Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank 薬物名（臨床試験情報から抽出） KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
1 Alemtuzumab 1件: Alemtuzumab1件: Alemtuzumab 💬 --20件: 13, 15, 19, 20, 36, 43, 44, 46, 51, 60, 63, 65, 85, 96, 107, 164, 283, 284, 285, 326 💬
2 Amifostine 2件: Amifostine; Amifostine trihydrate1件: Amifostine 💬 --2件: 28, 63 💬
3 Aminophylline 1件: Aminophylline2件: Aminophylline ,
Aminophylline dihydrate 💬 		18件: ADORA1,
ADORA2B,
PDE1,
PDE1,
PDE1,
PDE10,
PDE11,
PDE2A,
PDE3A,
PDE3B,
PDE4,
PDE4,
PDE4,
PDE4,
PDE7,
PDE7,
PDE8,
PDE8 💬 		23件: Alcoholism, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Cortisol synthesis and secretion, Cushing syndrome, Glucagon signaling pathway, Insulin signaling pathway, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Progesterone-mediated oocyte maturation, Purine metabolism, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Taste transduction, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 63 💬
4 Amoxicillin 2件: Amoxicilina; Amoxicillin3件: Amoxicillin ,
Amoxicillin sodium ,
Amoxicillin 💬 		--6件: 19, 46, 63, 96, 97, 299 💬
5 Atorvastatin 2件: Atorvastatin; Atorvastatin calcium2件: Atorvastatin calcium ,
Atorvastatin 💬 		1件: HMGCR 💬 3件: AMPK signaling pathway, Bile secretion, Terpenoid backbone biosynthesis 💬20件: 13, 22, 46, 49, 51, 58, 63, 67, 79, 84, 88, 93, 96, 97, 160, 225, 265, 271, 297, 299 💬
6 Avatrombopag 2件: Avatrombopag; Avatrombopag maleate2件: Avatrombopag ,
Avatrombopag maleate 💬 		1件: TPOR 💬 3件: Cytokine-cytokine receptor interaction, Hormone signaling, JAK-STAT signaling pathway 💬2件: 60, 63 💬
7 Azathioprine 2件: Azathioprine; Azatioprina2件: Azathioprine ,
Azathioprine sodium 💬 		--22件: 6, 11, 13, 19, 35, 42, 43, 44, 45, 46, 49, 55, 63, 65, 66, 84, 85, 94, 95, 96, 97, 162 💬
8 Belimumab 1件: Belimumab1件: Belimumab 💬 1件: TNFSF13B 💬 4件: Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis 💬14件: 11, 13, 43, 44, 46, 48, 49, 51, 53, 63, 66, 95, 222, 296 💬
9 Bevifimod 1件: Staphylococcal protein A---1件: 63 💬
10 Blisibimod 1件: Blisibimod1件: Blisibimod 💬 --5件: 43, 44, 49, 63, 66 💬
11 Bortezomib 1件: Bortezomib1件: Bortezomib 💬 1件: PSMB5 💬 8件: Alzheimer disease, Amyotrophic lateral sclerosis, Huntington disease, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Prion disease, Proteasome, Spinocerebellar ataxia 💬18件: 11, 13, 26, 28, 46, 49, 51, 61, 63, 64, 66, 172, 222, 228, 256, 283, 288, 331 💬
12 Caplacizumab 1件: Caplacizumab1件: Caplacizumab 💬 1件: VWF 💬 8件: Complement and coagulation cascades, Coronavirus disease - COVID-19, ECM-receptor interaction, Focal adhesion, Human papillomavirus infection, Neutrophil extracellular trap formation, PI3K-Akt signaling pathway, Platelet activation 💬2件: 63, 64 💬
13 Clarithromycin 1件: Clarithromycin1件: Clarithromycin 💬 --9件: 6, 13, 46, 63, 84, 96, 97, 228, 299 💬
14 Cyclosporine 6件: Ciclosporin; Ciclosporina; Ciclosporine; Cyclosporin; Cyclosporin A; Cyclosporine1件: Cyclosporine 💬 5件: PPP3C,
PPP3C,
PPP3C,
PPP3R,
PPP3R 💬 		33件: Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬42件: 11, 19, 20, 26, 28, 36, 40, 41, 42, 45, 46, 49, 50, 53, 54, 55, 56, 58, 60, 61, 62, 63, 64, 65, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
15 Danazol 1件: Danazol1件: Danazol 💬 3件: AR,
ESR1,
PGR 💬 		12件: Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Estrogen signaling pathway, Hormone signaling, Oocyte meiosis, Pathways in cancer, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Prostate cancer, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬5件: 60, 63, 64, 65, 285 💬
