Target Gene/Pathway Pathway / Gene

  

Search results

No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank Disease ID
1 CHRM3 💬 [11] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Cholinergic synapse, Taste transduction, Regulation of actin cytoskeleton, Insulin secretion, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Alzheimer disease, Pathways of neurodegeneration - multiple diseases Atropine 💬 Atropine [2] 2, 299 💬
2 CHRM3 💬 [11] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Cholinergic synapse, Taste transduction, Regulation of actin cytoskeleton, Insulin secretion, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Alzheimer disease, Pathways of neurodegeneration - multiple diseases Scopolamine 💬 Scopolamine [1] 2 💬
3 CHRM3 💬 [11] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Cholinergic synapse, Taste transduction, Regulation of actin cytoskeleton, Insulin secretion, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Alzheimer disease, Pathways of neurodegeneration - multiple diseases Chlorpromazine 💬 Chlorpromazine [1] 254 💬
4 CHRM3 💬 [11] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Cholinergic synapse, Taste transduction, Regulation of actin cytoskeleton, Insulin secretion, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Alzheimer disease, Pathways of neurodegeneration - multiple diseases Tropicamide 💬 Tropicamide [1] 6 💬
5 CHRM3 💬 [11] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Cholinergic synapse, Taste transduction, Regulation of actin cytoskeleton, Insulin secretion, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Alzheimer disease, Pathways of neurodegeneration - multiple diseases Oxybutynin 💬 Oxybutynin [3] 6, 13, 53 💬
6 CHRM3 💬 [11] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Cholinergic synapse, Taste transduction, Regulation of actin cytoskeleton, Insulin secretion, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Alzheimer disease, Pathways of neurodegeneration - multiple diseases Pilocarpine 💬 Pilocarpine [3] 6, 53, 299 💬
7 CHRM3 💬 [11] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Cholinergic synapse, Taste transduction, Regulation of actin cytoskeleton, Insulin secretion, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Alzheimer disease, Pathways of neurodegeneration - multiple diseases Tolterodine 💬 Tolterodine [2] 17, 53 💬
8 CHRM3 💬 [11] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Cholinergic synapse, Taste transduction, Regulation of actin cytoskeleton, Insulin secretion, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Alzheimer disease, Pathways of neurodegeneration - multiple diseases Darifenacin 💬 Darifenacin [2] 6, 13 💬
9 CHRM3 💬 [11] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Cholinergic synapse, Taste transduction, Regulation of actin cytoskeleton, Insulin secretion, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Alzheimer disease, Pathways of neurodegeneration - multiple diseases Fesoterodine 💬 Fesoterodine [1] 6 💬
10 CHRM3 💬 [11] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Cholinergic synapse, Taste transduction, Regulation of actin cytoskeleton, Insulin secretion, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Alzheimer disease, Pathways of neurodegeneration - multiple diseases Cevimeline 💬 Cevimeline [1] 53 💬
11 CHRM3 💬 [11] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Cholinergic synapse, Taste transduction, Regulation of actin cytoskeleton, Insulin secretion, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Alzheimer disease, Pathways of neurodegeneration - multiple diseases Propiverine 💬 Propiverine [1] 226 💬
12 CHRM3 💬 [11] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Cholinergic synapse, Taste transduction, Regulation of actin cytoskeleton, Insulin secretion, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Alzheimer disease, Pathways of neurodegeneration - multiple diseases Solifenacin 💬 Solifenacin [3] 6, 13, 53 💬
13 CHRM3 💬 [11] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Cholinergic synapse, Taste transduction, Regulation of actin cytoskeleton, Insulin secretion, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Alzheimer disease, Pathways of neurodegeneration - multiple diseases Trihexyphenidyl 💬 Trihexyphenidyl [2] 5, 6 💬
14 CHRM3 💬 [11] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Cholinergic synapse, Taste transduction, Regulation of actin cytoskeleton, Insulin secretion, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Alzheimer disease, Pathways of neurodegeneration - multiple diseases Blarcamesine 💬 Blarcamesine [1] 156 💬
