Drug Description in Trials / DrugBank / KEGG DRUG

  

Search results

No. DrugBank Drug (Description in trials) KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1 Ianalumab [1] Ianalumab[1] Ianalumab 💬 [1] TNFRSF13C 💬 [5] Cytokine-cytokine receptor interaction, Human T-cell leukemia virus 1 infection, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Primary immunodeficiency 💬[8] 35, 46, 49, 51, 53, 61, 63, 95 💬
2 Ibandronate [2] Ibandronate; Ibandronic acid[2] Ibandronate sodium ,
Ibandronic acid 💬 		[1] FDPS 💬 [3] Human T-cell leukemia virus 1 infection, Influenza A, Terpenoid backbone biosynthesis 💬[3] 46, 49, 274 💬
3 Ibrutinib [1] Ibrutinib[1] Ibrutinib 💬 [1] BTK 💬 [7] B cell receptor signaling pathway, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, NF-kappa B signaling pathway, Osteoclast differentiation, Platelet activation, Primary immunodeficiency 💬[3] 28, 60, 61 💬
4 Ibudilast [1] Ibudilast[1] Ibudilast 💬 [8] CYSLTR1,
PDE3A,
PDE3B,
PDE4,
PDE4,
PDE4,
PDE4,
PTGIR 💬 		[15] Apelin signaling pathway, Calcium signaling pathway, Glucagon signaling pathway, Insulin signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Parathyroid hormone synthesis, secretion and action, Platelet activation, Progesterone-mediated oocyte maturation, Purine metabolism, Regulation of lipolysis in adipocytes, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[2] 2, 13 💬
5 Ibuprofen [1] Ibuprofen[5] Ibuprofen ,
Ibuprofen aluminum ,
Ibuprofen lysine ,
Ibuprofen sodium ,
Ibuprofen sodium 💬 		[2] PTGS1,
PTGS2 💬 		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Efferocytosis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[6] 13, 46, 65, 113, 271, 299 💬
6 Icatibant [2] Icatibant; Icatibant acetate[1] Icatibant acetate 💬 [1] BDKRB2 💬 [10] Calcium signaling pathway, Chagas disease, Complement and coagulation cascades, Endocrine and other factor-regulated calcium reabsorption, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Pathways in cancer, Regulation of actin cytoskeleton, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[1] 65 💬
7 Icerguastat [1] Icerguastat---[1] 2 💬
8 Icosapent [1] Eicosapentaenoic acid[1] Icosapent 💬 --[9] 46, 48, 49, 96, 97, 113, 296, 297, 338 💬
9 Icosapent ethyl [1] Ethyl-EPA[1] Icosapent ethyl 💬 --[1] 8 💬
10 Icotinib [1] Icotinib[1] Icotinib 💬 [1] EGFR 💬 [47] Adherens junction, Bladder cancer, Breast cancer, Calcium signaling pathway, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Coronavirus disease - COVID-19, Cushing syndrome, Endocytosis, Endometrial cancer, Epithelial cell signaling in Helicobacter pylori infection, ErbB signaling pathway, Estrogen signaling pathway, Focal adhesion, FoxO signaling pathway, Gap junction, Gastric cancer, Glioma, GnRH signaling pathway, HIF-1 signaling pathway, Hepatitis C, Hepatocellular carcinoma, Human cytomegalovirus infection, Human papillomavirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanoma, MicroRNAs in cancer, Non-small cell lung cancer, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis, Virion - Hepatitis viruses 💬[1] 34 💬
11 ICX-RHY [0] ---[1] 36 💬
12 Idebenone [1] Idebenone[1] Idebenone 💬 --[7] 6, 8, 13, 18, 21, 113, 302 💬
13 Idecabtagene vicleucel [1] Idecabtagene vicleucel[1] Idecabtagene vicleucel 💬 [1] TNFRSF17 💬 [2] Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production 💬[1] 28 💬
14 Idursulfase [2] Idursulfasa; Idursulfase[1] Idursulfase 💬 [1] IDS 💬 [2] Glycosaminoglycan degradation, Lysosome 💬[1] 19 💬
