Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. KEGG DRUG DrugBank 薬物名（臨床試験情報から抽出） KEGG GENES KEGG PATHWAY 指定難病告示番号
1 Leucine 💬1件: Leucine2件: L-leucine; Leucine--6件: 6, 19, 65, 283, 284, 299 💬
2 Cholesterol 💬1件: Cholesterol1件: Cholesterol--6件: 8, 19, 90, 160, 222, 310 💬
3 Gelatin 💬1件: Gelatin3件: Gelatin; Gelatine; Sulfur Colloid--7件: 19, 28, 62, 78, 97, 269, 299 💬
4 Methotrexate 💬1件: Methotrexate6件: Methotrexat; Methotrexate; METHOTREXATE SODIUM; Metoject; Metotrexato; Méthotrexate2件: DHFR,
DHFR2 💬 		5件: Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬38件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬
5 Angiotensin II 💬1件: Angiotensin II2件: Angiotensin; Angiotensin II2件: AGTR1,
AGTR2 💬 		16件: AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬7件: 17, 19, 46, 66, 86, 222, 224 💬
6 Cyclosporine 💬1件: Cyclosporine10件: Ciclosporin; Ciclosporina; Ciclosporine; Cyclosporin; Cyclosporin A; Cyclosporine; Cyclosporine A; Ikervis; Neoral; RESTASIS5件: PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬 		33件: Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
7 Cholecalciferol 💬1件: Cholecalciferol5件: Cholecalciferol; COLECALCIFEROL; Multivitamin; Vitamin D; Vitamin D31件: VDR 💬 5件: Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬16件: 6, 13, 19, 20, 34, 46, 49, 51, 53, 60, 65, 96, 97, 228, 298, 299 💬
8 Acetylcysteine 💬1件: Acetylcysteine3件: ACETYLCYSTEINE; Mucomyst; N-acetylcysteine--21件: 6, 13, 19, 20, 21, 49, 51, 53, 58, 63, 85, 90, 94, 111, 164, 193, 233, 296, 298, 299, 337 💬
9 Amoxicillin 💬1件: Amoxicillin4件: Amoxicilina; Amoxicillin; Amoxycillin; Augmentin--7件: 6, 46, 63, 96, 97, 222, 299 💬
10 Azathioprine 💬1件: Azathioprine3件: Azathioprine; Azatioprina; Imuran--21件: 6, 11, 13, 19, 35, 42, 43, 44, 45, 46, 49, 63, 65, 66, 85, 93, 94, 95, 96, 97, 162 💬
11 Busulfan 💬1件: Busulfan3件: BUSILVEX; Busulfan; BUSULFANO--13件: 19, 20, 28, 36, 49, 51, 60, 65, 164, 274, 284, 285, 326 💬
12 Cyclophosphamide 💬1件: Cyclophosphamide6件: Ciclofosfamida; Ciclofosfamide; Cyclophosphamid; Cyclophosphamide; Cyclophosphamidum; Cytoxan--44件: 11, 13, 14, 16, 19, 20, 26, 28, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 56, 60, 62, 65, 66, 84, 85, 93, 96, 162, 164, 172, 205, 222, 224, 256, 274, 283, 284, 285, 288, 326, 331 💬
13 Gabapentin 💬1件: Gabapentin4件: Gabapentin; GABAPENTINA; Gabapentine; NEURONTIN5件: CACNA2D1,
CACNA2D2,
CACNA2D3,
CACNA2D4,
SLC6A1 💬 		9件: Adrenergic signaling in cardiomyocytes, Arrhythmogenic right ventricular cardiomyopathy, Cardiac muscle contraction, Dilated cardiomyopathy, GABAergic synapse, Hypertrophic cardiomyopathy, MAPK signaling pathway, Oxytocin signaling pathway, Synaptic vesicle cycle 💬5件: 6, 13, 19, 70, 298 💬
14 Hydroxyurea 💬1件: Hydroxyurea1件: Hydroxyurea1件: RRM2 💬 7件: Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Nucleotide metabolism, Purine metabolism, Pyrimidine metabolism, p53 signaling pathway 💬8件: 3, 13, 19, 20, 65, 85, 86, 284 💬
15 Lisinopril 💬1件: Lisinopril2件: Lisinopril; Zestril1件: ACE 💬 6件: Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬7件: 19, 46, 49, 66, 67, 113, 222 💬
16 Melphalan 💬1件: Melphalan3件: ALKERAN; Melphalan; Melphalan Hydrochloride--15件: 11, 13, 14, 19, 20, 28, 60, 62, 65, 96, 164, 234, 284, 285, 299 💬
17 Methylprednisolone 💬1件: Methylprednisolone4件: Medrol; Methylprednisolon; Methylprednisolone; Methylprednisolone acetate1件: NR3C1 💬 1件: Neuroactive ligand-receptor interaction 💬46件: 2, 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 95, 96, 97, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296 💬