15 HTR3C 💬 [2] Serotonergic synapse, Taste transduction Clozapine 💬 Clozapine [1] 6 💬
16 HTR3C 💬 [2] Serotonergic synapse, Taste transduction Ondansetron 💬 Ondansetron [3] 6, 97, 107 💬
17 HTR3C 💬 [2] Serotonergic synapse, Taste transduction Dolasetron 💬 Dolasetron [1] 46 💬
18 HTR3C 💬 [2] Serotonergic synapse, Taste transduction Vortioxetine 💬 Vortioxetine [1] 6 💬
19 HTR3D 💬 [2] Serotonergic synapse, Taste transduction Clozapine 💬 Clozapine [1] 6 💬
20 HTR3D 💬 [2] Serotonergic synapse, Taste transduction Ondansetron 💬 Ondansetron [3] 6, 97, 107 💬
21 HTR3D 💬 [2] Serotonergic synapse, Taste transduction Dolasetron 💬 Dolasetron [1] 46 💬
22 HTR3D 💬 [2] Serotonergic synapse, Taste transduction Vortioxetine 💬 Vortioxetine [1] 6 💬
23 GABBR1 💬 [7] cAMP signaling pathway, Neuroactive ligand-receptor interaction, GABAergic synapse, Taste transduction, Estrogen signaling pathway, GnRH secretion, Morphine addiction Baclofen 💬 Baclofen [8] 2, 10, 13, 18, 65, 70, 149, 206 💬
24 GABBR1 💬 [7] cAMP signaling pathway, Neuroactive ligand-receptor interaction, GABAergic synapse, Taste transduction, Estrogen signaling pathway, GnRH secretion, Morphine addiction Arbaclofen placarbil 💬 Arbaclofen Placarbil [1] 13 💬
25 GABBR1 💬 [7] cAMP signaling pathway, Neuroactive ligand-receptor interaction, GABAergic synapse, Taste transduction, Estrogen signaling pathway, GnRH secretion, Morphine addiction Arbaclofen 💬 Arbaclofen [2] 13, 206 💬
26 GABBR1 💬 [7] cAMP signaling pathway, Neuroactive ligand-receptor interaction, GABAergic synapse, Taste transduction, Estrogen signaling pathway, GnRH secretion, Morphine addiction Valiloxybate 💬 Valiloxybate [1] 6 💬
27 GABRA1 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Alprazolam 💬 Alprazolam [2] 8, 75 💬
28 GABRA1 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Clonazepam 💬 Clonazepam [1] 6 💬
29 GABRA1 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Diazepam 💬 Diazepam [3] 46, 155, 298 💬
30 GABRA1 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Lorazepam 💬 Lorazepam [1] 36 💬
31 GABRA1 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Topiramate 💬 Topiramate [6] 6, 97, 140, 144, 156, 193 💬
32 GABRA1 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Etomidate 💬 Etomidate [1] 6 💬
33 GABRA1 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Propofol 💬 Propofol [9] 6, 21, 22, 34, 46, 70, 75, 98, 296 💬
34 GABRA1 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Midazolam 💬 Midazolam [12] 2, 3, 6, 13, 21, 46, 70, 96, 97, 272, 298, 299 💬
35 GABRA1 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Flumazenil 💬 Flumazenil [5] 6, 13, 17, 18, 206 💬
36 GABRA1 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Clobazam 💬 Clobazam [2] 140, 144 💬
37 GABRA1 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Zopiclone 💬 Zopiclone [1] 6 💬
38 GABRA1 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Eszopiclone 💬 Eszopiclone [3] 6, 13, 46 💬
39 GABRA1 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Gaboxadol 💬 Gaboxadol [2] 201, 206 💬
40 GABRA1 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Ganaxolone 💬 Ganaxolone [4] 145, 152, 158, 206 💬
41 GABRA1 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Delorazepam 💬 Delorazepam [3] 6, 46, 97 💬
42 GABRA1 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Zolpidem 💬 Zolpidem [3] 5, 6, 46 💬
43 GABRA1 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Brexanolone 💬 Brexanolone [1] 205 💬
44 GABRA2 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Alprazolam 💬 Alprazolam [2] 8, 75 💬
45 GABRA2 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Clonazepam 💬 Clonazepam [1] 6 💬
46 GABRA2 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Diazepam 💬 Diazepam [3] 46, 155, 298 💬
47 GABRA2 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Lorazepam 💬 Lorazepam [1] 36 💬
48 GABRA2 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Topiramate 💬 Topiramate [6] 6, 97, 140, 144, 156, 193 💬
49 GABRA2 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Propofol 💬 Propofol [9] 6, 21, 22, 34, 46, 70, 75, 98, 296 💬
50 GABRA2 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Midazolam 💬 Midazolam [12] 2, 3, 6, 13, 21, 46, 70, 96, 97, 272, 298, 299 💬
51 GABRA2 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Flumazenil 💬 Flumazenil [5] 6, 13, 17, 18, 206 💬
52 GABRA2 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Clobazam 💬 Clobazam [2] 140, 144 💬
53 GABRA2 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Zopiclone 💬 Zopiclone [1] 6 💬
54 GABRA2 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Eszopiclone 💬 Eszopiclone [3] 6, 13, 46 💬
