Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank Drug (Description in trials) KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1 EA-2353 [1] EA-2353---[1] 90 💬
2 Ebselen [1] Ebselen---[1] 299 💬
3 Ecallantide [1] Ecallantide[1] Ecallantide 💬 [1] KLKB1 💬 [1] Complement and coagulation cascades 💬[1] 65 💬
4 Echinacea [1] Echinacea---[1] 97 💬
5 Eculizumab [1] ECULIZUMAB[1] Eculizumab 💬 [1] C5 💬 [11] Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Regulation of actin cytoskeleton, Staphylococcus aureus infection, Systemic lupus erythematosus 💬[8] 11, 13, 14, 61, 62, 109, 221, 223 💬
6 Edaravone [3] EDARAVONE; Methylphenylpyrazolone; Norphenazone[1] Edaravone 💬 --[3] 2, 6, 22 💬
7 Edasalonexent [1] EDASALONEXENT[1] Edasalonexent 💬 [1] RELA 💬 [76] AGE-RAGE signaling pathway in diabetic complications, Acute myeloid leukemia, Adipocytokine signaling pathway, Alcoholic liver disease, Alzheimer disease, Amoebiasis, Apoptosis, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Cadherin signaling, Cellular senescence, Chagas disease, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Chronic myeloid leukemia, Cocaine addiction, Coronavirus disease, Cytosolic DNA-sensing pathway, Diabetic cardiomyopathy, Epithelial cell signaling in Helicobacter pylori infection, Epstein-Barr virus infection, Fluid shear stress and atherosclerosis, HIF-1 signaling pathway, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Kaposi sarcoma-associated herpesvirus infection, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, Longevity regulating pathway, MAPK signaling pathway, Measles, Mitophagy - animal, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Neurotrophin signaling pathway, Neutrophil extracellular trap formation, Non-alcoholic fatty liver disease, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathogenic Escherichia coli infection, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Pertussis, Prolactin signaling pathway, Prostate cancer, RIG-I-like receptor signaling pathway, Ras signaling pathway, Relaxin signaling pathway, Salmonella infection, Shigellosis, Small cell lung cancer, Sphingolipid signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Transcriptional misregulation in cancer, Tuberculosis, Viral carcinogenesis, Yersinia infection, cAMP signaling pathway 💬[1] 113 💬
8 Edonerpic [1] Edonerpic---[1] 149 💬
9 Edoxaban [1] Edoxaban[3] Edoxaban tosilate hydrate ,
Edoxaban ,
Edoxaban tosylate 💬 		[1] F10 💬 [1] Complement and coagulation cascades 💬[4] 46, 71, 88, 222 💬
10 Edratide [1] Edratide[1] Edratide 💬 --[1] 49 💬
11 Efalizumab [1] EFALIZUMAB[1] Efalizumab 💬 [1] ITGAL 💬 [14] Cell adhesion molecule (CAM) interaction, Epstein-Barr virus infection, Human T-cell leukemia virus 1 infection, IgSF CAM signaling, Integrin signaling, Leukocyte transendothelial migration, Malaria, Natural killer cell mediated cytotoxicity, Neutrophil extracellular trap formation, Rap1 signaling pathway, Regulation of actin cytoskeleton, Rheumatoid arthritis, Staphylococcus aureus infection, Viral myocarditis 💬[10] 11, 13, 37, 46, 48, 53, 61, 95, 96, 221 💬
12 Efavaleukin alfa [1] EFAVALEUKIN ALFA[1] Efavaleukin alfa 💬 --[2] 49, 97 💬
