Target Gene/Pathway Pathway / Gene

  

Search results

No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank Disease ID
1 ABL1 💬 [12] ErbB signaling pathway, Ras signaling pathway, Cell cycle, Axon guidance, IgSF CAM signaling, Neurotrophin signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, MicroRNAs in cancer, Chemical carcinogenesis - reactive oxygen species, Chronic myeloid leukemia, Viral myocarditis Bosutinib 💬 Bosutinib [2] 2, 67 💬
2 ABL1 💬 [12] ErbB signaling pathway, Ras signaling pathway, Cell cycle, Axon guidance, IgSF CAM signaling, Neurotrophin signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, MicroRNAs in cancer, Chemical carcinogenesis - reactive oxygen species, Chronic myeloid leukemia, Viral myocarditis Bosutinib hydrate 💬 Bosutinib [2] 2, 67 💬
3 ADORA1 💬 [8] cGMP-PKG signaling pathway, cAMP signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Regulation of lipolysis in adipocytes, Renin secretion, Morphine addiction Caffeine citrate 💬 Caffeine [8] 2, 6, 13, 21, 46, 96, 97, 265 💬
4 ADORA1 💬 [8] cGMP-PKG signaling pathway, cAMP signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Regulation of lipolysis in adipocytes, Renin secretion, Morphine addiction Caffeine 💬 Caffeine [8] 2, 6, 13, 21, 46, 96, 97, 265 💬
5 ADORA2A 💬 [8] Rap1 signaling pathway, Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Vascular smooth muscle contraction, Parkinson disease, Alcoholism Caffeine 💬 Caffeine [8] 2, 6, 13, 21, 46, 96, 97, 265 💬
6 ADORA2A 💬 [8] Rap1 signaling pathway, Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Vascular smooth muscle contraction, Parkinson disease, Alcoholism Caffeine citrate 💬 Caffeine [8] 2, 6, 13, 21, 46, 96, 97, 265 💬
7 ADRA1A 💬 [9] Calcium signaling pathway, cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Salivary secretion Olanzapine 💬 Olanzapine [2] 2, 8 💬
8 ADRA1A 💬 [9] Calcium signaling pathway, cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Salivary secretion Olanzapine pamoate 💬 Olanzapine [2] 2, 8 💬
9 ADRA1B 💬 [8] Calcium signaling pathway, cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Salivary secretion Olanzapine pamoate 💬 Olanzapine [2] 2, 8 💬
10 ADRA1B 💬 [8] Calcium signaling pathway, cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Salivary secretion Olanzapine 💬 Olanzapine [2] 2, 8 💬
11 ADRA1D 💬 [8] Calcium signaling pathway, cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Salivary secretion Olanzapine pamoate 💬 Olanzapine [2] 2, 8 💬
12 ADRA1D 💬 [8] Calcium signaling pathway, cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Salivary secretion Olanzapine 💬 Olanzapine [2] 2, 8 💬
13 ADRA2A 💬 [4] cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling Guanabenz 💬 Guanabenz [2] 2, 13 💬
14 ADRA2A 💬 [4] cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling Guanabenz acetate 💬 Guanabenz [2] 2, 13 💬
15 ADRA2A 💬 [4] cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling Pimozide 💬 Pimozide [1] 2 💬
16 ADRA2A 💬 [4] cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling Dexmedetomidine hydrochloride 💬 Dexmedetomidine [15] 2, 4, 6, 21, 22, 34, 46, 70, 107, 113, 171, 212, 215, 226, 280 💬
17 ADRA2A 💬 [4] cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling Dexmedetomidine 💬 Dexmedetomidine [15] 2, 4, 6, 21, 22, 34, 46, 70, 107, 113, 171, 212, 215, 226, 280 💬
18 ADRA2B 💬 [4] cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling Guanabenz 💬 Guanabenz [2] 2, 13 💬
19 ADRA2B 💬 [4] cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling Guanabenz acetate 💬 Guanabenz [2] 2, 13 💬
20 ADRA2B 💬 [4] cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling Dexmedetomidine 💬 Dexmedetomidine [15] 2, 4, 6, 21, 22, 34, 46, 70, 107, 113, 171, 212, 215, 226, 280 💬
21 ADRA2B 💬 [4] cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling Dexmedetomidine hydrochloride 💬 Dexmedetomidine [15] 2, 4, 6, 21, 22, 34, 46, 70, 107, 113, 171, 212, 215, 226, 280 💬
22 ADRA2C 💬 [4] cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling Guanabenz 💬 Guanabenz [2] 2, 13 💬
23 ADRA2C 💬 [4] cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling Guanabenz acetate 💬 Guanabenz [2] 2, 13 💬
24 ADRA2C 💬 [4] cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling Dexmedetomidine 💬 Dexmedetomidine [15] 2, 4, 6, 21, 22, 34, 46, 70, 107, 113, 171, 212, 215, 226, 280 💬
25 ADRA2C 💬 [4] cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling Dexmedetomidine hydrochloride 💬 Dexmedetomidine [15] 2, 4, 6, 21, 22, 34, 46, 70, 107, 113, 171, 212, 215, 226, 280 💬
26 ADRB2 💬 [11] Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Adrenergic signaling in cardiomyocytes, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Chemical carcinogenesis - receptor activation Clenbuterol 💬 Clenbuterol [6] 1, 2, 6, 57, 113, 256 💬
27 ADRB2 💬 [11] Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Adrenergic signaling in cardiomyocytes, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Chemical carcinogenesis - receptor activation Clenbuterol hydrochloride 💬 Clenbuterol [6] 1, 2, 6, 57, 113, 256 💬
28 ALK 💬 [3] Pathways in cancer, Non-small cell lung cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer Crizotinib 💬 Crizotinib [2] 2, 34 💬
29 ALOX15 💬 [6] Arachidonic acid metabolism, Linoleic acid metabolism, Efferocytosis, Ferroptosis, Necroptosis, Serotonergic synapse Utreloxastat 💬 Utreloxastat [1] 2 💬
30 AR 💬 [4] Oocyte meiosis, Pathways in cancer, Chemical carcinogenesis - receptor activation, Prostate cancer Testosterone 💬 Testosterone [9] 1, 2, 3, 13, 60, 76, 78, 113, 265 💬
31 ATP1A1 💬 [19] cGMP-PKG signaling pathway, cAMP signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Cytoskeleton in muscle cells, Insulin secretion, Thyroid hormone synthesis, Thyroid hormone signaling pathway, Aldosterone synthesis and secretion, Aldosterone-regulated sodium reabsorption, Endocrine and other factor-regulated calcium reabsorption, Proximal tubule bicarbonate reclamation, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Carbohydrate digestion and absorption, Protein digestion and absorption, Bile secretion, Mineral absorption Digoxin 💬 Digoxin [7] 2, 8, 46, 57, 65, 67, 210 💬
32 ATP1A2 💬 [19] cGMP-PKG signaling pathway, cAMP signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Cytoskeleton in muscle cells, Insulin secretion, Thyroid hormone synthesis, Thyroid hormone signaling pathway, Aldosterone synthesis and secretion, Aldosterone-regulated sodium reabsorption, Endocrine and other factor-regulated calcium reabsorption, Proximal tubule bicarbonate reclamation, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Carbohydrate digestion and absorption, Protein digestion and absorption, Bile secretion, Mineral absorption Digoxin 💬 Digoxin [7] 2, 8, 46, 57, 65, 67, 210 💬
33 ATP1A3 💬 [19] cGMP-PKG signaling pathway, cAMP signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Cytoskeleton in muscle cells, Insulin secretion, Thyroid hormone synthesis, Thyroid hormone signaling pathway, Aldosterone synthesis and secretion, Aldosterone-regulated sodium reabsorption, Endocrine and other factor-regulated calcium reabsorption, Proximal tubule bicarbonate reclamation, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Carbohydrate digestion and absorption, Protein digestion and absorption, Bile secretion, Mineral absorption Digoxin 💬 Digoxin [7] 2, 8, 46, 57, 65, 67, 210 💬
34 ATP1A4 💬 [19] cGMP-PKG signaling pathway, cAMP signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Cytoskeleton in muscle cells, Insulin secretion, Thyroid hormone synthesis, Thyroid hormone signaling pathway, Aldosterone synthesis and secretion, Aldosterone-regulated sodium reabsorption, Endocrine and other factor-regulated calcium reabsorption, Proximal tubule bicarbonate reclamation, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Carbohydrate digestion and absorption, Protein digestion and absorption, Bile secretion, Mineral absorption Digoxin 💬 Digoxin [7] 2, 8, 46, 57, 65, 67, 210 💬
35 ATP4A 💬 [3] Oxidative phosphorylation, Collecting duct acid secretion, Gastric acid secretion Rabeprazole sodium 💬 Rabeprazole [3] 2, 6, 51 💬
36 ATP4A 💬 [3] Oxidative phosphorylation, Collecting duct acid secretion, Gastric acid secretion Rabeprazole 💬 Rabeprazole [3] 2, 6, 51 💬
37 ATP4B 💬 [3] Oxidative phosphorylation, Collecting duct acid secretion, Gastric acid secretion Rabeprazole sodium 💬 Rabeprazole [3] 2, 6, 51 💬
38 ATP4B 💬 [3] Oxidative phosphorylation, Collecting duct acid secretion, Gastric acid secretion Rabeprazole 💬 Rabeprazole [3] 2, 6, 51 💬
39 C3 💬 [18] Neuroactive ligand-receptor interaction, Phagocytosis, Integrin signaling, Complement and coagulation cascades, Neutrophil extracellular trap formation, Alcoholic liver disease, Shigellosis, Pertussis, Legionellosis, Leishmaniasis, Chagas disease, Staphylococcus aureus infection, Tuberculosis, Kaposi sarcoma-associated herpesvirus infection, Herpes simplex virus 1 infection, Coronavirus disease, Viral carcinogenesis, Systemic lupus erythematosus Pegcetacoplan 💬 Pegcetacoplan [4] 2, 61, 62, 223 💬
40 C5 💬 [11] Neuroactive ligand-receptor interaction, Complement and coagulation cascades, Neutrophil extracellular trap formation, Regulation of actin cytoskeleton, Alcoholic liver disease, Prion disease, Pertussis, Staphylococcus aureus infection, Herpes simplex virus 1 infection, Coronavirus disease, Systemic lupus erythematosus Ravulizumab 💬 Ravulizumab [8] 2, 11, 13, 50, 62, 66, 109, 224 💬