55 GABRA2 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Gaboxadol 💬 Gaboxadol [2] 201, 206 💬
56 GABRA2 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Ganaxolone 💬 Ganaxolone [4] 145, 152, 158, 206 💬
57 GABRA2 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Delorazepam 💬 Delorazepam [3] 6, 46, 97 💬
58 GABRA2 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Zolpidem 💬 Zolpidem [3] 5, 6, 46 💬
59 GABRA2 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Brexanolone 💬 Brexanolone [1] 205 💬
60 GABRA3 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Alprazolam 💬 Alprazolam [2] 8, 75 💬
61 GABRA3 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Clonazepam 💬 Clonazepam [1] 6 💬
62 GABRA3 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Diazepam 💬 Diazepam [3] 46, 155, 298 💬
63 GABRA3 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Lorazepam 💬 Lorazepam [1] 36 💬
64 GABRA3 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Topiramate 💬 Topiramate [6] 6, 97, 140, 144, 156, 193 💬
65 GABRA3 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Propofol 💬 Propofol [9] 6, 21, 22, 34, 46, 70, 75, 98, 296 💬
66 GABRA3 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Midazolam 💬 Midazolam [12] 2, 3, 6, 13, 21, 46, 70, 96, 97, 272, 298, 299 💬
67 GABRA3 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Flumazenil 💬 Flumazenil [5] 6, 13, 17, 18, 206 💬
68 GABRA3 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Clobazam 💬 Clobazam [2] 140, 144 💬
69 GABRA3 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Zopiclone 💬 Zopiclone [1] 6 💬
70 GABRA3 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Eszopiclone 💬 Eszopiclone [3] 6, 13, 46 💬
71 GABRA3 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Gaboxadol 💬 Gaboxadol [2] 201, 206 💬
72 GABRA3 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Ganaxolone 💬 Ganaxolone [4] 145, 152, 158, 206 💬
73 GABRA3 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Delorazepam 💬 Delorazepam [3] 6, 46, 97 💬
74 GABRA3 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Zolpidem 💬 Zolpidem [3] 5, 6, 46 💬
75 GABRA3 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Brexanolone 💬 Brexanolone [1] 205 💬
76 GABRA4 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Alprazolam 💬 Alprazolam [2] 8, 75 💬
77 GABRA4 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Clonazepam 💬 Clonazepam [1] 6 💬
78 GABRA4 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Diazepam 💬 Diazepam [3] 46, 155, 298 💬
79 GABRA4 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Lorazepam 💬 Lorazepam [1] 36 💬
80 GABRA4 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Topiramate 💬 Topiramate [6] 6, 97, 140, 144, 156, 193 💬
81 GABRA4 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Propofol 💬 Propofol [9] 6, 21, 22, 34, 46, 70, 75, 98, 296 💬
82 GABRA4 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Midazolam 💬 Midazolam [12] 2, 3, 6, 13, 21, 46, 70, 96, 97, 272, 298, 299 💬
83 GABRA4 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Flumazenil 💬 Flumazenil [5] 6, 13, 17, 18, 206 💬
84 GABRA4 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Clobazam 💬 Clobazam [2] 140, 144 💬
85 GABRA4 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Zopiclone 💬 Zopiclone [1] 6 💬
86 GABRA4 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Eszopiclone 💬 Eszopiclone [3] 6, 13, 46 💬
87 GABRA4 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Gaboxadol 💬 Gaboxadol [2] 201, 206 💬
88 GABRA4 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Ganaxolone 💬 Ganaxolone [4] 145, 152, 158, 206 💬
89 GABRA4 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Delorazepam 💬 Delorazepam [3] 6, 46, 97 💬
90 GABRA4 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Zolpidem 💬 Zolpidem [3] 5, 6, 46 💬
91 GABRA4 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Brexanolone 💬 Brexanolone [1] 205 💬
92 GABRA5 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Alprazolam 💬 Alprazolam [2] 8, 75 💬
93 GABRA5 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Clonazepam 💬 Clonazepam [1] 6 💬
94 GABRA5 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Diazepam 💬 Diazepam [3] 46, 155, 298 💬
95 GABRA5 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Lorazepam 💬 Lorazepam [1] 36 💬
96 GABRA5 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Topiramate 💬 Topiramate [6] 6, 97, 140, 144, 156, 193 💬
97 GABRA5 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Propofol 💬 Propofol [9] 6, 21, 22, 34, 46, 70, 75, 98, 296 💬
98 GABRA5 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Midazolam 💬 Midazolam [12] 2, 3, 6, 13, 21, 46, 70, 96, 97, 272, 298, 299 💬
