Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank Drug (Description in trials) KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1 Abacavir [2] Abacavir; Abacavir sulfate[2] Abacavir sulfate ,
Abacavir 💬 		--[5] 2, 49, 135, 265, 325 💬
2 Abatacept [1] ABATACEPT[1] Abatacept 💬 [2] CD80,
CD86 💬 		[14] Allograft rejection, Autoimmune thyroid disease, Cell adhesion molecule (CAM) interaction, Graft-versus-host disease, IgSF CAM signaling, Intestinal immune network for IgA production, Kaposi sarcoma-associated herpesvirus infection, Rheumatoid arthritis, Systemic lupus erythematosus, Toll-like receptor signaling pathway, Transcriptional misregulation in cancer, Type I diabetes mellitus, Viral myocarditis, Virion - Adenovirus 💬[28] 2, 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 223, 271, 284, 285, 300 💬
3 Acamprosate [2] Acamprosate; Acamprosate calcium[2] Acamprosate calcium ,
Acamprosate 💬 		[5] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬 		[21] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[3] 2, 6, 206 💬
4 Acetate [1] Acetate---[52] 1, 2, 6, 10, 11, 13, 22, 35, 40, 46, 49, 51, 60, 63, 64, 65, 66, 67, 70, 71, 73, 75, 76, 77, 78, 79, 81, 83, 85, 86, 88, 89, 90, 96, 97, 113, 145, 156, 158, 162, 171, 206, 222, 223, 224, 225, 227, 235, 251, 265, 298, 299 💬
5 Acetylcarnitine [2] Acetyl-l-carnitine; Acetylcarnitine---[3] 2, 97, 265 💬
6 Acetylcysteine [4] Acetylcysteine; N acetyl cysteine; N-Acetyl cysteine; N-acetylcysteine[1] Acetylcysteine 💬 --[25] 2, 6, 13, 19, 20, 21, 34, 49, 51, 53, 58, 63, 85, 90, 94, 97, 111, 164, 193, 233, 296, 298, 299, 303, 337 💬
7 Aldesleukin [2] Aldesleukin; ILT-101[1] Aldesleukin 💬 [3] IL2RA,
IL2RB,
IL2RG 💬 		[14] Cytokine-cytokine receptor interaction, Endocytosis, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, Inflammatory bowel disease, JAK-STAT signaling pathway, Measles, PI3K-Akt signaling pathway, Pathways in cancer, Primary immunodeficiency, Th1 and Th2 cell differentiation, Th17 cell differentiation, Transcriptional misregulation in cancer, Viral protein interaction with cytokine and cytokine receptor 💬[5] 2, 49, 65, 96, 97 💬
8 Amantadine [3] Amantadine; AMANTADINE HYDROCHLORIDE; Amantadine sulfate[2] Amantadine hydrochloride ,
Amantadine 💬 		[5] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬 		[21] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[5] 2, 6, 8, 13, 127 💬
9 Ambroxol [2] Ambroxol; AMBROXOL HYDROCHLORIDE[2] Ambroxol hydrochloride ,
Ambroxol 💬 		--[3] 2, 6, 19 💬
10 AMT-162 [1] AMT-162---[1] 2 💬
11 Anakinra [1] Anakinra[1] Anakinra 💬 [2] IL1R1,
IL1R2 💬 		[15] Amoebiasis, Cytokine-cytokine receptor interaction, Fluid shear stress and atherosclerosis, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Inflammatory mediator regulation of TRP channels, MAPK signaling pathway, NF-kappa B signaling pathway, Osteoclast differentiation, Pathogenic Escherichia coli infection, Prostate cancer, Shigellosis, Th17 cell differentiation, Transcriptional misregulation in cancer 💬[22] 2, 13, 15, 19, 28, 37, 41, 46, 49, 50, 54, 56, 57, 84, 86, 97, 106, 107, 149, 153, 266, 299 💬
12 ANX-005 [0] ---[3] 2, 8, 61 💬
13 AP-101 [1] AP-101---[1] 2 💬
14 Apple [1] Apple---[3] 2, 58, 70 💬
15 Arginine [1] Arginine[3] Arginine hydrochloride ,
Arginine ,
Arginine hydrochloride 💬 		--[16] 2, 21, 46, 57, 58, 67, 72, 96, 97, 98, 113, 210, 223, 225, 251, 299 💬
16 ARGX-119 [1] ARGX-119---[3] 2, 3, 12 💬
17 Arimoclomol [2] ARIMOCLOMOL; Arimoclomol citrate[2] Arimoclomol ,
Arimoclomol citrate 💬 		--[3] 2, 15, 19 💬
18 Arundic acid [1] Arundic Acid[1] Arundic acid 💬 --[1] 2 💬
19 Astaxanthin [1] Astaxanthin---[2] 2, 280 💬
20 Atropine [1] Atropine[2] Atropine ,
Atropine sulfate 💬 		[5] CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5 💬 		[14] Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬[1] 2 💬
21 Baclofen [1] Baclofen[1] Baclofen 💬 [2] GABBR1,
GABBR2 💬 		[8] Estrogen signaling pathway, GABAergic synapse, GnRH secretion, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Taste transduction, cAMP signaling pathway 💬[8] 2, 10, 13, 18, 65, 70, 149, 206 💬
22 Baricitinib [1] BARICITINIB[1] Baricitinib 💬 [2] JAK1,
JAK2 💬 		[37] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease, Efferocytosis, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Hormone signaling, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Necroptosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬[24] 2, 13, 40, 41, 46, 49, 50, 51, 53, 54, 56, 63, 65, 84, 93, 107, 135, 162, 265, 268, 269, 300, 325, 345 💬
23 Barium [1] Barium---[5] 2, 6, 19, 97, 98 💬
24 Basiliximab [1] Basiliximab[1] Basiliximab 💬 [1] IL2RA 💬 [11] Cytokine-cytokine receptor interaction, Endocytosis, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, JAK-STAT signaling pathway, Measles, PI3K-Akt signaling pathway, Pathways in cancer, Th1 and Th2 cell differentiation, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[5] 2, 50, 97, 222, 228 💬
