Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. KEGG DRUG DrugBank 薬物名（臨床試験情報から抽出） KEGG GENES KEGG PATHWAY 指定難病告示番号
1 Abatacept 💬1件: Abatacept1件: Abatacept2件: CD80,
CD86 💬 		13件: Allograft rejection, Autoimmune thyroid disease, Cell adhesion molecules, Graft-versus-host disease, Intestinal immune network for IgA production, Kaposi sarcoma-associated herpesvirus infection, Rheumatoid arthritis, Systemic lupus erythematosus, Toll-like receptor signaling pathway, Transcriptional misregulation in cancer, Type I diabetes mellitus, Viral myocarditis, Virion - Adenovirus 💬26件: 2, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
2 Acetaminophen 💬1件: Acetaminophen2件: Acetaminophen; Paracetamol2件: PTGS1,
PTGS2 💬 		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Efferocytosis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬17件: 3, 6, 11, 13, 19, 34, 46, 49, 51, 70, 77, 86, 96, 222, 256, 300, 337 💬
3 Adalimumab 💬1件: Adalimumab1件: Adalimumab1件: TNF 💬 66件: AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬18件: 19, 37, 40, 41, 46, 55, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
4 Afegostat 💬1件: Afegostat1件: Afegostat tartrate--1件: 19 💬
5 Afegostat tartrate 💬1件: Afegostat1件: Afegostat tartrate--1件: 19 💬
6 Agalsidase alfa 💬1件: Agalsidase alfa3件: Agalsidase alfa; Agalsidase alpha; Recombinant alpha-galactosidase A1件: GLA 💬 5件: Galactose metabolism, Glycerolipid metabolism, Glycosphingolipid biosynthesis - globo and isoglobo series, Lysosome, Sphingolipid metabolism 💬1件: 19 💬
7 Agalsidase beta 💬1件: Agalsidase beta1件: Agalsidase beta1件: GLA 💬 5件: Galactose metabolism, Glycerolipid metabolism, Glycosphingolipid biosynthesis - globo and isoglobo series, Lysosome, Sphingolipid metabolism 💬1件: 19 💬
8 Alemtuzumab 💬1件: Alemtuzumab1件: Alemtuzumab--18件: 13, 15, 19, 20, 36, 43, 44, 46, 51, 60, 65, 85, 96, 107, 283, 284, 285, 326 💬
9 Alendronate sodium 💬1件: Alendronic acid3件: Alendronate; Alendronate sodium; Alendronic acid1件: FDPS 💬 3件: Human T-cell leukemia virus 1 infection, Influenza A, Terpenoid backbone biosynthesis 💬7件: 19, 41, 46, 50, 271, 274, 299 💬
10 Alendronic acid 💬1件: Alendronic acid3件: Alendronate; Alendronate sodium; Alendronic acid1件: FDPS 💬 3件: Human T-cell leukemia virus 1 infection, Influenza A, Terpenoid backbone biosynthesis 💬7件: 19, 41, 46, 50, 271, 274, 299 💬
11 Alglucerase 💬1件: Imiglucerase2件: Imiglucerasa; Imiglucerase1件: GBA 💬 4件: Cornified envelope formation, Lysosome, Other glycan degradation, Sphingolipid metabolism 💬1件: 19 💬
12 Ambroxol 💬1件: Ambroxol2件: Ambroxol; Ambroxol hydrochloride--3件: 2, 6, 19 💬
13 Ambroxol hydrochloride 💬1件: Ambroxol2件: Ambroxol; Ambroxol hydrochloride--3件: 2, 6, 19 💬
14 Amoxicillin 💬1件: Amoxicillin2件: Amoxicilina; Amoxicillin--5件: 46, 63, 96, 97, 299 💬
15 Amoxicillin 💬1件: Amoxicillin2件: Amoxicilina; Amoxicillin--5件: 46, 63, 96, 97, 299 💬
16 Amoxicillin sodium 💬1件: Amoxicillin2件: Amoxicilina; Amoxicillin--5件: 46, 63, 96, 97, 299 💬
17 Anakinra 💬1件: Anakinra1件: Anakinra2件: IL1R1,