18 Prednisone 💬1件: Prednisone3件: PREDNISONA; PREDNISONE; RAYOS1件: NR3C1 💬 1件: Neuroactive ligand-receptor interaction 💬45件: 2, 11, 13, 14, 19, 26, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 95, 96, 97, 113, 162, 164, 205, 222, 224, 228, 283, 284, 288, 299, 300, 307, 331 💬
19 Pyrimethamine 💬1件: Pyrimethamine2件: Daraprim; PYRIMETHAMINE--4件: 2, 4, 19, 65 💬
20 Thiotepa 💬1件: Thiotepa1件: Thiotepa--12件: 13, 19, 20, 28, 51, 60, 65, 85, 96, 164, 284, 285 💬
21 Mycophenolate mofetil 💬1件: Mycophenolate mofetil3件: CellCept; Mycophenolate mofetil; Mycophenolate mofetil TEVA2件: IMPDH1,
IMPDH2 💬 		4件: Drug metabolism - other enzymes, Metabolic pathways, Nucleotide metabolism, Purine metabolism 💬34件: 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬
22 Sirolimus 💬1件: Sirolimus3件: Rapamune; Rapamycin; SIROLIMUS1件: MTOR 💬 51件: AMPK signaling pathway, Acute myeloid leukemia, Adipocytokine signaling pathway, Alzheimer disease, Amyotrophic lateral sclerosis, Apelin signaling pathway, Autophagy - animal, Autophagy - other, Breast cancer, Cellular senescence, Central carbon metabolism in cancer, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Diabetic cardiomyopathy, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, ErbB signaling pathway, Gastric cancer, Glioma, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatocellular carcinoma, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Huntington disease, Insulin resistance, Insulin signaling pathway, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Longevity regulating pathway, Longevity regulating pathway - multiple species, MicroRNAs in cancer, Neutrophil extracellular trap formation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Shigellosis, Spinocerebellar ataxia, Th17 cell differentiation, Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus, mTOR signaling pathway 💬40件: 2, 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
23 Paricalcitol 💬1件: Paricalcitol1件: Paricalcitol1件: VDR 💬 5件: Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬5件: 19, 66, 218, 238, 298 💬
24 Calcium carbonate 💬1件: Calcium carbonate3件: Calcio carbonato; Calcium; Calcium carbonate--9件: 13, 19, 46, 53, 75, 96, 235, 274, 299 💬
25 Iohexol 💬1件: Iohexol2件: Iohexol; OMNIPAQUE--3件: 19, 67, 222 💬
26 Angiotensin II 💬1件: Angiotensin II2件: Angiotensin; Angiotensin II2件: AGTR1,
AGTR2 💬 		16件: AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬7件: 17, 19, 46, 66, 86, 222, 224 💬
27 Lysine 💬1件: Lysine1件: Lysine--4件: 13, 97, 228, 299 💬
28 Betadex 💬1件: Betadex1件: Beta-cyclodextrin--1件: 19 💬
29 Adalimumab 💬1件: Adalimumab7件: Adalimumab; Amgevita; Cyltezo; Hulio; Humira; Hyrimoz; Imraldi1件: TNF 💬 67件: AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
30 Agalsidase alfa 💬1件: Agalsidase alfa5件: AGALSIDASE ALFA; Agalsidase Alpha; Alpha-galactosidase A; Recombinant alpha-galactosidase A; REPLAGAL1件: GLA 💬 6件: Galactose metabolism, Glycerolipid metabolism, Glycosphingolipid biosynthesis - globo and isoglobo series, Lysosome, Metabolic pathways, Sphingolipid metabolism 💬1件: 19 💬
31 Alemtuzumab 💬1件: Alemtuzumab4件: Alemtuzumab; Campath; Lemtrada; MABCAMPATH1件: CD52 💬 1件: 💬22件: 13, 15, 19, 20, 36, 43, 44, 46, 49, 51, 60, 62, 63, 65, 85, 96, 164, 234, 283, 284, 285, 326 💬