13 Efavirenz [1] Efavirenz[1] Efavirenz 💬 --[3] 23, 67, 265 💬
14 Efgartigimod alfa [2] EFGARTIGIMOD; Efgartigimod alfa[1] Efgartigimod alfa 💬 --[7] 11, 13, 14, 35, 53, 63, 162 💬
15 Efmarodocokin alfa [1] Efmarodocokin alfa[1] Efmarodocokin alfa 💬 [1] IL22 💬 [4] Cytokine-cytokine receptor interaction, Inflammatory bowel disease, JAK-STAT signaling pathway, Th17 cell differentiation 💬[2] 96, 97 💬
16 Efzofitimod [1] Efzofitimod[1] Efzofitimod 💬 [2] HARS1,
HARS2 💬 		[1] Aminoacyl-tRNA biosynthesis 💬[2] 51, 84 💬
17 Egg [1] Egg---[2] 96, 310 💬
18 Egg white [1] Egg white---[1] 96 💬
19 Egg yolk [1] Egg yolk---[1] 310 💬
20 Elafibranor [1] Elafibranor[1] Elafibranor 💬 [1] PPARA 💬 [10] Adipocytokine signaling pathway, Alcoholic liver disease, Chemical carcinogenesis - receptor activation, Diabetic cardiomyopathy, Glucagon signaling pathway, Hepatitis C, Insulin resistance, Non-alcoholic fatty liver disease, PPAR signaling pathway, cAMP signaling pathway 💬[2] 93, 94 💬
21 Elafin [1] Elafin---[1] 86 💬
22 Elamipretide [1] Elamipretide[2] Elamipretide ,
Elamipretide hydrochloride 💬 		--[3] 18, 21, 324 💬
23 Elapegademase [2] Elapegademase; Elapegademase-lvlr[1] Elapegademase 💬 [1] ADA 💬 [2] Primary immunodeficiency, Purine metabolism 💬[1] 65 💬
24 Elasomeran [1] Elasomeran[1] Elasomeran 💬 --[1] 299 💬
25 Elbasvir [1] Elbasvir[1] Elbasvir 💬 --[1] 223 💬
26 Elcatonin [1] Elcatonin[1] Elcatonin 💬 [1] CALCR 💬 [3] Hormone signaling, Neuroactive ligand-receptor interaction, Osteoclast differentiation 💬[1] 70 💬
27 Eldecalcitol [1] Eldecalcitol[1] Eldecalcitol 💬 [1] VDR 💬 [5] Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬[1] 46 💬
28 Eleclazine [1] Eleclazine[1] Eleclazine 💬 [6] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN8A,
SCN9A 💬 		[5] Adrenergic signaling in cardiomyocytes, Cadherin signaling, Dopaminergic synapse, IgSF CAM signaling, Taste transduction 💬[1] 58 💬
29 Elexacaftor [1] ELEXACAFTOR[1] Elexacaftor 💬 [1] CFTR 💬 [9] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Phagocytosis, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
30 Elezanumab [1] Elezanumab[1] Elezanumab 💬 [1] RGMA 💬 [2] Axon guidance, TGF-beta signaling pathway 💬[1] 13 💬
31 Eliglustat [2] Eliglustat; ELIGLUSTAT TARTRATE[2] Eliglustat ,
Eliglustat tartrate 💬 		[1] UGCG 💬 [2] Cornified envelope formation, Sphingolipid metabolism 💬[1] 19 💬
32 Eliprodil [1] Eliprodil---[1] 6 💬
33 Elivaldogene autotemcel [1] Elivaldogene autotemcel[1] Elivaldogene autotemcel 💬 [1] ABCD1 💬 [2] ABC transporters, Peroxisome 💬[1] 20 💬
34 Elobixibat [1] Elobixibat[1] Elobixibat 💬 [1] SLC10A2 💬 [1] Bile secretion 💬[1] 6 💬
35 Elosulfase alfa [1] Elosulfase alfa[1] Elosulfase alfa 💬 [1] GALNS 💬 [2] Glycosaminoglycan degradation, Lysosome biogenesis 💬[1] 19 💬
36 Elotuzumab [1] Elotuzumab[1] Elotuzumab 💬 [1] SLAMF7 💬 [1] IgSF CAM signaling 💬[2] 28, 300 💬
37 Elranatamab [1] Elranatamab[1] Elranatamab 💬 [1] CD3E 💬 [11] Chagas disease, Epstein-Barr virus infection, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, Human immunodeficiency virus 1 infection, Measles, PD-L1 expression and PD-1 checkpoint pathway in cancer, Primary immunodeficiency, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation 💬[1] 28 💬
