Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank Drug (Description in trials) KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1 Abatacept [1] Abatacept[1] Abatacept 💬 [2] CD80,
CD86 💬 		[14] Allograft rejection, Autoimmune thyroid disease, Cell adhesion molecule (CAM) interaction, Graft-versus-host disease, IgSF CAM signaling, Intestinal immune network for IgA production, Kaposi sarcoma-associated herpesvirus infection, Rheumatoid arthritis, Systemic lupus erythematosus, Toll-like receptor signaling pathway, Transcriptional misregulation in cancer, Type I diabetes mellitus, Viral myocarditis, Virion - Adenovirus 💬[28] 2, 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 223, 271, 284, 285, 300 💬
2 Alkaline Phosphatase [1] Alkaline Phosphatase---[4] 46, 93, 97, 172 💬
3 Atorvastatin [3] Atorvastatin; Atorvastatin calcium; Atorvastatina[2] Atorvastatin calcium ,
Atorvastatin 💬 		[1] HMGCR 💬 [3] AMPK signaling pathway, Bile secretion, Terpenoid backbone biosynthesis 💬[21] 13, 22, 46, 49, 51, 58, 63, 67, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 297, 299 💬
4 Azathioprine [2] Azathioprine; Azatioprina[2] Azathioprine ,
Azathioprine sodium 💬 		--[26] 6, 11, 13, 19, 35, 42, 43, 44, 45, 46, 49, 55, 57, 63, 65, 66, 84, 85, 93, 94, 95, 96, 97, 162, 223, 300 💬
5 Baricitinib [1] Baricitinib[1] Baricitinib 💬 [2] JAK1,
JAK2 💬 		[37] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease, Efferocytosis, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Hormone signaling, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Necroptosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬[24] 2, 13, 40, 41, 46, 49, 50, 51, 53, 54, 56, 63, 65, 84, 93, 107, 135, 162, 265, 268, 269, 300, 325, 345 💬
6 Bezafibrate [1] Bezafibrate[1] Bezafibrate 💬 [1] PPARA 💬 [10] Adipocytokine signaling pathway, Alcoholic liver disease, Chemical carcinogenesis - receptor activation, Diabetic cardiomyopathy, Glucagon signaling pathway, Hepatitis C, Insulin resistance, Non-alcoholic fatty liver disease, PPAR signaling pathway, cAMP signaling pathway 💬[8] 20, 93, 94, 160, 296, 316, 324, 344 💬
7 Budesonide [1] BUDESONIDE[1] Budesonide 💬 [1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[10] 66, 93, 94, 95, 96, 97, 98, 223, 228, 299 💬
8 Calcium [1] Calcium---[39] 2, 3, 6, 13, 15, 19, 46, 48, 49, 51, 53, 56, 62, 67, 68, 71, 74, 75, 79, 84, 90, 93, 94, 95, 96, 97, 156, 186, 214, 215, 222, 224, 235, 256, 265, 271, 274, 298, 299 💬
9 Choline [2] Choline; Choline Chloride[1] Choline 💬 --[4] 93, 171, 193, 299 💬
10 Cilofexor [1] Cilofexor---[2] 93, 94 💬
11 Colchicine [2] COLCHICINA; Colchicine[1] Colchicine 💬 [9] TUBB,
TUBB1,
TUBB2A,
TUBB2B,
TUBB3,
TUBB4A,
TUBB4B,
TUBB6,
TUBB8 💬 		[12] Alzheimer disease, Amyotrophic lateral sclerosis, Gap junction, Huntington disease, IgSF CAM signaling, Motor proteins, Parkinson disease, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Phagocytosis, Prion disease, Salmonella infection 💬[9] 2, 42, 46, 50, 56, 93, 97, 210, 266 💬
