Target Gene/Pathway Pathway / Gene

  

Search results

No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank Disease ID
1 AMY 💬 [4] Starch and sucrose metabolism, Salivary secretion, Pancreatic secretion, Carbohydrate digestion and absorption Acarbose 💬 Acarbose [1] 298 💬
2 AMY 💬 [4] Starch and sucrose metabolism, Salivary secretion, Pancreatic secretion, Carbohydrate digestion and absorption Acarbose 💬 Acarbose [1] 298 💬
3 ATP4A 💬 [3] Oxidative phosphorylation, Collecting duct acid secretion, Gastric acid secretion Esomeprazole magnesium 💬 Esomeprazole [10] 6, 13, 46, 86, 98, 107, 113, 234, 298, 299 💬
4 ATP4A 💬 [3] Oxidative phosphorylation, Collecting duct acid secretion, Gastric acid secretion Omeprazole 💬 Omeprazole [16] 6, 13, 21, 46, 51, 85, 90, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬
5 ATP4A 💬 [3] Oxidative phosphorylation, Collecting duct acid secretion, Gastric acid secretion Omeprazole magnesium 💬 Omeprazole [16] 6, 13, 21, 46, 51, 85, 90, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬
6 ATP4A 💬 [3] Oxidative phosphorylation, Collecting duct acid secretion, Gastric acid secretion Esomeprazole 💬 Esomeprazole [10] 6, 13, 46, 86, 98, 107, 113, 234, 298, 299 💬
7 ATP4A 💬 [3] Oxidative phosphorylation, Collecting duct acid secretion, Gastric acid secretion Esomeprazole strontium 💬 Esomeprazole [10] 6, 13, 46, 86, 98, 107, 113, 234, 298, 299 💬
8 ATP4A 💬 [3] Oxidative phosphorylation, Collecting duct acid secretion, Gastric acid secretion Omeprazole sodium 💬 Omeprazole [16] 6, 13, 21, 46, 51, 85, 90, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬
9 ATP4A 💬 [3] Oxidative phosphorylation, Collecting duct acid secretion, Gastric acid secretion Esomeprazole sodium 💬 Esomeprazole [10] 6, 13, 46, 86, 98, 107, 113, 234, 298, 299 💬
10 ATP4A 💬 [3] Oxidative phosphorylation, Collecting duct acid secretion, Gastric acid secretion Esomeprazole magnesium dihydrate 💬 Esomeprazole [10] 6, 13, 46, 86, 98, 107, 113, 234, 298, 299 💬
11 ATP4B 💬 [3] Oxidative phosphorylation, Collecting duct acid secretion, Gastric acid secretion Omeprazole magnesium 💬 Omeprazole [16] 6, 13, 21, 46, 51, 85, 90, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬
12 ATP4B 💬 [3] Oxidative phosphorylation, Collecting duct acid secretion, Gastric acid secretion Esomeprazole magnesium dihydrate 💬 Esomeprazole [10] 6, 13, 46, 86, 98, 107, 113, 234, 298, 299 💬
13 ATP4B 💬 [3] Oxidative phosphorylation, Collecting duct acid secretion, Gastric acid secretion Esomeprazole strontium 💬 Esomeprazole [10] 6, 13, 46, 86, 98, 107, 113, 234, 298, 299 💬
14 ATP4B 💬 [3] Oxidative phosphorylation, Collecting duct acid secretion, Gastric acid secretion Esomeprazole sodium 💬 Esomeprazole [10] 6, 13, 46, 86, 98, 107, 113, 234, 298, 299 💬
15 ATP4B 💬 [3] Oxidative phosphorylation, Collecting duct acid secretion, Gastric acid secretion Omeprazole sodium 💬 Omeprazole [16] 6, 13, 21, 46, 51, 85, 90, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬
16 ATP4B 💬 [3] Oxidative phosphorylation, Collecting duct acid secretion, Gastric acid secretion Esomeprazole magnesium 💬 Esomeprazole [10] 6, 13, 46, 86, 98, 107, 113, 234, 298, 299 💬
17 ATP4B 💬 [3] Oxidative phosphorylation, Collecting duct acid secretion, Gastric acid secretion Esomeprazole 💬 Esomeprazole [10] 6, 13, 46, 86, 98, 107, 113, 234, 298, 299 💬
18 ATP4B 💬 [3] Oxidative phosphorylation, Collecting duct acid secretion, Gastric acid secretion Omeprazole 💬 Omeprazole [16] 6, 13, 21, 46, 51, 85, 90, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬
19 CACNA1C 💬 [34] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Circadian entrainment, Long-term potentiation, Retrograde endocannabinoid signaling, Glutamatergic synapse, Cholinergic synapse, Serotonergic synapse, GABAergic synapse, Dopaminergic synapse, Taste transduction, Insulin secretion, GnRH signaling pathway, Oxytocin signaling pathway, Renin secretion, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Type II diabetes mellitus, Cushing syndrome, Growth hormone synthesis, secretion and action, Alzheimer disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Chemical carcinogenesis - receptor activation, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Amlodipine maleate 💬 Amlodipine [3] 51, 67, 298 💬
20 CACNA1C 💬 [34] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Circadian entrainment, Long-term potentiation, Retrograde endocannabinoid signaling, Glutamatergic synapse, Cholinergic synapse, Serotonergic synapse, GABAergic synapse, Dopaminergic synapse, Taste transduction, Insulin secretion, GnRH signaling pathway, Oxytocin signaling pathway, Renin secretion, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Type II diabetes mellitus, Cushing syndrome, Growth hormone synthesis, secretion and action, Alzheimer disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Chemical carcinogenesis - receptor activation, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Amlodipine benzoate 💬 Amlodipine [3] 51, 67, 298 💬
21 CACNA1C 💬 [34] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Circadian entrainment, Long-term potentiation, Retrograde endocannabinoid signaling, Glutamatergic synapse, Cholinergic synapse, Serotonergic synapse, GABAergic synapse, Dopaminergic synapse, Taste transduction, Insulin secretion, GnRH signaling pathway, Oxytocin signaling pathway, Renin secretion, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Type II diabetes mellitus, Cushing syndrome, Growth hormone synthesis, secretion and action, Alzheimer disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Chemical carcinogenesis - receptor activation, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Amlodipine besylate 💬 Amlodipine [3] 51, 67, 298 💬