25 Betamethasone [1] Betamethasone[6] Betamethasone ,
Betamethasone sodium phosphate ,
Betamethasone valerate ,
Betamethasone acetate ,
Betamethasone dipropionate ,
Betamethasone benzoate 💬 		[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[9] 2, 28, 46, 56, 65, 83, 90, 96, 235 💬
26 Biotin [4] Biotin; Biotina; D-BIOTIN; Vitamin B7[1] Biotin 💬 --[6] 2, 8, 10, 13, 14, 20 💬
27 BLZ-945 [1] Sotuletinib---[1] 2 💬
28 Bosutinib [1] BOSUTINIB[2] Bosutinib ,
Bosutinib hydrate 💬 		[2] ABL1,
SRC 💬 		[50] Adherens junction, Axon guidance, Bacterial invasion of epithelial cells, Bladder cancer, C-type lectin receptor signaling pathway, Cell cycle, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Chronic myeloid leukemia, Endocytosis, Epithelial cell signaling in Helicobacter pylori infection, ErbB signaling pathway, Estrogen signaling pathway, Fluid shear stress and atherosclerosis, Focal adhesion, GABAergic synapse, Gap junction, GnRH signaling pathway, Hepatitis B, Herpes simplex virus 1 infection, Hormone signaling, Human cytomegalovirus infection, IgSF CAM signaling, Inflammatory mediator regulation of TRP channels, Integrin signaling, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, MicroRNAs in cancer, Mitophagy - animal, Neurotrophin signaling pathway, Neutrophil extracellular trap formation, Oxytocin signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Platelet activation, Prolactin signaling pathway, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis, Thyroid hormone signaling pathway, Tight junction, Tuberculosis, VEGF signaling pathway, Viral carcinogenesis, Viral myocarditis, Yersinia infection 💬[2] 2, 67 💬
29 Botulinum toxin type A [5] Botulinum toxin A; BOTULINUM TOXIN TYPE A; IncobotulinumtoxinA; Onabotulinumtoxin A; OnabotulinumtoxinA[4] Botulinum toxin type A ,
OnabotulinumtoxinA ,
AbobotulinumtoxinA ,
Incobotulinumtoxin A 💬 		[1] SNAP25 💬 [2] Insulin secretion, Synaptic vesicle cycle 💬[13] 2, 5, 6, 7, 13, 15, 17, 47, 70, 113, 149, 171, 226 💬
30 Botulinum toxin type B [1] Botulinum toxin type B[1] RimabotulinumtoxinB 💬 [1] SNAP25 💬 [2] Insulin secretion, Synaptic vesicle cycle 💬[3] 2, 6, 51 💬
31 Butylphthalide [2] 3-N-butylphthalide; Butylphthalide---[4] 2, 6, 17, 22 💬
32 Caffeine [1] Caffeine[2] Caffeine ,
Caffeine citrate 💬 		[11] ADORA1,
ADORA2A,
PDE1B,
PDE2A,
PDE3A,
PDE3B,
PDE4A,
PDE4B,
PDE4C,
PDE4D,
PDE5A 💬 		[22] Alcoholism, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Glucagon signaling pathway, Insulin signaling pathway, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Parkinson disease, Progesterone-mediated oocyte maturation, Purine metabolism, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Taste transduction, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[8] 2, 6, 13, 21, 46, 96, 97, 265 💬
33 Calcium [1] Calcium---[39] 2, 3, 6, 13, 15, 19, 46, 48, 49, 51, 53, 56, 62, 67, 68, 71, 74, 75, 79, 84, 90, 93, 94, 95, 96, 97, 156, 186, 214, 215, 222, 224, 235, 256, 265, 271, 274, 298, 299 💬
34 Capsaicin [1] Capsaicin[1] Capsaicin 💬 [1] TRPV1 💬 [2] Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬[5] 2, 6, 19, 86, 226 💬
35 Ceftriaxone [1] Ceftriaxone[2] Ceftriaxone sodium ,
Ceftriaxone 💬 		--[4] 2, 6, 97, 299 💬
36 Celecoxib [1] CELECOXIB[1] Celecoxib 💬 [1] PTGS2 💬 [22] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Efferocytosis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[14] 2, 3, 6, 13, 34, 46, 70, 89, 96, 97, 107, 161, 171, 271 💬
37 Censavudine [1] CENSAVUDINE[1] Censavudine 💬 --[3] 2, 127, 325 💬
38 Cimetidine [1] Cimetidine[2] Cimetidine ,
Cimetidine hydrochloride 💬 		[1] HRH2 💬 [4] Calcium signaling pathway, Gastric acid secretion, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction 💬[2] 2, 254 💬
39 Ciprofloxacin [2] Ciprofloxacin; CIPROFLOXACIN HYDROCHLORIDE[3] Ciprofloxacin ,
Ciprofloxacin hydrochloride ,
Ciprofloxacin lactate 💬 		--[6] 2, 46, 60, 96, 97, 299 💬
40 Clenbuterol [2] Clenbuterol; CLENBUTEROL HYDROCHLORIDE[2] Clenbuterol hydrochloride ,
Clenbuterol 💬 		[1] ADRB2 💬 [11] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[6] 1, 2, 6, 57, 113, 256 💬
41 CNM-Au8 [1] CNM-Au8---[2] 2, 13 💬
42 Colchicine [2] COLCHICINA; Colchicine[1] Colchicine 💬 [9] TUBB,
TUBB1,
TUBB2A,
TUBB2B,
TUBB3,
TUBB4A,
TUBB4B,
TUBB6,
TUBB8 💬 		[12] Alzheimer disease, Amyotrophic lateral sclerosis, Gap junction, Huntington disease, IgSF CAM signaling, Motor proteins, Parkinson disease, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Phagocytosis, Prion disease, Salmonella infection 💬[9] 2, 42, 46, 50, 56, 93, 97, 210, 266 💬
43 Copper [1] Copper---[4] 2, 169, 170, 171 💬
44 Corticotropin [3] ACTH; Adrenocorticotropic Hormone; Corticotropin[2] Corticotropin ,
