Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank 薬物名（臨床試験情報から抽出） KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
1 4D-310 1件: 4D-310---1件: 19 💬
2 Abatacept 1件: Abatacept1件: Abatacept 💬 2件: CD80,
CD86 💬 		14件: Allograft rejection, Autoimmune thyroid disease, Cell adhesion molecule (CAM) interaction, Graft-versus-host disease, IgSF CAM signaling, Intestinal immune network for IgA production, Kaposi sarcoma-associated herpesvirus infection, Rheumatoid arthritis, Systemic lupus erythematosus, Toll-like receptor signaling pathway, Transcriptional misregulation in cancer, Type I diabetes mellitus, Viral myocarditis, Virion - Adenovirus 💬28件: 2, 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 223, 271, 284, 285, 300 💬
3 Acetaminophen 2件: Acetaminophen; Paracetamol1件: Acetaminophen 💬 2件: PTGS1,
PTGS2 💬 		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Efferocytosis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬19件: 11, 13, 19, 34, 35, 46, 49, 51, 63, 70, 77, 86, 96, 222, 231, 256, 271, 300, 337 💬
4 Acetylcysteine 4件: Acetylcysteine; N acetyl cysteine; N-acetyl Cysteine; N-acetylcysteine1件: Acetylcysteine 💬 --25件: 2, 6, 13, 19, 20, 21, 34, 49, 51, 53, 58, 63, 85, 90, 94, 97, 111, 164, 193, 233, 296, 298, 299, 303, 337 💬
5 Acetylcysteine amide 2件: Acetylcysteine amide; N-acetylcysteine amide---3件: 19, 90, 303 💬
6 Adalimumab 1件: Adalimumab1件: Adalimumab 💬 1件: TNF 💬 66件: AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬22件: 19, 37, 38, 40, 41, 46, 55, 56, 84, 90, 96, 97, 107, 151, 160, 162, 164, 222, 226, 269, 270, 271 💬
7 Afegostat 2件: Afegostat; Afegostat tartrate2件: Afegostat ,
Afegostat tartrate 💬 		--1件: 19 💬
8 Agalsidase alfa 3件: AGALSIDASE ALFA; Agalsidase Alpha; Recombinant alpha-galactosidase A1件: Agalsidase alfa 💬 1件: GLA 💬 5件: Galactose metabolism, Glycerolipid metabolism, Glycosphingolipid biosynthesis - globo and isoglobo series, Lysosome biogenesis, Sphingolipid metabolism 💬1件: 19 💬
9 Agalsidase beta 1件: AGALSIDASE BETA1件: Agalsidase beta 💬 1件: GLA 💬 5件: Galactose metabolism, Glycerolipid metabolism, Glycosphingolipid biosynthesis - globo and isoglobo series, Lysosome biogenesis, Sphingolipid metabolism 💬1件: 19 💬
10 AGT-182 1件: AGT-182---1件: 19 💬
11 AL-01211 0件: ---2件: 19, 67 💬
12 Alemtuzumab 1件: Alemtuzumab1件: Alemtuzumab 💬 --21件: 13, 14, 15, 19, 20, 36, 43, 44, 46, 51, 60, 63, 65, 85, 96, 107, 164, 283, 284, 285, 326 💬
13 Alendronic acid 3件: Alendronate; Alendronate sodium; Alendronic acid2件: Alendronate sodium ,
Alendronic acid 💬 		1件: FDPS 💬 3件: Human T-cell leukemia virus 1 infection, Influenza A, Terpenoid backbone biosynthesis 💬5件: 19, 46, 223, 274, 299 💬
14 Ambroxol 2件: Ambroxol; AMBROXOL HYDROCHLORIDE2件: Ambroxol hydrochloride ,
Ambroxol 💬 		--3件: 2, 6, 19 💬
15 Anakinra 1件: Anakinra1件: Anakinra 💬 2件: IL1R1,