41 C5 💬 [11] Neuroactive ligand-receptor interaction, Complement and coagulation cascades, Neutrophil extracellular trap formation, Regulation of actin cytoskeleton, Alcoholic liver disease, Prion disease, Pertussis, Staphylococcus aureus infection, Herpes simplex virus 1 infection, Coronavirus disease, Systemic lupus erythematosus Zilucoplan sodium 💬 Zilucoplan [3] 2, 11, 62 💬
42 C5 💬 [11] Neuroactive ligand-receptor interaction, Complement and coagulation cascades, Neutrophil extracellular trap formation, Regulation of actin cytoskeleton, Alcoholic liver disease, Prion disease, Pertussis, Staphylococcus aureus infection, Herpes simplex virus 1 infection, Coronavirus disease, Systemic lupus erythematosus Zilucoplan 💬 Zilucoplan [3] 2, 11, 62 💬
43 CD80 💬 [12] Virion - Adenovirus, Cell adhesion molecule (CAM) interaction, IgSF CAM signaling, Toll-like receptor signaling pathway, Intestinal immune network for IgA production, Type I diabetes mellitus, Autoimmune thyroid disease, Systemic lupus erythematosus, Rheumatoid arthritis, Allograft rejection, Graft-versus-host disease, Viral myocarditis Abatacept 💬 Abatacept [28] 2, 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 223, 271, 284, 285, 300 💬
44 CD86 💬 [14] Virion - Adenovirus, Cell adhesion molecule (CAM) interaction, IgSF CAM signaling, Toll-like receptor signaling pathway, Intestinal immune network for IgA production, Type I diabetes mellitus, Kaposi sarcoma-associated herpesvirus infection, Transcriptional misregulation in cancer, Autoimmune thyroid disease, Systemic lupus erythematosus, Rheumatoid arthritis, Allograft rejection, Graft-versus-host disease, Viral myocarditis Abatacept 💬 Abatacept [28] 2, 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 223, 271, 284, 285, 300 💬
45 CHRM1 💬 [9] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, PI3K-Akt signaling pathway, Cholinergic synapse, Regulation of actin cytoskeleton, Alzheimer disease, Pathways of neurodegeneration - multiple diseases Scopolamine 💬 Scopolamine [1] 2 💬
46 CHRM1 💬 [9] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, PI3K-Akt signaling pathway, Cholinergic synapse, Regulation of actin cytoskeleton, Alzheimer disease, Pathways of neurodegeneration - multiple diseases Atropine sulfate 💬 Atropine [1] 2 💬
47 CHRM1 💬 [9] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, PI3K-Akt signaling pathway, Cholinergic synapse, Regulation of actin cytoskeleton, Alzheimer disease, Pathways of neurodegeneration - multiple diseases Scopolamine hydrobromide 💬 Scopolamine [1] 2 💬
48 CHRM1 💬 [9] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, PI3K-Akt signaling pathway, Cholinergic synapse, Regulation of actin cytoskeleton, Alzheimer disease, Pathways of neurodegeneration - multiple diseases Atropine 💬 Atropine [1] 2 💬
49 CHRM2 💬 [7] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, PI3K-Akt signaling pathway, Cholinergic synapse, Regulation of actin cytoskeleton Atropine sulfate 💬 Atropine [1] 2 💬
50 CHRM2 💬 [7] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, PI3K-Akt signaling pathway, Cholinergic synapse, Regulation of actin cytoskeleton Scopolamine hydrobromide 💬 Scopolamine [1] 2 💬
51 CHRM2 💬 [7] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, PI3K-Akt signaling pathway, Cholinergic synapse, Regulation of actin cytoskeleton Atropine 💬 Atropine [1] 2 💬
52 CHRM2 💬 [7] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, PI3K-Akt signaling pathway, Cholinergic synapse, Regulation of actin cytoskeleton Scopolamine 💬 Scopolamine [1] 2 💬
53 CHRM3 💬 [12] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cholinergic synapse, Taste transduction, Regulation of actin cytoskeleton, Insulin secretion, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Alzheimer disease, Pathways of neurodegeneration - multiple diseases Scopolamine hydrobromide 💬 Scopolamine [1] 2 💬
54 CHRM3 💬 [12] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cholinergic synapse, Taste transduction, Regulation of actin cytoskeleton, Insulin secretion, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Alzheimer disease, Pathways of neurodegeneration - multiple diseases Scopolamine 💬 Scopolamine [1] 2 💬
55 CHRM3 💬 [12] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cholinergic synapse, Taste transduction, Regulation of actin cytoskeleton, Insulin secretion, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Alzheimer disease, Pathways of neurodegeneration - multiple diseases Atropine 💬 Atropine [1] 2 💬
56 CHRM3 💬 [12] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cholinergic synapse, Taste transduction, Regulation of actin cytoskeleton, Insulin secretion, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Alzheimer disease, Pathways of neurodegeneration - multiple diseases Darifenacin hydrobromide 💬 Darifenacin [4] 2, 6, 13, 26 💬
57 CHRM3 💬 [12] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cholinergic synapse, Taste transduction, Regulation of actin cytoskeleton, Insulin secretion, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Alzheimer disease, Pathways of neurodegeneration - multiple diseases Atropine sulfate 💬 Atropine [1] 2 💬
58 CHRM3 💬 [12] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cholinergic synapse, Taste transduction, Regulation of actin cytoskeleton, Insulin secretion, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Alzheimer disease, Pathways of neurodegeneration - multiple diseases Darifenacin 💬 Darifenacin [4] 2, 6, 13, 26 💬
59 CHRM4 💬 [4] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cholinergic synapse, Regulation of actin cytoskeleton Scopolamine 💬 Scopolamine [1] 2 💬
60 CHRM4 💬 [4] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cholinergic synapse, Regulation of actin cytoskeleton Scopolamine hydrobromide 💬 Scopolamine [1] 2 💬
61 CHRM4 💬 [4] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cholinergic synapse, Regulation of actin cytoskeleton Atropine sulfate 💬 Atropine [1] 2 💬
62 CHRM4 💬 [4] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cholinergic synapse, Regulation of actin cytoskeleton Atropine 💬 Atropine [1] 2 💬
63 CHRM5 💬 [7] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cholinergic synapse, Regulation of actin cytoskeleton, Alzheimer disease, Pathways of neurodegeneration - multiple diseases Scopolamine hydrobromide 💬 Scopolamine [1] 2 💬
64 CHRM5 💬 [7] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cholinergic synapse, Regulation of actin cytoskeleton, Alzheimer disease, Pathways of neurodegeneration - multiple diseases Scopolamine 💬 Scopolamine [1] 2 💬
65 CHRM5 💬 [7] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cholinergic synapse, Regulation of actin cytoskeleton, Alzheimer disease, Pathways of neurodegeneration - multiple diseases Atropine sulfate 💬 Atropine [1] 2 💬
66 CHRM5 💬 [7] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cholinergic synapse, Regulation of actin cytoskeleton, Alzheimer disease, Pathways of neurodegeneration - multiple diseases Atropine 💬 Atropine [1] 2 💬
67 CNR1 💬 [4] Rap1 signaling pathway, Neuroactive ligand-receptor interaction, Thermogenesis, Retrograde endocannabinoid signaling Dronabinol 💬 Dronabinol [5] 2, 13, 46, 271, 298 💬
68 CNR2 💬 [1] Neuroactive ligand-receptor interaction Dronabinol 💬 Dronabinol [5] 2, 13, 46, 271, 298 💬
69 CSF3R 💬 [5] Cytokine-cytokine receptor interaction, PI3K-Akt signaling pathway, JAK-STAT signaling pathway, Hematopoietic cell lineage, Pathways in cancer Filgrastim 💬 Filgrastim [30] 2, 6, 13, 25, 26, 28, 34, 35, 38, 40, 41, 42, 45, 46, 47, 49, 51, 60, 62, 63, 65, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬
70 CSF3R 💬 [5] Cytokine-cytokine receptor interaction, PI3K-Akt signaling pathway, JAK-STAT signaling pathway, Hematopoietic cell lineage, Pathways in cancer Lenograstim 💬 Lenograstim [8] 2, 13, 16, 18, 19, 57, 65, 97 💬
71 CYSLTR1 💬 [2] Calcium signaling pathway, Neuroactive ligand-receptor interaction Ibudilast 💬 Ibudilast [2] 2, 13 💬
72 DRD1 💬 [12] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Amphetamine addiction, Morphine addiction, Alcoholism Dexpramipexole dihydrochloride 💬 Dexpramipexole [1] 2 💬
73 DRD1 💬 [12] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Amphetamine addiction, Morphine addiction, Alcoholism Dexpramipexole 💬 Dexpramipexole [1] 2 💬
74 DRD2 💬 [10] Rap1 signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Alcoholism Pramipexole 💬 Pramipexole [4] 2, 6, 20, 74 💬
75 DRD2 💬 [10] Rap1 signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Alcoholism Dexpramipexole 💬 Dexpramipexole [1] 2 💬
76 DRD2 💬 [10] Rap1 signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Alcoholism Pridopidine 💬 Pridopidine [3] 2, 6, 8 💬
77 DRD2 💬 [10] Rap1 signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Alcoholism Pramipexole dihydrochloride 💬 Pramipexole [4] 2, 6, 20, 74 💬
78 DRD2 💬 [10] Rap1 signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Alcoholism Pimozide 💬 Pimozide [1] 2 💬
79 DRD2 💬 [10] Rap1 signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Alcoholism Pridopidine hydrochloride 💬 Pridopidine [3] 2, 6, 8 💬
80 DRD2 💬 [10] Rap1 signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Alcoholism Olanzapine 💬 Olanzapine [2] 2, 8 💬
