Target Gene/Pathway Pathway / Gene

  

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No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank 指定難病告示番号
1 ABCC8 💬 3件: ABC transporters, Insulin secretion, Type II diabetes mellitus Minoxidil 💬 Minoxidil 1件: 179 💬
2 AGTR1 💬 17件: Calcium signaling pathway, cGMP-PKG signaling pathway, Phospholipase D signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Apelin signaling pathway, Renin-angiotensin system, Renin secretion, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, AGE-RAGE signaling pathway in diabetic complications, Cushing syndrome, Coronavirus disease - COVID-19, Pathways in cancer, Diabetic cardiomyopathy Losartan 💬 Losartan 18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
3 AGTR1 💬 17件: Calcium signaling pathway, cGMP-PKG signaling pathway, Phospholipase D signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Apelin signaling pathway, Renin-angiotensin system, Renin secretion, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, AGE-RAGE signaling pathway in diabetic complications, Cushing syndrome, Coronavirus disease - COVID-19, Pathways in cancer, Diabetic cardiomyopathy Losartan potassium 💬 Losartan 18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
4 DRD2 💬 10件: Rap1 signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Alcoholism Buspirone 💬 Buspirone 3件: 6, 51, 179 💬
5 DRD2 💬 10件: Rap1 signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Alcoholism Buspirone hydrochloride 💬 Buspirone 3件: 6, 51, 179 💬
6 HRH1 💬 4件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Inflammatory mediator regulation of TRP channels Clemastine 💬 Clemastine 2件: 13, 179 💬
7 HRH1 💬 4件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Inflammatory mediator regulation of TRP channels Clemastine fumarate 💬 Clemastine 2件: 13, 179 💬
8 HTR1 💬 5件: cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Serotonergic synapse, Taste transduction Buspirone hydrochloride 💬 Buspirone 3件: 6, 51, 179 💬
9 HTR1 💬 5件: cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Serotonergic synapse, Taste transduction Buspirone 💬 Buspirone 3件: 6, 51, 179 💬
10 KCNJ11 💬 3件: Insulin secretion, GnRH secretion, Type II diabetes mellitus Minoxidil 💬 Minoxidil 1件: 179 💬
11 SLC6A2 💬 2件: Neuroactive ligand signaling, Synaptic vesicle cycle Methylphenidate 💬 Methylphenidate 7件: 6, 13, 34, 84, 113, 179, 206 💬
12 SLC6A2 💬 2件: Neuroactive ligand signaling, Synaptic vesicle cycle Methylphenidate hydrochloride 💬 Methylphenidate 7件: 6, 13, 34, 84, 113, 179, 206 💬
13 SLC6A3 💬 8件: Neuroactive ligand signaling, Synaptic vesicle cycle, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Alcoholism Methylphenidate 💬 Methylphenidate 7件: 6, 13, 34, 84, 113, 179, 206 💬
14 SLC6A3 💬 8件: Neuroactive ligand signaling, Synaptic vesicle cycle, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Alcoholism Methylphenidate hydrochloride 💬 Methylphenidate 7件: 6, 13, 34, 84, 113, 179, 206 💬