Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank Drug (Description in trials) KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1 Abatacept [1] ABATACEPT[1] Abatacept 💬 [2] CD80,
CD86 💬 		[14] Allograft rejection, Autoimmune thyroid disease, Cell adhesion molecule (CAM) interaction, Graft-versus-host disease, IgSF CAM signaling, Intestinal immune network for IgA production, Kaposi sarcoma-associated herpesvirus infection, Rheumatoid arthritis, Systemic lupus erythematosus, Toll-like receptor signaling pathway, Transcriptional misregulation in cancer, Type I diabetes mellitus, Viral myocarditis, Virion - Adenovirus 💬[28] 2, 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 223, 271, 284, 285, 300 💬
2 Acetaminophen [2] Acetaminophen; Paracetamol[1] Acetaminophen 💬 [2] PTGS1,
PTGS2 💬 		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Efferocytosis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[19] 11, 13, 19, 34, 35, 46, 49, 51, 63, 70, 77, 86, 96, 222, 231, 256, 271, 300, 337 💬
3 Acetate [1] Acetate---[52] 1, 2, 6, 10, 11, 13, 22, 35, 40, 46, 49, 51, 60, 63, 64, 65, 66, 67, 70, 71, 73, 75, 76, 77, 78, 79, 81, 83, 85, 86, 88, 89, 90, 96, 97, 113, 145, 156, 158, 162, 171, 206, 222, 223, 224, 225, 227, 235, 251, 265, 298, 299 💬
4 Acetazolamide [1] Acetazolamide[2] Acetazolamide ,
Acetazolamide sodium 💬 		[13] CA1,
CA12,
CA13,
CA14,
CA2,
CA3,
CA4,
CA5A,
CA5B,
CA6,
CA7,
CA8,
CA9 💬 		[6] Bile secretion, Collecting duct acid secretion, Gastric acid secretion, Nitrogen metabolism, Pancreatic secretion, Proximal tubule bicarbonate reclamation 💬[8] 13, 67, 90, 115, 155, 222, 225, 230 💬
5 Adalimumab [1] Adalimumab[1] Adalimumab 💬 [1] TNF 💬 [66] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[22] 19, 37, 38, 40, 41, 46, 55, 56, 84, 90, 96, 97, 107, 151, 160, 162, 164, 222, 226, 269, 270, 271 💬
6 Aldosterone [1] Aldosterone[1] Aldosterone 💬 [1] NR3C2 💬 [1] Aldosterone-regulated sodium reabsorption 💬[3] 57, 75, 222 💬
7 Alfacalcidol [1] Alfacalcidol[1] Alfacalcidol 💬 [1] VDR 💬 [5] Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬[10] 41, 46, 49, 50, 96, 107, 222, 223, 235, 238 💬
8 Aliskiren [1] Aliskiren[2] Aliskiren ,
Aliskiren fumarate 💬 		[1] REN 💬 [3] Diabetic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬[4] 66, 167, 222, 223 💬
9 Ambrisentan [1] Ambrisentan[1] Ambrisentan 💬 [1] EDNRA 💬 [7] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Pathways in cancer, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[10] 51, 66, 84, 85, 86, 88, 210, 211, 218, 222 💬
10 Amiloride [2] Amiloride; Amiloride Hydrochloride[2] Amiloride hydrochloride ,
Amiloride 💬 		[3] SCNN1A,
SCNN1B,
SCNN1G 💬 		[2] Aldosterone-regulated sodium reabsorption, Taste transduction 💬[5] 13, 67, 222, 225, 299 💬
11 Amlodipine [1] Amlodipine[4] Amlodipine besylate ,
Amlodipine maleate ,
Amlodipine ,
Amlodipine benzoate 💬 		[4] CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S 💬 		[37] Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[6] 51, 67, 79, 113, 222, 298 💬
12 Amoxicillin [2] Amoxicilina; Amoxicillin[3] Amoxicillin ,
Amoxicillin sodium ,
Amoxicillin 💬 		--[9] 6, 46, 63, 94, 96, 97, 222, 223, 299 💬
13 Angiotensin II [1] Angiotensin II[3] Angiotensin II ,
Angiotensin II ,
Angiotensin II acetate 💬 		[2] AGTR1,
AGTR2 💬 		[17] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Hormone signaling, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[2] 66, 222 💬
14 Anti-CD19 CAR-T cells [2] Anti-CD19 CAR-T cells; CD19 CAR-T cells---[6] 46, 49, 50, 51, 53, 222 💬
15 Apixaban [1] Apixaban[1] Apixaban 💬 [1] F10 💬 [1] Complement and coagulation cascades 💬[6] 48, 96, 97, 222, 223, 279 💬
16 Atacicept [2] Atacicept; TACI-Fc5[1] Atacicept 💬 [2] TNFSF13,
TNFSF13B 💬 		[4] Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis 💬[5] 13, 46, 49, 66, 222 💬
17 Atorvastatin [3] Atorvastatin; ATORVASTATIN CALCIUM; Atorvastatina[2] Atorvastatin calcium ,
Atorvastatin 💬 		[1] HMGCR 💬 [3] AMPK signaling pathway, Bile secretion, Terpenoid backbone biosynthesis 💬[21] 13, 22, 46, 49, 51, 58, 63, 67, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 297, 299 💬
