Target Gene/Pathway Pathway / Gene

  

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No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank 指定難病告示番号
1 CRHR1 💬 5件: cAMP signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Long-term depression, Cushing syndrome Corticorelin 💬 Corticorelin 2件: 75, 205 💬
2 CRHR2 💬 4件: cAMP signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Cushing syndrome Corticorelin 💬 Corticorelin 2件: 75, 205 💬
3 GABRA 💬 7件: Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Brexanolone 💬 Brexanolone 2件: 6, 205 💬
4 GABRA 💬 7件: Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Brexanolone 💬 Brexanolone 2件: 6, 205 💬
5 GABRA 💬 7件: Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Brexanolone 💬 Brexanolone 2件: 6, 205 💬
6 GABRA 💬 7件: Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Brexanolone 💬 Brexanolone 2件: 6, 205 💬
7 GABRA 💬 7件: Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Brexanolone 💬 Brexanolone 2件: 6, 205 💬
8 GABRA 💬 7件: Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Brexanolone 💬 Brexanolone 2件: 6, 205 💬
9 GABRB 💬 7件: Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Retrograde endocannabinoid signaling, Serotonergic synapse, GABAergic synapse, Morphine addiction, Nicotine addiction Brexanolone 💬 Brexanolone 2件: 6, 205 💬
10 GABRB 💬 7件: Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Retrograde endocannabinoid signaling, Serotonergic synapse, GABAergic synapse, Morphine addiction, Nicotine addiction Brexanolone 💬 Brexanolone 2件: 6, 205 💬
11 GABRB 💬 7件: Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Retrograde endocannabinoid signaling, Serotonergic synapse, GABAergic synapse, Morphine addiction, Nicotine addiction Brexanolone 💬 Brexanolone 2件: 6, 205 💬
12 GABRD 💬 6件: Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Brexanolone 💬 Brexanolone 2件: 6, 205 💬
13 GABRE 💬 6件: Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Brexanolone 💬 Brexanolone 2件: 6, 205 💬
14 GABRG 💬 6件: Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Brexanolone 💬 Brexanolone 2件: 6, 205 💬
15 GABRG 💬 6件: Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Brexanolone 💬 Brexanolone 2件: 6, 205 💬
16 GABRG 💬 6件: Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Brexanolone 💬 Brexanolone 2件: 6, 205 💬
17 GABRP 💬 6件: Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Brexanolone 💬 Brexanolone 2件: 6, 205 💬
18 GABRQ 💬 6件: Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Brexanolone 💬 Brexanolone 2件: 6, 205 💬
19 GRIN1 💬 19件: Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Huntington disease, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism Memantine hydrochloride 💬 Memantine 8件: 2, 6, 8, 13, 49, 127, 205, 206 💬
20 GRIN1 💬 19件: Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Huntington disease, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism Memantine 💬 Memantine 8件: 2, 6, 8, 13, 49, 127, 205, 206 💬
21 GRIN2A 💬 20件: Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Dopaminergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism, Systemic lupus erythematosus Memantine 💬 Memantine 8件: 2, 6, 8, 13, 49, 127, 205, 206 💬
22 GRIN2A 💬 20件: Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Dopaminergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism, Systemic lupus erythematosus Memantine hydrochloride 💬 Memantine 8件: 2, 6, 8, 13, 49, 127, 205, 206 💬
23 GRIN2B 💬 21件: Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Dopaminergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Huntington disease, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism, Systemic lupus erythematosus Memantine hydrochloride 💬 Memantine 8件: 2, 6, 8, 13, 49, 127, 205, 206 💬
24 GRIN2B 💬 21件: Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Dopaminergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Huntington disease, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism, Systemic lupus erythematosus Memantine 💬 Memantine 8件: 2, 6, 8, 13, 49, 127, 205, 206 💬
25 GRIN2C 💬 16件: Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism Memantine hydrochloride 💬 Memantine 8件: 2, 6, 8, 13, 49, 127, 205, 206 💬
26 GRIN2C 💬 16件: Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism Memantine 💬 Memantine 8件: 2, 6, 8, 13, 49, 127, 205, 206 💬
27 GRIN2D 💬 16件: Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism Memantine 💬 Memantine 8件: 2, 6, 8, 13, 49, 127, 205, 206 💬
28 GRIN2D 💬 16件: Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism Memantine hydrochloride 💬 Memantine 8件: 2, 6, 8, 13, 49, 127, 205, 206 💬
29 MC2R 💬 6件: cAMP signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome Corticotropin, repository 💬 Corticotropin 11件: 13, 46, 50, 66, 75, 78, 81, 84, 145, 205, 222 💬
30 MC2R 💬 6件: cAMP signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome Corticotropin 💬 Corticotropin 11件: 13, 46, 50, 66, 75, 78, 81, 84, 145, 205, 222 💬
31 NR3C1 💬 1件: Neuroactive ligand-receptor interaction Prednisone 💬 Prednisone 54件: 2, 11, 13, 14, 18, 19, 26, 28, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 60, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 90, 93, 95, 96, 97, 113, 145, 162, 164, 205, 222, 224, 228, 251, 269, 283, 285, 288, 299, 300, 303, 307, 331 💬