Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank Drug (Description in trials) KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1 D-glucose [1] D-glucose---[2] 86, 88 💬
2 D-Serine [1] D-serine---[1] 6 💬
3 Dabigatran [1] Dabigatran[1] Dabigatran 💬 [1] F2 💬 [8] Complement and coagulation cascades, Coronavirus disease - COVID-19, Neuroactive ligand-receptor interaction, Pathogenic Escherichia coli infection, Pathways in cancer, Phospholipase D signaling pathway, Platelet activation, Regulation of actin cytoskeleton 💬[5] 51, 75, 85, 91, 124 💬
4 Dabigatran etexilate [1] Dabigatran etexilate[2] Dabigatran etexilate mesylate ,
Dabigatran etexilate 💬 		[1] F2 💬 [8] Complement and coagulation cascades, Coronavirus disease - COVID-19, Neuroactive ligand-receptor interaction, Pathogenic Escherichia coli infection, Pathways in cancer, Phospholipase D signaling pathway, Platelet activation, Regulation of actin cytoskeleton 💬[2] 51, 75 💬
5 Dabocemagene autoficel [1] D-FI---[1] 36 💬
6 Dabrafenib [1] Dabrafenib[2] Dabrafenib ,
Dabrafenib mesylate 💬 		[1] BRAF 💬 [42] Acute myeloid leukemia, Alcoholism, Alzheimer disease, Bladder cancer, Breast cancer, Chemical carcinogenesis - reactive oxygen species, Chemokine signaling pathway, Chronic myeloid leukemia, Colorectal cancer, Cushing syndrome, Endometrial cancer, ErbB signaling pathway, Focal adhesion, FoxO signaling pathway, Gastric cancer, Glioma, Hepatitis B, Hepatitis C, Hepatocellular carcinoma, Insulin signaling pathway, Long-term depression, Long-term potentiation, MAPK signaling pathway, Melanoma, Natural killer cell mediated cytotoxicity, Neurotrophin signaling pathway, Non-small cell lung cancer, Pancreatic cancer, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Progesterone-mediated oocyte maturation, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Regulation of actin cytoskeleton, Renal cell carcinoma, Serotonergic synapse, Thyroid cancer, Vascular smooth muscle contraction, cAMP signaling pathway, mTOR signaling pathway 💬[1] 34 💬
7 Daclizumab [1] Daclizumab[1] Daclizumab 💬 [1] IL2RA 💬 [11] Cytokine-cytokine receptor interaction, Endocytosis, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, JAK-STAT signaling pathway, Measles, PI3K-Akt signaling pathway, Pathways in cancer, Th1 and Th2 cell differentiation, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[8] 13, 56, 60, 65, 97, 107, 283, 284 💬
8 Dalfampridine [5] 4-aminopyridine; 4-AP; Dalfampridine; Fampridina; Fampridine[1] Dalfampridine 💬 [4] KCNA4,
KCNC3,
KCND2,
KCND3 💬 		[4] Cortisol synthesis and secretion, Cushing syndrome, Serotonergic synapse, Spinocerebellar ataxia 💬[4] 3, 4, 13, 14 💬
9 Dalteparin [1] Dalteparin[1] Dalteparin sodium 💬 [1] SERPINC1 💬 [1] Complement and coagulation cascades 💬[1] 222 💬
10 Danazol [1] Danazol[1] Danazol 💬 [3] AR,
ESR1,
PGR 💬 		[12] Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Estrogen signaling pathway, Hormone signaling, Oocyte meiosis, Pathways in cancer, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Prostate cancer, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬[5] 60, 63, 64, 65, 285 💬