12 Cyclophosphamide [5] Ciclofosfamida; CICLOFOSFAMIDE; Cyclophosphamid; Cyclophosphamide; CYCLOPHOSPHAMIDE MONOHYDRATE[2] Cyclophosphamide ,
Cyclophosphamide 💬 		--[50] 11, 13, 14, 16, 19, 20, 26, 28, 34, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 56, 60, 61, 62, 63, 65, 66, 84, 93, 96, 162, 164, 172, 205, 221, 222, 223, 224, 256, 265, 274, 283, 284, 285, 288, 326, 331 💬
13 Denosumab [1] Denosumab[1] Denosumab 💬 [1] TNFSF11 💬 [8] Breast cancer, Chemical carcinogenesis - receptor activation, Cytokine-cytokine receptor interaction, NF-kappa B signaling pathway, Osteoclast differentiation, Parathyroid hormone synthesis, secretion and action, Prolactin signaling pathway, Rheumatoid arthritis 💬[11] 46, 50, 70, 75, 77, 93, 95, 96, 223, 274, 299 💬
14 Elafibranor [1] ELAFIBRANOR[1] Elafibranor 💬 [1] PPARA 💬 [10] Adipocytokine signaling pathway, Alcoholic liver disease, Chemical carcinogenesis - receptor activation, Diabetic cardiomyopathy, Glucagon signaling pathway, Hepatitis C, Insulin resistance, Non-alcoholic fatty liver disease, PPAR signaling pathway, cAMP signaling pathway 💬[2] 93, 94 💬
15 Emtricitabine [1] Emtricitabine[1] Emtricitabine 💬 --[5] 13, 25, 93, 265, 325 💬
16 Ezetimibe [1] Ezetimibe[1] Ezetimibe 💬 [1] NPC1L1 💬 [1] Fat digestion and absorption 💬[5] 49, 79, 93, 149, 260 💬
17 Fecal microbiota [3] Fecal Microbial Transplantation; Fecal microbiota; Fecal microbiota transplantation---[14] 2, 6, 13, 49, 63, 66, 93, 94, 96, 97, 99, 222, 271, 298 💬
18 Fenofibrate [1] Fenofibrate[1] Fenofibrate 💬 [1] PPARA 💬 [10] Adipocytokine signaling pathway, Alcoholic liver disease, Chemical carcinogenesis - receptor activation, Diabetic cardiomyopathy, Glucagon signaling pathway, Hepatitis C, Insulin resistance, Non-alcoholic fatty liver disease, PPAR signaling pathway, cAMP signaling pathway 💬[6] 8, 79, 93, 94, 97, 265 💬
19 Gold [1] Gold---[71] 2, 5, 6, 11, 13, 17, 19, 21, 22, 28, 34, 35, 46, 49, 50, 53, 54, 56, 57, 58, 60, 63, 64, 65, 66, 68, 71, 75, 76, 77, 79, 84, 85, 86, 88, 91, 93, 95, 96, 97, 98, 107, 113, 127, 137, 158, 162, 167, 171, 193, 206, 215, 218, 222, 223, 224, 226, 227, 228, 230, 235, 271, 291, 294, 296, 298, 299, 310, 318, 331, 340 💬
20 Golexanolone [1] GOLEXANOLONE---[1] 93 💬
21 Hesperidin [1] Hesperidin[1] Hesperidin 💬 --[3] 13, 46, 93 💬
22 Linerixibat [1] Linerixibat[1] Linerixibat 💬 [1] SLC10A2 💬 [1] Bile secretion 💬[1] 93 💬
23 Magnesium [2] MAGNESIO; Magnesium---[23] 3, 6, 11, 13, 15, 46, 64, 70, 71, 93, 97, 113, 166, 225, 234, 235, 256, 284, 291, 296, 297, 298, 340 💬
24 Methionine [2] L-methionine; Methionine[1] Methionine 💬 --[9] 34, 75, 84, 93, 94, 229, 298, 300, 337 💬
25 Methotrexate [5] Methotrexat; Methotrexate; METHOTREXATE SODIUM; Methylaminopterin; METOTREXATO[2] Methotrexate ,
Methotrexate sodium 💬 		[2] DHFR,
DHFR2 💬 		[3] Folate biosynthesis, Folate transport and metabolism, One carbon pool by folate 💬[41] 11, 13, 14, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 54, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 223, 240, 256, 270, 271, 284, 285, 286, 326, 331 💬
