Target Gene/Pathway Pathway / Gene

  

Search results

No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank Disease ID
1 ATP1A 💬 [19] cGMP-PKG signaling pathway, cAMP signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Cytoskeleton in muscle cells, Insulin secretion, Thyroid hormone synthesis, Thyroid hormone signaling pathway, Aldosterone synthesis and secretion, Aldosterone-regulated sodium reabsorption, Endocrine and other factor-regulated calcium reabsorption, Proximal tubule bicarbonate reclamation, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Carbohydrate digestion and absorption, Protein digestion and absorption, Bile secretion, Mineral absorption Digitoxin 💬 Digitoxin [1] 299 💬
2 ATP1A 💬 [19] cGMP-PKG signaling pathway, cAMP signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Cytoskeleton in muscle cells, Insulin secretion, Thyroid hormone synthesis, Thyroid hormone signaling pathway, Aldosterone synthesis and secretion, Aldosterone-regulated sodium reabsorption, Endocrine and other factor-regulated calcium reabsorption, Proximal tubule bicarbonate reclamation, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Carbohydrate digestion and absorption, Protein digestion and absorption, Bile secretion, Mineral absorption Digitoxin 💬 Digitoxin [1] 299 💬
3 ATP1A 💬 [19] cGMP-PKG signaling pathway, cAMP signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Cytoskeleton in muscle cells, Insulin secretion, Thyroid hormone synthesis, Thyroid hormone signaling pathway, Aldosterone synthesis and secretion, Aldosterone-regulated sodium reabsorption, Endocrine and other factor-regulated calcium reabsorption, Proximal tubule bicarbonate reclamation, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Carbohydrate digestion and absorption, Protein digestion and absorption, Bile secretion, Mineral absorption Digitoxin 💬 Digitoxin [1] 299 💬
4 ATP1A 💬 [19] cGMP-PKG signaling pathway, cAMP signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Cytoskeleton in muscle cells, Insulin secretion, Thyroid hormone synthesis, Thyroid hormone signaling pathway, Aldosterone synthesis and secretion, Aldosterone-regulated sodium reabsorption, Endocrine and other factor-regulated calcium reabsorption, Proximal tubule bicarbonate reclamation, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Carbohydrate digestion and absorption, Protein digestion and absorption, Bile secretion, Mineral absorption Digoxin 💬 Digoxin [3] 8, 46, 210 💬
5 ATP1A 💬 [19] cGMP-PKG signaling pathway, cAMP signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Cytoskeleton in muscle cells, Insulin secretion, Thyroid hormone synthesis, Thyroid hormone signaling pathway, Aldosterone synthesis and secretion, Aldosterone-regulated sodium reabsorption, Endocrine and other factor-regulated calcium reabsorption, Proximal tubule bicarbonate reclamation, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Carbohydrate digestion and absorption, Protein digestion and absorption, Bile secretion, Mineral absorption Digoxin 💬 Digoxin [3] 8, 46, 210 💬
6 ATP1A 💬 [19] cGMP-PKG signaling pathway, cAMP signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Cytoskeleton in muscle cells, Insulin secretion, Thyroid hormone synthesis, Thyroid hormone signaling pathway, Aldosterone synthesis and secretion, Aldosterone-regulated sodium reabsorption, Endocrine and other factor-regulated calcium reabsorption, Proximal tubule bicarbonate reclamation, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Carbohydrate digestion and absorption, Protein digestion and absorption, Bile secretion, Mineral absorption Digoxin 💬 Digoxin [3] 8, 46, 210 💬