18 Atrasentan [1] ATRASENTAN[1] Atrasentan hydrochloride 💬 [1] EDNRA 💬 [7] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Pathways in cancer, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[3] 66, 218, 222 💬
19 Azithromycin [4] Azithromycin; AZITHROMYCIN DIHYDRATE; Azithromycin monohydrate; AZITHROMYCINE[3] Azithromycin hydrate ,
Azithromycin ,
Azithromycin 💬 		--[8] 13, 84, 85, 96, 222, 228, 299, 340 💬
20 Bardoxolone [1] Bardoxolone[1] Bardoxolone 💬 --[7] 66, 67, 84, 85, 86, 218, 222 💬
21 Bardoxolone methyl [1] Bardoxolone methyl[1] Bardoxolone methyl 💬 --[7] 66, 67, 84, 85, 86, 218, 222 💬
22 Basiliximab [1] Basiliximab[1] Basiliximab 💬 [1] IL2RA 💬 [11] Cytokine-cytokine receptor interaction, Endocytosis, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, JAK-STAT signaling pathway, Measles, PI3K-Akt signaling pathway, Pathways in cancer, Th1 and Th2 cell differentiation, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[5] 2, 50, 97, 222, 228 💬
23 Belimumab [1] Belimumab[1] Belimumab 💬 [1] TNFSF13B 💬 [4] Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis 💬[17] 11, 13, 43, 44, 46, 48, 49, 50, 51, 53, 63, 66, 95, 222, 223, 296, 300 💬
24 Benazepril [1] Benazepril[2] Benazepril hydrochloride ,
Benazepril 💬 		[1] ACE 💬 [6] Chagas disease, Coronavirus disease, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬[5] 49, 57, 218, 222, 224 💬
25 Bleselumab [1] Bleselumab[1] Bleselumab 💬 [1] CD40 💬 [17] Allograft rejection, Asthma, Autoimmune thyroid disease, Cell adhesion molecule (CAM) interaction, Cytokine-cytokine receptor interaction, Epstein-Barr virus infection, Human T-cell leukemia virus 1 infection, Intestinal immune network for IgA production, Lipid and atherosclerosis, Malaria, NF-kappa B signaling pathway, Primary immunodeficiency, Systemic lupus erythematosus, Toll-like receptor signaling pathway, Toxoplasmosis, Transcriptional misregulation in cancer, Viral myocarditis 💬[1] 222 💬
26 Blinatumomab [1] Blinatumomab[1] Blinatumomab 💬 [4] CD19,
CD3D,
CD3E,
CD3G 💬 		[13] B cell receptor signaling pathway, Chagas disease, Epstein-Barr virus infection, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, Human immunodeficiency virus 1 infection, Measles, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Primary immunodeficiency, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation 💬[4] 11, 46, 49, 222 💬
27 Bortezomib [1] Bortezomib[1] Bortezomib 💬 [1] PSMB5 💬 [8] Alzheimer disease, Amyotrophic lateral sclerosis, Huntington disease, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Prion disease, Proteasome, Spinocerebellar ataxia 💬[19] 11, 13, 26, 28, 46, 49, 51, 61, 63, 64, 66, 172, 222, 223, 228, 256, 283, 288, 331 💬
28 Budoprutug [1] Budoprutug---[3] 49, 63, 222 💬
29 Butyric Acid [3] Butyrate; Butyric Acid; Sodium butyrate[1] Sodium butyrate 💬 --[3] 46, 156, 222 💬
30 Calcium [1] Calcium---[39] 2, 3, 6, 13, 15, 19, 46, 48, 49, 51, 53, 56, 62, 67, 68, 71, 74, 75, 79, 84, 90, 93, 94, 95, 96, 97, 156, 186, 214, 215, 222, 224, 235, 256, 265, 271, 274, 298, 299 💬
31 Candesartan [1] Candesartan[1] Candesartan 💬 [1] AGTR1 💬 [17] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Hormone signaling, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[4] 57, 58, 67, 222 💬
32 Chlorambucil [1] Chlorambucil[1] Chlorambucil 💬 --[2] 222, 223 💬
33 Cholecalciferol [4] Cholecalciferol; COLECALCIFEROL; Vitamin D-3; Vitamin D3[1] Cholecalciferol 💬 [1] VDR 💬 [5] Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬[10] 13, 19, 34, 46, 49, 96, 97, 222, 298, 299 💬
34 Cholesterol [1] Cholesterol[1] Cholesterol 💬 --[10] 8, 19, 71, 79, 90, 160, 222, 259, 261, 310 💬
35 Clarithromycin [1] CLARITHROMYCIN[1] Clarithromycin 💬 --[10] 6, 46, 63, 84, 96, 97, 222, 223, 228, 299 💬
36 Clopidogrel [1] Clopidogrel[4] Clopidogrel bisulfate ,
Clopidogrel ,
Clopidogrel hydrochloride ,
Clopidogrel besilate 💬 		[1] P2RY12 💬 [3] Efferocytosis, Neuroactive ligand signaling, Platelet activation 💬[7] 40, 49, 51, 62, 71, 86, 222 💬