81 DRD2 💬 [10] Rap1 signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Alcoholism Olanzapine pamoate 💬 Olanzapine [2] 2, 8 💬
82 DRD2 💬 [10] Rap1 signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Alcoholism Dexpramipexole dihydrochloride 💬 Dexpramipexole [1] 2 💬
83 DRD3 💬 [4] Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Dopaminergic synapse Olanzapine pamoate 💬 Olanzapine [2] 2, 8 💬
84 DRD3 💬 [4] Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Dopaminergic synapse Pramipexole 💬 Pramipexole [4] 2, 6, 20, 74 💬
85 DRD3 💬 [4] Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Dopaminergic synapse Dexpramipexole 💬 Dexpramipexole [1] 2 💬
86 DRD3 💬 [4] Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Dopaminergic synapse Dexpramipexole dihydrochloride 💬 Dexpramipexole [1] 2 💬
87 DRD3 💬 [4] Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Dopaminergic synapse Olanzapine 💬 Olanzapine [2] 2, 8 💬
88 DRD3 💬 [4] Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Dopaminergic synapse Pramipexole dihydrochloride 💬 Pramipexole [4] 2, 6, 20, 74 💬
89 DRD4 💬 [4] Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Dopaminergic synapse Olanzapine pamoate 💬 Olanzapine [2] 2, 8 💬
90 DRD4 💬 [4] Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Dopaminergic synapse Olanzapine 💬 Olanzapine [2] 2, 8 💬
91 DRD4 💬 [4] Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Dopaminergic synapse Pramipexole dihydrochloride 💬 Pramipexole [4] 2, 6, 20, 74 💬
92 DRD4 💬 [4] Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Dopaminergic synapse Pramipexole 💬 Pramipexole [4] 2, 6, 20, 74 💬
93 DRD4 💬 [4] Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Dopaminergic synapse Dexpramipexole dihydrochloride 💬 Dexpramipexole [1] 2 💬
94 DRD4 💬 [4] Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Dopaminergic synapse Dexpramipexole 💬 Dexpramipexole [1] 2 💬
95 DRD5 💬 [6] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Dopaminergic synapse Dexpramipexole dihydrochloride 💬 Dexpramipexole [1] 2 💬
96 DRD5 💬 [6] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Dopaminergic synapse Dexpramipexole 💬 Dexpramipexole [1] 2 💬
97 EIF2B1 💬 [2] Integrated stress response (ISR) signaling pathway, Herpes simplex virus 1 infection Fosigotifator 💬 Fosigotifator [2] 2, 308 💬
98 EIF2B2 💬 [2] Integrated stress response (ISR) signaling pathway, Herpes simplex virus 1 infection Fosigotifator 💬 Fosigotifator [2] 2, 308 💬
99 EIF2B3 💬 [2] Integrated stress response (ISR) signaling pathway, Herpes simplex virus 1 infection Fosigotifator 💬 Fosigotifator [2] 2, 308 💬
100 EIF2B4 💬 [2] Integrated stress response (ISR) signaling pathway, Herpes simplex virus 1 infection Fosigotifator 💬 Fosigotifator [2] 2, 308 💬
101 EIF2B5 💬 [2] Integrated stress response (ISR) signaling pathway, Herpes simplex virus 1 infection Fosigotifator 💬 Fosigotifator [2] 2, 308 💬
102 EPOR 💬 [7] Cytokine-cytokine receptor interaction, Hormone signaling, Efferocytosis, PI3K-Akt signaling pathway, JAK-STAT signaling pathway, Hematopoietic cell lineage, Pathways in cancer Epoetin epsilon 💬 Erythropoietin [11] 2, 6, 13, 18, 22, 47, 61, 63, 70, 95, 96 💬
103 EPOR 💬 [7] Cytokine-cytokine receptor interaction, Hormone signaling, Efferocytosis, PI3K-Akt signaling pathway, JAK-STAT signaling pathway, Hematopoietic cell lineage, Pathways in cancer Epoetin alfa 💬 Erythropoietin [11] 2, 6, 13, 18, 22, 47, 61, 63, 70, 95, 96 💬
104 EPOR 💬 [7] Cytokine-cytokine receptor interaction, Hormone signaling, Efferocytosis, PI3K-Akt signaling pathway, JAK-STAT signaling pathway, Hematopoietic cell lineage, Pathways in cancer Epoetin zeta 💬 Erythropoietin [11] 2, 6, 13, 18, 22, 47, 61, 63, 70, 95, 96 💬
105 EPOR 💬 [7] Cytokine-cytokine receptor interaction, Hormone signaling, Efferocytosis, PI3K-Akt signaling pathway, JAK-STAT signaling pathway, Hematopoietic cell lineage, Pathways in cancer Epoetin theta 💬 Erythropoietin [11] 2, 6, 13, 18, 22, 47, 61, 63, 70, 95, 96 💬
106 ESR1 💬 [9] Hormone signaling, Estrogen signaling pathway, Prolactin signaling pathway, Thyroid hormone signaling pathway, Endocrine and other factor-regulated calcium reabsorption, Pathways in cancer, Proteoglycans in cancer, Chemical carcinogenesis - receptor activation, Breast cancer Tamoxifen citrate 💬 Tamoxifen [6] 2, 65, 86, 113, 227, 299 💬
107 ESR1 💬 [9] Hormone signaling, Estrogen signaling pathway, Prolactin signaling pathway, Thyroid hormone signaling pathway, Endocrine and other factor-regulated calcium reabsorption, Pathways in cancer, Proteoglycans in cancer, Chemical carcinogenesis - receptor activation, Breast cancer Tamoxifen 💬 Tamoxifen [6] 2, 65, 86, 113, 227, 299 💬
108 ESR2 💬 [7] Hormone signaling, Estrogen signaling pathway, Prolactin signaling pathway, GnRH secretion, Pathways in cancer, Chemical carcinogenesis - receptor activation, Breast cancer Tamoxifen citrate 💬 Tamoxifen [6] 2, 65, 86, 113, 227, 299 💬
109 ESR2 💬 [7] Hormone signaling, Estrogen signaling pathway, Prolactin signaling pathway, GnRH secretion, Pathways in cancer, Chemical carcinogenesis - receptor activation, Breast cancer Tamoxifen 💬 Tamoxifen [6] 2, 65, 86, 113, 227, 299 💬
110 GABBR1 💬 [8] cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, GABAergic synapse, Taste transduction, Estrogen signaling pathway, GnRH secretion, Morphine addiction Baclofen 💬 Baclofen [8] 2, 10, 13, 18, 65, 70, 149, 206 💬
111 GABBR2 💬 [8] cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, GABAergic synapse, Taste transduction, Estrogen signaling pathway, GnRH secretion, Morphine addiction Baclofen 💬 Baclofen [8] 2, 10, 13, 18, 65, 70, 149, 206 💬
112 GABRA1 💬 [8] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Midazolam hydrochloride 💬 Midazolam [14] 2, 3, 6, 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬
113 GABRA1 💬 [8] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Midazolam maleate 💬 Midazolam [14] 2, 3, 6, 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬
114 GABRA1 💬 [8] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Midazolam 💬 Midazolam [14] 2, 3, 6, 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬
115 GABRA2 💬 [8] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Midazolam maleate 💬 Midazolam [14] 2, 3, 6, 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬
116 GABRA2 💬 [8] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Midazolam hydrochloride 💬 Midazolam [14] 2, 3, 6, 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬
117 GABRA2 💬 [8] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Midazolam 💬 Midazolam [14] 2, 3, 6, 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬
118 GABRA3 💬 [8] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Midazolam maleate 💬 Midazolam [14] 2, 3, 6, 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬
119 GABRA3 💬 [8] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Midazolam hydrochloride 💬 Midazolam [14] 2, 3, 6, 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬
120 GABRA3 💬 [8] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Midazolam 💬 Midazolam [14] 2, 3, 6, 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬
121 GABRA4 💬 [8] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Midazolam maleate 💬 Midazolam [14] 2, 3, 6, 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬
122 GABRA4 💬 [8] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Midazolam 💬 Midazolam [14] 2, 3, 6, 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬
123 GABRA4 💬 [8] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Midazolam hydrochloride 💬 Midazolam [14] 2, 3, 6, 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬
124 GABRA5 💬 [8] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Midazolam hydrochloride 💬 Midazolam [14] 2, 3, 6, 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬
125 GABRA5 💬 [8] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Midazolam 💬 Midazolam [14] 2, 3, 6, 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬
126 GABRA5 💬 [8] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Midazolam maleate 💬 Midazolam [14] 2, 3, 6, 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬
127 GABRA6 💬 [8] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Midazolam 💬 Midazolam [14] 2, 3, 6, 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬
128 GABRA6 💬 [8] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Midazolam maleate 💬 Midazolam [14] 2, 3, 6, 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬
129 GABRA6 💬 [8] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Midazolam hydrochloride 💬 Midazolam [14] 2, 3, 6, 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬
130 GABRB1 💬 [8] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, Serotonergic synapse, GABAergic synapse, Morphine addiction, Nicotine addiction Midazolam 💬 Midazolam [14] 2, 3, 6, 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬
131 GABRB1 💬 [8] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, Serotonergic synapse, GABAergic synapse, Morphine addiction, Nicotine addiction Midazolam hydrochloride 💬 Midazolam [14] 2, 3, 6, 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬
132 GABRB1 💬 [8] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, Serotonergic synapse, GABAergic synapse, Morphine addiction, Nicotine addiction Midazolam maleate 💬 Midazolam [14] 2, 3, 6, 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬
133 GABRB2 💬 [8] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, Serotonergic synapse, GABAergic synapse, Morphine addiction, Nicotine addiction Midazolam hydrochloride 💬 Midazolam [14] 2, 3, 6, 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬
134 GABRB2 💬 [8] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, Serotonergic synapse, GABAergic synapse, Morphine addiction, Nicotine addiction Midazolam maleate 💬 Midazolam [14] 2, 3, 6, 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬
135 GABRB2 💬 [8] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, Serotonergic synapse, GABAergic synapse, Morphine addiction, Nicotine addiction Midazolam 💬 Midazolam [14] 2, 3, 6, 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬
136 GABRB3 💬 [8] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, Serotonergic synapse, GABAergic synapse, Morphine addiction, Nicotine addiction Midazolam maleate 💬 Midazolam [14] 2, 3, 6, 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬
137 GABRB3 💬 [8] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, Serotonergic synapse, GABAergic synapse, Morphine addiction, Nicotine addiction Midazolam hydrochloride 💬 Midazolam [14] 2, 3, 6, 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬
138 GABRB3 💬 [8] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, Serotonergic synapse, GABAergic synapse, Morphine addiction, Nicotine addiction Midazolam 💬 Midazolam [14] 2, 3, 6, 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬
139 GABRD 💬 [7] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Midazolam maleate 💬 Midazolam [14] 2, 3, 6, 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬
140 GABRD 💬 [7] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Midazolam hydrochloride 💬 Midazolam [14] 2, 3, 6, 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬
141 GABRD 💬 [7] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Midazolam 💬 Midazolam [14] 2, 3, 6, 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬
142 GABRE 💬 [7] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Midazolam maleate 💬 Midazolam [14] 2, 3, 6, 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬
143 GABRE 💬 [7] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Midazolam hydrochloride 💬 Midazolam [14] 2, 3, 6, 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬
144 GABRE 💬 [7] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Midazolam 💬 Midazolam [14] 2, 3, 6, 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬
145 GABRG1 💬 [7] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Midazolam 💬 Midazolam [14] 2, 3, 6, 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬
146 GABRG1 💬 [7] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Midazolam hydrochloride 💬 Midazolam [14] 2, 3, 6, 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬
147 GABRG1 💬 [7] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Midazolam maleate 💬 Midazolam [14] 2, 3, 6, 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬
148 GABRG2 💬 [7] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Midazolam hydrochloride 💬 Midazolam [14] 2, 3, 6, 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬
149 GABRG2 💬 [7] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Midazolam maleate 💬 Midazolam [14] 2, 3, 6, 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬
150 GABRG2 💬 [7] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Midazolam 💬 Midazolam [14] 2, 3, 6, 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬
151 GABRG3 💬 [7] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Midazolam 💬 Midazolam [14] 2, 3, 6, 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬
152 GABRG3 💬 [7] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Midazolam maleate 💬 Midazolam [14] 2, 3, 6, 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬
153 GABRG3 💬 [7] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Midazolam hydrochloride 💬 Midazolam [14] 2, 3, 6, 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬
154 GABRP 💬 [7] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Midazolam hydrochloride 💬 Midazolam [14] 2, 3, 6, 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬
155 GABRP 💬 [7] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Midazolam 💬 Midazolam [14] 2, 3, 6, 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬
156 GABRP 💬 [7] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Midazolam maleate 💬 Midazolam [14] 2, 3, 6, 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬
157 GABRQ 💬 [7] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Midazolam 💬 Midazolam [14] 2, 3, 6, 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬
158 GABRQ 💬 [7] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Midazolam maleate 💬 Midazolam [14] 2, 3, 6, 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬
159 GABRQ 💬 [7] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cadherin signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Midazolam hydrochloride 💬 Midazolam [14] 2, 3, 6, 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬
160 GNRHR 💬 [3] Neuroactive ligand-receptor interaction, Hormone signaling, GnRH signaling pathway Leuprolide 💬 Leuprolide [5] 1, 2, 3, 51, 76 💬
161 GNRHR 💬 [3] Neuroactive ligand-receptor interaction, Hormone signaling, GnRH signaling pathway Leuprolide acetate 💬 Leuprolide [5] 1, 2, 3, 51, 76 💬
162 GNRHR 💬 [3] Neuroactive ligand-receptor interaction, Hormone signaling, GnRH signaling pathway Leuprolide mesylate 💬 Leuprolide [5] 1, 2, 3, 51, 76 💬
163 GRIA1 💬 [15] cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Retrograde endocannabinoid signaling, Glutamatergic synapse, Dopaminergic synapse, Long-term depression, Amyotrophic lateral sclerosis, Huntington disease, Spinocerebellar ataxia, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Nicotine addiction Talampanel 💬 Talampanel [2] 2, 6 💬
164 GRIA1 💬 [15] cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Retrograde endocannabinoid signaling, Glutamatergic synapse, Dopaminergic synapse, Long-term depression, Amyotrophic lateral sclerosis, Huntington disease, Spinocerebellar ataxia, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Nicotine addiction Riluzole 💬 Riluzole [9] 2, 3, 5, 8, 13, 17, 18, 203, 206 💬
165 GRIA1 💬 [15] cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Retrograde endocannabinoid signaling, Glutamatergic synapse, Dopaminergic synapse, Long-term depression, Amyotrophic lateral sclerosis, Huntington disease, Spinocerebellar ataxia, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Nicotine addiction Perampanel hydrate 💬 Perampanel [3] 2, 6, 144 💬
166 GRIA1 💬 [15] cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Retrograde endocannabinoid signaling, Glutamatergic synapse, Dopaminergic synapse, Long-term depression, Amyotrophic lateral sclerosis, Huntington disease, Spinocerebellar ataxia, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Nicotine addiction Perampanel 💬 Perampanel [3] 2, 6, 144 💬
167 GRIA2 💬 [16] cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Retrograde endocannabinoid signaling, Glutamatergic synapse, Dopaminergic synapse, Long-term depression, Amyotrophic lateral sclerosis, Huntington disease, Spinocerebellar ataxia, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction Talampanel 💬 Talampanel [2] 2, 6 💬
168 GRIA2 💬 [16] cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Retrograde endocannabinoid signaling, Glutamatergic synapse, Dopaminergic synapse, Long-term depression, Amyotrophic lateral sclerosis, Huntington disease, Spinocerebellar ataxia, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction Perampanel hydrate 💬 Perampanel [3] 2, 6, 144 💬
169 GRIA2 💬 [16] cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Retrograde endocannabinoid signaling, Glutamatergic synapse, Dopaminergic synapse, Long-term depression, Amyotrophic lateral sclerosis, Huntington disease, Spinocerebellar ataxia, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction Perampanel 💬 Perampanel [3] 2, 6, 144 💬
170 GRIA2 💬 [16] cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Retrograde endocannabinoid signaling, Glutamatergic synapse, Dopaminergic synapse, Long-term depression, Amyotrophic lateral sclerosis, Huntington disease, Spinocerebellar ataxia, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction Riluzole 💬 Riluzole [9] 2, 3, 5, 8, 13, 17, 18, 203, 206 💬
171 GRIA3 💬 [14] cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Retrograde endocannabinoid signaling, Glutamatergic synapse, Dopaminergic synapse, Long-term depression, Huntington disease, Spinocerebellar ataxia, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Nicotine addiction, Transcriptional misregulation in cancer Talampanel 💬 Talampanel [2] 2, 6 💬
172 GRIA3 💬 [14] cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Retrograde endocannabinoid signaling, Glutamatergic synapse, Dopaminergic synapse, Long-term depression, Huntington disease, Spinocerebellar ataxia, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Nicotine addiction, Transcriptional misregulation in cancer Perampanel hydrate 💬 Perampanel [3] 2, 6, 144 💬