IL1R2 💬 		15件: Amoebiasis, Cytokine-cytokine receptor interaction, Fluid shear stress and atherosclerosis, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Inflammatory mediator regulation of TRP channels, MAPK signaling pathway, NF-kappa B signaling pathway, Osteoclast differentiation, Pathogenic Escherichia coli infection, Prostate cancer, Shigellosis, Th17 cell differentiation, Transcriptional misregulation in cancer 💬19件: 2, 13, 15, 19, 28, 37, 41, 46, 49, 50, 54, 56, 84, 86, 97, 106, 107, 266, 299 💬
18 Arimoclomol 💬1件: Arimoclomol2件: Arimoclomol; Arimoclomol citrate--3件: 2, 15, 19 💬
19 Arimoclomol citrate 💬1件: Arimoclomol2件: Arimoclomol; Arimoclomol citrate--3件: 2, 15, 19 💬
20 Ataluren 💬1件: Ataluren1件: Ataluren--6件: 19, 113, 140, 246, 299, 329 💬
21 Azathioprine 💬1件: Azathioprine2件: Azathioprine; Azatioprina--22件: 6, 11, 13, 19, 35, 42, 43, 44, 45, 46, 49, 55, 63, 65, 66, 84, 85, 94, 95, 96, 97, 162 💬
22 Azathioprine sodium 💬1件: Azathioprine2件: Azathioprine; Azatioprina--22件: 6, 11, 13, 19, 35, 42, 43, 44, 45, 46, 49, 55, 63, 65, 66, 84, 85, 94, 95, 96, 97, 162 💬
23 Busulfan 💬1件: Busulfan2件: Busulfan; Busulfano--14件: 19, 20, 28, 34, 36, 49, 51, 60, 65, 164, 274, 284, 285, 326 💬
24 Calcium carbonate 💬1件: Calcium carbonate1件: Calcium carbonate--7件: 13, 19, 46, 75, 96, 235, 299 💬
25 Calcium carbonate 💬1件: Calcium carbonate1件: Calcium carbonate--7件: 13, 19, 46, 75, 96, 235, 299 💬
26 Cannabidiol 💬1件: Cannabidiol1件: Cannabidiol2件: CNR1,
CNR2 💬 		4件: Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬18件: 6, 8, 13, 19, 36, 46, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 271 💬
27 Cannabis 💬1件: Medical Cannabis2件: Cannabis; Medical cannabis--6件: 6, 13, 46, 90, 96, 97 💬
28 Cerliponase alfa 💬1件: Cerliponase alfa2件: Cerliponase alfa; Recombinant human tripeptidyl peptidase-11件: TPP1 💬 1件: Lysosome 💬1件: 19 💬
29 Cetirizine 💬1件: Cetirizine3件: Cetirizina; Cetirizine; Cetirizine hydrochloride1件: HRH1 💬 4件: Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction 💬5件: 13, 19, 35, 300, 309 💬
30 Cetirizine hydrochloride 💬1件: Cetirizine3件: Cetirizina; Cetirizine; Cetirizine hydrochloride1件: HRH1 💬 4件: Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction 💬5件: 13, 19, 35, 300, 309 💬
31 Cholecalciferol 💬1件: Cholecalciferol4件: Cholecalciferol; Colecalciferol; Vitamin D-3; Vitamin D31件: VDR 💬 5件: Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬15件: 6, 13, 19, 20, 34, 46, 49, 51, 53, 65, 96, 97, 228, 298, 299 💬
32 Cholesterol 💬1件: Cholesterol1件: Cholesterol--5件: 19, 90, 160, 222, 310 💬
33 Clofarabine 💬1件: Clofarabine1件: Clofarabine3件: POLA1,
POLA2,
RRM1 💬 		5件: DNA replication, Drug metabolism - other enzymes, Glutathione metabolism, Purine metabolism, Pyrimidine metabolism 💬5件: 19, 20, 60, 96, 234 💬
34 Cyclophosphamide 💬1件: Cyclophosphamide5件: Ciclofosfamida; Ciclofosfamide; Cyclophosphamid; Cyclophosphamide; Cyclophosphamide monohydrate--46件: 11, 13, 14, 16, 19, 20, 26, 28, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 56, 60, 62, 65, 66, 84, 93, 96, 162, 164, 172, 205, 220, 221, 222, 224, 256, 265, 274, 283, 284, 285, 288, 326, 331 💬
35 Cyclophosphamide 💬1件: Cyclophosphamide5件: Ciclofosfamida; Ciclofosfamide; Cyclophosphamid; Cyclophosphamide; Cyclophosphamide monohydrate--46件: 11, 13, 14, 16, 19, 20, 26, 28, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 56, 60, 62, 65, 66, 84, 93, 96, 162, 164, 172, 205, 220, 221, 222, 224, 256, 265, 274, 283, 284, 285, 288, 326, 331 💬
