Target Gene/Pathway Pathway / Gene

  

Search results

No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank Disease ID
1 ADORA1 💬 [8] cGMP-PKG signaling pathway, cAMP signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Regulation of lipolysis in adipocytes, Renin secretion, Morphine addiction Caffeine 💬 Caffeine [8] 2, 6, 13, 21, 46, 96, 97, 265 💬
2 ADORA1 💬 [8] cGMP-PKG signaling pathway, cAMP signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Regulation of lipolysis in adipocytes, Renin secretion, Morphine addiction Caffeine citrate 💬 Caffeine [8] 2, 6, 13, 21, 46, 96, 97, 265 💬
3 ADORA2A 💬 [8] Rap1 signaling pathway, Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Vascular smooth muscle contraction, Parkinson disease, Alcoholism Caffeine citrate 💬 Caffeine [8] 2, 6, 13, 21, 46, 96, 97, 265 💬
4 ADORA2A 💬 [8] Rap1 signaling pathway, Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Vascular smooth muscle contraction, Parkinson disease, Alcoholism Caffeine 💬 Caffeine [8] 2, 6, 13, 21, 46, 96, 97, 265 💬
5 ADRA1A 💬 [9] Calcium signaling pathway, cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Salivary secretion Epinephrine 💬 Epinephrine [4] 46, 70, 96, 97 💬
6 ADRA1A 💬 [9] Calcium signaling pathway, cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Salivary secretion Epinephrine bitartrate 💬 Epinephrine [4] 46, 70, 96, 97 💬
7 ADRA1A 💬 [9] Calcium signaling pathway, cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Salivary secretion Epinephrine hydrochloride 💬 Epinephrine [4] 46, 70, 96, 97 💬
8 ADRA1B 💬 [8] Calcium signaling pathway, cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Salivary secretion Epinephrine 💬 Epinephrine [4] 46, 70, 96, 97 💬
9 ADRA1B 💬 [8] Calcium signaling pathway, cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Salivary secretion Epinephrine bitartrate 💬 Epinephrine [4] 46, 70, 96, 97 💬
10 ADRA1B 💬 [8] Calcium signaling pathway, cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Salivary secretion Epinephrine hydrochloride 💬 Epinephrine [4] 46, 70, 96, 97 💬
11 ADRA1D 💬 [8] Calcium signaling pathway, cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Salivary secretion Epinephrine bitartrate 💬 Epinephrine [4] 46, 70, 96, 97 💬
12 ADRA1D 💬 [8] Calcium signaling pathway, cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Salivary secretion Epinephrine hydrochloride 💬 Epinephrine [4] 46, 70, 96, 97 💬
13 ADRA1D 💬 [8] Calcium signaling pathway, cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Salivary secretion Epinephrine 💬 Epinephrine [4] 46, 70, 96, 97 💬
14 ADRA2A 💬 [4] cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling Epinephrine bitartrate 💬 Epinephrine [4] 46, 70, 96, 97 💬
15 ADRA2A 💬 [4] cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling Epinephrine 💬 Epinephrine [4] 46, 70, 96, 97 💬
16 ADRA2A 💬 [4] cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling Mirtazapine 💬 Mirtazapine [4] 6, 85, 97, 156 💬
17 ADRA2A 💬 [4] cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling Epinephrine hydrochloride 💬 Epinephrine [4] 46, 70, 96, 97 💬
18 ADRA2B 💬 [4] cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling Epinephrine bitartrate 💬 Epinephrine [4] 46, 70, 96, 97 💬
19 ADRA2B 💬 [4] cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling Epinephrine 💬 Epinephrine [4] 46, 70, 96, 97 💬
20 ADRA2B 💬 [4] cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling Epinephrine hydrochloride 💬 Epinephrine [4] 46, 70, 96, 97 💬
21 ADRA2B 💬 [4] cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling Mirtazapine 💬 Mirtazapine [4] 6, 85, 97, 156 💬
22 ADRA2C 💬 [4] cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling Mirtazapine 💬 Mirtazapine [4] 6, 85, 97, 156 💬
23 ADRA2C 💬 [4] cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling Epinephrine 💬 Epinephrine [4] 46, 70, 96, 97 💬
24 ADRA2C 💬 [4] cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling Epinephrine hydrochloride 💬 Epinephrine [4] 46, 70, 96, 97 💬
25 ADRA2C 💬 [4] cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling Epinephrine bitartrate 💬 Epinephrine [4] 46, 70, 96, 97 💬
26 ADRB1 💬 [13] Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Adrenergic signaling in cardiomyocytes, Gap junction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy Epinephrine bitartrate 💬 Epinephrine [4] 46, 70, 96, 97 💬
27 ADRB1 💬 [13] Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Adrenergic signaling in cardiomyocytes, Gap junction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy Epinephrine 💬 Epinephrine [4] 46, 70, 96, 97 💬
28 ADRB1 💬 [13] Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Adrenergic signaling in cardiomyocytes, Gap junction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy Epinephrine hydrochloride 💬 Epinephrine [4] 46, 70, 96, 97 💬
29 ADRB2 💬 [11] Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Adrenergic signaling in cardiomyocytes, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Chemical carcinogenesis - receptor activation Epinephrine bitartrate 💬 Epinephrine [4] 46, 70, 96, 97 💬
30 ADRB2 💬 [11] Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Adrenergic signaling in cardiomyocytes, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Chemical carcinogenesis - receptor activation Epinephrine 💬 Epinephrine [4] 46, 70, 96, 97 💬
31 ADRB2 💬 [11] Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Adrenergic signaling in cardiomyocytes, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Chemical carcinogenesis - receptor activation Epinephrine hydrochloride 💬 Epinephrine [4] 46, 70, 96, 97 💬
32 ADRB3 💬 [9] Calcium signaling pathway, cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Thermogenesis, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Chemical carcinogenesis - receptor activation Epinephrine 💬 Epinephrine [4] 46, 70, 96, 97 💬
33 ADRB3 💬 [9] Calcium signaling pathway, cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Thermogenesis, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Chemical carcinogenesis - receptor activation Epinephrine hydrochloride 💬 Epinephrine [4] 46, 70, 96, 97 💬
34 ADRB3 💬 [9] Calcium signaling pathway, cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Thermogenesis, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Chemical carcinogenesis - receptor activation Epinephrine bitartrate 💬 Epinephrine [4] 46, 70, 96, 97 💬
35 AGTR1 💬 [17] Calcium signaling pathway, cGMP-PKG signaling pathway, Phospholipase D signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Apelin signaling pathway, Renin-angiotensin system, Renin secretion, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, AGE-RAGE signaling pathway in diabetic complications, Cushing syndrome, Coronavirus disease, Pathways in cancer, Diabetic cardiomyopathy Losartan 💬 Losartan [20] 17, 19, 36, 46, 57, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 223, 299 💬
36 AGTR1 💬 [17] Calcium signaling pathway, cGMP-PKG signaling pathway, Phospholipase D signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Apelin signaling pathway, Renin-angiotensin system, Renin secretion, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, AGE-RAGE signaling pathway in diabetic complications, Cushing syndrome, Coronavirus disease, Pathways in cancer, Diabetic cardiomyopathy Losartan potassium 💬 Losartan [20] 17, 19, 36, 46, 57, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 223, 299 💬
37 ATP4A 💬 [3] Oxidative phosphorylation, Collecting duct acid secretion, Gastric acid secretion Omeprazole 💬 Omeprazole [18] 6, 8, 13, 21, 46, 51, 67, 85, 90, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬
38 ATP4A 💬 [3] Oxidative phosphorylation, Collecting duct acid secretion, Gastric acid secretion Omeprazole sodium 💬 Omeprazole [18] 6, 8, 13, 21, 46, 51, 67, 85, 90, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬
39 ATP4A 💬 [3] Oxidative phosphorylation, Collecting duct acid secretion, Gastric acid secretion Omeprazole magnesium 💬 Omeprazole [18] 6, 8, 13, 21, 46, 51, 67, 85, 90, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬
40 ATP4A 💬 [3] Oxidative phosphorylation, Collecting duct acid secretion, Gastric acid secretion Vonoprazan 💬 Vonoprazan [3] 63, 97, 98 💬
41 ATP4B 💬 [3] Oxidative phosphorylation, Collecting duct acid secretion, Gastric acid secretion Omeprazole sodium 💬 Omeprazole [18] 6, 8, 13, 21, 46, 51, 67, 85, 90, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬
42 ATP4B 💬 [3] Oxidative phosphorylation, Collecting duct acid secretion, Gastric acid secretion Vonoprazan 💬 Vonoprazan [3] 63, 97, 98 💬
43 ATP4B 💬 [3] Oxidative phosphorylation, Collecting duct acid secretion, Gastric acid secretion Omeprazole 💬 Omeprazole [18] 6, 8, 13, 21, 46, 51, 67, 85, 90, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬
44 ATP4B 💬 [3] Oxidative phosphorylation, Collecting duct acid secretion, Gastric acid secretion Omeprazole magnesium 💬 Omeprazole [18] 6, 8, 13, 21, 46, 51, 67, 85, 90, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬
45 AXL 💬 [1] Efferocytosis Cabozantinib 💬 Cabozantinib [9] 13, 34, 46, 49, 50, 51, 53, 96, 97 💬
46 AXL 💬 [1] Efferocytosis Cabozantinib s-malate 💬 Cabozantinib [9] 13, 34, 46, 49, 50, 51, 53, 96, 97 💬
47 CA2 💬 [6] Nitrogen metabolism, Proximal tubule bicarbonate reclamation, Collecting duct acid secretion, Gastric acid secretion, Pancreatic secretion, Bile secretion Topiramate 💬 Topiramate [6] 6, 97, 140, 144, 156, 193 💬
48 CA4 💬 [2] Nitrogen metabolism, Proximal tubule bicarbonate reclamation Topiramate 💬 Topiramate [6] 6, 97, 140, 144, 156, 193 💬
49 CACNA1C 💬 [34] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Circadian entrainment, Long-term potentiation, Retrograde endocannabinoid signaling, Glutamatergic synapse, Cholinergic synapse, Serotonergic synapse, GABAergic synapse, Dopaminergic synapse, Taste transduction, Insulin secretion, GnRH signaling pathway, Oxytocin signaling pathway, Renin secretion, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Type II diabetes mellitus, Cushing syndrome, Growth hormone synthesis, secretion and action, Alzheimer disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Chemical carcinogenesis - receptor activation, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Topiramate 💬 Topiramate [6] 6, 97, 140, 144, 156, 193 💬
50 CACNA1D 💬 [35] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Cellular senescence, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Tight junction, Circadian entrainment, Retrograde endocannabinoid signaling, Glutamatergic synapse, Cholinergic synapse, Serotonergic synapse, GABAergic synapse, Dopaminergic synapse, Insulin secretion, GnRH signaling pathway, Oxytocin signaling pathway, Renin secretion, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Type II diabetes mellitus, Cushing syndrome, Growth hormone synthesis, secretion and action, Carbohydrate digestion and absorption, Alzheimer disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Chemical carcinogenesis - receptor activation, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Topiramate 💬 Topiramate [6] 6, 97, 140, 144, 156, 193 💬
51 CACNA1F 💬 [27] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Cholinergic synapse, Serotonergic synapse, GABAergic synapse, Insulin secretion, GnRH signaling pathway, Oxytocin signaling pathway, Renin secretion, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Cushing syndrome, Growth hormone synthesis, secretion and action, Alzheimer disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Chemical carcinogenesis - receptor activation, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Topiramate 💬 Topiramate [6] 6, 97, 140, 144, 156, 193 💬
52 CACNA1S 💬 [27] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Cholinergic synapse, Serotonergic synapse, GABAergic synapse, Insulin secretion, GnRH signaling pathway, Oxytocin signaling pathway, Renin secretion, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Cushing syndrome, Growth hormone synthesis, secretion and action, Alzheimer disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Chemical carcinogenesis - receptor activation, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Topiramate 💬 Topiramate [6] 6, 97, 140, 144, 156, 193 💬
53 CD3D 💬 [11] Hematopoietic cell lineage, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Chagas disease, Measles, Human T-cell leukemia virus 1 infection, Epstein-Barr virus infection, Human immunodeficiency virus 1 infection, PD-L1 expression and PD-1 checkpoint pathway in cancer, Primary immunodeficiency Visilizumab 💬 Visilizumab [2] 96, 97 💬
54 CD3E 💬 [11] Hematopoietic cell lineage, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Chagas disease, Measles, Human T-cell leukemia virus 1 infection, Epstein-Barr virus infection, Human immunodeficiency virus 1 infection, PD-L1 expression and PD-1 checkpoint pathway in cancer, Primary immunodeficiency Visilizumab 💬 Visilizumab [2] 96, 97 💬
55 CD3G 💬 [10] Hematopoietic cell lineage, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Chagas disease, Measles, Human T-cell leukemia virus 1 infection, Epstein-Barr virus infection, Human immunodeficiency virus 1 infection, PD-L1 expression and PD-1 checkpoint pathway in cancer Visilizumab 💬 Visilizumab [2] 96, 97 💬
56 CD40 💬 [17] Cytokine-cytokine receptor interaction, NF-kappa B signaling pathway, Cell adhesion molecule (CAM) interaction, Toll-like receptor signaling pathway, Intestinal immune network for IgA production, Malaria, Toxoplasmosis, Human T-cell leukemia virus 1 infection, Epstein-Barr virus infection, Transcriptional misregulation in cancer, Asthma, Autoimmune thyroid disease, Systemic lupus erythematosus, Allograft rejection, Primary immunodeficiency, Viral myocarditis, Lipid and atherosclerosis Ravagalimab 💬 Ravagalimab [3] 46, 53, 97 💬
57 CD80 💬 [12] Virion - Adenovirus, Cell adhesion molecule (CAM) interaction, IgSF CAM signaling, Toll-like receptor signaling pathway, Intestinal immune network for IgA production, Type I diabetes mellitus, Autoimmune thyroid disease, Systemic lupus erythematosus, Rheumatoid arthritis, Allograft rejection, Graft-versus-host disease, Viral myocarditis Abatacept 💬 Abatacept [28] 2, 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 223, 271, 284, 285, 300 💬
58 CD86 💬 [14] Virion - Adenovirus, Cell adhesion molecule (CAM) interaction, IgSF CAM signaling, Toll-like receptor signaling pathway, Intestinal immune network for IgA production, Type I diabetes mellitus, Kaposi sarcoma-associated herpesvirus infection, Transcriptional misregulation in cancer, Autoimmune thyroid disease, Systemic lupus erythematosus, Rheumatoid arthritis, Allograft rejection, Graft-versus-host disease, Viral myocarditis Abatacept 💬 Abatacept [28] 2, 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 223, 271, 284, 285, 300 💬
59 CLCN2 💬 [1] Mineral absorption Lubiprostone 💬 Lubiprostone [5] 6, 13, 97, 290, 299 💬
60 CNR1 💬 [4] Rap1 signaling pathway, Neuroactive ligand-receptor interaction, Thermogenesis, Retrograde endocannabinoid signaling Cannabidiol 💬 Cannabidiol [20] 6, 8, 13, 19, 36, 46, 51, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271 💬
61 CNR1 💬 [4] Rap1 signaling pathway, Neuroactive ligand-receptor interaction, Thermogenesis, Retrograde endocannabinoid signaling Nabilone 💬 Nabilone [4] 6, 13, 97, 127 💬
62 CNR2 💬 [1] Neuroactive ligand-receptor interaction Cannabidiol 💬 Cannabidiol [20] 6, 8, 13, 19, 36, 46, 51, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271 💬
63 CNR2 💬 [1] Neuroactive ligand-receptor interaction Nabilone 💬 Nabilone [4] 6, 13, 97, 127 💬
64 CSF3R 💬 [5] Cytokine-cytokine receptor interaction, PI3K-Akt signaling pathway, JAK-STAT signaling pathway, Hematopoietic cell lineage, Pathways in cancer Lenograstim 💬 Lenograstim [8] 2, 13, 16, 18, 19, 57, 65, 97 💬
65 CTLA4 💬 [4] Cell adhesion molecule (CAM) interaction, T cell receptor signaling pathway, Autoimmune thyroid disease, Rheumatoid arthritis Ipilimumab 💬 Ipilimumab [9] 13, 46, 49, 50, 51, 53, 96, 97, 159 💬
66 CXCR1 💬 [6] Cytokine-cytokine receptor interaction, Viral protein interaction with cytokine and cytokine receptor, Chemokine signaling pathway, Phospholipase D signaling pathway, Endocytosis, Epithelial cell signaling in Helicobacter pylori infection Eltrekibart 💬 Eltrekibart [1] 97 💬
67 DHFR 💬 [3] One carbon pool by folate, Folate biosynthesis, Folate transport and metabolism Methotrexate 💬 Methotrexate [41] 11, 13, 14, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 54, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 223, 240, 256, 270, 271, 284, 285, 286, 326, 331 💬
68 DHFR 💬 [3] One carbon pool by folate, Folate biosynthesis, Folate transport and metabolism Methotrexate sodium 💬 Methotrexate [41] 11, 13, 14, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 54, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 223, 240, 256, 270, 271, 284, 285, 286, 326, 331 💬
69 DHFR2 💬 [3] One carbon pool by folate, Folate biosynthesis, Folate transport and metabolism Methotrexate sodium 💬 Methotrexate [41] 11, 13, 14, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 54, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 223, 240, 256, 270, 271, 284, 285, 286, 326, 331 💬
70 DHFR2 💬 [3] One carbon pool by folate, Folate biosynthesis, Folate transport and metabolism Methotrexate 💬 Methotrexate [41] 11, 13, 14, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 54, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 223, 240, 256, 270, 271, 284, 285, 286, 326, 331 💬
71 DHODH 💬 [1] Pyrimidine metabolism Vidofludimus 💬 Vidofludimus [5] 13, 46, 94, 96, 97 💬
72 DHODH 💬 [1] Pyrimidine metabolism Vidofludimus calcium 💬 Vidofludimus [5] 13, 46, 94, 96, 97 💬
73 DRD1 💬 [12] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Amphetamine addiction, Morphine addiction, Alcoholism Flupentixol dihydrochloride 💬 Flupentixol [1] 97 💬
74 DRD1 💬 [12] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Amphetamine addiction, Morphine addiction, Alcoholism Flupentixol decanoate 💬 Flupentixol [1] 97 💬
75 DRD1 💬 [12] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Amphetamine addiction, Morphine addiction, Alcoholism Flupentixol 💬 Flupentixol [1] 97 💬
76 DRD2 💬 [10] Rap1 signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Alcoholism Flupentixol dihydrochloride 💬 Flupentixol [1] 97 💬
77 DRD2 💬 [10] Rap1 signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Alcoholism Flupentixol decanoate 💬 Flupentixol [1] 97 💬
78 DRD2 💬 [10] Rap1 signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Alcoholism Flupentixol 💬 Flupentixol [1] 97 💬
79 F10 💬 [1] Complement and coagulation cascades Apixaban 💬 Apixaban [6] 48, 96, 97, 222, 223, 279 💬
80 FDPS 💬 [3] Terpenoid backbone biosynthesis, Influenza A, Human T-cell leukemia virus 1 infection Zoledronic acid hemipentahydrate 💬 Zoledronic acid [16] 5, 6, 13, 17, 46, 75, 77, 93, 95, 96, 97, 270, 274, 282, 299, 333 💬
81 FDPS 💬 [3] Terpenoid backbone biosynthesis, Influenza A, Human T-cell leukemia virus 1 infection Zoledronic acid 💬 Zoledronic acid [16] 5, 6, 13, 17, 46, 75, 77, 93, 95, 96, 97, 270, 274, 282, 299, 333 💬
82 FDPS 💬 [3] Terpenoid backbone biosynthesis, Influenza A, Human T-cell leukemia virus 1 infection Zoledronic acid 💬 Zoledronic acid [16] 5, 6, 13, 17, 46, 75, 77, 93, 95, 96, 97, 270, 274, 282, 299, 333 💬