173 GRIA3 💬 [14] cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Retrograde endocannabinoid signaling, Glutamatergic synapse, Dopaminergic synapse, Long-term depression, Huntington disease, Spinocerebellar ataxia, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Nicotine addiction, Transcriptional misregulation in cancer Riluzole 💬 Riluzole [9] 2, 3, 5, 8, 13, 17, 18, 203, 206 💬
174 GRIA3 💬 [14] cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Retrograde endocannabinoid signaling, Glutamatergic synapse, Dopaminergic synapse, Long-term depression, Huntington disease, Spinocerebellar ataxia, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Nicotine addiction, Transcriptional misregulation in cancer Perampanel 💬 Perampanel [3] 2, 6, 144 💬
175 GRIA4 💬 [11] cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Retrograde endocannabinoid signaling, Glutamatergic synapse, Dopaminergic synapse, Huntington disease, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Nicotine addiction Talampanel 💬 Talampanel [2] 2, 6 💬
176 GRIA4 💬 [11] cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Retrograde endocannabinoid signaling, Glutamatergic synapse, Dopaminergic synapse, Huntington disease, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Nicotine addiction Riluzole 💬 Riluzole [9] 2, 3, 5, 8, 13, 17, 18, 203, 206 💬
177 GRIA4 💬 [11] cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Retrograde endocannabinoid signaling, Glutamatergic synapse, Dopaminergic synapse, Huntington disease, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Nicotine addiction Perampanel 💬 Perampanel [3] 2, 6, 144 💬
178 GRIA4 💬 [11] cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Retrograde endocannabinoid signaling, Glutamatergic synapse, Dopaminergic synapse, Huntington disease, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Nicotine addiction Perampanel hydrate 💬 Perampanel [3] 2, 6, 144 💬
179 GRIK1 💬 [3] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Glutamatergic synapse Riluzole 💬 Riluzole [9] 2, 3, 5, 8, 13, 17, 18, 203, 206 💬
180 GRIK2 💬 [3] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Glutamatergic synapse Riluzole 💬 Riluzole [9] 2, 3, 5, 8, 13, 17, 18, 203, 206 💬
181 GRIK3 💬 [3] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Glutamatergic synapse Riluzole 💬 Riluzole [9] 2, 3, 5, 8, 13, 17, 18, 203, 206 💬
182 GRIK4 💬 [3] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Glutamatergic synapse Riluzole 💬 Riluzole [9] 2, 3, 5, 8, 13, 17, 18, 203, 206 💬
183 GRIK5 💬 [3] Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Glutamatergic synapse Riluzole 💬 Riluzole [9] 2, 3, 5, 8, 13, 17, 18, 203, 206 💬
184 GRIN1 💬 [19] Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Huntington disease, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism Memantine hydrochloride 💬 Memantine [8] 2, 6, 8, 13, 49, 127, 205, 206 💬
185 GRIN1 💬 [19] Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Huntington disease, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism Dextromethorphan polistirex 💬 Dextromethorphan [10] 2, 6, 8, 13, 21, 46, 85, 96, 97, 156 💬
186 GRIN1 💬 [19] Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Huntington disease, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism Esketamine hydrochloride 💬 Esketamine [7] 2, 4, 6, 70, 96, 97, 156 💬
187 GRIN1 💬 [19] Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Huntington disease, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism Esketamine 💬 Esketamine [7] 2, 4, 6, 70, 96, 97, 156 💬
188 GRIN1 💬 [19] Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Huntington disease, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism Memantine 💬 Memantine [8] 2, 6, 8, 13, 49, 127, 205, 206 💬
189 GRIN1 💬 [19] Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Huntington disease, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism Dextromethorphan hydrobromide 💬 Dextromethorphan [10] 2, 6, 8, 13, 21, 46, 85, 96, 97, 156 💬
190 GRIN1 💬 [19] Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Huntington disease, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism Amantadine hydrochloride 💬 Amantadine [5] 2, 6, 8, 13, 127 💬
191 GRIN1 💬 [19] Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Huntington disease, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism Acamprosate 💬 Acamprosate [3] 2, 6, 206 💬
192 GRIN1 💬 [19] Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Huntington disease, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism Riluzole 💬 Riluzole [9] 2, 3, 5, 8, 13, 17, 18, 203, 206 💬
193 GRIN1 💬 [19] Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Huntington disease, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism Amantadine 💬 Amantadine [5] 2, 6, 8, 13, 127 💬
194 GRIN1 💬 [19] Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Huntington disease, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism Acamprosate calcium 💬 Acamprosate [3] 2, 6, 206 💬
195 GRIN1 💬 [19] Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Huntington disease, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism Dextromethorphan 💬 Dextromethorphan [10] 2, 6, 8, 13, 21, 46, 85, 96, 97, 156 💬
196 GRIN2A 💬 [20] Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Dopaminergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism, Systemic lupus erythematosus Memantine hydrochloride 💬 Memantine [8] 2, 6, 8, 13, 49, 127, 205, 206 💬
197 GRIN2A 💬 [20] Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Dopaminergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism, Systemic lupus erythematosus Riluzole 💬 Riluzole [9] 2, 3, 5, 8, 13, 17, 18, 203, 206 💬
198 GRIN2A 💬 [20] Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Dopaminergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism, Systemic lupus erythematosus Acamprosate 💬 Acamprosate [3] 2, 6, 206 💬
199 GRIN2A 💬 [20] Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Dopaminergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism, Systemic lupus erythematosus Dextromethorphan hydrobromide 💬 Dextromethorphan [10] 2, 6, 8, 13, 21, 46, 85, 96, 97, 156 💬
200 GRIN2A 💬 [20] Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Dopaminergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism, Systemic lupus erythematosus Memantine 💬 Memantine [8] 2, 6, 8, 13, 49, 127, 205, 206 💬
201 GRIN2A 💬 [20] Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Dopaminergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism, Systemic lupus erythematosus Acamprosate calcium 💬 Acamprosate [3] 2, 6, 206 💬
202 GRIN2A 💬 [20] Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Dopaminergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism, Systemic lupus erythematosus Esketamine 💬 Esketamine [7] 2, 4, 6, 70, 96, 97, 156 💬
203 GRIN2A 💬 [20] Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Dopaminergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism, Systemic lupus erythematosus Esketamine hydrochloride 💬 Esketamine [7] 2, 4, 6, 70, 96, 97, 156 💬
204 GRIN2A 💬 [20] Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Dopaminergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism, Systemic lupus erythematosus Dextromethorphan polistirex 💬 Dextromethorphan [10] 2, 6, 8, 13, 21, 46, 85, 96, 97, 156 💬
205 GRIN2A 💬 [20] Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Dopaminergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism, Systemic lupus erythematosus Amantadine hydrochloride 💬 Amantadine [5] 2, 6, 8, 13, 127 💬
206 GRIN2A 💬 [20] Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Dopaminergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism, Systemic lupus erythematosus Dextromethorphan 💬 Dextromethorphan [10] 2, 6, 8, 13, 21, 46, 85, 96, 97, 156 💬
207 GRIN2A 💬 [20] Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Dopaminergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism, Systemic lupus erythematosus Amantadine 💬 Amantadine [5] 2, 6, 8, 13, 127 💬
208 GRIN2B 💬 [21] Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Dopaminergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Huntington disease, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism, Systemic lupus erythematosus Acamprosate calcium 💬 Acamprosate [3] 2, 6, 206 💬
209 GRIN2B 💬 [21] Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Dopaminergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Huntington disease, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism, Systemic lupus erythematosus Dextromethorphan hydrobromide 💬 Dextromethorphan [10] 2, 6, 8, 13, 21, 46, 85, 96, 97, 156 💬
210 GRIN2B 💬 [21] Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Dopaminergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Huntington disease, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism, Systemic lupus erythematosus Amantadine hydrochloride 💬 Amantadine [5] 2, 6, 8, 13, 127 💬
211 GRIN2B 💬 [21] Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Dopaminergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Huntington disease, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism, Systemic lupus erythematosus Memantine 💬 Memantine [8] 2, 6, 8, 13, 49, 127, 205, 206 💬
212 GRIN2B 💬 [21] Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Dopaminergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Huntington disease, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism, Systemic lupus erythematosus Memantine hydrochloride 💬 Memantine [8] 2, 6, 8, 13, 49, 127, 205, 206 💬
