] 285 💬
51 Afegostat [1] Afegostat tartrate[2] Afegostat ,
Afegostat tartrate 💬 		--[1] 19 💬
52 Aficamten [1] Aficamten[1] Aficamten 💬 [5] MYH6_7,
MYH6_7,
MYL2,
MYL3,
MYL4 💬 		[17] Adherens junction, Adrenergic signaling in cardiomyocytes, Apelin signaling pathway, Cardiac muscle contraction, Cytoskeleton in muscle cells, Dilated cardiomyopathy, Focal adhesion, Hypertrophic cardiomyopathy, Leukocyte transendothelial migration, Motor proteins, Regulation of actin cytoskeleton, Salmonella infection, Shigellosis, Thyroid hormone signaling pathway, Tight junction, Viral myocarditis, cGMP-PKG signaling pathway 💬[1] 58 💬
53 Afimetoran [1] Afimetoran[1] Afimetoran 💬 --[1] 49 💬
54 Aflibercept [1] Aflibercept[1] Aflibercept 💬 [3] PGF,
VEGFA,
VEGFB 💬 		[23] AGE-RAGE signaling pathway in diabetic complications, Bladder cancer, Calcium signaling pathway, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Fluid shear stress and atherosclerosis, Focal adhesion, HIF-1 signaling pathway, Human cytomegalovirus infection, Human papillomavirus infection, Kaposi sarcoma-associated herpesvirus infection, MAPK signaling pathway, MicroRNAs in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Relaxin signaling pathway, Renal cell carcinoma, Rheumatoid arthritis, VEGF signaling pathway 💬[2] 90, 166 💬
55 AGA2115 [1] AGA2115---[1] 274 💬
56 Agalsidase alfa [3] Agalsidase alfa; Agalsidase alpha; Recombinant alpha-galactosidase A[1] Agalsidase alfa 💬 [1] GLA 💬 [5] Galactose metabolism, Glycerolipid metabolism, Glycosphingolipid biosynthesis - globo and isoglobo series, Lysosome, Sphingolipid metabolism 💬[1] 19 💬
57 Agalsidase beta [1] Agalsidase beta[1] Agalsidase beta 💬 [1] GLA 💬 [5] Galactose metabolism, Glycerolipid metabolism, Glycosphingolipid biosynthesis - globo and isoglobo series, Lysosome, Sphingolipid metabolism 💬[1] 19 💬
58 Agomelatine [0] [1] Agomelatine 💬 [3] HTR2,
MTNR1A,
MTNR1B 💬 		[7] Calcium signaling pathway, Circadian entrainment, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Serotonergic synapse 💬[1] 6 💬
59 AGT-182 [1] AGT-182---[1] 19 💬
60 AK106-001616 [1] AK106-001616---[1] 46 💬
61 Alanine [1] Alanine[1] Alanine 💬 --[3] 70, 94, 298 💬
62 Albendazole [2] Albendazole; Eskazole[1] Albendazole 💬 --[1] 96 💬
63 Albumin human [3] Albumin; Human albumin; Serum albumin[2] Albumin human ,
Human serum albumin 💬 		--[7] 2, 11, 50, 96, 97, 222, 296 💬
64 Albuterol [2] Albuterol; Salbutamol[2] Albuterol sulfate ,
Albuterol 💬 		[1] ADRB2 💬 [11] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[16] 2, 3, 11, 12, 13, 85, 86, 89, 111, 113, 228, 231, 256, 273, 299, 340 💬
65 Aldafermin [1] Aldafermin[1] Aldafermin 💬 [1] FGF19 💬 [10] Breast cancer, Calcium signaling pathway, Gastric cancer, MAPK signaling pathway, Melanoma, PI3K-Akt signaling pathway, Pathways in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton 💬[1] 94 💬
66 Aldesleukin [3] Aldesleukin; ILT-101; Recombinant human interleukin-2[1] Aldesleukin 💬 [3] IL2RA,
IL2RB,
IL2RG 💬 		[14] Cytokine-cytokine receptor interaction, Endocytosis, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, Inflammatory bowel disease, JAK-STAT signaling pathway, Measles, PI3K-Akt signaling pathway, Pathways in cancer, Primary immunodeficiency, Th1 and Th2 cell differentiation, Th17 cell differentiation, Transcriptional misregulation in cancer, Viral protein interaction with cytokine and cytokine receptor 💬[6] 2, 35, 49, 65, 96, 97 💬
67 Aldosterone [1] Aldosterone[1] Aldosterone 💬 [1] NR3C2 💬 [1] Aldosterone-regulated sodium reabsorption 💬[1] 222 💬
68 Alefacept [1] Alefacept[1] Alefacept 💬 [1] CD58 💬 [2] Cell adhesion molecules, Epstein-Barr virus infection 💬[6] 37, 60, 65, 164, 284, 285 💬
69 Alemtuzumab [1] Alemtuzumab[1] Alemtuzumab 💬 --[20] 13, 15, 19, 20, 36, 43, 44, 46, 51, 60, 63, 65, 85, 96, 107, 164, 283, 284, 285, 326 💬
70 Alendronic acid [3] Alendronate; Alendronate sodium; Alendronic acid[2] Alendronate sodium ,