11 Danicopan [2] ACH-0144471; Danicopan[1] Danicopan 💬 [1] CFD 💬 [3] Complement and coagulation cascades, Coronavirus disease - COVID-19, Staphylococcus aureus infection 💬[2] 62, 222 💬
12 Dantrolene [2] Dantrolene; Dantrolene sodium[2] Dantrolene sodium ,
Dantrolene 💬 		--[2] 13, 233 💬
13 Dapagliflozin [1] Dapagliflozin[1] Dapagliflozin 💬 --[13] 6, 19, 28, 49, 66, 67, 86, 88, 97, 210, 215, 218, 222 💬
14 Dapirolizumab pegol [1] Dapirolizumab pegol---[2] 13, 49 💬
15 Dapsone [1] Dapsone[1] Dapsone 💬 --[5] 35, 42, 60, 84, 162 💬
16 Daratumumab [1] Daratumumab[1] Daratumumab 💬 [1] CD38 💬 [6] Calcium signaling pathway, Hematopoietic cell lineage, Nicotinate and nicotinamide metabolism, Oxytocin signaling pathway, Pancreatic secretion, Salivary secretion 💬[10] 13, 16, 28, 46, 48, 49, 60, 63, 288, 331 💬
17 Darifenacin [1] Darifenacin[2] Darifenacin hydrobromide ,
Darifenacin 💬 		[1] CHRM3 💬 [12] Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction 💬[3] 2, 13, 26 💬
18 Darunavir [1] Darunavir[3] Darunavir ,
Darunavir ethanolate ,
Darunavir propylene glycolate 💬 		--[1] 2 💬
19 Darvadstrocel [1] Darvadstrocel[1] Darvadstrocel 💬 --[1] 96 💬
20 Dasatinib [1] Dasatinib[2] Dasatinib ,
Dasatinib 💬 		[8] ABL1,
EPHA2,
FYN,
KIT,
LCK,
PDGFRB,
SRC,
YES1 💬 		[76] Acute myeloid leukemia, Adherens junction, Axon guidance, Bacterial invasion of epithelial cells, Bladder cancer, Breast cancer, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cell cycle, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Choline metabolism in cancer, Cholinergic synapse, Chronic myeloid leukemia, Endocytosis, Epithelial cell signaling in Helicobacter pylori infection, ErbB signaling pathway, Estrogen signaling pathway, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Focal adhesion, GABAergic synapse, Gap junction, Glioma, GnRH signaling pathway, Hematopoietic cell lineage, Hepatitis B, Herpes simplex virus 1 infection, Hormone signaling, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Inflammatory mediator regulation of TRP channels, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, MAPK signaling pathway, Melanogenesis, Melanoma, MicroRNAs in cancer, Mitophagy - animal, NF-kappa B signaling pathway, Natural killer cell mediated cytotoxicity, Neurotrophin signaling pathway, Neutrophil extracellular trap formation, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Phospholipase D signaling pathway, Platelet activation, Primary immunodeficiency, Prion disease, Prolactin signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis, Sphingolipid signaling pathway, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Thyroid hormone signaling pathway, Tight junction, Tuberculosis, VEGF signaling pathway, Viral carcinogenesis, Viral myocarditis, Yersinia infection 💬[2] 51, 85 💬
21 Davunetide [1] Davunetide[1] Davunetide 💬 --[3] 5, 7, 127 💬
22 Daxdilimab [1] Daxdilimab[1] Daxdilimab 💬 [1] LILR 💬 [2] B cell receptor signaling pathway, Osteoclast differentiation 💬[2] 49, 50 💬
23 Dazodalibep [1] Dazodalibep---[1] 53 💬