22 CACNA1C 💬 [34] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Circadian entrainment, Long-term potentiation, Retrograde endocannabinoid signaling, Glutamatergic synapse, Cholinergic synapse, Serotonergic synapse, GABAergic synapse, Dopaminergic synapse, Taste transduction, Insulin secretion, GnRH signaling pathway, Oxytocin signaling pathway, Renin secretion, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Type II diabetes mellitus, Cushing syndrome, Growth hormone synthesis, secretion and action, Alzheimer disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Chemical carcinogenesis - receptor activation, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Amlodipine 💬 Amlodipine [3] 51, 67, 298 💬
23 CACNA1D 💬 [35] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Cellular senescence, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Tight junction, Circadian entrainment, Retrograde endocannabinoid signaling, Glutamatergic synapse, Cholinergic synapse, Serotonergic synapse, GABAergic synapse, Dopaminergic synapse, Insulin secretion, GnRH signaling pathway, Oxytocin signaling pathway, Renin secretion, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Type II diabetes mellitus, Cushing syndrome, Growth hormone synthesis, secretion and action, Carbohydrate digestion and absorption, Alzheimer disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Chemical carcinogenesis - receptor activation, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Amlodipine benzoate 💬 Amlodipine [3] 51, 67, 298 💬
24 CACNA1D 💬 [35] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Cellular senescence, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Tight junction, Circadian entrainment, Retrograde endocannabinoid signaling, Glutamatergic synapse, Cholinergic synapse, Serotonergic synapse, GABAergic synapse, Dopaminergic synapse, Insulin secretion, GnRH signaling pathway, Oxytocin signaling pathway, Renin secretion, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Type II diabetes mellitus, Cushing syndrome, Growth hormone synthesis, secretion and action, Carbohydrate digestion and absorption, Alzheimer disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Chemical carcinogenesis - receptor activation, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Amlodipine maleate 💬 Amlodipine [3] 51, 67, 298 💬
25 CACNA1D 💬 [35] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Cellular senescence, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Tight junction, Circadian entrainment, Retrograde endocannabinoid signaling, Glutamatergic synapse, Cholinergic synapse, Serotonergic synapse, GABAergic synapse, Dopaminergic synapse, Insulin secretion, GnRH signaling pathway, Oxytocin signaling pathway, Renin secretion, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Type II diabetes mellitus, Cushing syndrome, Growth hormone synthesis, secretion and action, Carbohydrate digestion and absorption, Alzheimer disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Chemical carcinogenesis - receptor activation, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Amlodipine besylate 💬 Amlodipine [3] 51, 67, 298 💬
26 CACNA1D 💬 [35] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Cellular senescence, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Tight junction, Circadian entrainment, Retrograde endocannabinoid signaling, Glutamatergic synapse, Cholinergic synapse, Serotonergic synapse, GABAergic synapse, Dopaminergic synapse, Insulin secretion, GnRH signaling pathway, Oxytocin signaling pathway, Renin secretion, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Type II diabetes mellitus, Cushing syndrome, Growth hormone synthesis, secretion and action, Carbohydrate digestion and absorption, Alzheimer disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Chemical carcinogenesis - receptor activation, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Amlodipine 💬 Amlodipine [3] 51, 67, 298 💬
27 CACNA1F 💬 [27] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Cholinergic synapse, Serotonergic synapse, GABAergic synapse, Insulin secretion, GnRH signaling pathway, Oxytocin signaling pathway, Renin secretion, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Cushing syndrome, Growth hormone synthesis, secretion and action, Alzheimer disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Chemical carcinogenesis - receptor activation, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Amlodipine 💬 Amlodipine [3] 51, 67, 298 💬
28 CACNA1F 💬 [27] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Cholinergic synapse, Serotonergic synapse, GABAergic synapse, Insulin secretion, GnRH signaling pathway, Oxytocin signaling pathway, Renin secretion, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Cushing syndrome, Growth hormone synthesis, secretion and action, Alzheimer disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Chemical carcinogenesis - receptor activation, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Amlodipine besylate 💬 Amlodipine [3] 51, 67, 298 💬
29 CACNA1F 💬 [27] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Cholinergic synapse, Serotonergic synapse, GABAergic synapse, Insulin secretion, GnRH signaling pathway, Oxytocin signaling pathway, Renin secretion, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Cushing syndrome, Growth hormone synthesis, secretion and action, Alzheimer disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Chemical carcinogenesis - receptor activation, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Amlodipine maleate 💬 Amlodipine [3] 51, 67, 298 💬