36 Cyclosporine 💬1件: Cyclosporine6件: Ciclosporin; Ciclosporina; Ciclosporine; Cyclosporin; Cyclosporin A; Cyclosporine5件: PPP3C,
PPP3C,
PPP3C,
PPP3R,
PPP3R 💬 		33件: Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬37件: 11, 26, 28, 40, 41, 42, 45, 46, 49, 50, 53, 54, 55, 56, 60, 61, 62, 63, 64, 65, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 269, 274, 283, 284, 285, 302, 326 💬
37 Cysteamine 💬1件: Cysteamine6件: 2-aminoethanethiol; Cysteamine; Cysteamine bitartrate; Cysteamine hydrochloride; Mercaptamina; Mercaptamine--4件: 8, 19, 21, 299 💬
38 Cysteamine bitartrate 💬1件: Cysteamine6件: 2-aminoethanethiol; Cysteamine; Cysteamine bitartrate; Cysteamine hydrochloride; Mercaptamina; Mercaptamine--4件: 8, 19, 21, 299 💬
39 Cysteamine hydrochloride 💬1件: Cysteamine6件: 2-aminoethanethiol; Cysteamine; Cysteamine bitartrate; Cysteamine hydrochloride; Mercaptamina; Mercaptamine--4件: 8, 19, 21, 299 💬
40 Dapagliflozin 💬1件: Dapagliflozin1件: Dapagliflozin--10件: 6, 28, 49, 66, 67, 86, 88, 215, 218, 222 💬
41 Dexamethasone 💬1件: Dexamethasone2件: Dexamethasone; Dexamethasone sodium phosphate1件: NR3C1 💬 1件: Neuroactive ligand-receptor interaction 💬23件: 13, 14, 16, 19, 28, 35, 63, 64, 65, 70, 74, 75, 81, 84, 90, 96, 97, 222, 235, 257, 296, 299, 331 💬
42 Dexamethasone phosphate 💬1件: Dexamethasone2件: Dexamethasone; Dexamethasone sodium phosphate1件: NR3C1 💬 1件: Neuroactive ligand-receptor interaction 💬23件: 13, 14, 16, 19, 28, 35, 63, 64, 65, 70, 74, 75, 81, 84, 90, 96, 97, 222, 235, 257, 296, 299, 331 💬
43 Dexamethasone sodium phosphate 💬1件: Dexamethasone2件: Dexamethasone; Dexamethasone sodium phosphate1件: NR3C1 💬 1件: Neuroactive ligand-receptor interaction 💬23件: 13, 14, 16, 19, 28, 35, 63, 64, 65, 70, 74, 75, 81, 84, 90, 96, 97, 222, 235, 257, 296, 299, 331 💬
44 Diphenhydramine 💬1件: Diphenhydramine2件: Diphenhydramine; Diphenhydramine hydrochloride1件: HRH1 💬 4件: Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction 💬11件: 11, 13, 19, 49, 51, 70, 86, 96, 222, 256, 300 💬
45 Diphenhydramine citrate 💬1件: Diphenhydramine2件: Diphenhydramine; Diphenhydramine hydrochloride1件: HRH1 💬 4件: Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction 💬11件: 11, 13, 19, 49, 51, 70, 86, 96, 222, 256, 300 💬
46 Diphenhydramine hydrochloride 💬1件: Diphenhydramine2件: Diphenhydramine; Diphenhydramine hydrochloride1件: HRH1 💬 4件: Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction 💬11件: 11, 13, 19, 49, 51, 70, 86, 96, 222, 256, 300 💬
47 Diphenhydramine salicylate 💬1件: Diphenhydramine2件: Diphenhydramine; Diphenhydramine hydrochloride1件: HRH1 💬 4件: Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction 💬11件: 11, 13, 19, 49, 51, 70, 86, 96, 222, 256, 300 💬
48 Donkey glue 💬1件: Gelatin2件: Gelatin; Gelatine--5件: 19, 47, 62, 70, 296 💬
49 Edotreotide gallium Ga-68 💬1件: Dotatate gallium Ga-681件: 68GA-dotatate1件: SSTR2 💬 5件: Gastric acid secretion, Growth hormone synthesis, secretion and action, Hormone signaling, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬1件: 75 💬
50 Eliglustat 💬1件: Eliglustat2件: Eliglustat; Eliglustat tartrate1件: UGCG 💬 2件: Cornified envelope formation, Sphingolipid metabolism 💬1件: 19 💬
51 Eliglustat tartrate 💬1件: Eliglustat2件: Eliglustat; Eliglustat tartrate1件: UGCG 💬 2件: Cornified envelope formation, Sphingolipid metabolism 💬1件: 19 💬