213 GRIN2B 💬 [21] Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Dopaminergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Huntington disease, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism, Systemic lupus erythematosus Amantadine 💬 Amantadine [5] 2, 6, 8, 13, 127 💬
214 GRIN2B 💬 [21] Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Dopaminergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Huntington disease, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism, Systemic lupus erythematosus Dextromethorphan 💬 Dextromethorphan [10] 2, 6, 8, 13, 21, 46, 85, 96, 97, 156 💬
215 GRIN2B 💬 [21] Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Dopaminergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Huntington disease, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism, Systemic lupus erythematosus Riluzole 💬 Riluzole [9] 2, 3, 5, 8, 13, 17, 18, 203, 206 💬
216 GRIN2B 💬 [21] Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Dopaminergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Huntington disease, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism, Systemic lupus erythematosus Esketamine 💬 Esketamine [7] 2, 4, 6, 70, 96, 97, 156 💬
217 GRIN2B 💬 [21] Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Dopaminergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Huntington disease, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism, Systemic lupus erythematosus Acamprosate 💬 Acamprosate [3] 2, 6, 206 💬
218 GRIN2B 💬 [21] Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Dopaminergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Huntington disease, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism, Systemic lupus erythematosus Esketamine hydrochloride 💬 Esketamine [7] 2, 4, 6, 70, 96, 97, 156 💬
219 GRIN2B 💬 [21] Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Dopaminergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Huntington disease, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism, Systemic lupus erythematosus Dextromethorphan polistirex 💬 Dextromethorphan [10] 2, 6, 8, 13, 21, 46, 85, 96, 97, 156 💬
220 GRIN2C 💬 [16] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism Dextromethorphan polistirex 💬 Dextromethorphan [10] 2, 6, 8, 13, 21, 46, 85, 96, 97, 156 💬
221 GRIN2C 💬 [16] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism Dextromethorphan 💬 Dextromethorphan [10] 2, 6, 8, 13, 21, 46, 85, 96, 97, 156 💬
222 GRIN2C 💬 [16] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism Amantadine hydrochloride 💬 Amantadine [5] 2, 6, 8, 13, 127 💬
223 GRIN2C 💬 [16] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism Dextromethorphan hydrobromide 💬 Dextromethorphan [10] 2, 6, 8, 13, 21, 46, 85, 96, 97, 156 💬
224 GRIN2C 💬 [16] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism Esketamine hydrochloride 💬 Esketamine [7] 2, 4, 6, 70, 96, 97, 156 💬
225 GRIN2C 💬 [16] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism Memantine hydrochloride 💬 Memantine [8] 2, 6, 8, 13, 49, 127, 205, 206 💬
226 GRIN2C 💬 [16] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism Acamprosate 💬 Acamprosate [3] 2, 6, 206 💬
227 GRIN2C 💬 [16] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism Amantadine 💬 Amantadine [5] 2, 6, 8, 13, 127 💬
228 GRIN2C 💬 [16] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism Acamprosate calcium 💬 Acamprosate [3] 2, 6, 206 💬
229 GRIN2C 💬 [16] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism Esketamine 💬 Esketamine [7] 2, 4, 6, 70, 96, 97, 156 💬
230 GRIN2C 💬 [16] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism Riluzole 💬 Riluzole [9] 2, 3, 5, 8, 13, 17, 18, 203, 206 💬
231 GRIN2C 💬 [16] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism Memantine 💬 Memantine [8] 2, 6, 8, 13, 49, 127, 205, 206 💬
232 GRIN2D 💬 [16] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism Memantine hydrochloride 💬 Memantine [8] 2, 6, 8, 13, 49, 127, 205, 206 💬
233 GRIN2D 💬 [16] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism Acamprosate calcium 💬 Acamprosate [3] 2, 6, 206 💬
234 GRIN2D 💬 [16] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism Dextromethorphan hydrobromide 💬 Dextromethorphan [10] 2, 6, 8, 13, 21, 46, 85, 96, 97, 156 💬
235 GRIN2D 💬 [16] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism Amantadine hydrochloride 💬 Amantadine [5] 2, 6, 8, 13, 127 💬
236 GRIN2D 💬 [16] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism Riluzole 💬 Riluzole [9] 2, 3, 5, 8, 13, 17, 18, 203, 206 💬
237 GRIN2D 💬 [16] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism Esketamine hydrochloride 💬 Esketamine [7] 2, 4, 6, 70, 96, 97, 156 💬
238 GRIN2D 💬 [16] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism Amantadine 💬 Amantadine [5] 2, 6, 8, 13, 127 💬
239 GRIN2D 💬 [16] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism Acamprosate 💬 Acamprosate [3] 2, 6, 206 💬
240 GRIN2D 💬 [16] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism Dextromethorphan 💬 Dextromethorphan [10] 2, 6, 8, 13, 21, 46, 85, 96, 97, 156 💬
241 GRIN2D 💬 [16] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism Esketamine 💬 Esketamine [7] 2, 4, 6, 70, 96, 97, 156 💬
242 GRIN2D 💬 [16] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism Memantine 💬 Memantine [8] 2, 6, 8, 13, 49, 127, 205, 206 💬
243 GRIN2D 💬 [16] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism Dextromethorphan polistirex 💬 Dextromethorphan [10] 2, 6, 8, 13, 21, 46, 85, 96, 97, 156 💬
244 HLA-A 💬 [19] Endocytosis, Phagocytosis, Cellular senescence, Cell adhesion molecule (CAM) interaction, Antigen processing and presentation, Natural killer cell mediated cytotoxicity, Type I diabetes mellitus, Human cytomegalovirus infection, Human papillomavirus infection, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Herpes simplex virus 1 infection, Epstein-Barr virus infection, Human immunodeficiency virus 1 infection, Viral carcinogenesis, Autoimmune thyroid disease, Allograft rejection, Graft-versus-host disease, Viral myocarditis Glatiramer acetate 💬 Glatiramer [4] 2, 13, 96, 156 💬
245 HLA-B 💬 [19] Endocytosis, Phagocytosis, Cellular senescence, Cell adhesion molecule (CAM) interaction, Antigen processing and presentation, Natural killer cell mediated cytotoxicity, Type I diabetes mellitus, Human cytomegalovirus infection, Human papillomavirus infection, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Herpes simplex virus 1 infection, Epstein-Barr virus infection, Human immunodeficiency virus 1 infection, Viral carcinogenesis, Autoimmune thyroid disease, Allograft rejection, Graft-versus-host disease, Viral myocarditis Glatiramer acetate 💬 Glatiramer [4] 2, 13, 96, 156 💬
246 HLA-C 💬 [19] Endocytosis, Phagocytosis, Cellular senescence, Cell adhesion molecule (CAM) interaction, Antigen processing and presentation, Natural killer cell mediated cytotoxicity, Type I diabetes mellitus, Human cytomegalovirus infection, Human papillomavirus infection, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Herpes simplex virus 1 infection, Epstein-Barr virus infection, Human immunodeficiency virus 1 infection, Viral carcinogenesis, Autoimmune thyroid disease, Allograft rejection, Graft-versus-host disease, Viral myocarditis Glatiramer acetate 💬 Glatiramer [4] 2, 13, 96, 156 💬
247 HLA-DMA 💬 [24] Phagocytosis, Cell adhesion molecule (CAM) interaction, Antigen processing and presentation, Hematopoietic cell lineage, Th1 and Th2 cell differentiation, Th17 cell differentiation, Intestinal immune network for IgA production, Type I diabetes mellitus, Leishmaniasis, Toxoplasmosis, Staphylococcus aureus infection, Tuberculosis, Influenza A, Human T-cell leukemia virus 1 infection, Herpes simplex virus 1 infection, Epstein-Barr virus infection, Asthma, Autoimmune thyroid disease, Inflammatory bowel disease, Systemic lupus erythematosus, Rheumatoid arthritis, Allograft rejection, Graft-versus-host disease, Viral myocarditis Glatiramer acetate 💬 Glatiramer [4] 2, 13, 96, 156 💬
248 HLA-DMB 💬 [24] Phagocytosis, Cell adhesion molecule (CAM) interaction, Antigen processing and presentation, Hematopoietic cell lineage, Th1 and Th2 cell differentiation, Th17 cell differentiation, Intestinal immune network for IgA production, Type I diabetes mellitus, Leishmaniasis, Toxoplasmosis, Staphylococcus aureus infection, Tuberculosis, Influenza A, Human T-cell leukemia virus 1 infection, Herpes simplex virus 1 infection, Epstein-Barr virus infection, Asthma, Autoimmune thyroid disease, Inflammatory bowel disease, Systemic lupus erythematosus, Rheumatoid arthritis, Allograft rejection, Graft-versus-host disease, Viral myocarditis Glatiramer acetate 💬 Glatiramer [4] 2, 13, 96, 156 💬
249 HLA-DOA 💬 [24] Phagocytosis, Cell adhesion molecule (CAM) interaction, Antigen processing and presentation, Hematopoietic cell lineage, Th1 and Th2 cell differentiation, Th17 cell differentiation, Intestinal immune network for IgA production, Type I diabetes mellitus, Leishmaniasis, Toxoplasmosis, Staphylococcus aureus infection, Tuberculosis, Influenza A, Human T-cell leukemia virus 1 infection, Herpes simplex virus 1 infection, Epstein-Barr virus infection, Asthma, Autoimmune thyroid disease, Inflammatory bowel disease, Systemic lupus erythematosus, Rheumatoid arthritis, Allograft rejection, Graft-versus-host disease, Viral myocarditis Glatiramer acetate 💬 Glatiramer [4] 2, 13, 96, 156 💬