30 CACNA1F 💬 [27] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Cholinergic synapse, Serotonergic synapse, GABAergic synapse, Insulin secretion, GnRH signaling pathway, Oxytocin signaling pathway, Renin secretion, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Cushing syndrome, Growth hormone synthesis, secretion and action, Alzheimer disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Chemical carcinogenesis - receptor activation, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Amlodipine benzoate 💬 Amlodipine [3] 51, 67, 298 💬
31 CACNA1S 💬 [27] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Cholinergic synapse, Serotonergic synapse, GABAergic synapse, Insulin secretion, GnRH signaling pathway, Oxytocin signaling pathway, Renin secretion, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Cushing syndrome, Growth hormone synthesis, secretion and action, Alzheimer disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Chemical carcinogenesis - receptor activation, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Amlodipine besylate 💬 Amlodipine [3] 51, 67, 298 💬
32 CACNA1S 💬 [27] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Cholinergic synapse, Serotonergic synapse, GABAergic synapse, Insulin secretion, GnRH signaling pathway, Oxytocin signaling pathway, Renin secretion, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Cushing syndrome, Growth hormone synthesis, secretion and action, Alzheimer disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Chemical carcinogenesis - receptor activation, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Amlodipine maleate 💬 Amlodipine [3] 51, 67, 298 💬
33 CACNA1S 💬 [27] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Cholinergic synapse, Serotonergic synapse, GABAergic synapse, Insulin secretion, GnRH signaling pathway, Oxytocin signaling pathway, Renin secretion, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Cushing syndrome, Growth hormone synthesis, secretion and action, Alzheimer disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Chemical carcinogenesis - receptor activation, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Amlodipine benzoate 💬 Amlodipine [3] 51, 67, 298 💬
34 CACNA1S 💬 [27] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Cholinergic synapse, Serotonergic synapse, GABAergic synapse, Insulin secretion, GnRH signaling pathway, Oxytocin signaling pathway, Renin secretion, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Cushing syndrome, Growth hormone synthesis, secretion and action, Alzheimer disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Chemical carcinogenesis - receptor activation, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Pinaverium bromide 💬 Pinaverium [1] 298 💬
35 CACNA1S 💬 [27] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Cholinergic synapse, Serotonergic synapse, GABAergic synapse, Insulin secretion, GnRH signaling pathway, Oxytocin signaling pathway, Renin secretion, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Cushing syndrome, Growth hormone synthesis, secretion and action, Alzheimer disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Chemical carcinogenesis - receptor activation, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Amlodipine 💬 Amlodipine [3] 51, 67, 298 💬
36 CACNA2D1 💬 [7] MAPK signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Oxytocin signaling pathway, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Pregabalin 💬 Pregabalin [5] 13, 36, 46, 70, 298 💬
37 CACNA2D1 💬 [7] MAPK signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Oxytocin signaling pathway, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Gabapentin 💬 Gabapentin [5] 6, 13, 19, 70, 298 💬
38 CACNA2D2 💬 [7] MAPK signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Oxytocin signaling pathway, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Pregabalin 💬 Pregabalin [5] 13, 36, 46, 70, 298 💬
39 CACNA2D2 💬 [7] MAPK signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Oxytocin signaling pathway, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Gabapentin 💬 Gabapentin [5] 6, 13, 19, 70, 298 💬
40 CACNA2D3 💬 [7] MAPK signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Oxytocin signaling pathway, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Pregabalin 💬 Pregabalin [5] 13, 36, 46, 70, 298 💬
41 CACNA2D3 💬 [7] MAPK signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Oxytocin signaling pathway, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Gabapentin 💬 Gabapentin [5] 6, 13, 19, 70, 298 💬
42 CACNA2D4 💬 [7] MAPK signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Oxytocin signaling pathway, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Pregabalin 💬 Pregabalin [5] 13, 36, 46, 70, 298 💬
43 CACNA2D4 💬 [7] MAPK signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Oxytocin signaling pathway, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Gabapentin 💬 Gabapentin [5] 6, 13, 19, 70, 298 💬
44 CCKBR 💬 [4] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Gastric acid secretion Proglumide 💬 Proglumide [1] 298 💬
45 CNR1 💬 [4] Rap1 signaling pathway, Neuroactive ligand-receptor interaction, Thermogenesis, Retrograde endocannabinoid signaling Dronabinol 💬 Dronabinol [8] 2, 8, 13, 36, 46, 96, 271, 298 💬
46 CNR2 💬 [1] Neuroactive ligand-receptor interaction Dronabinol 💬 Dronabinol [8] 2, 8, 13, 36, 46, 96, 271, 298 💬
47 CXCR1 💬 [6] Cytokine-cytokine receptor interaction, Viral protein interaction with cytokine and cytokine receptor, Chemokine signaling pathway, Phospholipase D signaling pathway, Endocytosis, Epithelial cell signaling in Helicobacter pylori infection Reparixin 💬 Reparixin [2] 298, 299 💬
48 CXCR2 💬 [7] Cytokine-cytokine receptor interaction, Viral protein interaction with cytokine and cytokine receptor, Chemokine signaling pathway, Phospholipase D signaling pathway, Endocytosis, Epithelial cell signaling in Helicobacter pylori infection, Human cytomegalovirus infection Reparixin 💬 Reparixin [2] 298, 299 💬