99 GABRA5 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Flumazenil 💬 Flumazenil [5] 6, 13, 17, 18, 206 💬
100 GABRA5 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Clobazam 💬 Clobazam [2] 140, 144 💬
101 GABRA5 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Zopiclone 💬 Zopiclone [1] 6 💬
102 GABRA5 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Eszopiclone 💬 Eszopiclone [3] 6, 13, 46 💬
103 GABRA5 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Gaboxadol 💬 Gaboxadol [2] 201, 206 💬
104 GABRA5 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Ganaxolone 💬 Ganaxolone [4] 145, 152, 158, 206 💬
105 GABRA5 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Delorazepam 💬 Delorazepam [3] 6, 46, 97 💬
106 GABRA5 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Zolpidem 💬 Zolpidem [3] 5, 6, 46 💬
107 GABRA5 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Brexanolone 💬 Brexanolone [1] 205 💬
108 GABRA6 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Alprazolam 💬 Alprazolam [2] 8, 75 💬
109 GABRA6 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Clonazepam 💬 Clonazepam [1] 6 💬
110 GABRA6 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Diazepam 💬 Diazepam [3] 46, 155, 298 💬
111 GABRA6 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Lorazepam 💬 Lorazepam [1] 36 💬
112 GABRA6 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Topiramate 💬 Topiramate [6] 6, 97, 140, 144, 156, 193 💬
113 GABRA6 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Propofol 💬 Propofol [9] 6, 21, 22, 34, 46, 70, 75, 98, 296 💬
114 GABRA6 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Midazolam 💬 Midazolam [12] 2, 3, 6, 13, 21, 46, 70, 96, 97, 272, 298, 299 💬
115 GABRA6 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Flumazenil 💬 Flumazenil [5] 6, 13, 17, 18, 206 💬
116 GABRA6 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Clobazam 💬 Clobazam [2] 140, 144 💬
117 GABRA6 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Zopiclone 💬 Zopiclone [1] 6 💬
118 GABRA6 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Eszopiclone 💬 Eszopiclone [3] 6, 13, 46 💬
119 GABRA6 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Gaboxadol 💬 Gaboxadol [2] 201, 206 💬
120 GABRA6 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Ganaxolone 💬 Ganaxolone [4] 145, 152, 158, 206 💬
121 GABRA6 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Delorazepam 💬 Delorazepam [3] 6, 46, 97 💬
122 GABRA6 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Zolpidem 💬 Zolpidem [3] 5, 6, 46 💬
123 GABRA6 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Brexanolone 💬 Brexanolone [1] 205 💬
124 HTR3E 💬 [2] Serotonergic synapse, Taste transduction Clozapine 💬 Clozapine [1] 6 💬
125 HTR3E 💬 [2] Serotonergic synapse, Taste transduction Ondansetron 💬 Ondansetron [3] 6, 97, 107 💬
126 HTR3E 💬 [2] Serotonergic synapse, Taste transduction Dolasetron 💬 Dolasetron [1] 46 💬
127 HTR3E 💬 [2] Serotonergic synapse, Taste transduction Vortioxetine 💬 Vortioxetine [1] 6 💬
128 HTR1A 💬 [4] cAMP signaling pathway, Neuroactive ligand-receptor interaction, Serotonergic synapse, Taste transduction Aripiprazole 💬 Aripiprazole [2] 6, 206 💬
129 HTR1A 💬 [4] cAMP signaling pathway, Neuroactive ligand-receptor interaction, Serotonergic synapse, Taste transduction Buspirone 💬 Buspirone [2] 6, 51 💬
130 HTR1A 💬 [4] cAMP signaling pathway, Neuroactive ligand-receptor interaction, Serotonergic synapse, Taste transduction Pardoprunox 💬 Pardoprunox [1] 6 💬
131 HTR1A 💬 [4] cAMP signaling pathway, Neuroactive ligand-receptor interaction, Serotonergic synapse, Taste transduction Cariprazine 💬 Cariprazine [1] 21 💬
132 HTR1A 💬 [4] cAMP signaling pathway, Neuroactive ligand-receptor interaction, Serotonergic synapse, Taste transduction Vortioxetine 💬 Vortioxetine [1] 6 💬
133 HTR1B 💬 [4] cAMP signaling pathway, Neuroactive ligand-receptor interaction, Serotonergic synapse, Taste transduction Zolmitriptan 💬 Zolmitriptan [1] 6 💬
134 HTR1D 💬 [4] cAMP signaling pathway, Neuroactive ligand-receptor interaction, Serotonergic synapse, Taste transduction Zolmitriptan 💬 Zolmitriptan [1] 6 💬
135 HTR1D 💬 [4] cAMP signaling pathway, Neuroactive ligand-receptor interaction, Serotonergic synapse, Taste transduction Fenfluramine 💬 Fenfluramine [4] 140, 144, 145, 149 💬
136 HTR3A 💬 [2] Serotonergic synapse, Taste transduction Cisapride 💬 Cisapride [1] 13 💬
137 HTR3A 💬 [2] Serotonergic synapse, Taste transduction Clozapine 💬 Clozapine [1] 6 💬
138 HTR3A 💬 [2] Serotonergic synapse, Taste transduction Ondansetron 💬 Ondansetron [3] 6, 97, 107 💬
139 HTR3A 💬 [2] Serotonergic synapse, Taste transduction Cisapride 💬 Cisapride [1] 13 💬