83 FDPS 💬 [3] Terpenoid backbone biosynthesis, Influenza A, Human T-cell leukemia virus 1 infection Zoledronate disodium 💬 Zoledronic acid [16] 5, 6, 13, 17, 46, 75, 77, 93, 95, 96, 97, 270, 274, 282, 299, 333 💬
84 FDPS 💬 [3] Terpenoid backbone biosynthesis, Influenza A, Human T-cell leukemia virus 1 infection Zoledronate trisodium 💬 Zoledronic acid [16] 5, 6, 13, 17, 46, 75, 77, 93, 95, 96, 97, 270, 274, 282, 299, 333 💬
85 GABRA1 💬 [8] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Topiramate 💬 Topiramate [6] 6, 97, 140, 144, 156, 193 💬
86 GABRA1 💬 [8] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Midazolam maleate 💬 Midazolam [14] 2, 3, 6, 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬
87 GABRA1 💬 [8] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Midazolam hydrochloride 💬 Midazolam [14] 2, 3, 6, 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬
88 GABRA1 💬 [8] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Remimazolam besylate 💬 Remimazolam [3] 6, 22, 97 💬
89 GABRA1 💬 [8] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Propofol 💬 Propofol [10] 3, 6, 21, 22, 34, 46, 70, 97, 98, 296 💬
90 GABRA1 💬 [8] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Midazolam 💬 Midazolam [14] 2, 3, 6, 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬
91 GABRA1 💬 [8] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Remimazolam 💬 Remimazolam [3] 6, 22, 97 💬
92 GABRA2 💬 [8] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Propofol 💬 Propofol [10] 3, 6, 21, 22, 34, 46, 70, 97, 98, 296 💬
93 GABRA2 💬 [8] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Midazolam maleate 💬 Midazolam [14] 2, 3, 6, 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬
94 GABRA2 💬 [8] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Remimazolam 💬 Remimazolam [3] 6, 22, 97 💬
95 GABRA2 💬 [8] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Topiramate 💬 Topiramate [6] 6, 97, 140, 144, 156, 193 💬
96 GABRA2 💬 [8] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Midazolam hydrochloride 💬 Midazolam [14] 2, 3, 6, 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬
97 GABRA2 💬 [8] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Remimazolam besylate 💬 Remimazolam [3] 6, 22, 97 💬
98 GABRA2 💬 [8] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Midazolam 💬 Midazolam [14] 2, 3, 6, 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬
99 GABRA3 💬 [8] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Remimazolam 💬 Remimazolam [3] 6, 22, 97 💬
100 GABRA3 💬 [8] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Topiramate 💬 Topiramate [6] 6, 97, 140, 144, 156, 193 💬
101 GABRA3 💬 [8] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Midazolam hydrochloride 💬 Midazolam [14] 2, 3, 6, 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬
102 GABRA3 💬 [8] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Remimazolam besylate 💬 Remimazolam [3] 6, 22, 97 💬
103 GABRA3 💬 [8] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Midazolam maleate 💬 Midazolam [14] 2, 3, 6, 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬
104 GABRA3 💬 [8] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Propofol 💬 Propofol [10] 3, 6, 21, 22, 34, 46, 70, 97, 98, 296 💬
105 GABRA3 💬 [8] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Midazolam 💬 Midazolam [14] 2, 3, 6, 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬
106 GABRA4 💬 [8] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Remimazolam besylate 💬 Remimazolam [3] 6, 22, 97 💬
107 GABRA4 💬 [8] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Midazolam 💬 Midazolam [14] 2, 3, 6, 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬
108 GABRA4 💬 [8] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Topiramate 💬 Topiramate [6] 6, 97, 140, 144, 156, 193 💬
109 GABRA4 💬 [8] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Midazolam hydrochloride 💬 Midazolam [14] 2, 3, 6, 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬
110 GABRA4 💬 [8] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Remimazolam 💬 Remimazolam [3] 6, 22, 97 💬
111 GABRA4 💬 [8] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Midazolam maleate 💬 Midazolam [14] 2, 3, 6, 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬
112 GABRA4 💬 [8] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Propofol 💬 Propofol [10] 3, 6, 21, 22, 34, 46, 70, 97, 98, 296 💬
113 GABRA5 💬 [8] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Midazolam maleate 💬 Midazolam [14] 2, 3, 6, 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬
114 GABRA5 💬 [8] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Remimazolam besylate 💬 Remimazolam [3] 6, 22, 97 💬
115 GABRA5 💬 [8] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Remimazolam 💬 Remimazolam [3] 6, 22, 97 💬
116 GABRA5 💬 [8] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Topiramate 💬 Topiramate [6] 6, 97, 140, 144, 156, 193 💬
117 GABRA5 💬 [8] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Midazolam hydrochloride 💬 Midazolam [14] 2, 3, 6, 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬
118 GABRA5 💬 [8] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Midazolam 💬 Midazolam [14] 2, 3, 6, 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬
119 GABRA5 💬 [8] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Propofol 💬 Propofol [10] 3, 6, 21, 22, 34, 46, 70, 97, 98, 296 💬
120 GABRA6 💬 [8] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Remimazolam besylate 💬 Remimazolam [3] 6, 22, 97 💬
121 GABRA6 💬 [8] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Midazolam 💬 Midazolam [14] 2, 3, 6, 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬
122 GABRA6 💬 [8] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Midazolam maleate 💬 Midazolam [14] 2, 3, 6, 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬
123 GABRA6 💬 [8] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Topiramate 💬 Topiramate [6] 6, 97, 140, 144, 156, 193 💬
124 GABRA6 💬 [8] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Midazolam hydrochloride 💬 Midazolam [14] 2, 3, 6, 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬
125 GABRA6 💬 [8] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Propofol 💬 Propofol [10] 3, 6, 21, 22, 34, 46, 70, 97, 98, 296 💬
126 GABRA6 💬 [8] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Remimazolam 💬 Remimazolam [3] 6, 22, 97 💬
127 GABRB1 💬 [8] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, Serotonergic synapse, GABAergic synapse, Morphine addiction, Nicotine addiction Remimazolam 💬 Remimazolam [3] 6, 22, 97 💬
128 GABRB1 💬 [8] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, Serotonergic synapse, GABAergic synapse, Morphine addiction, Nicotine addiction Midazolam maleate 💬 Midazolam [14] 2, 3, 6, 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬
129 GABRB1 💬 [8] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, Serotonergic synapse, GABAergic synapse, Morphine addiction, Nicotine addiction Propofol 💬 Propofol [10] 3, 6, 21, 22, 34, 46, 70, 97, 98, 296 💬
130 GABRB1 💬 [8] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, Serotonergic synapse, GABAergic synapse, Morphine addiction, Nicotine addiction Topiramate 💬 Topiramate [6] 6, 97, 140, 144, 156, 193 💬
131 GABRB1 💬 [8] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, Serotonergic synapse, GABAergic synapse, Morphine addiction, Nicotine addiction Midazolam hydrochloride 💬 Midazolam [14] 2, 3, 6, 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬
132 GABRB1 💬 [8] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, Serotonergic synapse, GABAergic synapse, Morphine addiction, Nicotine addiction Midazolam 💬 Midazolam [14] 2, 3, 6, 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬
133 GABRB1 💬 [8] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, Serotonergic synapse, GABAergic synapse, Morphine addiction, Nicotine addiction Remimazolam besylate 💬 Remimazolam [3] 6, 22, 97 💬
134 GABRB2 💬 [8] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, Serotonergic synapse, GABAergic synapse, Morphine addiction, Nicotine addiction Propofol 💬 Propofol [10] 3, 6, 21, 22, 34, 46, 70, 97, 98, 296 💬
135 GABRB2 💬 [8] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, Serotonergic synapse, GABAergic synapse, Morphine addiction, Nicotine addiction Midazolam 💬 Midazolam [14] 2, 3, 6, 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬
136 GABRB2 💬 [8] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, Serotonergic synapse, GABAergic synapse, Morphine addiction, Nicotine addiction Midazolam hydrochloride 💬 Midazolam [14] 2, 3, 6, 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬
137 GABRB2 💬 [8] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, Serotonergic synapse, GABAergic synapse, Morphine addiction, Nicotine addiction Remimazolam 💬 Remimazolam [3] 6, 22, 97 💬
138 GABRB2 💬 [8] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, Serotonergic synapse, GABAergic synapse, Morphine addiction, Nicotine addiction Topiramate 💬 Topiramate [6] 6, 97, 140, 144, 156, 193 💬
139 GABRB2 💬 [8] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, Serotonergic synapse, GABAergic synapse, Morphine addiction, Nicotine addiction Midazolam maleate 💬 Midazolam [14] 2, 3, 6, 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬
140 GABRB2 💬 [8] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, Serotonergic synapse, GABAergic synapse, Morphine addiction, Nicotine addiction Remimazolam besylate 💬 Remimazolam [3] 6, 22, 97 💬
141 GABRB3 💬 [8] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, Serotonergic synapse, GABAergic synapse, Morphine addiction, Nicotine addiction Midazolam hydrochloride 💬 Midazolam [14] 2, 3, 6, 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬
142 GABRB3 💬 [8] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, Serotonergic synapse, GABAergic synapse, Morphine addiction, Nicotine addiction Topiramate 💬 Topiramate [6] 6, 97, 140, 144, 156, 193 💬
143 GABRB3 💬 [8] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, Serotonergic synapse, GABAergic synapse, Morphine addiction, Nicotine addiction Remimazolam besylate 💬 Remimazolam [3] 6, 22, 97 💬
144 GABRB3 💬 [8] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, Serotonergic synapse, GABAergic synapse, Morphine addiction, Nicotine addiction Midazolam maleate 💬 Midazolam [14] 2, 3, 6, 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬
145 GABRB3 💬 [8] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, Serotonergic synapse, GABAergic synapse, Morphine addiction, Nicotine addiction Remimazolam 💬 Remimazolam [3] 6, 22, 97 💬
146 GABRB3 💬 [8] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, Serotonergic synapse, GABAergic synapse, Morphine addiction, Nicotine addiction Midazolam 💬 Midazolam [14] 2, 3, 6, 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬
147 GABRB3 💬 [8] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, Serotonergic synapse, GABAergic synapse, Morphine addiction, Nicotine addiction Propofol 💬 Propofol [10] 3, 6, 21, 22, 34, 46, 70, 97, 98, 296 💬
148 GABRD 💬 [7] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Remimazolam besylate 💬 Remimazolam [3] 6, 22, 97 💬
149 GABRD 💬 [7] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Midazolam maleate 💬 Midazolam [14] 2, 3, 6, 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬
150 GABRD 💬 [7] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Midazolam hydrochloride 💬 Midazolam [14] 2, 3, 6, 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬
151 GABRD 💬 [7] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Remimazolam 💬 Remimazolam [3] 6, 22, 97 💬
152 GABRD 💬 [7] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Propofol 💬 Propofol [10] 3, 6, 21, 22, 34, 46, 70, 97, 98, 296 💬
153 GABRD 💬 [7] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Midazolam 💬 Midazolam [14] 2, 3, 6, 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬
154 GABRD 💬 [7] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Topiramate 💬 Topiramate [6] 6, 97, 140, 144, 156, 193 💬
155 GABRE 💬 [7] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Midazolam maleate 💬 Midazolam [14] 2, 3, 6, 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬
156 GABRE 💬 [7] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Midazolam hydrochloride 💬 Midazolam [14] 2, 3, 6, 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬
157 GABRE 💬 [7] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Topiramate 💬 Topiramate [6] 6, 97, 140, 144, 156, 193 💬
158 GABRE 💬 [7] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Remimazolam besylate 💬 Remimazolam [3] 6, 22, 97 💬
159 GABRE 💬 [7] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Propofol 💬 Propofol [10] 3, 6, 21, 22, 34, 46, 70, 97, 98, 296 💬
160 GABRE 💬 [7] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Remimazolam 💬 Remimazolam [3] 6, 22, 97 💬
161 GABRE 💬 [7] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Midazolam 💬 Midazolam [14] 2, 3, 6, 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬
162 GABRG1 💬 [7] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Remimazolam besylate 💬 Remimazolam [3] 6, 22, 97 💬
163 GABRG1 💬 [7] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Remimazolam 💬 Remimazolam [3] 6, 22, 97 💬
164 GABRG1 💬 [7] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Midazolam hydrochloride 💬 Midazolam [14] 2, 3, 6, 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬
165 GABRG1 💬 [7] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Propofol 💬 Propofol [10] 3, 6, 21, 22, 34, 46, 70, 97, 98, 296 💬
166 GABRG1 💬 [7] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Midazolam 💬 Midazolam [14] 2, 3, 6, 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬
167 GABRG1 💬 [7] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Midazolam maleate 💬 Midazolam [14] 2, 3, 6, 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬
168 GABRG1 💬 [7] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Topiramate 💬 Topiramate [6] 6, 97, 140, 144, 156, 193 💬
169 GABRG2 💬 [7] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Midazolam maleate 💬 Midazolam [14] 2, 3, 6, 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬
170 GABRG2 💬 [7] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Topiramate 💬 Topiramate [6] 6, 97, 140, 144, 156, 193 💬
171 GABRG2 💬 [7] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Remimazolam 💬 Remimazolam [3] 6, 22, 97 💬
172 GABRG2 💬 [7] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Midazolam 💬 Midazolam [14] 2, 3, 6, 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬
173 GABRG2 💬 [7] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Propofol 💬 Propofol [10] 3, 6, 21, 22, 34, 46, 70, 97, 98, 296 💬
174 GABRG2 💬 [7] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Remimazolam besylate 💬 Remimazolam [3] 6, 22, 97 💬
175 GABRG2 💬 [7] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Midazolam hydrochloride 💬 Midazolam [14] 2, 3, 6, 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬
176 GABRG3 💬 [7] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Midazolam maleate 💬 Midazolam [14] 2, 3, 6, 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬
177 GABRG3 💬 [7] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Propofol 💬 Propofol [10] 3, 6, 21, 22, 34, 46, 70, 97, 98, 296 💬
178 GABRG3 💬 [7] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Topiramate 💬 Topiramate [6] 6, 97, 140, 144, 156, 193 💬
179 GABRG3 💬 [7] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Remimazolam besylate 💬 Remimazolam [3] 6, 22, 97 💬
180 GABRG3 💬 [7] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Remimazolam 💬 Remimazolam [3] 6, 22, 97 💬
181 GABRG3 💬 [7] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Midazolam hydrochloride 💬 Midazolam [14] 2, 3, 6, 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬
182 GABRG3 💬 [7] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Midazolam 💬 Midazolam [14] 2, 3, 6, 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬
183 GABRP 💬 [7] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Midazolam hydrochloride 💬 Midazolam [14] 2, 3, 6, 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬
184 GABRP 💬 [7] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Topiramate 💬 Topiramate [6] 6, 97, 140, 144, 156, 193 💬
185 GABRP 💬 [7] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Midazolam maleate 💬 Midazolam [14] 2, 3, 6, 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬
186 GABRP 💬 [7] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Remimazolam 💬 Remimazolam [3] 6, 22, 97 💬
187 GABRP 💬 [7] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Midazolam 💬 Midazolam [14] 2, 3, 6, 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬
188 GABRP 💬 [7] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Propofol 💬 Propofol [10] 3, 6, 21, 22, 34, 46, 70, 97, 98, 296 💬
189 GABRP 💬 [7] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Remimazolam besylate 💬 Remimazolam [3] 6, 22, 97 💬
190 GABRQ 💬 [7] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Remimazolam besylate 💬 Remimazolam [3] 6, 22, 97 💬
191 GABRQ 💬 [7] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Topiramate 💬 Topiramate [6] 6, 97, 140, 144, 156, 193 💬
192 GABRQ 💬 [7] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Midazolam 💬 Midazolam [14] 2, 3, 6, 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬
193 GABRQ 💬 [7] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Remimazolam 💬 Remimazolam [3] 6, 22, 97 💬
194 GABRQ 💬 [7] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Propofol 💬 Propofol [10] 3, 6, 21, 22, 34, 46, 70, 97, 98, 296 💬
195 GABRQ 💬 [7] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Midazolam maleate 💬 Midazolam [14] 2, 3, 6, 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬
196 GABRQ 💬 [7] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Midazolam hydrochloride 💬 Midazolam [14] 2, 3, 6, 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬
197 GIPR 💬 [3] cAMP signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling Tirzepatide 💬 Tirzepatide [6] 67, 96, 97, 193, 233, 265 💬
198 GLP1R 💬 [4] cAMP signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Insulin secretion Tirzepatide 💬 Tirzepatide [6] 67, 96, 97, 193, 233, 265 💬
199 GRIA1 💬 [15] cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Retrograde endocannabinoid signaling, Glutamatergic synapse, Dopaminergic synapse, Long-term depression, Amyotrophic lateral sclerosis, Huntington disease, Spinocerebellar ataxia, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Nicotine addiction Topiramate 💬 Topiramate [6] 6, 97, 140, 144, 156, 193 💬
200 GRIA2 💬 [16] cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Retrograde endocannabinoid signaling, Glutamatergic synapse, Dopaminergic synapse, Long-term depression, Amyotrophic lateral sclerosis, Huntington disease, Spinocerebellar ataxia, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction Topiramate 💬 Topiramate [6] 6, 97, 140, 144, 156, 193 💬