49 GAA 💬 [3] Galactose metabolism, Starch and sucrose metabolism, Lysosome Acarbose 💬 Acarbose [1] 298 💬
50 GABRA 💬 [7] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Midazolam 💬 Midazolam [13] 2, 3, 6, 13, 21, 46, 67, 96, 97, 231, 272, 298, 299 💬
51 GABRA 💬 [7] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Diazepam 💬 Diazepam [3] 46, 155, 298 💬
52 GABRA 💬 [7] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Diazepam 💬 Diazepam [3] 46, 155, 298 💬
53 GABRA 💬 [7] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Midazolam hydrochloride 💬 Midazolam [13] 2, 3, 6, 13, 21, 46, 67, 96, 97, 231, 272, 298, 299 💬
54 GABRA 💬 [7] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Midazolam hydrochloride 💬 Midazolam [13] 2, 3, 6, 13, 21, 46, 67, 96, 97, 231, 272, 298, 299 💬
55 GABRA 💬 [7] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Diazepam 💬 Diazepam [3] 46, 155, 298 💬
56 GABRA 💬 [7] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Midazolam hydrochloride 💬 Midazolam [13] 2, 3, 6, 13, 21, 46, 67, 96, 97, 231, 272, 298, 299 💬
57 GABRA 💬 [7] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Midazolam hydrochloride 💬 Midazolam [13] 2, 3, 6, 13, 21, 46, 67, 96, 97, 231, 272, 298, 299 💬
58 GABRA 💬 [7] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Midazolam maleate 💬 Midazolam [13] 2, 3, 6, 13, 21, 46, 67, 96, 97, 231, 272, 298, 299 💬
59 GABRA 💬 [7] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Diazepam 💬 Diazepam [3] 46, 155, 298 💬
60 GABRA 💬 [7] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Diazepam 💬 Diazepam [3] 46, 155, 298 💬
61 GABRA 💬 [7] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Midazolam maleate 💬 Midazolam [13] 2, 3, 6, 13, 21, 46, 67, 96, 97, 231, 272, 298, 299 💬
62 GABRA 💬 [7] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Midazolam maleate 💬 Midazolam [13] 2, 3, 6, 13, 21, 46, 67, 96, 97, 231, 272, 298, 299 💬
63 GABRA 💬 [7] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Midazolam hydrochloride 💬 Midazolam [13] 2, 3, 6, 13, 21, 46, 67, 96, 97, 231, 272, 298, 299 💬
64 GABRA 💬 [7] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Midazolam 💬 Midazolam [13] 2, 3, 6, 13, 21, 46, 67, 96, 97, 231, 272, 298, 299 💬
65 GABRA 💬 [7] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Midazolam 💬 Midazolam [13] 2, 3, 6, 13, 21, 46, 67, 96, 97, 231, 272, 298, 299 💬
66 GABRA 💬 [7] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Midazolam 💬 Midazolam [13] 2, 3, 6, 13, 21, 46, 67, 96, 97, 231, 272, 298, 299 💬
67 GABRA 💬 [7] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Midazolam 💬 Midazolam [13] 2, 3, 6, 13, 21, 46, 67, 96, 97, 231, 272, 298, 299 💬
68 GABRA 💬 [7] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Midazolam maleate 💬 Midazolam [13] 2, 3, 6, 13, 21, 46, 67, 96, 97, 231, 272, 298, 299 💬
69 GABRA 💬 [7] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Diazepam 💬 Diazepam [3] 46, 155, 298 💬
70 GABRA 💬 [7] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Midazolam hydrochloride 💬 Midazolam [13] 2, 3, 6, 13, 21, 46, 67, 96, 97, 231, 272, 298, 299 💬
71 GABRA 💬 [7] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Midazolam 💬 Midazolam [13] 2, 3, 6, 13, 21, 46, 67, 96, 97, 231, 272, 298, 299 💬
72 GABRA 💬 [7] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Midazolam maleate 💬 Midazolam [13] 2, 3, 6, 13, 21, 46, 67, 96, 97, 231, 272, 298, 299 💬
73 GABRA 💬 [7] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Midazolam maleate 💬 Midazolam [13] 2, 3, 6, 13, 21, 46, 67, 96, 97, 231, 272, 298, 299 💬
74 GABRB 💬 [7] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Retrograde endocannabinoid signaling, Serotonergic synapse, GABAergic synapse, Morphine addiction, Nicotine addiction Diazepam 💬 Diazepam [3] 46, 155, 298 💬
75 GABRB 💬 [7] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Retrograde endocannabinoid signaling, Serotonergic synapse, GABAergic synapse, Morphine addiction, Nicotine addiction Diazepam 💬 Diazepam [3] 46, 155, 298 💬
76 GABRB 💬 [7] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Retrograde endocannabinoid signaling, Serotonergic synapse, GABAergic synapse, Morphine addiction, Nicotine addiction Midazolam maleate 💬 Midazolam [13] 2, 3, 6, 13, 21, 46, 67, 96, 97, 231, 272, 298, 299 💬
77 GABRB 💬 [7] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Retrograde endocannabinoid signaling, Serotonergic synapse, GABAergic synapse, Morphine addiction, Nicotine addiction Midazolam 💬 Midazolam [13] 2, 3, 6, 13, 21, 46, 67, 96, 97, 231, 272, 298, 299 💬
78 GABRB 💬 [7] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Retrograde endocannabinoid signaling, Serotonergic synapse, GABAergic synapse, Morphine addiction, Nicotine addiction Midazolam hydrochloride 💬 Midazolam [13] 2, 3, 6, 13, 21, 46, 67, 96, 97, 231, 272, 298, 299 💬
79 GABRB 💬 [7] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Retrograde endocannabinoid signaling, Serotonergic synapse, GABAergic synapse, Morphine addiction, Nicotine addiction Midazolam hydrochloride 💬 Midazolam [13] 2, 3, 6, 13, 21, 46, 67, 96, 97, 231, 272, 298, 299 💬
80 GABRB 💬 [7] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Retrograde endocannabinoid signaling, Serotonergic synapse, GABAergic synapse, Morphine addiction, Nicotine addiction Midazolam hydrochloride 💬 Midazolam [13] 2, 3, 6, 13, 21, 46, 67, 96, 97, 231, 272, 298, 299 💬
81 GABRB 💬 [7] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Retrograde endocannabinoid signaling, Serotonergic synapse, GABAergic synapse, Morphine addiction, Nicotine addiction Midazolam 💬 Midazolam [13] 2, 3, 6, 13, 21, 46, 67, 96, 97, 231, 272, 298, 299 💬
82 GABRB 💬 [7] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Retrograde endocannabinoid signaling, Serotonergic synapse, GABAergic synapse, Morphine addiction, Nicotine addiction Diazepam 💬 Diazepam [3] 46, 155, 298 💬