140 HTR3A 💬 [2] Serotonergic synapse, Taste transduction Dolasetron 💬 Dolasetron [1] 46 💬
141 HTR3A 💬 [2] Serotonergic synapse, Taste transduction Vortioxetine 💬 Vortioxetine [1] 6 💬
142 P2RX3 💬 [3] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Taste transduction Gefapixant 💬 Gefapixant [2] 85, 226 💬
143 PDE1A 💬 [7] Purine metabolism, Metabolic pathways, Calcium signaling pathway, Olfactory transduction, Taste transduction, Renin secretion, Morphine addiction Aminophylline 💬 Aminophylline [1] 63 💬
144 PDE1A 💬 [7] Purine metabolism, Metabolic pathways, Calcium signaling pathway, Olfactory transduction, Taste transduction, Renin secretion, Morphine addiction Theophylline 💬 Theophylline [2] 236, 299 💬
145 PDE1A 💬 [7] Purine metabolism, Metabolic pathways, Calcium signaling pathway, Olfactory transduction, Taste transduction, Renin secretion, Morphine addiction Theophylline 💬 Theophylline [2] 236, 299 💬
146 PDE1A 💬 [7] Purine metabolism, Metabolic pathways, Calcium signaling pathway, Olfactory transduction, Taste transduction, Renin secretion, Morphine addiction Bucladesine 💬 Bucladesine [1] 246 💬
147 PDE1A 💬 [7] Purine metabolism, Metabolic pathways, Calcium signaling pathway, Olfactory transduction, Taste transduction, Renin secretion, Morphine addiction Flavoxate 💬 Flavoxate [1] 226 💬
148 PDE1C 💬 [7] Purine metabolism, Metabolic pathways, Calcium signaling pathway, Olfactory transduction, Taste transduction, Renin secretion, Morphine addiction Aminophylline 💬 Aminophylline [1] 63 💬
149 PDE1C 💬 [7] Purine metabolism, Metabolic pathways, Calcium signaling pathway, Olfactory transduction, Taste transduction, Renin secretion, Morphine addiction Theophylline 💬 Theophylline [2] 236, 299 💬
150 PDE1C 💬 [7] Purine metabolism, Metabolic pathways, Calcium signaling pathway, Olfactory transduction, Taste transduction, Renin secretion, Morphine addiction Theophylline 💬 Theophylline [2] 236, 299 💬
151 PDE1C 💬 [7] Purine metabolism, Metabolic pathways, Calcium signaling pathway, Olfactory transduction, Taste transduction, Renin secretion, Morphine addiction Bucladesine 💬 Bucladesine [1] 246 💬
152 PDE1C 💬 [7] Purine metabolism, Metabolic pathways, Calcium signaling pathway, Olfactory transduction, Taste transduction, Renin secretion, Morphine addiction Flavoxate 💬 Flavoxate [1] 226 💬
153 PDE1B 💬 [7] Purine metabolism, Metabolic pathways, Calcium signaling pathway, Olfactory transduction, Taste transduction, Renin secretion, Morphine addiction Aminophylline 💬 Aminophylline [1] 63 💬
154 PDE1B 💬 [7] Purine metabolism, Metabolic pathways, Calcium signaling pathway, Olfactory transduction, Taste transduction, Renin secretion, Morphine addiction Theophylline 💬 Theophylline [2] 236, 299 💬
155 PDE1B 💬 [7] Purine metabolism, Metabolic pathways, Calcium signaling pathway, Olfactory transduction, Taste transduction, Renin secretion, Morphine addiction Caffeine 💬 Caffeine [8] 2, 6, 21, 46, 78, 96, 97, 265 💬
156 PDE1B 💬 [7] Purine metabolism, Metabolic pathways, Calcium signaling pathway, Olfactory transduction, Taste transduction, Renin secretion, Morphine addiction Caffeine hydrate 💬 Caffeine [8] 2, 6, 21, 46, 78, 96, 97, 265 💬
157 PDE1B 💬 [7] Purine metabolism, Metabolic pathways, Calcium signaling pathway, Olfactory transduction, Taste transduction, Renin secretion, Morphine addiction Theophylline 💬 Theophylline [2] 236, 299 💬
158 PDE1B 💬 [7] Purine metabolism, Metabolic pathways, Calcium signaling pathway, Olfactory transduction, Taste transduction, Renin secretion, Morphine addiction Bucladesine 💬 Bucladesine [1] 246 💬
159 PDE1B 💬 [7] Purine metabolism, Metabolic pathways, Calcium signaling pathway, Olfactory transduction, Taste transduction, Renin secretion, Morphine addiction Flavoxate 💬 Flavoxate [1] 226 💬
160 SCN2A 💬 [1] Taste transduction Carbamazepine 💬 Carbamazepine [3] 6, 13, 231 💬
161 SCN2A 💬 [1] Taste transduction Lamotrigine 💬 Lamotrigine [5] 13, 34, 38, 114, 144 💬
162 SCN2A 💬 [1] Taste transduction Lidocaine 💬 Lidocaine [13] 6, 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256 💬
163 SCN2A 💬 [1] Taste transduction Phenytoin 💬 Phenytoin [1] 13 💬
164 SCN2A 💬 [1] Taste transduction Oxcarbazepine 💬 Oxcarbazepine [1] 13 💬
165 SCN2A 💬 [1] Taste transduction Topiramate 💬 Topiramate [6] 6, 97, 140, 144, 156, 193 💬
166 SCN2A 💬 [1] Taste transduction Zonisamide 💬 Zonisamide [1] 6 💬
167 SCN2A 💬 [1] Taste transduction Amiodarone 💬 Amiodarone [2] 28, 127 💬
168 SCN2A 💬 [1] Taste transduction Cifenline 💬 Cibenzoline [1] 58 💬
169 SCN2A 💬 [1] Taste transduction Rufinamide 💬 Rufinamide [1] 144 💬