32 Alglucerase 💬1件: Alglucerase1件: Ceredase1件: GBA1 💬 4件: Lysosome, Metabolic pathways, Other glycan degradation, Sphingolipid metabolism 💬1件: 19 💬
33 Rituximab 💬1件: Rituximab6件: MabThera; Rituxan; RITUXIMAB; Rixathon; Ruxience; TRUXIMA1件: MS4A1 💬 1件: Hematopoietic cell lineage 💬48件: 11, 13, 14, 19, 26, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 55, 56, 60, 61, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 162, 222, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331 💬
34 Imiglucerase 💬1件: Imiglucerase3件: CEREZYME; IMIGLUCERASA; IMIGLUCERASE1件: GBA1 💬 4件: Lysosome, Metabolic pathways, Other glycan degradation, Sphingolipid metabolism 💬1件: 19 💬
35 Abatacept 💬1件: Abatacept2件: ABATACEPT; Orencia2件: CD80,
CD86 💬 		13件: Allograft rejection, Autoimmune thyroid disease, Cell adhesion molecules, Graft-versus-host disease, Intestinal immune network for IgA production, Kaposi sarcoma-associated herpesvirus infection, Rheumatoid arthritis, Systemic lupus erythematosus, Toll-like receptor signaling pathway, Transcriptional misregulation in cancer, Type I diabetes mellitus, Viral myocarditis, Virion - Adenovirus 💬26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
36 Agalsidase beta 💬1件: Agalsidase beta2件: AGALSIDASE BETA; FABRAZYME1件: GLA 💬 6件: Galactose metabolism, Glycerolipid metabolism, Glycosphingolipid biosynthesis - globo and isoglobo series, Lysosome, Metabolic pathways, Sphingolipid metabolism 💬1件: 19 💬
37 Lenograstim 💬1件: Lenograstim2件: G-CSF; Lenograstim1件: CSF3R 💬 5件: Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer 💬7件: 2, 13, 16, 18, 19, 57, 65 💬
38 Lactase 💬1件: Tilactase1件: Beta-Galactosidase--1件: 19 💬
39 Clofarabine 💬1件: Clofarabine1件: Clofarabine3件: POLA1,
POLA2,
RRM1 💬 		7件: DNA replication, Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Nucleotide metabolism, Purine metabolism, Pyrimidine metabolism 💬5件: 19, 20, 60, 234, 326 💬
40 Cysteamine 💬1件: Cysteamine8件: 2-aminoethanethiol; Beta-Mercaptoethylamine; CYSTADROPS; CYSTAGON; CYSTEAMINE; Mercaptamina; Mercaptamine; PROCYSBI--4件: 8, 19, 21, 299 💬
41 Quinapril 💬1件: Quinapril1件: Accuretic1件: ACE 💬 6件: Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬1件: 19 💬
42 Idursulfase 💬1件: Idursulfase4件: Elaprase; Iduronate 2-sulfatase; IDURSULFASA; IDURSULFASE1件: IDS 💬 3件: Glycosaminoglycan degradation, Lysosome, Metabolic pathways 💬1件: 19 💬
43 Laronidase 💬1件: Laronidase2件: Aldurazyme; LARONIDASE1件: IDUA 💬 3件: Glycosaminoglycan degradation, Lysosome, Metabolic pathways 💬2件: 19, 256 💬
44 Miglustat 💬1件: Miglustat2件: Miglustat; Zavesca1件: UGCG 💬 2件: Metabolic pathways, Sphingolipid metabolism 💬3件: 19, 256, 299 💬
45 Mycophenolic acid 💬1件: Mycophenolic acid5件: Acido Micofenolico; MICOFENOLICO ACIDO; Mycophenolate; Mycophenolic acid; Myfortic2件: IMPDH1,
IMPDH2 💬 		4件: Drug metabolism - other enzymes, Metabolic pathways, Nucleotide metabolism, Purine metabolism 💬36件: 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 84, 85, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 💬
46 Galsulfase 💬1件: Galsulfase2件: GALSULFASE; Naglazyme1件: ARSB 💬 3件: Glycosaminoglycan degradation, Lysosome, Metabolic pathways 💬1件: 19 💬
47 Donkey glue 💬1件: Gelatin3件: Gelatin; Gelatine; Sulfur Colloid--7件: 19, 28, 62, 78, 97, 269, 299 💬
48 Alendronic acid 💬1件: Alendronic acid3件: Alendronate; Alendronate sodium; Alendronic acid1件: FDPS 💬 4件: Human T-cell leukemia virus 1 infection, Influenza A, Metabolic pathways, Terpenoid backbone biosynthesis 💬7件: 19, 41, 46, 50, 271, 274, 299 💬
