Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank Drug (Description in trials) KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1 Abatacept [1] Abatacept[1] Abatacept 💬 [2] CD80,
CD86 💬 		[13] Allograft rejection, Autoimmune thyroid disease, Cell adhesion molecules, Graft-versus-host disease, Intestinal immune network for IgA production, Kaposi sarcoma-associated herpesvirus infection, Rheumatoid arthritis, Systemic lupus erythematosus, Toll-like receptor signaling pathway, Transcriptional misregulation in cancer, Type I diabetes mellitus, Viral myocarditis, Virion - Adenovirus 💬[27] 2, 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
2 Alkaline Phosphatase [1] Alkaline phosphatase---[3] 46, 93, 97 💬
3 Atorvastatin [2] Atorvastatin; Atorvastatin calcium[2] Atorvastatin calcium ,
Atorvastatin 💬 		[1] HMGCR 💬 [3] AMPK signaling pathway, Bile secretion, Terpenoid backbone biosynthesis 💬[20] 13, 22, 46, 49, 51, 58, 63, 67, 79, 84, 88, 93, 96, 97, 160, 225, 265, 271, 297, 299 💬
4 Baricitinib [1] Baricitinib[1] Baricitinib 💬 [2] JAK1,
JAK2 💬 		[37] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease - COVID-19, Efferocytosis, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Hormone signaling, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Necroptosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬[21] 2, 13, 40, 41, 46, 49, 50, 51, 53, 54, 84, 93, 107, 135, 162, 265, 268, 269, 300, 325, 345 💬
5 Bezafibrate [1] Bezafibrate[1] Bezafibrate 💬 [1] NR1C1 💬 [10] Adipocytokine signaling pathway, Alcoholic liver disease, Chemical carcinogenesis - receptor activation, Diabetic cardiomyopathy, Glucagon signaling pathway, Hepatitis C, Insulin resistance, Non-alcoholic fatty liver disease, PPAR signaling pathway, cAMP signaling pathway 💬[8] 20, 93, 94, 160, 296, 316, 324, 344 💬
6 Budesonide [1] Budesonide[1] Budesonide 💬 [1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[9] 66, 93, 94, 95, 96, 97, 98, 228, 299 💬
7 Calcium [2] Calcio; Calcium---[24] 6, 13, 19, 46, 49, 51, 53, 68, 75, 84, 93, 95, 96, 97, 156, 186, 214, 215, 222, 235, 271, 274, 298, 299 💬
8 Cilofexor [1] Cilofexor---[2] 93, 94 💬
9 Colchicine [1] Colchicine[1] Colchicine 💬 [9] TUBB,
TUBB,
TUBB,
TUBB,
TUBB,
TUBB,
TUBB,
TUBB,
TUBB 💬 		[11] Alzheimer disease, Amyotrophic lateral sclerosis, Gap junction, Huntington disease, Motor proteins, Parkinson disease, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Phagosome, Prion disease, Salmonella infection 💬[9] 2, 42, 46, 50, 56, 93, 97, 210, 266 💬
10 Cyclophosphamide [5] Ciclofosfamida; Ciclofosfamide; Cyclophosphamid; Cyclophosphamide; Cyclophosphamide monohydrate[2] Cyclophosphamide ,
Cyclophosphamide 💬 		--[46] 11, 13, 14, 16, 19, 20, 26, 28, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 56, 60, 62, 65, 66, 84, 93, 96, 162, 164, 172, 205, 220, 221, 222, 224, 256, 265, 274, 283, 284, 285, 288, 326, 331 💬
11 Cyclosporine [6] Ciclosporin; Ciclosporina; Ciclosporine; Cyclosporin; Cyclosporin A; Cyclosporine[1] Cyclosporine 💬 [5] PPP3C,
PPP3C,
PPP3C,
PPP3R,
PPP3R 💬 		[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬[42] 11, 19, 20, 26, 28, 36, 40, 41, 42, 45, 46, 49, 50, 53, 54, 55, 56, 58, 60, 61, 62, 63, 64, 65, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
12 Denosumab [1] Denosumab[1] Denosumab 💬 [1] TNFSF11 💬 [8] Breast cancer, Chemical carcinogenesis - receptor activation, Cytokine-cytokine receptor interaction, NF-kappa B signaling pathway, Osteoclast differentiation, Parathyroid hormone synthesis, secretion and action, Prolactin signaling pathway, Rheumatoid arthritis 💬[10] 46, 50, 70, 75, 77, 93, 95, 96, 274, 299 💬
13 Elafibranor [1] Elafibranor[1] Elafibranor 💬 [1] NR1C1 💬 [10] Adipocytokine signaling pathway, Alcoholic liver disease, Chemical carcinogenesis - receptor activation, Diabetic cardiomyopathy, Glucagon signaling pathway, Hepatitis C, Insulin resistance, Non-alcoholic fatty liver disease, PPAR signaling pathway, cAMP signaling pathway 💬[2] 93, 94 💬
