Drug Description in Trials / DrugBank / KEGG DRUG


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No. DrugBank Drug (Description in trials) KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1 Acazicolcept
(Fc fusion protein of a human inducible T cell costimulator ligand variant immunoglobulin domain designed to inhibit simultaneously the CD28 and ICOS inflammation pathways)
[1] Acazicolcept[1] Acazicolcept 💬 [2] CD28,
ICOS 💬
[13] Allograft rejection, Autoimmune thyroid disease, Cell adhesion molecules, Graft-versus-host disease, Intestinal immune network for IgA production, Measles, PD-L1 expression and PD-1 checkpoint pathway in cancer, Primary immunodeficiency, Rheumatoid arthritis, Systemic lupus erythematosus, T cell receptor signaling pathway, Type I diabetes mellitus, Viral myocarditis 💬[1] 49 💬
2 AMT-101
(Recombinant human interleukin-10 fusion protein)
[1] AMT-101---[2] 46, 97 💬
3 Batiraxcept
(Axl fc fusion protein avb-s6-500)
[1] AVB-S6-500[1] Batiraxcept 💬 [1] AXL 💬 [1] Efferocytosis 💬[1] 66 💬
4 Efavaleukin alfa
(Fc il-2 mutein fusion protein)
[1] Efavaleukin alfa[1] Efavaleukin alfa 💬 --[2] 49, 97 💬
5 Efzofitimod
(Human IgG1Fc- iMod domain of human HARS fusion protein)
[1] Efzofitimod[1] Efzofitimod 💬 [2] HARS,
HARS 💬
[1] Aminoacyl-tRNA biosynthesis 💬[2] 51, 84 💬
6 Froniglutide
(Glucagon like peptide-1 Elastin like peptide-120 fusion protein)
[1] Froniglutide---[1] 50 💬
7 Goflikicept
(Heterodimeric fusion protein that binds to IL-1 beta consisting of human extracellular domain of IL1 receptor and a mutant Fc fragment of human IGg1 and part of human IL1 receptor accessory protein)
[1] RPH-104---[2] 54, 266 💬
8 MK-2225
(Homodimeric fragment crystallizable fusion protein comprised of the extracellular domain of the human transforming growth factor beta receptor type II linked to a human IgG1 Fc domain)
[1] MK-2225---[1] 51 💬
9 Telitacicept
(FUSION PROTEIN WITH HUMAN IMMUNOGLOBULIN G1)
[1] Telitacicept---[11] 11, 13, 46, 48, 49, 51, 53, 63, 66, 222, 300 💬
10 Tralesinidase alfa
(NAGLU-IGF2 fusion protein)
[2] Rhnaglu-IGF2; Tralesinidase alfa---[1] 19 💬
11 Vasomera
(Vasoactive intestinal peptide fusion protein)
[0] ---[1] 86 💬