IL1R2 💬 		15件: Amoebiasis, Cytokine-cytokine receptor interaction, Fluid shear stress and atherosclerosis, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Inflammatory mediator regulation of TRP channels, MAPK signaling pathway, NF-kappa B signaling pathway, Osteoclast differentiation, Pathogenic Escherichia coli infection, Prostate cancer, Shigellosis, Th17 cell differentiation, Transcriptional misregulation in cancer 💬22件: 2, 13, 15, 19, 28, 37, 41, 46, 49, 50, 54, 56, 57, 84, 86, 97, 106, 107, 149, 153, 266, 299 💬
16 Arimoclomol 2件: ARIMOCLOMOL; Arimoclomol citrate2件: Arimoclomol ,
Arimoclomol citrate 💬 		--3件: 2, 15, 19 💬
17 Ataluren 1件: ATALUREN1件: Ataluren 💬 --6件: 19, 113, 140, 246, 299, 329 💬
18 AVR-RD-01 1件: AVR-RD-01---1件: 19 💬
19 AVR-RD-02 1件: AVR-RD-02---1件: 19 💬
20 Azathioprine 2件: Azathioprine; Azatioprina2件: Azathioprine ,
Azathioprine sodium 💬 		--26件: 6, 11, 13, 19, 35, 42, 43, 44, 45, 46, 49, 55, 57, 63, 65, 66, 84, 85, 93, 94, 95, 96, 97, 162, 223, 300 💬
21 Barium 1件: Barium---5件: 2, 6, 19, 97, 98 💬
22 Busulfan 2件: Busulfan; BUSULFANO1件: Busulfan 💬 --14件: 19, 20, 28, 34, 36, 49, 51, 60, 65, 164, 274, 284, 285, 326 💬
23 Calcium 1件: Calcium---39件: 2, 3, 6, 13, 15, 19, 46, 48, 49, 51, 53, 56, 62, 67, 68, 71, 74, 75, 79, 84, 90, 93, 94, 95, 96, 97, 156, 186, 214, 215, 222, 224, 235, 256, 265, 271, 274, 298, 299 💬
24 Calcium carbonate 1件: Calcium carbonate2件: Calcium carbonate ,
Calcium carbonate 💬 		--10件: 13, 19, 46, 53, 71, 75, 96, 97, 235, 299 💬
25 Cannabidiol 1件: CANNABIDIOL1件: Cannabidiol 💬 2件: CNR1,
CNR2 💬 		4件: Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬20件: 6, 8, 13, 19, 36, 46, 51, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271 💬
26 Capsaicin 1件: Capsaicin1件: Capsaicin 💬 1件: TRPV1 💬 2件: Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬5件: 2, 6, 19, 86, 226 💬
27 Cerliponase alfa 2件: Cerliponase Alfa; Recombinant human tripeptidyl peptidase-11件: Cerliponase alfa 💬 1件: TPP1 💬 1件: Lysosome biogenesis 💬1件: 19 💬
28 Cetirizine 3件: Cetirizina; Cetirizine; CETIRIZINE HYDROCHLORIDE2件: Cetirizine hydrochloride ,
Cetirizine 💬 		1件: HRH1 💬 4件: Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction 💬3件: 13, 19, 35 💬
29 Cholecalciferol 4件: Cholecalciferol; Colecalciferol; Vitamin D-3; Vitamin D31件: Cholecalciferol 💬 1件: VDR 💬 5件: Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬10件: 13, 19, 34, 46, 49, 96, 97, 222, 298, 299 💬
30 Cholesterol 1件: Cholesterol1件: Cholesterol 💬 --10件: 8, 19, 71, 79, 90, 160, 222, 259, 261, 310 💬
31 Clofarabine 1件: Clofarabine1件: Clofarabine 💬 3件: POLA1,
POLA2,
RRM1 💬 		5件: DNA replication, Drug metabolism - other enzymes, Glutathione metabolism, Purine metabolism, Pyrimidine metabolism 💬9件: 19, 20, 40, 46, 49, 60, 96, 234, 326 💬
