Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank Drug (Description in trials) KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1 Zagociguat [1] Zagociguat[1] Zagociguat 💬 [3] GUCY1A1,
GUCY1A2,
GUCY1B1 💬 		[10] Circadian entrainment, Gap junction, Long-term depression, Oxytocin signaling pathway, Platelet activation, Purine metabolism, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 21 💬
2 Zalcitabine [1] Zalcitabine[1] Zalcitabine 💬 --[1] 25 💬
3 Zamicastat [1] ZAMICASTAT---[1] 86 💬
4 Zamtocabtagene autoleucel [1] Zamtocabtagene autoleucel---[2] 49, 51 💬
5 Zanubrutinib [1] Zanubrutinib[1] Zanubrutinib 💬 [1] BTK 💬 [7] B cell receptor signaling pathway, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, NF-kappa B signaling pathway, Osteoclast differentiation, Platelet activation, Primary immunodeficiency 💬[7] 13, 48, 61, 63, 222, 300, 331 💬
6 Zasocitinib [1] Zasocitinib[1] Zasocitinib 💬 [1] TYK2 💬 [17] Coronavirus disease, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Measles, NOD-like receptor signaling pathway, Necroptosis, Osteoclast differentiation, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis 💬[2] 96, 97 💬
7 Zatolmilast [1] Zatolmilast[1] Zatolmilast 💬 [1] PDE4D 💬 [4] Morphine addiction, Parathyroid hormone synthesis, secretion and action, Purine metabolism, cAMP signaling pathway 💬[1] 206 💬
8 Zeaxanthin [1] Zeaxanthin---[1] 164 💬
9 Zetomipzomib [1] Zetomipzomib[2] Zetomipzomib ,
Zetomipzomib maleate 💬 		[2] PSMB8,
PSMB9 💬 		[1] Proteasome 💬[1] 95 💬
10 Zibotentan [1] Zibotentan[1] Zibotentan 💬 [1] EDNRA 💬 [7] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Pathways in cancer, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 51 💬
11 Zidovudine [1] Zidovudine[1] Zidovudine 💬 --[6] 25, 26, 135, 265, 325, 331 💬
12 Zigakibart [1] Zigakibart[1] Zigakibart 💬 [1] TNFSF13 💬 [3] Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, Rheumatoid arthritis 💬[2] 66, 223 💬
13 Zileuton [1] Zileuton[1] Zileuton 💬 [1] ALOX5 💬 [6] Arachidonic acid metabolism, Efferocytosis, Fc epsilon RI signaling pathway, Ovarian steroidogenesis, Serotonergic synapse, Toxoplasmosis 💬[3] 85, 160, 164 💬
14 Zilganersen [1] Zilganersen---[1] 131 💬
15 Zilucoplan [1] Zilucoplan[2] Zilucoplan sodium ,
Zilucoplan 💬 		[1] C5 💬 [11] Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Regulation of actin cytoskeleton, Staphylococcus aureus infection, Systemic lupus erythematosus 💬[3] 2, 11, 62 💬
16 Zilurgisertib [1] Zilurgisertib[1] Zilurgisertib 💬 [1] ACVR1 💬 [5] Cytokine-cytokine receptor interaction, Fluid shear stress and atherosclerosis, Hormone signaling, Signaling pathways regulating pluripotency of stem cells, TGF-beta signaling pathway 💬[1] 272 💬
17 Zinc [1] Zinc---[7] 2, 56, 85, 171, 222, 223, 299 💬
18 Zinc acetate [2] Zinc acetate; ZINC ACETATE DIHYDRATE[1] Zinc acetate 💬 --[2] 171, 299 💬
19 Zinc chloride [1] Zinc chloride[1] Zinc chloride 💬 --[1] 223 💬
20 Zinc gluconate [1] ZINC GLUCONATE[1] Zinc gluconate 💬 --[2] 56, 171 💬
21 Zinc oxide [1] Zinc oxide[1] Zinc oxide 💬 --[1] 156 💬
22 Zinpentraxin alfa [2] Recombinant human Pentraxin-2; Zinpentraxin alfa[1] Zinpentraxin alfa 💬 --[1] 85 💬
23 Ziritaxestat [1] Ziritaxestat[1] Ziritaxestat 💬 [1] ENPP2 💬 [1] Ether lipid metabolism 💬[2] 51, 85 💬
24 Zodasiran [2] ARO-ANG3; Zodasiran---[1] 79 💬
25 Zoledronic acid [2] ZOLEDRONIC ACID; ZOLEDRONIC ACID MONOHYDRATE[5] Zoledronic acid ,
Zoledronate disodium ,
Zoledronate trisodium ,
Zoledronic acid ,
Zoledronic acid hemipentahydrate 💬 		[1] FDPS 💬 [3] Human T-cell leukemia virus 1 infection, Influenza A, Terpenoid backbone biosynthesis 💬[16] 5, 6, 13, 17, 46, 75, 77, 93, 95, 96, 97, 270, 274, 282, 299, 333 💬
26 Zolmitriptan [1] ZOLMITRIPTAN[1] Zolmitriptan 💬 [2] HTR1B,
HTR1D 💬 		[5] Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Serotonergic synapse, Taste transduction, cAMP signaling pathway 💬[1] 6 💬
27 Zolpidem [2] Zolpidem; Zolpidem Tartrate[2] Zolpidem tartrate ,
Zolpidem 💬 		[16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬 		[9] Cadherin signaling, GABAergic synapse, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[3] 5, 6, 46 💬
28 Zonisamide [1] Zonisamide[1] Zonisamide 💬 [9] CACNA1G,
CACNA1H,
CACNA1I,
SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN8A,
SCN9A 💬 		[13] Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Cadherin signaling, Calcium signaling pathway, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dopaminergic synapse, GnRH secretion, IgSF CAM signaling, MAPK signaling pathway, Taste transduction, Type II diabetes mellitus 💬[1] 6 💬
29 Zopiclone [1] Zopiclone[1] Zopiclone 💬 [16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬 		[9] Cadherin signaling, GABAergic synapse, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[1] 6 💬
30 Zorevunersen [1] Zorevunersen---[1] 140 💬
31 ZUBERITAMAB [1] ZUBERITAMAB---[2] 63, 222 💬
32 Zunsemetinib [1] Zunsemetinib[1] Zunsemetinib 💬 [1] MAPKAPK2 💬 [8] C-type lectin receptor signaling pathway, Cellular senescence, Efferocytosis, Kaposi sarcoma-associated herpesvirus infection, MAPK signaling pathway, Neurotrophin signaling pathway, VEGF signaling pathway, Viral carcinogenesis 💬[1] 46 💬
33 Zuretinol acetate [1] Zuretinol Acetate---[1] 90 💬