49 Gamolenic acid 💬1件: Gamolenic acid2件: Gamma-Linolenic acid; Linolenic acid--1件: 46 💬
50 Treosulfan 💬1件: Treosulfan2件: OVASTAT; TREOSULFAN--6件: 13, 19, 62, 65, 283, 286 💬
51 Ambroxol 💬1件: Ambroxol1件: Ambroxol--2件: 6, 19 💬
52 Amoxicillin 💬1件: Amoxicillin4件: Amoxicilina; AMOXICILLIN; Amoxycillin; Augmentin--7件: 6, 46, 63, 96, 97, 222, 299 💬
53 Betaine 💬1件: Betaine2件: Betaine; Cystadane--3件: 19, 201, 337 💬
54 Cyclophosphamide 💬1件: Cyclophosphamide6件: Ciclofosfamida; Ciclofosfamide; Cyclophosphamid; Cyclophosphamide; Cyclophosphamidum; Cytoxan--44件: 11, 13, 14, 16, 19, 20, 26, 28, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 56, 60, 62, 65, 66, 84, 85, 93, 96, 162, 164, 172, 205, 222, 224, 256, 274, 283, 284, 285, 288, 326, 331 💬
55 Enalapril 💬1件: Enalapril2件: Enalapril; Enalapril Maleate1件: ACE 💬 6件: Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬6件: 19, 46, 66, 113, 210, 222 💬
56 Fludarabine 💬1件: Fludarabine4件: FLUDARA; Fludarabina; Fludarabine; Fludarabine phosphate1件: RRM1 💬 6件: Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Nucleotide metabolism, Purine metabolism, Pyrimidine metabolism 💬20件: 11, 13, 19, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 286, 326 💬
57 Folinic acid 💬1件: Leucovorin2件: Folinic acid; Leucovorin--4件: 19, 46, 107, 320 💬
58 Folinic acid calcium salt pentahydrate 💬1件: Leucovorin2件: Folinic acid; Leucovorin--4件: 19, 46, 107, 320 💬
59 Levothyroxine 💬1件: Levothyroxine2件: Levothyroxine; Thyroxine2件: THRA,
THRB 💬 		2件: Neuroactive ligand-receptor interaction, Thyroid hormone signaling pathway 💬4件: 19, 49, 78, 80 💬
60 Lisinopril 💬1件: Lisinopril2件: Lisinopril; Zestril1件: ACE 💬 6件: Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬7件: 19, 46, 49, 66, 67, 113, 222 💬
61 Losartan 💬1件: Losartan3件: Cozaar; Losartan; LOSARTAN POTASSIUM1件: AGTR1 💬 16件: AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬17件: 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
62 Warfarin 💬1件: Warfarin2件: Warfarin; Warfarin Sodium2件: NQO1,
VKORC1 💬 		7件: Biosynthesis of cofactors, Chemical carcinogenesis - reactive oxygen species, Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Metabolic pathways, Pathways in cancer, Ubiquinone and other terpenoid-quinone biosynthesis 💬11件: 6, 8, 13, 19, 46, 49, 66, 85, 86, 88, 91 💬
63 Dapagliflozin 💬1件: Dapagliflozin2件: Dapagliflozin; Forxiga1件: SLC5A2 💬 1件: 💬7件: 19, 49, 66, 67, 86, 88, 222 💬
64 Plerixafor 💬1件: Plerixafor2件: Mozobil; Plerixafor1件: CXCR4 💬 14件: Axon guidance, Calcium signaling pathway, Chemokine signaling pathway, Cytokine-cytokine receptor interaction, Endocytosis, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Intestinal immune network for IgA production, Leukocyte transendothelial migration, Pathways in cancer, Regulation of actin cytoskeleton, Viral life cycle - HIV-1, Viral protein interaction with cytokine and cytokine receptor, Virion - Human immunodeficiency virus 💬5件: 19, 20, 65, 285, 299 💬
65 Velaglucerase alfa 💬1件: Velaglucerase alfa3件: GA-GCB; VELAGLUCERASE ALFA; VPRIV1件: GBA1 💬 4件: Lysosome, Metabolic pathways, Other glycan degradation, Sphingolipid metabolism 💬1件: 19 💬
66 Ataluren 💬1件: Ataluren2件: Ataluren; Translarna--6件: 19, 113, 140, 246, 299, 329 💬
67 Afegostat 💬1件: Afegostat1件: Afegostat--1件: 19 💬