26 Methylprednisolone [3] Methylprednisolon; METHYLPREDNISOLONE; METHYLPREDNISOLONE ACETATE[2] Methylprednisolone ,
Methylprednisolone acetate 💬 		[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[51] 2, 6, 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 95, 96, 97, 111, 127, 145, 162, 164, 211, 222, 223, 224, 271, 283, 284, 285, 296, 300 💬
27 Minodronic acid [1] Minodronic acid---[4] 6, 46, 93, 95 💬
28 Modafinil [1] Modafinil[1] Modafinil 💬 --[6] 6, 13, 49, 93, 96, 97 💬
29 Moexipril [1] Moexipril[2] Moexipril hydrochloride ,
Moexipril 💬 		[1] ACE 💬 [6] Chagas disease, Coronavirus disease, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬[1] 93 💬
30 Mycophenolate mofetil [1] Mycophenolate mofetil[2] Mycophenolate mofetil ,
Mycophenolate mofetil hydrochloride 💬 		[2] IMPDH1,
IMPDH2 💬 		[2] Drug metabolism - other enzymes, Purine metabolism 💬[38] 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 46, 49, 51, 53, 57, 60, 61, 62, 63, 65, 66, 93, 95, 96, 118, 162, 164, 222, 223, 224, 226, 234, 283, 284, 285, 300 💬
31 Nalmefene [1] Nalmefene[3] Nalmefene hydrochloride ,
Nalmefene ,
Nalmefene hydrochloride hydrate 💬 		[3] OPRD1,
OPRK1,
OPRM1 💬 		[7] Estrogen signaling pathway, Hormone signaling, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[2] 6, 93 💬
32 Obeticholic acid [1] Obeticholic Acid[1] Obeticholic acid 💬 [1] NR1H4 💬 [1] Bile secretion 💬[3] 93, 265, 296 💬
33 Pemafibrate [1] Pemafibrate[1] Pemafibrate 💬 [1] PPARA 💬 [10] Adipocytokine signaling pathway, Alcoholic liver disease, Chemical carcinogenesis - receptor activation, Diabetic cardiomyopathy, Glucagon signaling pathway, Hepatitis C, Insulin resistance, Non-alcoholic fatty liver disease, PPAR signaling pathway, cAMP signaling pathway 💬[2] 67, 93 💬
34 Pentoxifylline [1] Pentoxifylline[1] Pentoxifylline 💬 --[13] 6, 26, 46, 56, 84, 93, 96, 97, 113, 222, 223, 296, 298 💬
35 Potassium [1] Potassium[1] Potassium 💬 --[17] 36, 46, 57, 58, 66, 67, 88, 93, 94, 97, 98, 115, 167, 179, 215, 223, 235 💬
36 Prednisone [2] Prednisona; Prednisone[1] Prednisone 💬 [1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[58] 2, 11, 13, 14, 18, 19, 26, 28, 35, 40, 41, 42, 43, 44, 45, 46, 48, 49, 50, 51, 53, 60, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 90, 93, 95, 96, 97, 113, 127, 145, 162, 164, 205, 222, 223, 224, 228, 251, 269, 283, 284, 285, 288, 299, 300, 303, 307, 331 💬
37 Pyridoxine [2] Pyridoxine; Vitamin B 6[2] Pyridoxine hydrochloride ,
Pyridoxine 💬 		--[5] 49, 93, 145, 234, 320 💬
38 Raltegravir [1] Raltegravir[2] Raltegravir ,
Raltegravir potassium 💬 		--[4] 13, 26, 93, 265 💬
39 Rifaximin [2] Rifaximin; RIFAXIMINA[1] Rifaximin 💬 --[8] 6, 65, 93, 96, 97, 99, 296, 299 💬
40 Risedronic acid [3] Risedronate; RISEDRONATE SODIUM; Risedronic acid[3] Risedronate sodium ,
Risedronic acid ,
Risedronate sodium monohydrate 💬 		[1] FDPS 💬 [3] Human T-cell leukemia virus 1 infection, Influenza A, Terpenoid backbone biosynthesis 💬[7] 46, 50, 93, 95, 107, 113, 274 💬