201 GRIA3 💬 [14] cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Retrograde endocannabinoid signaling, Glutamatergic synapse, Dopaminergic synapse, Long-term depression, Huntington disease, Spinocerebellar ataxia, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Nicotine addiction, Transcriptional misregulation in cancer Topiramate 💬 Topiramate [6] 6, 97, 140, 144, 156, 193 💬
202 GRIA4 💬 [11] cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Retrograde endocannabinoid signaling, Glutamatergic synapse, Dopaminergic synapse, Huntington disease, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Nicotine addiction Topiramate 💬 Topiramate [6] 6, 97, 140, 144, 156, 193 💬
203 GRIK1 💬 [3] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Glutamatergic synapse Topiramate 💬 Topiramate [6] 6, 97, 140, 144, 156, 193 💬
204 GRIK2 💬 [3] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Glutamatergic synapse Topiramate 💬 Topiramate [6] 6, 97, 140, 144, 156, 193 💬
205 GRIK3 💬 [3] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Glutamatergic synapse Topiramate 💬 Topiramate [6] 6, 97, 140, 144, 156, 193 💬
206 GRIK4 💬 [3] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Glutamatergic synapse Topiramate 💬 Topiramate [6] 6, 97, 140, 144, 156, 193 💬
207 GRIK5 💬 [3] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Glutamatergic synapse Topiramate 💬 Topiramate [6] 6, 97, 140, 144, 156, 193 💬
208 GRIN1 💬 [19] Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Huntington disease, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism Dextromethorphan hydrobromide 💬 Dextromethorphan [10] 2, 6, 8, 13, 21, 46, 85, 96, 97, 156 💬
209 GRIN1 💬 [19] Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Huntington disease, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism Dextromethorphan polistirex 💬 Dextromethorphan [10] 2, 6, 8, 13, 21, 46, 85, 96, 97, 156 💬
210 GRIN1 💬 [19] Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Huntington disease, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism Dextromethorphan 💬 Dextromethorphan [10] 2, 6, 8, 13, 21, 46, 85, 96, 97, 156 💬
211 GRIN1 💬 [19] Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Huntington disease, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism Esketamine hydrochloride 💬 Esketamine [7] 2, 4, 6, 70, 96, 97, 156 💬
212 GRIN1 💬 [19] Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Huntington disease, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism Esketamine 💬 Esketamine [7] 2, 4, 6, 70, 96, 97, 156 💬
213 GRIN2A 💬 [20] Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Dopaminergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism, Systemic lupus erythematosus Dextromethorphan hydrobromide 💬 Dextromethorphan [10] 2, 6, 8, 13, 21, 46, 85, 96, 97, 156 💬
214 GRIN2A 💬 [20] Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Dopaminergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism, Systemic lupus erythematosus Dextromethorphan polistirex 💬 Dextromethorphan [10] 2, 6, 8, 13, 21, 46, 85, 96, 97, 156 💬
215 GRIN2A 💬 [20] Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Dopaminergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism, Systemic lupus erythematosus Esketamine hydrochloride 💬 Esketamine [7] 2, 4, 6, 70, 96, 97, 156 💬
216 GRIN2A 💬 [20] Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Dopaminergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism, Systemic lupus erythematosus Esketamine 💬 Esketamine [7] 2, 4, 6, 70, 96, 97, 156 💬
217 GRIN2A 💬 [20] Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Dopaminergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism, Systemic lupus erythematosus Dextromethorphan 💬 Dextromethorphan [10] 2, 6, 8, 13, 21, 46, 85, 96, 97, 156 💬
218 GRIN2B 💬 [21] Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Dopaminergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Huntington disease, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism, Systemic lupus erythematosus Dextromethorphan polistirex 💬 Dextromethorphan [10] 2, 6, 8, 13, 21, 46, 85, 96, 97, 156 💬
219 GRIN2B 💬 [21] Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Dopaminergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Huntington disease, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism, Systemic lupus erythematosus Esketamine hydrochloride 💬 Esketamine [7] 2, 4, 6, 70, 96, 97, 156 💬
220 GRIN2B 💬 [21] Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Dopaminergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Huntington disease, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism, Systemic lupus erythematosus Esketamine 💬 Esketamine [7] 2, 4, 6, 70, 96, 97, 156 💬
221 GRIN2B 💬 [21] Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Dopaminergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Huntington disease, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism, Systemic lupus erythematosus Dextromethorphan hydrobromide 💬 Dextromethorphan [10] 2, 6, 8, 13, 21, 46, 85, 96, 97, 156 💬
222 GRIN2B 💬 [21] Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Dopaminergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Huntington disease, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism, Systemic lupus erythematosus Dextromethorphan 💬 Dextromethorphan [10] 2, 6, 8, 13, 21, 46, 85, 96, 97, 156 💬
223 GRIN2C 💬 [16] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism Dextromethorphan polistirex 💬 Dextromethorphan [10] 2, 6, 8, 13, 21, 46, 85, 96, 97, 156 💬
224 GRIN2C 💬 [16] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism Esketamine 💬 Esketamine [7] 2, 4, 6, 70, 96, 97, 156 💬
225 GRIN2C 💬 [16] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism Dextromethorphan 💬 Dextromethorphan [10] 2, 6, 8, 13, 21, 46, 85, 96, 97, 156 💬
226 GRIN2C 💬 [16] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism Dextromethorphan hydrobromide 💬 Dextromethorphan [10] 2, 6, 8, 13, 21, 46, 85, 96, 97, 156 💬
227 GRIN2C 💬 [16] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism Esketamine hydrochloride 💬 Esketamine [7] 2, 4, 6, 70, 96, 97, 156 💬
228 GRIN2D 💬 [16] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism Esketamine hydrochloride 💬 Esketamine [7] 2, 4, 6, 70, 96, 97, 156 💬
229 GRIN2D 💬 [16] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism Esketamine 💬 Esketamine [7] 2, 4, 6, 70, 96, 97, 156 💬
230 GRIN2D 💬 [16] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism Dextromethorphan 💬 Dextromethorphan [10] 2, 6, 8, 13, 21, 46, 85, 96, 97, 156 💬
231 GRIN2D 💬 [16] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism Dextromethorphan polistirex 💬 Dextromethorphan [10] 2, 6, 8, 13, 21, 46, 85, 96, 97, 156 💬
232 GRIN2D 💬 [16] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism Dextromethorphan hydrobromide 💬 Dextromethorphan [10] 2, 6, 8, 13, 21, 46, 85, 96, 97, 156 💬
233 GUCY2C 💬 [2] Purine metabolism, Hormone signaling Linaclotide 💬 Linaclotide [3] 6, 97, 299 💬
234 GUCY2C 💬 [2] Purine metabolism, Hormone signaling Linaclotide acetate 💬 Linaclotide [3] 6, 97, 299 💬
235 HDAC1 💬 [18] ATP-dependent chromatin remodeling, Polycomb repressive complex, Cell cycle, Longevity regulating pathway - multiple species, Notch signaling pathway, TGF-beta signaling pathway, Neutrophil extracellular trap formation, Thyroid hormone signaling pathway, Huntington disease, Amphetamine addiction, Alcoholism, Human papillomavirus infection, Epstein-Barr virus infection, Pathways in cancer, Transcriptional misregulation in cancer, Viral carcinogenesis, MicroRNAs in cancer, Chronic myeloid leukemia Vorinostat 💬 Vorinostat [5] 65, 75, 96, 97, 156 💬
236 HDAC10 💬 [3] Neutrophil extracellular trap formation, Alcoholism, Viral carcinogenesis Vorinostat 💬 Vorinostat [5] 65, 75, 96, 97, 156 💬
237 HDAC11 💬 [3] Neutrophil extracellular trap formation, Alcoholism, Viral carcinogenesis Vorinostat 💬 Vorinostat [5] 65, 75, 96, 97, 156 💬
238 HDAC2 💬 [18] ATP-dependent chromatin remodeling, Polycomb repressive complex, Cell cycle, Longevity regulating pathway - multiple species, Notch signaling pathway, TGF-beta signaling pathway, Neutrophil extracellular trap formation, Thyroid hormone signaling pathway, Huntington disease, Amphetamine addiction, Alcoholism, Human papillomavirus infection, Epstein-Barr virus infection, Pathways in cancer, Transcriptional misregulation in cancer, Viral carcinogenesis, MicroRNAs in cancer, Chronic myeloid leukemia Vorinostat 💬 Vorinostat [5] 65, 75, 96, 97, 156 💬
239 HDAC3 💬 [4] Neutrophil extracellular trap formation, Thyroid hormone signaling pathway, Alcoholism, Viral carcinogenesis Vorinostat 💬 Vorinostat [5] 65, 75, 96, 97, 156 💬
240 HDAC4 💬 [5] Apelin signaling pathway, Neutrophil extracellular trap formation, Alcoholism, Viral carcinogenesis, MicroRNAs in cancer Vorinostat 💬 Vorinostat [5] 65, 75, 96, 97, 156 💬
241 HDAC5 💬 [5] Apelin signaling pathway, Neutrophil extracellular trap formation, Alcoholism, Viral carcinogenesis, MicroRNAs in cancer Vorinostat 💬 Vorinostat [5] 65, 75, 96, 97, 156 💬
242 HDAC6 💬 [4] Neutrophil extracellular trap formation, Amyotrophic lateral sclerosis, Alcoholism, Viral carcinogenesis Vorinostat 💬 Vorinostat [5] 65, 75, 96, 97, 156 💬
243 HDAC7 💬 [3] Neutrophil extracellular trap formation, Alcoholism, Viral carcinogenesis Vorinostat 💬 Vorinostat [5] 65, 75, 96, 97, 156 💬
244 HDAC8 💬 [4] Cell cycle, Neutrophil extracellular trap formation, Alcoholism, Viral carcinogenesis Vorinostat 💬 Vorinostat [5] 65, 75, 96, 97, 156 💬
245 HDAC9 💬 [3] Neutrophil extracellular trap formation, Alcoholism, Viral carcinogenesis Vorinostat 💬 Vorinostat [5] 65, 75, 96, 97, 156 💬
246 HMGCR 💬 [3] Terpenoid backbone biosynthesis, AMPK signaling pathway, Bile secretion Atorvastatin 💬 Atorvastatin [21] 13, 22, 46, 49, 51, 58, 63, 67, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 297, 299 💬
247 HMGCR 💬 [3] Terpenoid backbone biosynthesis, AMPK signaling pathway, Bile secretion Rosuvastatin 💬 Rosuvastatin [16] 6, 18, 46, 49, 51, 56, 57, 62, 65, 67, 79, 94, 96, 97, 271, 299 💬
248 HMGCR 💬 [3] Terpenoid backbone biosynthesis, AMPK signaling pathway, Bile secretion Rosuvastatin calcium 💬 Rosuvastatin [16] 6, 18, 46, 49, 51, 56, 57, 62, 65, 67, 79, 94, 96, 97, 271, 299 💬
249 HMGCR 💬 [3] Terpenoid backbone biosynthesis, AMPK signaling pathway, Bile secretion Atorvastatin calcium 💬 Atorvastatin [21] 13, 22, 46, 49, 51, 58, 63, 67, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 297, 299 💬
250 HPRT1 💬 [2] Purine metabolism, Drug metabolism - other enzymes Mercaptopurine 💬 Mercaptopurine [4] 65, 96, 97, 164 💬
251 HPRT1 💬 [2] Purine metabolism, Drug metabolism - other enzymes Mercaptopurine 💬 Mercaptopurine [4] 65, 96, 97, 164 💬
252 HRH1 💬 [4] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Inflammatory mediator regulation of TRP channels Rupatadine 💬 Rupatadine [2] 46, 97 💬
253 HRH1 💬 [4] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Inflammatory mediator regulation of TRP channels Rupatadine fumarate 💬 Rupatadine [2] 46, 97 💬
254 HRH1 💬 [4] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Inflammatory mediator regulation of TRP channels Desloratadine 💬 Desloratadine [3] 13, 46, 97 💬
255 HTR2A 💬 [6] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Gap junction, Serotonergic synapse, Inflammatory mediator regulation of TRP channels Mirtazapine 💬 Mirtazapine [4] 6, 85, 97, 156 💬
256 HTR2B 💬 [6] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Gap junction, Serotonergic synapse, Inflammatory mediator regulation of TRP channels Mirtazapine 💬 Mirtazapine [4] 6, 85, 97, 156 💬
257 HTR2C 💬 [6] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Gap junction, Serotonergic synapse, Inflammatory mediator regulation of TRP channels Mirtazapine 💬 Mirtazapine [4] 6, 85, 97, 156 💬
258 HTR3A 💬 [3] Neuroactive ligand signaling, Serotonergic synapse, Taste transduction Ondansetron 💬 Ondansetron [5] 6, 97, 98, 107, 231 💬
259 HTR3A 💬 [3] Neuroactive ligand signaling, Serotonergic synapse, Taste transduction Ramosetron 💬 Ramosetron [1] 97 💬
260 HTR3A 💬 [3] Neuroactive ligand signaling, Serotonergic synapse, Taste transduction Mirtazapine 💬 Mirtazapine [4] 6, 85, 97, 156 💬
261 HTR3A 💬 [3] Neuroactive ligand signaling, Serotonergic synapse, Taste transduction Ondansetron hydrochloride hydrate 💬 Ondansetron [5] 6, 97, 98, 107, 231 💬
262 HTR3A 💬 [3] Neuroactive ligand signaling, Serotonergic synapse, Taste transduction Ramosetron hydrochloride 💬 Ramosetron [1] 97 💬
263 HTR3B 💬 [3] Neuroactive ligand signaling, Serotonergic synapse, Taste transduction Ramosetron hydrochloride 💬 Ramosetron [1] 97 💬
264 HTR3B 💬 [3] Neuroactive ligand signaling, Serotonergic synapse, Taste transduction Mirtazapine 💬 Mirtazapine [4] 6, 85, 97, 156 💬
265 HTR3B 💬 [3] Neuroactive ligand signaling, Serotonergic synapse, Taste transduction Ondansetron hydrochloride hydrate 💬 Ondansetron [5] 6, 97, 98, 107, 231 💬
266 HTR3B 💬 [3] Neuroactive ligand signaling, Serotonergic synapse, Taste transduction Ondansetron 💬 Ondansetron [5] 6, 97, 98, 107, 231 💬
267 HTR3B 💬 [3] Neuroactive ligand signaling, Serotonergic synapse, Taste transduction Ramosetron 💬 Ramosetron [1] 97 💬
268 HTR3C 💬 [3] Neuroactive ligand signaling, Serotonergic synapse, Taste transduction Ramosetron hydrochloride 💬 Ramosetron [1] 97 💬
269 HTR3C 💬 [3] Neuroactive ligand signaling, Serotonergic synapse, Taste transduction Ondansetron 💬 Ondansetron [5] 6, 97, 98, 107, 231 💬
270 HTR3C 💬 [3] Neuroactive ligand signaling, Serotonergic synapse, Taste transduction Ramosetron 💬 Ramosetron [1] 97 💬
271 HTR3C 💬 [3] Neuroactive ligand signaling, Serotonergic synapse, Taste transduction Mirtazapine 💬 Mirtazapine [4] 6, 85, 97, 156 💬
272 HTR3C 💬 [3] Neuroactive ligand signaling, Serotonergic synapse, Taste transduction Ondansetron hydrochloride hydrate 💬 Ondansetron [5] 6, 97, 98, 107, 231 💬
273 HTR3D 💬 [3] Neuroactive ligand signaling, Serotonergic synapse, Taste transduction Ramosetron 💬 Ramosetron [1] 97 💬
274 HTR3D 💬 [3] Neuroactive ligand signaling, Serotonergic synapse, Taste transduction Mirtazapine 💬 Mirtazapine [4] 6, 85, 97, 156 💬
275 HTR3D 💬 [3] Neuroactive ligand signaling, Serotonergic synapse, Taste transduction Ondansetron hydrochloride hydrate 💬 Ondansetron [5] 6, 97, 98, 107, 231 💬
276 HTR3D 💬 [3] Neuroactive ligand signaling, Serotonergic synapse, Taste transduction Ondansetron 💬 Ondansetron [5] 6, 97, 98, 107, 231 💬
277 HTR3D 💬 [3] Neuroactive ligand signaling, Serotonergic synapse, Taste transduction Ramosetron hydrochloride 💬 Ramosetron [1] 97 💬
278 HTR3E 💬 [3] Neuroactive ligand signaling, Serotonergic synapse, Taste transduction Ondansetron 💬 Ondansetron [5] 6, 97, 98, 107, 231 💬
279 HTR3E 💬 [3] Neuroactive ligand signaling, Serotonergic synapse, Taste transduction Mirtazapine 💬 Mirtazapine [4] 6, 85, 97, 156 💬
280 HTR3E 💬 [3] Neuroactive ligand signaling, Serotonergic synapse, Taste transduction Ondansetron hydrochloride hydrate 💬 Ondansetron [5] 6, 97, 98, 107, 231 💬
281 HTR3E 💬 [3] Neuroactive ligand signaling, Serotonergic synapse, Taste transduction Ramosetron hydrochloride 💬 Ramosetron [1] 97 💬
282 HTR3E 💬 [3] Neuroactive ligand signaling, Serotonergic synapse, Taste transduction Ramosetron 💬 Ramosetron [1] 97 💬
283 ICAM1 💬 [19] NF-kappa B signaling pathway, Cell adhesion molecule (CAM) interaction, IgSF CAM signaling, Integrin signaling, Natural killer cell mediated cytotoxicity, TNF signaling pathway, Leukocyte transendothelial migration, AGE-RAGE signaling pathway in diabetic complications, African trypanosomiasis, Malaria, Staphylococcus aureus infection, Influenza A, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Epstein-Barr virus infection, Rheumatoid arthritis, Viral myocarditis, Lipid and atherosclerosis, Fluid shear stress and atherosclerosis Alicaforsen sodium 💬 Alicaforsen [2] 96, 97 💬
284 IFNAR1 💬 [18] Cytokine-cytokine receptor interaction, PI3K-Akt signaling pathway, Necroptosis, Osteoclast differentiation, Toll-like receptor signaling pathway, NOD-like receptor signaling pathway, JAK-STAT signaling pathway, Natural killer cell mediated cytotoxicity, Hepatitis C, Hepatitis B, Measles, Influenza A, Human papillomavirus infection, Kaposi sarcoma-associated herpesvirus infection, Herpes simplex virus 1 infection, Epstein-Barr virus infection, Coronavirus disease, Pathways in cancer Interferon beta-1a 💬 Interferon beta-1a [5] 13, 14, 26, 96, 97 💬
285 IFNAR2 💬 [17] Cytokine-cytokine receptor interaction, PI3K-Akt signaling pathway, Necroptosis, Osteoclast differentiation, Toll-like receptor signaling pathway, NOD-like receptor signaling pathway, JAK-STAT signaling pathway, Natural killer cell mediated cytotoxicity, Hepatitis C, Measles, Influenza A, Human papillomavirus infection, Kaposi sarcoma-associated herpesvirus infection, Herpes simplex virus 1 infection, Epstein-Barr virus infection, Coronavirus disease, Pathways in cancer Interferon beta-1a 💬 Interferon beta-1a [5] 13, 14, 26, 96, 97 💬
286 IL12A 💬 [25] Cytokine-cytokine receptor interaction, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, C-type lectin receptor signaling pathway, JAK-STAT signaling pathway, Th1 and Th2 cell differentiation, Alcoholic liver disease, Type I diabetes mellitus, Pertussis, Legionellosis, Leishmaniasis, Chagas disease, African trypanosomiasis, Malaria, Toxoplasmosis, Amoebiasis, Tuberculosis, Measles, Influenza A, Herpes simplex virus 1 infection, Coronavirus disease, Pathways in cancer, Inflammatory bowel disease, Allograft rejection, Lipid and atherosclerosis Ustekinumab 💬 Ustekinumab [17] 37, 40, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
287 IL12B 💬 [25] Cytokine-cytokine receptor interaction, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, C-type lectin receptor signaling pathway, JAK-STAT signaling pathway, Th1 and Th2 cell differentiation, Alcoholic liver disease, Type I diabetes mellitus, Pertussis, Legionellosis, Leishmaniasis, Chagas disease, African trypanosomiasis, Toxoplasmosis, Amoebiasis, Tuberculosis, Measles, Influenza A, Herpes simplex virus 1 infection, Coronavirus disease, Pathways in cancer, Proteoglycans in cancer, Inflammatory bowel disease, Allograft rejection, Lipid and atherosclerosis Ustekinumab 💬 Ustekinumab [17] 37, 40, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
288 IL13 💬 [8] Cytokine-cytokine receptor interaction, JAK-STAT signaling pathway, IL-17 signaling pathway, Th1 and Th2 cell differentiation, Fc epsilon RI signaling pathway, Pathways in cancer, Asthma, Inflammatory bowel disease Anrukinzumab 💬 Anrukinzumab [1] 97 💬
289 IL13 💬 [8] Cytokine-cytokine receptor interaction, JAK-STAT signaling pathway, IL-17 signaling pathway, Th1 and Th2 cell differentiation, Fc epsilon RI signaling pathway, Pathways in cancer, Asthma, Inflammatory bowel disease Tralokinumab 💬 Tralokinumab [2] 85, 97 💬
290 IL17A 💬 [6] Cytokine-cytokine receptor interaction, IL-17 signaling pathway, Th17 cell differentiation, Alcoholic liver disease, Inflammatory bowel disease, Rheumatoid arthritis Bimekizumab 💬 Bimekizumab [5] 37, 46, 97, 107, 271 💬
291 IL17F 💬 [4] Cytokine-cytokine receptor interaction, IL-17 signaling pathway, Th17 cell differentiation, Inflammatory bowel disease Bimekizumab 💬 Bimekizumab [5] 37, 46, 97, 107, 271 💬