Alendronic acid 💬 		[1] FDPS 💬 [3] Human T-cell leukemia virus 1 infection, Influenza A, Terpenoid backbone biosynthesis 💬[7] 19, 41, 46, 50, 271, 274, 299 💬
71 Alfacalcidol [1] Alfacalcidol[1] Alfacalcidol 💬 [1] VDR 💬 [5] Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬[7] 41, 46, 50, 96, 107, 235, 238 💬
72 Alfuzosin [1] Alfuzosin[2] Alfuzosin hydrochloride ,
Alfuzosin 💬 		[1] ADRA1A 💬 [9] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 13 💬
73 Alginic acid [4] Algin; Alginate; Alginic acid; Sodium alginate[2] Alginic acid ,
Sodium alginate 💬 		--[4] 51, 53, 97, 299 💬
74 Alglucosidase alfa [2] Alglucosidase alfa; Alpha-glucosidase[1] Alglucosidase alfa 💬 [1] GAA 💬 [3] Galactose metabolism, Lysosome, Starch and sucrose metabolism 💬[1] 256 💬
75 Alicaforsen [1] Alicaforsen[1] Alicaforsen sodium 💬 [1] ICAM1 💬 [17] AGE-RAGE signaling pathway in diabetic complications, African trypanosomiasis, Cell adhesion molecules, Epstein-Barr virus infection, Fluid shear stress and atherosclerosis, Human T-cell leukemia virus 1 infection, Influenza A, Kaposi sarcoma-associated herpesvirus infection, Leukocyte transendothelial migration, Lipid and atherosclerosis, Malaria, NF-kappa B signaling pathway, Natural killer cell mediated cytotoxicity, Rheumatoid arthritis, Staphylococcus aureus infection, TNF signaling pathway, Viral myocarditis 💬[2] 96, 97 💬
76 Alirinetide [2] GM604; GM608---[2] 2, 6 💬
77 Alirocumab [1] Alirocumab[1] Alirocumab 💬 [1] PCSK9 💬 [1] Cholesterol metabolism 💬[1] 79 💬
78 Aliskiren [1] Aliskiren[2] Aliskiren ,
Aliskiren fumarate 💬 		[1] REN 💬 [3] Diabetic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬[3] 66, 167, 222 💬
79 Alitretinoin [1] Alitretinoin[1] Alitretinoin 💬 [5] RARA,
RARB,
RXRA,
RXRB,
RXRG 💬 		[20] Acute myeloid leukemia, Adipocytokine signaling pathway, Bile secretion, Chemical carcinogenesis - receptor activation, Efferocytosis, Estrogen signaling pathway, Gastric cancer, Hepatitis C, Lipid and atherosclerosis, Non-alcoholic fatty liver disease, Non-small cell lung cancer, PI3K-Akt signaling pathway, PPAR signaling pathway, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Small cell lung cancer, Th17 cell differentiation, Thyroid cancer, Thyroid hormone signaling pathway, Transcriptional misregulation in cancer 💬[1] 49 💬
80 Alkaline Phosphatase [1] Alkaline phosphatase---[3] 46, 93, 97 💬
81 Allantoin [1] Allantoin[1] Allantoin 💬 --[1] 36 💬
82 Allogeneic Cardiosphere-Derived Cells [1] Allogeneic cardiosphere-derived cells---[1] 113 💬
83 Allogeneic umbilical cord mesenchymal stem cells [1] Allogeneic umbilical cord mesenchymal stem cells---[1] 13 💬
84 Allogenic bone marrow-derived mesenchymal stem cells [4] Allogeneic bone marrow derived human mesenchymal stem cells; Allogeneic bone marrow-derived mesenchymal stromal cells; Longeveron mesenchymal stem cells; OSSM-001---[3] 96, 97, 211 💬
85 Allogenic Donor CD362-enriched Human Umbilical Cord-derived Mesenchymal Stem Cells [1] Orbcel-C---[2] 94, 95 💬
86 Allopurinol [2] Allopurinol; Allopurinol sodium[2] Allopurinol ,
Allopurinol sodium 💬 		[1] XDH 💬 [4] Caffeine metabolism, Drug metabolism - other enzymes, Peroxisome, Purine metabolism 💬[7] 6, 46, 57, 60, 66, 96, 97 💬
87 Aloe vera leaf [0] [1] Aloe 💬 --[1] 97 💬
88 Alogabat [1] Alogabat[1] Alogabat 💬 [1] GABRA 💬 [7] GABAergic synapse, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Taste transduction 💬[1] 201 💬
89 Alovudine [1] Alovudine[1] Alovudine 💬 --[1] 6 💬