24 Dazucorilant [1] Dazucorilant[1] Dazucorilant 💬 [1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[1] 2 💬
25 Dazukibart [1] Dazukibart[1] Dazukibart 💬 [1] IFNB 💬 [28] Alcoholic liver disease, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Osteoclast differentiation, PI3K-Akt signaling pathway, RIG-I-like receptor signaling pathway, Shigellosis, TNF signaling pathway, Toll-like receptor signaling pathway, Tuberculosis, Yersinia infection 💬[1] 50 💬
26 DCR-PH1 [1] DCR-PH1---[1] 234 💬
27 Deanol [0] [1] Deanol 💬 --[1] 6 💬
28 Debamestrocel [1] Debamestrocel---[1] 2 💬
29 Decitabine [1] Decitabine[1] Decitabine 💬 [3] DNMT1,
DNMT3A,
DNMT3B 💬 		[3] Cysteine and methionine metabolism, Efferocytosis, MicroRNAs in cancer 💬[3] 13, 60, 63 💬
30 Deferasirox [1] Deferasirox[1] Deferasirox 💬 --[4] 54, 254, 284, 286 💬
31 Deferiprone [1] Deferiprone[1] Deferiprone 💬 --[7] 2, 6, 18, 121, 122, 139, 233 💬
32 Deferitazole [1] Deferitazole[1] Deferitazole 💬 --[1] 284 💬
33 Deferoxamine [1] Deferoxamine[3] Deferoxamine mesylate ,
Deferoxamine ,
Deferoxamine hydrochloride 💬 		--[2] 284, 286 💬
34 Deflazacort [1] Deflazacort[1] Deflazacort 💬 [1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[2] 30, 113 💬
35 Delandistrogene moxeparvovec [1] Delandistrogene moxeparvovec[1] Delandistrogene moxeparvovec 💬 [1] DMD 💬 [5] Arrhythmogenic right ventricular cardiomyopathy, Cytoskeleton in muscle cells, Dilated cardiomyopathy, Hypertrophic cardiomyopathy, Viral myocarditis 💬[1] 113 💬
36 Delgocitinib [1] Delgocitinib[1] Delgocitinib 💬 [4] JAK1,
JAK2,
JAK3,
TYK2 💬 		[39] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease - COVID-19, Efferocytosis, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Hormone signaling, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Necroptosis, Non-small cell lung cancer, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Primary immunodeficiency, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬[1] 50 💬
37 Denosumab [1] Denosumab[1] Denosumab 💬 [1] TNFSF11 💬 [8] Breast cancer, Chemical carcinogenesis - receptor activation, Cytokine-cytokine receptor interaction, NF-kappa B signaling pathway, Osteoclast differentiation, Parathyroid hormone synthesis, secretion and action, Prolactin signaling pathway, Rheumatoid arthritis 💬[10] 46, 50, 70, 75, 77, 93, 95, 96, 274, 299 💬
38 Denufosol [1] Denufosol[1] Denufosol tetrasodium 💬 [1] P2RY2 💬 [4] Efferocytosis, Inflammatory mediator regulation of TRP channels, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction 💬[1] 299 💬
39 Deoxycholic acid [1] Deoxycholic acid[1] Deoxycholic acid 💬 --[1] 34 💬
40 Depelestat [2] Depelestat; DX-890[1] Depelestat 💬 [1] ELANE 💬 [3] Neutrophil extracellular trap formation, Systemic lupus erythematosus, Transcriptional misregulation in cancer 💬[1] 299 💬
41 Depemokimab [1] Depemokimab[1] Depemokimab 💬 [1] IL5 💬 [13] Allograft rejection, Asthma, Autoimmune thyroid disease, Cytokine-cytokine receptor interaction, Fc epsilon RI signaling pathway, Hematopoietic cell lineage, IL-17 signaling pathway, Inflammatory bowel disease, Intestinal immune network for IgA production, JAK-STAT signaling pathway, Pathways in cancer, T cell receptor signaling pathway, Th1 and Th2 cell differentiation 💬[2] 44, 45 💬