15 Idursulfase beta [2] Hunterase; Idursulfase beta[1] Idursulfase beta 💬 [1] IDS 💬 [2] Glycosaminoglycan degradation, Lysosome 💬[1] 19 💬
16 Ifenprodil [1] Ifenprodil[2] Ifenprodil tartrate ,
Ifenprodil 💬 		[3] ADRA1A,
ADRA1B,
ADRA1D 💬 		[9] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 13 💬
17 Ifetroban [2] Ifetroban; Ifetroban sodium[2] Ifetroban ,
Ifetroban sodium 💬 		[1] TBXA2R 💬 [3] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Platelet activation 💬[2] 85, 113 💬
18 Ifosfamide [1] Ifosfamide[1] Ifosfamide 💬 --[1] 34 💬
19 Iguratimod [1] Iguratimod[1] Iguratimod 💬 [1] NFKB1 💬 [75] AGE-RAGE signaling pathway in diabetic complications, Acute myeloid leukemia, Adipocytokine signaling pathway, Alcoholic liver disease, Alzheimer disease, Amoebiasis, Apoptosis, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Cellular senescence, Chagas disease, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Chronic myeloid leukemia, Cocaine addiction, Coronavirus disease - COVID-19, Cytosolic DNA-sensing pathway, Diabetic cardiomyopathy, Epithelial cell signaling in Helicobacter pylori infection, Epstein-Barr virus infection, Fluid shear stress and atherosclerosis, HIF-1 signaling pathway, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Kaposi sarcoma-associated herpesvirus infection, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, Longevity regulating pathway, MAPK signaling pathway, Measles, MicroRNAs in cancer, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Neurotrophin signaling pathway, Neutrophil extracellular trap formation, Non-alcoholic fatty liver disease, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathogenic Escherichia coli infection, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Pertussis, Prolactin signaling pathway, Prostate cancer, RIG-I-like receptor signaling pathway, Ras signaling pathway, Relaxin signaling pathway, Salmonella infection, Shigellosis, Small cell lung cancer, Sphingolipid signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Transcriptional misregulation in cancer, Tuberculosis, Viral carcinogenesis, Yersinia infection, cAMP signaling pathway 💬[6] 46, 49, 51, 53, 271, 300 💬
20 IKT-001Pro [1] IKT-001PRO---[1] 86 💬
21 Iloperidone [1] Iloperidone[1] Iloperidone 💬 [4] DRD2,
HTR2,
HTR2,
HTR2 💬 		[13] Alcoholism, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Inflammatory mediator regulation of TRP channels, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Serotonergic synapse, cAMP signaling pathway 💬[1] 6 💬
22 Iloprost [1] Iloprost[2] Iloprost ,
Iloprost tromethamine 💬 		[1] PTGIR 💬 [3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[4] 51, 84, 85, 86 💬
23 Imatinib [2] Imatinib; Imatinib mesylate[2] Imatinib mesylate ,
Imatinib 💬 		[3] ABL1,
KIT,
PDGFRA 💬 		[31] Acute myeloid leukemia, Axon guidance, Breast cancer, Calcium signaling pathway, Cell cycle, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Choline metabolism in cancer, Chronic myeloid leukemia, Endocytosis, ErbB signaling pathway, Focal adhesion, Gap junction, Glioma, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanogenesis, Melanoma, MicroRNAs in cancer, Neurotrophin signaling pathway, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Viral myocarditis 💬[12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
24 IMCY-0141 [1] IMCY-0141---[1] 13 💬