32 Cyclophosphamide 5件: Ciclofosfamida; CICLOFOSFAMIDE; Cyclophosphamid; CYCLOPHOSPHAMIDE; CYCLOPHOSPHAMIDE MONOHYDRATE2件: Cyclophosphamide ,
Cyclophosphamide 💬 		--50件: 11, 13, 14, 16, 19, 20, 26, 28, 34, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 56, 60, 61, 62, 63, 65, 66, 84, 93, 96, 162, 164, 172, 205, 221, 222, 223, 224, 256, 265, 274, 283, 284, 285, 288, 326, 331 💬
33 Cyclosporine 7件: CICLOSPORIN; CICLOSPORINA; Ciclosporine; Cyclosporin; Cyclosporin A; Cyclosporine; Cyclosporine A1件: Cyclosporine 💬 5件: PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬 		33件: Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬39件: 11, 14, 19, 20, 28, 36, 40, 41, 42, 45, 46, 49, 50, 53, 56, 58, 60, 61, 62, 63, 64, 65, 67, 90, 95, 97, 107, 118, 162, 164, 222, 223, 226, 228, 234, 283, 284, 285, 302 💬
34 Cysteamine 6件: 2-aminoethanethiol; Cysteamine; Cysteamine Bitartrate; CYSTEAMINE HYDROCHLORIDE; Mercaptamina; Mercaptamine3件: Cysteamine ,
Cysteamine hydrochloride ,
Cysteamine bitartrate 💬 		--4件: 8, 19, 21, 299 💬
35 Cysteine 2件: Cysteine; Cysteine hydrochloride2件: L-Cysteine ,
Cysteine hydrochloride 💬 		--13件: 6, 13, 19, 34, 60, 84, 85, 88, 90, 254, 296, 310, 337 💬
36 Dapagliflozin 1件: Dapagliflozin1件: Dapagliflozin 💬 --16件: 6, 19, 28, 40, 41, 49, 57, 66, 67, 86, 88, 97, 210, 215, 218, 222 💬
37 Dexamethasone 4件: Dexametasone; Dexamethason; Dexamethasone; Dexamethasone sodium phosphate3件: Dexamethasone ,
Dexamethasone sodium phosphate ,
Dexamethasone phosphate 💬 		1件: NR3C1 💬 1件: Neuroactive ligand-receptor interaction 💬29件: 13, 14, 16, 19, 28, 35, 46, 53, 63, 64, 65, 70, 71, 74, 75, 81, 84, 90, 96, 97, 162, 222, 223, 235, 257, 283, 296, 299, 331 💬
38 Diphenhydramine 2件: Diphenhydramine; Diphenhydramine hydrochloride4件: Diphenhydramine ,
Diphenhydramine hydrochloride ,
Diphenhydramine salicylate ,
Diphenhydramine citrate 💬 		1件: HRH1 💬 4件: Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction 💬12件: 11, 13, 19, 49, 51, 63, 70, 86, 96, 222, 256, 300 💬
39 Dotatate 1件: Dotatate---5件: 19, 41, 75, 84, 238 💬
40 Eliglustat 2件: Eliglustat; ELIGLUSTAT TARTRATE2件: Eliglustat ,
Eliglustat tartrate 💬 		1件: UGCG 💬 2件: Cornified envelope formation, Sphingolipid metabolism 💬1件: 19 💬
41 Elosulfase alfa 1件: Elosulfase alfa1件: Elosulfase alfa 💬 1件: GALNS 💬 2件: Glycosaminoglycan degradation, Lysosome biogenesis 💬1件: 19 💬
42 ELX-02 1件: ELX-02---3件: 19, 218, 299 💬
43 Enalapril 2件: ENALAPRIL; Enalapril Maleate2件: Enalapril maleate ,
Enalapril 💬 		1件: ACE 💬 6件: Chagas disease, Coronavirus disease, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬10件: 13, 19, 46, 57, 66, 113, 210, 222, 223, 279 💬
44 FBX-101 1件: FBX-101---1件: 19 💬
45 Fexofenadine 1件: Fexofenadine2件: Fexofenadine hydrochloride ,
Fexofenadine 💬 		1件: HRH1 💬 4件: Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction 💬4件: 6, 13, 19, 46 💬
46 FLT190 1件: FLT190---1件: 19 💬