170 SCN2A 💬 [1] Taste transduction Bupivacaine 💬 Bupivacaine [8] 46, 51, 53, 70, 96, 168, 226, 298 💬
171 SCN2A 💬 [1] Taste transduction Flecainide 💬 Flecainide [1] 6 💬
172 SCN2A 💬 [1] Taste transduction Levobupivacaine 💬 Levobupivacaine [1] 46 💬
173 SCN2A 💬 [1] Taste transduction Lidocaine hydrochloride monohydrate 💬 Lidocaine [13] 6, 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256 💬
174 SCN2A 💬 [1] Taste transduction Mexiletine 💬 Mexiletine [5] 1, 2, 10, 113, 114 💬
175 SCN2A 💬 [1] Taste transduction Oxybuprocaine 💬 Oxybuprocaine [1] 6 💬
176 SCN2A 💬 [1] Taste transduction Quinidine 💬 Quinidine [3] 2, 8, 13 💬
177 SCN2A 💬 [1] Taste transduction Ropivacaine 💬 Ropivacaine [4] 22, 36, 46, 70 💬
178 SCN2A 💬 [1] Taste transduction Eleclazine 💬 Eleclazine [1] 58 💬
179 SCN3A 💬 [1] Taste transduction Carbamazepine 💬 Carbamazepine [3] 6, 13, 231 💬
180 SCN3A 💬 [1] Taste transduction Lamotrigine 💬 Lamotrigine [5] 13, 34, 38, 114, 144 💬
181 SCN3A 💬 [1] Taste transduction Lidocaine 💬 Lidocaine [13] 6, 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256 💬
182 SCN3A 💬 [1] Taste transduction Phenytoin 💬 Phenytoin [1] 13 💬
183 SCN3A 💬 [1] Taste transduction Oxcarbazepine 💬 Oxcarbazepine [1] 13 💬
184 SCN3A 💬 [1] Taste transduction Topiramate 💬 Topiramate [6] 6, 97, 140, 144, 156, 193 💬
185 SCN3A 💬 [1] Taste transduction Zonisamide 💬 Zonisamide [1] 6 💬
186 SCN3A 💬 [1] Taste transduction Amiodarone 💬 Amiodarone [2] 28, 127 💬
187 SCN3A 💬 [1] Taste transduction Cifenline 💬 Cibenzoline [1] 58 💬
188 SCN3A 💬 [1] Taste transduction Rufinamide 💬 Rufinamide [1] 144 💬
189 SCN3A 💬 [1] Taste transduction Lacosamide 💬 Lacosamide [4] 2, 46, 149, 298 💬
190 SCN3A 💬 [1] Taste transduction Bupivacaine 💬 Bupivacaine [8] 46, 51, 53, 70, 96, 168, 226, 298 💬
191 SCN3A 💬 [1] Taste transduction Flecainide 💬 Flecainide [1] 6 💬
192 SCN3A 💬 [1] Taste transduction Levobupivacaine 💬 Levobupivacaine [1] 46 💬
193 SCN3A 💬 [1] Taste transduction Lidocaine hydrochloride monohydrate 💬 Lidocaine [13] 6, 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256 💬
194 SCN3A 💬 [1] Taste transduction Mexiletine 💬 Mexiletine [5] 1, 2, 10, 113, 114 💬
195 SCN3A 💬 [1] Taste transduction Oxybuprocaine 💬 Oxybuprocaine [1] 6 💬
196 SCN3A 💬 [1] Taste transduction Quinidine 💬 Quinidine [3] 2, 8, 13 💬
197 SCN3A 💬 [1] Taste transduction Ropivacaine 💬 Ropivacaine [4] 22, 36, 46, 70 💬
198 SCN3A 💬 [1] Taste transduction Eleclazine 💬 Eleclazine [1] 58 💬
199 SCN9A 💬 [1] Taste transduction Carbamazepine 💬 Carbamazepine [3] 6, 13, 231 💬
200 SCN9A 💬 [1] Taste transduction Lamotrigine 💬 Lamotrigine [5] 13, 34, 38, 114, 144 💬
201 SCN9A 💬 [1] Taste transduction Lidocaine 💬 Lidocaine [13] 6, 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256 💬
202 SCN9A 💬 [1] Taste transduction Phenytoin 💬 Phenytoin [1] 13 💬
203 SCN9A 💬 [1] Taste transduction Oxcarbazepine 💬 Oxcarbazepine [1] 13 💬
204 SCN9A 💬 [1] Taste transduction Topiramate 💬 Topiramate [6] 6, 97, 140, 144, 156, 193 💬
205 SCN9A 💬 [1] Taste transduction Zonisamide 💬 Zonisamide [1] 6 💬
206 SCN9A 💬 [1] Taste transduction Amiodarone 💬 Amiodarone [2] 28, 127 💬
207 SCN9A 💬 [1] Taste transduction Cifenline 💬 Cibenzoline [1] 58 💬
208 SCN9A 💬 [1] Taste transduction Rufinamide 💬 Rufinamide [1] 144 💬
209 SCN9A 💬 [1] Taste transduction Lacosamide 💬 Lacosamide [4] 2, 46, 149, 298 💬
210 SCN9A 💬 [1] Taste transduction Bupivacaine 💬 Bupivacaine [8] 46, 51, 53, 70, 96, 168, 226, 298 💬
211 SCN9A 💬 [1] Taste transduction Flecainide 💬 Flecainide [1] 6 💬
212 SCN9A 💬 [1] Taste transduction Levobupivacaine 💬 Levobupivacaine [1] 46 💬
213 SCN9A 💬 [1] Taste transduction Lidocaine hydrochloride monohydrate 💬 Lidocaine [13] 6, 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256 💬
214 SCN9A 💬 [1] Taste transduction Mexiletine 💬 Mexiletine [5] 1, 2, 10, 113, 114 💬
215 SCN9A 💬 [1] Taste transduction Oxybuprocaine 💬 Oxybuprocaine [1] 6 💬
216 SCN9A 💬 [1] Taste transduction Quinidine 💬 Quinidine [3] 2, 8, 13 💬
217 SCN9A 💬 [1] Taste transduction Ropivacaine 💬 Ropivacaine [4] 22, 36, 46, 70 💬
218 SCN9A 💬 [1] Taste transduction Eleclazine 💬 Eleclazine [1] 58 💬
219 SCNN1A 💬 [2] Taste transduction, Aldosterone-regulated sodium reabsorption Amiloride 💬 Amiloride [4] 13, 67, 225, 299 💬
220 SCNN1B 💬 [2] Taste transduction, Aldosterone-regulated sodium reabsorption Amiloride 💬 Amiloride [4] 13, 67, 225, 299 💬
221 SCNN1G 💬 [2] Taste transduction, Aldosterone-regulated sodium reabsorption Amiloride 💬 Amiloride [4] 13, 67, 225, 299 💬