25 Imidacloprid [0] ---[5] 19, 20, 125, 234, 326 💬
26 Imidapril [1] Imidapril[2] Imidapril hydrochloride ,
Imidapril 💬 		[1] ACE 💬 [6] Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬[1] 67 💬
27 Imiglucerase [2] Imiglucerasa; Imiglucerase[2] Alglucerase ,
Imiglucerase 💬 		[1] GBA 💬 [4] Cornified envelope formation, Lysosome, Other glycan degradation, Sphingolipid metabolism 💬[1] 19 💬
28 Imipenem [0] [2] Imipenem ,
Imipenem 💬 		--[2] 60, 299 💬
29 Imiquimod [0] [1] Imiquimod 💬 [1] TLR7 💬 [5] Coronavirus disease - COVID-19, Influenza A, Measles, Neutrophil extracellular trap formation, Toll-like receptor signaling pathway 💬[2] 34, 51 💬
30 Imlifidase [3] HMED-ides; Ides; Imlifidase[1] Imlifidase 💬 --[5] 43, 44, 64, 113, 221 💬
31 Implitapide [1] Implitapide---[1] 79 💬
32 Imsidolimab [1] Imsidolimab[1] Imsidolimab 💬 [1] IL1RL2 💬 [1] Cytokine-cytokine receptor interaction 💬[1] 37 💬
33 Imvotamab [1] Imvotamab[1] Imvotamab 💬 [2] CD3E,
MS4A1 💬 		[11] Chagas disease, Epstein-Barr virus infection, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, Human immunodeficiency virus 1 infection, Measles, PD-L1 expression and PD-1 checkpoint pathway in cancer, Primary immunodeficiency, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation 💬[2] 46, 49 💬
34 Inaticabtagene Autoleucel [0] ---[1] 49 💬
35 INBRX-101 [0] ---[1] 231 💬
36 Inclisiran [3] ALN-pcssc; Inclisiran; Inclisiran sodium[2] Inclisiran ,
Inclisiran sodium 💬 		[1] PCSK9 💬 [1] Cholesterol metabolism 💬[1] 79 💬
37 Indapamide [0] [1] Indapamide 💬 [1] SLC12A3 💬 [1] Parathyroid hormone synthesis, secretion and action 💬[1] 13 💬
38 Indian frankincense [0] ---[1] 13 💬
39 Indigo [1] Indigo---[3] 97, 289, 300 💬
40 Indinavir [1] Indinavir[3] Indinavir sulfate ,
Indinavir sulfate ethanolate ,
Indinavir 💬 		--[1] 265 💬
41 Indium [0] ---[3] 28, 84, 299 💬
42 Indocyanine green [1] Indocyanine green[1] Indocyanine green 💬 --[8] 22, 46, 51, 96, 235, 278, 291, 296 💬
43 Indomethacin [2] Indometacin; Indomethacin[2] Indomethacin ,
Indomethacin sodium 💬 		[2] PTGS1,
PTGS2 💬 		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Efferocytosis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[3] 225, 271, 298 💬
44 Indopan [0] ---[5] 2, 8, 19, 46, 97 💬
45 Inebilizumab [1] Inebilizumab[1] Inebilizumab 💬 [1] CD19 💬 [5] B cell receptor signaling pathway, Epstein-Barr virus infection, Hematopoietic cell lineage, PI3K-Akt signaling pathway, Primary immunodeficiency 💬[6] 11, 13, 46, 49, 51, 300 💬
46 Infigratinib [2] Infigratinib; Infigratinib phosphate[2] Infigratinib ,
Infigratinib phosphate 💬 		[3] FGFR1,
FGFR2,
FGFR3 💬 		[20] Adherens junction, Bladder cancer, Breast cancer, Calcium signaling pathway, Central carbon metabolism in cancer, Endocytosis, Gastric cancer, MAPK signaling pathway, Melanoma, MicroRNAs in cancer, PI3K-Akt signaling pathway, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Signaling pathways regulating pluripotency of stem cells, Thermogenesis 💬[1] 276 💬
47 Infliximab [1] Infliximab[1] Infliximab 💬 [1] TNF 💬 [66] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 95, 96, 97, 98, 107, 164, 269, 270, 271 💬
48 Inosine [1] Inosine[1] Inosine 💬 --[5] 2, 6, 13, 85, 122 💬
49 Inositol [1] Inositol[1] Inositol 💬 --[2] 96, 97 💬
50 Inotersen [1] Inotersen[2] Inotersen ,
Inotersen sodium 💬 		[1] TTR 💬 [1] Thyroid hormone synthesis 💬[1] 28 💬
51 INS018_055 [1] INS018_055---[1] 85 💬