37 Corticotropin [3] ACTH; Adrenocorticotropic Hormone; Corticotropin[2] Corticotropin ,
Corticotropin, repository 💬 		[1] MC2R 💬 [6] Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome, Hormone signaling, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[10] 2, 13, 46, 75, 78, 81, 84, 145, 205, 222 💬
38 Creatinine [1] Creatinine[1] Creatinine 💬 --[9] 2, 46, 49, 60, 66, 70, 96, 97, 222 💬
39 CXA-10 [1] CXA-10---[2] 86, 222 💬
40 Cyclophosphamide [5] Ciclofosfamida; CICLOFOSFAMIDE; Cyclophosphamid; Cyclophosphamide; CYCLOPHOSPHAMIDE MONOHYDRATE[2] Cyclophosphamide ,
Cyclophosphamide 💬 		--[50] 11, 13, 14, 16, 19, 20, 26, 28, 34, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 56, 60, 61, 62, 63, 65, 66, 84, 93, 96, 162, 164, 172, 205, 221, 222, 223, 224, 256, 265, 274, 283, 284, 285, 288, 326, 331 💬
41 Cyclosporine [7] CICLOSPORIN; Ciclosporina; Ciclosporine; CYCLOSPORIN; Cyclosporin A; Cyclosporine; Cyclosporine A[1] Cyclosporine 💬 [5] PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬 		[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬[39] 11, 14, 19, 20, 28, 36, 40, 41, 42, 45, 46, 49, 50, 53, 56, 58, 60, 61, 62, 63, 64, 65, 67, 90, 95, 97, 107, 118, 162, 164, 222, 223, 226, 228, 234, 283, 284, 285, 302 💬
42 Dalteparin [2] Dalteparin; Dalteparin Sodium[1] Dalteparin sodium 💬 [1] SERPINC1 💬 [1] Complement and coagulation cascades 💬[3] 222, 223, 327 💬
43 Dapagliflozin [1] Dapagliflozin[1] Dapagliflozin 💬 --[16] 6, 19, 28, 40, 41, 49, 57, 66, 67, 86, 88, 97, 210, 215, 218, 222 💬
44 Daratumumab [1] DARATUMUMAB[1] Daratumumab 💬 [1] CD38 💬 [6] Calcium signaling pathway, Hematopoietic cell lineage, Nicotinate and nicotinamide metabolism, Oxytocin signaling pathway, Pancreatic secretion, Salivary secretion 💬[13] 13, 16, 28, 39, 46, 48, 49, 60, 63, 222, 223, 288, 331 💬
45 Dexamethasone [4] Dexametasone; Dexamethason; Dexamethasone; Dexamethasone sodium phosphate[3] Dexamethasone ,
Dexamethasone sodium phosphate ,
Dexamethasone phosphate 💬 		[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[29] 13, 14, 16, 19, 28, 35, 46, 53, 63, 64, 65, 70, 71, 74, 75, 81, 84, 90, 96, 97, 162, 222, 223, 235, 257, 283, 296, 299, 331 💬
46 Diphenhydramine [2] Diphenhydramine; Diphenhydramine hydrochloride[4] Diphenhydramine ,
Diphenhydramine hydrochloride ,
Diphenhydramine salicylate ,
Diphenhydramine citrate 💬 		[1] HRH1 💬 [4] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction 💬[12] 11, 13, 19, 49, 51, 63, 70, 86, 96, 222, 256, 300 💬
47 Dipyridamole [1] Dipyridamole[1] Dipyridamole 💬 [2] PDE4A,
PDE5A 💬 		[5] Morphine addiction, Parathyroid hormone synthesis, secretion and action, Purine metabolism, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[7] 46, 49, 51, 66, 96, 222, 224 💬
48 Dupilumab [1] Dupilumab[1] Dupilumab 💬 [1] IL4R 💬 [8] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, Inflammatory bowel disease, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer, Th1 and Th2 cell differentiation, Th17 cell differentiation 💬[8] 51, 97, 98, 160, 162, 222, 300, 306 💬
49 Edoxaban [1] Edoxaban[3] Edoxaban tosilate hydrate ,
Edoxaban ,
Edoxaban tosylate 💬 		[1] F10 💬 [1] Complement and coagulation cascades 💬[4] 46, 71, 88, 222 💬
50 Empagliflozin [1] Empagliflozin[1] Empagliflozin 💬 --[17] 28, 46, 57, 58, 65, 67, 72, 77, 86, 96, 97, 113, 222, 223, 257, 298, 299 💬
51 Enalapril [2] Enalapril; ENALAPRIL MALEATE[2] Enalapril maleate ,
Enalapril 💬 		[1] ACE 💬 [6] Chagas disease, Coronavirus disease, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬[10] 13, 19, 46, 57, 66, 113, 210, 222, 223, 279 💬
52 Enoxaparin [2] Enoxaparin; Enoxaparin Sodium[2] Enoxaparin sodium ,
Adomiparin 💬 		[1] SERPINC1 💬 [1] Complement and coagulation cascades 💬[6] 46, 48, 71, 222, 223, 327 💬
53 Entecavir [1] Entecavir[2] Entecavir ,
Entecavir 💬 		--[8] 46, 56, 96, 97, 107, 222, 223, 271 💬
54 Evolocumab [1] EVOLOCUMAB[1] Evolocumab 💬 [1] PCSK9 💬 [1] Cholesterol metabolism 💬[2] 79, 222 💬
55 Fecal microbiota [3] Fecal Microbial Transplantation; Fecal Microbiota; Fecal Microbiota Transplantation---[14] 2, 6, 13, 49, 63, 66, 93, 94, 96, 97, 99, 222, 271, 298 💬
