Target Gene/Pathway Pathway / Gene

  

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No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank 指定難病告示番号
1 ACHE 💬 3件: Glycerophospholipid metabolism, Neuroactive ligand signaling, Cholinergic synapse Pyridostigmine bromide 💬 Pyridostigmine 5件: 3, 6, 11, 51, 256 💬
2 ADRB2 💬 11件: Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Adrenergic signaling in cardiomyocytes, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Chemical carcinogenesis - receptor activation Clenbuterol hydrochloride 💬 Clenbuterol 6件: 1, 2, 6, 57, 113, 256 💬
3 ADRB2 💬 11件: Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Adrenergic signaling in cardiomyocytes, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Chemical carcinogenesis - receptor activation Albuterol 💬 Albuterol 9件: 12, 13, 86, 89, 113, 231, 256, 299, 340 💬
4 ADRB2 💬 11件: Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Adrenergic signaling in cardiomyocytes, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Chemical carcinogenesis - receptor activation Albuterol sulfate 💬 Albuterol 9件: 12, 13, 86, 89, 113, 231, 256, 299, 340 💬
5 ADRB2 💬 11件: Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Adrenergic signaling in cardiomyocytes, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Chemical carcinogenesis - receptor activation Clenbuterol 💬 Clenbuterol 6件: 1, 2, 6, 57, 113, 256 💬
6 CSF3R 💬 5件: Cytokine-cytokine receptor interaction, PI3K-Akt signaling pathway, JAK-STAT signaling pathway, Hematopoietic cell lineage, Pathways in cancer Filgrastim 💬 Filgrastim 30件: 2, 6, 13, 25, 26, 28, 34, 35, 38, 40, 41, 42, 45, 46, 47, 49, 51, 60, 62, 63, 65, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬
7 DHFR 💬 3件: One carbon pool by folate, Folate biosynthesis, Folate transport and metabolism Methotrexate sodium 💬 Methotrexate 41件: 11, 13, 14, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 54, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 223, 240, 256, 270, 271, 284, 285, 286, 326, 331 💬
8 DHFR 💬 3件: One carbon pool by folate, Folate biosynthesis, Folate transport and metabolism Methotrexate 💬 Methotrexate 41件: 11, 13, 14, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 54, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 223, 240, 256, 270, 271, 284, 285, 286, 326, 331 💬
9 DHFR2 💬 3件: One carbon pool by folate, Folate biosynthesis, Folate transport and metabolism Methotrexate 💬 Methotrexate 41件: 11, 13, 14, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 54, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 223, 240, 256, 270, 271, 284, 285, 286, 326, 331 💬
10 DHFR2 💬 3件: One carbon pool by folate, Folate biosynthesis, Folate transport and metabolism Methotrexate sodium 💬 Methotrexate 41件: 11, 13, 14, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 54, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 223, 240, 256, 270, 271, 284, 285, 286, 326, 331 💬
11 GAA 💬 3件: Galactose metabolism, Starch and sucrose metabolism, Lysosome biogenesis Avalglucosidase alfa 💬 Avalglucosidase alfa 1件: 256 💬
12 GAA 💬 3件: Galactose metabolism, Starch and sucrose metabolism, Lysosome biogenesis Alglucosidase alfa 💬 Alglucosidase alfa 1件: 256 💬
13 GAA 💬 3件: Galactose metabolism, Starch and sucrose metabolism, Lysosome biogenesis Cipaglucosidase alfa 💬 Cipaglucosidase alfa 1件: 256 💬
14 GAA 💬 3件: Galactose metabolism, Starch and sucrose metabolism, Lysosome biogenesis Duvoglustat hydrochloride 💬 Duvoglustat 1件: 256 💬
15 GAA 💬 3件: Galactose metabolism, Starch and sucrose metabolism, Lysosome biogenesis Duvoglustat 💬 Duvoglustat 1件: 256 💬
16 HRH1 💬 4件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Inflammatory mediator regulation of TRP channels Diphenhydramine hydrochloride 💬 Diphenhydramine 12件: 11, 13, 19, 49, 51, 63, 70, 86, 96, 222, 256, 300 💬
17 HRH1 💬 4件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Inflammatory mediator regulation of TRP channels Diphenhydramine salicylate 💬 Diphenhydramine 12件: 11, 13, 19, 49, 51, 63, 70, 86, 96, 222, 256, 300 💬
18 HRH1 💬 4件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Inflammatory mediator regulation of TRP channels Diphenhydramine 💬 Diphenhydramine 12件: 11, 13, 19, 49, 51, 63, 70, 86, 96, 222, 256, 300 💬
19 HRH1 💬 4件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Inflammatory mediator regulation of TRP channels Diphenhydramine citrate 💬 Diphenhydramine 12件: 11, 13, 19, 49, 51, 63, 70, 86, 96, 222, 256, 300 💬
