Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank Drug (Description in trials) KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1 Oat [1] Oat---[1] 46 💬
2 Obatoclax [1] Obatoclax[1] Obatoclax mesylate 💬 [1] BCL2 💬 [40] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Amyotrophic lateral sclerosis, Apoptosis, Apoptosis - multiple species, Autophagy - animal, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Colorectal cancer, Epstein-Barr virus infection, Estrogen signaling pathway, Fluid shear stress and atherosclerosis, Focal adhesion, Gastric cancer, HIF-1 signaling pathway, Hedgehog signaling pathway, Hepatitis B, Herpes simplex virus 1 infection, Human immunodeficiency virus 1 infection, JAK-STAT signaling pathway, Lipid and atherosclerosis, Measles, MicroRNAs in cancer, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Necroptosis, Neurotrophin signaling pathway, PI3K-Akt signaling pathway, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Prostate cancer, Protein processing in endoplasmic reticulum, Salmonella infection, Shigellosis, Small cell lung cancer, Sphingolipid signaling pathway, Toxoplasmosis, Tuberculosis, p53 signaling pathway 💬[1] 60 💬
3 Obecabtagene autoleucel [1] Obecabtagene autoleucel[1] Obecabtagene autoleucel 💬 [1] CD19 💬 [5] B cell receptor signaling pathway, Epstein-Barr virus infection, Hematopoietic cell lineage, PI3K-Akt signaling pathway, Primary immunodeficiency 💬[2] 13, 49 💬
4 Obefazimod [1] Obefazimod[1] Obefazimod 💬 [3] NCBP1,
NCBP2,
NCBP2L 💬 		[4] Amyotrophic lateral sclerosis, Nucleocytoplasmic transport, Spliceosome, mRNA surveillance pathway 💬[2] 96, 97 💬
5 Obeticholic acid [1] Obeticholic Acid[1] Obeticholic acid 💬 [1] NR1H4 💬 [1] Bile secretion 💬[3] 93, 265, 296 💬
6 Obexelimab [2] Obexelimab; XmAb5871[1] Obexelimab 💬 [1] CD19 💬 [5] B cell receptor signaling pathway, Epstein-Barr virus infection, Hematopoietic cell lineage, PI3K-Akt signaling pathway, Primary immunodeficiency 💬[4] 13, 49, 61, 300 💬
7 Obicetrapib [1] OBICETRAPIB[1] Obicetrapib 💬 [1] CETP 💬 [1] Cholesterol metabolism 💬[1] 79 💬
8 Obinutuzumab [1] OBINUTUZUMAB[1] Obinutuzumab 💬 [1] MS4A1 💬 [1] Hematopoietic cell lineage 💬[6] 43, 44, 49, 63, 222, 223 💬
9 Ocrelizumab [2] Ocrelizumab; RhuMAb 2H7[1] Ocrelizumab 💬 [1] MS4A1 💬 [1] Hematopoietic cell lineage 💬[4] 11, 13, 46, 49 💬
10 Octreotide [4] OCTREOTIDA; Octreotide; OCTREOTIDE ACETATE; OCTREOTIDE HYDROCHLORIDE[5] Octreotide ,
Octreotide acetate ,
Octreotide pamoate ,
Octreotide acetate ,
Octreotide hydrochloride 💬 		[1] SSTR2 💬 [5] Gastric acid secretion, Growth hormone synthesis, secretion and action, Hormone signaling, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[8] 67, 75, 77, 84, 85, 89, 193, 227 💬
11 OCU400 [1] OCU400---[1] 90 💬
12 OCU410ST [1] OCU410ST---[1] 301 💬
13 Odevixibat [1] Odevixibat[2] Odevixibat ,
Odevixibat hydrate 💬 		[1] SLC10A2 💬 [1] Bile secretion 💬[3] 296, 297, 338 💬
14 Odiparcil [1] Odiparcil---[1] 19 💬
15 Ofatumumab [2] HuMax-CD20; OFATUMUMAB[1] Ofatumumab 💬 [1] MS4A1 💬 [1] Hematopoietic cell lineage 💬[6] 11, 13, 35, 46, 222, 223 💬