38 Elsubrutinib [1] ELSUBRUTINIB[1] Elsubrutinib 💬 [1] BTK 💬 [7] B cell receptor signaling pathway, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, NF-kappa B signaling pathway, Osteoclast differentiation, Platelet activation, Primary immunodeficiency 💬[1] 49 💬
39 Eltoprazine [2] ELTOPRAZINE; Eltoprazine Hydrochloride---[1] 6 💬
40 Eltrekibart [1] Eltrekibart[1] Eltrekibart 💬 [1] CXCR1 💬 [6] Chemokine signaling pathway, Cytokine-cytokine receptor interaction, Endocytosis, Epithelial cell signaling in Helicobacter pylori infection, Phospholipase D signaling pathway, Viral protein interaction with cytokine and cytokine receptor 💬[1] 97 💬
41 Eltrombopag [2] Eltrombopag; ELTROMBOPAG OLAMINE[2] Eltrombopag olamine ,
Eltrombopag choline 💬 		[1] MPL 💬 [3] Cytokine-cytokine receptor interaction, Hormone signaling, JAK-STAT signaling pathway 💬[5] 60, 63, 65, 284, 285 💬
42 ELX-02 [1] ELX-02---[3] 19, 218, 299 💬
43 Emapalumab [2] EMAPALUMAB; Emapalumab-Izsg[1] Emapalumab 💬 [1] IFNG 💬 [32] African trypanosomiasis, Allograft rejection, Amoebiasis, Antigen processing and presentation, Chagas disease, Cytokine-cytokine receptor interaction, Fluid shear stress and atherosclerosis, Graft-versus-host disease, HIF-1 signaling pathway, Hepatitis C, Herpes simplex virus 1 infection, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, JAK-STAT signaling pathway, Leishmaniasis, Malaria, Natural killer cell mediated cytotoxicity, Necroptosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways in cancer, Proteasome, Rheumatoid arthritis, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus 💬[6] 49, 50, 54, 60, 65, 107 💬
44 Emeramide [1] Emeramide---[2] 5, 17 💬
45 Emicizumab [1] Emicizumab[1] Emicizumab 💬 [2] F10,
F9 💬 		[1] Complement and coagulation cascades 💬[1] 288 💬
46 Emixustat [1] Emixustat[1] Emixustat 💬 --[1] 301 💬
47 Emodin [1] Emodin---[1] 67 💬
48 Empagliflozin [1] Empagliflozin[1] Empagliflozin 💬 --[17] 28, 46, 57, 58, 65, 67, 72, 77, 86, 96, 97, 113, 222, 223, 257, 298, 299 💬
49 Empasiprubart [1] Empasiprubart[1] Empasiprubart 💬 [1] C2 💬 [6] Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease, Pertussis, Staphylococcus aureus infection, Systemic lupus erythematosus 💬[3] 11, 14, 50 💬
50 Emtricitabine [1] Emtricitabine[1] Emtricitabine 💬 --[5] 13, 25, 93, 265, 325 💬
51 Enalapril [2] Enalapril; Enalapril Maleate[2] Enalapril maleate ,
Enalapril 💬 		[1] ACE 💬 [6] Chagas disease, Coronavirus disease, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬[10] 13, 19, 46, 57, 66, 113, 210, 222, 223, 279 💬
52 Enarodustat [1] Enarodustat[1] Enarodustat 💬 [3] EGLN1,
EGLN2,
EGLN3 💬 		[3] HIF-1 signaling pathway, Pathways in cancer, Renal cell carcinoma 💬[1] 60 💬
53 Enavogliflozin [1] Enavogliflozin[1] Enavogliflozin 💬 --[1] 58 💬
54 Encaleret [1] Encaleret[2] Encaleret ,
Encaleret sulfate 💬 		--[1] 235 💬
55 Endostatin [1] Endostatin---[1] 34 💬
56 Eneboparatide [1] Eneboparatide[1] Eneboparatide 💬 [1] PTH1R 💬 [4] Endocrine and other factor-regulated calcium reabsorption, Hormone signaling, Neuroactive ligand-receptor interaction, Parathyroid hormone synthesis, secretion and action 💬[1] 235 💬
