Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank Drug (Description in trials) KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1 Ampreloxetine [1] Ampreloxetine[1] Ampreloxetine 💬 [2] SLC6A2,
SLC6A4 💬 		[3] Neuroactive ligand signaling, Serotonergic synapse, Synaptic vesicle cycle 💬[2] 6, 17 💬
2 Angiotensin II [2] Angiotensin; Angiotensin II[3] Angiotensin II ,
Angiotensin II ,
Angiotensin II acetate 💬 		[2] AGTR1,
AGTR2 💬 		[17] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Hormone signaling, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[7] 17, 46, 49, 66, 218, 222, 224 💬
3 Botulinum toxin type A [5] Botulinum toxin A; Botulinum toxin type A; BTX-A; Incobotulinumtoxina; Onabotulinumtoxina[2] Botulinum toxin type A ,
Prabotulinumtoxin A 💬 		[1] SNAP25 💬 [2] Insulin secretion, Synaptic vesicle cycle 💬[14] 2, 5, 6, 7, 13, 15, 17, 47, 51, 70, 113, 149, 171, 226 💬
4 Captopril [1] Captopril[1] Captopril 💬 [1] ACE 💬 [6] Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬[7] 17, 46, 86, 96, 97, 107, 271 💬
5 Carbidopa [1] Carbidopa[1] Carbidopa 💬 [1] DDC 💬 [8] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬[5] 6, 13, 17, 140, 201 💬
6 Domperidone [1] Domperidone[2] Domperidone ,
Domperidone maleate 💬 		[1] DRD2 💬 [10] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[5] 6, 13, 17, 51, 230 💬
7 Droxidopa [2] Droxidopa; L-dops[1] Droxidopa 💬 [9] ADRA1A,
ADRA1B,
ADRA1D,
ADRA2A,
ADRA2B,
ADRA2C,
ADRB1,
ADRB2,
ADRB3 💬 		[16] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[5] 5, 6, 17, 169, 170 💬
8 Emeramide [1] Emeramide---[2] 5, 17 💬
9 Entacapone [2] Entacapona; Entacapone[1] Entacapone 💬 [1] COMT 💬 [3] Dopaminergic synapse, Steroid hormone biosynthesis, Tyrosine metabolism 💬[2] 6, 17 💬
10 Epigallocatechin gallate [2] Egcg; Epigallocatechin-3-gallate---[8] 6, 8, 13, 17, 28, 85, 206, 299 💬
11 Exenatide [1] Exenatide[1] Exenatide 💬 [1] GLP1R 💬 [4] Hormone signaling, Insulin secretion, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[5] 6, 17, 78, 193, 233 💬
12 Fipamezole [1] Fipamezole---[2] 6, 17 💬
13 Fludrocortisone [1] Fludrocortisone[2] Fludrocortisone acetate ,
Fludrocortisone 💬 		[1] NR3C2 💬 [1] Aldosterone-regulated sodium reabsorption 💬[3] 6, 17, 81 💬
14 Flumazenil [1] Flumazenil[1] Flumazenil 💬 [16] GABRA,
GABRA,
GABRA,
GABRA,
GABRA,
GABRA,
GABRB,
GABRB,
GABRB,
GABRD,
GABRE,
GABRG,
GABRG,
GABRG,
GABRP,
GABRQ 💬 		[8] GABAergic synapse, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[5] 6, 13, 17, 18, 206 💬
15 Fluoxetine [3] Fluoxetine; Fluoxetine hydrochloride; Fluoxétine[2] Fluoxetine ,
Fluoxetine hydrochloride 💬 		[1] SLC6A4 💬 [3] Neuroactive ligand signaling, Serotonergic synapse, Synaptic vesicle cycle 💬[3] 13, 17, 86 💬
16 Flutemetamol [1] Flutemetamol---[5] 5, 6, 7, 17, 127 💬
17 Flutemetamol (18F) [1] Flutemetamol[1] Flutemetamol F 18 💬 --[5] 5, 6, 7, 17, 127 💬
18 Foralumab [1] Foralumab---[3] 13, 17, 96 💬
19 Green tea leaf [3] Green TEA; Green TEA leaf; TEA extract[1] Green tea leaf 💬 --[5] 6, 17, 28, 46, 96 💬
20 Hydrogen [1] Hydrogen---[7] 5, 6, 13, 17, 97, 226, 288 💬
21 Levodopa [2] L-dopa; Levodopa[1] Levodopa 💬 [5] DRD1,
DRD2,
DRD3,
DRD4,
DRD5 💬 		[13] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[6] 6, 17, 90, 140, 164, 201 💬
22 Lithium carbonate [1] Lithium carbonate[1] Lithium carbonate 💬 --[6] 2, 13, 17, 18, 127, 310 💬
23 Losartan [2] Losartan; Losartan potassium[2] Losartan potassium ,
Losartan 💬 		[1] AGTR1 💬 [17] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Hormone signaling, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
24 Metoprolol [2] Metoprolol; Metoprolol succinate[4] Metoprolol tartrate ,
Metoprolol succinate ,
Metoprolol ,
Metoprolol fumarate 💬 		[1] ADRB1 💬 [13] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[6] 17, 57, 58, 113, 193, 226 💬
25 Midodrine [2] Midodrine; Midodrine hydrochloride[2] Midodrine hydrochloride ,
Midodrine 💬 		[3] ADRA1A,
ADRA1B,
ADRA1D 💬 		[9] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[3] 6, 17, 58 💬
26 Nebivolol [1] Nebivolol[2] Nebivolol ,
Nebivolol hydrochloride 💬 		[1] ADRB1 💬 [13] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[4] 17, 85, 113, 167 💬
27 Nicotinamide [2] Niacinamide; Nicotinamide[1] Niacinamide 💬 --[20] 2, 5, 6, 7, 8, 13, 17, 18, 21, 46, 49, 60, 63, 65, 67, 85, 97, 107, 162, 191 💬