16 Olanzapine [1] OLANZAPINE[2] Olanzapine ,
Olanzapine pamoate 💬 		[11] ADRA1A,
ADRA1B,
ADRA1D,
DRD2,
DRD3,
DRD4,
HRH1,
HTR2A,
HTR2B,
HTR2C,
HTR6 💬 		[18] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Alcoholism, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Inflammatory mediator regulation of TRP channels, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Salivary secretion, Serotonergic synapse, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[2] 2, 8 💬
17 Olaparib [1] Olaparib[1] Olaparib 💬 [2] PARP1,
PARP2 💬 		[5] Apoptosis, Base excision repair, Diabetic cardiomyopathy, NF-kappa B signaling pathway, Necroptosis 💬[2] 86, 285 💬
18 Oleic Acid [1] Oleic Acid[1] Oleic acid 💬 --[2] 13, 299 💬
19 Olenasufligene relduparvovec [2] LYS-SAF302; OLENASUFLIGENE RELDUPARVOVEC---[1] 19 💬
20 Olesoxime [1] Olesoxime[1] Olesoxime 💬 --[3] 2, 3, 13 💬
21 Oliceridine [1] Oliceridine[1] Oliceridine 💬 [3] ARRB1,
ARRB2,
OPRM1 💬 		[15] Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Dopaminergic synapse, Endocytosis, Estrogen signaling pathway, GnRH secretion, Hedgehog signaling pathway, Hormone signaling, MAPK signaling pathway, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Relaxin signaling pathway 💬[2] 46, 70 💬
22 Olipudase alfa [1] OLIPUDASE ALFA[1] Olipudase alfa 💬 [1] SMPD1 💬 [4] Lysosome biogenesis, Necroptosis, Sphingolipid metabolism, Sphingolipid signaling pathway 💬[1] 19 💬
23 Olive oil [1] Olive oil[1] Olive oil 💬 --[10] 13, 34, 35, 46, 49, 53, 97, 124, 162, 271 💬
24 Olmesartan [2] Olmesartan; Olmesartan medoxomil[2] Olmesartan medoxomil ,
Olmesartan 💬 		[1] AGTR1 💬 [17] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Hormone signaling, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[2] 57, 223 💬
25 Olokizumab [1] Olokizumab[1] Olokizumab 💬 [1] IL6 💬 [49] AGE-RAGE signaling pathway in diabetic complications, African trypanosomiasis, Alcoholic liver disease, Alzheimer disease, Amoebiasis, C-type lectin receptor signaling pathway, Cellular senescence, Chagas disease, Coronavirus disease, Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, Epstein-Barr virus infection, FoxO signaling pathway, Graft-versus-host disease, HIF-1 signaling pathway, Hematopoietic cell lineage, Hepatitis B, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Intestinal immune network for IgA production, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Legionellosis, Lipid and atherosclerosis, Malaria, Measles, NOD-like receptor signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Rheumatoid arthritis, Salmonella infection, TNF signaling pathway, Th17 cell differentiation, Toll-like receptor signaling pathway, Transcriptional misregulation in cancer, Tuberculosis, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection 💬[2] 46, 96 💬
26 Olsalazine [1] Olsalazine[2] Olsalazine sodium ,
Olsalazine 💬 		--[1] 271 💬
27 Omadacycline [1] Omadacycline[2] Omadacycline ,
Omadacycline tosylate 💬 		--[1] 299 💬
28 Omalizumab [1] Omalizumab[1] Omalizumab 💬 [1] FCER1A 💬 [4] Asthma, Fc epsilon RI signaling pathway, Phospholipase D signaling pathway, Sphingolipid signaling pathway 💬[7] 46, 53, 65, 98, 162, 226, 299 💬