83 GABRB 💬 [7] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Retrograde endocannabinoid signaling, Serotonergic synapse, GABAergic synapse, Morphine addiction, Nicotine addiction Midazolam maleate 💬 Midazolam [13] 2, 3, 6, 13, 21, 46, 67, 96, 97, 231, 272, 298, 299 💬
84 GABRB 💬 [7] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Retrograde endocannabinoid signaling, Serotonergic synapse, GABAergic synapse, Morphine addiction, Nicotine addiction Midazolam 💬 Midazolam [13] 2, 3, 6, 13, 21, 46, 67, 96, 97, 231, 272, 298, 299 💬
85 GABRB 💬 [7] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Retrograde endocannabinoid signaling, Serotonergic synapse, GABAergic synapse, Morphine addiction, Nicotine addiction Midazolam maleate 💬 Midazolam [13] 2, 3, 6, 13, 21, 46, 67, 96, 97, 231, 272, 298, 299 💬
86 GABRD 💬 [6] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Midazolam 💬 Midazolam [13] 2, 3, 6, 13, 21, 46, 67, 96, 97, 231, 272, 298, 299 💬
87 GABRD 💬 [6] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Diazepam 💬 Diazepam [3] 46, 155, 298 💬
88 GABRD 💬 [6] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Midazolam maleate 💬 Midazolam [13] 2, 3, 6, 13, 21, 46, 67, 96, 97, 231, 272, 298, 299 💬
89 GABRD 💬 [6] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Midazolam hydrochloride 💬 Midazolam [13] 2, 3, 6, 13, 21, 46, 67, 96, 97, 231, 272, 298, 299 💬
90 GABRE 💬 [6] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Midazolam maleate 💬 Midazolam [13] 2, 3, 6, 13, 21, 46, 67, 96, 97, 231, 272, 298, 299 💬
91 GABRE 💬 [6] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Midazolam hydrochloride 💬 Midazolam [13] 2, 3, 6, 13, 21, 46, 67, 96, 97, 231, 272, 298, 299 💬
92 GABRE 💬 [6] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Midazolam 💬 Midazolam [13] 2, 3, 6, 13, 21, 46, 67, 96, 97, 231, 272, 298, 299 💬
93 GABRE 💬 [6] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Diazepam 💬 Diazepam [3] 46, 155, 298 💬
94 GABRG 💬 [6] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Midazolam hydrochloride 💬 Midazolam [13] 2, 3, 6, 13, 21, 46, 67, 96, 97, 231, 272, 298, 299 💬
95 GABRG 💬 [6] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Diazepam 💬 Diazepam [3] 46, 155, 298 💬
96 GABRG 💬 [6] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Midazolam hydrochloride 💬 Midazolam [13] 2, 3, 6, 13, 21, 46, 67, 96, 97, 231, 272, 298, 299 💬
97 GABRG 💬 [6] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Midazolam 💬 Midazolam [13] 2, 3, 6, 13, 21, 46, 67, 96, 97, 231, 272, 298, 299 💬
98 GABRG 💬 [6] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Midazolam 💬 Midazolam [13] 2, 3, 6, 13, 21, 46, 67, 96, 97, 231, 272, 298, 299 💬
99 GABRG 💬 [6] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Diazepam 💬 Diazepam [3] 46, 155, 298 💬
100 GABRG 💬 [6] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Midazolam maleate 💬 Midazolam [13] 2, 3, 6, 13, 21, 46, 67, 96, 97, 231, 272, 298, 299 💬
101 GABRG 💬 [6] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Midazolam hydrochloride 💬 Midazolam [13] 2, 3, 6, 13, 21, 46, 67, 96, 97, 231, 272, 298, 299 💬
102 GABRG 💬 [6] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Midazolam maleate 💬 Midazolam [13] 2, 3, 6, 13, 21, 46, 67, 96, 97, 231, 272, 298, 299 💬
103 GABRG 💬 [6] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Midazolam 💬 Midazolam [13] 2, 3, 6, 13, 21, 46, 67, 96, 97, 231, 272, 298, 299 💬
104 GABRG 💬 [6] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Diazepam 💬 Diazepam [3] 46, 155, 298 💬
105 GABRG 💬 [6] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Midazolam maleate 💬 Midazolam [13] 2, 3, 6, 13, 21, 46, 67, 96, 97, 231, 272, 298, 299 💬
106 GABRP 💬 [6] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Midazolam hydrochloride 💬 Midazolam [13] 2, 3, 6, 13, 21, 46, 67, 96, 97, 231, 272, 298, 299 💬
107 GABRP 💬 [6] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Diazepam 💬 Diazepam [3] 46, 155, 298 💬
108 GABRP 💬 [6] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Midazolam 💬 Midazolam [13] 2, 3, 6, 13, 21, 46, 67, 96, 97, 231, 272, 298, 299 💬
109 GABRP 💬 [6] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Midazolam maleate 💬 Midazolam [13] 2, 3, 6, 13, 21, 46, 67, 96, 97, 231, 272, 298, 299 💬
110 GABRQ 💬 [6] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Diazepam 💬 Diazepam [3] 46, 155, 298 💬
111 GABRQ 💬 [6] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Midazolam hydrochloride 💬 Midazolam [13] 2, 3, 6, 13, 21, 46, 67, 96, 97, 231, 272, 298, 299 💬
112 GABRQ 💬 [6] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Midazolam maleate 💬 Midazolam [13] 2, 3, 6, 13, 21, 46, 67, 96, 97, 231, 272, 298, 299 💬
113 GABRQ 💬 [6] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Midazolam 💬 Midazolam [13] 2, 3, 6, 13, 21, 46, 67, 96, 97, 231, 272, 298, 299 💬
114 GANC 💬 [2] Galactose metabolism, Starch and sucrose metabolism Acarbose 💬 Acarbose [1] 298 💬
115 HMGCR 💬 [3] Terpenoid backbone biosynthesis, AMPK signaling pathway, Bile secretion Simvastatin 💬 Simvastatin [21] 6, 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬
116 IL6R 💬 [11] Cytokine-cytokine receptor interaction, Viral protein interaction with cytokine and cytokine receptor, HIF-1 signaling pathway, PI3K-Akt signaling pathway, JAK-STAT signaling pathway, Hematopoietic cell lineage, Th17 cell differentiation, Non-alcoholic fatty liver disease, Human cytomegalovirus infection, Coronavirus disease - COVID-19, Pathways in cancer Tocilizumab 💬 Tocilizumab [24] 2, 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 149, 153, 266, 271, 298, 331 💬