90 Alpelisib [1] Alpelisib[1] Alpelisib 💬 [1] PIK3CA_B_D 💬 [103] AGE-RAGE signaling pathway in diabetic complications, AMPK signaling pathway, Acute myeloid leukemia, Aldosterone-regulated sodium reabsorption, Alzheimer disease, Amoebiasis, Apoptosis, Autophagy - animal, Axon guidance, B cell receptor signaling pathway, Bacterial invasion of epithelial cells, Breast cancer, C-type lectin receptor signaling pathway, Carbohydrate digestion and absorption, Cellular senescence, Central carbon metabolism in cancer, Chagas disease, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Choline metabolism in cancer, Cholinergic synapse, Chronic myeloid leukemia, Colorectal cancer, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Endometrial cancer, Epstein-Barr virus infection, ErbB signaling pathway, Estrogen signaling pathway, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagocytosis, Fluid shear stress and atherosclerosis, Focal adhesion, FoxO signaling pathway, Gastric cancer, Glioma, GnRH secretion, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatitis B, Hepatitis C, Hepatocellular carcinoma, Herpes simplex virus 1 infection, Hormone signaling, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Inflammatory mediator regulation of TRP channels, Influenza A, Inositol phosphate metabolism, Insulin resistance, Insulin signaling pathway, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leukocyte transendothelial migration, Lipid and atherosclerosis, Longevity regulating pathway, Longevity regulating pathway - multiple species, Measles, Melanoma, MicroRNAs in cancer, Natural killer cell mediated cytotoxicity, Neurotrophin signaling pathway, Neutrophil extracellular trap formation, Non-alcoholic fatty liver disease, Non-small cell lung cancer, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Phosphatidylinositol signaling system, Phospholipase D signaling pathway, Platelet activation, Prion disease, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Regulation of lipolysis in adipocytes, Relaxin signaling pathway, Renal cell carcinoma, Salmonella infection, Shigellosis, Signaling pathways regulating pluripotency of stem cells, Small cell lung cancer, Sphingolipid signaling pathway, Spinocerebellar ataxia, T cell receptor signaling pathway, TNF signaling pathway, Thyroid hormone signaling pathway, Toll-like receptor signaling pathway, Type II diabetes mellitus, VEGF signaling pathway, Viral carcinogenesis, Yersinia infection, cAMP signaling pathway, mTOR signaling pathway 💬[4] 138, 278, 279, 280 💬
91 Alpha-1-proteinase inhibitor [4] Alpha 1-antitrypsin; Alpha 1-proteinase inhibitor; Alpha-1-antitrypsin; Alpha1-proteinase inhibitor[1] alpha 1-Antitrypsin 💬 [1] SERPINA1 💬 [1] Complement and coagulation cascades 💬[3] 231, 298, 299 💬
92 alpha-Linolenic acid [0] ---[1] 286 💬
93 alpha-Tocopherol acetate [3] Tocopherol acetate; Tocopheryl acetate; Vitamin E[1] Tocopherol acetate 💬 --[2] 49, 206 💬
94 Alprazolam [1] Alprazolam[1] Alprazolam 💬 [16] GABRA,
GABRA,
GABRA,
GABRA,
GABRA,
GABRA,
GABRB,
GABRB,
GABRB,
GABRD,
GABRE,
GABRG,
GABRG,
GABRG,
GABRP,
GABRQ 💬 		[8] GABAergic synapse, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[2] 8, 75 💬
95 Alprostadil [1] Alprostadil[1] Alprostadil 💬 [1] PTGER1 💬 [4] Calcium signaling pathway, Human cytomegalovirus infection, Neuroactive ligand-receptor interaction, Pathways in cancer 💬[2] 51, 70 💬
96 Altropane [1] Altropane---[1] 6 💬
97 ALTU-135 [1] ALTU-135---[1] 299 💬
98 Alunacedase alfa [0] ---[1] 86 💬
99 Alvelestat [1] Alvelestat---[1] 231 💬
100 ALX-009 [1] ALX-009---[1] 299 💬
101 Amantadine [3] Amantadine; Amantadine hydrochloride; Amantadine sulfate[2] Amantadine hydrochloride ,
Amantadine 💬 		[5] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬 		[21] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[5] 2, 6, 8, 13, 127 💬
102 Ambrisentan [1] Ambrisentan[1] Ambrisentan 💬 [1] EDNRA 💬 [7] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Pathways in cancer, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[8] 51, 66, 84, 85, 86, 88, 210, 211 💬
103 Ambroxol [2] Ambroxol; Ambroxol hydrochloride[2] Ambroxol hydrochloride ,
Ambroxol 💬 		--[3] 2, 6, 19 💬
104 AMG 108 [1] AMG 108---[1] 46 💬
105 Amifampridine [2] Amifampridine; Amifampridine phosphate[2] Amifampridine ,