52 Insulin detemir [0] [1] Insulin detemir 💬 [1] INSR 💬 [23] AMPK signaling pathway, Adherens junction, Aldosterone-regulated sodium reabsorption, Alzheimer disease, Diabetic cardiomyopathy, FoxO signaling pathway, HIF-1 signaling pathway, Hormone signaling, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, MAPK signaling pathway, Non-alcoholic fatty liver disease, Ovarian steroidogenesis, PI3K-Akt signaling pathway, Phospholipase D signaling pathway, Rap1 signaling pathway, Ras signaling pathway, Regulation of lipolysis in adipocytes, Type II diabetes mellitus, cGMP-PKG signaling pathway, mTOR signaling pathway 💬[1] 299 💬
53 Insulin glargine [1] Insulin glargine[1] Insulin glargine 💬 [1] INSR 💬 [23] AMPK signaling pathway, Adherens junction, Aldosterone-regulated sodium reabsorption, Alzheimer disease, Diabetic cardiomyopathy, FoxO signaling pathway, HIF-1 signaling pathway, Hormone signaling, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, MAPK signaling pathway, Non-alcoholic fatty liver disease, Ovarian steroidogenesis, PI3K-Akt signaling pathway, Phospholipase D signaling pathway, Rap1 signaling pathway, Ras signaling pathway, Regulation of lipolysis in adipocytes, Type II diabetes mellitus, cGMP-PKG signaling pathway, mTOR signaling pathway 💬[1] 299 💬
54 Insulin human [1] Human insulin[1] Insulin human 💬 [1] INSR 💬 [23] AMPK signaling pathway, Adherens junction, Aldosterone-regulated sodium reabsorption, Alzheimer disease, Diabetic cardiomyopathy, FoxO signaling pathway, HIF-1 signaling pathway, Hormone signaling, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, MAPK signaling pathway, Non-alcoholic fatty liver disease, Ovarian steroidogenesis, PI3K-Akt signaling pathway, Phospholipase D signaling pathway, Rap1 signaling pathway, Ras signaling pathway, Regulation of lipolysis in adipocytes, Type II diabetes mellitus, cGMP-PKG signaling pathway, mTOR signaling pathway 💬[1] 156 💬
55 Insulin lispro [1] Insulin lispro[1] Insulin lispro 💬 [1] INSR 💬 [23] AMPK signaling pathway, Adherens junction, Aldosterone-regulated sodium reabsorption, Alzheimer disease, Diabetic cardiomyopathy, FoxO signaling pathway, HIF-1 signaling pathway, Hormone signaling, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, MAPK signaling pathway, Non-alcoholic fatty liver disease, Ovarian steroidogenesis, PI3K-Akt signaling pathway, Phospholipase D signaling pathway, Rap1 signaling pathway, Ras signaling pathway, Regulation of lipolysis in adipocytes, Type II diabetes mellitus, cGMP-PKG signaling pathway, mTOR signaling pathway 💬[1] 53 💬
56 Interferon alfa [0] [1] Interferon alfa 💬 [2] IFNAR1,
IFNAR2 💬 		[18] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Measles, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Osteoclast differentiation, PI3K-Akt signaling pathway, Pathways in cancer, Toll-like receptor signaling pathway 💬[2] 25, 56 💬
57 Interferon alfa-2a [2] Interferon ALFA-2A; Interferon alpha-2A[1] Interferon alfa-2a 💬 [2] IFNAR1,
IFNAR2 💬 		[18] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Measles, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Osteoclast differentiation, PI3K-Akt signaling pathway, Pathways in cancer, Toll-like receptor signaling pathway 💬[1] 56 💬
58 Interferon alfa-2b [1] Interferon ALFA-2B[1] Interferon alfa-2b 💬 [2] IFNAR1,
IFNAR2 💬 		[18] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Measles, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Osteoclast differentiation, PI3K-Akt signaling pathway, Pathways in cancer, Toll-like receptor signaling pathway 💬[1] 25 💬