16 Daratumumab 1件: Daratumumab1件: Daratumumab 💬 1件: CD38 💬 6件: Calcium signaling pathway, Hematopoietic cell lineage, Nicotinate and nicotinamide metabolism, Oxytocin signaling pathway, Pancreatic secretion, Salivary secretion 💬10件: 13, 16, 28, 46, 48, 49, 60, 63, 288, 331 💬
17 Decitabine 1件: Decitabine1件: Decitabine 💬 3件: DNMT1,
DNMT3A,
DNMT3B 💬 		3件: Cysteine and methionine metabolism, Efferocytosis, MicroRNAs in cancer 💬3件: 13, 60, 63 💬
18 Dexamethasone 2件: Dexamethasone; Dexamethasone sodium phosphate3件: Dexamethasone ,
Dexamethasone sodium phosphate ,
Dexamethasone phosphate 💬 		1件: NR3C1 💬 1件: Neuroactive ligand-receptor interaction 💬25件: 13, 14, 16, 19, 28, 35, 53, 63, 64, 65, 70, 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 296, 299, 331 💬
19 Dexamethasone palmitate 1件: Dexamethasone palmitate1件: Dexamethasone palmitate 💬 1件: NR3C1 💬 1件: Neuroactive ligand-receptor interaction 💬1件: 63 💬
20 Efgartigimod alfa 1件: Efgartigimod alfa1件: Efgartigimod alfa 💬 --7件: 11, 13, 14, 35, 53, 63, 162 💬
21 Eltrombopag 2件: Eltrombopag; Eltrombopag olamine2件: Eltrombopag olamine ,
Eltrombopag choline 💬 		1件: TPOR 💬 3件: Cytokine-cytokine receptor interaction, Hormone signaling, JAK-STAT signaling pathway 💬5件: 60, 63, 65, 284, 285 💬
22 Ethanolamine 1件: Ethanolamine1件: Monoethanolamine 💬 --2件: 63, 279 💬
23 Fecal microbiota 1件: Fecal microbiota---12件: 2, 6, 13, 49, 63, 66, 93, 94, 96, 97, 99, 271 💬
24 Fostamatinib 2件: Fostamatinib; Fostamatinib disodium2件: Fostamatinib ,
Fostamatinib disodium 💬 		1件: SYK 💬 17件: B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Coronavirus disease - COVID-19, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagocytosis, Herpes simplex virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, NF-kappa B signaling pathway, Natural killer cell mediated cytotoxicity, Neutrophil extracellular trap formation, Osteoclast differentiation, PI3K-Akt signaling pathway, Phospholipase D signaling pathway, Platelet activation, Tuberculosis, Viral carcinogenesis 💬5件: 46, 49, 61, 63, 66 💬
25 Glycyrrhiza glabra 1件: Glycyrrhiza---3件: 53, 63, 97 💬
26 Hetrombopag 1件: Hetrombopag---2件: 60, 63 💬
27 Human immunoglobulin G 6件: Human immunoglobulin G; Human normal immunoglobulin; Immune globulin; Immunoglobulin; Immunoglobulin G; Intravenous immunoglobulin1件: Globulin, immune 💬 --9件: 11, 13, 14, 43, 45, 50, 51, 63, 65 💬
28 Hydroxychloroquine 2件: Hydroxychloroquine; Hydroxychloroquine sulfate2件: Hydroxychloroquine sulfate ,
Hydroxychloroquine 💬 		--27件: 6, 13, 34, 41, 43, 44, 45, 46, 48, 49, 53, 56, 63, 66, 84, 90, 96, 97, 107, 218, 222, 224, 234, 254, 271, 298, 299 💬
29 Ianalumab 1件: Ianalumab1件: Ianalumab 💬 1件: TNFRSF13C 💬 5件: Cytokine-cytokine receptor interaction, Human T-cell leukemia virus 1 infection, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Primary immunodeficiency 💬8件: 35, 46, 49, 51, 53, 61, 63, 95 💬
30 Lansoprazole 1件: Lansoprazole1件: Lansoprazole 💬 2件: ATP4A,
ATP4B 💬 		3件: Collecting duct acid secretion, Gastric acid secretion, Oxidative phosphorylation 💬6件: 63, 71, 85, 166, 222, 299 💬
31 Lusutrombopag 1件: Lusutrombopag1件: Lusutrombopag 💬 1件: TPOR 💬 3件: Cytokine-cytokine receptor interaction, Hormone signaling, JAK-STAT signaling pathway 💬2件: 60, 63 💬
32 Methylprednisolone 3件: Methylprednisolon; Methylprednisolone; Methylprednisolone acetate2件: Methylprednisolone ,
Methylprednisolone acetate 💬 		1件: NR3C1 💬 1件: Neuroactive ligand-receptor interaction 💬48件: 2, 6, 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 95, 96, 97, 127, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296, 300 💬
33 Metronidazole 2件: Metronidazol; Metronidazole2件: Metronidazole ,
Metronidazole hydrochloride 💬 		--7件: 46, 51, 63, 94, 96, 97, 291 💬