29 Omaveloxolone [1] Omaveloxolone[1] Omaveloxolone 💬 [1] NFE2L2 💬 [7] Chemical carcinogenesis - reactive oxygen species, Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Lipid and atherosclerosis, Parkinson disease, Pathways in cancer, Protein processing in endoplasmic reticulum 💬[1] 18 💬
30 Omega-3 fatty acids [3] Omega 3 fatty acids; Omega-3; Omega-3 fatty acids---[4] 13, 49, 79, 223 💬
31 Omeprazole [3] Omeprazol; Omeprazole; OMEPRAZOLE MAGNESIUM[3] Omeprazole ,
Omeprazole sodium ,
Omeprazole magnesium 💬 		[2] ATP4A,
ATP4B 💬 		[3] Collecting duct acid secretion, Gastric acid secretion, Oxidative phosphorylation 💬[18] 6, 8, 13, 21, 46, 51, 67, 85, 90, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬
32 Omidubicel [1] Omidubicel[1] Omidubicel 💬 [1] CD34 💬 [2] Cell adhesion molecule (CAM) interaction, Hematopoietic cell lineage 💬[1] 60 💬
33 Omigapil [1] Omigapil---[1] 113 💬
34 OMS906 [1] OMS906---[2] 62, 223 💬
35 Onasemnogene abeparvovec [3] ONASEMNOGENE ABEPARVOVEC; Onasemnogene Abeparvovec-brve; Onasemnogene Abeparvovec-xioi[1] Onasemnogene abeparvovec 💬 --[1] 3 💬
36 Ondansetron [2] Ondansetron; Ondansetron hydrochloride dihydrate[2] Ondansetron ,
Ondansetron hydrochloride hydrate 💬 		[5] HTR3A,
HTR3B,
HTR3C,
HTR3D,
HTR3E 💬 		[3] Neuroactive ligand signaling, Serotonergic synapse, Taste transduction 💬[5] 6, 97, 98, 107, 231 💬
37 Ongericimab [1] Ongericimab---[1] 79 💬
38 Ontamalimab [1] Ontamalimab---[2] 96, 97 💬
39 Opicapone [1] OPICAPONE[1] Opicapone 💬 [1] COMT 💬 [3] Dopaminergic synapse, Steroid hormone biosynthesis, Tyrosine metabolism 💬[1] 6 💬
40 Opicinumab [1] Opicinumab[1] Opicinumab 💬 --[1] 13 💬
41 ORE-1001 [0] ---[1] 97 💬
42 Orelabrutinib [1] Orelabrutinib[1] Orelabrutinib 💬 [1] BTK 💬 [7] B cell receptor signaling pathway, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, NF-kappa B signaling pathway, Osteoclast differentiation, Platelet activation, Primary immunodeficiency 💬[5] 13, 49, 53, 61, 63 💬
43 Orilanolimab [1] ORILANOLIMAB[1] Orilanolimab 💬 --[1] 61 💬
44 ORM-12741 [1] ORM-12741---[1] 51 💬
45 Ornithine [1] Ornithine[2] Ornithine ,
Ornithine aspartate 💬 		--[3] 96, 245, 251 💬
46 Orvepitant [1] ORVEPITANT[1] Orvepitant 💬 [1] TACR1 💬 [3] Calcium signaling pathway, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction 💬[1] 85 💬
47 Oseltamivir [1] Oseltamivir[2] Oseltamivir phosphate ,
Oseltamivir 💬 		--[3] 63, 97, 299 💬
48 Osilodrostat [1] OSILODROSTAT[2] Osilodrostat ,
Osilodrostat phosphate 💬 		[1] CYP11B2 💬 [2] Aldosterone synthesis and secretion, Steroid hormone biosynthesis 💬[1] 75 💬
49 OSU-6162 [0] ---[2] 6, 8 💬
50 Otelixizumab [1] Otelixizumab[1] Otelixizumab 💬 [3] CD3D,
CD3E,
CD3G 💬 		[11] Chagas disease, Epstein-Barr virus infection, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, Human immunodeficiency virus 1 infection, Measles, PD-L1 expression and PD-1 checkpoint pathway in cancer, Primary immunodeficiency, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation 💬[1] 46 💬