7 ATP1A 💬 [19] cGMP-PKG signaling pathway, cAMP signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Cytoskeleton in muscle cells, Insulin secretion, Thyroid hormone synthesis, Thyroid hormone signaling pathway, Aldosterone synthesis and secretion, Aldosterone-regulated sodium reabsorption, Endocrine and other factor-regulated calcium reabsorption, Proximal tubule bicarbonate reclamation, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Carbohydrate digestion and absorption, Protein digestion and absorption, Bile secretion, Mineral absorption Digitoxin 💬 Digitoxin [1] 299 💬
8 ATP1A 💬 [19] cGMP-PKG signaling pathway, cAMP signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Cytoskeleton in muscle cells, Insulin secretion, Thyroid hormone synthesis, Thyroid hormone signaling pathway, Aldosterone synthesis and secretion, Aldosterone-regulated sodium reabsorption, Endocrine and other factor-regulated calcium reabsorption, Proximal tubule bicarbonate reclamation, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Carbohydrate digestion and absorption, Protein digestion and absorption, Bile secretion, Mineral absorption Digoxin 💬 Digoxin [3] 8, 46, 210 💬
9 DMD 💬 [5] Cytoskeleton in muscle cells, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy, Viral myocarditis Delandistrogene moxeparvovec 💬 Delandistrogene moxeparvovec [1] 113 💬
10 DMD 💬 [5] Cytoskeleton in muscle cells, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy, Viral myocarditis Viltolarsen 💬 Viltolarsen [1] 113 💬
11 DMD 💬 [5] Cytoskeleton in muscle cells, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy, Viral myocarditis Drisapersen 💬 Drisapersen [1] 113 💬
12 DMD 💬 [5] Cytoskeleton in muscle cells, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy, Viral myocarditis Casimersen 💬 Casimersen [1] 113 💬
13 DMD 💬 [5] Cytoskeleton in muscle cells, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy, Viral myocarditis Eteplirsen 💬 Eteplirsen [1] 113 💬
14 DMD 💬 [5] Cytoskeleton in muscle cells, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy, Viral myocarditis Golodirsen 💬 Golodirsen [1] 113 💬
15 ITGA4 💬 [15] PI3K-Akt signaling pathway, Focal adhesion, ECM-receptor interaction, Cell adhesion molecules, Hematopoietic cell lineage, Leukocyte transendothelial migration, Intestinal immune network for IgA production, Regulation of actin cytoskeleton, Cytoskeleton in muscle cells, Yersinia infection, Leishmaniasis, Human papillomavirus infection, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Firategrast 💬 Firategrast [1] 13 💬
16 ITGA4 💬 [15] PI3K-Akt signaling pathway, Focal adhesion, ECM-receptor interaction, Cell adhesion molecules, Hematopoietic cell lineage, Leukocyte transendothelial migration, Intestinal immune network for IgA production, Regulation of actin cytoskeleton, Cytoskeleton in muscle cells, Yersinia infection, Leishmaniasis, Human papillomavirus infection, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Natalizumab 💬 Natalizumab [5] 13, 15, 25, 46, 96 💬
17 ITGA4 💬 [15] PI3K-Akt signaling pathway, Focal adhesion, ECM-receptor interaction, Cell adhesion molecules, Hematopoietic cell lineage, Leukocyte transendothelial migration, Intestinal immune network for IgA production, Regulation of actin cytoskeleton, Cytoskeleton in muscle cells, Yersinia infection, Leishmaniasis, Human papillomavirus infection, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Vedolizumab 💬 Vedolizumab [3] 94, 96, 97 💬