222 CACNA1C 💬 [34] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Circadian entrainment, Long-term potentiation, Retrograde endocannabinoid signaling, Glutamatergic synapse, Cholinergic synapse, Serotonergic synapse, GABAergic synapse, Dopaminergic synapse, Taste transduction, Insulin secretion, GnRH signaling pathway, Oxytocin signaling pathway, Renin secretion, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Type II diabetes mellitus, Cushing syndrome, Growth hormone synthesis, secretion and action, Alzheimer disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Chemical carcinogenesis - receptor activation, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Isradipine 💬 Isradipine [1] 6 💬
223 CACNA1C 💬 [34] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Circadian entrainment, Long-term potentiation, Retrograde endocannabinoid signaling, Glutamatergic synapse, Cholinergic synapse, Serotonergic synapse, GABAergic synapse, Dopaminergic synapse, Taste transduction, Insulin secretion, GnRH signaling pathway, Oxytocin signaling pathway, Renin secretion, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Type II diabetes mellitus, Cushing syndrome, Growth hormone synthesis, secretion and action, Alzheimer disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Chemical carcinogenesis - receptor activation, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Nifedipine 💬 Nifedipine [2] 50, 81 💬
224 CACNA1C 💬 [34] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Circadian entrainment, Long-term potentiation, Retrograde endocannabinoid signaling, Glutamatergic synapse, Cholinergic synapse, Serotonergic synapse, GABAergic synapse, Dopaminergic synapse, Taste transduction, Insulin secretion, GnRH signaling pathway, Oxytocin signaling pathway, Renin secretion, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Type II diabetes mellitus, Cushing syndrome, Growth hormone synthesis, secretion and action, Alzheimer disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Chemical carcinogenesis - receptor activation, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Topiramate 💬 Topiramate [6] 6, 97, 140, 144, 156, 193 💬
225 CACNA1C 💬 [34] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Circadian entrainment, Long-term potentiation, Retrograde endocannabinoid signaling, Glutamatergic synapse, Cholinergic synapse, Serotonergic synapse, GABAergic synapse, Dopaminergic synapse, Taste transduction, Insulin secretion, GnRH signaling pathway, Oxytocin signaling pathway, Renin secretion, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Type II diabetes mellitus, Cushing syndrome, Growth hormone synthesis, secretion and action, Alzheimer disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Chemical carcinogenesis - receptor activation, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Cilnidipine 💬 Cilnidipine [1] 67 💬
226 CACNA1C 💬 [34] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Circadian entrainment, Long-term potentiation, Retrograde endocannabinoid signaling, Glutamatergic synapse, Cholinergic synapse, Serotonergic synapse, GABAergic synapse, Dopaminergic synapse, Taste transduction, Insulin secretion, GnRH signaling pathway, Oxytocin signaling pathway, Renin secretion, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Type II diabetes mellitus, Cushing syndrome, Growth hormone synthesis, secretion and action, Alzheimer disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Chemical carcinogenesis - receptor activation, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Nilvadipine 💬 Nilvadipine [1] 90 💬
227 CACNA1C 💬 [34] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Circadian entrainment, Long-term potentiation, Retrograde endocannabinoid signaling, Glutamatergic synapse, Cholinergic synapse, Serotonergic synapse, GABAergic synapse, Dopaminergic synapse, Taste transduction, Insulin secretion, GnRH signaling pathway, Oxytocin signaling pathway, Renin secretion, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Type II diabetes mellitus, Cushing syndrome, Growth hormone synthesis, secretion and action, Alzheimer disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Chemical carcinogenesis - receptor activation, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Verapamil 💬 Verapamil [4] 58, 96, 140, 167 💬
228 CACNA1C 💬 [34] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Circadian entrainment, Long-term potentiation, Retrograde endocannabinoid signaling, Glutamatergic synapse, Cholinergic synapse, Serotonergic synapse, GABAergic synapse, Dopaminergic synapse, Taste transduction, Insulin secretion, GnRH signaling pathway, Oxytocin signaling pathway, Renin secretion, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Type II diabetes mellitus, Cushing syndrome, Growth hormone synthesis, secretion and action, Alzheimer disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Chemical carcinogenesis - receptor activation, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Amlodipine 💬 Amlodipine [4] 13, 51, 67, 298 💬