Corticotropin, repository 💬 		[1] MC2R 💬 [6] Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome, Hormone signaling, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[10] 2, 13, 46, 75, 78, 81, 84, 145, 205, 222 💬
45 Creatine [3] Acetic acid; Creatine; Creatine Monohydrate---[18] 1, 2, 3, 5, 6, 8, 13, 15, 21, 46, 49, 50, 97, 113, 156, 201, 256, 337 💬
46 Creatinine [1] Creatinine[1] Creatinine 💬 --[9] 2, 46, 49, 60, 66, 70, 96, 97, 222 💬
47 Crizotinib [1] Crizotinib[1] Crizotinib 💬 [1] ALK 💬 [3] Non-small cell lung cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways in cancer 💬[2] 2, 34 💬
48 Curcumin [1] Curcumin---[12] 2, 13, 34, 36, 46, 67, 74, 94, 96, 97, 139, 299 💬
49 Cycloserine [1] Cycloserine[1] Cycloserine 💬 --[1] 2 💬
50 Darifenacin [1] Darifenacin[2] Darifenacin hydrobromide ,
Darifenacin 💬 		[1] CHRM3 💬 [12] Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction 💬[4] 2, 6, 13, 26 💬
51 Darunavir [1] Darunavir[3] Darunavir ,
Darunavir ethanolate ,
Darunavir propylene glycolate 💬 		--[1] 2 💬
52 Dazucorilant [1] Dazucorilant[1] Dazucorilant 💬 [1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[1] 2 💬
53 Debamestrocel [1] Debamestrocel---[1] 2 💬
54 Deferiprone [1] DEFERIPRONE[1] Deferiprone 💬 --[7] 2, 6, 18, 121, 122, 139, 233 💬
55 Dexmedetomidine [4] DEXMEDETOMIDINA; Dexmedetomidine; DEXMEDETOMIDINE HYDROCHLORIDE; Imidazole[2] Dexmedetomidine ,
Dexmedetomidine hydrochloride 💬 		[3] ADRA2A,
ADRA2B,
ADRA2C 💬 		[4] Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬[15] 2, 4, 6, 21, 22, 34, 46, 70, 107, 113, 171, 212, 215, 226, 280 💬
56 Dexpramipexole [2] Dexpramipexole; Dexpramipexole Dihydrochloride[2] Dexpramipexole ,
Dexpramipexole dihydrochloride 💬 		[5] DRD1,
DRD2,
DRD3,
DRD4,
DRD5 💬 		[13] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 2 💬
57 Dextran [2] Dextran; DEXTRAN SULFATE SODIUM[5] Dextran 1 ,
Dextran sulfate sodium ,
Dextran 40 ,
Dextran 70 ,
Dextran 75 💬 		[2] LIPC,
LPL 💬 		[4] Alzheimer disease, Cholesterol metabolism, Glycerolipid metabolism, PPAR signaling pathway 💬[5] 2, 62, 79, 96, 97 💬
58 Dextromethorphan [2] Dextromethorphan; DEXTROMETHORPHAN HYDROBROMIDE[3] Dextromethorphan hydrobromide ,
Dextromethorphan ,
Dextromethorphan polistirex 💬 		[6] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D,
SIGMAR1 💬 		[21] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[10] 2, 6, 8, 13, 21, 46, 85, 96, 97, 156 💬
59 Digoxin [1] Digoxin[1] Digoxin 💬 [4] ATP1A1,
ATP1A2,
ATP1A3,
ATP1A4 💬 		[19] Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Aldosterone-regulated sodium reabsorption, Bile secretion, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cytoskeleton in muscle cells, Endocrine and other factor-regulated calcium reabsorption, Gastric acid secretion, Insulin secretion, Mineral absorption, Pancreatic secretion, Protein digestion and absorption, Proximal tubule bicarbonate reclamation, Salivary secretion, Thyroid hormone signaling pathway, Thyroid hormone synthesis, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[7] 2, 8, 46, 57, 65, 67, 210 💬
60 DNL343 [1] DNL343---[1] 2 💬
61 Dolutegravir [1] Dolutegravir[2] Dolutegravir ,
Dolutegravir sodium 💬 		--[3] 2, 26, 265 💬
62 Dronabinol [3] DELTA-9-TETRAHYDROCANNABINOL; Dronabinol; Tetrahydrocannabinol[1] Dronabinol 💬 [2] CNR1,
CNR2 💬 		[4] Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬[5] 2, 13, 46, 271, 298 💬
63 Dutasteride [2] Dutasterida; Dutasteride[1] Dutasteride 💬 [2] SRD5A1,
SRD5A2 💬 		[2] Prostate cancer, Steroid hormone biosynthesis 💬[2] 1, 2 💬
64 Edaravone [3] EDARAVONE; Methylphenylpyrazolone; Norphenazone[1] Edaravone 💬 --[3] 2, 6, 22 💬
65 Enoxacin [1] Enoxacin[1] Enoxacin 💬 --[1] 2 💬
66 Eperisone [1] EPERISONE[2] Eperisone hydrochloride ,
Eperisone 💬 		--[1] 2 💬
67 EPI-589 [1] EPI-589---[2] 2, 6 💬
68 Erythromycin [1] Erythromycin[7] Erythromycin ,
Erythromycin estolate ,
Erythromycin ethylsuccinate ,
Erythromycin lactobionate ,
Erythromycin stearate ,
Erythromycin gluceptate ,
Erythromycin thiocyanate 💬 		--[6] 2, 6, 36, 164, 228, 291 💬
69 Erythropoietin [3] Epoetin alfa; Erythropoietin; RhEPO[4] Epoetin alfa ,
Epoetin epsilon ,
Epoetin theta ,
Epoetin zeta 💬 		[1] EPOR 💬 [7] Cytokine-cytokine receptor interaction, Efferocytosis, Hematopoietic cell lineage, Hormone signaling, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer 💬[11] 2, 6, 13, 18, 22, 47, 61, 63, 70, 95, 96 💬
70 Escitalopram [3] Citalopram; Escitalopram; Escitalopram oxalate[2] Escitalopram oxalate ,
Escitalopram 💬 		[1] SLC6A4 💬 [3] Neuroactive ligand signaling, Serotonergic synapse, Synaptic vesicle cycle 💬[5] 2, 6, 13, 46, 77 💬
71 Esketamine [3] Esketamine; Esketamine hydrochloride; Ketamine[2] Esketamine ,
Esketamine hydrochloride 💬 		[5] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬 		[21] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[7] 2, 4, 6, 70, 96, 97, 156 💬
