Target Gene/Pathway Pathway / Gene
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Showing 1 to 10 of 47 entries
| No. | KEGG GENES | KEGG PATHWAY | KEGG DRUG | DrugBank | Disease ID | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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| 1 |
DHFR
💬1. DHFR
| [5] One carbon pool by folate One carbon pool by folate, Folate biosynthesis, Metabolic pathways, Biosynthesis of cofactors, Antifolate resistance [5] One carbon pool by folate, Folate biosynthesis, Metabolic pathways, Biosynthesis of cofactors, A ... | Methotrexate
Methotrexate
💬1. DHFR
| Methotrexate | [38] 11 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬 [38] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, ... 1. DHFR
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| 2 |
DHODH
💬2. DHODH
| [3] Pyrimidine metabolism Pyrimidine metabolism, Metabolic pathways, Biosynthesis of cofactors | Leflunomide
Leflunomide
💬2. DHODH
| Leflunomide | [12] 11 11, 40, 46, 49, 53, 66, 107, 162, 224, 270, 271, 300 💬2. DHODH
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| 3 |
DHFR2
💬3. DHFR2
| [5] One carbon pool by folate One carbon pool by folate, Folate biosynthesis, Metabolic pathways, Biosynthesis of cofactors, Antifolate resistance [5] One carbon pool by folate, Folate biosynthesis, Metabolic pathways, Biosynthesis of cofactors, A ... | Methotrexate
Methotrexate
💬3. DHFR2
| Methotrexate | [38] 11 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬 [38] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, ... 3. DHFR2
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| 4 |
FCER1A
💬4. FCER1A
| [4] Sphingolipid signaling pathway Sphingolipid signaling pathway, Phospholipase D signaling pathway, Fc epsilon RI signaling pathway, Asthma [4] Sphingolipid signaling pathway, Phospholipase D signaling pathway, Fc epsilon RI signaling pathw ... | Omalizumab
Omalizumab
💬4. FCER1A
| Omalizumab | [7] 46 46, 53, 65, 98, 162, 226, 299 💬
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| 5 |
FCGRT
💬5. FCGRT
| - | Efgartigimod alfa
Efgartigimod alfa
💬5. FCGRT
| Efgartigimod alfa | [6] 11 11, 14, 35, 53, 63, 162 💬
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| 6 |
ABL1
💬6. ABL1
| [11] ErbB signaling pathway ErbB signaling pathway, Ras signaling pathway, Cell cycle, Axon guidance, Neurotrophin signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, MicroRNAs in cancer, Chemical carcinogenesis - reactive oxygen species, Chronic myeloid leukemia, Viral myocarditis [11] ErbB signaling pathway, Ras signaling pathway, Cell cycle, Axon guidance, Neurotrophin signalin ... | Imatinib
Imatinib
💬6. ABL1
| Imatinib | [12] 13 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬6. ABL1
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| 7 |
NR3C1
💬7. NR3C1
| [1] Neuroactive ligand-receptor interaction Neuroactive ligand-receptor interaction | Dexamethasone
Dexamethasone
💬7. NR3C1
| Dexamethasone | [22] 13 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 81, 84, 96, 97, 162, 222, 235, 257, 283, 296, 299 💬 [22] 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 81, 84, 96, 97, 162, 222, 235, 257, 283, 296, 299💬 ... 7. NR3C1
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| 8 |
NR3C1
💬8. NR3C1
| [1] Neuroactive ligand-receptor interaction Neuroactive ligand-receptor interaction | Triamcinolone
Triamcinolone
💬8. NR3C1
| Triamcinolone | [11] 35 35, 46, 53, 56, 70, 90, 96, 107, 162, 226, 298 💬
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| 9 |
NR3C1
💬9. NR3C1
| [1] Neuroactive ligand-receptor interaction Neuroactive ligand-receptor interaction | Methylprednisolone
Methylprednisolone
💬9. NR3C1
| Methylprednisolone | [46] 2 2, 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 95, 96, 97, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296 💬 [46] 2, 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, ... 9. NR3C1
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| 10 |
NR3C1
💬10. NR3C1
| [1] Neuroactive ligand-receptor interaction Neuroactive ligand-receptor interaction | Prednisolone
Prednisolone
💬10. NR3C1
| Prednisolone | [42] 3 3, 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300 💬 [42] 3, 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, ... 10. NR3C1
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