Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank Drug (Description in trials) KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1 Ammonia [1] Ammonia[1] Ammonia solution, strong 💬 --[6] 6, 17, 86, 88, 251, 296 💬
2 Ampreloxetine [1] Ampreloxetine[1] Ampreloxetine 💬 [2] SLC6A2,
SLC6A4 💬 		[3] Neuroactive ligand signaling, Serotonergic synapse, Synaptic vesicle cycle 💬[2] 6, 17 💬
3 ATH434 [1] ATH434---[1] 17 💬
4 Atomoxetine [1] Atomoxetine[2] Atomoxetine hydrochloride ,
Atomoxetine 💬 		[1] SLC6A2 💬 [2] Neuroactive ligand signaling, Synaptic vesicle cycle 💬[4] 6, 8, 13, 17 💬
5 Botulinum toxin type A [5] Botulinum toxin A; BOTULINUM TOXIN TYPE A; IncobotulinumtoxinA; Onabotulinumtoxin A; OnabotulinumtoxinA[4] Botulinum toxin type A ,
OnabotulinumtoxinA ,
AbobotulinumtoxinA ,
Incobotulinumtoxin A 💬 		[1] SNAP25 💬 [2] Insulin secretion, Synaptic vesicle cycle 💬[13] 2, 5, 6, 7, 13, 15, 17, 47, 70, 113, 149, 171, 226 💬
6 BQ-123 [0] ---[1] 17 💬
7 Butylphthalide [2] 3-N-butylphthalide; Butylphthalide---[4] 2, 6, 17, 22 💬
8 Captopril [1] Captopril[1] Captopril 💬 [1] ACE 💬 [6] Chagas disease, Coronavirus disease, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬[3] 17, 57, 86 💬
9 Carbidopa [1] Carbidopa[1] Carbidopa 💬 [1] DDC 💬 [8] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬[7] 6, 13, 17, 90, 140, 164, 201 💬
10 Domperidone [1] Domperidone[2] Domperidone ,
Domperidone maleate 💬 		[1] DRD2 💬 [10] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[5] 6, 13, 17, 51, 230 💬
11 Dopamine [1] Dopamine[2] Dopamine hydrochloride ,
Dopamine 💬 		[5] DRD1,
DRD2,
DRD3,
DRD4,
DRD5 💬 		[13] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[5] 6, 7, 17, 74, 77 💬
12 Droxidopa [2] Droxidopa; L-DOPS[1] Droxidopa 💬 [9] ADRA1A,
ADRA1B,
ADRA1D,
ADRA2A,
ADRA2B,
ADRA2C,
ADRB1,
ADRB2,
ADRB3 💬 		[16] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[5] 5, 6, 17, 169, 170 💬
13 Emeramide [1] Emeramide---[2] 5, 17 💬
14 Entacapone [2] ENTACAPONA; ENTACAPONE[1] Entacapone 💬 [1] COMT 💬 [3] Dopaminergic synapse, Steroid hormone biosynthesis, Tyrosine metabolism 💬[2] 6, 17 💬
15 Exenatide [1] Exenatide[1] Exenatide 💬 [1] GLP1R 💬 [4] Hormone signaling, Insulin secretion, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[6] 6, 17, 72, 78, 193, 233 💬
16 Exidavnemab [1] Exidavnemab---[2] 6, 17 💬
17 Fipamezole [1] Fipamezole---[2] 6, 17 💬
18 Fludrocortisone [1] Fludrocortisone[2] Fludrocortisone acetate ,
Fludrocortisone 💬 		[1] NR3C2 💬 [1] Aldosterone-regulated sodium reabsorption 💬[3] 6, 17, 81 💬
19 Flumazenil [1] Flumazenil[1] Flumazenil 💬 [16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬 		[9] Cadherin signaling, GABAergic synapse, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[5] 6, 13, 17, 18, 206 💬
20 Fluoxetine [3] Fluoxetine; FLUOXETINE HYDROCHLORIDE; Fluoxétine[2] Fluoxetine ,
Fluoxetine hydrochloride 💬 		[1] SLC6A4 💬 [3] Neuroactive ligand signaling, Serotonergic synapse, Synaptic vesicle cycle 💬[3] 13, 17, 86 💬
21 Flutemetamol [1] Flutemetamol---[6] 2, 5, 6, 7, 17, 127 💬
22 Foralumab [1] Foralumab---[3] 13, 17, 96 💬