250 HLA-DOB 💬 [24] Phagocytosis, Cell adhesion molecule (CAM) interaction, Antigen processing and presentation, Hematopoietic cell lineage, Th1 and Th2 cell differentiation, Th17 cell differentiation, Intestinal immune network for IgA production, Type I diabetes mellitus, Leishmaniasis, Toxoplasmosis, Staphylococcus aureus infection, Tuberculosis, Influenza A, Human T-cell leukemia virus 1 infection, Herpes simplex virus 1 infection, Epstein-Barr virus infection, Asthma, Autoimmune thyroid disease, Inflammatory bowel disease, Systemic lupus erythematosus, Rheumatoid arthritis, Allograft rejection, Graft-versus-host disease, Viral myocarditis Glatiramer acetate 💬 Glatiramer [4] 2, 13, 96, 156 💬
251 HLA-DPA1 💬 [24] Phagocytosis, Cell adhesion molecule (CAM) interaction, Antigen processing and presentation, Hematopoietic cell lineage, Th1 and Th2 cell differentiation, Th17 cell differentiation, Intestinal immune network for IgA production, Type I diabetes mellitus, Leishmaniasis, Toxoplasmosis, Staphylococcus aureus infection, Tuberculosis, Influenza A, Human T-cell leukemia virus 1 infection, Herpes simplex virus 1 infection, Epstein-Barr virus infection, Asthma, Autoimmune thyroid disease, Inflammatory bowel disease, Systemic lupus erythematosus, Rheumatoid arthritis, Allograft rejection, Graft-versus-host disease, Viral myocarditis Glatiramer acetate 💬 Glatiramer [4] 2, 13, 96, 156 💬
252 HLA-DPB1 💬 [24] Phagocytosis, Cell adhesion molecule (CAM) interaction, Antigen processing and presentation, Hematopoietic cell lineage, Th1 and Th2 cell differentiation, Th17 cell differentiation, Intestinal immune network for IgA production, Type I diabetes mellitus, Leishmaniasis, Toxoplasmosis, Staphylococcus aureus infection, Tuberculosis, Influenza A, Human T-cell leukemia virus 1 infection, Herpes simplex virus 1 infection, Epstein-Barr virus infection, Asthma, Autoimmune thyroid disease, Inflammatory bowel disease, Systemic lupus erythematosus, Rheumatoid arthritis, Allograft rejection, Graft-versus-host disease, Viral myocarditis Glatiramer acetate 💬 Glatiramer [4] 2, 13, 96, 156 💬
253 HLA-DQA1 💬 [24] Phagocytosis, Cell adhesion molecule (CAM) interaction, Antigen processing and presentation, Hematopoietic cell lineage, Th1 and Th2 cell differentiation, Th17 cell differentiation, Intestinal immune network for IgA production, Type I diabetes mellitus, Leishmaniasis, Toxoplasmosis, Staphylococcus aureus infection, Tuberculosis, Influenza A, Human T-cell leukemia virus 1 infection, Herpes simplex virus 1 infection, Epstein-Barr virus infection, Asthma, Autoimmune thyroid disease, Inflammatory bowel disease, Systemic lupus erythematosus, Rheumatoid arthritis, Allograft rejection, Graft-versus-host disease, Viral myocarditis Glatiramer acetate 💬 Glatiramer [4] 2, 13, 96, 156 💬
254 HLA-DQA2 💬 [24] Phagocytosis, Cell adhesion molecule (CAM) interaction, Antigen processing and presentation, Hematopoietic cell lineage, Th1 and Th2 cell differentiation, Th17 cell differentiation, Intestinal immune network for IgA production, Type I diabetes mellitus, Leishmaniasis, Toxoplasmosis, Staphylococcus aureus infection, Tuberculosis, Influenza A, Human T-cell leukemia virus 1 infection, Herpes simplex virus 1 infection, Epstein-Barr virus infection, Asthma, Autoimmune thyroid disease, Inflammatory bowel disease, Systemic lupus erythematosus, Rheumatoid arthritis, Allograft rejection, Graft-versus-host disease, Viral myocarditis Glatiramer acetate 💬 Glatiramer [4] 2, 13, 96, 156 💬
255 HLA-DQB1 💬 [24] Phagocytosis, Cell adhesion molecule (CAM) interaction, Antigen processing and presentation, Hematopoietic cell lineage, Th1 and Th2 cell differentiation, Th17 cell differentiation, Intestinal immune network for IgA production, Type I diabetes mellitus, Leishmaniasis, Toxoplasmosis, Staphylococcus aureus infection, Tuberculosis, Influenza A, Human T-cell leukemia virus 1 infection, Herpes simplex virus 1 infection, Epstein-Barr virus infection, Asthma, Autoimmune thyroid disease, Inflammatory bowel disease, Systemic lupus erythematosus, Rheumatoid arthritis, Allograft rejection, Graft-versus-host disease, Viral myocarditis Glatiramer acetate 💬 Glatiramer [4] 2, 13, 96, 156 💬
256 HLA-DRA 💬 [24] Phagocytosis, Cell adhesion molecule (CAM) interaction, Antigen processing and presentation, Hematopoietic cell lineage, Th1 and Th2 cell differentiation, Th17 cell differentiation, Intestinal immune network for IgA production, Type I diabetes mellitus, Leishmaniasis, Toxoplasmosis, Staphylococcus aureus infection, Tuberculosis, Influenza A, Human T-cell leukemia virus 1 infection, Herpes simplex virus 1 infection, Epstein-Barr virus infection, Asthma, Autoimmune thyroid disease, Inflammatory bowel disease, Systemic lupus erythematosus, Rheumatoid arthritis, Allograft rejection, Graft-versus-host disease, Viral myocarditis Glatiramer acetate 💬 Glatiramer [4] 2, 13, 96, 156 💬
257 HLA-DRB1 💬 [24] Phagocytosis, Cell adhesion molecule (CAM) interaction, Antigen processing and presentation, Hematopoietic cell lineage, Th1 and Th2 cell differentiation, Th17 cell differentiation, Intestinal immune network for IgA production, Type I diabetes mellitus, Leishmaniasis, Toxoplasmosis, Staphylococcus aureus infection, Tuberculosis, Influenza A, Human T-cell leukemia virus 1 infection, Herpes simplex virus 1 infection, Epstein-Barr virus infection, Asthma, Autoimmune thyroid disease, Inflammatory bowel disease, Systemic lupus erythematosus, Rheumatoid arthritis, Allograft rejection, Graft-versus-host disease, Viral myocarditis Glatiramer acetate 💬 Glatiramer [4] 2, 13, 96, 156 💬
258 HLA-DRB3 💬 [24] Phagocytosis, Cell adhesion molecule (CAM) interaction, Antigen processing and presentation, Hematopoietic cell lineage, Th1 and Th2 cell differentiation, Th17 cell differentiation, Intestinal immune network for IgA production, Type I diabetes mellitus, Leishmaniasis, Toxoplasmosis, Staphylococcus aureus infection, Tuberculosis, Influenza A, Human T-cell leukemia virus 1 infection, Herpes simplex virus 1 infection, Epstein-Barr virus infection, Asthma, Autoimmune thyroid disease, Inflammatory bowel disease, Systemic lupus erythematosus, Rheumatoid arthritis, Allograft rejection, Graft-versus-host disease, Viral myocarditis Glatiramer acetate 💬 Glatiramer [4] 2, 13, 96, 156 💬
259 HLA-DRB4 💬 [24] Phagocytosis, Cell adhesion molecule (CAM) interaction, Antigen processing and presentation, Hematopoietic cell lineage, Th1 and Th2 cell differentiation, Th17 cell differentiation, Intestinal immune network for IgA production, Type I diabetes mellitus, Leishmaniasis, Toxoplasmosis, Staphylococcus aureus infection, Tuberculosis, Influenza A, Human T-cell leukemia virus 1 infection, Herpes simplex virus 1 infection, Epstein-Barr virus infection, Asthma, Autoimmune thyroid disease, Inflammatory bowel disease, Systemic lupus erythematosus, Rheumatoid arthritis, Allograft rejection, Graft-versus-host disease, Viral myocarditis Glatiramer acetate 💬 Glatiramer [4] 2, 13, 96, 156 💬
260 HLA-DRB5 💬 [24] Phagocytosis, Cell adhesion molecule (CAM) interaction, Antigen processing and presentation, Hematopoietic cell lineage, Th1 and Th2 cell differentiation, Th17 cell differentiation, Intestinal immune network for IgA production, Type I diabetes mellitus, Leishmaniasis, Toxoplasmosis, Staphylococcus aureus infection, Tuberculosis, Influenza A, Human T-cell leukemia virus 1 infection, Herpes simplex virus 1 infection, Epstein-Barr virus infection, Asthma, Autoimmune thyroid disease, Inflammatory bowel disease, Systemic lupus erythematosus, Rheumatoid arthritis, Allograft rejection, Graft-versus-host disease, Viral myocarditis Glatiramer acetate 💬 Glatiramer [4] 2, 13, 96, 156 💬
261 HLA-E 💬 [19] Endocytosis, Phagocytosis, Cellular senescence, Cell adhesion molecule (CAM) interaction, Antigen processing and presentation, Natural killer cell mediated cytotoxicity, Type I diabetes mellitus, Human cytomegalovirus infection, Human papillomavirus infection, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Herpes simplex virus 1 infection, Epstein-Barr virus infection, Human immunodeficiency virus 1 infection, Viral carcinogenesis, Autoimmune thyroid disease, Allograft rejection, Graft-versus-host disease, Viral myocarditis Glatiramer acetate 💬 Glatiramer [4] 2, 13, 96, 156 💬
262 HLA-F 💬 [18] Endocytosis, Phagocytosis, Cellular senescence, Cell adhesion molecule (CAM) interaction, Antigen processing and presentation, Type I diabetes mellitus, Human cytomegalovirus infection, Human papillomavirus infection, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Herpes simplex virus 1 infection, Epstein-Barr virus infection, Human immunodeficiency virus 1 infection, Viral carcinogenesis, Autoimmune thyroid disease, Allograft rejection, Graft-versus-host disease, Viral myocarditis Glatiramer acetate 💬 Glatiramer [4] 2, 13, 96, 156 💬
263 HLA-G 💬 [19] Endocytosis, Phagocytosis, Cellular senescence, Cell adhesion molecule (CAM) interaction, Antigen processing and presentation, Natural killer cell mediated cytotoxicity, Type I diabetes mellitus, Human cytomegalovirus infection, Human papillomavirus infection, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Herpes simplex virus 1 infection, Epstein-Barr virus infection, Human immunodeficiency virus 1 infection, Viral carcinogenesis, Autoimmune thyroid disease, Allograft rejection, Graft-versus-host disease, Viral myocarditis Glatiramer acetate 💬 Glatiramer [4] 2, 13, 96, 156 💬