Amifampridine phosphate 💬 		[4] KCNA4,
KCNC3,
KCND2,
KCND3 💬 		[4] Cortisol synthesis and secretion, Cushing syndrome, Serotonergic synapse, Spinocerebellar ataxia 💬[3] 3, 11, 12 💬
106 Amifostine [2] Amifostine; Amifostine trihydrate[1] Amifostine 💬 --[2] 28, 63 💬
107 Amikacin [2] Amikacin; Amikacin sulfate[2] Amikacin sulfate ,
Amikacin 💬 		--[2] 60, 299 💬
108 Amiloride [2] Amiloride; Amiloride hydrochloride[2] Amiloride hydrochloride ,
Amiloride 💬 		[3] SCNN1A,
SCNN1B,
SCNN1G 💬 		[2] Aldosterone-regulated sodium reabsorption, Taste transduction 💬[4] 13, 67, 225, 299 💬
109 Amino acids [1] Amino acids---[4] 6, 70, 90, 298 💬
110 Aminocaproic acid [2] Aminocaproic acid; Eaca[1] Aminocaproic acid 💬 [2] PLAT,
PLG 💬 		[8] Apelin signaling pathway, Complement and coagulation cascades, Fluid shear stress and atherosclerosis, Influenza A, Neuroactive ligand-receptor interaction, Prostate cancer, Staphylococcus aureus infection, Transcriptional misregulation in cancer 💬[1] 70 💬
111 Aminohippuric acid [1] Aminohippurate[2] Aminohippurate sodium ,
Aminohippuric acid 💬 		--[2] 67, 86 💬
112 Aminolevulinic acid [2] 5-ALA; Aminolevulinic acid[2] Aminolevulinic acid hydrochloride ,
Aminolevulinic acid 💬 		--[4] 34, 54, 180, 286 💬
113 Aminophylline [1] Aminophylline[2] Aminophylline ,
Aminophylline dihydrate 💬 		[18] ADORA1,
ADORA2B,
PDE1,
PDE1,
PDE1,
PDE10,
PDE11,
PDE2A,
PDE3A,
PDE3B,
PDE4,
PDE4,
PDE4,
PDE4,
PDE7,
PDE7,
PDE8,
PDE8 💬 		[23] Alcoholism, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Cortisol synthesis and secretion, Cushing syndrome, Glucagon signaling pathway, Insulin signaling pathway, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Progesterone-mediated oocyte maturation, Purine metabolism, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Taste transduction, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 63 💬
114 Aminosalicylic acid [1] Aminosalicylic acid[1] Aminosalicylic acid 💬 --[3] 34, 96, 97 💬
115 Amiodarone [1] Amiodarone[2] Amiodarone hydrochloride ,
Amiodarone 💬 		[16] ADRA1A,
ADRA1B,
ADRA1D,
ADRB1,
KCND3,
KCNJ11,
KCNJ12_18,
KCNJ3,
KCNJ5,
KCNJ8,
KCNQ1,
SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬 		[34] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Dilated cardiomyopathy, Dopaminergic synapse, Estrogen signaling pathway, Gap junction, Gastric acid secretion, Glutamatergic synapse, GnRH secretion, Hormone signaling, Insulin secretion, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Oxytocin signaling pathway, Pancreatic secretion, Protein digestion and absorption, Regulation of lipolysis in adipocytes, Renin secretion, Retrograde endocannabinoid signaling, Salivary secretion, Serotonergic synapse, Spinocerebellar ataxia, Taste transduction, Type II diabetes mellitus, Vascular smooth muscle contraction, Vibrio cholerae infection, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 127 💬
116 Amiselimod [1] Amiselimod[1] Amiselimod 💬 [5] S1PR1,
S1PR2,
S1PR3,
S1PR4,
S1PR5 💬 		[4] Efferocytosis, FoxO signaling pathway, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway 💬[1] 97 💬
117 Amitriptyline [2] Amitriptyline; Amitriptyline hydrochloride[2] Amitriptyline hydrochloride ,
Amitriptyline 💬 		[2] SLC6A2,
SLC6A4 💬 		[3] Neuroactive ligand signaling, Serotonergic synapse, Synaptic vesicle cycle 💬[3] 97, 226, 299 💬
118 Amlitelimab [1] Amlitelimab[1] Amlitelimab 💬 [1] TNFSF4 💬 [1] Cytokine-cytokine receptor interaction 💬[1] 51 💬
119 Amlodipine [1] Amlodipine[4] Amlodipine besylate ,
Amlodipine maleate ,
Amlodipine ,
Amlodipine benzoate 💬 		[4] CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S 💬 		[37] Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[3] 51, 67, 298 💬
120 Ammonia [1] Ammonia[1] Ammonia solution, strong 💬 --[3] 88, 251, 296 💬
121 Ammonium chloride [1] Ammonium chloride[1] Ammonium chloride 💬 --[1] 251 💬