23 Gold [1] Gold---[71] 2, 5, 6, 11, 13, 17, 19, 21, 22, 28, 34, 35, 46, 49, 50, 53, 54, 56, 57, 58, 60, 63, 64, 65, 66, 68, 71, 75, 76, 77, 79, 84, 85, 86, 88, 91, 93, 95, 96, 97, 98, 107, 113, 127, 137, 158, 162, 167, 171, 193, 206, 215, 218, 222, 223, 224, 226, 227, 228, 230, 235, 271, 291, 294, 296, 298, 299, 310, 318, 331, 340 💬
24 Green tea leaf [1] GREEN TEA LEAF[1] Green tea leaf 💬 --[1] 17 💬
25 Hydrogen [1] Hydrogen---[8] 5, 6, 13, 17, 83, 97, 226, 238 💬
26 Idebenone [1] Idebenone[1] Idebenone 💬 --[9] 6, 8, 13, 17, 18, 21, 113, 115, 302 💬
27 Inosine [1] Inosine[1] Inosine 💬 --[5] 2, 6, 13, 17, 122 💬
28 Levodopa [2] L-DOPA; Levodopa[1] Levodopa 💬 [5] DRD1,
DRD2,
DRD3,
DRD4,
DRD5 💬 		[13] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[8] 5, 6, 17, 90, 120, 140, 164, 201 💬
29 Lithium carbonate [1] Lithium Carbonate[1] Lithium carbonate 💬 --[6] 2, 13, 17, 18, 127, 310 💬
30 Losartan [2] Losartan; LOSARTAN POTASSIUM[2] Losartan potassium ,
Losartan 💬 		[1] AGTR1 💬 [17] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Hormone signaling, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[20] 17, 19, 36, 46, 57, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 223, 299 💬
31 Metoprolol [2] Metoprolol; METOPROLOL SUCCINATE[4] Metoprolol tartrate ,
Metoprolol succinate ,
Metoprolol ,
Metoprolol fumarate 💬 		[1] ADRB1 💬 [13] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[6] 17, 57, 58, 113, 193, 226 💬
32 Midodrine [2] Midodrine; MIDODRINE HYDROCHLORIDE[2] Midodrine hydrochloride ,
Midodrine 💬 		[3] ADRA1A,
ADRA1B,
ADRA1D 💬 		[9] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[3] 6, 17, 58 💬
33 Nebivolol [1] Nebivolol[2] Nebivolol ,
Nebivolol hydrochloride 💬 		[1] ADRB1 💬 [13] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[4] 17, 85, 113, 167 💬
34 Nicotinamide [2] Niacinamide; Nicotinamide[1] Niacinamide 💬 --[19] 2, 5, 6, 7, 8, 17, 18, 21, 46, 49, 60, 63, 65, 85, 97, 107, 162, 191, 302 💬
35 Nicotinamide riboside [2] Nicotinamide riboside; Nicotinamide Riboside Chloride---[14] 2, 5, 6, 7, 8, 17, 18, 21, 49, 60, 65, 85, 97, 191 💬
36 Nitrogen [1] Nitrogen[1] Nitrogen 💬 --[6] 5, 6, 17, 171, 211, 299 💬
37 Pseudoephedrine [1] Pseudoephedrine[4] Pseudoephedrine hydrochloride ,
Pseudoephedrine polistirex ,
Pseudoephedrine sulfate ,
Pseudoephedrine 💬 		[9] ADRA1A,
ADRA1B,
ADRA1D,
ADRA2A,
ADRA2B,
ADRA2C,
ADRB1,
ADRB2,
ADRB3 💬 		[16] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 17 💬
38 Raclopride [1] Raclopride---[4] 5, 6, 7, 17 💬
39 Rasagiline [2] RASAGILINE; RASAGILINE MESYLATE[3] Rasagiline mesylate ,
Rasagiline ,
Rasagiline tartrate 💬 		[1] MAOB 💬 [13] Alcoholism, Amphetamine addiction, Arginine and proline metabolism, Cocaine addiction, Dopaminergic synapse, Drug metabolism - cytochrome P450, Glycine, serine and threonine metabolism, Histidine metabolism, Parkinson disease, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬[4] 2, 5, 6, 17 💬
40 Riluzole [1] Riluzole[1] Riluzole 💬 [14] GRIA1,
GRIA2,
GRIA3,
GRIA4,
GRIK1,
GRIK2,
GRIK3,
GRIK4,
GRIK5,
GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬 		[24] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term depression, Long-term potentiation, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Retrograde endocannabinoid signaling, Spinocerebellar ataxia, Systemic lupus erythematosus, Transcriptional misregulation in cancer, cAMP signaling pathway 💬[9] 2, 3, 5, 8, 13, 17, 18, 203, 206 💬
41 Safinamide [2] Safinamida; SAFINAMIDE[2] Safinamide ,
Safinamide mesylate 💬 		[1] MAOB 💬 [13] Alcoholism, Amphetamine addiction, Arginine and proline metabolism, Cocaine addiction, Dopaminergic synapse, Drug metabolism - cytochrome P450, Glycine, serine and threonine metabolism, Histidine metabolism, Parkinson disease, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬[2] 6, 17 💬
42 Sirolimus [2] Rapamycin; Sirolimus[1] Sirolimus 💬 [1] MTOR 💬 [52] AMPK signaling pathway, Acute myeloid leukemia, Adipocytokine signaling pathway, Alzheimer disease, Amyotrophic lateral sclerosis, Apelin signaling pathway, Autophagy - animal, Autophagy - other, Breast cancer, Cellular senescence, Central carbon metabolism in cancer, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Diabetic cardiomyopathy, ErbB signaling pathway, Gastric cancer, Glioma, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatocellular carcinoma, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Huntington disease, Insulin resistance, Insulin signaling pathway, Integrated stress response (ISR) signaling pathway, Integrin signaling, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Longevity regulating pathway, Longevity regulating pathway - multiple species, Lysosome biogenesis, MicroRNAs in cancer, Neutrophil extracellular trap formation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Shigellosis, Spinocerebellar ataxia, Th17 cell differentiation, Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus, mTOR signaling pathway 💬[46] 6, 13, 15, 17, 19, 21, 34, 35, 36, 46, 48, 49, 51, 54, 57, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 97, 98, 111, 127, 137, 157, 158, 192, 222, 223, 227, 277, 278, 279, 280, 281, 283, 285, 300, 331 💬
43 Tea leaf [1] Tea leaf---[1] 17 💬
44 THK-5351 [1] THK-5351---[5] 5, 6, 7, 17, 127 💬
45 Tolterodine [1] Tolterodine[2] Tolterodine ,
Tolterodine tartrate 💬 		[1] CHRM3 💬 [12] Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction 💬[2] 17, 53 💬
46 Trimethaphan [1] Trimethaphan---[1] 17 💬
47 Ubiquinol [1] Ubiquinol---[4] 6, 8, 17, 57 💬
48 Verdiperstat [1] Verdiperstat[1] Verdiperstat 💬 [1] MPO 💬 [5] Acute myeloid leukemia, Drug metabolism - other enzymes, Neutrophil extracellular trap formation, Phagocytosis, Transcriptional misregulation in cancer 💬[3] 2, 17, 127 💬
49 Water [1] Water[1] Water 💬 --[36] 2, 3, 5, 6, 13, 17, 19, 22, 35, 46, 49, 51, 53, 56, 57, 62, 63, 64, 65, 66, 67, 70, 72, 85, 86, 96, 97, 206, 215, 225, 226, 230, 240, 274, 278, 299 💬
50 YA-101 [1] YA-101---[1] 17 💬
51 Zoledronic acid [2] Zoledronic Acid; ZOLEDRONIC ACID MONOHYDRATE[5] Zoledronic acid ,
Zoledronate disodium ,
Zoledronate trisodium ,
Zoledronic acid ,
Zoledronic acid hemipentahydrate 💬 		[1] FDPS 💬 [3] Human T-cell leukemia virus 1 infection, Influenza A, Terpenoid backbone biosynthesis 💬[16] 5, 6, 13, 17, 46, 75, 77, 93, 95, 96, 97, 270, 274, 282, 299, 333 💬