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KEGG DRUG

Search results

No.

DrugBank

Drug (Description in trials)

Acazicolcept
(Fc fusion protein of a human inducible T cell costimulator ligand variant immunoglobulin domain designed to inhibit simultaneously the CD28 and ICOS inflammation pathways)

[1] Acazicolcept

[1] Acazicolcept 💬

[2] CD28,
ICOS 💬

[13] Allograft rejection, Autoimmune thyroid disease, Cell adhesion molecules, Graft-versus-host disease, Intestinal immune network for IgA production, Measles, PD-L1 expression and PD-1 checkpoint pathway in cancer, Primary immunodeficiency, Rheumatoid arthritis, Systemic lupus erythematosus, T cell receptor signaling pathway, Type I diabetes mellitus, Viral myocarditis 💬

[1] 49 💬

Antilymphocyte immunoglobulin (horse)
(Antilymphocyte immunoglobulin (horse))

[3] ANTI-thymocyte globulin; Hatg; Horse ANTI-thymocyte globulin

[1] Anti-human thymocyte immunoglobulin, equine (Anti-human thymocyte immunoglobulin, equine) 💬

[3] 60, 285, 326 💬

Antithymocyte immunoglobulin (rabbit)
(Antithymocyte immunoglobulin)

[9] ANTI-thymocyte globulin; Antithymocyte immunoglobulin; Lapine T-lymphocyte immune globulin; Rabbit ANTI-human thymocyte immunoglobulin; Rabbit antithymocyte globulin; Rabbit ATG; Ratg; Thymoglobulin; Thymoglobuline

[1] Anti-human thymocyte immunoglobulin, rabbit (Anti-human thymocyte immunoglobulin, rabbit) 💬

[11] CD2,
CD3D,
CD3E,
CD3G,
CD4,
CD5,
CD7,
CD8A,
CD8B,
IL2RA,
ITGAL 💬

Name	Full Name
CD2	CD2 molecule
CD3D	CD3 delta subunit of T-cell receptor complex
CD3E	CD3 epsilon subunit of T-cell receptor complex
CD3G	CD3 gamma subunit of T-cell receptor complex
CD4	CD4 molecule
CD5	CD5 molecule
CD7	CD7 molecule
CD8A	CD8 subunit alpha
CD8B	CD8 subunit beta
IL2RA	interleukin 2 receptor subunit alpha
ITGAL	integrin subunit alpha L

[31] Antigen processing and presentation, Cell adhesion molecules, Chagas disease, Cytokine-cytokine receptor interaction, Endocytosis, Epstein-Barr virus infection, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, Human immunodeficiency virus 1 infection, JAK-STAT signaling pathway, Leukocyte transendothelial migration, Malaria, Measles, Natural killer cell mediated cytotoxicity, Neutrophil extracellular trap formation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pathways in cancer, Primary immunodeficiency, Rap1 signaling pathway, Regulation of actin cytoskeleton, Rheumatoid arthritis, Staphylococcus aureus infection, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Viral life cycle - HIV-1, Viral myocarditis, Viral protein interaction with cytokine and cytokine receptor, Virion - Human immunodeficiency virus, Yersinia infection 💬

[13] 13, 36, 49, 51, 60, 62, 65, 96, 283, 284, 285, 286, 326 💬

Disease ID	Name
13	Multiple sclerosis
36	Epidermolysis bullosa
49	Systemic lupus erythematosus
51	Scleroderma
60	Aplastic anemia
62	Paroxysmal nocturnal hemoglobinuria
65	Primary immunodeficiency
96	Crohn disease
283	Acquired pure red cell aplasia
284	Diamond-Blackfan anemia
285	Fanconi anemia
286	Hereditary sideroblastic anemia
326	Osteopetrosis

ARGX-119
(a fully humanized immunoglobulin gamma 1 that specifically targets and activates MuSK)

[1] ARGX-119

[2] 2, 12 💬

Human immunoglobulin G
(Human normal immunoglobulin)

[6] Human immunoglobulin G; Human normal immunoglobulin; Immune globulin; Immunoglobulin; Immunoglobulin G; Intravenous immunoglobulin

[1] Globulin, immune (Human normal immunoglobulin) 💬

[9] 11, 13, 14, 43, 45, 50, 51, 63, 65 💬

Disease ID	Name
11	Myasthenia gravis
13	Multiple sclerosis
14	Chronic inflammatory demyelinating polyneuropathy
43	Microscopic polyangiitis
45	Eosinophilic granulomatosis with Polyangiitis
50	Dermatomyositis
51	Scleroderma
63	Idiopathic thrombocytopenic purpura
65	Primary immunodeficiency

OMS906
(Humanized immunoglobulin G4 monoclonal antibody directed against mannan-binding lectin-associated serine protease-3)

[0]

[1] 62 💬

Talquetamab
(IMMUNOGLOBULIN G4)

[1] Talquetamab

[1] Talquetamab 💬

[1] CD3E 💬

[11] Chagas disease, Epstein-Barr virus infection, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, Human immunodeficiency virus 1 infection, Measles, PD-L1 expression and PD-1 checkpoint pathway in cancer, Primary immunodeficiency, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation 💬

[1] 28 💬

Telitacicept
(FUSION PROTEIN WITH HUMAN IMMUNOGLOBULIN G1)

[1] Telitacicept

[11] 11, 13, 46, 48, 49, 51, 53, 63, 66, 222, 300 💬

Disease ID	Name
11	Myasthenia gravis
13	Multiple sclerosis
46	Malignant rheumatoid arthritis
48	Primary antiphospholipid syndrome
49	Systemic lupus erythematosus
51	Scleroderma
53	Sjogren syndrome
63	Idiopathic thrombocytopenic purpura
66	IgA nephropathy
222	Primary nephrotic syndrome
300	IgG4-related disease