122 Amniotic Epithelial Cells [1] Amniotic epithelial cells---[1] 26 💬
123 Amoxapine [0] [1] Amoxapine 💬 [2] SLC6A2,
SLC6A4 💬 		[3] Neuroactive ligand signaling, Serotonergic synapse, Synaptic vesicle cycle 💬[1] 46 💬
124 Amoxicillin [2] Amoxicilina; Amoxicillin[3] Amoxicillin ,
Amoxicillin sodium ,
Amoxicillin 💬 		--[6] 19, 46, 63, 96, 97, 299 💬
125 Amphotericin B [1] Amphotericin B[1] Amphotericin B 💬 --[1] 299 💬
126 Ampicillin [1] Abpc[3] Ampicillin ,
Ampicillin hydrate ,
Ampicillin sodium 💬 		--[4] 2, 6, 84, 299 💬
127 Ampreloxetine [1] Ampreloxetine[1] Ampreloxetine 💬 [2] SLC6A2,
SLC6A4 💬 		[3] Neuroactive ligand signaling, Serotonergic synapse, Synaptic vesicle cycle 💬[2] 6, 17 💬
128 Amprenavir [1] Amprenavir[1] Amprenavir 💬 --[1] 265 💬
129 AMT-101 [1] AMT-101---[2] 46, 97 💬
130 AMT-130 [2] AMT-130; RAAV5-mihtt---[1] 8 💬
131 AMT-162 [1] AMT-162---[1] 2 💬
132 Amyl Nitrite [0] [1] Amyl nitrite 💬 [3] GUCY1A,
GUCY1A,
GUCY1B 💬 		[10] Circadian entrainment, Gap junction, Long-term depression, Oxytocin signaling pathway, Platelet activation, Purine metabolism, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 58 💬
133 AMZ002 [1] AMZ002---[1] 145 💬
134 Anacetrapib [1] Anacetrapib[1] Anacetrapib 💬 [1] CETP 💬 [1] Cholesterol metabolism 💬[1] 79 💬
135 Anakinra [1] Anakinra[1] Anakinra 💬 [2] IL1R1,
IL1R2 💬 		[15] Amoebiasis, Cytokine-cytokine receptor interaction, Fluid shear stress and atherosclerosis, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Inflammatory mediator regulation of TRP channels, MAPK signaling pathway, NF-kappa B signaling pathway, Osteoclast differentiation, Pathogenic Escherichia coli infection, Prostate cancer, Shigellosis, Th17 cell differentiation, Transcriptional misregulation in cancer 💬[19] 2, 13, 15, 19, 28, 37, 41, 46, 49, 50, 54, 56, 84, 86, 97, 106, 107, 266, 299 💬
136 Anastrozole [1] Anastrozole[1] Anastrozole 💬 [1] CYP19A 💬 [2] Ovarian steroidogenesis, Steroid hormone biosynthesis 💬[3] 78, 86, 193 💬
137 Andecaliximab [1] Andecaliximab[1] Andecaliximab 💬 [1] MMP9 💬 [15] Bladder cancer, Diabetic cardiomyopathy, Estrogen signaling pathway, Fluid shear stress and atherosclerosis, Hepatitis B, IL-17 signaling pathway, Leukocyte transendothelial migration, Lipid and atherosclerosis, MicroRNAs in cancer, Pathways in cancer, Prostate cancer, Proteoglycans in cancer, Relaxin signaling pathway, TNF signaling pathway, Transcriptional misregulation in cancer 💬[5] 46, 96, 97, 272, 299 💬
138 Andrographolide [1] Andrographolide---[1] 97 💬
139 Anemarrhena asphodeloides root [1] Zhimu[1] Anemarrhena rhizome 💬 --[1] 46 💬
140 Anfibatide [1] Anfibatide---[1] 64 💬
141 Angiotensin II [2] Angiotensin; Angiotensin II[3] Angiotensin II ,
Angiotensin II ,
Angiotensin II acetate 💬 		[2] AGTR1,
AGTR2 💬 		[17] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Hormone signaling, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[7] 17, 46, 49, 66, 218, 222, 224 💬
142 Anifrolumab [1] Anifrolumab[1] Anifrolumab 💬 [2] IFNAR1,
IFNAR2 💬 		[18] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Measles, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Osteoclast differentiation, PI3K-Akt signaling pathway, Pathways in cancer, Toll-like receptor signaling pathway 💬[5] 46, 49, 50, 51, 53 💬
143 Anitocabtagene autoleucel [1] Anito-CEL---[1] 11 💬
144 Anlotinib [1] Anlotinib[1] Catequentinib 💬 [10] FGFR1,
FGFR2,
FGFR3,
FGFR4,
FLT1,
FLT4,
KDR,
KIT,
PDGFRA,
PDGFRB 💬 		[36] Acute myeloid leukemia, Adherens junction, Bladder cancer, Breast cancer, Calcium signaling pathway, Central carbon metabolism in cancer, Choline metabolism in cancer, Endocytosis, Fluid shear stress and atherosclerosis, Focal adhesion, Gap junction, Gastric cancer, Glioma, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, Human papillomavirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanogenesis, Melanoma, MicroRNAs in cancer, PI3K-Akt signaling pathway, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Rheumatoid arthritis, Signaling pathways regulating pluripotency of stem cells, Thermogenesis, Transcriptional misregulation in cancer, VEGF signaling pathway 💬[1] 85 💬