42 Dersalazine [1] Dersalazine sodium---[1] 97 💬
43 Dersimelagon [1] Dersimelagon[1] Dersimelagon 💬 [1] MC1R 💬 [3] Hormone signaling, Melanogenesis, Neuroactive ligand-receptor interaction 💬[2] 51, 254 💬
44 Desflurane [1] Desflurane[1] Desflurane 💬 --[2] 22, 296 💬
45 Desipramine [1] Desipramine[2] Desipramine hydrochloride ,
Desipramine 💬 		[2] SLC6A2,
SLC6A4 💬 		[3] Neuroactive ligand signaling, Serotonergic synapse, Synaptic vesicle cycle 💬[1] 121 💬
46 Desloratadine [0] [1] Desloratadine 💬 [1] HRH1 💬 [4] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction 💬[1] 13 💬
47 Desmopressin [4] Ddavp; Desmopressin; Desmopressin acetate; Desmopressine[2] Desmopressin ,
Desmopressin acetate 💬 		[2] AVPR2,
F8 💬 		[5] Complement and coagulation cascades, Hormone signaling, Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vasopressin-regulated water reabsorption 💬[6] 6, 64, 72, 75, 225, 288 💬
48 Desogestrel [2] Desogestrel; Désogestrel[1] Desogestrel 💬 [2] ESR1,
PGR 💬 		[11] Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Estrogen signaling pathway, Hormone signaling, Oocyte meiosis, Pathways in cancer, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬[1] 230 💬
49 Desoxyribonuclease [1] Desoxyribonuclease---[1] 299 💬
50 Deucravacitinib [1] Deucravacitinib[1] Deucravacitinib 💬 [1] TYK2 💬 [17] Coronavirus disease - COVID-19, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Measles, NOD-like receptor signaling pathway, Necroptosis, Osteoclast differentiation, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis 💬[9] 36, 37, 49, 53, 84, 96, 97, 160, 269 💬
51 Deucrictibant [1] Deucrictibant[1] Deucrictibant 💬 [1] BDKRB2 💬 [10] Calcium signaling pathway, Chagas disease, Complement and coagulation cascades, Endocrine and other factor-regulated calcium reabsorption, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Pathways in cancer, Regulation of actin cytoskeleton, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[1] 65 💬
52 Deupirfenidone [1] Deupirfenidone[1] Deupirfenidone 💬 --[1] 85 💬
53 Deutetrabenazine [1] Deutetrabenazine[1] Deutetrabenazine 💬 [1] SLC18A1_2 💬 [8] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Neuroactive ligand signaling, Parkinson disease, Serotonergic synapse, Synaptic vesicle cycle 💬[1] 8 💬
54 Deutivacaftor [1] Deutivacaftor[1] Deutivacaftor 💬 [1] CFTR 💬 [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
55 Dexamethasone [2] Dexamethasone; Dexamethasone sodium phosphate[3] Dexamethasone ,
Dexamethasone sodium phosphate ,
Dexamethasone phosphate 💬 		[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[25] 13, 14, 16, 19, 28, 35, 53, 63, 64, 65, 70, 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 296, 299, 331 💬
56 Dexamethasone palmitate [1] Dexamethasone palmitate[1] Dexamethasone palmitate 💬 [1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[1] 63 💬
57 Dexchlorpheniramine [1] Dexchlorpheniramine[1] Dexchlorpheniramine 💬 [1] HRH1 💬 [4] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction 💬[1] 13 💬