41 Rituximab [1] Rituximab[1] Rituximab 💬 [1] MS4A1 💬 [1] Hematopoietic cell lineage 💬[54] 11, 13, 14, 19, 26, 34, 35, 36, 40, 41, 42, 43, 44, 45, 46, 48, 49, 50, 51, 52, 53, 55, 56, 60, 61, 62, 63, 64, 65, 66, 83, 84, 85, 86, 88, 93, 94, 96, 97, 162, 172, 222, 223, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331 💬
42 Saroglitazar [2] Saroglitazar; SAROGLITAZAR MAGNESIUM[2] Saroglitazar ,
Saroglitazar magnesium 💬 		[3] PPARA,
PPARD,
PPARG 💬 		[22] AMPK signaling pathway, Acute myeloid leukemia, Adipocytokine signaling pathway, Alcoholic liver disease, Chemical carcinogenesis - receptor activation, Diabetic cardiomyopathy, Efferocytosis, Glucagon signaling pathway, Hepatitis C, Huntington disease, Insulin resistance, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer, Wnt signaling pathway, cAMP signaling pathway 💬[1] 93 💬
43 Seladelpar [1] SELADELPAR[2] Seladelpar ,
Seladelpar lysine 💬 		[1] PPARG 💬 [12] AMPK signaling pathway, Efferocytosis, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬[2] 93, 94 💬
44 Setanaxib [1] Setanaxib---[2] 93, 218 💬
45 Tauroursodeoxycholic acid [3] Tauroursodeoxycholic acid; Taurursodiol; Ursodoxicoltaurine[1] Taurursodiol 💬 --[5] 2, 28, 93, 299, 302 💬
46 Tenofovir [1] Tenofovir[1] Tenofovir 💬 --[8] 2, 6, 13, 25, 26, 93, 265, 325 💬
47 Tenofovir disoproxil [2] Tenofovir disoproxil; Tenofovir Disoproxil Fumarate[3] Tenofovir disoproxil fumarate ,
Tenofovir disoproxil phosphate ,
Tenofovir disoproxil maleate 💬 		--[3] 6, 93, 265 💬
48 Tetrathiomolybdate [1] Tetrathiomolybdate---[3] 85, 93, 171 💬
49 Thiamine [1] Thiamine[3] Thiamine hydrochloride ,
Thiamine mononitrate ,
Thiamine 💬 		--[5] 8, 13, 93, 265, 340 💬
50 Tigecycline [1] Tigecycline[1] Tigecycline 💬 --[2] 93, 299 💬
51 Tropifexor [1] Tropifexor[1] Tropifexor 💬 [1] NR1H4 💬 [1] Bile secretion 💬[1] 93 💬
52 Ursodeoxycholic acid [3] UDCA; Ursodeoxycholic acid; Ursodiol[1] Ursodiol 💬 [1] NR1H4 💬 [1] Bile secretion 💬[10] 6, 46, 67, 84, 93, 94, 95, 96, 97, 296 💬
53 Ustekinumab [1] USTEKINUMAB[1] Ustekinumab 💬 [3] IL12A,
IL12B,
IL23A 💬 		[28] African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Amoebiasis, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease, Cytokine-cytokine receptor interaction, Herpes simplex virus 1 infection, Inflammatory bowel disease, Influenza A, JAK-STAT signaling pathway, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, Malaria, Measles, Pathways in cancer, Pertussis, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus 💬[17] 37, 40, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
54 Vitamin D [1] Vitamin D---[26] 3, 6, 13, 15, 19, 41, 43, 44, 46, 49, 50, 68, 74, 93, 95, 96, 97, 98, 179, 222, 228, 235, 256, 274, 298, 299 💬
55 Volixibat [2] VOLIXIBAT; Volixibat potassium[2] Volixibat potassium ,
Volixibat 💬 		--[2] 93, 94 💬
56 Zoledronic acid [2] ZOLEDRONIC ACID; ZOLEDRONIC ACID MONOHYDRATE[5] Zoledronic acid ,
Zoledronate disodium ,
Zoledronate trisodium ,
Zoledronic acid ,
Zoledronic acid hemipentahydrate 💬 		[1] FDPS 💬 [3] Human T-cell leukemia virus 1 infection, Influenza A, Terpenoid backbone biosynthesis 💬[16] 5, 6, 13, 17, 46, 75, 77, 93, 95, 96, 97, 270, 274, 282, 299, 333 💬