145 Anrukinzumab [1] Anrukinzumab[1] Anrukinzumab 💬 [1] IL13 💬 [8] Asthma, Cytokine-cytokine receptor interaction, Fc epsilon RI signaling pathway, IL-17 signaling pathway, Inflammatory bowel disease, JAK-STAT signaling pathway, Pathways in cancer, Th1 and Th2 cell differentiation 💬[1] 97 💬
146 Anti-inhibitor coagulant complex [1] Activated prothrombin complex concentrate[1] Human blood-coagulation factor eight inhibitor bypassing activity complex, dried 💬 --[1] 288 💬
147 Antihemophilic factor human [1] Human coagulation factor viii---[1] 288 💬
148 Antihemophilic factor, human recombinant [2] Octocog alfa; Rahf[1] Octocog alfa 💬 [1] F8 💬 [1] Complement and coagulation cascades 💬[1] 288 💬
149 Antilymphocyte immunoglobulin (horse) [3] ANTI-thymocyte globulin; Hatg; Horse ANTI-thymocyte globulin[1] Anti-human thymocyte immunoglobulin, equine 💬 --[3] 60, 285, 326 💬
150 Antithymocyte immunoglobulin (rabbit) [9] ANTI-thymocyte globulin; Antithymocyte immunoglobulin; Lapine T-lymphocyte immune globulin; Rabbit ANTI-human thymocyte immunoglobulin; Rabbit antithymocyte globulin; Rabbit ATG; Ratg; Thymoglobulin; Thymoglobuline[1] Anti-human thymocyte immunoglobulin, rabbit 💬 [11] CD2,
CD3D,
CD3E,
CD3G,
CD4,
CD5,
CD7,
CD8A,
CD8B,
IL2RA,
ITGAL 💬 		[31] Antigen processing and presentation, Cell adhesion molecules, Chagas disease, Cytokine-cytokine receptor interaction, Endocytosis, Epstein-Barr virus infection, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, Human immunodeficiency virus 1 infection, JAK-STAT signaling pathway, Leukocyte transendothelial migration, Malaria, Measles, Natural killer cell mediated cytotoxicity, Neutrophil extracellular trap formation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pathways in cancer, Primary immunodeficiency, Rap1 signaling pathway, Regulation of actin cytoskeleton, Rheumatoid arthritis, Staphylococcus aureus infection, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Viral life cycle - HIV-1, Viral myocarditis, Viral protein interaction with cytokine and cytokine receptor, Virion - Human immunodeficiency virus, Yersinia infection 💬[13] 13, 36, 49, 51, 60, 62, 65, 96, 283, 284, 285, 286, 326 💬
151 AOC 1001 [1] AOC 1001---[1] 113 💬
152 AP-101 [1] AP-101---[1] 2 💬
153 Apabetalone [1] Apabetalone[1] Apabetalone 💬 --[1] 86 💬
154 Apadamtase alfa [2] Apadamtase alfa; Radamts-13[2] Apadamtase alfa ,
Apadamtase alfa and cinaxadamtase alfa 💬 		[1] ADAMTS13 💬 [1] Platelet activation 💬[1] 64 💬
155 Apelin [1] Apelin---[1] 86 💬
156 Apigenin [1] Apigenin---[2] 46, 97 💬
157 Apitegromab [1] Apitegromab[1] Apitegromab 💬 [1] MSTN 💬 [1] Cytokine-cytokine receptor interaction 💬[1] 3 💬
158 Apixaban [1] Apixaban[1] Apixaban 💬 [1] F10 💬 [1] Complement and coagulation cascades 💬[4] 96, 97, 222, 279 💬
159 Aplindore [1] Aplindore[1] Aplindore fumarate 💬 [2] DRD2,
DRD3 💬 		[10] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 6 💬
160 Apomorphine [2] Apomorphine; Apomorphine hydrochloride[2] Apomorphine hydrochloride ,
Apomorphine 💬 		[2] DRD1,
DRD2 💬 		[13] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[3] 5, 6, 7 💬
161 Apple [0] ---[2] 58, 70 💬
162 Apraclonidine [0] [2] Apraclonidine hydrochloride ,
Apraclonidine 💬 		[3] ADRA2A,
ADRA2B,
ADRA2C 💬 		[4] Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬[1] 11 💬
163 Apratastat [1] Apratastat[1] Apratastat 💬 [2] ADAM17,
MMP13 💬 		[9] Alzheimer disease, Coronavirus disease - COVID-19, Efferocytosis, Epithelial cell signaling in Helicobacter pylori infection, IL-17 signaling pathway, Notch signaling pathway, Parathyroid hormone synthesis, secretion and action, Relaxin signaling pathway, TNF signaling pathway 💬[1] 46 💬