292 IL1A 💬 [21] MAPK signaling pathway, Cytokine-cytokine receptor interaction, Necroptosis, Cellular senescence, Osteoclast differentiation, Hematopoietic cell lineage, Non-alcoholic fatty liver disease, AGE-RAGE signaling pathway in diabetic complications, Type I diabetes mellitus, Alzheimer disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Pertussis, Leishmaniasis, Tuberculosis, Measles, Influenza A, Inflammatory bowel disease, Rheumatoid arthritis, Graft-versus-host disease, Fluid shear stress and atherosclerosis Lutikizumab 💬 Lutikizumab [3] 46, 96, 97 💬
293 IL1B 💬 [43] MAPK signaling pathway, Cytokine-cytokine receptor interaction, NF-kappa B signaling pathway, Necroptosis, Osteoclast differentiation, Toll-like receptor signaling pathway, NOD-like receptor signaling pathway, Cytosolic DNA-sensing pathway, C-type lectin receptor signaling pathway, Hematopoietic cell lineage, IL-17 signaling pathway, Th17 cell differentiation, TNF signaling pathway, Inflammatory mediator regulation of TRP channels, Non-alcoholic fatty liver disease, AGE-RAGE signaling pathway in diabetic complications, Alcoholic liver disease, Type I diabetes mellitus, Alzheimer disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Shigellosis, Salmonella infection, Pertussis, Legionellosis, Yersinia infection, Leishmaniasis, Chagas disease, African trypanosomiasis, Malaria, Amoebiasis, Tuberculosis, Measles, Human cytomegalovirus infection, Influenza A, Herpes simplex virus 1 infection, Coronavirus disease, Inflammatory bowel disease, Rheumatoid arthritis, Graft-versus-host disease, Lipid and atherosclerosis, Fluid shear stress and atherosclerosis Lutikizumab 💬 Lutikizumab [3] 46, 96, 97 💬
294 IL1R1 💬 [13] MAPK signaling pathway, Cytokine-cytokine receptor interaction, NF-kappa B signaling pathway, Osteoclast differentiation, Hematopoietic cell lineage, Th17 cell differentiation, Inflammatory mediator regulation of TRP channels, Pathogenic Escherichia coli infection, Shigellosis, Amoebiasis, Human cytomegalovirus infection, Human T-cell leukemia virus 1 infection, Fluid shear stress and atherosclerosis Anakinra 💬 Anakinra [22] 2, 13, 15, 19, 28, 37, 41, 46, 49, 50, 54, 56, 57, 84, 86, 97, 106, 107, 149, 153, 266, 299 💬
295 IL1R2 💬 [7] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, Amoebiasis, Human T-cell leukemia virus 1 infection, Transcriptional misregulation in cancer, Prostate cancer, Fluid shear stress and atherosclerosis Anakinra 💬 Anakinra [22] 2, 13, 15, 19, 28, 37, 41, 46, 49, 50, 54, 56, 57, 84, 86, 97, 106, 107, 149, 153, 266, 299 💬
296 IL1RL2 💬 [1] Cytokine-cytokine receptor interaction Spesolimab 💬 Spesolimab [5] 37, 96, 97, 160, 269 💬
297 IL22 💬 [4] Cytokine-cytokine receptor interaction, JAK-STAT signaling pathway, Th17 cell differentiation, Inflammatory bowel disease Efmarodocokin alfa 💬 Efmarodocokin alfa [2] 96, 97 💬
298 IL23A 💬 [9] Cytokine-cytokine receptor interaction, C-type lectin receptor signaling pathway, JAK-STAT signaling pathway, Th17 cell differentiation, Pertussis, Tuberculosis, Pathways in cancer, Inflammatory bowel disease, Rheumatoid arthritis Risankizumab 💬 Risankizumab [4] 37, 96, 97, 271 💬
299 IL23A 💬 [9] Cytokine-cytokine receptor interaction, C-type lectin receptor signaling pathway, JAK-STAT signaling pathway, Th17 cell differentiation, Pertussis, Tuberculosis, Pathways in cancer, Inflammatory bowel disease, Rheumatoid arthritis Mirikizumab 💬 Mirikizumab [3] 37, 96, 97 💬
300 IL23A 💬 [9] Cytokine-cytokine receptor interaction, C-type lectin receptor signaling pathway, JAK-STAT signaling pathway, Th17 cell differentiation, Pertussis, Tuberculosis, Pathways in cancer, Inflammatory bowel disease, Rheumatoid arthritis Brazikumab 💬 Brazikumab [2] 96, 97 💬
301 IL23A 💬 [9] Cytokine-cytokine receptor interaction, C-type lectin receptor signaling pathway, JAK-STAT signaling pathway, Th17 cell differentiation, Pertussis, Tuberculosis, Pathways in cancer, Inflammatory bowel disease, Rheumatoid arthritis Ustekinumab 💬 Ustekinumab [17] 37, 40, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
302 IL23A 💬 [9] Cytokine-cytokine receptor interaction, C-type lectin receptor signaling pathway, JAK-STAT signaling pathway, Th17 cell differentiation, Pertussis, Tuberculosis, Pathways in cancer, Inflammatory bowel disease, Rheumatoid arthritis Guselkumab 💬 Guselkumab [7] 37, 41, 51, 96, 97, 161, 269 💬
303 IL23R 💬 [5] Cytokine-cytokine receptor interaction, JAK-STAT signaling pathway, Th17 cell differentiation, Pathways in cancer, Inflammatory bowel disease Icotrokinra 💬 Icotrokinra [2] 96, 97 💬
304 IL2RA 💬 [11] Cytokine-cytokine receptor interaction, Viral protein interaction with cytokine and cytokine receptor, Endocytosis, PI3K-Akt signaling pathway, JAK-STAT signaling pathway, Hematopoietic cell lineage, Th1 and Th2 cell differentiation, Th17 cell differentiation, Measles, Human T-cell leukemia virus 1 infection, Pathways in cancer Aldesleukin 💬 Aldesleukin [5] 2, 49, 65, 96, 97 💬
305 IL2RA 💬 [11] Cytokine-cytokine receptor interaction, Viral protein interaction with cytokine and cytokine receptor, Endocytosis, PI3K-Akt signaling pathway, JAK-STAT signaling pathway, Hematopoietic cell lineage, Th1 and Th2 cell differentiation, Th17 cell differentiation, Measles, Human T-cell leukemia virus 1 infection, Pathways in cancer Basiliximab 💬 Basiliximab [5] 2, 50, 97, 222, 228 💬
306 IL2RA 💬 [11] Cytokine-cytokine receptor interaction, Viral protein interaction with cytokine and cytokine receptor, Endocytosis, PI3K-Akt signaling pathway, JAK-STAT signaling pathway, Hematopoietic cell lineage, Th1 and Th2 cell differentiation, Th17 cell differentiation, Measles, Human T-cell leukemia virus 1 infection, Pathways in cancer Daclizumab 💬 Daclizumab [10] 13, 26, 56, 60, 63, 65, 97, 107, 283, 284 💬
307 IL2RB 💬 [11] Cytokine-cytokine receptor interaction, Viral protein interaction with cytokine and cytokine receptor, Endocytosis, PI3K-Akt signaling pathway, JAK-STAT signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Measles, Human T-cell leukemia virus 1 infection, Pathways in cancer, Transcriptional misregulation in cancer Aldesleukin 💬 Aldesleukin [5] 2, 49, 65, 96, 97 💬
308 IL2RG 💬 [12] Cytokine-cytokine receptor interaction, Viral protein interaction with cytokine and cytokine receptor, Endocytosis, PI3K-Akt signaling pathway, JAK-STAT signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Measles, Human T-cell leukemia virus 1 infection, Pathways in cancer, Inflammatory bowel disease, Primary immunodeficiency Aldesleukin 💬 Aldesleukin [5] 2, 49, 65, 96, 97 💬
309 IL4R 💬 [8] Cytokine-cytokine receptor interaction, PI3K-Akt signaling pathway, JAK-STAT signaling pathway, Hematopoietic cell lineage, Th1 and Th2 cell differentiation, Th17 cell differentiation, Pathways in cancer, Inflammatory bowel disease Dupilumab 💬 Dupilumab [8] 51, 97, 98, 160, 162, 222, 300, 306 💬
310 IL7R 💬 [7] Cytokine-cytokine receptor interaction, FoxO signaling pathway, PI3K-Akt signaling pathway, JAK-STAT signaling pathway, Hematopoietic cell lineage, Pathways in cancer, Primary immunodeficiency Lusvertikimab 💬 Lusvertikimab [1] 97 💬
311 ITGA4 💬 [17] PI3K-Akt signaling pathway, Focal adhesion, ECM-receptor interaction, Cell adhesion molecule (CAM) interaction, IgSF CAM signaling, Integrin signaling, Hematopoietic cell lineage, Leukocyte transendothelial migration, Intestinal immune network for IgA production, Regulation of actin cytoskeleton, Cytoskeleton in muscle cells, Yersinia infection, Leishmaniasis, Human papillomavirus infection, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Carotegrast methyl 💬 Carotegrast methyl [1] 97 💬
312 ITGA4 💬 [17] PI3K-Akt signaling pathway, Focal adhesion, ECM-receptor interaction, Cell adhesion molecule (CAM) interaction, IgSF CAM signaling, Integrin signaling, Hematopoietic cell lineage, Leukocyte transendothelial migration, Intestinal immune network for IgA production, Regulation of actin cytoskeleton, Cytoskeleton in muscle cells, Yersinia infection, Leishmaniasis, Human papillomavirus infection, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Abrilumab 💬 Abrilumab [2] 96, 97 💬
313 ITGA4 💬 [17] PI3K-Akt signaling pathway, Focal adhesion, ECM-receptor interaction, Cell adhesion molecule (CAM) interaction, IgSF CAM signaling, Integrin signaling, Hematopoietic cell lineage, Leukocyte transendothelial migration, Intestinal immune network for IgA production, Regulation of actin cytoskeleton, Cytoskeleton in muscle cells, Yersinia infection, Leishmaniasis, Human papillomavirus infection, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Vedolizumab 💬 Vedolizumab [3] 94, 96, 97 💬
314 ITGB1 💬 [29] Virion - Rotavirus, Rap1 signaling pathway, Phagocytosis, PI3K-Akt signaling pathway, Axon guidance, Focal adhesion, ECM-receptor interaction, Cell adhesion molecule (CAM) interaction, IgSF CAM signaling, Integrin signaling, Tight junction, Platelet activation, Leukocyte transendothelial migration, Regulation of actin cytoskeleton, Cytoskeleton in muscle cells, Bacterial invasion of epithelial cells, Pathogenic Escherichia coli infection, Shigellosis, Pertussis, Yersinia infection, Leishmaniasis, Toxoplasmosis, Human papillomavirus infection, Pathways in cancer, Proteoglycans in cancer, Small cell lung cancer, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Carotegrast methyl 💬 Carotegrast methyl [1] 97 💬
315 ITGB7 💬 [13] PI3K-Akt signaling pathway, Focal adhesion, ECM-receptor interaction, Cell adhesion molecule (CAM) interaction, Integrin signaling, Intestinal immune network for IgA production, Regulation of actin cytoskeleton, Cytoskeleton in muscle cells, Human papillomavirus infection, Transcriptional misregulation in cancer, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Vedolizumab 💬 Vedolizumab [3] 94, 96, 97 💬
316 ITGB7 💬 [13] PI3K-Akt signaling pathway, Focal adhesion, ECM-receptor interaction, Cell adhesion molecule (CAM) interaction, Integrin signaling, Intestinal immune network for IgA production, Regulation of actin cytoskeleton, Cytoskeleton in muscle cells, Human papillomavirus infection, Transcriptional misregulation in cancer, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Abrilumab 💬 Abrilumab [2] 96, 97 💬
317 ITGB7 💬 [13] PI3K-Akt signaling pathway, Focal adhesion, ECM-receptor interaction, Cell adhesion molecule (CAM) interaction, Integrin signaling, Intestinal immune network for IgA production, Regulation of actin cytoskeleton, Cytoskeleton in muscle cells, Human papillomavirus infection, Transcriptional misregulation in cancer, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Carotegrast methyl 💬 Carotegrast methyl [1] 97 💬
318 ITGB7 💬 [13] PI3K-Akt signaling pathway, Focal adhesion, ECM-receptor interaction, Cell adhesion molecule (CAM) interaction, Integrin signaling, Intestinal immune network for IgA production, Regulation of actin cytoskeleton, Cytoskeleton in muscle cells, Human papillomavirus infection, Transcriptional misregulation in cancer, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Etrolizumab 💬 Etrolizumab [2] 96, 97 💬
319 JAK1 💬 [27] PI3K-Akt signaling pathway, Necroptosis, Osteoclast differentiation, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, NOD-like receptor signaling pathway, JAK-STAT signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Leishmaniasis, Toxoplasmosis, Tuberculosis, Hepatitis C, Hepatitis B, Measles, Human cytomegalovirus infection, Influenza A, Human papillomavirus infection, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Herpes simplex virus 1 infection, Epstein-Barr virus infection, Coronavirus disease, Pathways in cancer, Viral carcinogenesis, Pancreatic cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer Filgotinib 💬 Filgotinib [10] 46, 53, 56, 96, 97, 107, 222, 271, 300, 331 💬
320 JAK1 💬 [27] PI3K-Akt signaling pathway, Necroptosis, Osteoclast differentiation, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, NOD-like receptor signaling pathway, JAK-STAT signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Leishmaniasis, Toxoplasmosis, Tuberculosis, Hepatitis C, Hepatitis B, Measles, Human cytomegalovirus infection, Influenza A, Human papillomavirus infection, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Herpes simplex virus 1 infection, Epstein-Barr virus infection, Coronavirus disease, Pathways in cancer, Viral carcinogenesis, Pancreatic cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer Upadacitinib hydrate 💬 Upadacitinib [12] 40, 41, 46, 49, 53, 55, 63, 96, 97, 98, 107, 271 💬
321 JAK1 💬 [27] PI3K-Akt signaling pathway, Necroptosis, Osteoclast differentiation, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, NOD-like receptor signaling pathway, JAK-STAT signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Leishmaniasis, Toxoplasmosis, Tuberculosis, Hepatitis C, Hepatitis B, Measles, Human cytomegalovirus infection, Influenza A, Human papillomavirus infection, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Herpes simplex virus 1 infection, Epstein-Barr virus infection, Coronavirus disease, Pathways in cancer, Viral carcinogenesis, Pancreatic cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer Tofacitinib citrate 💬 Tofacitinib [23] 2, 11, 35, 38, 39, 40, 44, 46, 49, 50, 51, 53, 56, 65, 66, 84, 96, 97, 107, 110, 162, 271, 300 💬
322 JAK1 💬 [27] PI3K-Akt signaling pathway, Necroptosis, Osteoclast differentiation, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, NOD-like receptor signaling pathway, JAK-STAT signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Leishmaniasis, Toxoplasmosis, Tuberculosis, Hepatitis C, Hepatitis B, Measles, Human cytomegalovirus infection, Influenza A, Human papillomavirus infection, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Herpes simplex virus 1 infection, Epstein-Barr virus infection, Coronavirus disease, Pathways in cancer, Viral carcinogenesis, Pancreatic cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer Upadacitinib 💬 Upadacitinib [12] 40, 41, 46, 49, 53, 55, 63, 96, 97, 98, 107, 271 💬
323 JAK1 💬 [27] PI3K-Akt signaling pathway, Necroptosis, Osteoclast differentiation, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, NOD-like receptor signaling pathway, JAK-STAT signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Leishmaniasis, Toxoplasmosis, Tuberculosis, Hepatitis C, Hepatitis B, Measles, Human cytomegalovirus infection, Influenza A, Human papillomavirus infection, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Herpes simplex virus 1 infection, Epstein-Barr virus infection, Coronavirus disease, Pathways in cancer, Viral carcinogenesis, Pancreatic cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer Upadacitinib tartrate 💬 Upadacitinib [12] 40, 41, 46, 49, 53, 55, 63, 96, 97, 98, 107, 271 💬
324 JAK1 💬 [27] PI3K-Akt signaling pathway, Necroptosis, Osteoclast differentiation, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, NOD-like receptor signaling pathway, JAK-STAT signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Leishmaniasis, Toxoplasmosis, Tuberculosis, Hepatitis C, Hepatitis B, Measles, Human cytomegalovirus infection, Influenza A, Human papillomavirus infection, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Herpes simplex virus 1 infection, Epstein-Barr virus infection, Coronavirus disease, Pathways in cancer, Viral carcinogenesis, Pancreatic cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer Filgotinib maleate 💬 Filgotinib [10] 46, 53, 56, 96, 97, 107, 222, 271, 300, 331 💬
325 JAK1 💬 [27] PI3K-Akt signaling pathway, Necroptosis, Osteoclast differentiation, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, NOD-like receptor signaling pathway, JAK-STAT signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Leishmaniasis, Toxoplasmosis, Tuberculosis, Hepatitis C, Hepatitis B, Measles, Human cytomegalovirus infection, Influenza A, Human papillomavirus infection, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Herpes simplex virus 1 infection, Epstein-Barr virus infection, Coronavirus disease, Pathways in cancer, Viral carcinogenesis, Pancreatic cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer Itacitinib adipate 💬 Itacitinib [4] 46, 51, 97, 228 💬
326 JAK1 💬 [27] PI3K-Akt signaling pathway, Necroptosis, Osteoclast differentiation, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, NOD-like receptor signaling pathway, JAK-STAT signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Leishmaniasis, Toxoplasmosis, Tuberculosis, Hepatitis C, Hepatitis B, Measles, Human cytomegalovirus infection, Influenza A, Human papillomavirus infection, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Herpes simplex virus 1 infection, Epstein-Barr virus infection, Coronavirus disease, Pathways in cancer, Viral carcinogenesis, Pancreatic cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer Itacitinib 💬 Itacitinib [4] 46, 51, 97, 228 💬
327 JAK1 💬 [27] PI3K-Akt signaling pathway, Necroptosis, Osteoclast differentiation, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, NOD-like receptor signaling pathway, JAK-STAT signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Leishmaniasis, Toxoplasmosis, Tuberculosis, Hepatitis C, Hepatitis B, Measles, Human cytomegalovirus infection, Influenza A, Human papillomavirus infection, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Herpes simplex virus 1 infection, Epstein-Barr virus infection, Coronavirus disease, Pathways in cancer, Viral carcinogenesis, Pancreatic cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer Tofacitinib 💬 Tofacitinib [23] 2, 11, 35, 38, 39, 40, 44, 46, 49, 50, 51, 53, 56, 65, 66, 84, 96, 97, 107, 110, 162, 271, 300 💬
328 JAK1 💬 [27] PI3K-Akt signaling pathway, Necroptosis, Osteoclast differentiation, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, NOD-like receptor signaling pathway, JAK-STAT signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Leishmaniasis, Toxoplasmosis, Tuberculosis, Hepatitis C, Hepatitis B, Measles, Human cytomegalovirus infection, Influenza A, Human papillomavirus infection, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Herpes simplex virus 1 infection, Epstein-Barr virus infection, Coronavirus disease, Pathways in cancer, Viral carcinogenesis, Pancreatic cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer Brepocitinib 💬 Brepocitinib [5] 49, 50, 84, 96, 97 💬
329 JAK2 💬 [25] Chemokine signaling pathway, Hormone signaling, Efferocytosis, PI3K-Akt signaling pathway, Necroptosis, Signaling pathways regulating pluripotency of stem cells, JAK-STAT signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Cholinergic synapse, Prolactin signaling pathway, Adipocytokine signaling pathway, AGE-RAGE signaling pathway in diabetic complications, Growth hormone synthesis, secretion and action, Leishmaniasis, Toxoplasmosis, Tuberculosis, Hepatitis B, Influenza A, Kaposi sarcoma-associated herpesvirus infection, Herpes simplex virus 1 infection, Pathways in cancer, Chemical carcinogenesis - receptor activation, PD-L1 expression and PD-1 checkpoint pathway in cancer, Lipid and atherosclerosis Tofacitinib citrate 💬 Tofacitinib [23] 2, 11, 35, 38, 39, 40, 44, 46, 49, 50, 51, 53, 56, 65, 66, 84, 96, 97, 107, 110, 162, 271, 300 💬