56 Felzartamab [1] Felzartamab---[2] 66, 222 💬
57 Filgotinib [2] FILGOTINIB; Filgotinib Maleate[2] Filgotinib ,
Filgotinib maleate 💬 		[4] JAK1,
JAK2,
JAK3,
TYK2 💬 		[39] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease, Efferocytosis, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Hormone signaling, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Necroptosis, Non-small cell lung cancer, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Primary immunodeficiency, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬[10] 46, 53, 56, 96, 97, 107, 222, 271, 300, 331 💬
58 Finerenone [1] Finerenone[1] Finerenone 💬 [1] NR3C2 💬 [1] Aldosterone-regulated sodium reabsorption 💬[5] 66, 218, 222, 223, 224 💬
59 Fludarabine [3] FLUDARABINA; Fludarabine; Fludarabine phosphate[2] Fludarabine phosphate ,
Fludarabine 💬 		[1] RRM1 💬 [4] Drug metabolism - other enzymes, Glutathione metabolism, Purine metabolism, Pyrimidine metabolism 💬[30] 11, 13, 14, 16, 19, 28, 34, 35, 36, 44, 46, 49, 50, 51, 60, 61, 62, 63, 65, 85, 96, 107, 164, 222, 223, 283, 284, 285, 286, 326 💬
60 Fluvastatin [1] Fluvastatin[2] Fluvastatin sodium ,
Fluvastatin 💬 		[1] HMGCR 💬 [3] AMPK signaling pathway, Bile secretion, Terpenoid backbone biosynthesis 💬[4] 48, 79, 218, 222 💬
61 Fresolimumab [2] Fresolimumab; GC1008[1] Fresolimumab 💬 [3] TGFB1,
TGFB2,
TGFB3 💬 		[37] AGE-RAGE signaling pathway in diabetic complications, Amoebiasis, Cell cycle, Cellular senescence, Chagas disease, Chronic myeloid leukemia, Colorectal cancer, Cytokine-cytokine receptor interaction, Diabetic cardiomyopathy, Dilated cardiomyopathy, Efferocytosis, FoxO signaling pathway, Gastric cancer, Hepatitis B, Hepatocellular carcinoma, Hippo signaling pathway, Human T-cell leukemia virus 1 infection, Hypertrophic cardiomyopathy, Inflammatory bowel disease, Integrin signaling, Intestinal immune network for IgA production, Leishmaniasis, MAPK signaling pathway, Malaria, MicroRNAs in cancer, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pancreatic cancer, Pathways in cancer, Proteoglycans in cancer, Relaxin signaling pathway, Renal cell carcinoma, Rheumatoid arthritis, TGF-beta signaling pathway, Th17 cell differentiation, Toxoplasmosis, Tuberculosis 💬[3] 51, 222, 274 💬
62 Frexalimab [1] Frexalimab[1] Frexalimab 💬 [1] CD40LG 💬 [14] Allograft rejection, Asthma, Autoimmune thyroid disease, Cell adhesion molecule (CAM) interaction, Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, Lipid and atherosclerosis, Malaria, NF-kappa B signaling pathway, Primary immunodeficiency, Systemic lupus erythematosus, T cell receptor signaling pathway, Toxoplasmosis, Viral myocarditis 💬[3] 13, 222, 223 💬
63 Furosemide [1] FUROSEMIDE[1] Furosemide 💬 [1] SLC12A2 💬 [3] Pancreatic secretion, Salivary secretion, Vibrio cholerae infection 💬[5] 6, 57, 77, 86, 222 💬
64 Galactose [2] D-Galactose; Galactose[1] Galactose 💬 --[4] 66, 171, 222, 257 💬
65 Gold [1] Gold---[71] 2, 5, 6, 11, 13, 17, 19, 21, 22, 28, 34, 35, 46, 49, 50, 53, 54, 56, 57, 58, 60, 63, 64, 65, 66, 68, 71, 75, 76, 77, 79, 84, 85, 86, 88, 91, 93, 95, 96, 97, 98, 107, 113, 127, 137, 158, 162, 167, 171, 193, 206, 215, 218, 222, 223, 224, 226, 227, 228, 230, 235, 271, 291, 294, 296, 298, 299, 310, 318, 331, 340 💬
66 Hydrochlorothiazide [1] Hydrochlorothiazide[1] Hydrochlorothiazide 💬 [1] SLC12A3 💬 [1] Parathyroid hormone synthesis, secretion and action 💬[5] 13, 67, 222, 225, 235 💬
67 Hydroxychloroquine [2] Hydroxychloroquine; HYDROXYCHLOROQUINE SULFATE[2] Hydroxychloroquine sulfate ,
Hydroxychloroquine 💬 		--[29] 6, 13, 34, 41, 43, 44, 45, 46, 48, 49, 53, 56, 63, 66, 84, 89, 90, 96, 97, 107, 218, 222, 223, 224, 234, 254, 271, 298, 299 💬
68 Indobufen [1] Indobufen[1] Indobufen 💬 [2] PTGS1,
PTGS2 💬 		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Efferocytosis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[1] 222 💬
69 Iptacopan [1] Iptacopan[2] Iptacopan ,