117 LTA 💬 [7] Cytokine-cytokine receptor interaction, Viral protein interaction with cytokine and cytokine receptor, NF-kappa B signaling pathway, TNF signaling pathway, Type I diabetes mellitus, Human T-cell leukemia virus 1 infection, Herpes simplex virus 1 infection Etanercept 💬 Etanercept [16] 15, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
118 MGAM 💬 [3] Galactose metabolism, Starch and sucrose metabolism, Carbohydrate digestion and absorption Acarbose 💬 Acarbose [1] 298 💬
119 NGFB 💬 [9] MAPK signaling pathway, Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, Cytokine-cytokine receptor interaction, PI3K-Akt signaling pathway, Apoptosis, Neurotrophin signaling pathway, Inflammatory mediator regulation of TRP channels Tanezumab 💬 Tanezumab [2] 226, 298 💬
120 NR1C3 💬 [12] PPAR signaling pathway, Efferocytosis, AMPK signaling pathway, Longevity regulating pathway, Osteoclast differentiation, Thermogenesis, Non-alcoholic fatty liver disease, Huntington disease, Pathways in cancer, Transcriptional misregulation in cancer, Thyroid cancer, Lipid and atherosclerosis Pioglitazone hydrochloride 💬 Pioglitazone [17] 2, 6, 13, 15, 20, 46, 49, 65, 67, 81, 86, 96, 220, 229, 265, 298, 299 💬
121 NR1C3 💬 [12] PPAR signaling pathway, Efferocytosis, AMPK signaling pathway, Longevity regulating pathway, Osteoclast differentiation, Thermogenesis, Non-alcoholic fatty liver disease, Huntington disease, Pathways in cancer, Transcriptional misregulation in cancer, Thyroid cancer, Lipid and atherosclerosis Pioglitazone 💬 Pioglitazone [17] 2, 6, 13, 15, 20, 46, 49, 65, 67, 81, 86, 96, 220, 229, 265, 298, 299 💬
122 NR3C1 💬 [1] Neuroactive ligand-receptor interaction Triamcinolone 💬 Triamcinolone [10] 35, 46, 53, 56, 70, 90, 96, 107, 226, 298 💬
123 NR3C1 💬 [1] Neuroactive ligand-receptor interaction Triamcinolone hexacetonide 💬 Triamcinolone [10] 35, 46, 53, 56, 70, 90, 96, 107, 226, 298 💬
124 NR3C1 💬 [1] Neuroactive ligand-receptor interaction Triamcinolone acetonide 💬 Triamcinolone [10] 35, 46, 53, 56, 70, 90, 96, 107, 226, 298 💬
125 NR3C1 💬 [1] Neuroactive ligand-receptor interaction Triamcinolone diacetate 💬 Triamcinolone [10] 35, 46, 53, 56, 70, 90, 96, 107, 226, 298 💬
126 OPRD1 💬 [5] cGMP-PKG signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling Oxycodone terephthalate 💬 Oxycodone [6] 6, 46, 70, 226, 231, 298 💬
127 OPRD1 💬 [5] cGMP-PKG signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling Oxycodone 💬 Oxycodone [6] 6, 46, 70, 226, 231, 298 💬
128 OPRD1 💬 [5] cGMP-PKG signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling Oxycodone hydrochloride 💬 Oxycodone [6] 6, 46, 70, 226, 231, 298 💬
129 OPRK1 💬 [3] Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling Buprenorphine hydrochloride 💬 Buprenorphine [3] 46, 70, 298 💬
130 OPRK1 💬 [3] Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling Buprenorphine 💬 Buprenorphine [3] 46, 70, 298 💬
131 OPRK1 💬 [3] Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling Oxycodone 💬 Oxycodone [6] 6, 46, 70, 226, 231, 298 💬
132 OPRK1 💬 [3] Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling Oxycodone terephthalate 💬 Oxycodone [6] 6, 46, 70, 226, 231, 298 💬
133 OPRK1 💬 [3] Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling Oxycodone hydrochloride 💬 Oxycodone [6] 6, 46, 70, 226, 231, 298 💬
134 OPRM1 💬 [5] Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Estrogen signaling pathway, Morphine addiction Fentanyl citrate 💬 Fentanyl [6] 46, 70, 97, 215, 231, 298 💬
135 OPRM1 💬 [5] Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Estrogen signaling pathway, Morphine addiction Oxycodone hydrochloride 💬 Oxycodone [6] 6, 46, 70, 226, 231, 298 💬
136 OPRM1 💬 [5] Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Estrogen signaling pathway, Morphine addiction Fentanyl 💬 Fentanyl [6] 46, 70, 97, 215, 231, 298 💬
137 OPRM1 💬 [5] Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Estrogen signaling pathway, Morphine addiction Morphine tartrate 💬 Morphine [6] 36, 46, 70, 85, 86, 298 💬
138 OPRM1 💬 [5] Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Estrogen signaling pathway, Morphine addiction Buprenorphine 💬 Buprenorphine [3] 46, 70, 298 💬
139 OPRM1 💬 [5] Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Estrogen signaling pathway, Morphine addiction Oxycodone 💬 Oxycodone [6] 6, 46, 70, 226, 231, 298 💬
140 OPRM1 💬 [5] Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Estrogen signaling pathway, Morphine addiction Fentanyl hydrochloride 💬 Fentanyl [6] 46, 70, 97, 215, 231, 298 💬
141 OPRM1 💬 [5] Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Estrogen signaling pathway, Morphine addiction Morphine hydrochloride hydrate 💬 Morphine [6] 36, 46, 70, 85, 86, 298 💬
142 OPRM1 💬 [5] Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Estrogen signaling pathway, Morphine addiction Meperidine hydrochloride 💬 Meperidine [2] 97, 298 💬
143 OPRM1 💬 [5] Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Estrogen signaling pathway, Morphine addiction Pethidine 💬 Meperidine [2] 97, 298 💬
144 OPRM1 💬 [5] Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Estrogen signaling pathway, Morphine addiction Morphine 💬 Morphine [6] 36, 46, 70, 85, 86, 298 💬
145 OPRM1 💬 [5] Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Estrogen signaling pathway, Morphine addiction Buprenorphine hydrochloride 💬 Buprenorphine [3] 46, 70, 298 💬
146 OPRM1 💬 [5] Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Estrogen signaling pathway, Morphine addiction Morphine sulfate 💬 Morphine [6] 36, 46, 70, 85, 86, 298 💬
147 OPRM1 💬 [5] Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Estrogen signaling pathway, Morphine addiction Oxycodone terephthalate 💬 Oxycodone [6] 6, 46, 70, 226, 231, 298 💬