164 Apremilast [1] Apremilast[1] Apremilast 💬 [4] PDE4,
PDE4,
PDE4,
PDE4 💬 		[4] Morphine addiction, Parathyroid hormone synthesis, secretion and action, Purine metabolism, cAMP signaling pathway 💬[8] 36, 46, 50, 56, 97, 107, 162, 271 💬
165 Aprotinin [1] Aprotinin[1] Aprotinin 💬 --[1] 28 💬
166 AQX-1125 [1] AQX-1125---[1] 226 💬
167 AR-42 [1] AR-42---[1] 34 💬
168 Aramchol [1] Aramchol---[2] 94, 265 💬
169 Arbaclofen [2] Arbaclofen; Baclofen[1] Arbaclofen 💬 [2] GABBR,
GABBR 💬 		[8] Estrogen signaling pathway, GABAergic synapse, GnRH secretion, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Taste transduction, cAMP signaling pathway 💬[2] 13, 206 💬
170 Arbaclofen Placarbil [1] Arbaclofen placarbil[1] Arbaclofen placarbil 💬 [2] GABBR,
GABBR 💬 		[8] Estrogen signaling pathway, GABAergic synapse, GnRH secretion, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Taste transduction, cAMP signaling pathway 💬[1] 13 💬
171 ARCT-810 [1] ARCT-810---[1] 251 💬
172 Arginine [1] Arginine[3] Arginine hydrochloride ,
Arginine ,
Arginine hydrochloride 💬 		--[5] 21, 65, 72, 225, 251 💬
173 ARGX-119 [1] ARGX-119---[2] 2, 12 💬
174 Arimoclomol [2] Arimoclomol; Arimoclomol citrate[2] Arimoclomol ,
Arimoclomol citrate 💬 		--[3] 2, 15, 19 💬
175 Aripiprazole [1] Aripiprazole[1] Aripiprazole 💬 [4] DRD2,
DRD3,
HTR1,
HTR2 💬 		[14] Alcoholism, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Inflammatory mediator regulation of TRP channels, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Serotonergic synapse, Taste transduction, cAMP signaling pathway 💬[2] 6, 206 💬
176 Armodafinil [2] Armodafinil; Modafinil[1] Armodafinil 💬 [1] SLC6A3 💬 [8] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Neuroactive ligand signaling, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Synaptic vesicle cycle 💬[3] 6, 13, 84 💬
177 Artenimol [0] [1] Artenimol 💬 --[1] 49 💬
178 Artesunate [1] Artesunate[1] Artesunate 💬 --[5] 18, 66, 85, 86, 96 💬
179 Arundic acid [1] Arundic acid[1] Arundic acid 💬 --[1] 2 💬
180 Ascorbic acid [2] Ascorbic acid; Vitamin C[1] Ascorbic acid 💬 --[8] 10, 97, 192, 206, 210, 211, 212, 298 💬
181 Asfotase alfa [1] Asfotase alfa[1] Asfotase alfa 💬 [1] E3.1.3.1 💬 [2] Folate biosynthesis, Thiamine metabolism 💬[1] 172 💬
182 ASP-7317 [1] MA09-hrpe---[1] 301 💬
183 Aspergillus oryzae [1] Aspergillus oryzae---[1] 97 💬
184 Astaxanthin [1] Astaxanthin---[1] 2 💬
185 AstraZeneca COVID-19 Vaccine [1] Chadox1 NCOV-19---[3] 46, 51, 299 💬
186 AT2220 [1] AT2220---[1] 256 💬
187 AT845 [1] AT845---[1] 256 💬
188 Atacicept [2] Atacicept; TACI-FC5[1] Atacicept 💬 [2] TNFSF13,
TNFSF13B 💬 		[4] Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis 💬[5] 13, 46, 49, 66, 222 💬
189 Ataluren [1] Ataluren[1] Ataluren 💬 --[6] 19, 113, 140, 246, 299, 329 💬
190 Atazanavir [1] Atazanavir[2] Atazanavir sulfate ,
Atazanavir 💬 		--[1] 265 💬
191 Atenolol [1] Atenolol[1] Atenolol 💬 [1] ADRB1 💬 [13] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 167 💬
192 Atezolizumab [1] Atezolizumab[1] Atezolizumab 💬 [1] PDL1 💬 [2] Cell adhesion molecules, PD-L1 expression and PD-1 checkpoint pathway in cancer 💬[1] 85 💬
193 ATL-2502 [1] ATL-2502---[1] 97 💬
194 ATL1102 [1] ATL1102---[2] 13, 113 💬
195 Atogepant [1] Atogepant[1] Atogepant 💬 [1] CALCRL 💬 [2] Neuroactive ligand-receptor interaction, Vascular smooth muscle contraction 💬[1] 226 💬
196 Atomoxetine [2] Atomoxetina; Atomoxetine[2] Atomoxetine hydrochloride ,
Atomoxetine 💬 		[1] SLC6A2 💬 [2] Neuroactive ligand signaling, Synaptic vesicle cycle 💬[4] 6, 8, 13, 230 💬
197 Atorvastatin [2] Atorvastatin; Atorvastatin calcium[2] Atorvastatin calcium ,
Atorvastatin 💬 		[1] HMGCR 💬 [3] AMPK signaling pathway, Bile secretion, Terpenoid backbone biosynthesis 💬[20] 13, 22, 46, 49, 51, 58, 63, 67, 79, 84, 88, 93, 96, 97, 160, 225, 265, 271, 297, 299 💬
198 Atosiban [1] Atosiban[2] Atosiban ,