59 Interferon beta-1a [4] Interferon beta 1-A; Interferon beta 1A; Interferon BETA-1A; Interferon-BETA-1A[1] Interferon beta-1a 💬 [2] IFNAR1,
IFNAR2 💬 		[18] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Measles, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Osteoclast differentiation, PI3K-Akt signaling pathway, Pathways in cancer, Toll-like receptor signaling pathway 💬[3] 13, 96, 97 💬
60 Interferon beta-1b [3] Interferon beta 1B; Interferon BETA-1B; Interferon-BETA-1B[1] Interferon beta-1b 💬 [2] IFNAR1,
IFNAR2 💬 		[18] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Measles, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Osteoclast differentiation, PI3K-Akt signaling pathway, Pathways in cancer, Toll-like receptor signaling pathway 💬[1] 13 💬
61 Interferon Gamma [1] Interferon gamma---[8] 18, 65, 85, 96, 228, 299, 301, 326 💬
62 Interferon gamma-1b [1] Interferon gamma-1B[1] Interferon gamma-1b 💬 [2] IFNGR1,
IFNGR2 💬 		[18] Chagas disease, Cytokine-cytokine receptor interaction, HIF-1 signaling pathway, Herpes simplex virus 1 infection, Inflammatory bowel disease, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Natural killer cell mediated cytotoxicity, Necroptosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways in cancer, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis 💬[7] 18, 65, 85, 228, 299, 301, 326 💬
63 Inulin [1] Inulin[1] Inulin 💬 --[3] 6, 97, 299 💬
64 INZ-701 [1] INZ-701---[1] 166 💬
65 Iodide I-123 [1] I-123---[2] 2, 6 💬
66 Iodine [1] Iodine[1] Iodine 💬 --[3] 28, 46, 96 💬
67 Ioflupane I-123 [2] Ioflupane; Ioflupane I 123[1] Ioflupane I 123 💬 [1] SLC6A3 💬 [8] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Neuroactive ligand signaling, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Synaptic vesicle cycle 💬[1] 6 💬
68 Iohexol [1] Iohexol[1] Iohexol 💬 --[2] 19, 67 💬
69 ION283 [1] ION283---[1] 309 💬
70 ION356 [1] ION356---[1] 139 💬
71 ION582 [1] ION582---[1] 201 💬
72 Ipilimumab [1] Ipilimumab[1] Ipilimumab 💬 [1] CTLA4 💬 [4] Autoimmune thyroid disease, Cell adhesion molecules, Rheumatoid arthritis, T cell receptor signaling pathway 💬[1] 159 💬
73 Ipratropium [1] Ipratropium---[1] 6 💬
74 Iproniazid [1] Iproniazid[2] Iproniazid ,
Iproniazid phosphate 💬 		[2] MAO,
MAO 💬 		[13] Alcoholism, Amphetamine addiction, Arginine and proline metabolism, Cocaine addiction, Dopaminergic synapse, Drug metabolism - cytochrome P450, Glycine, serine and threonine metabolism, Histidine metabolism, Parkinson disease, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬[1] 6 💬
75 Iptacopan [1] Iptacopan[2] Iptacopan ,
Iptacopan hydrochloride 💬 		[1] CFB 💬 [3] Complement and coagulation cascades, Coronavirus disease - COVID-19, Staphylococcus aureus infection 💬[6] 11, 61, 62, 66, 109, 222 💬
76 Irbesartan [1] Irbesartan[1] Irbesartan 💬 [1] AGTR1 💬 [17] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Hormone signaling, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[4] 66, 167, 168, 222 💬
77 Iron [1] Iron[1] Ferrous fumarate 💬 --[6] 18, 60, 96, 97, 238, 284 💬
78 Iron Dextran [1] Iron dextran[1] Iron dextran 💬 --[2] 62, 97 💬
79 Iron isomaltoside 1000 [2] Iron isomaltoside 1000; Monofer---[1] 97 💬
80 Iron sucrose [1] Iron sucrose[1] Iron sucrose 💬 --[3] 62, 96, 97 💬
81 Isaralgagene civaparvovec [1] Isaralgagene civaparvovec---[1] 19 💬