47 FLT201 1件: FLT201---1件: 19 💬
48 Fludarabine 3件: FLUDARABINA; Fludarabine; Fludarabine phosphate2件: Fludarabine phosphate ,
Fludarabine 💬 		1件: RRM1 💬 4件: Drug metabolism - other enzymes, Glutathione metabolism, Purine metabolism, Pyrimidine metabolism 💬30件: 11, 13, 14, 16, 19, 28, 34, 35, 36, 44, 46, 49, 50, 51, 60, 61, 62, 63, 65, 85, 96, 107, 164, 222, 223, 283, 284, 285, 286, 326 💬
49 Fluorescein 1件: Fluorescein2件: Fluorescein ,
Fluorescein sodium 💬 		--4件: 19, 22, 41, 97 💬
50 Gabapentin 3件: Gabapentin; GABAPENTINA; Gabapentine1件: Gabapentin 💬 5件: CACNA2D1,
CACNA2D2,
CACNA2D3,
CACNA2D4,
SLC6A1 💬 		10件: Adrenergic signaling in cardiomyocytes, Arrhythmogenic right ventricular cardiomyopathy, Cardiac muscle contraction, Dilated cardiomyopathy, GABAergic synapse, Hypertrophic cardiomyopathy, MAPK signaling pathway, Neuroactive ligand signaling, Oxytocin signaling pathway, Synaptic vesicle cycle 💬7件: 6, 13, 18, 19, 70, 226, 298 💬
51 Galsulfase 1件: GALSULFASE1件: Galsulfase 💬 1件: ARSB 💬 2件: Glycosaminoglycan degradation, Lysosome biogenesis 💬1件: 19 💬
52 Genistein 1件: GENISTEIN1件: Genistein 💬 --2件: 19, 299 💬
53 Gold 1件: Gold---71件: 2, 5, 6, 11, 13, 17, 19, 21, 22, 28, 34, 35, 46, 49, 50, 53, 54, 56, 57, 58, 60, 63, 64, 65, 66, 68, 71, 75, 76, 77, 79, 84, 85, 86, 88, 91, 93, 95, 96, 97, 98, 107, 113, 127, 137, 158, 162, 167, 171, 193, 206, 215, 218, 222, 223, 224, 226, 227, 228, 230, 235, 271, 291, 294, 296, 298, 299, 310, 318, 331, 340 💬
54 HMI-203 1件: HMI-203---1件: 19 💬
55 Hydroxyurea 1件: Hydroxyurea1件: Hydroxyurea 💬 1件: RRM2 💬 5件: Drug metabolism - other enzymes, Glutathione metabolism, Purine metabolism, Pyrimidine metabolism, p53 signaling pathway 💬10件: 3, 13, 19, 20, 46, 65, 85, 86, 107, 284 💬
56 Idursulfase 2件: IDURSULFASA; IDURSULFASE1件: Idursulfase 💬 1件: IDS 💬 2件: Glycosaminoglycan degradation, Lysosome biogenesis 💬1件: 19 💬
57 Idursulfase beta 2件: Hunterase; Idursulfase beta1件: Idursulfase beta 💬 1件: IDS 💬 2件: Glycosaminoglycan degradation, Lysosome biogenesis 💬1件: 19 💬
58 Imiglucerase 2件: IMIGLUCERASA; IMIGLUCERASE2件: Alglucerase ,
Imiglucerase 💬 		1件: GBA1 💬 4件: Cornified envelope formation, Lysosome biogenesis, Other glycan degradation, Sphingolipid metabolism 💬1件: 19 💬
59 Iohexol 1件: Iohexol1件: Iohexol 💬 --2件: 19, 67 💬
60 Isaralgagene civaparvovec 1件: Isaralgagene civaparvovec---1件: 19 💬
61 Laronidase 1件: LARONIDASE1件: Laronidase 💬 1件: IDUA 💬 2件: Glycosaminoglycan degradation, Lysosome biogenesis 💬2件: 19, 256 💬
62 Ledipasvir 1件: Ledipasvir1件: Ledipasvir 💬 --1件: 19 💬
63 Lenograstim 2件: G-CSF; Lenograstim1件: Lenograstim 💬 1件: CSF3R 💬 5件: Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer 💬8件: 2, 13, 16, 18, 19, 57, 65, 97 💬
64 Lepunafusp alfa 1件: Lepunafusp alfa---1件: 19 💬
65 Leucine 2件: L-leucine; Leucine1件: Leucine 💬 --13件: 5, 6, 7, 18, 19, 65, 96, 97, 127, 280, 283, 284, 299 💬
