Target Gene/Pathway Pathway / Gene

  

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No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank Disease ID
1 SV2C [1] ECM-receptor interaction D11842 Padsevonil [1] 149
2 ITGA4 [11] PI3K-Akt signaling pathway, Focal adhesion, ECM-receptor interaction, Hematopoietic cell lineage, Leukocyte transendothelial migration, Intestinal immune network for IgA production, Regulation of actin cytoskeleton, Yersinia infection, Leishmaniasis, Human papillomavirus infection, Hypertrophic cardiomyopathy D06590 Firategrast [1] 13
3 ITGA4 [11] PI3K-Akt signaling pathway, Focal adhesion, ECM-receptor interaction, Hematopoietic cell lineage, Leukocyte transendothelial migration, Intestinal immune network for IgA production, Regulation of actin cytoskeleton, Yersinia infection, Leishmaniasis, Human papillomavirus infection, Hypertrophic cardiomyopathy D06886 Natalizumab [6] 13, 15, 25, 46, 63, 96
4 ITGA4 [11] PI3K-Akt signaling pathway, Focal adhesion, ECM-receptor interaction, Hematopoietic cell lineage, Leukocyte transendothelial migration, Intestinal immune network for IgA production, Regulation of actin cytoskeleton, Yersinia infection, Leishmaniasis, Human papillomavirus infection, Hypertrophic cardiomyopathy D08083 Vedolizumab [3] 94, 96, 97
5 ITGA4 [11] PI3K-Akt signaling pathway, Focal adhesion, ECM-receptor interaction, Hematopoietic cell lineage, Leukocyte transendothelial migration, Intestinal immune network for IgA production, Regulation of actin cytoskeleton, Yersinia infection, Leishmaniasis, Human papillomavirus infection, Hypertrophic cardiomyopathy D10540 Abrilumab [2] 96, 97
6 ITGB7 [8] PI3K-Akt signaling pathway, Focal adhesion, ECM-receptor interaction, Intestinal immune network for IgA production, Regulation of actin cytoskeleton, Human papillomavirus infection, Transcriptional misregulation in cancer, Hypertrophic cardiomyopathy D08083 Vedolizumab [3] 94, 96, 97
7 ITGB7 [8] PI3K-Akt signaling pathway, Focal adhesion, ECM-receptor interaction, Intestinal immune network for IgA production, Regulation of actin cytoskeleton, Human papillomavirus infection, Transcriptional misregulation in cancer, Hypertrophic cardiomyopathy D09901 Etrolizumab [2] 96, 97
8 ITGB7 [8] PI3K-Akt signaling pathway, Focal adhesion, ECM-receptor interaction, Intestinal immune network for IgA production, Regulation of actin cytoskeleton, Human papillomavirus infection, Transcriptional misregulation in cancer, Hypertrophic cardiomyopathy D10540 Abrilumab [2] 96, 97
9 VWF [6] PI3K-Akt signaling pathway, Focal adhesion, ECM-receptor interaction, Platelet activation, Neutrophil extracellular trap formation, Human papillomavirus infection D11160 Caplacizumab [1] 64
10 SV2B [1] ECM-receptor interaction D11842 Padsevonil [1] 149
11 SV2A [1] ECM-receptor interaction D00709 Levetiracetam [5] 2, 4, 6, 13, 307
12 SV2A [1] ECM-receptor interaction D08879 Brivaracetam [2] 149, 309
13 SV2A [1] ECM-receptor interaction D11842 Padsevonil [1] 149