Iptacopan hydrochloride 💬 		[1] CFB 💬 [3] Complement and coagulation cascades, Coronavirus disease, Staphylococcus aureus infection 💬[8] 11, 61, 62, 63, 66, 109, 222, 223 💬
70 Irbesartan [1] Irbesartan[1] Irbesartan 💬 [1] AGTR1 💬 [17] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Hormone signaling, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[6] 57, 66, 167, 168, 222, 223 💬
71 Lanraplenib [1] Lanraplenib[1] Lanraplenib 💬 --[2] 53, 222 💬
72 Lansoprazole [1] Lansoprazole[1] Lansoprazole 💬 [2] ATP4A,
ATP4B 💬 		[3] Collecting duct acid secretion, Gastric acid secretion, Oxidative phosphorylation 💬[8] 63, 71, 85, 98, 166, 222, 223, 299 💬
73 Levamisole [2] Levamisole; Levamisole hydrochloride[2] Levamisole hydrochloride ,
Levamisole 💬 		--[4] 60, 61, 62, 222 💬
74 Lisinopril [1] Lisinopril[2] Lisinopril ,
Lisinopril 💬 		[1] ACE 💬 [6] Chagas disease, Coronavirus disease, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬[9] 19, 46, 49, 57, 66, 67, 113, 222, 223 💬
75 Losartan [2] Losartan; LOSARTAN POTASSIUM[2] Losartan potassium ,
Losartan 💬 		[1] AGTR1 💬 [17] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Hormone signaling, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[20] 17, 19, 36, 46, 57, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 223, 299 💬
76 Losmapimod [1] Losmapimod[1] Losmapimod 💬 [4] MAPK11,
MAPK12,
MAPK13,
MAPK14 💬 		[64] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Alcoholic liver disease, Amyotrophic lateral sclerosis, C-type lectin receptor signaling pathway, Cadherin signaling, Cellular senescence, Chagas disease, Chemical carcinogenesis - reactive oxygen species, Coronavirus disease, Diabetic cardiomyopathy, Dopaminergic synapse, Efferocytosis, Epithelial cell signaling in Helicobacter pylori infection, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, FoxO signaling pathway, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hepatitis B, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, IL-17 signaling pathway, IgSF CAM signaling, Inflammatory mediator regulation of TRP channels, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Leukocyte transendothelial migration, Lipid and atherosclerosis, MAPK signaling pathway, NOD-like receptor signaling pathway, Neurotrophin signaling pathway, Neutrophil extracellular trap formation, Non-alcoholic fatty liver disease, Oocyte meiosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Platelet activation, Prion disease, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rap1 signaling pathway, Relaxin signaling pathway, Retrograde endocannabinoid signaling, Salmonella infection, Shigellosis, Signaling pathways regulating pluripotency of stem cells, Sphingolipid signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Thermogenesis, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, VEGF signaling pathway, Yersinia infection 💬[2] 113, 222 💬
77 Melphalan [2] Melphalan; Melphalan Hydrochloride[2] Melphalan ,
Melphalan hydrochloride 💬 		--[19] 11, 13, 14, 19, 20, 28, 34, 46, 60, 62, 65, 96, 107, 164, 222, 234, 284, 285, 299 💬
78 Metformin [4] Metformin; Metformin hydrochloride; Metformina; Metformine[2] Metformin hydrochloride ,
Metformin 💬 		[2] PRKAA1,
PRKAA2 💬 		[20] AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬[31] 2, 6, 8, 13, 46, 49, 60, 65, 66, 67, 74, 75, 77, 81, 84, 85, 86, 97, 113, 127, 158, 206, 218, 222, 225, 233, 265, 285, 298, 299, 301 💬
79 Methylprednisolone [3] Methylprednisolon; Methylprednisolone; METHYLPREDNISOLONE ACETATE[2] Methylprednisolone ,
Methylprednisolone acetate 💬 		[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[51] 2, 6, 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 95, 96, 97, 111, 127, 145, 162, 164, 211, 222, 223, 224, 271, 283, 284, 285, 296, 300 💬
80 Methylprednisolone hemisuccinate [3] Methylprednisolone hemisuccinate; Methylprednisolone sodium succinate; Methylprednisolone succinate[2] Methylprednisolone sodium succinate ,
Methylprednisolone hemisuccinate 💬 		[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[8] 13, 46, 49, 50, 51, 85, 211, 222 💬
81 Methylprednisone [1] Methylprednisone---[4] 46, 66, 85, 222 💬