148 PRKAA 💬 [20] FoxO signaling pathway, Autophagy - animal, mTOR signaling pathway, PI3K-Akt signaling pathway, AMPK signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Apelin signaling pathway, Tight junction, Circadian rhythm, Thermogenesis, Insulin signaling pathway, Adipocytokine signaling pathway, Oxytocin signaling pathway, Glucagon signaling pathway, Insulin resistance, Non-alcoholic fatty liver disease, Alcoholic liver disease, Hypertrophic cardiomyopathy, Fluid shear stress and atherosclerosis Metformin hydrochloride 💬 Metformin [28] 2, 6, 8, 13, 46, 49, 60, 65, 66, 67, 75, 77, 81, 84, 86, 97, 113, 127, 158, 206, 218, 222, 225, 265, 285, 298, 299, 301 💬
149 PRKAA 💬 [20] FoxO signaling pathway, Autophagy - animal, mTOR signaling pathway, PI3K-Akt signaling pathway, AMPK signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Apelin signaling pathway, Tight junction, Circadian rhythm, Thermogenesis, Insulin signaling pathway, Adipocytokine signaling pathway, Oxytocin signaling pathway, Glucagon signaling pathway, Insulin resistance, Non-alcoholic fatty liver disease, Alcoholic liver disease, Hypertrophic cardiomyopathy, Fluid shear stress and atherosclerosis Metformin hydrochloride 💬 Metformin [28] 2, 6, 8, 13, 46, 49, 60, 65, 66, 67, 75, 77, 81, 84, 86, 97, 113, 127, 158, 206, 218, 222, 225, 265, 285, 298, 299, 301 💬
150 PRKAA 💬 [20] FoxO signaling pathway, Autophagy - animal, mTOR signaling pathway, PI3K-Akt signaling pathway, AMPK signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Apelin signaling pathway, Tight junction, Circadian rhythm, Thermogenesis, Insulin signaling pathway, Adipocytokine signaling pathway, Oxytocin signaling pathway, Glucagon signaling pathway, Insulin resistance, Non-alcoholic fatty liver disease, Alcoholic liver disease, Hypertrophic cardiomyopathy, Fluid shear stress and atherosclerosis Metformin 💬 Metformin [28] 2, 6, 8, 13, 46, 49, 60, 65, 66, 67, 75, 77, 81, 84, 86, 97, 113, 127, 158, 206, 218, 222, 225, 265, 285, 298, 299, 301 💬
151 PRKAA 💬 [20] FoxO signaling pathway, Autophagy - animal, mTOR signaling pathway, PI3K-Akt signaling pathway, AMPK signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Apelin signaling pathway, Tight junction, Circadian rhythm, Thermogenesis, Insulin signaling pathway, Adipocytokine signaling pathway, Oxytocin signaling pathway, Glucagon signaling pathway, Insulin resistance, Non-alcoholic fatty liver disease, Alcoholic liver disease, Hypertrophic cardiomyopathy, Fluid shear stress and atherosclerosis Metformin 💬 Metformin [28] 2, 6, 8, 13, 46, 49, 60, 65, 66, 67, 75, 77, 81, 84, 86, 97, 113, 127, 158, 206, 218, 222, 225, 265, 285, 298, 299, 301 💬
152 PTGS1 💬 [4] Arachidonic acid metabolism, Platelet activation, Serotonergic synapse, Regulation of lipolysis in adipocytes Indomethacin sodium 💬 Indomethacin [3] 225, 271, 298 💬
153 PTGS1 💬 [4] Arachidonic acid metabolism, Platelet activation, Serotonergic synapse, Regulation of lipolysis in adipocytes Indomethacin 💬 Indomethacin [3] 225, 271, 298 💬
154 PTGS2 💬 [22] Arachidonic acid metabolism, NF-kappa B signaling pathway, Efferocytosis, VEGF signaling pathway, C-type lectin receptor signaling pathway, IL-17 signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Ovarian steroidogenesis, Oxytocin signaling pathway, Regulation of lipolysis in adipocytes, Alzheimer disease, Pathways of neurodegeneration - multiple diseases, Leishmaniasis, Human cytomegalovirus infection, Human papillomavirus infection, Kaposi sarcoma-associated herpesvirus infection, Pathways in cancer, Chemical carcinogenesis - DNA adducts, MicroRNAs in cancer, Small cell lung cancer Indomethacin 💬 Indomethacin [3] 225, 271, 298 💬
155 PTGS2 💬 [22] Arachidonic acid metabolism, NF-kappa B signaling pathway, Efferocytosis, VEGF signaling pathway, C-type lectin receptor signaling pathway, IL-17 signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Ovarian steroidogenesis, Oxytocin signaling pathway, Regulation of lipolysis in adipocytes, Alzheimer disease, Pathways of neurodegeneration - multiple diseases, Leishmaniasis, Human cytomegalovirus infection, Human papillomavirus infection, Kaposi sarcoma-associated herpesvirus infection, Pathways in cancer, Chemical carcinogenesis - DNA adducts, MicroRNAs in cancer, Small cell lung cancer Indomethacin sodium 💬 Indomethacin [3] 225, 271, 298 💬
156 SCN1A 💬 [1] Dopaminergic synapse Lidocaine hydrochloride 💬 Lidocaine [14] 6, 13, 22, 34, 46, 51, 70, 86, 107, 168, 226, 231, 256, 298 💬
157 SCN1A 💬 [1] Dopaminergic synapse Lidocaine 💬 Lidocaine [14] 6, 13, 22, 34, 46, 51, 70, 86, 107, 168, 226, 231, 256, 298 💬
158 SCN1A 💬 [1] Dopaminergic synapse Lidocaine hydrochloride monohydrate 💬 Lidocaine [14] 6, 13, 22, 34, 46, 51, 70, 86, 107, 168, 226, 231, 256, 298 💬
159 SCN2A 💬 [1] Taste transduction Lidocaine hydrochloride monohydrate 💬 Lidocaine [14] 6, 13, 22, 34, 46, 51, 70, 86, 107, 168, 226, 231, 256, 298 💬
160 SCN2A 💬 [1] Taste transduction Lidocaine 💬 Lidocaine [14] 6, 13, 22, 34, 46, 51, 70, 86, 107, 168, 226, 231, 256, 298 💬
161 SCN2A 💬 [1] Taste transduction Lidocaine hydrochloride 💬 Lidocaine [14] 6, 13, 22, 34, 46, 51, 70, 86, 107, 168, 226, 231, 256, 298 💬
162 SCN3A 💬 [1] Taste transduction Lidocaine hydrochloride 💬 Lidocaine [14] 6, 13, 22, 34, 46, 51, 70, 86, 107, 168, 226, 231, 256, 298 💬
163 SCN3A 💬 [1] Taste transduction Lacosamide 💬 Lacosamide [4] 2, 46, 149, 298 💬
164 SCN3A 💬 [1] Taste transduction Lidocaine 💬 Lidocaine [14] 6, 13, 22, 34, 46, 51, 70, 86, 107, 168, 226, 231, 256, 298 💬
165 SCN3A 💬 [1] Taste transduction Lidocaine hydrochloride monohydrate 💬 Lidocaine [14] 6, 13, 22, 34, 46, 51, 70, 86, 107, 168, 226, 231, 256, 298 💬
166 SCN5A 💬 [1] Adrenergic signaling in cardiomyocytes Lidocaine 💬 Lidocaine [14] 6, 13, 22, 34, 46, 51, 70, 86, 107, 168, 226, 231, 256, 298 💬
167 SCN5A 💬 [1] Adrenergic signaling in cardiomyocytes Lidocaine hydrochloride 💬 Lidocaine [14] 6, 13, 22, 34, 46, 51, 70, 86, 107, 168, 226, 231, 256, 298 💬