72 Ezogabine [2] Ezogabine; RETIGABINE[1] Ezogabine 💬 [5] KCNQ1,
KCNQ2,
KCNQ3,
KCNQ4,
KCNQ5 💬 		[7] Adrenergic signaling in cardiomyocytes, Cholinergic synapse, Gastric acid secretion, IgSF CAM signaling, Pancreatic secretion, Protein digestion and absorption, Vibrio cholerae infection 💬[2] 2, 144 💬
73 Fasudil [2] Fasudil; FASUDIL HYDROCHLORIDE[2] Fasudil hydrochloride ,
Fasudil 💬 		[2] ROCK1,
ROCK2 💬 		[25] Adherens junction, Axon guidance, Cadherin signaling, Chemokine signaling pathway, Focal adhesion, Human cytomegalovirus infection, Leukocyte transendothelial migration, Lipid and atherosclerosis, MicroRNAs in cancer, Oxytocin signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Platelet activation, Proteoglycans in cancer, Regulation of actin cytoskeleton, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, TGF-beta signaling pathway, Tight junction, Vascular smooth muscle contraction, Wnt signaling pathway, Yersinia infection, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[5] 2, 5, 6, 7, 51 💬
74 Febuxostat [1] Febuxostat[2] Febuxostat ,
Febuxostat hydrate 💬 		[1] XDH 💬 [4] Caffeine metabolism, Drug metabolism - other enzymes, Peroxisome, Purine metabolism 💬[5] 2, 6, 13, 67, 97 💬
75 Fecal microbiota [3] Fecal microbial transplantation; Fecal microbiota; Fecal Microbiota Transplantation---[14] 2, 6, 13, 49, 63, 66, 93, 94, 96, 97, 99, 222, 271, 298 💬
76 Fig [1] Fig---[1] 2 💬
77 Filgrastim [4] Filgrastim; G-CSF; Gcsf; Granulocyte Colony Stimulating Factor[1] Filgrastim 💬 [1] CSF3R 💬 [5] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer 💬[30] 2, 6, 13, 25, 26, 28, 34, 35, 38, 40, 41, 42, 45, 46, 47, 49, 51, 60, 62, 63, 65, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬
78 Flutemetamol [1] Flutemetamol---[6] 2, 5, 6, 7, 17, 127 💬
79 Fosigotifator [2] ABBV-CLS-7262; Fosigotifator[1] Fosigotifator 💬 [5] EIF2B1,
EIF2B2,
EIF2B3,
EIF2B4,
EIF2B5 💬 		[2] Herpes simplex virus 1 infection, Integrated stress response (ISR) signaling pathway 💬[2] 2, 308 💬
80 Galunisertib [1] Galunisertib[1] Galunisertib 💬 [1] TGFBR1 💬 [23] AGE-RAGE signaling pathway in diabetic complications, Adherens junction, Apelin signaling pathway, Cellular senescence, Chagas disease, Chronic myeloid leukemia, Colorectal cancer, Cytokine-cytokine receptor interaction, Diabetic cardiomyopathy, Endocytosis, FoxO signaling pathway, Gastric cancer, Hepatitis B, Hepatocellular carcinoma, Hippo signaling pathway, Human T-cell leukemia virus 1 infection, MAPK signaling pathway, Osteoclast differentiation, Pancreatic cancer, Pathways in cancer, Relaxin signaling pathway, TGF-beta signaling pathway, Th17 cell differentiation 💬[1] 2 💬
81 GDC-0134 [1] GDC-0134---[1] 2 💬
82 Glatiramer [2] Glatiramer; Glatiramer Acetate[1] Glatiramer acetate 💬 [20] HLA-A,
HLA-B,
HLA-C,
HLA-DMA,
HLA-DMB,
HLA-DOA,
HLA-DOB,
HLA-DPA1,
HLA-DPB1,
HLA-DQA1,
HLA-DQA2,
HLA-DQB1,
HLA-DRA,
HLA-DRB1,
HLA-DRB3,
HLA-DRB4,
HLA-DRB5,
HLA-E,
HLA-F,
HLA-G 💬 		[32] Allograft rejection, Antigen processing and presentation, Asthma, Autoimmune thyroid disease, Cell adhesion molecule (CAM) interaction, Cellular senescence, Endocytosis, Epstein-Barr virus infection, Graft-versus-host disease, Hematopoietic cell lineage, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Inflammatory bowel disease, Influenza A, Intestinal immune network for IgA production, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Natural killer cell mediated cytotoxicity, Phagocytosis, Rheumatoid arthritis, Staphylococcus aureus infection, Systemic lupus erythematosus, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Viral carcinogenesis, Viral myocarditis 💬[4] 2, 13, 96, 156 💬
83 Gold [1] Gold---[71] 2, 5, 6, 11, 13, 17, 19, 21, 22, 28, 34, 35, 46, 49, 50, 53, 54, 56, 57, 58, 60, 63, 64, 65, 66, 68, 71, 75, 76, 77, 79, 84, 85, 86, 88, 91, 93, 95, 96, 97, 98, 107, 113, 127, 137, 158, 162, 167, 171, 193, 206, 215, 218, 222, 223, 224, 226, 227, 228, 230, 235, 271, 291, 294, 296, 298, 299, 310, 318, 331, 340 💬
84 Guanabenz [1] GUANABENZ[2] Guanabenz acetate ,
Guanabenz 💬 		[3] ADRA2A,
ADRA2B,
ADRA2C 💬 		[4] Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬[2] 2, 13 💬
85 Ibudilast [1] Ibudilast[1] Ibudilast 💬 [8] CYSLTR1,
PDE3A,
PDE3B,
PDE4A,
PDE4B,
PDE4C,
PDE4D,
PTGIR 💬 		[15] Apelin signaling pathway, Calcium signaling pathway, Glucagon signaling pathway, Insulin signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Parathyroid hormone synthesis, secretion and action, Platelet activation, Progesterone-mediated oocyte maturation, Purine metabolism, Regulation of lipolysis in adipocytes, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[2] 2, 13 💬
86 Icerguastat [1] Icerguastat---[1] 2 💬
87 Inosine [1] Inosine[1] Inosine 💬 --[5] 2, 6, 13, 17, 122 💬
88 IPL-344 [0] ---[1] 2 💬
89 ISIS-333611 [0] ---[1] 2 💬
