Target Gene/Pathway Pathway / Gene


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No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank 指定難病告示番号
1 ABAT 💬 6件: Alanine, aspartate and glutamate metabolism, Valine, leucine and isoleucine degradation, beta-Alanine metabolism, Propanoate metabolism, Butanoate metabolism, GABAergic synapse Vigabatrin 💬 Vigabatrin 2件: 145, 158 💬
2 CNR1 💬 4件: Rap1 signaling pathway, Neuroactive ligand-receptor interaction, Thermogenesis, Retrograde endocannabinoid signaling Cannabidiol 💬 Cannabidiol 20件: 6, 8, 13, 19, 36, 46, 51, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271 💬
3 CNR2 💬 1件: Neuroactive ligand-receptor interaction Cannabidiol 💬 Cannabidiol 20件: 6, 8, 13, 19, 36, 46, 51, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271 💬
4 GABRA 💬 7件: Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Ganaxolone 💬 Ganaxolone 4件: 145, 152, 158, 206 💬
5 GABRA 💬 7件: Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Ganaxolone 💬 Ganaxolone 4件: 145, 152, 158, 206 💬
6 GABRA 💬 7件: Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Ganaxolone 💬 Ganaxolone 4件: 145, 152, 158, 206 💬
7 GABRA 💬 7件: Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Ganaxolone 💬 Ganaxolone 4件: 145, 152, 158, 206 💬
8 GABRA 💬 7件: Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Ganaxolone 💬 Ganaxolone 4件: 145, 152, 158, 206 💬
9 GABRA 💬 7件: Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Ganaxolone 💬 Ganaxolone 4件: 145, 152, 158, 206 💬
10 GABRB 💬 7件: Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Retrograde endocannabinoid signaling, Serotonergic synapse, GABAergic synapse, Morphine addiction, Nicotine addiction Ganaxolone 💬 Ganaxolone 4件: 145, 152, 158, 206 💬
11 GABRB 💬 7件: Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Retrograde endocannabinoid signaling, Serotonergic synapse, GABAergic synapse, Morphine addiction, Nicotine addiction Ganaxolone 💬 Ganaxolone 4件: 145, 152, 158, 206 💬
12 GABRB 💬 7件: Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Retrograde endocannabinoid signaling, Serotonergic synapse, GABAergic synapse, Morphine addiction, Nicotine addiction Ganaxolone 💬 Ganaxolone 4件: 145, 152, 158, 206 💬
13 GABRD 💬 6件: Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Ganaxolone 💬 Ganaxolone 4件: 145, 152, 158, 206 💬
14 GABRE 💬 6件: Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Ganaxolone 💬 Ganaxolone 4件: 145, 152, 158, 206 💬
15 GABRG 💬 6件: Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Ganaxolone 💬 Ganaxolone 4件: 145, 152, 158, 206 💬
16 GABRG 💬 6件: Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Ganaxolone 💬 Ganaxolone 4件: 145, 152, 158, 206 💬
17 GABRG 💬 6件: Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Ganaxolone 💬 Ganaxolone 4件: 145, 152, 158, 206 💬
18 GABRP 💬 6件: Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Ganaxolone 💬 Ganaxolone 4件: 145, 152, 158, 206 💬
19 GABRQ 💬 6件: Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Ganaxolone 💬 Ganaxolone 4件: 145, 152, 158, 206 💬
20 HRH2 💬 4件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Gastric acid secretion Famotidine 💬 Famotidine 7件: 6, 46, 61, 86, 98, 145, 300 💬
21 HTR1 💬 5件: cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Serotonergic synapse, Taste transduction Fenfluramine 💬 Fenfluramine 4件: 140, 144, 145, 149 💬
22 HTR1 💬 5件: cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Serotonergic synapse, Taste transduction Fenfluramine hydrochloride 💬 Fenfluramine 4件: 140, 144, 145, 149 💬
23 HTR2 💬 6件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Gap junction, Serotonergic synapse, Inflammatory mediator regulation of TRP channels Fenfluramine hydrochloride 💬 Fenfluramine 4件: 140, 144, 145, 149 💬
24 HTR2 💬 6件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Gap junction, Serotonergic synapse, Inflammatory mediator regulation of TRP channels Fenfluramine hydrochloride 💬 Fenfluramine 4件: 140, 144, 145, 149 💬
25 HTR2 💬 6件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Gap junction, Serotonergic synapse, Inflammatory mediator regulation of TRP channels Fenfluramine 💬 Fenfluramine 4件: 140, 144, 145, 149 💬
26 HTR2 💬 6件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Gap junction, Serotonergic synapse, Inflammatory mediator regulation of TRP channels Fenfluramine 💬 Fenfluramine 4件: 140, 144, 145, 149 💬
27 MC2R 💬 6件: cAMP signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome Corticotropin, repository 💬 Corticotropin 11件: 13, 46, 50, 66, 75, 78, 81, 84, 145, 205, 222 💬
28 MC2R 💬 6件: cAMP signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome Tetracosactide acetate 💬 Tetracosactide 5件: 78, 83, 113, 145, 222 💬
29 MC2R 💬 6件: cAMP signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome Corticotropin 💬 Corticotropin 11件: 13, 46, 50, 66, 75, 78, 81, 84, 145, 205, 222 💬
30 MC2R 💬 6件: cAMP signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome Cosyntropin 💬 Tetracosactide 5件: 78, 83, 113, 145, 222 💬
31 MTNR1A 💬 2件: Neuroactive ligand-receptor interaction, Circadian entrainment Melatonin 💬 Melatonin 17件: 2, 6, 8, 13, 37, 46, 49, 72, 78, 86, 90, 96, 97, 145, 149, 202, 265 💬
32 MTNR1B 💬 2件: Neuroactive ligand-receptor interaction, Circadian entrainment Melatonin 💬 Melatonin 17件: 2, 6, 8, 13, 37, 46, 49, 72, 78, 86, 90, 96, 97, 145, 149, 202, 265 💬
33 NR3C1 💬 1件: Neuroactive ligand-receptor interaction Prednisolone 💬 Prednisolone 41件: 3, 11, 13, 14, 18, 25, 26, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 54, 56, 60, 61, 63, 64, 66, 81, 84, 85, 95, 96, 97, 113, 145, 162, 222, 251, 269, 271, 296, 299, 300 💬
34 NR3C1 💬 1件: Neuroactive ligand-receptor interaction Prednisone 💬 Prednisone 54件: 2, 11, 13, 14, 18, 19, 26, 28, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 60, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 90, 93, 95, 96, 97, 113, 145, 162, 164, 205, 222, 224, 228, 251, 269, 283, 285, 288, 299, 300, 303, 307, 331 💬
35 SIGMAR1 💬 2件: Amyotrophic lateral sclerosis, Pathways of neurodegeneration - multiple diseases Fenfluramine 💬 Fenfluramine 4件: 140, 144, 145, 149 💬
36 SIGMAR1 💬 2件: Amyotrophic lateral sclerosis, Pathways of neurodegeneration - multiple diseases Fenfluramine hydrochloride 💬 Fenfluramine 4件: 140, 144, 145, 149 💬
37 SLC6A4 💬 3件: Neuroactive ligand signaling, Synaptic vesicle cycle, Serotonergic synapse Fenfluramine hydrochloride 💬 Fenfluramine 4件: 140, 144, 145, 149 💬
38 SLC6A4 💬 3件: Neuroactive ligand signaling, Synaptic vesicle cycle, Serotonergic synapse Fenfluramine 💬 Fenfluramine 4件: 140, 144, 145, 149 💬