51 Otilimab [1] OTILIMAB[1] Otilimab 💬 [1] CSF2 💬 [16] Acute myeloid leukemia, Amoebiasis, Coronavirus disease, Cytokine-cytokine receptor interaction, Fc epsilon RI signaling pathway, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, IL-17 signaling pathway, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Natural killer cell mediated cytotoxicity, Rheumatoid arthritis, Shigellosis, T cell receptor signaling pathway, TNF signaling pathway, Transcriptional misregulation in cancer 💬[1] 46 💬
52 OTL-203 [1] OTL-203---[1] 19 💬
53 Oxabact [2] Oxabact; Oxalobacter formigenes---[1] 234 💬
54 Oxaloacetic acid [1] Oxaloacetic Acid---[1] 2 💬
55 Oxandrolone [1] Oxandrolone[1] Oxandrolone 💬 [1] AR 💬 [4] Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬[2] 211, 285 💬
56 Oxatomide [1] Oxatomide[1] Oxatomide 💬 [1] ALOX5 💬 [6] Arachidonic acid metabolism, Efferocytosis, Fc epsilon RI signaling pathway, Ovarian steroidogenesis, Serotonergic synapse, Toxoplasmosis 💬[1] 113 💬
57 Oxcarbazepine [1] Oxcarbazepine[1] Oxcarbazepine 💬 [6] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN8A,
SCN9A 💬 		[5] Adrenergic signaling in cardiomyocytes, Cadherin signaling, Dopaminergic synapse, IgSF CAM signaling, Taste transduction 💬[1] 13 💬
58 Oxiconazole [1] Oxiconazole[2] Oxiconazole nitrate ,
Oxiconazole 💬 		--[1] 160 💬
59 Oxitriptan [2] 5-HTP; OXITRIPTAN[1] Oxitriptan 💬 --[1] 97 💬
60 Oxybuprocaine [1] Oxybuprocaine[2] Benoxinate hydrochloride ,
Oxybuprocaine 💬 		[6] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN8A,
SCN9A 💬 		[5] Adrenergic signaling in cardiomyocytes, Cadherin signaling, Dopaminergic synapse, IgSF CAM signaling, Taste transduction 💬[1] 6 💬
61 Oxybutynin [1] Oxybutynin[2] Oxybutynin ,
Oxybutynin chloride 💬 		[5] CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5 💬 		[14] Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬[3] 6, 13, 53 💬
62 Oxycodone [2] Oxycodone; OXYCODONE HYDROCHLORIDE[3] Oxycodone hydrochloride ,
Oxycodone terephthalate ,
Oxycodone 💬 		[3] OPRD1,
OPRK1,
OPRM1 💬 		[7] Estrogen signaling pathway, Hormone signaling, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[7] 6, 13, 46, 70, 226, 231, 298 💬
63 Oxygen [1] Oxygen[1] Oxygen 💬 --[30] 6, 13, 15, 19, 22, 36, 46, 49, 70, 71, 85, 86, 88, 90, 96, 97, 129, 149, 168, 193, 211, 226, 230, 235, 269, 271, 294, 298, 299, 330 💬
64 Oxymatrine [1] Oxymatrine---[1] 37 💬
65 Oxytocin [1] Oxytocin[1] Oxytocin 💬 [1] OXTR 💬 [5] Calcium signaling pathway, Hormone signaling, Neuroactive ligand-receptor interaction, Oxytocin signaling pathway, cAMP signaling pathway 💬[8] 6, 70, 72, 127, 168, 193, 206, 226 💬
66 Oyster [1] Oyster---[1] 84 💬
67 Ozanezumab [1] Ozanezumab[1] Ozanezumab 💬 [1] RTN4 💬 [1] Alzheimer disease 💬[1] 2 💬
68 Ozanimod [2] OZANIMOD; Ozanimod hydrochloride[2] Ozanimod hydrochloride ,
Ozanimod 💬 		[5] S1PR1,
S1PR2,
S1PR3,
S1PR4,
S1PR5 💬 		[4] Efferocytosis, FoxO signaling pathway, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway 💬[3] 13, 96, 97 💬
69 Ozone [1] Ozone---[5] 49, 51, 70, 71, 226 💬
70 Ozoralizumab [1] Ozoralizumab[1] Ozoralizumab 💬 [1] TNF 💬 [66] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[1] 46 💬