90 Itraconazole [1] Itraconazole[1] Itraconazole 💬 --[13] 2, 3, 6, 46, 65, 67, 96, 97, 137, 158, 227, 299, 309 💬
91 L-arginine [1] L-arginine---[10] 2, 21, 46, 67, 96, 97, 98, 113, 223, 299 💬
92 Lacosamide [1] Lacosamide[1] Lacosamide 💬 [2] SCN3A,
SCN9A 💬 		[1] Taste transduction 💬[4] 2, 46, 149, 298 💬
93 Lactose [2] Lactose; Lactose monohydrate[2] Anhydrous lactose ,
Lactose hydrate 💬 		--[8] 2, 6, 13, 21, 97, 107, 228, 310 💬
94 Lamivudine [1] Lamivudine[1] Lamivudine 💬 --[10] 2, 26, 42, 46, 49, 135, 156, 223, 265, 325 💬
95 Lenograstim [2] G-CSF; Lenograstim[1] Lenograstim 💬 [1] CSF3R 💬 [5] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer 💬[8] 2, 13, 16, 18, 19, 57, 65, 97 💬
96 Lenzumestrocel [1] Lenzumestrocel---[1] 2 💬
97 Leuprolide [2] Leuprolide; Leuprorelin[3] Leuprolide acetate ,
Leuprolide ,
Leuprolide mesylate 💬 		[1] GNRHR 💬 [3] GnRH signaling pathway, Hormone signaling, Neuroactive ligand-receptor interaction 💬[5] 1, 2, 3, 51, 76 💬
98 Levetiracetam [1] Levetiracetam[1] Levetiracetam 💬 [1] SV2A 💬 [1] ECM-receptor interaction 💬[7] 2, 4, 6, 13, 34, 149, 307 💬
99 Levosimendan [1] LEVOSIMENDAN[1] Levosimendan 💬 [2] PDE3A,
PDE3B 💬 		[10] Apelin signaling pathway, Glucagon signaling pathway, Insulin signaling pathway, Morphine addiction, Progesterone-mediated oocyte maturation, Purine metabolism, Regulation of lipolysis in adipocytes, Renin secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[2] 2, 57 💬
100 Linoleic acid [1] Linoleic acid---[4] 2, 5, 13, 299 💬
101 Lipoic acid [3] Alpha Lipoic Acid; ALPHA-LIPOIC ACID; Lipoic acid[1] Thioctic acid 💬 --[6] 2, 5, 13, 14, 20, 97 💬
102 Lithium carbonate [1] LITHIUM CARBONATE[1] Lithium carbonate 💬 --[6] 2, 13, 17, 18, 127, 310 💬
103 Lithium citrate [1] LITHIUM CITRATE[1] Lithium citrate 💬 --[1] 2 💬
104 Masitinib [2] Masitinib; Masitinib mesylate[1] Masitinib 💬 [1] KIT 💬 [11] Acute myeloid leukemia, Breast cancer, Central carbon metabolism in cancer, Hematopoietic cell lineage, MAPK signaling pathway, Melanogenesis, PI3K-Akt signaling pathway, Pathways in cancer, Phospholipase D signaling pathway, Rap1 signaling pathway, Ras signaling pathway 💬[6] 2, 5, 6, 13, 46, 96 💬
105 Mecobalamin [2] Mecobalamin; Methylcobalamin[1] Mecobalamin 💬 --[3] 2, 70, 302 💬
106 Megestrol [1] Megestrol[1] Megestrol 💬 [1] PGR 💬 [5] Breast cancer, Chemical carcinogenesis - receptor activation, Estrogen signaling pathway, Oocyte meiosis, Progesterone-mediated oocyte maturation 💬[2] 2, 76 💬
107 Melatonin [1] Melatonin[1] Melatonin 💬 [2] MTNR1A,
MTNR1B 💬 		[2] Circadian entrainment, Neuroactive ligand-receptor interaction 💬[18] 2, 6, 8, 13, 37, 46, 49, 72, 78, 86, 90, 96, 97, 145, 149, 159, 202, 265 💬
108 Memantine [2] Memantine; MEMANTINE HYDROCHLORIDE[2] Memantine hydrochloride ,
Memantine 💬 		[5] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬 		[21] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[8] 2, 6, 8, 13, 49, 127, 205, 206 💬
109 Metformin [4] Metformin; Metformin Hydrochloride; Metformina; Metformine[2] Metformin hydrochloride ,
Metformin 💬 		[2] PRKAA1,
PRKAA2 💬 		[20] AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬[31] 2, 6, 8, 13, 46, 49, 60, 65, 66, 67, 74, 75, 77, 81, 84, 85, 86, 97, 113, 127, 158, 206, 218, 222, 225, 233, 265, 285, 298, 299, 301 💬
110 Methane [1] Methane---[2] 2, 97 💬
111 Methylprednisolone [3] Methylprednisolon; Methylprednisolone; METHYLPREDNISOLONE ACETATE[2] Methylprednisolone ,
Methylprednisolone acetate 💬 		[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[51] 2, 6, 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 95, 96, 97, 111, 127, 145, 162, 164, 211, 222, 223, 224, 271, 283, 284, 285, 296, 300 💬
112 Mexiletine [2] Mexiletine; Mexiletine hydrochloride[2] Mexiletine hydrochloride ,
Mexiletine 💬 		[6] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN8A,
SCN9A 💬 		[5] Adrenergic signaling in cardiomyocytes, Cadherin signaling, Dopaminergic synapse, IgSF CAM signaling, Taste transduction 💬[6] 1, 2, 10, 113, 114, 115 💬
113 Midazolam [1] Midazolam[3] Midazolam ,
Midazolam hydrochloride ,
Midazolam maleate 💬 		[16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬 		[9] Cadherin signaling, GABAergic synapse, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[14] 2, 3, 6, 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬
114 Minocycline [2] Minocycline; Minocycline Hydrochloride[2] Minocycline hydrochloride ,
Minocycline 💬 		--[14] 2, 6, 8, 13, 46, 85, 90, 94, 97, 162, 201, 206, 280, 299 💬
115 Moxifloxacin [2] Moxifloxacin; Moxifloxacin hydrochloride[3] Moxifloxacin hydrochloride ,
Moxifloxacin ,
Moxifloxacin hydrochloride monohydrate 💬 		--[10] 2, 6, 46, 49, 85, 86, 113, 226, 240, 299 💬
116 Mycophenolate mofetil [1] Mycophenolate mofetil[2] Mycophenolate mofetil ,
Mycophenolate mofetil hydrochloride 💬 		[2] IMPDH1,