330 JAK2 💬 [25] Chemokine signaling pathway, Hormone signaling, Efferocytosis, PI3K-Akt signaling pathway, Necroptosis, Signaling pathways regulating pluripotency of stem cells, JAK-STAT signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Cholinergic synapse, Prolactin signaling pathway, Adipocytokine signaling pathway, AGE-RAGE signaling pathway in diabetic complications, Growth hormone synthesis, secretion and action, Leishmaniasis, Toxoplasmosis, Tuberculosis, Hepatitis B, Influenza A, Kaposi sarcoma-associated herpesvirus infection, Herpes simplex virus 1 infection, Pathways in cancer, Chemical carcinogenesis - receptor activation, PD-L1 expression and PD-1 checkpoint pathway in cancer, Lipid and atherosclerosis Filgotinib maleate 💬 Filgotinib [10] 46, 53, 56, 96, 97, 107, 222, 271, 300, 331 💬
331 JAK2 💬 [25] Chemokine signaling pathway, Hormone signaling, Efferocytosis, PI3K-Akt signaling pathway, Necroptosis, Signaling pathways regulating pluripotency of stem cells, JAK-STAT signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Cholinergic synapse, Prolactin signaling pathway, Adipocytokine signaling pathway, AGE-RAGE signaling pathway in diabetic complications, Growth hormone synthesis, secretion and action, Leishmaniasis, Toxoplasmosis, Tuberculosis, Hepatitis B, Influenza A, Kaposi sarcoma-associated herpesvirus infection, Herpes simplex virus 1 infection, Pathways in cancer, Chemical carcinogenesis - receptor activation, PD-L1 expression and PD-1 checkpoint pathway in cancer, Lipid and atherosclerosis Tofacitinib 💬 Tofacitinib [23] 2, 11, 35, 38, 39, 40, 44, 46, 49, 50, 51, 53, 56, 65, 66, 84, 96, 97, 107, 110, 162, 271, 300 💬
332 JAK3 💬 [15] Chemokine signaling pathway, PI3K-Akt signaling pathway, Necroptosis, Signaling pathways regulating pluripotency of stem cells, JAK-STAT signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Hepatitis B, Measles, Human T-cell leukemia virus 1 infection, Epstein-Barr virus infection, Pathways in cancer, Viral carcinogenesis, Non-small cell lung cancer, Primary immunodeficiency Tofacitinib citrate 💬 Tofacitinib [23] 2, 11, 35, 38, 39, 40, 44, 46, 49, 50, 51, 53, 56, 65, 66, 84, 96, 97, 107, 110, 162, 271, 300 💬
333 JAK3 💬 [15] Chemokine signaling pathway, PI3K-Akt signaling pathway, Necroptosis, Signaling pathways regulating pluripotency of stem cells, JAK-STAT signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Hepatitis B, Measles, Human T-cell leukemia virus 1 infection, Epstein-Barr virus infection, Pathways in cancer, Viral carcinogenesis, Non-small cell lung cancer, Primary immunodeficiency Tofacitinib 💬 Tofacitinib [23] 2, 11, 35, 38, 39, 40, 44, 46, 49, 50, 51, 53, 56, 65, 66, 84, 96, 97, 107, 110, 162, 271, 300 💬
334 JAK3 💬 [15] Chemokine signaling pathway, PI3K-Akt signaling pathway, Necroptosis, Signaling pathways regulating pluripotency of stem cells, JAK-STAT signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Hepatitis B, Measles, Human T-cell leukemia virus 1 infection, Epstein-Barr virus infection, Pathways in cancer, Viral carcinogenesis, Non-small cell lung cancer, Primary immunodeficiency Filgotinib maleate 💬 Filgotinib [10] 46, 53, 56, 96, 97, 107, 222, 271, 300, 331 💬
335 JAK3 💬 [15] Chemokine signaling pathway, PI3K-Akt signaling pathway, Necroptosis, Signaling pathways regulating pluripotency of stem cells, JAK-STAT signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Hepatitis B, Measles, Human T-cell leukemia virus 1 infection, Epstein-Barr virus infection, Pathways in cancer, Viral carcinogenesis, Non-small cell lung cancer, Primary immunodeficiency Ritlecitinib tosylate 💬 Ritlecitinib [3] 46, 96, 97 💬
336 KDR 💬 [12] MAPK signaling pathway, Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, PI3K-Akt signaling pathway, VEGF signaling pathway, Focal adhesion, IgSF CAM signaling, Integrin signaling, Cadherin signaling, Proteoglycans in cancer, Fluid shear stress and atherosclerosis Cabozantinib s-malate 💬 Cabozantinib [9] 13, 34, 46, 49, 50, 51, 53, 96, 97 💬
337 KDR 💬 [12] MAPK signaling pathway, Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, PI3K-Akt signaling pathway, VEGF signaling pathway, Focal adhesion, IgSF CAM signaling, Integrin signaling, Cadherin signaling, Proteoglycans in cancer, Fluid shear stress and atherosclerosis Cabozantinib 💬 Cabozantinib [9] 13, 34, 46, 49, 50, 51, 53, 96, 97 💬
338 LIPC 💬 [2] Glycerolipid metabolism, Cholesterol metabolism Dextran sulfate sodium 💬 Dextran [5] 2, 62, 79, 96, 97 💬
339 LPL 💬 [4] Glycerolipid metabolism, PPAR signaling pathway, Cholesterol metabolism, Alzheimer disease Dextran sulfate sodium 💬 Dextran [5] 2, 62, 79, 96, 97 💬
340 LTB 💬 [3] Cytokine-cytokine receptor interaction, NF-kappa B signaling pathway, Rheumatoid arthritis Baminercept 💬 Baminercept [4] 13, 46, 53, 97 💬
341 MAOA 💬 [13] Glycine, serine and threonine metabolism, Arginine and proline metabolism, Histidine metabolism, Tyrosine metabolism, Phenylalanine metabolism, Tryptophan metabolism, Drug metabolism - cytochrome P450, Serotonergic synapse, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Amphetamine addiction, Alcoholism Phentermine hydrochloride 💬 Phentermine [1] 97 💬
342 MAOA 💬 [13] Glycine, serine and threonine metabolism, Arginine and proline metabolism, Histidine metabolism, Tyrosine metabolism, Phenylalanine metabolism, Tryptophan metabolism, Drug metabolism - cytochrome P450, Serotonergic synapse, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Amphetamine addiction, Alcoholism Phentermine 💬 Phentermine [1] 97 💬
343 MAOB 💬 [13] Glycine, serine and threonine metabolism, Arginine and proline metabolism, Histidine metabolism, Tyrosine metabolism, Phenylalanine metabolism, Tryptophan metabolism, Drug metabolism - cytochrome P450, Serotonergic synapse, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Amphetamine addiction, Alcoholism Phentermine hydrochloride 💬 Phentermine [1] 97 💬
344 MAOB 💬 [13] Glycine, serine and threonine metabolism, Arginine and proline metabolism, Histidine metabolism, Tyrosine metabolism, Phenylalanine metabolism, Tryptophan metabolism, Drug metabolism - cytochrome P450, Serotonergic synapse, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Amphetamine addiction, Alcoholism Phentermine 💬 Phentermine [1] 97 💬
345 MET 💬 [24] MAPK signaling pathway, Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, PI3K-Akt signaling pathway, Axon guidance, Focal adhesion, Integrin signaling, Cadherin signaling, Adherens junction, Bacterial invasion of epithelial cells, Epithelial cell signaling in Helicobacter pylori infection, Malaria, Pathways in cancer, Transcriptional misregulation in cancer, Proteoglycans in cancer, MicroRNAs in cancer, Chemical carcinogenesis - reactive oxygen species, Renal cell carcinoma, Melanoma, Non-small cell lung cancer, Hepatocellular carcinoma, Gastric cancer, Central carbon metabolism in cancer Cabozantinib 💬 Cabozantinib [9] 13, 34, 46, 49, 50, 51, 53, 96, 97 💬
346 MET 💬 [24] MAPK signaling pathway, Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, PI3K-Akt signaling pathway, Axon guidance, Focal adhesion, Integrin signaling, Cadherin signaling, Adherens junction, Bacterial invasion of epithelial cells, Epithelial cell signaling in Helicobacter pylori infection, Malaria, Pathways in cancer, Transcriptional misregulation in cancer, Proteoglycans in cancer, MicroRNAs in cancer, Chemical carcinogenesis - reactive oxygen species, Renal cell carcinoma, Melanoma, Non-small cell lung cancer, Hepatocellular carcinoma, Gastric cancer, Central carbon metabolism in cancer Cabozantinib s-malate 💬 Cabozantinib [9] 13, 34, 46, 49, 50, 51, 53, 96, 97 💬
347 MMP9 💬 [16] Phagocytosis, IL-17 signaling pathway, TNF signaling pathway, Leukocyte transendothelial migration, Estrogen signaling pathway, Relaxin signaling pathway, Hepatitis B, Pathways in cancer, Transcriptional misregulation in cancer, Proteoglycans in cancer, MicroRNAs in cancer, Prostate cancer, Bladder cancer, Diabetic cardiomyopathy, Lipid and atherosclerosis, Fluid shear stress and atherosclerosis Andecaliximab 💬 Andecaliximab [5] 46, 96, 97, 272, 299 💬
348 MS4A1 💬 [1] Hematopoietic cell lineage Rituximab 💬 Rituximab [54] 11, 13, 14, 19, 26, 34, 35, 36, 40, 41, 42, 43, 44, 45, 46, 48, 49, 50, 51, 52, 53, 55, 56, 60, 61, 62, 63, 64, 65, 66, 83, 84, 85, 86, 88, 93, 94, 96, 97, 162, 172, 222, 223, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331 💬
349 MTNR1A 💬 [2] Neuroactive ligand-receptor interaction, Circadian entrainment Melatonin 💬 Melatonin [18] 2, 6, 8, 13, 37, 46, 49, 72, 78, 86, 90, 96, 97, 145, 149, 159, 202, 265 💬
350 MTNR1B 💬 [2] Neuroactive ligand-receptor interaction, Circadian entrainment Melatonin 💬 Melatonin [18] 2, 6, 8, 13, 37, 46, 49, 72, 78, 86, 90, 96, 97, 145, 149, 159, 202, 265 💬
351 MTOR 💬 [52] ErbB signaling pathway, HIF-1 signaling pathway, Phospholipase D signaling pathway, Autophagy - other, Autophagy - animal, Lysosome biogenesis, mTOR signaling pathway, PI3K-Akt signaling pathway, AMPK signaling pathway, Integrated stress response (ISR) signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Cellular senescence, Apelin signaling pathway, Integrin signaling, Neutrophil extracellular trap formation, JAK-STAT signaling pathway, Th17 cell differentiation, Thermogenesis, Insulin signaling pathway, Thyroid hormone signaling pathway, Adipocytokine signaling pathway, Type II diabetes mellitus, Insulin resistance, Growth hormone synthesis, secretion and action, Alzheimer disease, Amyotrophic lateral sclerosis, Huntington disease, Spinocerebellar ataxia, Pathways of neurodegeneration - multiple diseases, Shigellosis, Human cytomegalovirus infection, Human papillomavirus infection, Kaposi sarcoma-associated herpesvirus infection, Herpes simplex virus 1 infection, Human immunodeficiency virus 1 infection, Pathways in cancer, Proteoglycans in cancer, MicroRNAs in cancer, Chemical carcinogenesis - receptor activation, Colorectal cancer, Pancreatic cancer, Glioma, Prostate cancer, Acute myeloid leukemia, Breast cancer, Hepatocellular carcinoma, Gastric cancer, Central carbon metabolism in cancer, Choline metabolism in cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer, Diabetic cardiomyopathy Sirolimus 💬 Sirolimus [46] 6, 13, 15, 17, 19, 21, 34, 35, 36, 46, 48, 49, 51, 54, 57, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 97, 98, 111, 127, 137, 157, 158, 192, 222, 223, 227, 277, 278, 279, 280, 281, 283, 285, 300, 331 💬
352 NCBP1 💬 [4] Nucleocytoplasmic transport, mRNA surveillance pathway, Spliceosome, Amyotrophic lateral sclerosis Obefazimod 💬 Obefazimod [2] 96, 97 💬
353 NCBP2 💬 [3] Nucleocytoplasmic transport, mRNA surveillance pathway, Spliceosome Obefazimod 💬 Obefazimod [2] 96, 97 💬
354 NCBP2L 💬 [3] Nucleocytoplasmic transport, mRNA surveillance pathway, Spliceosome Obefazimod 💬 Obefazimod [2] 96, 97 💬
355 NQO1 💬 [5] Ubiquinone and other terpenoid-quinone biosynthesis, Pathways in cancer, Chemical carcinogenesis - reactive oxygen species, Hepatocellular carcinoma, Fluid shear stress and atherosclerosis Warfarin 💬 Warfarin [15] 6, 8, 13, 19, 46, 48, 49, 66, 85, 86, 88, 91, 96, 97, 222 💬
356 NQO1 💬 [5] Ubiquinone and other terpenoid-quinone biosynthesis, Pathways in cancer, Chemical carcinogenesis - reactive oxygen species, Hepatocellular carcinoma, Fluid shear stress and atherosclerosis Warfarin potassium 💬 Warfarin [15] 6, 8, 13, 19, 46, 48, 49, 66, 85, 86, 88, 91, 96, 97, 222 💬
357 NQO1 💬 [5] Ubiquinone and other terpenoid-quinone biosynthesis, Pathways in cancer, Chemical carcinogenesis - reactive oxygen species, Hepatocellular carcinoma, Fluid shear stress and atherosclerosis Warfarin sodium 💬 Warfarin [15] 6, 8, 13, 19, 46, 48, 49, 66, 85, 86, 88, 91, 96, 97, 222 💬
358 NR1H4 💬 [1] Bile secretion Ursodiol 💬 Ursodeoxycholic acid [10] 6, 46, 67, 84, 93, 94, 95, 96, 97, 296 💬
359 NR3C1 💬 [1] Neuroactive ligand-receptor interaction Dexamethasone sodium phosphate 💬 Dexamethasone [29] 13, 14, 16, 19, 28, 35, 46, 53, 63, 64, 65, 70, 71, 74, 75, 81, 84, 90, 96, 97, 162, 222, 223, 235, 257, 283, 296, 299, 331 💬
360 NR3C1 💬 [1] Neuroactive ligand-receptor interaction Vamorolone 💬 Vamorolone [2] 97, 113 💬
361 NR3C1 💬 [1] Neuroactive ligand-receptor interaction Beclomethasone dipropionate monohydrate 💬 Beclomethasone dipropionate [2] 97, 98 💬
362 NR3C1 💬 [1] Neuroactive ligand-receptor interaction Hydrocortisone succinate 💬 Hydrocortisone succinate [3] 81, 83, 97 💬
363 NR3C1 💬 [1] Neuroactive ligand-receptor interaction Dexamethasone phosphate 💬 Dexamethasone [29] 13, 14, 16, 19, 28, 35, 46, 53, 63, 64, 65, 70, 71, 74, 75, 81, 84, 90, 96, 97, 162, 222, 223, 235, 257, 283, 296, 299, 331 💬
364 NR3C1 💬 [1] Neuroactive ligand-receptor interaction Methylprednisolone acetate 💬 Methylprednisolone [51] 2, 6, 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 95, 96, 97, 111, 127, 145, 162, 164, 211, 222, 223, 224, 271, 283, 284, 285, 296, 300 💬
365 NR3C1 💬 [1] Neuroactive ligand-receptor interaction Budesonide 💬 Budesonide [10] 66, 93, 94, 95, 96, 97, 98, 223, 228, 299 💬
366 NR3C1 💬 [1] Neuroactive ligand-receptor interaction Beclomethasone dipropionate 💬 Beclomethasone dipropionate [2] 97, 98 💬
367 NR3C1 💬 [1] Neuroactive ligand-receptor interaction Methylprednisolone 💬 Methylprednisolone [51] 2, 6, 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 95, 96, 97, 111, 127, 145, 162, 164, 211, 222, 223, 224, 271, 283, 284, 285, 296, 300 💬
368 NR3C1 💬 [1] Neuroactive ligand-receptor interaction Hydrocortisone 💬 Hydrocortisone [10] 6, 41, 46, 53, 75, 78, 81, 83, 97, 299 💬
369 NR3C1 💬 [1] Neuroactive ligand-receptor interaction Dexamethasone 💬 Dexamethasone [29] 13, 14, 16, 19, 28, 35, 46, 53, 63, 64, 65, 70, 71, 74, 75, 81, 84, 90, 96, 97, 162, 222, 223, 235, 257, 283, 296, 299, 331 💬
370 NR3C1 💬 [1] Neuroactive ligand-receptor interaction Prednisolone sodium phosphate 💬 Prednisolone phosphate [3] 3, 13, 97 💬
371 NR3C1 💬 [1] Neuroactive ligand-receptor interaction Hydrocortisone sodium succinate 💬 Hydrocortisone succinate [3] 81, 83, 97 💬
372 NR3C1 💬 [1] Neuroactive ligand-receptor interaction Prednisolone 💬 Prednisolone [48] 3, 11, 13, 14, 18, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 54, 56, 57, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 111, 113, 145, 162, 222, 223, 251, 269, 271, 296, 299, 300 💬
373 NR3C1 💬 [1] Neuroactive ligand-receptor interaction Hydrocortisone acetate 💬 Hydrocortisone acetate [1] 97 💬
374 NR3C1 💬 [1] Neuroactive ligand-receptor interaction Beclometasone 💬 Beclomethasone dipropionate [2] 97, 98 💬
375 NR3C1 💬 [1] Neuroactive ligand-receptor interaction Prednisone 💬 Prednisone [58] 2, 11, 13, 14, 18, 19, 26, 28, 35, 40, 41, 42, 43, 44, 45, 46, 48, 49, 50, 51, 53, 60, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 90, 93, 95, 96, 97, 113, 127, 145, 162, 164, 205, 222, 223, 224, 228, 251, 269, 283, 284, 285, 288, 299, 300, 303, 307, 331 💬
376 OPRD1 💬 [5] cGMP-PKG signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling Naltrexone hydrochloride 💬 Naltrexone [14] 6, 10, 13, 40, 41, 42, 43, 44, 45, 46, 49, 96, 97, 226 💬
377 OPRD1 💬 [5] cGMP-PKG signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling Naltrexone 💬 Naltrexone [14] 6, 10, 13, 40, 41, 42, 43, 44, 45, 46, 49, 96, 97, 226 💬
378 OPRD1 💬 [5] cGMP-PKG signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling Loperamide 💬 Loperamide [2] 13, 97 💬
379 OPRD1 💬 [5] cGMP-PKG signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling Loperamide hydrochloride 💬 Loperamide [2] 13, 97 💬
380 OPRK1 💬 [3] Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling Naltrexone 💬 Naltrexone [14] 6, 10, 13, 40, 41, 42, 43, 44, 45, 46, 49, 96, 97, 226 💬
381 OPRK1 💬 [3] Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling Loperamide hydrochloride 💬 Loperamide [2] 13, 97 💬
382 OPRK1 💬 [3] Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling Naltrexone hydrochloride 💬 Naltrexone [14] 6, 10, 13, 40, 41, 42, 43, 44, 45, 46, 49, 96, 97, 226 💬
383 OPRK1 💬 [3] Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling Loperamide 💬 Loperamide [2] 13, 97 💬
384 OPRM1 💬 [5] Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Estrogen signaling pathway, Morphine addiction Naltrexone 💬 Naltrexone [14] 6, 10, 13, 40, 41, 42, 43, 44, 45, 46, 49, 96, 97, 226 💬
385 OPRM1 💬 [5] Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Estrogen signaling pathway, Morphine addiction Loperamide 💬 Loperamide [2] 13, 97 💬
386 OPRM1 💬 [5] Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Estrogen signaling pathway, Morphine addiction Fentanyl citrate 💬 Fentanyl [6] 46, 70, 97, 215, 231, 298 💬
387 OPRM1 💬 [5] Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Estrogen signaling pathway, Morphine addiction Naltrexone hydrochloride 💬 Naltrexone [14] 6, 10, 13, 40, 41, 42, 43, 44, 45, 46, 49, 96, 97, 226 💬
388 OPRM1 💬 [5] Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Estrogen signaling pathway, Morphine addiction Fentanyl 💬 Fentanyl [6] 46, 70, 97, 215, 231, 298 💬
389 OPRM1 💬 [5] Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Estrogen signaling pathway, Morphine addiction Fentanyl hydrochloride 💬 Fentanyl [6] 46, 70, 97, 215, 231, 298 💬
390 OPRM1 💬 [5] Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Estrogen signaling pathway, Morphine addiction Loperamide hydrochloride 💬 Loperamide [2] 13, 97 💬
391 OSMR 💬 [3] Cytokine-cytokine receptor interaction, PI3K-Akt signaling pathway, JAK-STAT signaling pathway Vixarelimab 💬 Vixarelimab [3] 51, 85, 97 💬
392 PDCD1 💬 [3] Cell adhesion molecule (CAM) interaction, T cell receptor signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer Pembrolizumab 💬 Pembrolizumab [3] 25, 97, 285 💬
393 PDCD1 💬 [3] Cell adhesion molecule (CAM) interaction, T cell receptor signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer Nivolumab 💬 Nivolumab [12] 13, 26, 41, 46, 49, 50, 51, 53, 85, 96, 97, 159 💬
394 PDCD1 💬 [3] Cell adhesion molecule (CAM) interaction, T cell receptor signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer Rosnilimab 💬 Rosnilimab [2] 46, 97 💬
395 PDE1B 💬 [6] Purine metabolism, Calcium signaling pathway, Olfactory transduction, Taste transduction, Renin secretion, Morphine addiction Caffeine citrate 💬 Caffeine [8] 2, 6, 13, 21, 46, 96, 97, 265 💬
396 PDE1B 💬 [6] Purine metabolism, Calcium signaling pathway, Olfactory transduction, Taste transduction, Renin secretion, Morphine addiction Caffeine 💬 Caffeine [8] 2, 6, 13, 21, 46, 96, 97, 265 💬
397 PDE2A 💬 [5] Purine metabolism, cGMP-PKG signaling pathway, Olfactory transduction, Aldosterone synthesis and secretion, Morphine addiction Caffeine citrate 💬 Caffeine [8] 2, 6, 13, 21, 46, 96, 97, 265 💬
398 PDE2A 💬 [5] Purine metabolism, cGMP-PKG signaling pathway, Olfactory transduction, Aldosterone synthesis and secretion, Morphine addiction Caffeine 💬 Caffeine [8] 2, 6, 13, 21, 46, 96, 97, 265 💬
399 PDE3A 💬 [5] Purine metabolism, cGMP-PKG signaling pathway, cAMP signaling pathway, Renin secretion, Morphine addiction Caffeine citrate 💬 Caffeine [8] 2, 6, 13, 21, 46, 96, 97, 265 💬
400 PDE3A 💬 [5] Purine metabolism, cGMP-PKG signaling pathway, cAMP signaling pathway, Renin secretion, Morphine addiction Caffeine 💬 Caffeine [8] 2, 6, 13, 21, 46, 96, 97, 265 💬