57 Enfuvirtide [1] Enfuvirtide[1] Enfuvirtide 💬 --[2] 25, 265 💬
58 Enoxacin [1] Enoxacin[1] Enoxacin 💬 --[1] 2 💬
59 Enoxaparin [2] Enoxaparin; Enoxaparin Sodium[2] Enoxaparin sodium ,
Adomiparin 💬 		[1] SERPINC1 💬 [1] Complement and coagulation cascades 💬[6] 46, 48, 71, 222, 223, 327 💬
60 Enpatoran [1] Enpatoran[1] Enpatoran 💬 [2] TLR7,
TLR8 💬 		[6] Coronavirus disease, Influenza A, Lysosome biogenesis, Measles, Neutrophil extracellular trap formation, Toll-like receptor signaling pathway 💬[1] 49 💬
61 Ensifentrine [1] Ensifentrine[1] Ensifentrine 💬 [6] PDE3A,
PDE3B,
PDE4A,
PDE4B,
PDE4C,
PDE4D 💬 		[11] Apelin signaling pathway, Glucagon signaling pathway, Insulin signaling pathway, Morphine addiction, Parathyroid hormone synthesis, secretion and action, Progesterone-mediated oocyte maturation, Purine metabolism, Regulation of lipolysis in adipocytes, Renin secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 299 💬
62 Entacapone [2] ENTACAPONA; ENTACAPONE[1] Entacapone 💬 [1] COMT 💬 [3] Dopaminergic synapse, Steroid hormone biosynthesis, Tyrosine metabolism 💬[2] 6, 17 💬
63 Entecavir [1] Entecavir[2] Entecavir ,
Entecavir 💬 		--[8] 46, 56, 96, 97, 107, 222, 223, 271 💬
64 Enterococcus faecium [1] Enterococcus faecium---[1] 28 💬
65 ENTR-601-44 [1] ENTR-601-44---[1] 113 💬
66 Envudeucitinib [1] Envudeucitinib[1] Envudeucitinib 💬 [1] TYK2 💬 [17] Coronavirus disease, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Measles, NOD-like receptor signaling pathway, Necroptosis, Osteoclast differentiation, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis 💬[1] 49 💬
67 Enzastaurin [2] Enzastaurin; ENZASTAURIN HYDROCHLORIDE[2] Enzastaurin hydrochloride ,
Enzastaurin 💬 		[1] PRKCB 💬 [72] AGE-RAGE signaling pathway in diabetic complications, African trypanosomiasis, Aldosterone synthesis and secretion, Aldosterone-regulated sodium reabsorption, Amoebiasis, Amphetamine addiction, B cell receptor signaling pathway, Calcium signaling pathway, Carbohydrate digestion and absorption, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Choline metabolism in cancer, Cholinergic synapse, Circadian entrainment, Coronavirus disease, Diabetic cardiomyopathy, Dopaminergic synapse, Endocrine and other factor-regulated calcium reabsorption, ErbB signaling pathway, Fc gamma R-mediated phagosome formation, Focal adhesion, GABAergic synapse, Gap junction, Gastric acid secretion, Glioma, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatitis B, Hepatocellular carcinoma, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, IgSF CAM signaling, Inflammatory mediator regulation of TRP channels, Influenza A, Insulin resistance, Insulin secretion, Leishmaniasis, Leukocyte transendothelial migration, Long-term depression, Long-term potentiation, MAPK signaling pathway, Melanogenesis, MicroRNAs in cancer, Morphine addiction, NF-kappa B signaling pathway, Natural killer cell mediated cytotoxicity, Neuroactive ligand signaling, Neutrophil extracellular trap formation, Non-small cell lung cancer, Oxytocin signaling pathway, Pancreatic secretion, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phosphatidylinositol signaling system, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Retrograde endocannabinoid signaling, Salivary secretion, Serotonergic synapse, Sphingolipid signaling pathway, Spinocerebellar ataxia, Thyroid hormone signaling pathway, Thyroid hormone synthesis, VEGF signaling pathway, Vascular smooth muscle contraction, Wnt signaling pathway, mTOR signaling pathway 💬[1] 168 💬