IMPDH2 💬 		[2] Drug metabolism - other enzymes, Purine metabolism 💬[38] 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 46, 49, 51, 53, 57, 60, 61, 62, 63, 65, 66, 93, 95, 96, 118, 162, 164, 222, 223, 224, 226, 234, 283, 284, 285, 300 💬
117 Nerandomilast [1] Nerandomilast[1] Nerandomilast 💬 [1] PDE4B 💬 [4] Morphine addiction, Parathyroid hormone synthesis, secretion and action, Purine metabolism, cAMP signaling pathway 💬[3] 2, 51, 85 💬
118 Nerve Growth Factor [1] Nerve Growth Factor---[5] 2, 3, 18, 53, 90 💬
119 Nicotinamide [2] Niacinamide; NICOTINAMIDE[1] Niacinamide 💬 --[19] 2, 5, 6, 7, 8, 17, 18, 21, 46, 49, 60, 63, 65, 85, 97, 107, 162, 191, 302 💬
120 Nicotinamide riboside [2] Nicotinamide Riboside; Nicotinamide Riboside Chloride---[14] 2, 5, 6, 7, 8, 17, 18, 21, 49, 60, 65, 85, 97, 191 💬
121 Olanzapine [1] OLANZAPINE[2] Olanzapine ,
Olanzapine pamoate 💬 		[11] ADRA1A,
ADRA1B,
ADRA1D,
DRD2,
DRD3,
DRD4,
HRH1,
HTR2A,
HTR2B,
HTR2C,
HTR6 💬 		[18] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Alcoholism, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Inflammatory mediator regulation of TRP channels, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Salivary secretion, Serotonergic synapse, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[2] 2, 8 💬
122 Olesoxime [1] Olesoxime[1] Olesoxime 💬 --[3] 2, 3, 13 💬
123 Oxaloacetic acid [1] Oxaloacetic Acid---[1] 2 💬
124 Ozanezumab [1] Ozanezumab[1] Ozanezumab 💬 [1] RTN4 💬 [1] Alzheimer disease 💬[1] 2 💬
125 Pegcetacoplan [1] Pegcetacoplan[1] Pegcetacoplan 💬 [1] C3 💬 [18] Alcoholic liver disease, Chagas disease, Complement and coagulation cascades, Coronavirus disease, Herpes simplex virus 1 infection, Integrin signaling, Kaposi sarcoma-associated herpesvirus infection, Legionellosis, Leishmaniasis, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Phagocytosis, Shigellosis, Staphylococcus aureus infection, Systemic lupus erythematosus, Tuberculosis, Viral carcinogenesis 💬[4] 2, 61, 62, 223 💬
126 Perampanel [1] PERAMPANEL[2] Perampanel ,
Perampanel hydrate 💬 		[4] GRIA1,
GRIA2,
GRIA3,
GRIA4 💬 		[17] Amphetamine addiction, Amyotrophic lateral sclerosis, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term depression, Long-term potentiation, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Retrograde endocannabinoid signaling, Spinocerebellar ataxia, Transcriptional misregulation in cancer, cAMP signaling pathway 💬[3] 2, 6, 144 💬
127 Perflutren [1] Perflutren[1] Perflutren 💬 --[2] 2, 70 💬
128 Phenylbutyric acid [2] PHENYLBUTYRATE; Sodium phenylbutyrate[1] Sodium phenylbutyrate 💬 --[5] 2, 3, 8, 18, 251 💬
129 Pimozide [1] Pimozide[1] Pimozide 💬 [2] ADRA2A,
DRD2 💬 		[11] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 2 💬
130 Pioglitazone [1] Pioglitazone[2] Pioglitazone hydrochloride ,
Pioglitazone 💬 		[1] PPARG 💬 [12] AMPK signaling pathway, Efferocytosis, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬[17] 2, 6, 13, 15, 20, 46, 49, 65, 67, 81, 86, 96, 223, 229, 265, 298, 299 💬
131 Pleconaril [1] PLECONARIL[1] Pleconaril 💬 --[1] 2 💬
132 Pramipexole [3] Pramipexol; Pramipexole; PRAMIPEXOLE DIHYDROCHLORIDE MONOHYDRATE[2] Pramipexole dihydrochloride ,
Pramipexole 💬 		[3] DRD2,
DRD3,
DRD4 💬 		[10] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[4] 2, 6, 20, 74 💬
133 Prednisone [2] PREDNISONA; Prednisone[1] Prednisone 💬 [1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[58] 2, 11, 13, 14, 18, 19, 26, 28, 35, 40, 41, 42, 43, 44, 45, 46, 48, 49, 50, 51, 53, 60, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 90, 93, 95, 96, 97, 113, 127, 145, 162, 164, 205, 222, 223, 224, 228, 251, 269, 283, 284, 285, 288, 299, 300, 303, 307, 331 💬
134 Pridopidine [2] Pridopidine; PRIDOPIDINE HYDROCHLORIDE[2] Pridopidine ,
Pridopidine hydrochloride 💬 		[1] DRD2 💬 [10] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[3] 2, 6, 8 💬
135 Primidone [1] Primidone[1] Primidone 💬 --[2] 2, 113 💬
136 Prosetin [1] Prosetin---[1] 2 💬
137 Psilocybin [2] Psilocybin; Psilocybine[1] Psilocybin 💬 [1] HTR2A 💬 [6] Calcium signaling pathway, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Serotonergic synapse 💬[5] 2, 6, 13, 149, 206 💬
138 Pterostilbene [1] Pterostilbene---[1] 2 💬
139 Pyrimethamine [1] Pyrimethamine[1] Pyrimethamine 💬 --[4] 2, 4, 19, 65 💬
140 Pyruvic acid [1] SODIUM PYRUVATE---[6] 2, 21, 67, 85, 299, 318 💬
141 Quinidine [2] Quinidine; Quinidine Sulfate[4] Quinidine gluconate ,
Quinidine polygalacturonate ,
Quinidine sulfate ,
Quinidine 💬 		[6] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN8A,
SCN9A 💬 		[5] Adrenergic signaling in cardiomyocytes, Cadherin signaling, Dopaminergic synapse, IgSF CAM signaling, Taste transduction 💬[3] 2, 8, 13 💬
142 Rabeprazole [1] Rabeprazole[2] Rabeprazole sodium ,
Rabeprazole 💬 		[2] ATP4A,
ATP4B 💬 		[3] Collecting duct acid secretion, Gastric acid secretion, Oxidative phosphorylation 💬[3] 2, 6, 51 💬