168 SCN5A 💬 [1] Adrenergic signaling in cardiomyocytes Lidocaine hydrochloride monohydrate 💬 Lidocaine [14] 6, 13, 22, 34, 46, 51, 70, 86, 107, 168, 226, 231, 256, 298 💬
169 SCN9A 💬 [1] Taste transduction Lidocaine 💬 Lidocaine [14] 6, 13, 22, 34, 46, 51, 70, 86, 107, 168, 226, 231, 256, 298 💬
170 SCN9A 💬 [1] Taste transduction Lidocaine hydrochloride monohydrate 💬 Lidocaine [14] 6, 13, 22, 34, 46, 51, 70, 86, 107, 168, 226, 231, 256, 298 💬
171 SCN9A 💬 [1] Taste transduction Lidocaine hydrochloride 💬 Lidocaine [14] 6, 13, 22, 34, 46, 51, 70, 86, 107, 168, 226, 231, 256, 298 💬
172 SCN9A 💬 [1] Taste transduction Lacosamide 💬 Lacosamide [4] 2, 46, 149, 298 💬
173 SCTR 💬 [3] Neuroactive ligand-receptor interaction, Pancreatic secretion, Bile secretion Secretin 💬 Secretin human [1] 298 💬
174 SERPINA1 💬 [1] Complement and coagulation cascades alpha 1-Antitrypsin 💬 Alpha-1-proteinase inhibitor [3] 231, 298, 299 💬
175 SLC6A1 💬 [3] Neuroactive ligand signaling, Synaptic vesicle cycle, GABAergic synapse Gabapentin 💬 Gabapentin [5] 6, 13, 19, 70, 298 💬
176 SSTR2 💬 [5] cAMP signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Growth hormone synthesis, secretion and action, Gastric acid secretion Lanreotide acetate 💬 Lanreotide [5] 67, 73, 77, 85, 298 💬
177 SSTR5 💬 [4] cAMP signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Growth hormone synthesis, secretion and action Lanreotide acetate 💬 Lanreotide [5] 67, 73, 77, 85, 298 💬
178 TNF 💬 [66] MAPK signaling pathway, Cytokine-cytokine receptor interaction, Viral protein interaction with cytokine and cytokine receptor, NF-kappa B signaling pathway, Sphingolipid signaling pathway, mTOR signaling pathway, Apoptosis, Necroptosis, TGF-beta signaling pathway, Osteoclast differentiation, Antigen processing and presentation, Toll-like receptor signaling pathway, NOD-like receptor signaling pathway, RIG-I-like receptor signaling pathway, C-type lectin receptor signaling pathway, Hematopoietic cell lineage, Natural killer cell mediated cytotoxicity, IL-17 signaling pathway, T cell receptor signaling pathway, Fc epsilon RI signaling pathway, TNF signaling pathway, Adipocytokine signaling pathway, Type II diabetes mellitus, Insulin resistance, Non-alcoholic fatty liver disease, AGE-RAGE signaling pathway in diabetic complications, Alcoholic liver disease, Type I diabetes mellitus, Alzheimer disease, Amyotrophic lateral sclerosis, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Shigellosis, Salmonella infection, Pertussis, Legionellosis, Yersinia infection, Leishmaniasis, Chagas disease, African trypanosomiasis, Malaria, Toxoplasmosis, Amoebiasis, Tuberculosis, Hepatitis C, Hepatitis B, Human cytomegalovirus infection, Influenza A, Human papillomavirus infection, Human T-cell leukemia virus 1 infection, Herpes simplex virus 1 infection, Epstein-Barr virus infection, Human immunodeficiency virus 1 infection, Coronavirus disease - COVID-19, Proteoglycans in cancer, Asthma, Inflammatory bowel disease, Systemic lupus erythematosus, Rheumatoid arthritis, Allograft rejection, Graft-versus-host disease, Hypertrophic cardiomyopathy, Dilated cardiomyopathy, Lipid and atherosclerosis, Fluid shear stress and atherosclerosis Thalidomide 💬 Thalidomide [21] 2, 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 117, 227, 271, 280, 298, 300, 331 💬
179 TNF 💬 [66] MAPK signaling pathway, Cytokine-cytokine receptor interaction, Viral protein interaction with cytokine and cytokine receptor, NF-kappa B signaling pathway, Sphingolipid signaling pathway, mTOR signaling pathway, Apoptosis, Necroptosis, TGF-beta signaling pathway, Osteoclast differentiation, Antigen processing and presentation, Toll-like receptor signaling pathway, NOD-like receptor signaling pathway, RIG-I-like receptor signaling pathway, C-type lectin receptor signaling pathway, Hematopoietic cell lineage, Natural killer cell mediated cytotoxicity, IL-17 signaling pathway, T cell receptor signaling pathway, Fc epsilon RI signaling pathway, TNF signaling pathway, Adipocytokine signaling pathway, Type II diabetes mellitus, Insulin resistance, Non-alcoholic fatty liver disease, AGE-RAGE signaling pathway in diabetic complications, Alcoholic liver disease, Type I diabetes mellitus, Alzheimer disease, Amyotrophic lateral sclerosis, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Shigellosis, Salmonella infection, Pertussis, Legionellosis, Yersinia infection, Leishmaniasis, Chagas disease, African trypanosomiasis, Malaria, Toxoplasmosis, Amoebiasis, Tuberculosis, Hepatitis C, Hepatitis B, Human cytomegalovirus infection, Influenza A, Human papillomavirus infection, Human T-cell leukemia virus 1 infection, Herpes simplex virus 1 infection, Epstein-Barr virus infection, Human immunodeficiency virus 1 infection, Coronavirus disease - COVID-19, Proteoglycans in cancer, Asthma, Inflammatory bowel disease, Systemic lupus erythematosus, Rheumatoid arthritis, Allograft rejection, Graft-versus-host disease, Hypertrophic cardiomyopathy, Dilated cardiomyopathy, Lipid and atherosclerosis, Fluid shear stress and atherosclerosis Etanercept 💬 Etanercept [16] 15, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
180 VDR 💬 [5] Parathyroid hormone synthesis, secretion and action, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Tuberculosis, Chemical carcinogenesis - receptor activation Cholecalciferol 💬 Cholecalciferol [23] 6, 11, 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 65, 84, 85, 96, 97, 98, 162, 228, 271, 298, 299 💬
181 VDR 💬 [5] Parathyroid hormone synthesis, secretion and action, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Tuberculosis, Chemical carcinogenesis - receptor activation Paricalcitol 💬 Paricalcitol [5] 19, 66, 218, 238, 298 💬