401 PDE3B 💬 [10] Purine metabolism, cGMP-PKG signaling pathway, cAMP signaling pathway, Apelin signaling pathway, Insulin signaling pathway, Progesterone-mediated oocyte maturation, Glucagon signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Morphine addiction Caffeine 💬 Caffeine [8] 2, 6, 13, 21, 46, 96, 97, 265 💬
402 PDE3B 💬 [10] Purine metabolism, cGMP-PKG signaling pathway, cAMP signaling pathway, Apelin signaling pathway, Insulin signaling pathway, Progesterone-mediated oocyte maturation, Glucagon signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Morphine addiction Caffeine citrate 💬 Caffeine [8] 2, 6, 13, 21, 46, 96, 97, 265 💬
403 PDE4A 💬 [4] Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Roflumilast 💬 Roflumilast [5] 46, 84, 97, 206, 299 💬
404 PDE4A 💬 [4] Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Caffeine 💬 Caffeine [8] 2, 6, 13, 21, 46, 96, 97, 265 💬
405 PDE4A 💬 [4] Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Caffeine citrate 💬 Caffeine [8] 2, 6, 13, 21, 46, 96, 97, 265 💬
406 PDE4A 💬 [4] Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Apremilast 💬 Apremilast [8] 36, 46, 50, 56, 97, 107, 162, 271 💬
407 PDE4B 💬 [4] Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Caffeine citrate 💬 Caffeine [8] 2, 6, 13, 21, 46, 96, 97, 265 💬
408 PDE4B 💬 [4] Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Roflumilast 💬 Roflumilast [5] 46, 84, 97, 206, 299 💬
409 PDE4B 💬 [4] Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Apremilast 💬 Apremilast [8] 36, 46, 50, 56, 97, 107, 162, 271 💬
410 PDE4B 💬 [4] Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Caffeine 💬 Caffeine [8] 2, 6, 13, 21, 46, 96, 97, 265 💬
411 PDE4C 💬 [4] Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Roflumilast 💬 Roflumilast [5] 46, 84, 97, 206, 299 💬
412 PDE4C 💬 [4] Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Apremilast 💬 Apremilast [8] 36, 46, 50, 56, 97, 107, 162, 271 💬
413 PDE4C 💬 [4] Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Caffeine 💬 Caffeine [8] 2, 6, 13, 21, 46, 96, 97, 265 💬
414 PDE4C 💬 [4] Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Caffeine citrate 💬 Caffeine [8] 2, 6, 13, 21, 46, 96, 97, 265 💬
415 PDE4D 💬 [4] Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Caffeine 💬 Caffeine [8] 2, 6, 13, 21, 46, 96, 97, 265 💬
416 PDE4D 💬 [4] Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Caffeine citrate 💬 Caffeine [8] 2, 6, 13, 21, 46, 96, 97, 265 💬
417 PDE4D 💬 [4] Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Roflumilast 💬 Roflumilast [5] 46, 84, 97, 206, 299 💬
418 PDE4D 💬 [4] Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Apremilast 💬 Apremilast [8] 36, 46, 50, 56, 97, 107, 162, 271 💬
419 PDE5A 💬 [2] Purine metabolism, cGMP-PKG signaling pathway Caffeine 💬 Caffeine [8] 2, 6, 13, 21, 46, 96, 97, 265 💬
420 PDE5A 💬 [2] Purine metabolism, cGMP-PKG signaling pathway Caffeine citrate 💬 Caffeine [8] 2, 6, 13, 21, 46, 96, 97, 265 💬
421 PPARA 💬 [10] PPAR signaling pathway, cAMP signaling pathway, Adipocytokine signaling pathway, Glucagon signaling pathway, Insulin resistance, Non-alcoholic fatty liver disease, Alcoholic liver disease, Hepatitis C, Chemical carcinogenesis - receptor activation, Diabetic cardiomyopathy Fenofibrate 💬 Fenofibrate [6] 8, 79, 93, 94, 97, 265 💬
422 PPARG 💬 [12] PPAR signaling pathway, Efferocytosis, AMPK signaling pathway, Longevity regulating pathway, Osteoclast differentiation, Thermogenesis, Non-alcoholic fatty liver disease, Huntington disease, Pathways in cancer, Transcriptional misregulation in cancer, Thyroid cancer, Lipid and atherosclerosis Rosiglitazone maleate 💬 Rosiglitazone [7] 46, 57, 75, 77, 97, 222, 265 💬
423 PPARG 💬 [12] PPAR signaling pathway, Efferocytosis, AMPK signaling pathway, Longevity regulating pathway, Osteoclast differentiation, Thermogenesis, Non-alcoholic fatty liver disease, Huntington disease, Pathways in cancer, Transcriptional misregulation in cancer, Thyroid cancer, Lipid and atherosclerosis Rosiglitazone 💬 Rosiglitazone [7] 46, 57, 75, 77, 97, 222, 265 💬
424 PPP3CA 💬 [33] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, Oocyte meiosis, Cellular senescence, Wnt signaling pathway, Axon guidance, VEGF signaling pathway, Osteoclast differentiation, C-type lectin receptor signaling pathway, Natural killer cell mediated cytotoxicity, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, B cell receptor signaling pathway, Long-term potentiation, Glutamatergic synapse, Dopaminergic synapse, Oxytocin signaling pathway, Glucagon signaling pathway, Renin secretion, Alzheimer disease, Amyotrophic lateral sclerosis, Prion disease, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Tuberculosis, Human cytomegalovirus infection, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Human immunodeficiency virus 1 infection, PD-L1 expression and PD-1 checkpoint pathway in cancer, Lipid and atherosclerosis Cyclosporine 💬 Cyclosporine [39] 11, 14, 19, 20, 28, 36, 40, 41, 42, 45, 46, 49, 50, 53, 56, 58, 60, 61, 62, 63, 64, 65, 67, 90, 95, 97, 107, 118, 162, 164, 222, 223, 226, 228, 234, 283, 284, 285, 302 💬
425 PPP3CA 💬 [33] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, Oocyte meiosis, Cellular senescence, Wnt signaling pathway, Axon guidance, VEGF signaling pathway, Osteoclast differentiation, C-type lectin receptor signaling pathway, Natural killer cell mediated cytotoxicity, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, B cell receptor signaling pathway, Long-term potentiation, Glutamatergic synapse, Dopaminergic synapse, Oxytocin signaling pathway, Glucagon signaling pathway, Renin secretion, Alzheimer disease, Amyotrophic lateral sclerosis, Prion disease, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Tuberculosis, Human cytomegalovirus infection, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Human immunodeficiency virus 1 infection, PD-L1 expression and PD-1 checkpoint pathway in cancer, Lipid and atherosclerosis Tacrolimus 💬 Tacrolimus [37] 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 57, 60, 61, 62, 63, 65, 66, 95, 96, 97, 113, 151, 158, 164, 222, 223, 224, 226, 227, 228, 234, 283, 284, 285, 286, 299 💬
426 PPP3CA 💬 [33] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, Oocyte meiosis, Cellular senescence, Wnt signaling pathway, Axon guidance, VEGF signaling pathway, Osteoclast differentiation, C-type lectin receptor signaling pathway, Natural killer cell mediated cytotoxicity, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, B cell receptor signaling pathway, Long-term potentiation, Glutamatergic synapse, Dopaminergic synapse, Oxytocin signaling pathway, Glucagon signaling pathway, Renin secretion, Alzheimer disease, Amyotrophic lateral sclerosis, Prion disease, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Tuberculosis, Human cytomegalovirus infection, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Human immunodeficiency virus 1 infection, PD-L1 expression and PD-1 checkpoint pathway in cancer, Lipid and atherosclerosis Tacrolimus 💬 Tacrolimus [37] 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 57, 60, 61, 62, 63, 65, 66, 95, 96, 97, 113, 151, 158, 164, 222, 223, 224, 226, 227, 228, 234, 283, 284, 285, 286, 299 💬
427 PPP3CB 💬 [33] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, Oocyte meiosis, Cellular senescence, Wnt signaling pathway, Axon guidance, VEGF signaling pathway, Osteoclast differentiation, C-type lectin receptor signaling pathway, Natural killer cell mediated cytotoxicity, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, B cell receptor signaling pathway, Long-term potentiation, Glutamatergic synapse, Dopaminergic synapse, Oxytocin signaling pathway, Glucagon signaling pathway, Renin secretion, Alzheimer disease, Amyotrophic lateral sclerosis, Prion disease, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Tuberculosis, Human cytomegalovirus infection, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Human immunodeficiency virus 1 infection, PD-L1 expression and PD-1 checkpoint pathway in cancer, Lipid and atherosclerosis Cyclosporine 💬 Cyclosporine [39] 11, 14, 19, 20, 28, 36, 40, 41, 42, 45, 46, 49, 50, 53, 56, 58, 60, 61, 62, 63, 64, 65, 67, 90, 95, 97, 107, 118, 162, 164, 222, 223, 226, 228, 234, 283, 284, 285, 302 💬
428 PPP3CB 💬 [33] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, Oocyte meiosis, Cellular senescence, Wnt signaling pathway, Axon guidance, VEGF signaling pathway, Osteoclast differentiation, C-type lectin receptor signaling pathway, Natural killer cell mediated cytotoxicity, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, B cell receptor signaling pathway, Long-term potentiation, Glutamatergic synapse, Dopaminergic synapse, Oxytocin signaling pathway, Glucagon signaling pathway, Renin secretion, Alzheimer disease, Amyotrophic lateral sclerosis, Prion disease, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Tuberculosis, Human cytomegalovirus infection, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Human immunodeficiency virus 1 infection, PD-L1 expression and PD-1 checkpoint pathway in cancer, Lipid and atherosclerosis Tacrolimus 💬 Tacrolimus [37] 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 57, 60, 61, 62, 63, 65, 66, 95, 96, 97, 113, 151, 158, 164, 222, 223, 224, 226, 227, 228, 234, 283, 284, 285, 286, 299 💬
429 PPP3CB 💬 [33] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, Oocyte meiosis, Cellular senescence, Wnt signaling pathway, Axon guidance, VEGF signaling pathway, Osteoclast differentiation, C-type lectin receptor signaling pathway, Natural killer cell mediated cytotoxicity, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, B cell receptor signaling pathway, Long-term potentiation, Glutamatergic synapse, Dopaminergic synapse, Oxytocin signaling pathway, Glucagon signaling pathway, Renin secretion, Alzheimer disease, Amyotrophic lateral sclerosis, Prion disease, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Tuberculosis, Human cytomegalovirus infection, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Human immunodeficiency virus 1 infection, PD-L1 expression and PD-1 checkpoint pathway in cancer, Lipid and atherosclerosis Tacrolimus 💬 Tacrolimus [37] 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 57, 60, 61, 62, 63, 65, 66, 95, 96, 97, 113, 151, 158, 164, 222, 223, 224, 226, 227, 228, 234, 283, 284, 285, 286, 299 💬
430 PPP3CC 💬 [33] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, Oocyte meiosis, Cellular senescence, Wnt signaling pathway, Axon guidance, VEGF signaling pathway, Osteoclast differentiation, C-type lectin receptor signaling pathway, Natural killer cell mediated cytotoxicity, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, B cell receptor signaling pathway, Long-term potentiation, Glutamatergic synapse, Dopaminergic synapse, Oxytocin signaling pathway, Glucagon signaling pathway, Renin secretion, Alzheimer disease, Amyotrophic lateral sclerosis, Prion disease, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Tuberculosis, Human cytomegalovirus infection, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Human immunodeficiency virus 1 infection, PD-L1 expression and PD-1 checkpoint pathway in cancer, Lipid and atherosclerosis Tacrolimus 💬 Tacrolimus [37] 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 57, 60, 61, 62, 63, 65, 66, 95, 96, 97, 113, 151, 158, 164, 222, 223, 224, 226, 227, 228, 234, 283, 284, 285, 286, 299 💬
431 PPP3CC 💬 [33] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, Oocyte meiosis, Cellular senescence, Wnt signaling pathway, Axon guidance, VEGF signaling pathway, Osteoclast differentiation, C-type lectin receptor signaling pathway, Natural killer cell mediated cytotoxicity, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, B cell receptor signaling pathway, Long-term potentiation, Glutamatergic synapse, Dopaminergic synapse, Oxytocin signaling pathway, Glucagon signaling pathway, Renin secretion, Alzheimer disease, Amyotrophic lateral sclerosis, Prion disease, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Tuberculosis, Human cytomegalovirus infection, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Human immunodeficiency virus 1 infection, PD-L1 expression and PD-1 checkpoint pathway in cancer, Lipid and atherosclerosis Tacrolimus 💬 Tacrolimus [37] 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 57, 60, 61, 62, 63, 65, 66, 95, 96, 97, 113, 151, 158, 164, 222, 223, 224, 226, 227, 228, 234, 283, 284, 285, 286, 299 💬
432 PPP3CC 💬 [33] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, Oocyte meiosis, Cellular senescence, Wnt signaling pathway, Axon guidance, VEGF signaling pathway, Osteoclast differentiation, C-type lectin receptor signaling pathway, Natural killer cell mediated cytotoxicity, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, B cell receptor signaling pathway, Long-term potentiation, Glutamatergic synapse, Dopaminergic synapse, Oxytocin signaling pathway, Glucagon signaling pathway, Renin secretion, Alzheimer disease, Amyotrophic lateral sclerosis, Prion disease, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Tuberculosis, Human cytomegalovirus infection, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Human immunodeficiency virus 1 infection, PD-L1 expression and PD-1 checkpoint pathway in cancer, Lipid and atherosclerosis Cyclosporine 💬 Cyclosporine [39] 11, 14, 19, 20, 28, 36, 40, 41, 42, 45, 46, 49, 50, 53, 56, 58, 60, 61, 62, 63, 64, 65, 67, 90, 95, 97, 107, 118, 162, 164, 222, 223, 226, 228, 234, 283, 284, 285, 302 💬
433 PPP3R1 💬 [32] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, Oocyte meiosis, Cellular senescence, Wnt signaling pathway, Axon guidance, VEGF signaling pathway, Osteoclast differentiation, C-type lectin receptor signaling pathway, Natural killer cell mediated cytotoxicity, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, B cell receptor signaling pathway, Long-term potentiation, Glutamatergic synapse, Oxytocin signaling pathway, Glucagon signaling pathway, Renin secretion, Alzheimer disease, Amyotrophic lateral sclerosis, Prion disease, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Tuberculosis, Human cytomegalovirus infection, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Human immunodeficiency virus 1 infection, PD-L1 expression and PD-1 checkpoint pathway in cancer, Lipid and atherosclerosis Cyclosporine 💬 Cyclosporine [39] 11, 14, 19, 20, 28, 36, 40, 41, 42, 45, 46, 49, 50, 53, 56, 58, 60, 61, 62, 63, 64, 65, 67, 90, 95, 97, 107, 118, 162, 164, 222, 223, 226, 228, 234, 283, 284, 285, 302 💬
434 PPP3R1 💬 [32] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, Oocyte meiosis, Cellular senescence, Wnt signaling pathway, Axon guidance, VEGF signaling pathway, Osteoclast differentiation, C-type lectin receptor signaling pathway, Natural killer cell mediated cytotoxicity, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, B cell receptor signaling pathway, Long-term potentiation, Glutamatergic synapse, Oxytocin signaling pathway, Glucagon signaling pathway, Renin secretion, Alzheimer disease, Amyotrophic lateral sclerosis, Prion disease, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Tuberculosis, Human cytomegalovirus infection, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Human immunodeficiency virus 1 infection, PD-L1 expression and PD-1 checkpoint pathway in cancer, Lipid and atherosclerosis Tacrolimus 💬 Tacrolimus [37] 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 57, 60, 61, 62, 63, 65, 66, 95, 96, 97, 113, 151, 158, 164, 222, 223, 224, 226, 227, 228, 234, 283, 284, 285, 286, 299 💬
435 PPP3R1 💬 [32] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, Oocyte meiosis, Cellular senescence, Wnt signaling pathway, Axon guidance, VEGF signaling pathway, Osteoclast differentiation, C-type lectin receptor signaling pathway, Natural killer cell mediated cytotoxicity, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, B cell receptor signaling pathway, Long-term potentiation, Glutamatergic synapse, Oxytocin signaling pathway, Glucagon signaling pathway, Renin secretion, Alzheimer disease, Amyotrophic lateral sclerosis, Prion disease, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Tuberculosis, Human cytomegalovirus infection, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Human immunodeficiency virus 1 infection, PD-L1 expression and PD-1 checkpoint pathway in cancer, Lipid and atherosclerosis Tacrolimus 💬 Tacrolimus [37] 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 57, 60, 61, 62, 63, 65, 66, 95, 96, 97, 113, 151, 158, 164, 222, 223, 224, 226, 227, 228, 234, 283, 284, 285, 286, 299 💬
436 PPP3R2 💬 [32] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, Oocyte meiosis, Cellular senescence, Wnt signaling pathway, Axon guidance, VEGF signaling pathway, Osteoclast differentiation, C-type lectin receptor signaling pathway, Natural killer cell mediated cytotoxicity, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, B cell receptor signaling pathway, Long-term potentiation, Glutamatergic synapse, Oxytocin signaling pathway, Glucagon signaling pathway, Renin secretion, Alzheimer disease, Amyotrophic lateral sclerosis, Prion disease, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Tuberculosis, Human cytomegalovirus infection, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Human immunodeficiency virus 1 infection, PD-L1 expression and PD-1 checkpoint pathway in cancer, Lipid and atherosclerosis Cyclosporine 💬 Cyclosporine [39] 11, 14, 19, 20, 28, 36, 40, 41, 42, 45, 46, 49, 50, 53, 56, 58, 60, 61, 62, 63, 64, 65, 67, 90, 95, 97, 107, 118, 162, 164, 222, 223, 226, 228, 234, 283, 284, 285, 302 💬
437 PPP3R2 💬 [32] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, Oocyte meiosis, Cellular senescence, Wnt signaling pathway, Axon guidance, VEGF signaling pathway, Osteoclast differentiation, C-type lectin receptor signaling pathway, Natural killer cell mediated cytotoxicity, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, B cell receptor signaling pathway, Long-term potentiation, Glutamatergic synapse, Oxytocin signaling pathway, Glucagon signaling pathway, Renin secretion, Alzheimer disease, Amyotrophic lateral sclerosis, Prion disease, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Tuberculosis, Human cytomegalovirus infection, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Human immunodeficiency virus 1 infection, PD-L1 expression and PD-1 checkpoint pathway in cancer, Lipid and atherosclerosis Tacrolimus 💬 Tacrolimus [37] 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 57, 60, 61, 62, 63, 65, 66, 95, 96, 97, 113, 151, 158, 164, 222, 223, 224, 226, 227, 228, 234, 283, 284, 285, 286, 299 💬
438 PPP3R2 💬 [32] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, Oocyte meiosis, Cellular senescence, Wnt signaling pathway, Axon guidance, VEGF signaling pathway, Osteoclast differentiation, C-type lectin receptor signaling pathway, Natural killer cell mediated cytotoxicity, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, B cell receptor signaling pathway, Long-term potentiation, Glutamatergic synapse, Oxytocin signaling pathway, Glucagon signaling pathway, Renin secretion, Alzheimer disease, Amyotrophic lateral sclerosis, Prion disease, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Tuberculosis, Human cytomegalovirus infection, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Human immunodeficiency virus 1 infection, PD-L1 expression and PD-1 checkpoint pathway in cancer, Lipid and atherosclerosis Tacrolimus 💬 Tacrolimus [37] 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 57, 60, 61, 62, 63, 65, 66, 95, 96, 97, 113, 151, 158, 164, 222, 223, 224, 226, 227, 228, 234, 283, 284, 285, 286, 299 💬