82 Metolazone [1] Metolazone[1] Metolazone 💬 [1] SLC12A3 💬 [1] Parathyroid hormone synthesis, secretion and action 💬[1] 222 💬
83 Mizoribine [1] Mizoribine[1] Mizoribine 💬 [2] IMPDH1,
IMPDH2 💬 		[2] Drug metabolism - other enzymes, Purine metabolism 💬[8] 46, 49, 51, 53, 66, 94, 222, 224 💬
84 Montelukast [2] Montelukast; MONTELUKAST SODIUM[2] Montelukast sodium ,
Montelukast 💬 		[1] CYSLTR1 💬 [2] Calcium signaling pathway, Neuroactive ligand-receptor interaction 💬[10] 6, 13, 19, 46, 61, 63, 85, 98, 222, 228 💬
85 Mycophenolate mofetil [1] Mycophenolate mofetil[2] Mycophenolate mofetil ,
Mycophenolate mofetil hydrochloride 💬 		[2] IMPDH1,
IMPDH2 💬 		[2] Drug metabolism - other enzymes, Purine metabolism 💬[38] 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 46, 49, 51, 53, 57, 60, 61, 62, 63, 65, 66, 93, 95, 96, 118, 162, 164, 222, 223, 224, 226, 234, 283, 284, 285, 300 💬
86 Mycophenolic acid [5] ACIDO MICOFENOLICO; MICOFENOLICO ACIDO; Mycophenolate; Mycophenolate sodium; Mycophenolic acid[2] Mycophenolate sodium ,
Mycophenolic acid 💬 		[2] IMPDH1,
IMPDH2 💬 		[2] Drug metabolism - other enzymes, Purine metabolism 💬[11] 11, 43, 49, 51, 53, 60, 66, 96, 222, 223, 228 💬
87 Narsoplimab [1] Narsoplimab[1] Narsoplimab 💬 [1] MASP2 💬 [3] Complement and coagulation cascades, Coronavirus disease, Staphylococcus aureus infection 💬[3] 66, 222, 223 💬
88 Obinutuzumab [1] OBINUTUZUMAB[1] Obinutuzumab 💬 [1] MS4A1 💬 [1] Hematopoietic cell lineage 💬[6] 43, 44, 49, 63, 222, 223 💬
89 Ofatumumab [2] HuMax-CD20; OFATUMUMAB[1] Ofatumumab 💬 [1] MS4A1 💬 [1] Hematopoietic cell lineage 💬[6] 11, 13, 35, 46, 222, 223 💬
90 Peginterferon alfa-2a [1] Peginterferon alfa-2a[1] Peginterferon alfa-2a 💬 [2] IFNAR1,
IFNAR2 💬 		[18] Coronavirus disease, Cytokine-cytokine receptor interaction, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Measles, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Osteoclast differentiation, PI3K-Akt signaling pathway, Pathways in cancer, Toll-like receptor signaling pathway 💬[1] 222 💬
91 Pentoxifylline [1] Pentoxifylline[1] Pentoxifylline 💬 --[13] 6, 26, 46, 56, 84, 93, 96, 97, 113, 222, 223, 296, 298 💬
92 Perindopril [2] Perindopril; PERINDOPRIL ARGININE[3] Perindopril erbumine ,
Perindopril ,
Perindopril arginine 💬 		[1] ACE 💬 [6] Chagas disease, Coronavirus disease, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬[5] 57, 58, 113, 167, 222 💬
93 Pirfenidone [1] Pirfenidone[1] Pirfenidone 💬 [6] CCL2,
IL10,
IL1A,
IL1B,
IL6,
TNF 💬 		[83] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antigen processing and presentation, Apoptosis, Asthma, Autoimmune thyroid disease, C-type lectin receptor signaling pathway, Cellular senescence, Chagas disease, Chemokine signaling pathway, Coronavirus disease, Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, Dilated cardiomyopathy, Efferocytosis, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Graft-versus-host disease, HIF-1 signaling pathway, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Inflammatory mediator regulation of TRP channels, Influenza A, Insulin resistance, Intestinal immune network for IgA production, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, Measles, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Staphylococcus aureus infection, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Transcriptional misregulation in cancer, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[12] 13, 34, 40, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
94 Povetacicept [1] Povetacicept[1] Povetacicept 💬 [1] TNFRSF13B 💬 [3] Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, Primary immunodeficiency 💬[5] 11, 61, 63, 66, 222 💬
95 Praliciguat [1] Praliciguat[1] Praliciguat 💬 [3] GUCY1A1,
GUCY1A2,
GUCY1B1 💬 		[10] Circadian entrainment, Gap junction, Long-term depression, Oxytocin signaling pathway, Platelet activation, Purine metabolism, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 222 💬
96 Pravastatin [2] Pravastatin; Pravastatin sodium[2] Pravastatin sodium ,