52 Elosulfase alfa 💬1件: Elosulfase alfa2件: Elosulfase alfa; Rhgalns1件: GALNS 💬 2件: Glycosaminoglycan degradation, Lysosome 💬1件: 19 💬
53 Enalapril 💬1件: Enalapril2件: Enalapril; Enalapril maleate1件: ACE 💬 6件: Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬7件: 13, 46, 66, 113, 210, 222, 279 💬
54 Enalapril maleate 💬1件: Enalapril2件: Enalapril; Enalapril maleate1件: ACE 💬 6件: Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬7件: 13, 46, 66, 113, 210, 222, 279 💬
55 Fexofenadine 💬1件: Fexofenadine1件: Fexofenadine1件: HRH1 💬 4件: Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction 💬4件: 6, 13, 19, 46 💬
56 Fexofenadine hydrochloride 💬1件: Fexofenadine1件: Fexofenadine1件: HRH1 💬 4件: Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction 💬4件: 6, 13, 19, 46 💬
57 Fludarabine 💬1件: Fludarabine2件: Fludarabine; Fludarabine phosphate1件: RRM1 💬 4件: Drug metabolism - other enzymes, Glutathione metabolism, Purine metabolism, Pyrimidine metabolism 💬25件: 11, 13, 19, 28, 34, 35, 36, 44, 46, 49, 51, 60, 61, 62, 65, 85, 96, 107, 164, 222, 283, 284, 285, 286, 326 💬
58 Fludarabine phosphate 💬1件: Fludarabine2件: Fludarabine; Fludarabine phosphate1件: RRM1 💬 4件: Drug metabolism - other enzymes, Glutathione metabolism, Purine metabolism, Pyrimidine metabolism 💬25件: 11, 13, 19, 28, 34, 35, 36, 44, 46, 49, 51, 60, 61, 62, 65, 85, 96, 107, 164, 222, 283, 284, 285, 286, 326 💬
59 Fluorescein 💬1件: Fluorescein1件: Fluorescein--2件: 22, 97 💬
60 Fluorescein sodium 💬1件: Fluorescein1件: Fluorescein--2件: 22, 97 💬
61 Folinic acid 💬1件: Leucovorin2件: Folinic acid; Leucovorin--3件: 19, 46, 320 💬
62 Folinic acid calcium salt pentahydrate 💬1件: Leucovorin2件: Folinic acid; Leucovorin--3件: 19, 46, 320 💬
63 Gabapentin 💬1件: Gabapentin2件: Gabapentin; Gabapentine5件: CACNA2D1,
CACNA2D2,
CACNA2D3,
CACNA2D4,
SLC6A1 💬 		10件: Adrenergic signaling in cardiomyocytes, Arrhythmogenic right ventricular cardiomyopathy, Cardiac muscle contraction, Dilated cardiomyopathy, GABAergic synapse, Hypertrophic cardiomyopathy, MAPK signaling pathway, Neuroactive ligand signaling, Oxytocin signaling pathway, Synaptic vesicle cycle 💬4件: 6, 13, 19, 70 💬
64 Galsulfase 💬1件: Galsulfase1件: Galsulfase1件: ARSB 💬 2件: Glycosaminoglycan degradation, Lysosome 💬1件: 19 💬
65 Gamolenic acid 💬1件: Gamolenic acid1件: Gamma-linolenic acid--1件: 46 💬
66 Gelatin 💬1件: Gelatin2件: Gelatin; Gelatine--5件: 19, 47, 62, 70, 296 💬
67 Genistein 💬1件: Genistein1件: Genistein--1件: 299 💬
68 Hydroxyurea 💬1件: Hydroxyurea1件: Hydroxyurea1件: RRM2 💬 5件: Drug metabolism - other enzymes, Glutathione metabolism, Purine metabolism, Pyrimidine metabolism, p53 signaling pathway 💬10件: 3, 13, 19, 20, 46, 65, 85, 86, 107, 284 💬
69 Idursulfase 💬1件: Idursulfase2件: Idursulfasa; Idursulfase1件: IDS 💬 2件: Glycosaminoglycan degradation, Lysosome 💬1件: 19 💬
70 Idursulfase beta 💬1件: Idursulfase beta2件: Hunterase; Idursulfase beta1件: IDS 💬 2件: Glycosaminoglycan degradation, Lysosome 💬1件: 19 💬
71 Imiglucerase 💬1件: Imiglucerase2件: Imiglucerasa; Imiglucerase1件: GBA 💬 4件: Cornified envelope formation, Lysosome, Other glycan degradation, Sphingolipid metabolism 💬1件: 19 💬
72 Iohexol 💬1件: Iohexol1件: Iohexol--2件: 19, 67 💬
73 Laronidase 💬1件: Laronidase1件: Laronidase1件: IDUA 💬 2件: Glycosaminoglycan degradation, Lysosome 💬2件: 19, 256 💬