68 Epalrestat [1] Epalrestat[1] Epalrestat 💬 [1] AKR1B1 💬 [5] Folate biosynthesis, Fructose and mannose metabolism, Galactose metabolism, Glycerolipid metabolism, Pentose and glucuronate interconversions 💬[1] 10 💬
69 Eperisone [1] EPERISONE[2] Eperisone hydrochloride ,
Eperisone 💬 		--[1] 2 💬
70 Ephedrine [2] Ephedrine; EPHEDRINE HYDROCHLORIDE[3] Ephedrine ,
Ephedrine hydrochloride ,
Ephedrine sulfate 💬 		[9] ADRA1A,
ADRA1B,
ADRA1D,
ADRA2A,
ADRA2B,
ADRA2C,
ADRB1,
ADRB2,
ADRB3 💬 		[16] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 11 💬
71 EPI-589 [1] EPI-589---[2] 2, 6 💬
72 Epicatechin [1] Epicatechin---[2] 86, 113 💬
73 Epigallocatechin [1] Epigallocatechin---[5] 8, 13, 28, 85, 113 💬
74 Epigallocatechin gallate [1] Epigallocatechin gallate---[1] 13 💬
75 Epinephrine [1] Epinephrine[3] Epinephrine ,
Epinephrine hydrochloride ,
Epinephrine bitartrate 💬 		[9] ADRA1A,
ADRA1B,
ADRA1D,
ADRA2A,
ADRA2B,
ADRA2C,
ADRB1,
ADRB2,
ADRB3 💬 		[16] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[4] 46, 70, 96, 97 💬
76 Eplerenone [1] Eplerenone[1] Eplerenone 💬 [1] NR3C2 💬 [1] Aldosterone-regulated sodium reabsorption 💬[5] 57, 75, 113, 210, 215 💬
77 Eplontersen [2] AKCEA-TTR-LRx; Eplontersen[1] Eplontersen sodium 💬 [1] TTR 💬 [1] Thyroid hormone synthesis 💬[1] 28 💬
78 Epoetin beta [2] Epoetin beta; NeoRecormon[1] Epoetin beta 💬 [1] EPOR 💬 [7] Cytokine-cytokine receptor interaction, Efferocytosis, Hematopoietic cell lineage, Hormone signaling, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer 💬[1] 13 💬
79 Epoprostenol [3] EPOPROSTENOL; EPOPROSTENOL SODIUM; Prostacyclin[2] Epoprostenol ,
Epoprostenol sodium 💬 		[1] PTGIR 💬 [3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 86 💬
80 Epratuzumab [1] EPRATUZUMAB[1] Epratuzumab 💬 [1] CD22 💬 [3] B cell receptor signaling pathway, Cell adhesion molecule (CAM) interaction, Hematopoietic cell lineage 💬[1] 49 💬
81 Eprotirome [1] Eprotirome---[1] 79 💬
82 Eptinezumab [1] Eptinezumab[1] Eptinezumab 💬 [1] CALCA 💬 [3] Hormone signaling, Neuroactive ligand-receptor interaction, Vascular smooth muscle contraction 💬[1] 226 💬
83 Equecabtagene autoleucel [1] Equecabtagene autoleucel---[1] 49 💬
84 ER2001 [1] ER2001---[1] 8 💬
85 Erenumab [1] Erenumab[1] Erenumab 💬 [1] CALCRL 💬 [2] Neuroactive ligand-receptor interaction, Vascular smooth muscle contraction 💬[1] 226 💬
86 Ergocalciferol [2] Ergocalciferol; Vitamin D 2[1] Ergocalciferol 💬 [1] VDR 💬 [5] Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬[5] 46, 84, 96, 97, 299 💬
87 Ergoloid mesylate [1] Ergoloid Mesylate[1] Ergoloid mesylates 💬 [6] ADRA1A,
ADRA1B,
ADRA1D,
ADRA2A,
ADRA2B,
ADRA2C 💬 		[9] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 206 💬
88 Erlotinib [1] Erlotinib[2] Erlotinib hydrochloride ,