34 Mezagitamab 1件: Mezagitamab1件: Mezagitamab 💬 1件: CD38 💬 6件: Calcium signaling pathway, Hematopoietic cell lineage, Nicotinate and nicotinamide metabolism, Oxytocin signaling pathway, Pancreatic secretion, Salivary secretion 💬2件: 63, 66 💬
35 Montelukast 2件: Montelukast; Montelukast sodium2件: Montelukast sodium ,
Montelukast 💬 		1件: CYSLTR1 💬 2件: Calcium signaling pathway, Neuroactive ligand-receptor interaction 💬9件: 6, 13, 19, 46, 61, 63, 85, 98, 228 💬
36 Mycophenolate mofetil 1件: Mycophenolate mofetil2件: Mycophenolate mofetil ,
Mycophenolate mofetil hydrochloride 💬 		2件: IMPDH,
IMPDH 💬 		2件: Drug metabolism - other enzymes, Purine metabolism 💬34件: 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 93, 95, 96, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬
37 Mycophenolic acid 5件: Acido micofenolico; Micofenolico acido; Mycophenolate; Mycophenolate sodium; Mycophenolic acid2件: Mycophenolate sodium ,
Mycophenolic acid 💬 		2件: IMPDH,
IMPDH 💬 		2件: Drug metabolism - other enzymes, Purine metabolism 💬37件: 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 84, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 💬
38 Natural Killer Cell 1件: NK cells---3件: 26, 49, 63 💬
39 Nicotinamide 2件: Niacinamide; Nicotinamide1件: Niacinamide 💬 --20件: 2, 5, 6, 7, 8, 13, 17, 18, 21, 46, 49, 60, 63, 65, 67, 85, 97, 107, 162, 191 💬
40 Obinutuzumab 1件: Obinutuzumab1件: Obinutuzumab 💬 1件: MS4A1 💬 1件: Hematopoietic cell lineage 💬5件: 43, 44, 49, 63, 222 💬
41 Orelabrutinib 1件: Orelabrutinib1件: Orelabrutinib 💬 1件: BTK 💬 7件: B cell receptor signaling pathway, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, NF-kappa B signaling pathway, Osteoclast differentiation, Platelet activation, Primary immunodeficiency 💬4件: 13, 49, 61, 63 💬
42 Povetacicept 1件: Povetacicept1件: Povetacicept 💬 1件: TNFRSF13B 💬 3件: Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, Primary immunodeficiency 💬3件: 61, 63, 222 💬
43 Prednisolone 3件: Prednisolona; Prednisolone; Prednisolonum1件: Prednisolone 💬 1件: NR3C1 💬 1件: Neuroactive ligand-receptor interaction 💬41件: 3, 11, 13, 14, 18, 25, 26, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 54, 56, 60, 61, 63, 64, 66, 81, 84, 85, 95, 96, 97, 113, 145, 162, 222, 251, 269, 271, 296, 299, 300 💬
44 Prednisone 2件: Prednisona; Prednisone1件: Prednisone 💬 1件: NR3C1 💬 1件: Neuroactive ligand-receptor interaction 💬54件: 2, 11, 13, 14, 18, 19, 26, 28, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 60, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 90, 93, 95, 96, 97, 113, 145, 162, 164, 205, 222, 224, 228, 251, 269, 283, 285, 288, 299, 300, 303, 307, 331 💬
45 Prednisone acetate 2件: Cortancyl; Prednisone acetate1件: Prednisone acetate 💬 1件: NR3C1 💬 1件: Neuroactive ligand-receptor interaction 💬9件: 35, 40, 41, 46, 49, 63, 162, 222, 224 💬
46 PRTX-100 1件: PRTX-100---2件: 46, 63 💬
47 Recombinant Human Thrombopoietin 2件: Recombinant human thrombopoietin; Rhtpo---2件: 60, 63 💬
48 Rilzabrutinib 1件: Rilzabrutinib1件: Rilzabrutinib 💬 1件: BTK 💬 7件: B cell receptor signaling pathway, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, NF-kappa B signaling pathway, Osteoclast differentiation, Platelet activation, Primary immunodeficiency 💬5件: 35, 61, 63, 222, 300 💬
49 Rituximab 1件: Rituximab1件: Rituximab 💬 1件: MS4A1 💬 1件: Hematopoietic cell lineage 💬52件: 11, 13, 14, 19, 26, 34, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 55, 56, 60, 61, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 162, 172, 220, 222, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331 💬
50 Romiplostim 1件: Romiplostim1件: Romiplostim 💬 1件: TPOR 💬 3件: Cytokine-cytokine receptor interaction, Hormone signaling, JAK-STAT signaling pathway 💬4件: 60, 63, 64, 65 💬