28 Nicotinamide riboside [2] Nicotinamide riboside; Nicotinamide riboside chloride---[14] 2, 5, 6, 7, 8, 17, 18, 21, 49, 60, 65, 85, 97, 191 💬
29 Nitrogen [1] Nitrogen[1] Nitrogen 💬 --[5] 5, 6, 17, 211, 299 💬
30 Pittsburgh Compound B [2] C-11 PIB; Pittsburgh compound B---[3] 6, 17, 127 💬
31 Pseudoephedrine [1] Pseudoephedrine[3] Pseudoephedrine hydrochloride ,
Pseudoephedrine sulfate ,
Pseudoephedrine 💬 		[9] ADRA1A,
ADRA1B,
ADRA1D,
ADRA2A,
ADRA2B,
ADRA2C,
ADRB1,
ADRB2,
ADRB3 💬 		[16] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 17 💬
32 Rasagiline [2] Rasagiline; Rasagiline mesylate[3] Rasagiline mesylate ,
Rasagiline ,
Rasagiline tartrate 💬 		[1] MAO 💬 [13] Alcoholism, Amphetamine addiction, Arginine and proline metabolism, Cocaine addiction, Dopaminergic synapse, Drug metabolism - cytochrome P450, Glycine, serine and threonine metabolism, Histidine metabolism, Parkinson disease, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬[5] 2, 5, 6, 17, 66 💬
33 Rifampin [2] Rifampicin; Rifampin[2] Rifampin ,
Rifampicin sodium 💬 		--[10] 6, 13, 17, 46, 84, 86, 93, 97, 299, 338 💬
34 Riluzole [1] Riluzole[1] Riluzole 💬 [14] GRIA1,
GRIA2,
GRIA3,
GRIA4,
GRIK1,
GRIK2,
GRIK3,
GRIK4,
GRIK5,
GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬 		[24] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term depression, Long-term potentiation, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Retrograde endocannabinoid signaling, Spinocerebellar ataxia, Systemic lupus erythematosus, Transcriptional misregulation in cancer, cAMP signaling pathway 💬[8] 2, 3, 5, 8, 13, 17, 203, 206 💬
35 Safinamide [2] Safinamida; Safinamide[2] Safinamide ,
Safinamide mesylate 💬 		[1] MAO 💬 [13] Alcoholism, Amphetamine addiction, Arginine and proline metabolism, Cocaine addiction, Dopaminergic synapse, Drug metabolism - cytochrome P450, Glycine, serine and threonine metabolism, Histidine metabolism, Parkinson disease, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬[2] 6, 17 💬
36 Sirolimus [2] Rapamycin; Sirolimus[1] Sirolimus 💬 [1] MTOR 💬 [49] AMPK signaling pathway, Acute myeloid leukemia, Adipocytokine signaling pathway, Alzheimer disease, Amyotrophic lateral sclerosis, Apelin signaling pathway, Autophagy - animal, Autophagy - other, Breast cancer, Cellular senescence, Central carbon metabolism in cancer, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Diabetic cardiomyopathy, ErbB signaling pathway, Gastric cancer, Glioma, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatocellular carcinoma, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Huntington disease, Insulin resistance, Insulin signaling pathway, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Longevity regulating pathway, Longevity regulating pathway - multiple species, MicroRNAs in cancer, Neutrophil extracellular trap formation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Shigellosis, Spinocerebellar ataxia, Th17 cell differentiation, Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus, mTOR signaling pathway 💬[46] 2, 6, 13, 15, 17, 19, 21, 34, 35, 36, 46, 48, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 97, 98, 137, 157, 158, 192, 193, 222, 227, 256, 277, 278, 279, 280, 281, 283, 285, 300, 331 💬
37 THK-5351 [1] THK-5351---[5] 5, 6, 7, 17, 127 💬
38 Tolterodine [1] Tolterodine[2] Tolterodine ,
Tolterodine tartrate 💬 		[1] CHRM3 💬 [12] Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction 💬[1] 17 💬
39 Trimethaphan [1] Trimethaphan---[1] 17 💬
40 Ubiquinol [1] Ubiquinol---[3] 6, 8, 17 💬
41 Verdiperstat [1] Verdiperstat[1] Verdiperstat 💬 [1] MPO 💬 [5] Acute myeloid leukemia, Drug metabolism - other enzymes, Neutrophil extracellular trap formation, Phagosome, Transcriptional misregulation in cancer 💬[2] 17, 127 💬
42 Water [1] Water[1] Water 💬 --[28] 2, 5, 6, 13, 17, 19, 22, 35, 46, 51, 53, 56, 57, 63, 64, 66, 67, 72, 85, 96, 97, 206, 225, 226, 230, 274, 278, 299 💬
43 YA-101 [1] YA-101---[1] 17 💬
44 Zoledronic acid [3] Zoledronate; Zoledronic acid; Zoledronic acid monohydrate[5] Zoledronic acid ,
Zoledronate disodium ,
Zoledronate trisodium ,
Zoledronic acid ,
Zoledronic acid hemipentahydrate 💬 		[1] FDPS 💬 [3] Human T-cell leukemia virus 1 infection, Influenza A, Terpenoid backbone biosynthesis 💬[16] 5, 6, 13, 17, 46, 65, 75, 77, 93, 95, 96, 97, 270, 274, 299, 333 💬