14 Emtricitabine [1] Emtricitabine[1] Emtricitabine 💬 --[4] 13, 93, 265, 325 💬
15 Ezetimibe [1] Ezetimibe[1] Ezetimibe 💬 [1] NPC1L1 💬 [1] Fat digestion and absorption 💬[5] 49, 79, 93, 149, 260 💬
16 Fecal microbiota [1] Fecal microbiota---[12] 2, 6, 13, 49, 63, 66, 93, 94, 96, 97, 99, 271 💬
17 Fenofibrate [1] Fenofibrate[1] Fenofibrate 💬 [1] NR1C1 💬 [10] Adipocytokine signaling pathway, Alcoholic liver disease, Chemical carcinogenesis - receptor activation, Diabetic cardiomyopathy, Glucagon signaling pathway, Hepatitis C, Insulin resistance, Non-alcoholic fatty liver disease, PPAR signaling pathway, cAMP signaling pathway 💬[6] 8, 79, 93, 94, 97, 265 💬
18 Golexanolone [1] Golexanolone---[1] 93 💬
19 Hesperidin [1] Hesperidin[1] Hesperidin 💬 --[1] 93 💬
20 Linerixibat [1] Linerixibat[1] Linerixibat 💬 [1] SLC10A2 💬 [1] Bile secretion 💬[1] 93 💬
21 Methotrexate [5] Methotrexat; Methotrexate; Methotrexate sodium; Metotrexato; Méthotrexate[2] Methotrexate ,
Methotrexate sodium 💬 		[2] DHFR,
DHFR 💬 		[3] Folate biosynthesis, Folate transport and metabolism, One carbon pool by folate 💬[39] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 54, 55, 56, 60, 62, 65, 84, 85, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 284, 285, 286, 326, 331 💬
22 Methylprednisolone [3] Methylprednisolon; Methylprednisolone; Methylprednisolone acetate[2] Methylprednisolone ,
Methylprednisolone acetate 💬 		[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[48] 2, 6, 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 95, 96, 97, 127, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296, 300 💬
23 Minodronic acid [2] Minodronate; Minodronic acid---[4] 6, 46, 93, 95 💬
24 Modafinil [1] Modafinil[1] Modafinil 💬 --[4] 6, 13, 49, 93 💬
25 Moexipril [1] Moexipril[2] Moexipril hydrochloride ,
Moexipril 💬 		[1] ACE 💬 [6] Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬[1] 93 💬
26 Mycophenolate mofetil [1] Mycophenolate mofetil[2] Mycophenolate mofetil ,
Mycophenolate mofetil hydrochloride 💬 		[2] IMPDH,
IMPDH 💬 		[2] Drug metabolism - other enzymes, Purine metabolism 💬[34] 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 93, 95, 96, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬
27 Mycophenolic acid [5] Acido micofenolico; Micofenolico acido; Mycophenolate; Mycophenolate sodium; Mycophenolic acid[2] Mycophenolate sodium ,
Mycophenolic acid 💬 		[2] IMPDH,
IMPDH 💬 		[2] Drug metabolism - other enzymes, Purine metabolism 💬[37] 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 84, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 💬
28 Nalmefene [1] Nalmefene[3] Nalmefene hydrochloride ,
Nalmefene ,
Nalmefene hydrochloride hydrate 💬 		[3] OPRD1,
OPRK1,
OPRM1 💬 		[7] Estrogen signaling pathway, Hormone signaling, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[2] 6, 93 💬
29 norUrsodeoxycholic acid [2] Norucholic acid; Norursodeoxycholic acid---[2] 93, 94 💬
30 Obeticholic acid [2] 6-ecdca; Obeticholic acid[1] Obeticholic acid 💬 [1] NR1H4 💬 [1] Bile secretion 💬[3] 93, 265, 296 💬
31 Pemafibrate [1] Pemafibrate[1] Pemafibrate 💬 [1] NR1C1 💬 [10] Adipocytokine signaling pathway, Alcoholic liver disease, Chemical carcinogenesis - receptor activation, Diabetic cardiomyopathy, Glucagon signaling pathway, Hepatitis C, Insulin resistance, Non-alcoholic fatty liver disease, PPAR signaling pathway, cAMP signaling pathway 💬[1] 93 💬
32 Pentoxifylline [1] Pentoxifylline[1] Pentoxifylline 💬 --[12] 6, 26, 56, 84, 93, 96, 97, 113, 220, 222, 296, 298 💬
33 Phenylbutyric acid [2] Phenylbutyrate; Sodium phenylbutyrate[1] Sodium phenylbutyrate 💬 --[10] 2, 3, 8, 15, 93, 94, 244, 251, 297, 338 💬
34 Prednisone [2] Prednisona; Prednisone[1] Prednisone 💬 [1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[54] 2, 11, 13, 14, 18, 19, 26, 28, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 60, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 90, 93, 95, 96, 97, 113, 145, 162, 164, 205, 222, 224, 228, 251, 269, 283, 285, 288, 299, 300, 303, 307, 331 💬