74 Ledipasvir 💬1件: Ledipasvir0件: ---
75 Lenograstim 💬1件: Lenograstim2件: G-CSF; Lenograstim1件: CSF3R 💬 5件: Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer 💬8件: 2, 13, 16, 18, 19, 57, 65, 97 💬
76 Lesinidase alfa 💬1件: Lesinidase alfa1件: SBC-1031件: NAGLU 💬 2件: Glycosaminoglycan degradation, Lysosome 💬1件: 19 💬
77 Leucovorin calcium 💬1件: Leucovorin2件: Folinic acid; Leucovorin--3件: 19, 46, 320 💬
78 Lisinopril 💬1件: Lisinopril1件: Lisinopril1件: ACE 💬 6件: Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬5件: 19, 46, 66, 67, 113 💬
79 Lisinopril 💬1件: Lisinopril1件: Lisinopril1件: ACE 💬 6件: Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬5件: 19, 46, 66, 67, 113 💬
80 Loratadine 💬1件: Loratadine1件: Loratadine1件: HRH1 💬 4件: Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction 💬5件: 13, 19, 46, 89, 98 💬
81 Losartan 💬1件: Losartan2件: Losartan; Losartan potassium1件: AGTR1 💬 17件: AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Hormone signaling, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
82 Losartan potassium 💬1件: Losartan2件: Losartan; Losartan potassium1件: AGTR1 💬 17件: AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Hormone signaling, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
83 Lucerastat 💬1件: Lucerastat1件: Lucerastat1件: UGCG 💬 2件: Cornified envelope formation, Sphingolipid metabolism 💬1件: 19 💬
84 Lysine 💬1件: Lysine1件: Lysine--1件: 228 💬
85 Lysine acetate 💬1件: Lysine1件: Lysine--1件: 228 💬
86 Lysine hydrochloride 💬1件: Lysine1件: Lysine--1件: 228 💬
87 Lysine hydrochloride 💬1件: Lysine1件: Lysine--1件: 228 💬
88 Melphalan 💬1件: Melphalan2件: Melphalan; Melphalan hydrochloride--19件: 11, 13, 14, 19, 20, 28, 34, 46, 60, 62, 65, 96, 107, 164, 222, 234, 284, 285, 299 💬
89 Melphalan hydrochloride 💬1件: Melphalan2件: Melphalan; Melphalan hydrochloride--19件: 11, 13, 14, 19, 20, 28, 34, 46, 60, 62, 65, 96, 107, 164, 222, 234, 284, 285, 299 💬
90 Methotrexate 💬1件: Methotrexate5件: Methotrexat; Methotrexate; Methotrexate sodium; Metotrexato; Méthotrexate2件: DHFR,
DHFR 💬 		3件: Folate biosynthesis, Folate transport and metabolism, One carbon pool by folate 💬37件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 54, 55, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 284, 285, 286, 326, 331 💬
91 Methotrexate sodium 💬1件: Methotrexate5件: Methotrexat; Methotrexate; Methotrexate sodium; Metotrexato; Méthotrexate2件: DHFR,
DHFR 💬 		3件: Folate biosynthesis, Folate transport and metabolism, One carbon pool by folate 💬37件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 54, 55, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 284, 285, 286, 326, 331 💬
92 Methylprednisolone 💬1件: Methylprednisolone3件: Methylprednisolon; Methylprednisolone; Methylprednisolone acetate1件: NR3C1 💬 1件: Neuroactive ligand-receptor interaction 💬45件: 2, 6, 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 96, 97, 127, 162, 164, 222, 224, 271, 283, 284, 285, 296, 300 💬
93 Methylprednisolone acetate 💬1件: Methylprednisolone3件: Methylprednisolon; Methylprednisolone; Methylprednisolone acetate1件: NR3C1 💬 1件: Neuroactive ligand-receptor interaction 💬45件: 2, 6, 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 96, 97, 127, 162, 164, 222, 224, 271, 283, 284, 285, 296, 300 💬