66 Leucovorin 2件: Folinic acid; Leucovorin3件: Leucovorin calcium ,
Folinic acid ,
Folinic acid calcium salt pentahydrate 💬 		--3件: 13, 19, 46 💬
67 Lisinopril 1件: Lisinopril2件: Lisinopril ,
Lisinopril 💬 		1件: ACE 💬 6件: Chagas disease, Coronavirus disease, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬9件: 19, 46, 49, 57, 66, 67, 113, 222, 223 💬
68 Loratadine 1件: Loratadine1件: Loratadine 💬 1件: HRH1 💬 4件: Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction 💬5件: 13, 19, 46, 89, 98 💬
69 Losartan 2件: Losartan; LOSARTAN POTASSIUM2件: Losartan potassium ,
Losartan 💬 		1件: AGTR1 💬 17件: AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Hormone signaling, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬20件: 17, 19, 36, 46, 57, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 223, 299 💬
70 Lucerastat 1件: Lucerastat1件: Lucerastat 💬 1件: UGCG 💬 2件: Cornified envelope formation, Sphingolipid metabolism 💬1件: 19 💬
71 LY3884961 1件: LY3884961---2件: 6, 19 💬
72 Melphalan 2件: Melphalan; Melphalan Hydrochloride2件: Melphalan ,
Melphalan hydrochloride 💬 		--19件: 11, 13, 14, 19, 20, 28, 34, 46, 60, 62, 65, 96, 107, 164, 222, 234, 284, 285, 299 💬
73 Methotrexate 5件: Methotrexat; Methotrexate; METHOTREXATE SODIUM; Methylaminopterin; METOTREXATO2件: Methotrexate ,
Methotrexate sodium 💬 		2件: DHFR,
DHFR2 💬 		3件: Folate biosynthesis, Folate transport and metabolism, One carbon pool by folate 💬41件: 11, 13, 14, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 54, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 223, 240, 256, 270, 271, 284, 285, 286, 326, 331 💬
74 Methylprednisolone 3件: Methylprednisolon; Methylprednisolone; Methylprednisolone acetate2件: Methylprednisolone ,
Methylprednisolone acetate 💬 		1件: NR3C1 💬 1件: Neuroactive ligand-receptor interaction 💬51件: 2, 6, 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 95, 96, 97, 111, 127, 145, 162, 164, 211, 222, 223, 224, 271, 283, 284, 285, 296, 300 💬
75 Migalastat 2件: MIGALASTAT; MIGALASTAT HYDROCHLORIDE2件: Migalastat hydrochloride ,
Migalastat 💬 		1件: GLA 💬 5件: Galactose metabolism, Glycerolipid metabolism, Glycosphingolipid biosynthesis - globo and isoglobo series, Lysosome biogenesis, Sphingolipid metabolism 💬1件: 19 💬
76 Miglustat 2件: AT2221; Miglustat1件: Miglustat 💬 1件: UGCG 💬 2件: Cornified envelope formation, Sphingolipid metabolism 💬3件: 19, 256, 299 💬
77 Montelukast 2件: Montelukast; MONTELUKAST SODIUM2件: Montelukast sodium ,
Montelukast 💬 		1件: CYSLTR1 💬 2件: Calcium signaling pathway, Neuroactive ligand-receptor interaction 💬10件: 6, 13, 19, 46, 61, 63, 85, 98, 222, 228 💬
78 Mycophenolate mofetil 1件: Mycophenolate Mofetil2件: Mycophenolate mofetil ,
Mycophenolate mofetil hydrochloride 💬 		2件: IMPDH1,