143 RAG-17 [1] RAG-17---[1] 2 💬
144 Ranolazine [1] Ranolazine[2] Ranolazine ,
Ranolazine hydrochloride 💬 		--[8] 2, 57, 58, 86, 96, 97, 113, 114 💬
145 Rasagiline [2] Rasagiline; Rasagiline mesylate[3] Rasagiline mesylate ,
Rasagiline ,
Rasagiline tartrate 💬 		[1] MAOB 💬 [13] Alcoholism, Amphetamine addiction, Arginine and proline metabolism, Cocaine addiction, Dopaminergic synapse, Drug metabolism - cytochrome P450, Glycine, serine and threonine metabolism, Histidine metabolism, Parkinson disease, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬[4] 2, 5, 6, 17 💬
146 Ravulizumab [1] RAVULIZUMAB[1] Ravulizumab 💬 [1] C5 💬 [11] Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Regulation of actin cytoskeleton, Staphylococcus aureus infection, Systemic lupus erythematosus 💬[8] 2, 11, 13, 50, 62, 66, 109, 224 💬
147 Reldesemtiv [2] CK-2127107; Reldesemtiv[1] Reldesemtiv 💬 [3] TNNC2,
TNNI2,
TNNT3 💬 		[3] Calcium signaling pathway, Cytoskeleton in muscle cells, Motor proteins 💬[2] 2, 3 💬
148 Resveratrol [2] Resveratrol; Trans-Resveratrol---[10] 2, 6, 8, 18, 46, 57, 89, 97, 113, 299 💬
149 Ribavirin [1] RIBAVIRIN[1] Ribavirin 💬 --[2] 2, 96 💬
150 Riluzole [1] Riluzole[1] Riluzole 💬 [14] GRIA1,
GRIA2,
GRIA3,
GRIA4,
GRIK1,
GRIK2,
GRIK3,
GRIK4,
GRIK5,
GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬 		[24] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term depression, Long-term potentiation, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Retrograde endocannabinoid signaling, Spinocerebellar ataxia, Systemic lupus erythematosus, Transcriptional misregulation in cancer, cAMP signaling pathway 💬[9] 2, 3, 5, 8, 13, 17, 18, 203, 206 💬
151 Ritonavir [1] Ritonavir[1] Ritonavir 💬 --[3] 2, 86, 265 💬
152 SB-509 [1] SB-509---[1] 2 💬
153 Scopolamine [1] Scopolamine[2] Scopolamine ,
Scopolamine hydrobromide 💬 		[5] CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5 💬 		[14] Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬[1] 2 💬
154 Serine [2] L-Serine; Serine[1] Serine 💬 --[5] 2, 6, 86, 96, 222 💬
155 Serotonin [1] Serotonin---[2] 2, 164 💬
156 Sodium chloride [3] NaCl; SODIUM CHLORIDE; Sodium Chloride Solution[1] Sodium chloride 💬 --[31] 2, 6, 11, 13, 14, 22, 34, 41, 46, 50, 51, 53, 60, 65, 67, 70, 85, 96, 97, 124, 168, 193, 214, 215, 226, 227, 228, 271, 288, 298, 299 💬
157 SPG302 [1] SPG302---[1] 2 💬
158 Tacrolimus [1] Tacrolimus[2] Tacrolimus ,
Tacrolimus 💬 		[5] PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬 		[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬[37] 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 57, 60, 61, 62, 63, 65, 66, 95, 96, 97, 113, 151, 158, 164, 222, 223, 224, 226, 227, 228, 234, 283, 284, 285, 286, 299 💬
159 Talampanel [1] Talampanel[1] Talampanel 💬 [4] GRIA1,
GRIA2,
GRIA3,
GRIA4 💬 		[17] Amphetamine addiction, Amyotrophic lateral sclerosis, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term depression, Long-term potentiation, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Retrograde endocannabinoid signaling, Spinocerebellar ataxia, Transcriptional misregulation in cancer, cAMP signaling pathway 💬[2] 2, 6 💬
160 Tamoxifen [2] TAMOXIFEN; TAMOXIFEN CITRATE[2] Tamoxifen citrate ,
Tamoxifen 💬 		[2] ESR1,
ESR2 💬 		[10] Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Estrogen signaling pathway, GnRH secretion, Hormone signaling, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬[6] 2, 65, 86, 113, 227, 299 💬
161 Tauroursodeoxycholic acid [3] Tauroursodeoxycholic acid; Taurursodiol; Ursodoxicoltaurine[1] Taurursodiol 💬 --[5] 2, 28, 93, 299, 302 💬
162 Tenofovir [1] Tenofovir[1] Tenofovir 💬 --[8] 2, 6, 13, 25, 26, 93, 265, 325 💬
163 Tenofovir alafenamide [1] Tenofovir alafenamide[2] Tenofovir alafenamide ,
Tenofovir alafenamide fumarate 💬 		--[2] 2, 13 💬
164 Testosterone [1] Testosterone[1] Testosterone 💬 [1] AR 💬 [4] Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬[9] 1, 2, 3, 13, 60, 76, 78, 113, 265 💬
165 Thalidomide [1] Thalidomide[1] Thalidomide 💬 [1] TNF 💬 [66] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[22] 2, 16, 20, 28, 49, 51, 53, 56, 63, 65, 84, 85, 94, 96, 97, 117, 227, 271, 280, 298, 300, 331 💬
166 Tideglusib [1] Tideglusib---[3] 2, 5, 113 💬
167 Tirasemtiv [1] Tirasemtiv[1] Tirasemtiv 💬 --[1] 2 💬
168 Tocilizumab [2] BAT1806; Tocilizumab[1] Tocilizumab 💬 [1] IL6R 💬 [11] Coronavirus disease, Cytokine-cytokine receptor interaction, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[26] 2, 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 65, 86, 107, 149, 153, 223, 266, 271, 298, 331 💬
169 Tofacitinib [2] Tofacitinib; TOFACITINIB CITRATE[2] Tofacitinib citrate ,
Tofacitinib 💬 		[4] JAK1,
JAK2,
JAK3,