Atosiban acetate 💬 		[1] OXTR 💬 [5] Calcium signaling pathway, Hormone signaling, Neuroactive ligand-receptor interaction, Oxytocin signaling pathway, cAMP signaling pathway 💬[1] 118 💬
199 Atovaquone [1] Atovaquone[1] Atovaquone 💬 --[1] 61 💬
200 Atrasentan [1] Atrasentan[1] Atrasentan hydrochloride 💬 [1] EDNRA 💬 [7] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Pathways in cancer, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[3] 66, 218, 222 💬
201 Atropine [1] Atropina[2] Atropine ,
Atropine sulfate 💬 		[5] CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5 💬 		[14] Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬[1] 299 💬
202 ATX-01 [1] ATX-01---[1] 113 💬
203 ATYR-1940 [1] ATYR1940---[1] 113 💬
204 Autologous cord blood [1] Autologous umbilical cord blood---[2] 211, 294 💬
205 AV-101 [1] AV-101---[2] 6, 86 💬
206 Avacincaptad pegol [1] Avacincaptad pegol[1] Avacincaptad pegol sodium 💬 [1] C5 💬 [11] Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Regulation of actin cytoskeleton, Staphylococcus aureus infection, Systemic lupus erythematosus 💬[1] 301 💬
207 Avacopan [1] Avacopan[1] Avacopan 💬 [1] C5AR1 💬 [6] Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Staphylococcus aureus infection 💬[4] 43, 44, 66, 222 💬
208 Avalglucosidase alfa [2] Avalglucosidase alfa; Neogaa[1] Avalglucosidase alfa 💬 [1] GAA 💬 [3] Galactose metabolism, Lysosome, Starch and sucrose metabolism 💬[1] 256 💬
209 Avalotcagene ontaparvovec [3] Avalotcagene ontaparvovec; DTX301; Scaav8OTC---[1] 251 💬
210 Avatrombopag [2] Avatrombopag; Avatrombopag maleate[2] Avatrombopag ,
Avatrombopag maleate 💬 		[1] TPOR 💬 [3] Cytokine-cytokine receptor interaction, Hormone signaling, JAK-STAT signaling pathway 💬[2] 60, 63 💬
211 AVB-101 [1] AVB-101---[1] 127 💬
212 Avdoralimab [1] Avdoralimab---[1] 162 💬
213 Avenciguat [1] Avenciguat[1] Avenciguat 💬 [3] GUCY1A,
GUCY1A,
GUCY1B 💬 		[10] Circadian entrainment, Gap junction, Long-term depression, Oxytocin signaling pathway, Platelet activation, Purine metabolism, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 51 💬
214 Aviptadil [1] Aviptadil[1] Aviptadil 💬 --[4] 49, 51, 84, 86 💬
215 Avoralstat [2] Avoralstat; BCX4161---[1] 65 💬
216 AVR-RD-01 [1] AVR-RD-01---[1] 19 💬
217 AVR-RD-02 [1] AVR-RD-02---[1] 19 💬
218 Axatilimab [1] Axatilimab[1] Axatilimab 💬 [1] CSF1R 💬 [11] Acute myeloid leukemia, Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, MAPK signaling pathway, Osteoclast differentiation, PI3K-Akt signaling pathway, Pathways in cancer, Rap1 signaling pathway, Ras signaling pathway, Transcriptional misregulation in cancer, Viral protein interaction with cytokine and cytokine receptor 💬[1] 85 💬
219 Axitinib [1] Axitinib[1] Axitinib 💬 [3] FLT1,
FLT4,
KDR 💬 		[14] Breast cancer, Calcium signaling pathway, Fluid shear stress and atherosclerosis, Focal adhesion, HIF-1 signaling pathway, MAPK signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Rheumatoid arthritis, Transcriptional misregulation in cancer, VEGF signaling pathway 💬[1] 34 💬
220 AZ-3102 [1] AZ-3102---[1] 19 💬
221 Azacitidine [1] Azacitidine[1] Azacitidine 💬 [3] DNMT1,
DNMT3A,
DNMT3B 💬 		[3] Cysteine and methionine metabolism, Efferocytosis, MicroRNAs in cancer 💬[1] 34 💬
222 Azathioprine [2] Azathioprine; Azatioprina[2] Azathioprine ,
Azathioprine sodium 💬 		--[22] 6, 11, 13, 19, 35, 42, 43, 44, 45, 46, 49, 55, 63, 65, 66, 84, 85, 94, 95, 96, 97, 162 💬
223 Azilsartan medoxomil [1] Azilsartan[3] Azilsartan medoxomil ,
Azilsartan ,
Azilsartan kamedoxomil 💬 		[1] AGTR1 💬 [17] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Hormone signaling, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 66 💬
224 Azithromycin [3] Azithromycin; Azithromycin dihydrate; Azithromycin monohydrate[3] Azithromycin hydrate ,
Azithromycin ,
Azithromycin 💬 		--[7] 13, 84, 85, 96, 228, 299, 340 💬
225 Aztreonam [2] Aztreonam; Aztreonam lysine[2] Aztreonam ,
Aztreonam lysine 💬 		--[2] 228, 299 💬