IMPDH2 💬 		2件: Drug metabolism - other enzymes, Purine metabolism 💬38件: 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 46, 49, 51, 53, 57, 60, 61, 62, 63, 65, 66, 93, 95, 96, 118, 162, 164, 222, 223, 224, 226, 234, 283, 284, 285, 300 💬
79 NGN-101 1件: NGN-101---1件: 19 💬
80 Nizubaglustat 2件: AZ-3102; Nizubaglustat1件: Nizubaglustat 💬 2件: GBA2,
UGCG 💬 		3件: Cornified envelope formation, Other glycan degradation, Sphingolipid metabolism 💬1件: 19 💬
81 Odiparcil 1件: Odiparcil---1件: 19 💬
82 Olenasufligene relduparvovec 2件: LYS-SAF302; OLENASUFLIGENE RELDUPARVOVEC---1件: 19 💬
83 Olipudase alfa 1件: OLIPUDASE ALFA1件: Olipudase alfa 💬 1件: SMPD1 💬 4件: Lysosome biogenesis, Necroptosis, Sphingolipid metabolism, Sphingolipid signaling pathway 💬1件: 19 💬
84 OTL-203 1件: OTL-203---1件: 19 💬
85 Oxygen 1件: Oxygen1件: Oxygen 💬 --30件: 6, 13, 15, 19, 22, 36, 46, 49, 70, 71, 85, 86, 88, 90, 96, 97, 129, 149, 168, 193, 211, 226, 230, 235, 269, 271, 294, 298, 299, 330 💬
86 Pabinafusp alfa 1件: Pabinafusp alfa1件: Pabinafusp alfa 💬 2件: IDS,
TFRC 💬 		8件: Endocytosis, Ferroptosis, Glycosaminoglycan degradation, HIF-1 signaling pathway, Hematopoietic cell lineage, Lysosome biogenesis, TGF-beta signaling pathway, Virion - Lassa virus and SFTS virus 💬1件: 19 💬
87 Paricalcitol 1件: Paricalcitol1件: Paricalcitol 💬 1件: VDR 💬 5件: Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬5件: 19, 66, 218, 238, 298 💬
88 PBGM01 1件: PBGM01---1件: 19 💬
89 PBKR03 1件: PBKR03---1件: 19 💬
90 Pegunigalsidase alfa 1件: PEGUNIGALSIDASE ALFA1件: Pegunigalsidase alfa 💬 1件: GLA 💬 5件: Galactose metabolism, Glycerolipid metabolism, Glycosphingolipid biosynthesis - globo and isoglobo series, Lysosome biogenesis, Sphingolipid metabolism 💬1件: 19 💬
91 Pentosan polysulfate 2件: Pentosan polysulfate; PENTOSAN POLYSULFATE SODIUM1件: Pentosan polysulfate sodium 💬 --3件: 19, 26, 226 💬
92 Prednisone 2件: PREDNISONA; PREDNISONE1件: Prednisone 💬 1件: NR3C1 💬 1件: Neuroactive ligand-receptor interaction 💬58件: 2, 11, 13, 14, 18, 19, 26, 28, 35, 40, 41, 42, 43, 44, 45, 46, 48, 49, 50, 51, 53, 60, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 90, 93, 95, 96, 97, 113, 127, 145, 162, 164, 205, 222, 223, 224, 228, 251, 269, 283, 284, 285, 288, 299, 300, 303, 307, 331 💬
93 Pyrimethamine 1件: Pyrimethamine1件: Pyrimethamine 💬 --4件: 2, 4, 19, 65 💬
94 Rebisufligene etisparvovec 3件: ABO-102; Rebisufligene etisparvovec; UX111---1件: 19 💬
95 Recombinant human arylsulfatase A 1件: RECOMBINANT HUMAN ARYLSULFATASE A---1件: 19 💬
96 RGX-111 1件: RGX-111---1件: 19 💬
97 RGX-121 1件: RGX-121---1件: 19 💬