94 Migalastat 💬1件: Migalastat2件: Migalastat; Migalastat hydrochloride--1件: 19 💬
95 Migalastat hydrochloride 💬1件: Migalastat2件: Migalastat; Migalastat hydrochloride1件: GLA 💬 5件: Galactose metabolism, Glycerolipid metabolism, Glycosphingolipid biosynthesis - globo and isoglobo series, Lysosome, Sphingolipid metabolism 💬1件: 19 💬
96 Miglustat 💬1件: Miglustat2件: AT2221; Miglustat1件: UGCG 💬 2件: Cornified envelope formation, Sphingolipid metabolism 💬3件: 19, 256, 299 💬
97 Montelukast 💬1件: Montelukast2件: Montelukast; Montelukast sodium1件: CYSLTR1 💬 2件: Calcium signaling pathway, Neuroactive ligand-receptor interaction 💬9件: 6, 13, 19, 46, 61, 63, 85, 98, 228 💬
98 Montelukast sodium 💬1件: Montelukast2件: Montelukast; Montelukast sodium1件: CYSLTR1 💬 2件: Calcium signaling pathway, Neuroactive ligand-receptor interaction 💬9件: 6, 13, 19, 46, 61, 63, 85, 98, 228 💬
99 Mycophenolate mofetil 💬1件: Mycophenolate mofetil1件: Mycophenolate mofetil2件: IMPDH,
IMPDH 💬 		2件: Drug metabolism - other enzymes, Purine metabolism 💬32件: 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 46, 49, 51, 53, 60, 62, 63, 65, 66, 93, 95, 96, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬
100 Mycophenolate mofetil hydrochloride 💬1件: Mycophenolate mofetil1件: Mycophenolate mofetil2件: IMPDH,
IMPDH 💬 		2件: Drug metabolism - other enzymes, Purine metabolism 💬32件: 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 46, 49, 51, 53, 60, 62, 63, 65, 66, 93, 95, 96, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬
101 Mycophenolate sodium 💬1件: Mycophenolic acid5件: Acido micofenolico; Micofenolico acido; Mycophenolate; Mycophenolate sodium; Mycophenolic acid2件: IMPDH,
IMPDH 💬 		2件: Drug metabolism - other enzymes, Purine metabolism 💬12件: 11, 43, 49, 51, 53, 60, 66, 84, 96, 162, 222, 228 💬
102 Mycophenolic acid 💬1件: Mycophenolic acid5件: Acido micofenolico; Micofenolico acido; Mycophenolate; Mycophenolate sodium; Mycophenolic acid2件: IMPDH,
IMPDH 💬 		2件: Drug metabolism - other enzymes, Purine metabolism 💬12件: 11, 43, 49, 51, 53, 60, 66, 84, 96, 162, 222, 228 💬
103 Olipudase alfa 💬1件: Olipudase alfa1件: Olipudase alfa1件: SMPD1 💬 4件: Lysosome, Necroptosis, Sphingolipid metabolism, Sphingolipid signaling pathway 💬1件: 19 💬
104 Oxygen 💬1件: Oxygen1件: Oxygen--13件: 22, 49, 70, 85, 86, 88, 149, 168, 235, 271, 298, 299, 330 💬
105 Pabinafusp alfa 💬1件: Pabinafusp alfa1件: Pabinafusp alfa2件: IDS,
TFRC 💬 		9件: Endocytosis, Ferroptosis, Glycosaminoglycan degradation, HIF-1 signaling pathway, Hematopoietic cell lineage, Lysosome, Phagosome, TGF-beta signaling pathway, Virion - Lassa virus and SFTS virus 💬1件: 19 💬
106 Paricalcitol 💬1件: Paricalcitol1件: Paricalcitol1件: VDR 💬 5件: Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬5件: 19, 66, 218, 238, 298 💬
107 Pegunigalsidase alfa 💬1件: Pegunigalsidase alfa1件: Pegunigalsidase alfa1件: GLA 💬 5件: Galactose metabolism, Glycerolipid metabolism, Glycosphingolipid biosynthesis - globo and isoglobo series, Lysosome, Sphingolipid metabolism 💬1件: 19 💬
108 Pentosan polysulfate sodium 💬1件: Pentosan polysulfate2件: Pentosan polysulfate; Pentosan polysulfate sodium--2件: 19, 26 💬