68 Taliglucerase alfa 💬1件: Taliglucerase alfa3件: Elelyso; PrGCD; TALIGLUCERASE ALFA1件: GBA1 💬 4件: Lysosome, Metabolic pathways, Other glycan degradation, Sphingolipid metabolism 💬1件: 19 💬
69 Eliglustat 💬1件: Eliglustat2件: Cerdelga; Eliglustat1件: UGCG 💬 2件: Metabolic pathways, Sphingolipid metabolism 💬1件: 19 💬
70 Elosulfase alfa 💬1件: Elosulfase alfa3件: Elosulfase alfa; Recombinant human N-acetylgalactosamine-6-sulfatase; RhGALNS1件: GALNS 💬 3件: Glycosaminoglycan degradation, Lysosome, Metabolic pathways 💬1件: 19 💬
71 Migalastat 💬1件: Migalastat3件: 1-Deoxygalactonojirimycin; Galafold; MIGALASTAT--1件: 19 💬
72 Sofosbuvir 💬1件: Sofosbuvir1件: Sofosbuvir--1件: 19 💬
73 Sebelipase alfa 💬1件: Sebelipase alfa4件: KANUMA; SBC-102; Sebelipasa Alfa; Sebelipase Alfa1件: LIPA 💬 3件: Cholesterol metabolism, Lysosome, Steroid biosynthesis 💬1件: 19 💬
74 Ledipasvir 💬1件: Ledipasvir1件: Ledipasvir--1件: 19 💬
75 Calcium carbonate 💬1件: Calcium carbonate3件: Calcio carbonato; Calcium; Calcium Carbonate--9件: 13, 19, 46, 53, 75, 96, 235, 274, 299 💬
76 Cerliponase alfa 💬1件: Cerliponase alfa2件: Brineura; Cerliponase Alfa1件: TPP1 💬 1件: Lysosome 💬1件: 19 💬
77 Olipudase alfa 💬1件: Olipudase alfa1件: OLIPUDASE ALFA1件: SMPD1 💬 5件: Lysosome, Metabolic pathways, Necroptosis, Sphingolipid metabolism, Sphingolipid signaling pathway 💬1件: 19 💬
78 Vestronidase alfa 💬1件: Vestronidase alfa3件: Mepsevii; Recombinant human beta-glucuronidase; Vestronidase alfa1件: GUSB 💬 8件: Ascorbate and aldarate metabolism, Biosynthesis of cofactors, Drug metabolism - other enzymes, Glycosaminoglycan degradation, Lysosome, Metabolic pathways, Pentose and glucuronate interconversions, Porphyrin metabolism 💬1件: 19 💬
79 Velmanase alfa 💬1件: Velmanase alfa3件: LAMAZYM; RhLAMAN; VELMANASE ALFA1件: MAN2B1 💬 2件: Lysosome, Other glycan degradation 💬1件: 19 💬
80 Idursulfase beta 💬1件: Idursulfase beta3件: Hunterase; Iduronate 2-sulfatase; Idursulfase beta1件: IDS 💬 3件: Glycosaminoglycan degradation, Lysosome, Metabolic pathways 💬1件: 19 💬
81 Rimiducid 💬1件: Rimiducid1件: Rimiducid1件: CASP9 💬 35件: Alzheimer disease, Amyotrophic lateral sclerosis, Apoptosis, Apoptosis - multiple species, Colorectal cancer, Endometrial cancer, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Huntington disease, Influenza A, Kaposi sarcoma-associated herpesvirus infection, Legionellosis, Lipid and atherosclerosis, Measles, Non-small cell lung cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Parkinson disease, Pathogenic Escherichia coli infection, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platinum drug resistance, Prion disease, Prostate cancer, Small cell lung cancer, Thyroid hormone signaling pathway, Toxoplasmosis, Tuberculosis, VEGF signaling pathway, Viral myocarditis, p53 signaling pathway 💬6件: 19, 60, 65, 284, 285, 326 💬
82 Arimoclomol 💬1件: Arimoclomol1件: ARIMOCLOMOL--3件: 2, 15, 19 💬
83 Lucerastat 💬1件: Lucerastat1件: Lucerastat1件: UGCG 💬 2件: Metabolic pathways, Sphingolipid metabolism 💬1件: 19 💬
84 Venglustat 💬1件: Venglustat2件: GENZ-682452; Venglustat1件: UGCG 💬 2件: Metabolic pathways, Sphingolipid metabolism 💬3件: 6, 19, 67 💬
85 Genistein 💬1件: Genistein1件: GENISTEIN--2件: 19, 299 💬
86 Pegunigalsidase alfa 💬1件: Pegunigalsidase alfa1件: PEGUNIGALSIDASE ALFA--1件: 19 💬
87 Pabinafusp alfa 💬1件: Pabinafusp alfa1件: Pabinafusp alfa2件: IDS,
TFRC 💬 		8件: Endocytosis, Ferroptosis, Glycosaminoglycan degradation, HIF-1 signaling pathway, Hematopoietic cell lineage, Lysosome, Metabolic pathways, Phagosome 💬1件: 19 💬