18 ITGA4 💬 [15] PI3K-Akt signaling pathway, Focal adhesion, ECM-receptor interaction, Cell adhesion molecules, Hematopoietic cell lineage, Leukocyte transendothelial migration, Intestinal immune network for IgA production, Regulation of actin cytoskeleton, Cytoskeleton in muscle cells, Yersinia infection, Leishmaniasis, Human papillomavirus infection, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Abrilumab 💬 Abrilumab [2] 96, 97 💬
19 ITGA4 💬 [15] PI3K-Akt signaling pathway, Focal adhesion, ECM-receptor interaction, Cell adhesion molecules, Hematopoietic cell lineage, Leukocyte transendothelial migration, Intestinal immune network for IgA production, Regulation of actin cytoskeleton, Cytoskeleton in muscle cells, Yersinia infection, Leishmaniasis, Human papillomavirus infection, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Carotegrast methyl 💬 Carotegrast methyl [1] 97 💬
20 ITGA5 💬 [19] Virion - Herpesvirus, Phagosome, PI3K-Akt signaling pathway, Focal adhesion, ECM-receptor interaction, Hematopoietic cell lineage, Regulation of actin cytoskeleton, Cytoskeleton in muscle cells, Bacterial invasion of epithelial cells, Shigellosis, Pertussis, Yersinia infection, Human papillomavirus infection, Herpes simplex virus 1 infection, Proteoglycans in cancer, MicroRNAs in cancer, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Bexotegrast 💬 Bexotegrast [1] 94 💬
21 ITGB1 💬 [27] Virion - Rotavirus, Rap1 signaling pathway, Phagosome, PI3K-Akt signaling pathway, Axon guidance, Focal adhesion, ECM-receptor interaction, Cell adhesion molecules, Tight junction, Platelet activation, Leukocyte transendothelial migration, Regulation of actin cytoskeleton, Cytoskeleton in muscle cells, Bacterial invasion of epithelial cells, Pathogenic Escherichia coli infection, Shigellosis, Pertussis, Yersinia infection, Leishmaniasis, Toxoplasmosis, Human papillomavirus infection, Pathways in cancer, Proteoglycans in cancer, Small cell lung cancer, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Bexotegrast 💬 Bexotegrast [1] 94 💬
22 ITGB1 💬 [27] Virion - Rotavirus, Rap1 signaling pathway, Phagosome, PI3K-Akt signaling pathway, Axon guidance, Focal adhesion, ECM-receptor interaction, Cell adhesion molecules, Tight junction, Platelet activation, Leukocyte transendothelial migration, Regulation of actin cytoskeleton, Cytoskeleton in muscle cells, Bacterial invasion of epithelial cells, Pathogenic Escherichia coli infection, Shigellosis, Pertussis, Yersinia infection, Leishmaniasis, Toxoplasmosis, Human papillomavirus infection, Pathways in cancer, Proteoglycans in cancer, Small cell lung cancer, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Carotegrast methyl 💬 Carotegrast methyl [1] 97 💬
23 ITGB6 💬 [9] PI3K-Akt signaling pathway, Focal adhesion, ECM-receptor interaction, Regulation of actin cytoskeleton, Cytoskeleton in muscle cells, Human papillomavirus infection, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Bexotegrast 💬 Bexotegrast [1] 94 💬
24 ITGB7 💬 [12] PI3K-Akt signaling pathway, Focal adhesion, ECM-receptor interaction, Cell adhesion molecules, Intestinal immune network for IgA production, Regulation of actin cytoskeleton, Cytoskeleton in muscle cells, Human papillomavirus infection, Transcriptional misregulation in cancer, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Abrilumab 💬 Abrilumab [2] 96, 97 💬
25 ITGB7 💬 [12] PI3K-Akt signaling pathway, Focal adhesion, ECM-receptor interaction, Cell adhesion molecules, Intestinal immune network for IgA production, Regulation of actin cytoskeleton, Cytoskeleton in muscle cells, Human papillomavirus infection, Transcriptional misregulation in cancer, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Carotegrast methyl 💬 Carotegrast methyl [1] 97 💬