Erlotinib 💬 		[1] EGFR 💬 [49] Adherens junction, Bladder cancer, Breast cancer, Cadherin signaling, Calcium signaling pathway, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Coronavirus disease, Cushing syndrome, Endocytosis, Endometrial cancer, Epithelial cell signaling in Helicobacter pylori infection, ErbB signaling pathway, Estrogen signaling pathway, Focal adhesion, FoxO signaling pathway, Gap junction, Gastric cancer, Glioma, GnRH signaling pathway, HIF-1 signaling pathway, Hepatitis C, Hepatocellular carcinoma, Human cytomegalovirus infection, Human papillomavirus infection, Integrin signaling, JAK-STAT signaling pathway, MAPK signaling pathway, Melanoma, MicroRNAs in cancer, Non-small cell lung cancer, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis, Virion - Hepatitis viruses 💬[2] 94, 160 💬
89 Erythromycin [1] Erythromycin[7] Erythromycin ,
Erythromycin estolate ,
Erythromycin ethylsuccinate ,
Erythromycin lactobionate ,
Erythromycin stearate ,
Erythromycin gluceptate ,
Erythromycin thiocyanate 💬 		--[6] 2, 6, 36, 164, 228, 291 💬
90 Erythropoietin [3] Epoetin alfa; Erythropoietin; RhEPO[4] Epoetin alfa ,
Epoetin epsilon ,
Epoetin theta ,
Epoetin zeta 💬 		[1] EPOR 💬 [7] Cytokine-cytokine receptor interaction, Efferocytosis, Hematopoietic cell lineage, Hormone signaling, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer 💬[11] 2, 6, 13, 18, 22, 47, 61, 63, 70, 95, 96 💬
91 Escherichia coli [1] Escherichia coli---[1] 53 💬
92 Escitalopram [3] Citalopram; Escitalopram; Escitalopram oxalate[2] Escitalopram oxalate ,
Escitalopram 💬 		[1] SLC6A4 💬 [3] Neuroactive ligand signaling, Serotonergic synapse, Synaptic vesicle cycle 💬[5] 2, 6, 13, 46, 77 💬
93 Esketamine [3] ESKETAMINE; ESKETAMINE HYDROCHLORIDE; KETAMINE[2] Esketamine ,
Esketamine hydrochloride 💬 		[5] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬 		[21] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[7] 2, 4, 6, 70, 96, 97, 156 💬
94 Esomeprazole [3] Esomeprazole; ESOMEPRAZOLE MAGNESIUM; Omeprazole[5] Esomeprazole magnesium ,
Esomeprazole sodium ,
Esomeprazole ,
Esomeprazole strontium ,
Esomeprazole magnesium dihydrate 💬 		[2] ATP4A,
ATP4B 💬 		[3] Collecting duct acid secretion, Gastric acid secretion, Oxidative phosphorylation 💬[10] 6, 13, 46, 86, 98, 107, 113, 234, 298, 299 💬
95 Estetrol [1] Estetrol[2] Estetrol ,
Estetrol 💬 		[2] ESR1,
ESR2 💬 		[10] Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Estrogen signaling pathway, GnRH secretion, Hormone signaling, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬[1] 53 💬
96 Estradiol [2] Estradiol; ESTRADIOL HEMIHYDRATE[2] Estradiol ,
Estradiol hemihydrate 💬 		[2] ESR1,
ESR2 💬 		[10] Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Estrogen signaling pathway, GnRH secretion, Hormone signaling, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬[9] 13, 46, 49, 65, 76, 78, 118, 226, 299 💬
97 Estradiol valerate [1] Estradiol valerate[1] Estradiol valerate 💬 [2] ESR1,
ESR2 💬 		[10] Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Estrogen signaling pathway, GnRH secretion, Hormone signaling, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬[1] 65 💬
98 Estriol [1] Estriol[2] Estriol ,
Estriol tripropionate 💬 		[2] ESR1,