82 Isatuximab [1] Isatuximab[1] Isatuximab 💬 [1] CD38 💬 [6] Calcium signaling pathway, Hematopoietic cell lineage, Nicotinate and nicotinamide metabolism, Oxytocin signaling pathway, Pancreatic secretion, Salivary secretion 💬[3] 28, 61, 283 💬
83 Iscalimab [1] Iscalimab[1] Iscalimab 💬 [1] TNFRSF5 💬 [17] Allograft rejection, Asthma, Autoimmune thyroid disease, Cell adhesion molecules, Cytokine-cytokine receptor interaction, Epstein-Barr virus infection, Human T-cell leukemia virus 1 infection, Intestinal immune network for IgA production, Lipid and atherosclerosis, Malaria, NF-kappa B signaling pathway, Primary immunodeficiency, Systemic lupus erythematosus, Toll-like receptor signaling pathway, Toxoplasmosis, Transcriptional misregulation in cancer, Viral myocarditis 💬[2] 49, 53 💬
84 ISIS 104838 [1] Isis 104838---[1] 46 💬
85 Isoflurane [1] Isoflurane[1] Isoflurane 💬 --[1] 6 💬
86 Isoleucine [1] Isoleucine[1] Isoleucine 💬 --[1] 244 💬
87 Isoniazid [1] Isoniazid[1] Isoniazid 💬 --[3] 49, 65, 254 💬
88 Isosorbide [0] [1] Isosorbide 💬 --[1] 113 💬
89 Isosorbide dinitrate [0] [1] Isosorbide dinitrate 💬 --[1] 113 💬
90 Isotretinoin [1] Isotretinoin[1] Isotretinoin 💬 [2] RARA,
RARB 💬 		[8] Acute myeloid leukemia, Estrogen signaling pathway, Gastric cancer, Non-small cell lung cancer, Pathways in cancer, Small cell lung cancer, Th17 cell differentiation, Transcriptional misregulation in cancer 💬[4] 36, 39, 159, 160 💬
91 Isoxaflutole [0] ---[5] 6, 13, 18, 121, 299 💬
92 Isoxsuprine [1] Isoxsuprine hydrochloride[2] Isoxsuprine hydrochloride ,
Isoxsuprine 💬 		[1] ADRB2 💬 [11] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 13 💬
93 Isradipine [1] Isradipine[1] Isradipine 💬 [4] CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S 💬 		[37] Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 6 💬
94 Istradefylline [1] Istradefylline[1] Istradefylline 💬 [1] ADORA2A 💬 [8] Alcoholism, Calcium signaling pathway, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Vascular smooth muscle contraction, cAMP signaling pathway 💬[1] 6 💬
95 Itacitinib [2] Itacitinib; Itacitinib adipate[2] Itacitinib ,
Itacitinib adipate 💬 		[1] JAK1 💬 [27] Coronavirus disease - COVID-19, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Measles, NOD-like receptor signaling pathway, Necroptosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬[4] 46, 51, 97, 228 💬
96 Itepekimab [1] Itepekimab[1] Itepekimab 💬 [1] IL33 💬 [4] Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, Influenza A, Necroptosis 💬[1] 299 💬
97 ITI-214 [1] ITI-214---[1] 6 💬
98 Itolizumab [1] Itolizumab[1] Itolizumab 💬 [1] CD6 💬 [1] Cell adhesion molecules 💬[2] 49, 50 💬
99 Itraconazole [1] Itraconazole[1] Itraconazole 💬 --[8] 2, 3, 46, 65, 96, 97, 227, 299 💬
100 Ivacaftor [1] Ivacaftor[1] Ivacaftor 💬 [1] CFTR 💬 [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[2] 299, 340 💬
101 Ixazomib [2] Ixazomib; Ixazomib citrate[2] Ixazomib ,
Ixazomib citrate 💬 		[1] PSMB5 💬 [8] Alzheimer disease, Amyotrophic lateral sclerosis, Huntington disease, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Prion disease, Proteasome, Spinocerebellar ataxia 💬[4] 13, 16, 28, 51 💬
102 Ixekizumab [1] Ixekizumab[1] Ixekizumab 💬 [1] IL17A 💬 [6] Alcoholic liver disease, Cytokine-cytokine receptor interaction, IL-17 signaling pathway, Inflammatory bowel disease, Rheumatoid arthritis, Th17 cell differentiation 💬[8] 36, 37, 46, 107, 160, 162, 269, 271 💬