Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank Drug (Description in trials) KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1 Oat [1] OAT---[1] 46 💬
2 Obatoclax [1] Obatoclax[1] Obatoclax mesylate 💬 [1] BCL2 💬 [40] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Amyotrophic lateral sclerosis, Apoptosis, Apoptosis - multiple species, Autophagy - animal, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Colorectal cancer, Epstein-Barr virus infection, Estrogen signaling pathway, Fluid shear stress and atherosclerosis, Focal adhesion, Gastric cancer, HIF-1 signaling pathway, Hedgehog signaling pathway, Hepatitis B, Herpes simplex virus 1 infection, Human immunodeficiency virus 1 infection, JAK-STAT signaling pathway, Lipid and atherosclerosis, Measles, MicroRNAs in cancer, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Necroptosis, Neurotrophin signaling pathway, PI3K-Akt signaling pathway, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Prostate cancer, Protein processing in endoplasmic reticulum, Salmonella infection, Shigellosis, Small cell lung cancer, Sphingolipid signaling pathway, Toxoplasmosis, Tuberculosis, p53 signaling pathway 💬[1] 60 💬
3 Obecabtagene autoleucel [2] OBE-CEL; Obecabtagene autoleucel[1] Obecabtagene autoleucel 💬 [1] CD19 💬 [5] B cell receptor signaling pathway, Epstein-Barr virus infection, Hematopoietic cell lineage, PI3K-Akt signaling pathway, Primary immunodeficiency 💬[1] 49 💬
4 Obeticholic acid [2] 6-ecdca; Obeticholic acid[1] Obeticholic acid 💬 [1] NR1H4 💬 [1] Bile secretion 💬[3] 93, 265, 296 💬
5 Obexelimab [2] Obexelimab; XMAB5871[1] Obexelimab 💬 [1] CD19 💬 [5] B cell receptor signaling pathway, Epstein-Barr virus infection, Hematopoietic cell lineage, PI3K-Akt signaling pathway, Primary immunodeficiency 💬[4] 13, 49, 61, 300 💬
6 Obinutuzumab [1] Obinutuzumab[1] Obinutuzumab 💬 [1] MS4A1 💬 [1] Hematopoietic cell lineage 💬[5] 43, 44, 49, 63, 222 💬
7 Ocrelizumab [2] Ocrelizumab; Rhumab 2h7[1] Ocrelizumab 💬 [1] MS4A1 💬 [1] Hematopoietic cell lineage 💬[4] 11, 13, 46, 49 💬
8 Octreotide [3] Octreotida; Octreotide; Octreotide acetate[4] Octreotide ,
Octreotide acetate ,
Octreotide pamoate ,
Octreotide acetate 💬 		[1] SSTR2 💬 [5] Gastric acid secretion, Growth hormone synthesis, secretion and action, Hormone signaling, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[8] 67, 75, 77, 84, 85, 89, 193, 227 💬
9 OCU400 [1] OCU400---[1] 90 💬
10 OCU410ST [1] OCU410ST---[1] 301 💬
11 Odevixibat [1] Odevixibat[1] Odevixibat 💬 [1] SLC10A2 💬 [1] Bile secretion 💬[3] 296, 297, 338 💬
12 Odiparcil [1] Odiparcil---[1] 19 💬
13 Ofatumumab [2] Humax-CD20; Ofatumumab[1] Ofatumumab 💬 [1] MS4A1 💬 [1] Hematopoietic cell lineage 💬[4] 11, 13, 35, 46 💬
14 Olanzapine [1] Olanzapine[2] Olanzapine ,
Olanzapine pamoate 💬 		[11] ADRA1A,
ADRA1B,
ADRA1D,
DRD2,
DRD3,
DRD4,
HRH1,
HTR2,
HTR2,
HTR2,
HTR6 💬 		[18] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Alcoholism, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Inflammatory mediator regulation of TRP channels, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Salivary secretion, Serotonergic synapse, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[2] 2, 8 💬
15 Olaparib [1] Olaparib[1] Olaparib 💬 [2] PARP1,
PARP2 💬 		[5] Apoptosis, Base excision repair, Diabetic cardiomyopathy, NF-kappa B signaling pathway, Necroptosis 💬[2] 86, 285 💬
16 Olea europaea leaf [0] ---[3] 34, 49, 53 💬
17 Oleic Acid [0] [1] Oleic acid 💬 --[1] 299 💬
18 Olenasufligene relduparvovec [2] LYS-SAF302; Olenasufligene relduparvovec---[1] 19 💬
19 Olesoxime [1] Olesoxime[1] Olesoxime 💬 --[3] 2, 3, 13 💬
20 Olipudase alfa [1] Olipudase alfa[1] Olipudase alfa 💬 [1] SMPD1 💬 [4] Lysosome, Necroptosis, Sphingolipid metabolism, Sphingolipid signaling pathway 💬[1] 19 💬