26 ITGB7 💬 [12] PI3K-Akt signaling pathway, Focal adhesion, ECM-receptor interaction, Cell adhesion molecules, Intestinal immune network for IgA production, Regulation of actin cytoskeleton, Cytoskeleton in muscle cells, Human papillomavirus infection, Transcriptional misregulation in cancer, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Etrolizumab 💬 Etrolizumab [2] 96, 97 💬
27 ITGB7 💬 [12] PI3K-Akt signaling pathway, Focal adhesion, ECM-receptor interaction, Cell adhesion molecules, Intestinal immune network for IgA production, Regulation of actin cytoskeleton, Cytoskeleton in muscle cells, Human papillomavirus infection, Transcriptional misregulation in cancer, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Vedolizumab 💬 Vedolizumab [3] 94, 96, 97 💬
28 MYH1s 💬 [2] Motor proteins, Cytoskeleton in muscle cells Sevasemten 💬 Sevasemten [1] 113 💬
29 MYH1s 💬 [2] Motor proteins, Cytoskeleton in muscle cells Sevasemten 💬 Sevasemten [1] 113 💬
30 MYH1s 💬 [2] Motor proteins, Cytoskeleton in muscle cells Sevasemten 💬 Sevasemten [1] 113 💬
31 MYH1s 💬 [2] Motor proteins, Cytoskeleton in muscle cells Sevasemten 💬 Sevasemten [1] 113 💬
32 MYH1s 💬 [2] Motor proteins, Cytoskeleton in muscle cells Sevasemten 💬 Sevasemten [1] 113 💬
33 MYH1s 💬 [2] Motor proteins, Cytoskeleton in muscle cells Sevasemten 💬 Sevasemten [1] 113 💬
34 MYH1s 💬 [2] Motor proteins, Cytoskeleton in muscle cells Sevasemten 💬 Sevasemten [1] 113 💬
35 MYH1s 💬 [2] Motor proteins, Cytoskeleton in muscle cells Sevasemten 💬 Sevasemten [1] 113 💬
36 MYH6_7 💬 [9] cGMP-PKG signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Motor proteins, Cytoskeleton in muscle cells, Thyroid hormone signaling pathway, Hypertrophic cardiomyopathy, Dilated cardiomyopathy, Viral myocarditis Aficamten 💬 Aficamten [1] 58 💬
37 MYH6_7 💬 [9] cGMP-PKG signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Motor proteins, Cytoskeleton in muscle cells, Thyroid hormone signaling pathway, Hypertrophic cardiomyopathy, Dilated cardiomyopathy, Viral myocarditis Aficamten 💬 Aficamten [1] 58 💬
38 MYH6_7 💬 [9] cGMP-PKG signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Motor proteins, Cytoskeleton in muscle cells, Thyroid hormone signaling pathway, Hypertrophic cardiomyopathy, Dilated cardiomyopathy, Viral myocarditis Mavacamten 💬 Mavacamten [1] 58 💬
39 MYL2 💬 [14] Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Apelin signaling pathway, Focal adhesion, Adherens junction, Tight junction, Leukocyte transendothelial migration, Regulation of actin cytoskeleton, Motor proteins, Cytoskeleton in muscle cells, Shigellosis, Salmonella infection, Hypertrophic cardiomyopathy, Dilated cardiomyopathy Aficamten 💬 Aficamten [1] 58 💬
40 MYL3 💬 [7] Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Apelin signaling pathway, Motor proteins, Cytoskeleton in muscle cells, Hypertrophic cardiomyopathy, Dilated cardiomyopathy Aficamten 💬 Aficamten [1] 58 💬
41 MYL4 💬 [5] Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Apelin signaling pathway, Motor proteins, Cytoskeleton in muscle cells Aficamten 💬 Aficamten [1] 58 💬
42 TNNC2 💬 [3] Calcium signaling pathway, Motor proteins, Cytoskeleton in muscle cells Reldesemtiv 💬 Reldesemtiv [2] 2, 3 💬
43 TNNI2 💬 [2] Motor proteins, Cytoskeleton in muscle cells Reldesemtiv 💬 Reldesemtiv [2] 2, 3 💬
44 TNNT3 💬 [2] Motor proteins, Cytoskeleton in muscle cells Reldesemtiv 💬 Reldesemtiv [2] 2, 3 💬