58 Dexlansoprazole [1] Dexlansoprazole[2] Dexlansoprazole ,
Dexlansoprazole sesquihydrate 💬 		[2] ATP4A,
ATP4B 💬 		[3] Collecting duct acid secretion, Gastric acid secretion, Oxidative phosphorylation 💬[1] 98 💬
59 Dexmedetomidine [3] Dexmedetomidina; Dexmedetomidine; Dexmedetomidine hydrochloride[2] Dexmedetomidine ,
Dexmedetomidine hydrochloride 💬 		[3] ADRA2A,
ADRA2B,
ADRA2C 💬 		[4] Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬[15] 2, 4, 6, 21, 22, 34, 46, 70, 107, 113, 171, 212, 215, 226, 280 💬
60 Dexpramipexole [1] Dexpramipexole[1] Dexpramipexole 💬 [5] DRD1,
DRD2,
DRD3,
DRD4,
DRD5 💬 		[13] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 2 💬
61 Dexrazoxane [1] Dexrazoxane[2] Dexrazoxane ,
Dexrazoxane hydrochloride 💬 		--[1] 13 💬
62 Dextran [2] Dextran; Dextran sulfate sodium[5] Dextran 1 ,
Dextran sulfate sodium ,
Dextran 40 ,
Dextran 70 ,
Dextran 75 💬 		[2] LIPC,
LPL 💬 		[4] Alzheimer disease, Cholesterol metabolism, Glycerolipid metabolism, PPAR signaling pathway 💬[3] 2, 79, 97 💬
63 Dextran 1 [0] ---[1] 97 💬
64 Dextromethorphan [2] Dextromethorphan; Dextromethorphan hydrobromide[3] Dextromethorphan hydrobromide ,
Dextromethorphan ,
Daunorubicin 💬 		[6] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D,
SIGMAR1 💬 		[21] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[10] 2, 6, 8, 13, 21, 46, 85, 96, 97, 156 💬
65 Dextrose, unspecified form [2] Dextrose; Glucose[2] Dextrose ,
Glucose, liquid 💬 		--[16] 6, 13, 50, 56, 60, 65, 66, 77, 96, 97, 168, 201, 226, 254, 257, 299 💬
66 Dezamizumab [1] Dezamizumab[1] Dezamizumab 💬 --[1] 28 💬
67 Dezocine [1] Dezocine[1] Dezocine 💬 [2] OPRK1,
OPRM1 💬 		[5] Estrogen signaling pathway, Hormone signaling, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction 💬[1] 46 💬
68 DFV890 [1] DFV890---[1] 106 💬
69 Diacerein [1] Diacerein[1] Diacerein 💬 --[2] 36, 46 💬
70 Diazepam [1] Diazepam[1] Diazepam 💬 [16] GABRA,
GABRA,
GABRA,
GABRA,
GABRA,
GABRA,
GABRB,
GABRB,
GABRB,
GABRD,
GABRE,
GABRG,
GABRG,
GABRG,
GABRP,
GABRQ 💬 		[8] GABAergic synapse, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[3] 46, 155, 298 💬
71 Diazoxide [2] Diazoxide; Diazoxide choline[2] Diazoxide ,
Diazoxide choline 💬 		[2] ABCC8,
KCNJ11 💬 		[4] ABC transporters, GnRH secretion, Insulin secretion, Type II diabetes mellitus 💬[2] 13, 193 💬
72 Dichloroacetic acid [1] Dichloroacetate[1] Sodium dichloroacetate 💬 [3] PDK2_3_4,
PDK2_3_4,
PDK2_3_4 💬 		[1] Diabetic cardiomyopathy 💬[2] 21, 86 💬
73 Dichloroisoproterenol [0] ---[2] 6, 299 💬
74 Diclofenac [2] Diclofenac; Diclofenac sodium[5] Diclofenac potassium ,
Diclofenac sodium ,
Diclofenac ,
Diclofenac diethylamine ,
Diclofenac epolamine 💬 		[2] PTGS1,
PTGS2 💬 		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Efferocytosis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[4] 13, 34, 46, 271 💬
75 Diclofenamide [1] Dichlorphenamide[1] Dichlorphenamide 💬 [13] CA,
CA,
CA,
CA,
CA,
CA,
CA,
CA,
CA,
CA,
CA,
CA2,
CA4 💬 		[6] Bile secretion, Collecting duct acid secretion, Gastric acid secretion, Nitrogen metabolism, Pancreatic secretion, Proximal tubule bicarbonate reclamation 💬[1] 114 💬