98 Rimiducid 1件: Rimiducid1件: Rimiducid 💬 1件: CASP9 💬 34件: Alzheimer disease, Amyotrophic lateral sclerosis, Apoptosis, Apoptosis - multiple species, Colorectal cancer, Endometrial cancer, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Huntington disease, Influenza A, Kaposi sarcoma-associated herpesvirus infection, Legionellosis, Lipid and atherosclerosis, Measles, Non-small cell lung cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Parkinson disease, Pathogenic Escherichia coli infection, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Prostate cancer, Small cell lung cancer, Thyroid hormone signaling pathway, Toxoplasmosis, Tuberculosis, VEGF signaling pathway, Viral myocarditis, p53 signaling pathway 💬7件: 19, 49, 60, 65, 284, 285, 326 💬
99 Rituximab 1件: RITUXIMAB1件: Rituximab 💬 1件: MS4A1 💬 1件: Hematopoietic cell lineage 💬54件: 11, 13, 14, 19, 26, 34, 35, 36, 40, 41, 42, 43, 44, 45, 46, 48, 49, 50, 51, 52, 53, 55, 56, 60, 61, 62, 63, 64, 65, 66, 83, 84, 85, 86, 88, 93, 94, 96, 97, 162, 172, 222, 223, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331 💬
100 Rivogenlecleucel 1件: Rivogenlecleucel1件: Rivogenlecleucel 💬 --6件: 19, 60, 65, 284, 285, 326 💬
101 Sebelipase alfa 3件: SBC-102; Sebelipasa Alfa; Sebelipase Alfa1件: Sebelipase alfa 💬 1件: LIPA 💬 4件: Cholesterol metabolism, Efferocytosis, Lysosome biogenesis, Steroid biosynthesis 💬1件: 19 💬
102 Sirolimus 2件: Rapamycin; Sirolimus1件: Sirolimus 💬 1件: MTOR 💬 52件: AMPK signaling pathway, Acute myeloid leukemia, Adipocytokine signaling pathway, Alzheimer disease, Amyotrophic lateral sclerosis, Apelin signaling pathway, Autophagy - animal, Autophagy - other, Breast cancer, Cellular senescence, Central carbon metabolism in cancer, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Diabetic cardiomyopathy, ErbB signaling pathway, Gastric cancer, Glioma, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatocellular carcinoma, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Huntington disease, Insulin resistance, Insulin signaling pathway, Integrated stress response (ISR) signaling pathway, Integrin signaling, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Longevity regulating pathway, Longevity regulating pathway - multiple species, Lysosome biogenesis, MicroRNAs in cancer, Neutrophil extracellular trap formation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Shigellosis, Spinocerebellar ataxia, Th17 cell differentiation, Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus, mTOR signaling pathway 💬46件: 6, 13, 15, 17, 19, 21, 34, 35, 36, 46, 48, 49, 51, 54, 57, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 97, 98, 111, 127, 137, 157, 158, 192, 222, 223, 227, 277, 278, 279, 280, 281, 283, 285, 300, 331 💬
103 SOBI-003 0件: ---1件: 19 💬
104 Sofosbuvir 1件: Sofosbuvir1件: Sofosbuvir 💬 --1件: 19 💬
105 TAK-611 1件: TAK-611---1件: 19 💬
106 Taliglucerase alfa 2件: PrGCD; TALIGLUCERASE ALFA1件: Taliglucerase alfa 💬 1件: GBA1 💬 4件: Cornified envelope formation, Lysosome biogenesis, Other glycan degradation, Sphingolipid metabolism 💬1件: 19 💬
107 Thiotepa 1件: Thiotepa1件: Thiotepa 💬 --14件: 13, 19, 20, 28, 46, 51, 60, 65, 85, 96, 107, 164, 284, 285 💬