ESR2 💬 		[10] Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Estrogen signaling pathway, GnRH secretion, Hormone signaling, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬[2] 13, 227 💬
99 Esuberaprost [1] Esuberaprost[2] Esuberaprost ,
Esuberaprost sodium 💬 		[1] PTGIR 💬 [3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 86 💬
100 Eszopiclone [2] Eszopiclone; Zopiclone[1] Eszopiclone 💬 [16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬 		[9] Cadherin signaling, GABAergic synapse, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[3] 6, 13, 46 💬
101 Etamsylate [1] ETAMSYLATE[1] Ethamsylate 💬 --[1] 227 💬
102 Etanercept [1] Etanercept[1] Etanercept 💬 [2] LTA,
TNF 💬 		[66] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[16] 15, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
103 Etentamig [1] Etentamig[1] Etentamig 💬 [2] CD3E,
TNFRSF17 💬 		[13] Chagas disease, Cytokine-cytokine receptor interaction, Epstein-Barr virus infection, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, Human immunodeficiency virus 1 infection, Intestinal immune network for IgA production, Measles, PD-L1 expression and PD-1 checkpoint pathway in cancer, Primary immunodeficiency, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation 💬[1] 28 💬
104 Eteplirsen [1] ETEPLIRSEN[1] Eteplirsen 💬 [1] DMD 💬 [5] Arrhythmogenic right ventricular cardiomyopathy, Cytoskeleton in muscle cells, Dilated cardiomyopathy, Hypertrophic cardiomyopathy, Viral myocarditis 💬[1] 113 💬
105 Ethambutol [1] Ethambutol[2] Ethambutol hydrochloride ,
Ethambutol 💬 		--[2] 84, 299 💬
106 Ethanol [1] Ethanol[2] Alcohol ,
Ethanol 💬 		--[8] 51, 58, 97, 144, 214, 278, 279, 280 💬
107 Ethanolamine [1] Ethanolamine[1] Monoethanolamine 💬 --[3] 60, 63, 279 💬
108 Ethanolamine oleate [1] Ethanolamine oleate[1] Ethanolamine oleate 💬 --[1] 279 💬
109 Ethinylestradiol [1] Ethinylestradiol[1] Ethinyl estradiol 💬 [1] ESR1 💬 [9] Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Estrogen signaling pathway, Hormone signaling, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬[2] 13, 118 💬
110 Etifoxine [1] Etifoxine[2] Etifoxine ,
Etifoxine hydrochloride 💬 		--[1] 13 💬
111 Etiprednol dicloacetate [1] Etiprednol dicloacetate[1] Etiprednol dicloacetate 💬 --[1] 96 💬
112 Etodolac [1] Etodolac[1] Etodolac 💬 [1] PTGS2 💬 [22] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Efferocytosis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[1] 46 💬
113 Etomidate [1] Etomidate[1] Etomidate 💬 [1] GABRA1 💬 [8] Cadherin signaling, GABAergic synapse, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Taste transduction 💬[2] 6, 11 💬
114 Etoposide [1] Etoposide[2] Etoposide ,
Etoposide phosphate 💬 		--[12] 11, 13, 14, 26, 28, 34, 54, 60, 65, 85, 164, 331 💬
115 Etoricoxib [1] Etoricoxib[1] Etoricoxib 💬 [1] PTGS2 💬 [22] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Efferocytosis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[5] 6, 46, 70, 165, 271 💬
116 Etrasimod [1] Etrasimod[2] Etrasimod ,
Etrasimod arginine 💬 		[3] S1PR1,
S1PR4,
S1PR5 💬 		[4] Efferocytosis, FoxO signaling pathway, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway 💬[3] 96, 97, 98 💬
117 Etravirine [2] ETRAVIRINA; Etravirine[1] Etravirine 💬 --[1] 18 💬