76 Dicloxacillin [1] Dicloxacillin[2] Dicloxacillin sodium ,
Dicloxacillin 💬 		--[1] 299 💬
77 Didanosine [1] Didanosine[1] Didanosine 💬 --[2] 25, 265 💬
78 Diethyl ether [1] Ether[1] Ether 💬 --[1] 235 💬
79 Diflunisal [1] Diflunisal[1] Diflunisal 💬 [1] PTGS2 💬 [22] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Efferocytosis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[1] 28 💬
80 Digitoxin [1] Digitoxin[1] Digitoxin 💬 [4] ATP1A,
ATP1A,
ATP1A,
ATP1A 💬 		[19] Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Aldosterone-regulated sodium reabsorption, Bile secretion, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cytoskeleton in muscle cells, Endocrine and other factor-regulated calcium reabsorption, Gastric acid secretion, Insulin secretion, Mineral absorption, Pancreatic secretion, Protein digestion and absorption, Proximal tubule bicarbonate reclamation, Salivary secretion, Thyroid hormone signaling pathway, Thyroid hormone synthesis, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 299 💬
81 Digoxin [1] Digoxin[1] Digoxin 💬 [4] ATP1A,
ATP1A,
ATP1A,
ATP1A 💬 		[19] Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Aldosterone-regulated sodium reabsorption, Bile secretion, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cytoskeleton in muscle cells, Endocrine and other factor-regulated calcium reabsorption, Gastric acid secretion, Insulin secretion, Mineral absorption, Pancreatic secretion, Protein digestion and absorption, Proximal tubule bicarbonate reclamation, Salivary secretion, Thyroid hormone signaling pathway, Thyroid hormone synthesis, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[3] 8, 46, 210 💬
82 Dihydrocodeine [0] [4] Dihydrocodeine phosphate ,
Dihydrocodeine bitartrate ,
Dihydrocodeine ,
Dihydrocodeine thiocyanate 💬 		[1] OPRM1 💬 [5] Estrogen signaling pathway, Hormone signaling, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction 💬[1] 310 💬
83 Dihydroergotoxine [0] [1] Dihydroergotoxine 💬 --[1] 6 💬
84 Diltiazem [2] Diltiazem; Diltiazem hydrochloride[3] Diltiazem hydrochloride ,
Diltiazem malate ,
Diltiazem 💬 		[4] CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S 💬 		[37] Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[4] 51, 58, 86, 88 💬
85 Dimercaprol [0] [1] Dimercaprol 💬 --[1] 13 💬
86 Dimethyl fumarate [2] Dimethyl fumarate; Dimethylfumarat[1] Dimethyl fumarate 💬 [1] KLHL19 💬 [6] Chemical carcinogenesis - reactive oxygen species, Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Parkinson disease, Pathways in cancer, Ubiquitin mediated proteolysis 💬[6] 13, 20, 49, 51, 86, 296 💬
87 Dimethyl sulfoxide [2] Dimethyl sulfoxide; Dmso[1] Dimethyl sulfoxide 💬 --[1] 226 💬
88 Dimethyltryptamine [0] ---[1] 13 💬
89 Diosmin [1] Diosmin[1] Diosmin 💬 --[4] 46, 51, 97, 265 💬
90 Diphenhydramine [2] Diphenhydramine; Diphenhydramine hydrochloride[4] Diphenhydramine ,
Diphenhydramine hydrochloride ,
Diphenhydramine salicylate ,
Diphenhydramine citrate 💬 		[1] HRH1 💬 [4] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction 💬[11] 11, 13, 19, 49, 51, 70, 86, 96, 222, 256, 300 💬