109 Prednisone 💬1件: Prednisone2件: Prednisona; Prednisone1件: NR3C1 💬 1件: Neuroactive ligand-receptor interaction 💬54件: 2, 11, 13, 14, 18, 19, 26, 28, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 60, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 90, 93, 95, 96, 97, 113, 145, 162, 164, 205, 222, 224, 228, 251, 269, 283, 285, 288, 299, 300, 303, 307, 331 💬
110 Pyrimethamine 💬1件: Pyrimethamine1件: Pyrimethamine--4件: 2, 4, 19, 65 💬
111 Rimiducid 💬1件: Rimiducid1件: Rimiducid1件: CASP9 💬 34件: Alzheimer disease, Amyotrophic lateral sclerosis, Apoptosis, Apoptosis - multiple species, Colorectal cancer, Endometrial cancer, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Huntington disease, Influenza A, Kaposi sarcoma-associated herpesvirus infection, Legionellosis, Lipid and atherosclerosis, Measles, Non-small cell lung cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Parkinson disease, Pathogenic Escherichia coli infection, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Prostate cancer, Small cell lung cancer, Thyroid hormone signaling pathway, Toxoplasmosis, Tuberculosis, VEGF signaling pathway, Viral myocarditis, p53 signaling pathway 💬7件: 19, 49, 60, 65, 284, 285, 326 💬
112 Rituximab 💬1件: Rituximab1件: Rituximab1件: MS4A1 💬 1件: Hematopoietic cell lineage 💬52件: 11, 13, 14, 19, 26, 34, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 55, 56, 60, 61, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 162, 172, 220, 222, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331 💬
113 Rivogenlecleucel 💬1件: Rivogenlecleucel1件: Rivogenlecleucel--6件: 19, 60, 65, 284, 285, 326 💬
114 Sebelipase alfa 💬1件: Sebelipase alfa2件: SBC-102; Sebelipase alfa1件: LIPA 💬 4件: Cholesterol metabolism, Efferocytosis, Lysosome, Steroid biosynthesis 💬1件: 19 💬
115 Sirolimus 💬1件: Sirolimus2件: Rapamycin; Sirolimus1件: MTOR 💬 49件: AMPK signaling pathway, Acute myeloid leukemia, Adipocytokine signaling pathway, Alzheimer disease, Amyotrophic lateral sclerosis, Apelin signaling pathway, Autophagy - animal, Autophagy - other, Breast cancer, Cellular senescence, Central carbon metabolism in cancer, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Diabetic cardiomyopathy, ErbB signaling pathway, Gastric cancer, Glioma, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatocellular carcinoma, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Huntington disease, Insulin resistance, Insulin signaling pathway, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Longevity regulating pathway, Longevity regulating pathway - multiple species, MicroRNAs in cancer, Neutrophil extracellular trap formation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Shigellosis, Spinocerebellar ataxia, Th17 cell differentiation, Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus, mTOR signaling pathway 💬44件: 2, 6, 13, 15, 19, 21, 34, 35, 36, 46, 48, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 97, 98, 137, 157, 158, 192, 193, 222, 227, 256, 277, 278, 279, 280, 281, 283, 285, 300, 331 💬
116 Somatropin 💬1件: Somatotropin7件: Growth hormone; Human growth hormone; Recombinant human growth hormone; Rhgh; Somatotropin; Somatropin; Somatropina1件: GHR 💬 6件: Cytokine-cytokine receptor interaction, Growth hormone synthesis, secretion and action, Hormone signaling, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway 💬26件: 2, 3, 19, 46, 65, 74, 75, 76, 77, 78, 96, 97, 107, 113, 156, 187, 191, 193, 195, 238, 246, 265, 274, 276, 299, 337 💬