229 CACNA1C 💬 [34] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Circadian entrainment, Long-term potentiation, Retrograde endocannabinoid signaling, Glutamatergic synapse, Cholinergic synapse, Serotonergic synapse, GABAergic synapse, Dopaminergic synapse, Taste transduction, Insulin secretion, GnRH signaling pathway, Oxytocin signaling pathway, Renin secretion, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Type II diabetes mellitus, Cushing syndrome, Growth hormone synthesis, secretion and action, Alzheimer disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Chemical carcinogenesis - receptor activation, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Diltiazem 💬 Diltiazem [3] 51, 58, 86 💬
230 CACNA1C 💬 [34] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Circadian entrainment, Long-term potentiation, Retrograde endocannabinoid signaling, Glutamatergic synapse, Cholinergic synapse, Serotonergic synapse, GABAergic synapse, Dopaminergic synapse, Taste transduction, Insulin secretion, GnRH signaling pathway, Oxytocin signaling pathway, Renin secretion, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Type II diabetes mellitus, Cushing syndrome, Growth hormone synthesis, secretion and action, Alzheimer disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Chemical carcinogenesis - receptor activation, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Nicardipine 💬 Nicardipine [2] 70, 86 💬
231 CACNA1C 💬 [34] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Circadian entrainment, Long-term potentiation, Retrograde endocannabinoid signaling, Glutamatergic synapse, Cholinergic synapse, Serotonergic synapse, GABAergic synapse, Dopaminergic synapse, Taste transduction, Insulin secretion, GnRH signaling pathway, Oxytocin signaling pathway, Renin secretion, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Type II diabetes mellitus, Cushing syndrome, Growth hormone synthesis, secretion and action, Alzheimer disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Chemical carcinogenesis - receptor activation, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Perhexiline 💬 Perhexiline [2] 58, 272 💬
232 CACNA1C 💬 [34] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Circadian entrainment, Long-term potentiation, Retrograde endocannabinoid signaling, Glutamatergic synapse, Cholinergic synapse, Serotonergic synapse, GABAergic synapse, Dopaminergic synapse, Taste transduction, Insulin secretion, GnRH signaling pathway, Oxytocin signaling pathway, Renin secretion, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Type II diabetes mellitus, Cushing syndrome, Growth hormone synthesis, secretion and action, Alzheimer disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Chemical carcinogenesis - receptor activation, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Propiverine 💬 Propiverine [1] 226 💬
233 TAS1R2 💬 [2] Taste transduction, Carbohydrate digestion and absorption Aspartame 💬 Aspartame [4] 6, 13, 67, 86 💬
234 TAS1R3 💬 [2] Taste transduction, Carbohydrate digestion and absorption Aspartame 💬 Aspartame [4] 6, 13, 67, 86 💬
235 HTR3B 💬 [2] Serotonergic synapse, Taste transduction Clozapine 💬 Clozapine [1] 6 💬
236 HTR3B 💬 [2] Serotonergic synapse, Taste transduction Ondansetron 💬 Ondansetron [3] 6, 97, 107 💬
237 HTR3B 💬 [2] Serotonergic synapse, Taste transduction Dolasetron 💬 Dolasetron [1] 46 💬
238 HTR3B 💬 [2] Serotonergic synapse, Taste transduction Vortioxetine 💬 Vortioxetine [1] 6 💬
239 GABBR2 💬 [7] cAMP signaling pathway, Neuroactive ligand-receptor interaction, GABAergic synapse, Taste transduction, Estrogen signaling pathway, GnRH secretion, Morphine addiction Baclofen 💬 Baclofen [8] 2, 10, 13, 18, 65, 70, 149, 206 💬
240 GABBR2 💬 [7] cAMP signaling pathway, Neuroactive ligand-receptor interaction, GABAergic synapse, Taste transduction, Estrogen signaling pathway, GnRH secretion, Morphine addiction Arbaclofen placarbil 💬 Arbaclofen Placarbil [1] 13 💬
241 GABBR2 💬 [7] cAMP signaling pathway, Neuroactive ligand-receptor interaction, GABAergic synapse, Taste transduction, Estrogen signaling pathway, GnRH secretion, Morphine addiction Arbaclofen 💬 Arbaclofen [2] 13, 206 💬
242 GABBR2 💬 [7] cAMP signaling pathway, Neuroactive ligand-receptor interaction, GABAergic synapse, Taste transduction, Estrogen signaling pathway, GnRH secretion, Morphine addiction Valiloxybate 💬 Valiloxybate [1] 6 💬