TYK2 💬 		[39] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease, Efferocytosis, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Hormone signaling, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Necroptosis, Non-small cell lung cancer, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Primary immunodeficiency, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬[23] 2, 11, 35, 38, 39, 40, 44, 46, 49, 50, 51, 53, 56, 65, 66, 84, 96, 97, 107, 110, 162, 271, 300 💬
170 Tofersen [1] Tofersen[1] Tofersen 💬 [1] SOD1 💬 [8] Amyotrophic lateral sclerosis, Chemical carcinogenesis - reactive oxygen species, Huntington disease, Longevity regulating pathway - multiple species, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Peroxisome, Prion disease 💬[1] 2 💬
171 Trametinib [1] Trametinib[2] Trametinib ,
Trametinib dimethyl sulfoxide 💬 		[2] MAP2K1,
MAP2K2 💬 		[90] Acute myeloid leukemia, Alcoholism, Alzheimer disease, Apelin signaling pathway, Apoptosis, Autophagy - animal, B cell receptor signaling pathway, Bladder cancer, Breast cancer, Cadherin signaling, Cellular senescence, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Choline metabolism in cancer, Cholinergic synapse, Chronic myeloid leukemia, Colorectal cancer, Cushing syndrome, Efferocytosis, Endometrial cancer, ErbB signaling pathway, Estrogen signaling pathway, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagosome formation, Focal adhesion, FoxO signaling pathway, Gap junction, Gastric cancer, Glioma, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatitis B, Hepatitis C, Hepatocellular carcinoma, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, IgSF CAM signaling, Influenza A, Insulin signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Long-term depression, Long-term potentiation, MAPK signaling pathway, Melanogenesis, Melanoma, MicroRNAs in cancer, Natural killer cell mediated cytotoxicity, Neurotrophin signaling pathway, Neutrophil extracellular trap formation, Non-small cell lung cancer, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Renal cell carcinoma, Salmonella infection, Serotonergic synapse, Signaling pathways regulating pluripotency of stem cells, Sphingolipid signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Thyroid cancer, Thyroid hormone signaling pathway, Toll-like receptor signaling pathway, VEGF signaling pathway, Vascular smooth muscle contraction, Yersinia infection, cAMP signaling pathway, cGMP-PKG signaling pathway, mTOR signaling pathway 💬[6] 2, 34, 58, 195, 279, 280 💬
172 Trazodone [1] Trazodone[2] Trazodone hydrochloride ,
Trazodone 💬 		[4] HTR2A,
HTR2B,
HTR2C,
SLC6A4 💬 		[7] Calcium signaling pathway, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Serotonergic synapse, Synaptic vesicle cycle 💬[1] 2 💬
173 Trehalose [2] Cabaletta; Trehalose---[4] 2, 6, 18, 113 💬
174 Tretinoin [4] All trans retinoic acid; ATRA; Tretinoin; TRETINOINA[1] Tretinoin 💬 [3] PML,
RARA,
RARB 💬 		[12] Acute myeloid leukemia, Endocytosis, Estrogen signaling pathway, Gastric cancer, Herpes simplex virus 1 infection, Influenza A, Non-small cell lung cancer, Pathways in cancer, Small cell lung cancer, Th17 cell differentiation, Transcriptional misregulation in cancer, Ubiquitin mediated proteolysis 💬[4] 2, 62, 63, 75 💬
175 Triheptanoin [1] TRIHEPTANOIN[1] Triheptanoin 💬 --[12] 2, 8, 65, 149, 156, 248, 256, 257, 317, 318, 324, 344 💬
176 Trimetazidine [2] Trimetazidine; Trimetazidine dihydrochloride[2] Trimetazidine hydrochloride ,
Trimetazidine 💬 		--[3] 2, 58, 86 💬
177 Ulefnersen [1] Ulefnersen---[1] 2 💬
178 Usnoflast [1] Usnoflast[1] Usnoflast 💬 [1] NLRP3 💬 [12] C-type lectin receptor signaling pathway, Coronavirus disease, Cytosolic DNA-sensing pathway, Influenza A, Lipid and atherosclerosis, NOD-like receptor signaling pathway, Necroptosis, Pathogenic Escherichia coli infection, Pertussis, Salmonella infection, Shigellosis, Yersinia infection 💬[1] 2 💬
179 Utreloxastat [1] Utreloxastat[1] Utreloxastat 💬 [1] ALOX15 💬 [6] Arachidonic acid metabolism, Efferocytosis, Ferroptosis, Linoleic acid metabolism, Necroptosis, Serotonergic synapse 💬[1] 2 💬
180 Verdiperstat [1] Verdiperstat[1] Verdiperstat 💬 [1] MPO 💬 [5] Acute myeloid leukemia, Drug metabolism - other enzymes, Neutrophil extracellular trap formation, Phagocytosis, Transcriptional misregulation in cancer 💬[3] 2, 17, 127 💬
181 Vitamin E [1] Vitamin E[1] Vitamin E 💬 --[12] 2, 6, 13, 19, 20, 46, 90, 96, 97, 206, 299, 317 💬
182 Water [1] Water[1] Water 💬 --[36] 2, 3, 5, 6, 13, 17, 19, 22, 35, 46, 49, 51, 53, 56, 57, 62, 63, 64, 65, 66, 67, 70, 72, 85, 86, 96, 97, 206, 215, 225, 226, 230, 240, 274, 278, 299 💬
183 XT-150 [1] XT-150---[1] 2 💬
184 Zilucoplan [1] Zilucoplan[2] Zilucoplan sodium ,
Zilucoplan 💬 		[1] C5 💬 [11] Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Regulation of actin cytoskeleton, Staphylococcus aureus infection, Systemic lupus erythematosus 💬[3] 2, 11, 62 💬
185 Zinc [1] Zinc---[7] 2, 56, 85, 171, 222, 223, 299 💬