91 Dipivefrin [2] Dipivefrin; Dipivefrine[2] Dipivefrin hydrochloride ,
Dipivefrin 💬 		[9] ADRA1A,
ADRA1B,
ADRA1D,
ADRA2A,
ADRA2B,
ADRA2C,
ADRB1,
ADRB2,
ADRB3 💬 		[16] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 6 💬
92 Dipraglurant [1] Dipraglurant---[1] 6 💬
93 Dipyridamole [1] Dipyridamole[1] Dipyridamole 💬 [2] PDE4,
PDE5 💬 		[5] Morphine addiction, Parathyroid hormone synthesis, secretion and action, Purine metabolism, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[5] 46, 51, 66, 96, 224 💬
94 Diquafosol [1] Diquafosol[1] Diquafosol tetrasodium 💬 [1] P2RY2 💬 [4] Efferocytosis, Inflammatory mediator regulation of TRP channels, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction 💬[1] 53 💬
95 Diroximel fumarate [1] Diroximel fumarate[1] Diroximel fumarate 💬 --[1] 13 💬
96 Dirucotide [1] Dirucotide[1] Dirucotide 💬 --[1] 13 💬
97 Dithiopyr [1] Dimension---[1] 55 💬
98 Ditiocarb [1] Diethyldithiocarbamate---[1] 169 💬
99 Divozilimab [1] Divozilimab[1] Divozilimab 💬 [1] MS4A1 💬 [1] Hematopoietic cell lineage 💬[2] 13, 51 💬
100 DNL343 [1] DNL343---[1] 2 💬
101 Dobutamine [2] Dobutamin; Dobutamine[3] Dobutamine hydrochloride ,
Dobutamine ,
Dobutamine tartrate 💬 		[1] ADRB1 💬 [13] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[4] 57, 58, 86, 215 💬
102 Doconexent [1] Docosahexaenoic acid---[8] 6, 46, 49, 90, 94, 240, 299, 301 💬
103 Dolasetron [1] Dolasetron[2] Dolasetron mesylate ,
Dolasetron 💬 		[5] HTR3,
HTR3,
HTR3,
HTR3,
HTR3 💬 		[3] Neuroactive ligand signaling, Serotonergic synapse, Taste transduction 💬[1] 46 💬
104 Dolutegravir [1] Dolutegravir[2] Dolutegravir ,
Dolutegravir sodium 💬 		--[2] 2, 265 💬
105 Domagrozumab [1] PF-06252616[1] Domagrozumab 💬 [1] MSTN 💬 [1] Cytokine-cytokine receptor interaction 💬[1] 113 💬
106 Domperidone [1] Domperidone[2] Domperidone ,
Domperidone maleate 💬 		[1] DRD2 💬 [10] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[5] 6, 13, 17, 51, 230 💬
107 Donepezil [2] Donepezil; Donepezil hydrochloride[2] Donepezil hydrochloride ,
Donepezil 💬 		[1] ACHE 💬 [3] Cholinergic synapse, Glycerophospholipid metabolism, Neuroactive ligand signaling 💬[8] 5, 6, 13, 46, 124, 127, 156, 206 💬
108 Donidalorsen [1] Donidalorsen---[1] 65 💬
109 Dopamine [1] Dopamine[2] Dopamine hydrochloride ,
Dopamine 💬 		[5] DRD1,
DRD2,
DRD3,
DRD4,
DRD5 💬 		[13] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[4] 6, 7, 74, 77 💬
110 Dopastatin [1] Dopastatin---[1] 77 💬
111 Doravirine [1] Doravirine[1] Doravirine 💬 --[1] 265 💬
112 Doripenem [1] Doripenem hydrate[2] Doripenem hydrate ,
Doripenem 💬 		--[1] 299 💬
113 Dornase alfa [2] Dornase alfa; Dornase alpha[1] Dornase alfa 💬 --[2] 53, 299 💬
114 Dorzolamide [1] Dorzolamide[2] Dorzolamide hydrochloride ,
Dorzolamide 💬 		[13] CA,
CA,
CA,
CA,
CA,
CA,
CA,
CA,
CA,
CA,
CA,
CA2,
CA4 💬 		[6] Bile secretion, Collecting duct acid secretion, Gastric acid secretion, Nitrogen metabolism, Pancreatic secretion, Proximal tubule bicarbonate reclamation 💬[1] 90 💬
115 Dotatate [0] ---[1] 75 💬
116 Dotatate gallium Ga-68 [1] 68GA-dotatate[1] Edotreotide gallium Ga-68 💬 [1] SSTR2 💬 [5] Gastric acid secretion, Growth hormone synthesis, secretion and action, Hormone signaling, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[4] 19, 75, 84, 238 💬