35 Pyridoxine [1] Pyridoxine[2] Pyridoxine hydrochloride ,
Pyridoxine 💬 		--[6] 6, 93, 97, 145, 234, 320 💬
36 Raltegravir [1] Raltegravir[2] Raltegravir ,
Raltegravir potassium 💬 		--[4] 13, 26, 93, 265 💬
37 Rifampin [2] Rifampicin; Rifampin[2] Rifampin ,
Rifampicin sodium 💬 		--[10] 6, 13, 17, 46, 84, 86, 93, 97, 299, 338 💬
38 Rifaximin [2] Rifaximin; Rifaximina[1] Rifaximin 💬 --[8] 6, 65, 93, 96, 97, 99, 296, 299 💬
39 Risedronic acid [3] Risedronate; Risedronate sodium; Risedronic acid[3] Risedronate sodium ,
Risedronic acid ,
Risedronate sodium monohydrate 💬 		[1] FDPS 💬 [3] Human T-cell leukemia virus 1 infection, Influenza A, Terpenoid backbone biosynthesis 💬[9] 46, 50, 66, 93, 95, 96, 107, 113, 274 💬
40 Rituximab [1] Rituximab[1] Rituximab 💬 [1] MS4A1 💬 [1] Hematopoietic cell lineage 💬[52] 11, 13, 14, 19, 26, 34, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 55, 56, 60, 61, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 162, 172, 220, 222, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331 💬
41 Saroglitazar [0] [2] Saroglitazar ,
Saroglitazar magnesium 💬 		[3] NR1C1,
NR1C2,
NR1C3 💬 		[22] AMPK signaling pathway, Acute myeloid leukemia, Adipocytokine signaling pathway, Alcoholic liver disease, Chemical carcinogenesis - receptor activation, Diabetic cardiomyopathy, Efferocytosis, Glucagon signaling pathway, Hepatitis C, Huntington disease, Insulin resistance, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer, Wnt signaling pathway, cAMP signaling pathway 💬[1] 93 💬
42 Seladelpar [1] Seladelpar[2] Seladelpar ,
Seladelpar lysine 💬 		[1] NR1C3 💬 [12] AMPK signaling pathway, Efferocytosis, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬[2] 93, 94 💬
43 Setanaxib [1] Setanaxib---[2] 93, 218 💬
44 Tauroursodeoxycholic acid [4] Tauroursodeoxycholic acid; Taurursodiol; Tudca; Ursodoxicoltaurine[1] Taurursodiol 💬 --[3] 2, 93, 299 💬
45 Tenofovir [1] Tenofovir[1] Tenofovir 💬 --[7] 2, 6, 13, 25, 93, 265, 325 💬
46 Tenofovir disoproxil [2] Tenofovir disoproxil; Tenofovir disoproxil fumarate[3] Tenofovir disoproxil fumarate ,
Tenofovir disoproxil phosphate ,
Tenofovir disoproxil maleate 💬 		--[3] 6, 93, 265 💬
47 Tetrathiomolybdate [1] Tetrathiomolybdate---[3] 85, 93, 171 💬
48 Thiamine [3] Thiamin; Thiamine; Vitamin B1[3] Thiamine hydrochloride ,
Thiamine mononitrate ,
Thiamine 💬 		--[6] 13, 93, 97, 145, 265, 302 💬
49 Tigecycline [1] Tigecycline[1] Tigecycline 💬 --[1] 93 💬
50 Tropifexor [1] Tropifexor[1] Tropifexor 💬 [1] NR1H4 💬 [1] Bile secretion 💬[1] 93 💬
51 Ursodeoxycholic acid [3] Udca; Ursodeoxycholic acid; Ursodiol[1] Ursodiol 💬 [1] NR1H4 💬 [1] Bile secretion 💬[14] 6, 8, 20, 46, 67, 84, 93, 94, 95, 96, 97, 234, 296, 299 💬
52 Ustekinumab [1] Ustekinumab[1] Ustekinumab 💬 [3] IL12A,
IL12B,
IL23A 💬 		[28] African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Amoebiasis, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Herpes simplex virus 1 infection, Inflammatory bowel disease, Influenza A, JAK-STAT signaling pathway, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, Malaria, Measles, Pathways in cancer, Pertussis, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus 💬[17] 37, 40, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
53 Vitamin D [2] Calciferol; Vitamin D---[22] 6, 13, 19, 41, 43, 44, 46, 49, 50, 68, 93, 95, 96, 97, 98, 179, 222, 228, 235, 274, 298, 299 💬
54 Volixibat [2] Volixibat; Volixibat potassium[2] Volixibat potassium ,
Volixibat 💬 		--[2] 93, 94 💬
55 Zoledronic acid [3] Zoledronate; Zoledronic acid; Zoledronic acid monohydrate[5] Zoledronic acid ,
Zoledronate disodium ,
Zoledronate trisodium ,
Zoledronic acid ,
Zoledronic acid hemipentahydrate 💬 		[1] FDPS 💬 [3] Human T-cell leukemia virus 1 infection, Influenza A, Terpenoid backbone biosynthesis 💬[16] 5, 6, 13, 17, 46, 65, 75, 77, 93, 95, 96, 97, 270, 274, 299, 333 💬