108 Tividenofusp alfa 1件: Tividenofusp alfa1件: Tividenofusp alfa 💬 2件: IDS,
TFRC 💬 		8件: Endocytosis, Ferroptosis, Glycosaminoglycan degradation, HIF-1 signaling pathway, Hematopoietic cell lineage, Lysosome biogenesis, TGF-beta signaling pathway, Virion - Lassa virus and SFTS virus 💬1件: 19 💬
109 Tralesinidase alfa 2件: RHNAGLU-IGF2; Tralesinidase alfa1件: Tralesinidase alfa 💬 2件: IGF2,
NAGLU 💬 		9件: Glycosaminoglycan degradation, Hepatocellular carcinoma, Hormone signaling, Lysosome biogenesis, MAPK signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer, Proteoglycans in cancer, Ras signaling pathway 💬1件: 19 💬
110 Treosulfan 1件: Treosulfan1件: Treosulfan 💬 --6件: 13, 19, 62, 65, 284, 286 💬
111 Tropicamide 1件: Tropicamide1件: Tropicamide 💬 5件: CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5 💬 		14件: Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬2件: 6, 19 💬
112 TSHA-101 1件: TSHA-101---1件: 19 💬
113 Velaglucerase alfa 2件: GA-GCB; VELAGLUCERASE ALFA1件: Velaglucerase alfa 💬 1件: GBA1 💬 4件: Cornified envelope formation, Lysosome biogenesis, Other glycan degradation, Sphingolipid metabolism 💬1件: 19 💬
114 Velmanase alfa 3件: LAMAZYM; RhLAMAN; VELMANASE ALFA1件: Velmanase alfa 💬 1件: MAN2B1 💬 2件: Lysosome biogenesis, Other glycan degradation 💬1件: 19 💬
115 Venglustat 2件: Venglustat; Venglustat malate2件: Venglustat ,
Venglustat malate 💬 		1件: UGCG 💬 2件: Cornified envelope formation, Sphingolipid metabolism 💬3件: 6, 19, 67 💬
116 Vestronidase alfa 2件: Recombinant human beta-glucuronidase; Vestronidase alfa1件: Vestronidase alfa 💬 1件: GUSB 💬 6件: Ascorbate and aldarate metabolism, Drug metabolism - other enzymes, Glycosaminoglycan degradation, Lysosome biogenesis, Pentose and glucuronate interconversions, Porphyrin metabolism 💬1件: 19 💬
117 Vitamin D 1件: Vitamin D---26件: 3, 6, 13, 15, 19, 41, 43, 44, 46, 49, 50, 68, 74, 93, 95, 96, 97, 98, 179, 222, 228, 235, 256, 274, 298, 299 💬
118 Vitamin E 1件: Vitamin E1件: Vitamin E 💬 --12件: 2, 6, 13, 19, 20, 46, 90, 96, 97, 206, 299, 317 💬
119 Vosoritide 1件: Vosoritide1件: Vosoritide 💬 1件: NPR2 💬 5件: Hormone signaling, Oxytocin signaling pathway, Purine metabolism, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬3件: 19, 195, 276 💬
120 Warfarin 3件: Warfarin; Warfarin Potassium; Warfarin Sodium3件: Warfarin sodium ,
Warfarin potassium ,
Warfarin 💬 		2件: NQO1,
VKORC1 💬 		5件: Chemical carcinogenesis - reactive oxygen species, Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Pathways in cancer, Ubiquinone and other terpenoid-quinone biosynthesis 💬15件: 6, 8, 13, 19, 46, 48, 49, 66, 85, 86, 88, 91, 96, 97, 222 💬
121 Water 1件: Water1件: Water 💬 --36件: 2, 3, 5, 6, 13, 17, 19, 22, 35, 46, 49, 51, 53, 56, 57, 62, 63, 64, 65, 66, 67, 70, 72, 85, 86, 96, 97, 206, 215, 225, 226, 230, 240, 274, 278, 299 💬