51 Rozanolixizumab 2件: Rozanolixizumab; UCB76651件: Rozanolixizumab 💬 --3件: 11, 14, 63 💬
52 Sirolimus 2件: Rapamycin; Sirolimus1件: Sirolimus 💬 1件: MTOR 💬 49件: AMPK signaling pathway, Acute myeloid leukemia, Adipocytokine signaling pathway, Alzheimer disease, Amyotrophic lateral sclerosis, Apelin signaling pathway, Autophagy - animal, Autophagy - other, Breast cancer, Cellular senescence, Central carbon metabolism in cancer, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Diabetic cardiomyopathy, ErbB signaling pathway, Gastric cancer, Glioma, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatocellular carcinoma, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Huntington disease, Insulin resistance, Insulin signaling pathway, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Longevity regulating pathway, Longevity regulating pathway - multiple species, MicroRNAs in cancer, Neutrophil extracellular trap formation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Shigellosis, Spinocerebellar ataxia, Th17 cell differentiation, Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus, mTOR signaling pathway 💬46件: 2, 6, 13, 15, 17, 19, 21, 34, 35, 36, 46, 48, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 97, 98, 137, 157, 158, 192, 193, 222, 227, 256, 277, 278, 279, 280, 281, 283, 285, 300, 331 💬
53 Telitacicept 1件: Telitacicept---11件: 11, 13, 46, 48, 49, 51, 53, 63, 66, 222, 300 💬
54 Teriflunomide 1件: Teriflunomide1件: Teriflunomide 💬 1件: DHODH 💬 1件: Pyrimidine metabolism 💬4件: 13, 25, 26, 63 💬
55 Thrombopoietin 1件: Thrombopoietin---3件: 47, 61, 63 💬
56 Toralizumab 1件: ANTI-CD40L1件: Toralizumab 💬 1件: TNFSF5 💬 14件: Allograft rejection, Asthma, Autoimmune thyroid disease, Cell adhesion molecules, Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, Lipid and atherosclerosis, Malaria, NF-kappa B signaling pathway, Primary immunodeficiency, Systemic lupus erythematosus, T cell receptor signaling pathway, Toxoplasmosis, Viral myocarditis 💬1件: 63 💬
57 Tretinoin 3件: Atra; Tretinoin; Tretinoina1件: Tretinoin 💬 3件: PML,
RARA,
RARB 💬 		12件: Acute myeloid leukemia, Endocytosis, Estrogen signaling pathway, Gastric cancer, Herpes simplex virus 1 infection, Influenza A, Non-small cell lung cancer, Pathways in cancer, Small cell lung cancer, Th17 cell differentiation, Transcriptional misregulation in cancer, Ubiquitin mediated proteolysis 💬6件: 2, 62, 63, 75, 94, 231 💬
58 Veltuzumab 1件: Veltuzumab1件: Veltuzumab 💬 1件: MS4A1 💬 1件: Hematopoietic cell lineage 💬2件: 46, 63 💬
59 Vinblastine 2件: Vinblastine; Vinblastine sulfate2件: Vinblastine sulfate ,
Vinblastine 💬 		9件: TUBB,
TUBB,
TUBB,
TUBB,
TUBB,
TUBB,
TUBB,
TUBB,
TUBB 💬 		11件: Alzheimer disease, Amyotrophic lateral sclerosis, Gap junction, Huntington disease, Motor proteins, Parkinson disease, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Phagosome, Prion disease, Salmonella infection 💬3件: 34, 63, 65 💬
60 Von Willebrand factor human 3件: Factor VON willebrand; Human VON willebrand factor; VON willebrand factor---2件: 63, 288 💬
61 Vonoprazan 1件: Vonoprazan1件: Vonoprazan 💬 2件: ATP4A,
ATP4B 💬 		3件: Collecting duct acid secretion, Gastric acid secretion, Oxidative phosphorylation 💬3件: 63, 97, 98 💬
62 Water 1件: Water1件: Water 💬 --28件: 2, 5, 6, 13, 17, 19, 22, 35, 46, 51, 53, 56, 57, 63, 64, 66, 67, 72, 85, 96, 97, 206, 225, 226, 230, 274, 278, 299 💬
63 Zanubrutinib 1件: Zanubrutinib1件: Zanubrutinib 💬 1件: BTK 💬 7件: B cell receptor signaling pathway, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, NF-kappa B signaling pathway, Osteoclast differentiation, Platelet activation, Primary immunodeficiency 💬6件: 13, 61, 63, 222, 300, 331 💬
64 ZUBERITAMAB 1件: Zuberitamab---2件: 63, 222 💬