Pravastatin 💬 		[1] HMGCR 💬 [3] AMPK signaling pathway, Bile secretion, Terpenoid backbone biosynthesis 💬[11] 13, 46, 49, 67, 79, 96, 164, 210, 222, 265, 333 💬
97 Prednisolone [3] Prednisolona; Prednisolone; Prednisolonum[1] Prednisolone 💬 [1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[48] 3, 11, 13, 14, 18, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 54, 56, 57, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 111, 113, 145, 162, 222, 223, 251, 269, 271, 296, 299, 300 💬
98 Prednisolone acetate [1] PREDNISOLONE ACETATE[1] Prednisolone acetate 💬 [1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[2] 222, 223 💬
99 Prednisone [2] Prednisona; PREDNISONE[1] Prednisone 💬 [1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[58] 2, 11, 13, 14, 18, 19, 26, 28, 35, 40, 41, 42, 43, 44, 45, 46, 48, 49, 50, 51, 53, 60, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 90, 93, 95, 96, 97, 113, 127, 145, 162, 164, 205, 222, 223, 224, 228, 251, 269, 283, 284, 285, 288, 299, 300, 303, 307, 331 💬
100 Prednisone acetate [1] Prednisone acetate[1] Prednisone acetate 💬 [1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[9] 35, 40, 46, 49, 63, 66, 162, 222, 224 💬
101 R3R01 [1] R3R01---[2] 218, 222 💬
102 Ramipril [1] Ramipril[1] Ramipril 💬 [1] ACE 💬 [6] Chagas disease, Coronavirus disease, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬[10] 46, 49, 57, 66, 67, 113, 218, 222, 223, 257 💬
103 Rilzabrutinib [1] Rilzabrutinib[1] Rilzabrutinib 💬 [1] BTK 💬 [7] B cell receptor signaling pathway, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, NF-kappa B signaling pathway, Osteoclast differentiation, Platelet activation, Primary immunodeficiency 💬[6] 35, 61, 63, 222, 223, 300 💬
104 Ripertamab [1] Ripertamab---[4] 11, 14, 63, 222 💬
105 Rituximab [1] Rituximab[1] Rituximab 💬 [1] MS4A1 💬 [1] Hematopoietic cell lineage 💬[54] 11, 13, 14, 19, 26, 34, 35, 36, 40, 41, 42, 43, 44, 45, 46, 48, 49, 50, 51, 52, 53, 55, 56, 60, 61, 62, 63, 64, 65, 66, 83, 84, 85, 86, 88, 93, 94, 96, 97, 162, 172, 222, 223, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331 💬
106 Rivaroxaban [1] Rivaroxaban[1] Rivaroxaban 💬 [1] F10 💬 [1] Complement and coagulation cascades 💬[10] 46, 48, 49, 56, 58, 75, 91, 210, 222, 271 💬
107 Rosiglitazone [2] Rosiglitazone; Rosiglitazone maleate[2] Rosiglitazone maleate ,
Rosiglitazone 💬 		[1] PPARG 💬 [12] AMPK signaling pathway, Efferocytosis, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬[7] 46, 57, 75, 77, 97, 222, 265 💬
108 Sacubitril [1] Sacubitril[1] Sacubitril 💬 [1] MME 💬 [4] Alzheimer disease, Hematopoietic cell lineage, Protein digestion and absorption, Renin-angiotensin system 💬[4] 28, 58, 210, 222 💬
109 Saquinavir [1] Saquinavir[2] Saquinavir ,
Saquinavir mesylate 💬 		--[4] 86, 222, 223, 265 💬
110 Serine [2] L-Serine; Serine[1] Serine 💬 --[5] 2, 6, 86, 96, 222 💬
111 Sinomenine [1] Sinomenine---[2] 46, 222 💬
112 Sirolimus [2] Rapamycin; Sirolimus[1] Sirolimus 💬 [1] MTOR 💬 [52] AMPK signaling pathway, Acute myeloid leukemia, Adipocytokine signaling pathway, Alzheimer disease, Amyotrophic lateral sclerosis, Apelin signaling pathway, Autophagy - animal, Autophagy - other, Breast cancer, Cellular senescence, Central carbon metabolism in cancer, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Diabetic cardiomyopathy, ErbB signaling pathway, Gastric cancer, Glioma, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatocellular carcinoma, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Huntington disease, Insulin resistance, Insulin signaling pathway, Integrated stress response (ISR) signaling pathway, Integrin signaling, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Longevity regulating pathway, Longevity regulating pathway - multiple species, Lysosome biogenesis, MicroRNAs in cancer, Neutrophil extracellular trap formation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Shigellosis, Spinocerebellar ataxia, Th17 cell differentiation, Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus, mTOR signaling pathway 💬[46] 6, 13, 15, 17, 19, 21, 34, 35, 36, 46, 48, 49, 51, 54, 57, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 97, 98, 111, 127, 137, 157, 158, 192, 222, 223, 227, 277, 278, 279, 280, 281, 283, 285, 300, 331 💬