439 PRKAA1 💬 [20] FoxO signaling pathway, Autophagy - animal, mTOR signaling pathway, PI3K-Akt signaling pathway, AMPK signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Apelin signaling pathway, Tight junction, Circadian rhythm, Thermogenesis, Insulin signaling pathway, Adipocytokine signaling pathway, Oxytocin signaling pathway, Glucagon signaling pathway, Insulin resistance, Non-alcoholic fatty liver disease, Alcoholic liver disease, Hypertrophic cardiomyopathy, Fluid shear stress and atherosclerosis Metformin hydrochloride 💬 Metformin [31] 2, 6, 8, 13, 46, 49, 60, 65, 66, 67, 74, 75, 77, 81, 84, 85, 86, 97, 113, 127, 158, 206, 218, 222, 225, 233, 265, 285, 298, 299, 301 💬
440 PRKAA1 💬 [20] FoxO signaling pathway, Autophagy - animal, mTOR signaling pathway, PI3K-Akt signaling pathway, AMPK signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Apelin signaling pathway, Tight junction, Circadian rhythm, Thermogenesis, Insulin signaling pathway, Adipocytokine signaling pathway, Oxytocin signaling pathway, Glucagon signaling pathway, Insulin resistance, Non-alcoholic fatty liver disease, Alcoholic liver disease, Hypertrophic cardiomyopathy, Fluid shear stress and atherosclerosis Metformin 💬 Metformin [31] 2, 6, 8, 13, 46, 49, 60, 65, 66, 67, 74, 75, 77, 81, 84, 85, 86, 97, 113, 127, 158, 206, 218, 222, 225, 233, 265, 285, 298, 299, 301 💬
441 PRKAA2 💬 [20] FoxO signaling pathway, Autophagy - animal, mTOR signaling pathway, PI3K-Akt signaling pathway, AMPK signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Apelin signaling pathway, Tight junction, Circadian rhythm, Thermogenesis, Insulin signaling pathway, Adipocytokine signaling pathway, Oxytocin signaling pathway, Glucagon signaling pathway, Insulin resistance, Non-alcoholic fatty liver disease, Alcoholic liver disease, Hypertrophic cardiomyopathy, Fluid shear stress and atherosclerosis Metformin 💬 Metformin [31] 2, 6, 8, 13, 46, 49, 60, 65, 66, 67, 74, 75, 77, 81, 84, 85, 86, 97, 113, 127, 158, 206, 218, 222, 225, 233, 265, 285, 298, 299, 301 💬
442 PRKAA2 💬 [20] FoxO signaling pathway, Autophagy - animal, mTOR signaling pathway, PI3K-Akt signaling pathway, AMPK signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Apelin signaling pathway, Tight junction, Circadian rhythm, Thermogenesis, Insulin signaling pathway, Adipocytokine signaling pathway, Oxytocin signaling pathway, Glucagon signaling pathway, Insulin resistance, Non-alcoholic fatty liver disease, Alcoholic liver disease, Hypertrophic cardiomyopathy, Fluid shear stress and atherosclerosis Metformin hydrochloride 💬 Metformin [31] 2, 6, 8, 13, 46, 49, 60, 65, 66, 67, 74, 75, 77, 81, 84, 85, 86, 97, 113, 127, 158, 206, 218, 222, 225, 233, 265, 285, 298, 299, 301 💬
443 PRKCD 💬 [17] Chemokine signaling pathway, Autophagy - animal, Vascular smooth muscle contraction, NOD-like receptor signaling pathway, C-type lectin receptor signaling pathway, Fc gamma R-mediated phagosome formation, Neurotrophin signaling pathway, Inflammatory mediator regulation of TRP channels, GnRH signaling pathway, Estrogen signaling pathway, Type II diabetes mellitus, Insulin resistance, AGE-RAGE signaling pathway in diabetic complications, Prion disease, Shigellosis, Chemical carcinogenesis - reactive oxygen species, Diabetic cardiomyopathy Sotrastaurin 💬 Sotrastaurin [1] 97 💬
444 PRKCD 💬 [17] Chemokine signaling pathway, Autophagy - animal, Vascular smooth muscle contraction, NOD-like receptor signaling pathway, C-type lectin receptor signaling pathway, Fc gamma R-mediated phagosome formation, Neurotrophin signaling pathway, Inflammatory mediator regulation of TRP channels, GnRH signaling pathway, Estrogen signaling pathway, Type II diabetes mellitus, Insulin resistance, AGE-RAGE signaling pathway in diabetic complications, Prion disease, Shigellosis, Chemical carcinogenesis - reactive oxygen species, Diabetic cardiomyopathy Sotrastaurin acetate 💬 Sotrastaurin [1] 97 💬
445 PRKCE 💬 [13] cGMP-PKG signaling pathway, Sphingolipid signaling pathway, Vascular smooth muscle contraction, Apelin signaling pathway, Tight junction, Fc gamma R-mediated phagosome formation, Inflammatory mediator regulation of TRP channels, Aldosterone synthesis and secretion, Type II diabetes mellitus, Insulin resistance, AGE-RAGE signaling pathway in diabetic complications, Shigellosis, MicroRNAs in cancer Sotrastaurin 💬 Sotrastaurin [1] 97 💬
446 PRKCE 💬 [13] cGMP-PKG signaling pathway, Sphingolipid signaling pathway, Vascular smooth muscle contraction, Apelin signaling pathway, Tight junction, Fc gamma R-mediated phagosome formation, Inflammatory mediator regulation of TRP channels, Aldosterone synthesis and secretion, Type II diabetes mellitus, Insulin resistance, AGE-RAGE signaling pathway in diabetic complications, Shigellosis, MicroRNAs in cancer Sotrastaurin acetate 💬 Sotrastaurin [1] 97 💬
447 PRKCH 💬 [2] Vascular smooth muscle contraction, Inflammatory mediator regulation of TRP channels Sotrastaurin 💬 Sotrastaurin [1] 97 💬
448 PRKCH 💬 [2] Vascular smooth muscle contraction, Inflammatory mediator regulation of TRP channels Sotrastaurin acetate 💬 Sotrastaurin [1] 97 💬
449 PRKCQ 💬 [12] NF-kappa B signaling pathway, Autophagy - animal, Vascular smooth muscle contraction, IgSF CAM signaling, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Inflammatory mediator regulation of TRP channels, Adipocytokine signaling pathway, Insulin resistance, Shigellosis, PD-L1 expression and PD-1 checkpoint pathway in cancer Sotrastaurin acetate 💬 Sotrastaurin [1] 97 💬
450 PRKCQ 💬 [12] NF-kappa B signaling pathway, Autophagy - animal, Vascular smooth muscle contraction, IgSF CAM signaling, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Inflammatory mediator regulation of TRP channels, Adipocytokine signaling pathway, Insulin resistance, Shigellosis, PD-L1 expression and PD-1 checkpoint pathway in cancer Sotrastaurin 💬 Sotrastaurin [1] 97 💬
451 PTAFR 💬 [3] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Staphylococcus aureus infection Rupatadine fumarate 💬 Rupatadine [2] 46, 97 💬
452 PTAFR 💬 [3] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Staphylococcus aureus infection Rupatadine 💬 Rupatadine [2] 46, 97 💬
453 PTGS1 💬 [4] Arachidonic acid metabolism, Platelet activation, Serotonergic synapse, Regulation of lipolysis in adipocytes Sodium salicylate 💬 Salicylic acid [1] 97 💬
454 PTGS2 💬 [22] Arachidonic acid metabolism, NF-kappa B signaling pathway, Efferocytosis, VEGF signaling pathway, C-type lectin receptor signaling pathway, IL-17 signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Ovarian steroidogenesis, Oxytocin signaling pathway, Regulation of lipolysis in adipocytes, Alzheimer disease, Pathways of neurodegeneration - multiple diseases, Leishmaniasis, Human cytomegalovirus infection, Human papillomavirus infection, Kaposi sarcoma-associated herpesvirus infection, Pathways in cancer, Chemical carcinogenesis - DNA adducts, MicroRNAs in cancer, Small cell lung cancer Celecoxib 💬 Celecoxib [14] 2, 3, 6, 13, 34, 46, 70, 89, 96, 97, 107, 161, 171, 271 💬
455 PTGS2 💬 [22] Arachidonic acid metabolism, NF-kappa B signaling pathway, Efferocytosis, VEGF signaling pathway, C-type lectin receptor signaling pathway, IL-17 signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Ovarian steroidogenesis, Oxytocin signaling pathway, Regulation of lipolysis in adipocytes, Alzheimer disease, Pathways of neurodegeneration - multiple diseases, Leishmaniasis, Human cytomegalovirus infection, Human papillomavirus infection, Kaposi sarcoma-associated herpesvirus infection, Pathways in cancer, Chemical carcinogenesis - DNA adducts, MicroRNAs in cancer, Small cell lung cancer Sodium salicylate 💬 Salicylic acid [1] 97 💬
456 RARA 💬 [5] Th17 cell differentiation, Estrogen signaling pathway, Pathways in cancer, Transcriptional misregulation in cancer, Acute myeloid leukemia Vitamin A 💬 Vitamin A [4] 13, 53, 90, 97 💬
457 RARB 💬 [4] Pathways in cancer, Small cell lung cancer, Non-small cell lung cancer, Gastric cancer Vitamin A 💬 Vitamin A [4] 13, 53, 90, 97 💬
458 RIPK1 💬 [16] NF-kappa B signaling pathway, Apoptosis, Necroptosis, Toll-like receptor signaling pathway, NOD-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Cytosolic DNA-sensing pathway, TNF signaling pathway, Alcoholic liver disease, Pathogenic Escherichia coli infection, Shigellosis, Salmonella infection, Hepatitis C, Human cytomegalovirus infection, Epstein-Barr virus infection, Human immunodeficiency virus 1 infection Eclitasertib 💬 SAR443122 [1] 97 💬
459 S1PR1 💬 [4] FoxO signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction, Efferocytosis Ozanimod 💬 Ozanimod [3] 13, 96, 97 💬
460 S1PR1 💬 [4] FoxO signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction, Efferocytosis Etrasimod 💬 Etrasimod [3] 96, 97, 98 💬
461 S1PR1 💬 [4] FoxO signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction, Efferocytosis Etrasimod arginine 💬 Etrasimod [3] 96, 97, 98 💬
462 S1PR1 💬 [4] FoxO signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction, Efferocytosis Ozanimod hydrochloride 💬 Ozanimod [3] 13, 96, 97 💬
463 S1PR1 💬 [4] FoxO signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction, Efferocytosis Amiselimod 💬 Amiselimod [1] 97 💬
464 S1PR2 💬 [2] Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction Amiselimod 💬 Amiselimod [1] 97 💬
465 S1PR2 💬 [2] Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction Ozanimod hydrochloride 💬 Ozanimod [3] 13, 96, 97 💬
466 S1PR2 💬 [2] Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction Ozanimod 💬 Ozanimod [3] 13, 96, 97 💬
467 S1PR3 💬 [2] Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction Ozanimod hydrochloride 💬 Ozanimod [3] 13, 96, 97 💬
468 S1PR3 💬 [2] Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction Ozanimod 💬 Ozanimod [3] 13, 96, 97 💬
469 S1PR3 💬 [2] Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction Amiselimod 💬 Amiselimod [1] 97 💬
470 S1PR4 💬 [3] FoxO signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction Ozanimod hydrochloride 💬 Ozanimod [3] 13, 96, 97 💬
471 S1PR4 💬 [3] FoxO signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction Etrasimod arginine 💬 Etrasimod [3] 96, 97, 98 💬
472 S1PR4 💬 [3] FoxO signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction Ozanimod 💬 Ozanimod [3] 13, 96, 97 💬
473 S1PR4 💬 [3] FoxO signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction Etrasimod 💬 Etrasimod [3] 96, 97, 98 💬
474 S1PR4 💬 [3] FoxO signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction Amiselimod 💬 Amiselimod [1] 97 💬
475 S1PR5 💬 [2] Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction Etrasimod 💬 Etrasimod [3] 96, 97, 98 💬
476 S1PR5 💬 [2] Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction Ozanimod 💬 Ozanimod [3] 13, 96, 97 💬
477 S1PR5 💬 [2] Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction Ozanimod hydrochloride 💬 Ozanimod [3] 13, 96, 97 💬
478 S1PR5 💬 [2] Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction Amiselimod 💬 Amiselimod [1] 97 💬
479 S1PR5 💬 [2] Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction Etrasimod arginine 💬 Etrasimod [3] 96, 97, 98 💬
480 SCN1A 💬 [1] Dopaminergic synapse Ropivacaine hydrochloride 💬 Ropivacaine [7] 22, 36, 46, 63, 70, 71, 97 💬
481 SCN1A 💬 [1] Dopaminergic synapse Bupivacaine hydrochloride 💬 Bupivacaine [10] 46, 51, 53, 70, 71, 96, 97, 168, 226, 298 💬
482 SCN1A 💬 [1] Dopaminergic synapse Ropivacaine 💬 Ropivacaine [7] 22, 36, 46, 63, 70, 71, 97 💬
483 SCN1A 💬 [1] Dopaminergic synapse Topiramate 💬 Topiramate [6] 6, 97, 140, 144, 156, 193 💬
484 SCN1A 💬 [1] Dopaminergic synapse Bupivacaine 💬 Bupivacaine [10] 46, 51, 53, 70, 71, 96, 97, 168, 226, 298 💬
485 SCN2A 💬 [1] Taste transduction Bupivacaine hydrochloride 💬 Bupivacaine [10] 46, 51, 53, 70, 71, 96, 97, 168, 226, 298 💬
486 SCN2A 💬 [1] Taste transduction Topiramate 💬 Topiramate [6] 6, 97, 140, 144, 156, 193 💬
487 SCN2A 💬 [1] Taste transduction Ropivacaine 💬 Ropivacaine [7] 22, 36, 46, 63, 70, 71, 97 💬
488 SCN2A 💬 [1] Taste transduction Ropivacaine hydrochloride 💬 Ropivacaine [7] 22, 36, 46, 63, 70, 71, 97 💬
489 SCN2A 💬 [1] Taste transduction Bupivacaine 💬 Bupivacaine [10] 46, 51, 53, 70, 71, 96, 97, 168, 226, 298 💬
490 SCN3A 💬 [1] Taste transduction Ropivacaine 💬 Ropivacaine [7] 22, 36, 46, 63, 70, 71, 97 💬
491 SCN3A 💬 [1] Taste transduction Bupivacaine hydrochloride 💬 Bupivacaine [10] 46, 51, 53, 70, 71, 96, 97, 168, 226, 298 💬
492 SCN3A 💬 [1] Taste transduction Ropivacaine hydrochloride 💬 Ropivacaine [7] 22, 36, 46, 63, 70, 71, 97 💬
493 SCN3A 💬 [1] Taste transduction Bupivacaine 💬 Bupivacaine [10] 46, 51, 53, 70, 71, 96, 97, 168, 226, 298 💬
494 SCN3A 💬 [1] Taste transduction Topiramate 💬 Topiramate [6] 6, 97, 140, 144, 156, 193 💬
495 SCN5A 💬 [2] Adrenergic signaling in cardiomyocytes, Cadherin signaling Bupivacaine hydrochloride 💬 Bupivacaine [10] 46, 51, 53, 70, 71, 96, 97, 168, 226, 298 💬
496 SCN5A 💬 [2] Adrenergic signaling in cardiomyocytes, Cadherin signaling Topiramate 💬 Topiramate [6] 6, 97, 140, 144, 156, 193 💬
497 SCN5A 💬 [2] Adrenergic signaling in cardiomyocytes, Cadherin signaling Bupivacaine 💬 Bupivacaine [10] 46, 51, 53, 70, 71, 96, 97, 168, 226, 298 💬
498 SCN5A 💬 [2] Adrenergic signaling in cardiomyocytes, Cadherin signaling Ropivacaine hydrochloride 💬 Ropivacaine [7] 22, 36, 46, 63, 70, 71, 97 💬
499 SCN5A 💬 [2] Adrenergic signaling in cardiomyocytes, Cadherin signaling Ropivacaine 💬 Ropivacaine [7] 22, 36, 46, 63, 70, 71, 97 💬
500 SCN8A 💬 [1] IgSF CAM signaling Topiramate 💬 Topiramate [6] 6, 97, 140, 144, 156, 193 💬
501 SCN8A 💬 [1] IgSF CAM signaling Bupivacaine hydrochloride 💬 Bupivacaine [10] 46, 51, 53, 70, 71, 96, 97, 168, 226, 298 💬
502 SCN8A 💬 [1] IgSF CAM signaling Ropivacaine 💬 Ropivacaine [7] 22, 36, 46, 63, 70, 71, 97 💬
503 SCN8A 💬 [1] IgSF CAM signaling Ropivacaine hydrochloride 💬 Ropivacaine [7] 22, 36, 46, 63, 70, 71, 97 💬
504 SCN8A 💬 [1] IgSF CAM signaling Bupivacaine 💬 Bupivacaine [10] 46, 51, 53, 70, 71, 96, 97, 168, 226, 298 💬
505 SCN9A 💬 [1] Taste transduction Topiramate 💬 Topiramate [6] 6, 97, 140, 144, 156, 193 💬
506 SCN9A 💬 [1] Taste transduction Ropivacaine 💬 Ropivacaine [7] 22, 36, 46, 63, 70, 71, 97 💬
507 SCN9A 💬 [1] Taste transduction Bupivacaine 💬 Bupivacaine [10] 46, 51, 53, 70, 71, 96, 97, 168, 226, 298 💬
508 SCN9A 💬 [1] Taste transduction Ropivacaine hydrochloride 💬 Ropivacaine [7] 22, 36, 46, 63, 70, 71, 97 💬
509 SCN9A 💬 [1] Taste transduction Bupivacaine hydrochloride 💬 Bupivacaine [10] 46, 51, 53, 70, 71, 96, 97, 168, 226, 298 💬
510 SERPINC1 💬 [1] Complement and coagulation cascades Parnaparin sodium 💬 Parnaparin [1] 97 💬
511 SIGMAR1 💬 [2] Amyotrophic lateral sclerosis, Pathways of neurodegeneration - multiple diseases Dextromethorphan 💬 Dextromethorphan [10] 2, 6, 8, 13, 21, 46, 85, 96, 97, 156 💬
512 SIGMAR1 💬 [2] Amyotrophic lateral sclerosis, Pathways of neurodegeneration - multiple diseases Dextromethorphan hydrobromide 💬 Dextromethorphan [10] 2, 6, 8, 13, 21, 46, 85, 96, 97, 156 💬
513 SIGMAR1 💬 [2] Amyotrophic lateral sclerosis, Pathways of neurodegeneration - multiple diseases Dextromethorphan polistirex 💬 Dextromethorphan [10] 2, 6, 8, 13, 21, 46, 85, 96, 97, 156 💬
514 SLC6A2 💬 [2] Neuroactive ligand signaling, Synaptic vesicle cycle Venlafaxine hydrochloride 💬 Venlafaxine [4] 6, 13, 46, 97 💬
515 SLC6A2 💬 [2] Neuroactive ligand signaling, Synaptic vesicle cycle Duloxetine 💬 Duloxetine [3] 6, 13, 97 💬
516 SLC6A2 💬 [2] Neuroactive ligand signaling, Synaptic vesicle cycle Phentermine 💬 Phentermine [1] 97 💬
517 SLC6A2 💬 [2] Neuroactive ligand signaling, Synaptic vesicle cycle Amitriptyline 💬 Amitriptyline [4] 96, 97, 226, 299 💬
518 SLC6A2 💬 [2] Neuroactive ligand signaling, Synaptic vesicle cycle Venlafaxine besylate monohydrate 💬 Venlafaxine [4] 6, 13, 46, 97 💬
519 SLC6A2 💬 [2] Neuroactive ligand signaling, Synaptic vesicle cycle Duloxetine hydrochloride 💬 Duloxetine [3] 6, 13, 97 💬
520 SLC6A2 💬 [2] Neuroactive ligand signaling, Synaptic vesicle cycle Venlafaxine 💬 Venlafaxine [4] 6, 13, 46, 97 💬
521 SLC6A2 💬 [2] Neuroactive ligand signaling, Synaptic vesicle cycle Bupropion hydrochloride 💬 Bupropion [7] 8, 18, 21, 96, 97, 171, 298 💬
522 SLC6A2 💬 [2] Neuroactive ligand signaling, Synaptic vesicle cycle Bupropion 💬 Bupropion [7] 8, 18, 21, 96, 97, 171, 298 💬
523 SLC6A2 💬 [2] Neuroactive ligand signaling, Synaptic vesicle cycle Amitriptyline hydrochloride 💬 Amitriptyline [4] 96, 97, 226, 299 💬
524 SLC6A2 💬 [2] Neuroactive ligand signaling, Synaptic vesicle cycle Bupropion hydrobromide 💬 Bupropion [7] 8, 18, 21, 96, 97, 171, 298 💬
525 SLC6A2 💬 [2] Neuroactive ligand signaling, Synaptic vesicle cycle Phentermine hydrochloride 💬 Phentermine [1] 97 💬
526 SLC6A3 💬 [8] Neuroactive ligand signaling, Synaptic vesicle cycle, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Alcoholism Phentermine 💬 Phentermine [1] 97 💬
527 SLC6A3 💬 [8] Neuroactive ligand signaling, Synaptic vesicle cycle, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Alcoholism Bupropion hydrochloride 💬 Bupropion [7] 8, 18, 21, 96, 97, 171, 298 💬
528 SLC6A3 💬 [8] Neuroactive ligand signaling, Synaptic vesicle cycle, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Alcoholism Bupropion hydrobromide 💬 Bupropion [7] 8, 18, 21, 96, 97, 171, 298 💬
529 SLC6A3 💬 [8] Neuroactive ligand signaling, Synaptic vesicle cycle, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Alcoholism Bupropion 💬 Bupropion [7] 8, 18, 21, 96, 97, 171, 298 💬
530 SLC6A3 💬 [8] Neuroactive ligand signaling, Synaptic vesicle cycle, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Alcoholism Phentermine hydrochloride 💬 Phentermine [1] 97 💬
531 SLC6A4 💬 [3] Neuroactive ligand signaling, Synaptic vesicle cycle, Serotonergic synapse Duloxetine hydrochloride 💬 Duloxetine [3] 6, 13, 97 💬
532 SLC6A4 💬 [3] Neuroactive ligand signaling, Synaptic vesicle cycle, Serotonergic synapse Duloxetine 💬 Duloxetine [3] 6, 13, 97 💬
533 SLC6A4 💬 [3] Neuroactive ligand signaling, Synaptic vesicle cycle, Serotonergic synapse Venlafaxine besylate monohydrate 💬 Venlafaxine [4] 6, 13, 46, 97 💬
534 SLC6A4 💬 [3] Neuroactive ligand signaling, Synaptic vesicle cycle, Serotonergic synapse Venlafaxine hydrochloride 💬 Venlafaxine [4] 6, 13, 46, 97 💬
535 SLC6A4 💬 [3] Neuroactive ligand signaling, Synaptic vesicle cycle, Serotonergic synapse Phentermine hydrochloride 💬 Phentermine [1] 97 💬
536 SLC6A4 💬 [3] Neuroactive ligand signaling, Synaptic vesicle cycle, Serotonergic synapse Venlafaxine 💬 Venlafaxine [4] 6, 13, 46, 97 💬
537 SLC6A4 💬 [3] Neuroactive ligand signaling, Synaptic vesicle cycle, Serotonergic synapse Amitriptyline 💬 Amitriptyline [4] 96, 97, 226, 299 💬
538 SLC6A4 💬 [3] Neuroactive ligand signaling, Synaptic vesicle cycle, Serotonergic synapse Amitriptyline hydrochloride 💬 Amitriptyline [4] 96, 97, 226, 299 💬
539 SLC6A4 💬 [3] Neuroactive ligand signaling, Synaptic vesicle cycle, Serotonergic synapse Phentermine 💬 Phentermine [1] 97 💬