21 Olive oil [1] Olive OIL[1] Olive oil 💬 --[3] 34, 49, 53 💬
22 Olokizumab [1] Olokizumab[1] Olokizumab 💬 [1] IL6 💬 [49] AGE-RAGE signaling pathway in diabetic complications, African trypanosomiasis, Alcoholic liver disease, Alzheimer disease, Amoebiasis, C-type lectin receptor signaling pathway, Cellular senescence, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, Epstein-Barr virus infection, FoxO signaling pathway, Graft-versus-host disease, HIF-1 signaling pathway, Hematopoietic cell lineage, Hepatitis B, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Intestinal immune network for IgA production, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Legionellosis, Lipid and atherosclerosis, Malaria, Measles, NOD-like receptor signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Rheumatoid arthritis, Salmonella infection, TNF signaling pathway, Th17 cell differentiation, Toll-like receptor signaling pathway, Transcriptional misregulation in cancer, Tuberculosis, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection 💬[2] 46, 96 💬
23 Olsalazine [1] Olsalazine[2] Olsalazine sodium ,
Olsalazine 💬 		--[1] 271 💬
24 OM85 [1] Broncho-vaxom---[1] 85 💬
25 Omadacycline [1] Omadacycline[2] Omadacycline ,
Omadacycline tosylate 💬 		--[1] 299 💬
26 Omalizumab [1] Omalizumab[1] Omalizumab 💬 [1] FCER1A 💬 [4] Asthma, Fc epsilon RI signaling pathway, Phospholipase D signaling pathway, Sphingolipid signaling pathway 💬[7] 46, 53, 65, 98, 162, 226, 299 💬
27 Omaveloxolone [1] Omaveloxolone[1] Omaveloxolone 💬 [1] NFE2L2 💬 [7] Chemical carcinogenesis - reactive oxygen species, Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Lipid and atherosclerosis, Parkinson disease, Pathways in cancer, Protein processing in endoplasmic reticulum 💬[1] 18 💬
28 Omega-3 fatty acids [5] Omega 3 fatty acids; Omega-3; Omega-3 fatty acid; Omega-3 fatty acids; Omega-3-acid triglycerides---[7] 13, 46, 49, 66, 79, 96, 299 💬
29 Omeprazole [3] Omeprazol; Omeprazole; Omeprazole magnesium[3] Omeprazole ,
Omeprazole sodium ,
Omeprazole magnesium 💬 		[2] ATP4A,
ATP4B 💬 		[3] Collecting duct acid secretion, Gastric acid secretion, Oxidative phosphorylation 💬[16] 6, 13, 21, 46, 51, 85, 90, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬
30 Omidubicel [1] Omidubicel[1] Omidubicel 💬 [1] CD34 💬 [2] Cell adhesion molecules, Hematopoietic cell lineage 💬[1] 60 💬
31 Omigapil [1] Omigapil---[1] 113 💬
32 OMS906 [0] ---[1] 62 💬
33 Onasemnogene abeparvovec [1] Onasemnogene abeparvovec[1] Onasemnogene abeparvovec 💬 --[1] 3 💬
34 Ondansetron [2] Ondansetron; Ondansetron hydrochloride dihydrate[2] Ondansetron ,
Ondansetron hydrochloride hydrate 💬 		[5] HTR3,
HTR3,
HTR3,
HTR3,
HTR3 💬 		[3] Neuroactive ligand signaling, Serotonergic synapse, Taste transduction 💬[5] 6, 97, 98, 107, 231 💬
35 Ontamalimab [1] Ontamalimab---[2] 96, 97 💬
36 Opicapone [1] Opicapone[1] Opicapone 💬 [1] COMT 💬 [3] Dopaminergic synapse, Steroid hormone biosynthesis, Tyrosine metabolism 💬[1] 6 💬
37 Opicinumab [1] Opicinumab[1] Opicinumab 💬 --[1] 13 💬
38 Oprelvekin [2] Interleukin-11; Recombinant interleukin-11[1] Oprelvekin 💬 [1] IL11RA 💬 [3] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway 💬[3] 96, 97, 288 💬
39 Orelabrutinib [1] Orelabrutinib[1] Orelabrutinib 💬 [1] BTK 💬 [7] B cell receptor signaling pathway, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, NF-kappa B signaling pathway, Osteoclast differentiation, Platelet activation, Primary immunodeficiency 💬[4] 13, 49, 61, 63 💬
40 Orilanolimab [1] Orilanolimab[1] Orilanolimab 💬 --[1] 61 💬
41 ORM-12741 [1] ORM-12741---[1] 51 💬
42 Ornithine [0] [2] Ornithine ,
Ornithine aspartate 💬 		--[2] 245, 251 💬