117 Doxazosin [1] Doxazosin[2] Doxazosin mesylate ,
Doxazosin 💬 		[3] ADRA1A,
ADRA1B,
ADRA1D 💬 		[9] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 67 💬
118 Doxepin [0] [2] Doxepin hydrochloride ,
Doxepin 💬 		[3] HRH1,
SLC6A2,
SLC6A4 💬 		[6] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Serotonergic synapse, Synaptic vesicle cycle 💬[1] 6 💬
119 Doxorubicin [2] Doxorubicin; Doxorubicin hydrochloride[2] Doxorubicin hydrochloride ,
Doxorubicin 💬 		--[5] 26, 28, 34, 65, 331 💬
120 Doxycycline [4] Doxiciclina; Doxycyclin; Doxycycline; Doxycycline hyclate[5] Doxycycline ,
Doxycycline hyclate ,
Doxycycline calcium ,
Doxycycline ,
Doxycycline hydrochloride 💬 		--[15] 23, 28, 34, 46, 84, 89, 96, 97, 158, 161, 162, 167, 227, 280, 299 💬
121 DPCPX [0] ---[1] 299 💬
122 Drisapersen [1] Drisapersen[1] Drisapersen 💬 [1] DMD 💬 [5] Arrhythmogenic right ventricular cardiomyopathy, Cytoskeleton in muscle cells, Dilated cardiomyopathy, Hypertrophic cardiomyopathy, Viral myocarditis 💬[1] 113 💬
123 Dronabinol [3] Delta-9-tetrahydrocannabinol; Dronabinol; Tetrahydrocannabinol[1] Dronabinol 💬 [2] CNR1,
CNR2 💬 		[4] Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬[8] 2, 8, 13, 36, 46, 96, 271, 298 💬
124 Droxidopa [2] Droxidopa; L-dops[1] Droxidopa 💬 [9] ADRA1A,
ADRA1B,
ADRA1D,
ADRA2A,
ADRA2B,
ADRA2C,
ADRB1,
ADRB2,
ADRB3 💬 		[16] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[5] 5, 6, 17, 169, 170 💬
125 DS-2325a [1] DS-2325A---[1] 160 💬
126 DT-DEC01 [1] DT-DEC01---[1] 113 💬
127 Dulaglutide [0] [1] Dulaglutide 💬 [1] GLP1R 💬 [4] Hormone signaling, Insulin secretion, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[1] 299 💬
128 Duloxetine [2] Duloxetine; Duloxetine hydrochloride[2] Duloxetine hydrochloride ,
Duloxetine 💬 		[2] SLC6A2,
SLC6A4 💬 		[3] Neuroactive ligand signaling, Serotonergic synapse, Synaptic vesicle cycle 💬[2] 6, 13 💬
129 Dupilumab [1] Dupilumab[1] Dupilumab 💬 [1] IL4R 💬 [8] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, Inflammatory bowel disease, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer, Th1 and Th2 cell differentiation, Th17 cell differentiation 💬[5] 51, 97, 98, 160, 162 💬
130 Durvalumab [1] Durvalumab[1] Durvalumab 💬 [1] PDL1 💬 [2] Cell adhesion molecules, PD-L1 expression and PD-1 checkpoint pathway in cancer 💬[1] 85 💬
131 Dusquetide [1] Dusquetide[1] Dusquetide 💬 --[1] 56 💬
132 Dutasteride [2] Dutasterida; Dutasteride[1] Dutasteride 💬 [2] SRD5A1,
SRD5A2 💬 		[2] Prostate cancer, Steroid hormone biosynthesis 💬[2] 1, 2 💬
133 Duvoglustat [2] Duvoglustat; Duvoglustat hydrochloride[2] Duvoglustat ,
Duvoglustat hydrochloride 💬 		[1] GAA 💬 [3] Galactose metabolism, Lysosome, Starch and sucrose metabolism 💬[1] 256 💬
134 Dydrogesterone [1] Dydrogesterone[1] Dydrogesterone 💬 [1] PGR 💬 [5] Breast cancer, Chemical carcinogenesis - receptor activation, Estrogen signaling pathway, Oocyte meiosis, Progesterone-mediated oocyte maturation 💬[1] 13 💬
135 DYN-101 [1] DYN101---[1] 111 💬
136 DYNE-251 [1] DYNE-251---[1] 113 💬