540 SMAD7 💬 [2] TGF-beta signaling pathway, Hippo signaling pathway Mongersen 💬 Mongersen [2] 96, 97 💬
541 TLR9 💬 [10] Lysosome biogenesis, Toll-like receptor signaling pathway, Salmonella infection, Chagas disease, African trypanosomiasis, Malaria, Tuberculosis, Measles, Herpes simplex virus 1 infection, PD-L1 expression and PD-1 checkpoint pathway in cancer Cobitolimod 💬 Cobitolimod [1] 97 💬
542 TNF 💬 [66] MAPK signaling pathway, Cytokine-cytokine receptor interaction, Viral protein interaction with cytokine and cytokine receptor, NF-kappa B signaling pathway, Sphingolipid signaling pathway, mTOR signaling pathway, Apoptosis, Necroptosis, TGF-beta signaling pathway, Osteoclast differentiation, Antigen processing and presentation, Toll-like receptor signaling pathway, NOD-like receptor signaling pathway, RIG-I-like receptor signaling pathway, C-type lectin receptor signaling pathway, Hematopoietic cell lineage, Natural killer cell mediated cytotoxicity, IL-17 signaling pathway, T cell receptor signaling pathway, Fc epsilon RI signaling pathway, TNF signaling pathway, Adipocytokine signaling pathway, Type II diabetes mellitus, Insulin resistance, Non-alcoholic fatty liver disease, AGE-RAGE signaling pathway in diabetic complications, Alcoholic liver disease, Type I diabetes mellitus, Alzheimer disease, Amyotrophic lateral sclerosis, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Shigellosis, Salmonella infection, Pertussis, Legionellosis, Yersinia infection, Leishmaniasis, Chagas disease, African trypanosomiasis, Malaria, Toxoplasmosis, Amoebiasis, Tuberculosis, Hepatitis C, Hepatitis B, Human cytomegalovirus infection, Influenza A, Human papillomavirus infection, Human T-cell leukemia virus 1 infection, Herpes simplex virus 1 infection, Epstein-Barr virus infection, Human immunodeficiency virus 1 infection, Coronavirus disease, Proteoglycans in cancer, Asthma, Inflammatory bowel disease, Systemic lupus erythematosus, Rheumatoid arthritis, Allograft rejection, Graft-versus-host disease, Hypertrophic cardiomyopathy, Dilated cardiomyopathy, Lipid and atherosclerosis, Fluid shear stress and atherosclerosis Certolizumab pegol 💬 Certolizumab pegol [10] 37, 40, 46, 48, 49, 96, 97, 107, 226, 271 💬
543 TNF 💬 [66] MAPK signaling pathway, Cytokine-cytokine receptor interaction, Viral protein interaction with cytokine and cytokine receptor, NF-kappa B signaling pathway, Sphingolipid signaling pathway, mTOR signaling pathway, Apoptosis, Necroptosis, TGF-beta signaling pathway, Osteoclast differentiation, Antigen processing and presentation, Toll-like receptor signaling pathway, NOD-like receptor signaling pathway, RIG-I-like receptor signaling pathway, C-type lectin receptor signaling pathway, Hematopoietic cell lineage, Natural killer cell mediated cytotoxicity, IL-17 signaling pathway, T cell receptor signaling pathway, Fc epsilon RI signaling pathway, TNF signaling pathway, Adipocytokine signaling pathway, Type II diabetes mellitus, Insulin resistance, Non-alcoholic fatty liver disease, AGE-RAGE signaling pathway in diabetic complications, Alcoholic liver disease, Type I diabetes mellitus, Alzheimer disease, Amyotrophic lateral sclerosis, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Shigellosis, Salmonella infection, Pertussis, Legionellosis, Yersinia infection, Leishmaniasis, Chagas disease, African trypanosomiasis, Malaria, Toxoplasmosis, Amoebiasis, Tuberculosis, Hepatitis C, Hepatitis B, Human cytomegalovirus infection, Influenza A, Human papillomavirus infection, Human T-cell leukemia virus 1 infection, Herpes simplex virus 1 infection, Epstein-Barr virus infection, Human immunodeficiency virus 1 infection, Coronavirus disease, Proteoglycans in cancer, Asthma, Inflammatory bowel disease, Systemic lupus erythematosus, Rheumatoid arthritis, Allograft rejection, Graft-versus-host disease, Hypertrophic cardiomyopathy, Dilated cardiomyopathy, Lipid and atherosclerosis, Fluid shear stress and atherosclerosis Infliximab 💬 Infliximab [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 95, 96, 97, 98, 107, 162, 164, 223, 269, 270, 271 💬
544 TNF 💬 [66] MAPK signaling pathway, Cytokine-cytokine receptor interaction, Viral protein interaction with cytokine and cytokine receptor, NF-kappa B signaling pathway, Sphingolipid signaling pathway, mTOR signaling pathway, Apoptosis, Necroptosis, TGF-beta signaling pathway, Osteoclast differentiation, Antigen processing and presentation, Toll-like receptor signaling pathway, NOD-like receptor signaling pathway, RIG-I-like receptor signaling pathway, C-type lectin receptor signaling pathway, Hematopoietic cell lineage, Natural killer cell mediated cytotoxicity, IL-17 signaling pathway, T cell receptor signaling pathway, Fc epsilon RI signaling pathway, TNF signaling pathway, Adipocytokine signaling pathway, Type II diabetes mellitus, Insulin resistance, Non-alcoholic fatty liver disease, AGE-RAGE signaling pathway in diabetic complications, Alcoholic liver disease, Type I diabetes mellitus, Alzheimer disease, Amyotrophic lateral sclerosis, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Shigellosis, Salmonella infection, Pertussis, Legionellosis, Yersinia infection, Leishmaniasis, Chagas disease, African trypanosomiasis, Malaria, Toxoplasmosis, Amoebiasis, Tuberculosis, Hepatitis C, Hepatitis B, Human cytomegalovirus infection, Influenza A, Human papillomavirus infection, Human T-cell leukemia virus 1 infection, Herpes simplex virus 1 infection, Epstein-Barr virus infection, Human immunodeficiency virus 1 infection, Coronavirus disease, Proteoglycans in cancer, Asthma, Inflammatory bowel disease, Systemic lupus erythematosus, Rheumatoid arthritis, Allograft rejection, Graft-versus-host disease, Hypertrophic cardiomyopathy, Dilated cardiomyopathy, Lipid and atherosclerosis, Fluid shear stress and atherosclerosis Golimumab 💬 Golimumab [8] 46, 56, 84, 96, 97, 107, 270, 271 💬
545 TNF 💬 [66] MAPK signaling pathway, Cytokine-cytokine receptor interaction, Viral protein interaction with cytokine and cytokine receptor, NF-kappa B signaling pathway, Sphingolipid signaling pathway, mTOR signaling pathway, Apoptosis, Necroptosis, TGF-beta signaling pathway, Osteoclast differentiation, Antigen processing and presentation, Toll-like receptor signaling pathway, NOD-like receptor signaling pathway, RIG-I-like receptor signaling pathway, C-type lectin receptor signaling pathway, Hematopoietic cell lineage, Natural killer cell mediated cytotoxicity, IL-17 signaling pathway, T cell receptor signaling pathway, Fc epsilon RI signaling pathway, TNF signaling pathway, Adipocytokine signaling pathway, Type II diabetes mellitus, Insulin resistance, Non-alcoholic fatty liver disease, AGE-RAGE signaling pathway in diabetic complications, Alcoholic liver disease, Type I diabetes mellitus, Alzheimer disease, Amyotrophic lateral sclerosis, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Shigellosis, Salmonella infection, Pertussis, Legionellosis, Yersinia infection, Leishmaniasis, Chagas disease, African trypanosomiasis, Malaria, Toxoplasmosis, Amoebiasis, Tuberculosis, Hepatitis C, Hepatitis B, Human cytomegalovirus infection, Influenza A, Human papillomavirus infection, Human T-cell leukemia virus 1 infection, Herpes simplex virus 1 infection, Epstein-Barr virus infection, Human immunodeficiency virus 1 infection, Coronavirus disease, Proteoglycans in cancer, Asthma, Inflammatory bowel disease, Systemic lupus erythematosus, Rheumatoid arthritis, Allograft rejection, Graft-versus-host disease, Hypertrophic cardiomyopathy, Dilated cardiomyopathy, Lipid and atherosclerosis, Fluid shear stress and atherosclerosis Adalimumab 💬 Adalimumab [22] 19, 37, 38, 40, 41, 46, 55, 56, 84, 90, 96, 97, 107, 151, 160, 162, 164, 222, 226, 269, 270, 271 💬
546 TNF 💬 [66] MAPK signaling pathway, Cytokine-cytokine receptor interaction, Viral protein interaction with cytokine and cytokine receptor, NF-kappa B signaling pathway, Sphingolipid signaling pathway, mTOR signaling pathway, Apoptosis, Necroptosis, TGF-beta signaling pathway, Osteoclast differentiation, Antigen processing and presentation, Toll-like receptor signaling pathway, NOD-like receptor signaling pathway, RIG-I-like receptor signaling pathway, C-type lectin receptor signaling pathway, Hematopoietic cell lineage, Natural killer cell mediated cytotoxicity, IL-17 signaling pathway, T cell receptor signaling pathway, Fc epsilon RI signaling pathway, TNF signaling pathway, Adipocytokine signaling pathway, Type II diabetes mellitus, Insulin resistance, Non-alcoholic fatty liver disease, AGE-RAGE signaling pathway in diabetic complications, Alcoholic liver disease, Type I diabetes mellitus, Alzheimer disease, Amyotrophic lateral sclerosis, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Shigellosis, Salmonella infection, Pertussis, Legionellosis, Yersinia infection, Leishmaniasis, Chagas disease, African trypanosomiasis, Malaria, Toxoplasmosis, Amoebiasis, Tuberculosis, Hepatitis C, Hepatitis B, Human cytomegalovirus infection, Influenza A, Human papillomavirus infection, Human T-cell leukemia virus 1 infection, Herpes simplex virus 1 infection, Epstein-Barr virus infection, Human immunodeficiency virus 1 infection, Coronavirus disease, Proteoglycans in cancer, Asthma, Inflammatory bowel disease, Systemic lupus erythematosus, Rheumatoid arthritis, Allograft rejection, Graft-versus-host disease, Hypertrophic cardiomyopathy, Dilated cardiomyopathy, Lipid and atherosclerosis, Fluid shear stress and atherosclerosis Thalidomide 💬 Thalidomide [22] 2, 16, 20, 28, 49, 51, 53, 56, 63, 65, 84, 85, 94, 96, 97, 117, 227, 271, 280, 298, 300, 331 💬
547 TNFRSF1A 💬 [35] MAPK signaling pathway, Cytokine-cytokine receptor interaction, Viral protein interaction with cytokine and cytokine receptor, NF-kappa B signaling pathway, Sphingolipid signaling pathway, mTOR signaling pathway, Apoptosis, Apoptosis - multiple species, Necroptosis, Osteoclast differentiation, TNF signaling pathway, Adipocytokine signaling pathway, Insulin resistance, Non-alcoholic fatty liver disease, Alcoholic liver disease, Alzheimer disease, Amyotrophic lateral sclerosis, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Shigellosis, Salmonella infection, Chagas disease, Toxoplasmosis, Tuberculosis, Hepatitis C, Human cytomegalovirus infection, Influenza A, Human papillomavirus infection, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Herpes simplex virus 1 infection, Human immunodeficiency virus 1 infection, Coronavirus disease, Lipid and atherosclerosis, Fluid shear stress and atherosclerosis Balinatunfib 💬 Balinatunfib [2] 96, 97 💬
548 TNFRSF1B 💬 [7] Cytokine-cytokine receptor interaction, Viral protein interaction with cytokine and cytokine receptor, TNF signaling pathway, Adipocytokine signaling pathway, Amyotrophic lateral sclerosis, Pathways of neurodegeneration - multiple diseases, Human immunodeficiency virus 1 infection Balinatunfib 💬 Balinatunfib [2] 96, 97 💬
549 TNFSF15 💬 [1] Cytokine-cytokine receptor interaction Tulisokibart 💬 Tulisokibart [5] 46, 51, 96, 97, 271 💬
550 TNFSF15 💬 [1] Cytokine-cytokine receptor interaction Duvakitug 💬 Duvakitug [2] 96, 97 💬
551 TNFSF15 💬 [1] Cytokine-cytokine receptor interaction Afimkibart 💬 Afimkibart [3] 46, 96, 97 💬
552 TPH1 💬 [3] Tryptophan metabolism, Folate biosynthesis, Serotonergic synapse Telotristat 💬 Telotristat [1] 97 💬
553 TPH1 💬 [3] Tryptophan metabolism, Folate biosynthesis, Serotonergic synapse Telotristat etiprate 💬 Telotristat ethyl [1] 97 💬
554 TPH1 💬 [3] Tryptophan metabolism, Folate biosynthesis, Serotonergic synapse Telotristat ethyl 💬 Telotristat ethyl [1] 97 💬
555 TPH2 💬 [3] Tryptophan metabolism, Folate biosynthesis, Serotonergic synapse Telotristat ethyl 💬 Telotristat ethyl [1] 97 💬
556 TPH2 💬 [3] Tryptophan metabolism, Folate biosynthesis, Serotonergic synapse Telotristat etiprate 💬 Telotristat ethyl [1] 97 💬
557 TPH2 💬 [3] Tryptophan metabolism, Folate biosynthesis, Serotonergic synapse Telotristat 💬 Telotristat [1] 97 💬
558 TUBB 💬 [12] Phagocytosis, IgSF CAM signaling, Gap junction, Motor proteins, Alzheimer disease, Parkinson disease, Amyotrophic lateral sclerosis, Huntington disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection Colchicine 💬 Colchicine [9] 2, 42, 46, 50, 56, 93, 97, 210, 266 💬
559 TUBB1 💬 [12] Phagocytosis, IgSF CAM signaling, Gap junction, Motor proteins, Alzheimer disease, Parkinson disease, Amyotrophic lateral sclerosis, Huntington disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection Colchicine 💬 Colchicine [9] 2, 42, 46, 50, 56, 93, 97, 210, 266 💬
560 TUBB2A 💬 [12] Phagocytosis, IgSF CAM signaling, Gap junction, Motor proteins, Alzheimer disease, Parkinson disease, Amyotrophic lateral sclerosis, Huntington disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection Colchicine 💬 Colchicine [9] 2, 42, 46, 50, 56, 93, 97, 210, 266 💬
561 TUBB2B 💬 [12] Phagocytosis, IgSF CAM signaling, Gap junction, Motor proteins, Alzheimer disease, Parkinson disease, Amyotrophic lateral sclerosis, Huntington disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection Colchicine 💬 Colchicine [9] 2, 42, 46, 50, 56, 93, 97, 210, 266 💬
562 TUBB3 💬 [12] Phagocytosis, IgSF CAM signaling, Gap junction, Motor proteins, Alzheimer disease, Parkinson disease, Amyotrophic lateral sclerosis, Huntington disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection Colchicine 💬 Colchicine [9] 2, 42, 46, 50, 56, 93, 97, 210, 266 💬
563 TUBB4A 💬 [12] Phagocytosis, IgSF CAM signaling, Gap junction, Motor proteins, Alzheimer disease, Parkinson disease, Amyotrophic lateral sclerosis, Huntington disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection Colchicine 💬 Colchicine [9] 2, 42, 46, 50, 56, 93, 97, 210, 266 💬
564 TUBB4B 💬 [12] Phagocytosis, IgSF CAM signaling, Gap junction, Motor proteins, Alzheimer disease, Parkinson disease, Amyotrophic lateral sclerosis, Huntington disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection Colchicine 💬 Colchicine [9] 2, 42, 46, 50, 56, 93, 97, 210, 266 💬
565 TUBB6 💬 [12] Phagocytosis, IgSF CAM signaling, Gap junction, Motor proteins, Alzheimer disease, Parkinson disease, Amyotrophic lateral sclerosis, Huntington disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection Colchicine 💬 Colchicine [9] 2, 42, 46, 50, 56, 93, 97, 210, 266 💬
566 TUBB8 💬 [12] Phagocytosis, IgSF CAM signaling, Gap junction, Motor proteins, Alzheimer disease, Parkinson disease, Amyotrophic lateral sclerosis, Huntington disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection Colchicine 💬 Colchicine [9] 2, 42, 46, 50, 56, 93, 97, 210, 266 💬
567 TYK2 💬 [17] Necroptosis, Osteoclast differentiation, Toll-like receptor signaling pathway, NOD-like receptor signaling pathway, JAK-STAT signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Hepatitis C, Hepatitis B, Measles, Influenza A, Human papillomavirus infection, Kaposi sarcoma-associated herpesvirus infection, Herpes simplex virus 1 infection, Epstein-Barr virus infection, Coronavirus disease Tofacitinib citrate 💬 Tofacitinib [23] 2, 11, 35, 38, 39, 40, 44, 46, 49, 50, 51, 53, 56, 65, 66, 84, 96, 97, 107, 110, 162, 271, 300 💬
568 TYK2 💬 [17] Necroptosis, Osteoclast differentiation, Toll-like receptor signaling pathway, NOD-like receptor signaling pathway, JAK-STAT signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Hepatitis C, Hepatitis B, Measles, Influenza A, Human papillomavirus infection, Kaposi sarcoma-associated herpesvirus infection, Herpes simplex virus 1 infection, Epstein-Barr virus infection, Coronavirus disease Zasocitinib 💬 Zasocitinib [2] 96, 97 💬
569 TYK2 💬 [17] Necroptosis, Osteoclast differentiation, Toll-like receptor signaling pathway, NOD-like receptor signaling pathway, JAK-STAT signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Hepatitis C, Hepatitis B, Measles, Influenza A, Human papillomavirus infection, Kaposi sarcoma-associated herpesvirus infection, Herpes simplex virus 1 infection, Epstein-Barr virus infection, Coronavirus disease Deucravacitinib 💬 Deucravacitinib [10] 36, 37, 40, 49, 53, 84, 96, 97, 160, 269 💬
570 TYK2 💬 [17] Necroptosis, Osteoclast differentiation, Toll-like receptor signaling pathway, NOD-like receptor signaling pathway, JAK-STAT signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Hepatitis C, Hepatitis B, Measles, Influenza A, Human papillomavirus infection, Kaposi sarcoma-associated herpesvirus infection, Herpes simplex virus 1 infection, Epstein-Barr virus infection, Coronavirus disease Brepocitinib 💬 Brepocitinib [5] 49, 50, 84, 96, 97 💬
571 TYK2 💬 [17] Necroptosis, Osteoclast differentiation, Toll-like receptor signaling pathway, NOD-like receptor signaling pathway, JAK-STAT signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Hepatitis C, Hepatitis B, Measles, Influenza A, Human papillomavirus infection, Kaposi sarcoma-associated herpesvirus infection, Herpes simplex virus 1 infection, Epstein-Barr virus infection, Coronavirus disease Filgotinib maleate 💬 Filgotinib [10] 46, 53, 56, 96, 97, 107, 222, 271, 300, 331 💬
572 TYK2 💬 [17] Necroptosis, Osteoclast differentiation, Toll-like receptor signaling pathway, NOD-like receptor signaling pathway, JAK-STAT signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Hepatitis C, Hepatitis B, Measles, Influenza A, Human papillomavirus infection, Kaposi sarcoma-associated herpesvirus infection, Herpes simplex virus 1 infection, Epstein-Barr virus infection, Coronavirus disease Tofacitinib 💬 Tofacitinib [23] 2, 11, 35, 38, 39, 40, 44, 46, 49, 50, 51, 53, 56, 65, 66, 84, 96, 97, 107, 110, 162, 271, 300 💬
573 VDR 💬 [5] Parathyroid hormone synthesis, secretion and action, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Tuberculosis, Chemical carcinogenesis - receptor activation Cholecalciferol 💬 Cholecalciferol [10] 13, 19, 34, 46, 49, 96, 97, 222, 298, 299 💬
574 VDR 💬 [5] Parathyroid hormone synthesis, secretion and action, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Tuberculosis, Chemical carcinogenesis - receptor activation Ergocalciferol 💬 Ergocalciferol [5] 46, 84, 96, 97, 299 💬
575 VKORC1 💬 [1] Ubiquinone and other terpenoid-quinone biosynthesis Warfarin sodium 💬 Warfarin [15] 6, 8, 13, 19, 46, 48, 49, 66, 85, 86, 88, 91, 96, 97, 222 💬
576 VKORC1 💬 [1] Ubiquinone and other terpenoid-quinone biosynthesis Warfarin potassium 💬 Warfarin [15] 6, 8, 13, 19, 46, 48, 49, 66, 85, 86, 88, 91, 96, 97, 222 💬
577 VKORC1 💬 [1] Ubiquinone and other terpenoid-quinone biosynthesis Warfarin 💬 Warfarin [15] 6, 8, 13, 19, 46, 48, 49, 66, 85, 86, 88, 91, 96, 97, 222 💬
578 XDH 💬 [4] Purine metabolism, Caffeine metabolism, Drug metabolism - other enzymes, Peroxisome Allopurinol sodium 💬 Allopurinol [7] 6, 46, 57, 60, 66, 96, 97 💬
579 XDH 💬 [4] Purine metabolism, Caffeine metabolism, Drug metabolism - other enzymes, Peroxisome Febuxostat 💬 Febuxostat [5] 2, 6, 13, 67, 97 💬
580 XDH 💬 [4] Purine metabolism, Caffeine metabolism, Drug metabolism - other enzymes, Peroxisome Febuxostat hydrate 💬 Febuxostat [5] 2, 6, 13, 67, 97 💬
581 XDH 💬 [4] Purine metabolism, Caffeine metabolism, Drug metabolism - other enzymes, Peroxisome Allopurinol 💬 Allopurinol [7] 6, 46, 57, 60, 66, 96, 97 💬