20 IDUA 💬 2件: Glycosaminoglycan degradation, Lysosome biogenesis Laronidase 💬 Laronidase 2件: 19, 256 💬
21 MS4A1 💬 1件: Hematopoietic cell lineage Rituximab 💬 Rituximab 54件: 11, 13, 14, 19, 26, 34, 35, 36, 40, 41, 42, 43, 44, 45, 46, 48, 49, 50, 51, 52, 53, 55, 56, 60, 61, 62, 63, 64, 65, 66, 83, 84, 85, 86, 88, 93, 94, 96, 97, 162, 172, 222, 223, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331 💬
22 PSMB5 💬 8件: Proteasome, Alzheimer disease, Parkinson disease, Amyotrophic lateral sclerosis, Huntington disease, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases Bortezomib 💬 Bortezomib 19件: 11, 13, 26, 28, 46, 49, 51, 61, 63, 64, 66, 172, 222, 223, 228, 256, 283, 288, 331 💬
23 PTGS1 💬 4件: Arachidonic acid metabolism, Platelet activation, Serotonergic synapse, Regulation of lipolysis in adipocytes Acetaminophen 💬 Acetaminophen 19件: 11, 13, 19, 34, 35, 46, 49, 51, 63, 70, 77, 86, 96, 222, 231, 256, 271, 300, 337 💬
24 PTGS2 💬 22件: Arachidonic acid metabolism, NF-kappa B signaling pathway, Efferocytosis, VEGF signaling pathway, C-type lectin receptor signaling pathway, IL-17 signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Ovarian steroidogenesis, Oxytocin signaling pathway, Regulation of lipolysis in adipocytes, Alzheimer disease, Pathways of neurodegeneration - multiple diseases, Leishmaniasis, Human cytomegalovirus infection, Human papillomavirus infection, Kaposi sarcoma-associated herpesvirus infection, Pathways in cancer, Chemical carcinogenesis - DNA adducts, MicroRNAs in cancer, Small cell lung cancer Acetaminophen 💬 Acetaminophen 19件: 11, 13, 19, 34, 35, 46, 49, 51, 63, 70, 77, 86, 96, 222, 231, 256, 271, 300, 337 💬
25 SCN1A 💬 1件: Dopaminergic synapse Lidocaine hydrochloride monohydrate 💬 Lidocaine 14件: 6, 13, 22, 34, 46, 51, 70, 86, 107, 168, 226, 231, 256, 298 💬
26 SCN1A 💬 1件: Dopaminergic synapse Lidocaine 💬 Lidocaine 14件: 6, 13, 22, 34, 46, 51, 70, 86, 107, 168, 226, 231, 256, 298 💬
27 SCN1A 💬 1件: Dopaminergic synapse Lidocaine hydrochloride 💬 Lidocaine 14件: 6, 13, 22, 34, 46, 51, 70, 86, 107, 168, 226, 231, 256, 298 💬
28 SCN2A 💬 1件: Taste transduction Lidocaine 💬 Lidocaine 14件: 6, 13, 22, 34, 46, 51, 70, 86, 107, 168, 226, 231, 256, 298 💬
29 SCN2A 💬 1件: Taste transduction Lidocaine hydrochloride monohydrate 💬 Lidocaine 14件: 6, 13, 22, 34, 46, 51, 70, 86, 107, 168, 226, 231, 256, 298 💬
30 SCN2A 💬 1件: Taste transduction Lidocaine hydrochloride 💬 Lidocaine 14件: 6, 13, 22, 34, 46, 51, 70, 86, 107, 168, 226, 231, 256, 298 💬
31 SCN3A 💬 1件: Taste transduction Lidocaine 💬 Lidocaine 14件: 6, 13, 22, 34, 46, 51, 70, 86, 107, 168, 226, 231, 256, 298 💬
32 SCN3A 💬 1件: Taste transduction Lidocaine hydrochloride 💬 Lidocaine 14件: 6, 13, 22, 34, 46, 51, 70, 86, 107, 168, 226, 231, 256, 298 💬
33 SCN3A 💬 1件: Taste transduction Lidocaine hydrochloride monohydrate 💬 Lidocaine 14件: 6, 13, 22, 34, 46, 51, 70, 86, 107, 168, 226, 231, 256, 298 💬
34 SCN5A 💬 2件: Adrenergic signaling in cardiomyocytes, Cadherin signaling Lidocaine 💬 Lidocaine 14件: 6, 13, 22, 34, 46, 51, 70, 86, 107, 168, 226, 231, 256, 298 💬
35 SCN5A 💬 2件: Adrenergic signaling in cardiomyocytes, Cadherin signaling Lidocaine hydrochloride 💬 Lidocaine 14件: 6, 13, 22, 34, 46, 51, 70, 86, 107, 168, 226, 231, 256, 298 💬
36 SCN5A 💬 2件: Adrenergic signaling in cardiomyocytes, Cadherin signaling Lidocaine hydrochloride monohydrate 💬 Lidocaine 14件: 6, 13, 22, 34, 46, 51, 70, 86, 107, 168, 226, 231, 256, 298 💬
37 SCN8A 💬 1件: IgSF CAM signaling Lidocaine hydrochloride monohydrate 💬 Lidocaine 14件: 6, 13, 22, 34, 46, 51, 70, 86, 107, 168, 226, 231, 256, 298 💬
38 SCN8A 💬 1件: IgSF CAM signaling Lidocaine 💬 Lidocaine 14件: 6, 13, 22, 34, 46, 51, 70, 86, 107, 168, 226, 231, 256, 298 💬
39 SCN8A 💬 1件: IgSF CAM signaling Lidocaine hydrochloride 💬 Lidocaine 14件: 6, 13, 22, 34, 46, 51, 70, 86, 107, 168, 226, 231, 256, 298 💬
40 SCN9A 💬 1件: Taste transduction Lidocaine 💬 Lidocaine 14件: 6, 13, 22, 34, 46, 51, 70, 86, 107, 168, 226, 231, 256, 298 💬
41 SCN9A 💬 1件: Taste transduction Lidocaine hydrochloride 💬 Lidocaine 14件: 6, 13, 22, 34, 46, 51, 70, 86, 107, 168, 226, 231, 256, 298 💬
42 SCN9A 💬 1件: Taste transduction Lidocaine hydrochloride monohydrate 💬 Lidocaine 14件: 6, 13, 22, 34, 46, 51, 70, 86, 107, 168, 226, 231, 256, 298 💬
43 UGCG 💬 2件: Sphingolipid metabolism, Cornified envelope formation Miglustat 💬 Miglustat 3件: 19, 256, 299 💬