118 Etrolizumab [1] ETROLIZUMAB[1] Etrolizumab 💬 [1] ITGB7 💬 [13] Arrhythmogenic right ventricular cardiomyopathy, Cell adhesion molecule (CAM) interaction, Cytoskeleton in muscle cells, Dilated cardiomyopathy, ECM-receptor interaction, Focal adhesion, Human papillomavirus infection, Hypertrophic cardiomyopathy, Integrin signaling, Intestinal immune network for IgA production, PI3K-Akt signaling pathway, Regulation of actin cytoskeleton, Transcriptional misregulation in cancer 💬[2] 96, 97 💬
119 ETX101 [1] ETX101---[1] 140 💬
120 Eupatilin [1] Eupatilin---[2] 46, 271 💬
121 Everolimus [1] Everolimus[1] Everolimus 💬 [1] MTOR 💬 [52] AMPK signaling pathway, Acute myeloid leukemia, Adipocytokine signaling pathway, Alzheimer disease, Amyotrophic lateral sclerosis, Apelin signaling pathway, Autophagy - animal, Autophagy - other, Breast cancer, Cellular senescence, Central carbon metabolism in cancer, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Diabetic cardiomyopathy, ErbB signaling pathway, Gastric cancer, Glioma, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatocellular carcinoma, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Huntington disease, Insulin resistance, Insulin signaling pathway, Integrated stress response (ISR) signaling pathway, Integrin signaling, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Longevity regulating pathway, Longevity regulating pathway - multiple species, Lysosome biogenesis, MicroRNAs in cancer, Neutrophil extracellular trap formation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Shigellosis, Spinocerebellar ataxia, Th17 cell differentiation, Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus, mTOR signaling pathway 💬[12] 34, 67, 89, 96, 137, 157, 158, 228, 277, 278, 279, 280 💬
122 Evinacumab [1] EVINACUMAB[1] Evinacumab 💬 [1] ANGPTL3 💬 [1] Cholesterol metabolism 💬[1] 79 💬
123 Evobrutinib [1] Evobrutinib[1] Evobrutinib 💬 [1] BTK 💬 [7] B cell receptor signaling pathway, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, NF-kappa B signaling pathway, Osteoclast differentiation, Platelet activation, Primary immunodeficiency 💬[3] 13, 46, 49 💬
124 Evolocumab [1] Evolocumab[1] Evolocumab 💬 [1] PCSK9 💬 [1] Cholesterol metabolism 💬[2] 79, 222 💬
125 Exaluren [1] Exaluren---[1] 218 💬
126 Exametazime [1] Exametazime[1] Exametazime 💬 --[1] 6 💬
127 Exemestane [1] Exemestane[1] Exemestane 💬 [1] CYP19A1 💬 [2] Ovarian steroidogenesis, Steroid hormone biosynthesis 💬[1] 65 💬
128 Exenatide [1] Exenatide[1] Exenatide 💬 [1] GLP1R 💬 [4] Hormone signaling, Insulin secretion, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[6] 6, 17, 72, 78, 193, 233 💬
129 Exidavnemab [1] Exidavnemab---[2] 6, 17 💬
130 EXT608 [1] EXT608---[1] 235 💬
131 Ezetimibe [1] Ezetimibe[1] Ezetimibe 💬 [1] NPC1L1 💬 [1] Fat digestion and absorption 💬[5] 49, 79, 93, 149, 260 💬
132 Ezogabine [2] Ezogabine; RETIGABINE[1] Ezogabine 💬 [5] KCNQ1,
KCNQ2,
KCNQ3,
KCNQ4,
KCNQ5 💬 		[7] Adrenergic signaling in cardiomyocytes, Cholinergic synapse, Gastric acid secretion, IgSF CAM signaling, Pancreatic secretion, Protein digestion and absorption, Vibrio cholerae infection 💬[2] 2, 144 💬
133 Ezutromid [1] Ezutromid---[1] 113 💬