113 Sparsentan [1] SPARSENTAN[1] Sparsentan 💬 [2] AGTR1,
EDNRA 💬 		[18] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Hormone signaling, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[4] 66, 218, 222, 223 💬
114 Spironolactone [1] Spironolactone[1] Spironolactone 💬 [1] NR3C2 💬 [1] Aldosterone-regulated sodium reabsorption 💬[12] 46, 57, 58, 67, 86, 113, 210, 214, 218, 222, 223, 225 💬
115 Succinic acid [1] Sodium succinate---[11] 13, 46, 49, 50, 51, 81, 83, 95, 97, 211, 222 💬
116 Tacrolimus [1] Tacrolimus[2] Tacrolimus ,
Tacrolimus 💬 		[5] PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬 		[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬[37] 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 57, 60, 61, 62, 63, 65, 66, 95, 96, 97, 113, 151, 158, 164, 222, 223, 224, 226, 227, 228, 234, 283, 284, 285, 286, 299 💬
117 Telitacicept [1] Telitacicept---[14] 11, 13, 14, 46, 48, 49, 51, 53, 63, 66, 162, 222, 223, 300 💬
118 Telmisartan [1] Telmisartan[1] Telmisartan 💬 [1] AGTR1 💬 [17] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Hormone signaling, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[5] 6, 57, 66, 67, 222 💬
119 Tetracosactide [3] Cosyntropin; Tetracosactide; Tetracosactide Acetate[2] Cosyntropin ,
Tetracosactide acetate 💬 		[1] MC2R 💬 [6] Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome, Hormone signaling, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[4] 83, 113, 145, 222 💬
120 Tolvaptan [1] TOLVAPTAN[1] Tolvaptan 💬 [1] AVPR2 💬 [4] Hormone signaling, Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vasopressin-regulated water reabsorption 💬[5] 67, 72, 86, 222, 225 💬
121 Torasemide [1] Torasemide[1] Torsemide 💬 [1] SLC12A2 💬 [3] Pancreatic secretion, Salivary secretion, Vibrio cholerae infection 💬[1] 222 💬
122 TRU-015 [1] TRU-015---[3] 46, 49, 222 💬
123 Valproic acid [3] Divalproex sodium; VALPROATE SODIUM; Valproic acid[3] Divalproex sodium ,
Valproic acid ,
Valproate sodium 💬 		[7] ABAT,
ALDH5A1,
CACNA1G,
CACNA1H,
CACNA1I,
GAD1,
GAD2 💬 		[16] Alanine, aspartate and glutamate metabolism, Aldosterone synthesis and secretion, Butanoate metabolism, Calcium signaling pathway, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, GABAergic synapse, GnRH secretion, MAPK signaling pathway, Propanoate metabolism, Taurine and hypotaurine metabolism, Type I diabetes mellitus, Type II diabetes mellitus, Valine, leucine and isoleucine degradation, beta-Alanine metabolism 💬[11] 3, 5, 26, 34, 51, 65, 89, 90, 145, 222, 331 💬
124 Valsartan [1] Valsartan[1] Valsartan 💬 [1] AGTR1 💬 [17] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Hormone signaling, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[11] 28, 57, 58, 66, 75, 86, 210, 218, 222, 223, 224 💬
125 Vitamin D [1] Vitamin D---[26] 3, 6, 13, 15, 19, 41, 43, 44, 46, 49, 50, 68, 74, 93, 95, 96, 97, 98, 179, 222, 228, 235, 256, 274, 298, 299 💬
126 Voclosporin [1] Voclosporin[1] Voclosporin 💬 [5] PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬 		[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬[2] 49, 222 💬
127 Warfarin [3] Warfarin; Warfarin Potassium; Warfarin Sodium[3] Warfarin sodium ,
Warfarin potassium ,
Warfarin 💬 		[2] NQO1,
VKORC1 💬 		[5] Chemical carcinogenesis - reactive oxygen species, Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Pathways in cancer, Ubiquinone and other terpenoid-quinone biosynthesis 💬[15] 6, 8, 13, 19, 46, 48, 49, 66, 85, 86, 88, 91, 96, 97, 222 💬
128 Zanubrutinib [1] Zanubrutinib[1] Zanubrutinib 💬 [1] BTK 💬 [7] B cell receptor signaling pathway, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, NF-kappa B signaling pathway, Osteoclast differentiation, Platelet activation, Primary immunodeficiency 💬[7] 13, 48, 61, 63, 222, 300, 331 💬
129 Zinc [1] Zinc---[7] 2, 56, 85, 171, 222, 223, 299 💬
130 ZUBERITAMAB [1] ZUBERITAMAB---[2] 63, 222 💬