117 Taliglucerase alfa 💬1件: Taliglucerase alfa2件: Prgcd; Taliglucerase alfa1件: GBA 💬 4件: Cornified envelope formation, Lysosome, Other glycan degradation, Sphingolipid metabolism 💬1件: 19 💬
118 Thiotepa 💬1件: Thiotepa1件: Thiotepa--11件: 13, 28, 46, 51, 60, 65, 85, 96, 107, 284, 285 💬
119 Tividenofusp alfa 💬1件: Tividenofusp alfa1件: Tividenofusp alfa2件: IDS,
TFRC 💬 		9件: Endocytosis, Ferroptosis, Glycosaminoglycan degradation, HIF-1 signaling pathway, Hematopoietic cell lineage, Lysosome, Phagosome, TGF-beta signaling pathway, Virion - Lassa virus and SFTS virus 💬1件: 19 💬
120 Treosulfan 💬1件: Treosulfan1件: Treosulfan--6件: 13, 19, 62, 65, 284, 286 💬
121 Tropicamide 💬1件: Tropicamide1件: Tropicamide5件: CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5 💬 		14件: Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬1件: 19 💬
122 Velaglucerase alfa 💬1件: Velaglucerase alfa2件: GA-GCB; Velaglucerase alfa1件: GBA 💬 4件: Cornified envelope formation, Lysosome, Other glycan degradation, Sphingolipid metabolism 💬1件: 19 💬
123 Velmanase alfa 💬1件: Velmanase alfa3件: Lamazym; Rhlaman; Velmanase alfa1件: MAN2B1 💬 2件: Lysosome, Other glycan degradation 💬1件: 19 💬
124 Venglustat 💬1件: Venglustat2件: Venglustat; Venglustat malate1件: UGCG 💬 2件: Cornified envelope formation, Sphingolipid metabolism 💬3件: 6, 19, 67 💬
125 Venglustat malate 💬1件: Venglustat2件: Venglustat; Venglustat malate--3件: 6, 19, 67 💬
126 Vestronidase alfa 💬1件: Vestronidase alfa2件: Recombinant human BETA-glucuronidase; Vestronidase alfa1件: uidA 💬 6件: Ascorbate and aldarate metabolism, Drug metabolism - other enzymes, Glycosaminoglycan degradation, Lysosome, Pentose and glucuronate interconversions, Porphyrin metabolism 💬1件: 19 💬
127 Vitamin E 💬1件: Vitamin E2件: Alpha-tocopherol; Vitamin E--6件: 2, 19, 20, 49, 90, 206 💬
128 Vosoritide 💬1件: Vosoritide1件: Vosoritide1件: NPR2 💬 5件: Hormone signaling, Oxytocin signaling pathway, Purine metabolism, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬2件: 19, 276 💬
129 Warfarin 💬1件: Warfarin3件: Warfarin; Warfarin potassium; Warfarin sodium2件: NQO1,
VKORC1 💬 		5件: Chemical carcinogenesis - reactive oxygen species, Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Pathways in cancer, Ubiquinone and other terpenoid-quinone biosynthesis 💬10件: 6, 8, 19, 46, 49, 66, 85, 86, 88, 91 💬
130 Warfarin potassium 💬1件: Warfarin3件: Warfarin; Warfarin potassium; Warfarin sodium2件: NQO1,
VKORC1 💬 		5件: Chemical carcinogenesis - reactive oxygen species, Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Pathways in cancer, Ubiquinone and other terpenoid-quinone biosynthesis 💬10件: 6, 8, 19, 46, 49, 66, 85, 86, 88, 91 💬
131 Warfarin sodium 💬1件: Warfarin3件: Warfarin; Warfarin potassium; Warfarin sodium2件: NQO1,
VKORC1 💬 		5件: Chemical carcinogenesis - reactive oxygen species, Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Pathways in cancer, Ubiquinone and other terpenoid-quinone biosynthesis 💬10件: 6, 8, 19, 46, 49, 66, 85, 86, 88, 91 💬
132 Water 💬1件: Water1件: Water--25件: 2, 5, 6, 13, 17, 19, 22, 46, 51, 53, 56, 57, 63, 64, 66, 67, 85, 96, 97, 206, 226, 230, 274, 278, 299 💬