43 Orvepitant [1] Orvepitant[1] Orvepitant 💬 [1] TACR1 💬 [3] Calcium signaling pathway, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction 💬[1] 85 💬
44 Oseltamivir [1] Oseltamivir[2] Oseltamivir phosphate ,
Oseltamivir 💬 		--[2] 97, 299 💬
45 Osilodrostat [1] Osilodrostat[2] Osilodrostat ,
Osilodrostat phosphate 💬 		[1] CYP11B2 💬 [2] Aldosterone synthesis and secretion, Steroid hormone biosynthesis 💬[1] 75 💬
46 Otelixizumab [1] Otelixizumab[1] Otelixizumab 💬 [3] CD3D,
CD3E,
CD3G 💬 		[11] Chagas disease, Epstein-Barr virus infection, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, Human immunodeficiency virus 1 infection, Measles, PD-L1 expression and PD-1 checkpoint pathway in cancer, Primary immunodeficiency, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation 💬[1] 46 💬
47 Otilimab [1] Otilimab[1] Otilimab 💬 [1] CSF2 💬 [16] Acute myeloid leukemia, Amoebiasis, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Fc epsilon RI signaling pathway, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, IL-17 signaling pathway, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Natural killer cell mediated cytotoxicity, Rheumatoid arthritis, Shigellosis, T cell receptor signaling pathway, TNF signaling pathway, Transcriptional misregulation in cancer 💬[1] 46 💬
48 OTL-103 [1] OTL-103---[1] 65 💬
49 OTL-203 [1] OTL-203---[1] 19 💬
50 Oxabact [1] Oxalobacter formigenes---[1] 234 💬
51 Oxaloacetic acid [2] Oxaloacetate; Oxaloacetic acid---[3] 2, 6, 11 💬
52 Oxandrolone [1] Oxandrolone[1] Oxandrolone 💬 [1] AR 💬 [4] Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬[2] 211, 285 💬
53 Oxatomide [1] Oxatomide[1] Oxatomide 💬 [1] ALOX5 💬 [6] Arachidonic acid metabolism, Efferocytosis, Fc epsilon RI signaling pathway, Ovarian steroidogenesis, Serotonergic synapse, Toxoplasmosis 💬[1] 113 💬
54 Oxcarbazepine [1] Oxcarbazepine[1] Oxcarbazepine 💬 [5] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬 		[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬[1] 13 💬
55 Oxiconazole [1] Oxiconazole[2] Oxiconazole nitrate ,
Oxiconazole 💬 		--[1] 160 💬
56 Oxitriptan [1] Oxitriptan[1] Oxitriptan 💬 --[1] 97 💬
57 Oxybuprocaine [1] Oxybuprocaine[2] Benoxinate hydrochloride ,
Oxybuprocaine 💬 		[5] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬 		[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬[1] 6 💬
58 Oxybutynin [0] [2] Oxybutynin ,
Oxybutynin chloride 💬 		[5] CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5 💬 		[14] Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬[3] 6, 13, 53 💬
59 Oxycodone [2] Oxycodone; Oxycodone hydrochloride[3] Oxycodone hydrochloride ,
Oxycodone terephthalate ,
Oxycodone 💬 		[3] OPRD1,
OPRK1,
OPRM1 💬 		[7] Estrogen signaling pathway, Hormone signaling, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[6] 6, 46, 70, 226, 231, 298 💬
60 Oxygen [1] Oxygen[1] Oxygen 💬 --[18] 6, 19, 22, 49, 70, 85, 86, 88, 96, 97, 149, 168, 211, 235, 271, 298, 299, 330 💬
61 Oxymatrine [1] Oxymatrine---[1] 37 💬
62 Oxyquinoline [1] Oxine[2] Oxyquinoline sulfate ,
Oxyquinoline 💬 		--[2] 13, 51 💬
63 Oxytocin [1] Oxytocin[1] Oxytocin 💬 [1] OXTR 💬 [5] Calcium signaling pathway, Hormone signaling, Neuroactive ligand-receptor interaction, Oxytocin signaling pathway, cAMP signaling pathway 💬[8] 6, 70, 72, 127, 168, 193, 206, 226 💬
64 Ozanezumab [1] Ozanezumab[1] Ozanezumab 💬 [1] RTN4 💬 [1] Alzheimer disease 💬[1] 2 💬
65 Ozanimod [2] Ozanimod; Ozanimod hydrochloride[2] Ozanimod hydrochloride ,
Ozanimod 💬 		[5] S1PR1,
S1PR2,
S1PR3,
S1PR4,
S1PR5 💬 		[4] Efferocytosis, FoxO signaling pathway, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway 💬[3] 13, 96, 97 💬
66 Ozone [1] Ozone---[4] 49, 51, 70, 226 💬
67 Ozoralizumab [1] Ozoralizumab[1] Ozoralizumab 💬 [1] TNF 💬 [66] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[1] 46 💬