264 HRH1 💬 [4] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Inflammatory mediator regulation of TRP channels Olanzapine 💬 Olanzapine [2] 2, 8 💬
265 HRH1 💬 [4] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Inflammatory mediator regulation of TRP channels Olanzapine pamoate 💬 Olanzapine [2] 2, 8 💬
266 HRH2 💬 [4] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Gastric acid secretion Cimetidine hydrochloride 💬 Cimetidine [2] 2, 254 💬
267 HRH2 💬 [4] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Gastric acid secretion Cimetidine 💬 Cimetidine [2] 2, 254 💬
268 HTR2A 💬 [6] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Gap junction, Serotonergic synapse, Inflammatory mediator regulation of TRP channels Olanzapine 💬 Olanzapine [2] 2, 8 💬
269 HTR2A 💬 [6] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Gap junction, Serotonergic synapse, Inflammatory mediator regulation of TRP channels Trazodone hydrochloride 💬 Trazodone [1] 2 💬
270 HTR2A 💬 [6] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Gap junction, Serotonergic synapse, Inflammatory mediator regulation of TRP channels Psilocybin 💬 Psilocybin [5] 2, 6, 13, 149, 206 💬
271 HTR2A 💬 [6] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Gap junction, Serotonergic synapse, Inflammatory mediator regulation of TRP channels Trazodone 💬 Trazodone [1] 2 💬
272 HTR2A 💬 [6] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Gap junction, Serotonergic synapse, Inflammatory mediator regulation of TRP channels Olanzapine pamoate 💬 Olanzapine [2] 2, 8 💬
273 HTR2B 💬 [6] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Gap junction, Serotonergic synapse, Inflammatory mediator regulation of TRP channels Olanzapine 💬 Olanzapine [2] 2, 8 💬
274 HTR2B 💬 [6] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Gap junction, Serotonergic synapse, Inflammatory mediator regulation of TRP channels Olanzapine pamoate 💬 Olanzapine [2] 2, 8 💬
275 HTR2B 💬 [6] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Gap junction, Serotonergic synapse, Inflammatory mediator regulation of TRP channels Trazodone hydrochloride 💬 Trazodone [1] 2 💬
276 HTR2B 💬 [6] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Gap junction, Serotonergic synapse, Inflammatory mediator regulation of TRP channels Trazodone 💬 Trazodone [1] 2 💬
277 HTR2C 💬 [6] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Gap junction, Serotonergic synapse, Inflammatory mediator regulation of TRP channels Olanzapine pamoate 💬 Olanzapine [2] 2, 8 💬
278 HTR2C 💬 [6] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Gap junction, Serotonergic synapse, Inflammatory mediator regulation of TRP channels Olanzapine 💬 Olanzapine [2] 2, 8 💬
279 HTR2C 💬 [6] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Gap junction, Serotonergic synapse, Inflammatory mediator regulation of TRP channels Trazodone 💬 Trazodone [1] 2 💬
280 HTR2C 💬 [6] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Gap junction, Serotonergic synapse, Inflammatory mediator regulation of TRP channels Trazodone hydrochloride 💬 Trazodone [1] 2 💬
281 HTR6 💬 [5] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Serotonergic synapse Olanzapine 💬 Olanzapine [2] 2, 8 💬
282 HTR6 💬 [5] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Serotonergic synapse Olanzapine pamoate 💬 Olanzapine [2] 2, 8 💬
283 IL1R1 💬 [13] MAPK signaling pathway, Cytokine-cytokine receptor interaction, NF-kappa B signaling pathway, Osteoclast differentiation, Hematopoietic cell lineage, Th17 cell differentiation, Inflammatory mediator regulation of TRP channels, Pathogenic Escherichia coli infection, Shigellosis, Amoebiasis, Human cytomegalovirus infection, Human T-cell leukemia virus 1 infection, Fluid shear stress and atherosclerosis Anakinra 💬 Anakinra [22] 2, 13, 15, 19, 28, 37, 41, 46, 49, 50, 54, 56, 57, 84, 86, 97, 106, 107, 149, 153, 266, 299 💬
284 IL1R2 💬 [7] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, Amoebiasis, Human T-cell leukemia virus 1 infection, Transcriptional misregulation in cancer, Prostate cancer, Fluid shear stress and atherosclerosis Anakinra 💬 Anakinra [22] 2, 13, 15, 19, 28, 37, 41, 46, 49, 50, 54, 56, 57, 84, 86, 97, 106, 107, 149, 153, 266, 299 💬
285 IL2RA 💬 [11] Cytokine-cytokine receptor interaction, Viral protein interaction with cytokine and cytokine receptor, Endocytosis, PI3K-Akt signaling pathway, JAK-STAT signaling pathway, Hematopoietic cell lineage, Th1 and Th2 cell differentiation, Th17 cell differentiation, Measles, Human T-cell leukemia virus 1 infection, Pathways in cancer Aldesleukin 💬 Aldesleukin [5] 2, 49, 65, 96, 97 💬
286 IL2RA 💬 [11] Cytokine-cytokine receptor interaction, Viral protein interaction with cytokine and cytokine receptor, Endocytosis, PI3K-Akt signaling pathway, JAK-STAT signaling pathway, Hematopoietic cell lineage, Th1 and Th2 cell differentiation, Th17 cell differentiation, Measles, Human T-cell leukemia virus 1 infection, Pathways in cancer Basiliximab 💬 Basiliximab [5] 2, 50, 97, 222, 228 💬
287 IL2RB 💬 [11] Cytokine-cytokine receptor interaction, Viral protein interaction with cytokine and cytokine receptor, Endocytosis, PI3K-Akt signaling pathway, JAK-STAT signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Measles, Human T-cell leukemia virus 1 infection, Pathways in cancer, Transcriptional misregulation in cancer Aldesleukin 💬 Aldesleukin [5] 2, 49, 65, 96, 97 💬
288 IL2RG 💬 [12] Cytokine-cytokine receptor interaction, Viral protein interaction with cytokine and cytokine receptor, Endocytosis, PI3K-Akt signaling pathway, JAK-STAT signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Measles, Human T-cell leukemia virus 1 infection, Pathways in cancer, Inflammatory bowel disease, Primary immunodeficiency Aldesleukin 💬 Aldesleukin [5] 2, 49, 65, 96, 97 💬
289 IL6R 💬 [11] Cytokine-cytokine receptor interaction, Viral protein interaction with cytokine and cytokine receptor, HIF-1 signaling pathway, PI3K-Akt signaling pathway, JAK-STAT signaling pathway, Hematopoietic cell lineage, Th17 cell differentiation, Non-alcoholic fatty liver disease, Human cytomegalovirus infection, Coronavirus disease, Pathways in cancer Tocilizumab 💬 Tocilizumab [26] 2, 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 65, 86, 107, 149, 153, 223, 266, 271, 298, 331 💬
290 IMPDH1 💬 [2] Purine metabolism, Drug metabolism - other enzymes Mycophenolate mofetil hydrochloride 💬 Mycophenolate mofetil [38] 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 46, 49, 51, 53, 57, 60, 61, 62, 63, 65, 66, 93, 95, 96, 118, 162, 164, 222, 223, 224, 226, 234, 283, 284, 285, 300 💬
291 IMPDH1 💬 [2] Purine metabolism, Drug metabolism - other enzymes Mycophenolate mofetil 💬 Mycophenolate mofetil [38] 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 46, 49, 51, 53, 57, 60, 61, 62, 63, 65, 66, 93, 95, 96, 118, 162, 164, 222, 223, 224, 226, 234, 283, 284, 285, 300 💬
292 IMPDH2 💬 [2] Purine metabolism, Drug metabolism - other enzymes Mycophenolate mofetil 💬 Mycophenolate mofetil [38] 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 46, 49, 51, 53, 57, 60, 61, 62, 63, 65, 66, 93, 95, 96, 118, 162, 164, 222, 223, 224, 226, 234, 283, 284, 285, 300 💬
293 IMPDH2 💬 [2] Purine metabolism, Drug metabolism - other enzymes Mycophenolate mofetil hydrochloride 💬 Mycophenolate mofetil [38] 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 46, 49, 51, 53, 57, 60, 61, 62, 63, 65, 66, 93, 95, 96, 118, 162, 164, 222, 223, 224, 226, 234, 283, 284, 285, 300 💬
294 JAK1 💬 [27] PI3K-Akt signaling pathway, Necroptosis, Osteoclast differentiation, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, NOD-like receptor signaling pathway, JAK-STAT signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Leishmaniasis, Toxoplasmosis, Tuberculosis, Hepatitis C, Hepatitis B, Measles, Human cytomegalovirus infection, Influenza A, Human papillomavirus infection, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Herpes simplex virus 1 infection, Epstein-Barr virus infection, Coronavirus disease, Pathways in cancer, Viral carcinogenesis, Pancreatic cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer Tofacitinib 💬 Tofacitinib [23] 2, 11, 35, 38, 39, 40, 44, 46, 49, 50, 51, 53, 56, 65, 66, 84, 96, 97, 107, 110, 162, 271, 300 💬
295 JAK1 💬 [27] PI3K-Akt signaling pathway, Necroptosis, Osteoclast differentiation, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, NOD-like receptor signaling pathway, JAK-STAT signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Leishmaniasis, Toxoplasmosis, Tuberculosis, Hepatitis C, Hepatitis B, Measles, Human cytomegalovirus infection, Influenza A, Human papillomavirus infection, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Herpes simplex virus 1 infection, Epstein-Barr virus infection, Coronavirus disease, Pathways in cancer, Viral carcinogenesis, Pancreatic cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer Tofacitinib citrate 💬 Tofacitinib [23] 2, 11, 35, 38, 39, 40, 44, 46, 49, 50, 51, 53, 56, 65, 66, 84, 96, 97, 107, 110, 162, 271, 300 💬
296 JAK1 💬 [27] PI3K-Akt signaling pathway, Necroptosis, Osteoclast differentiation, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, NOD-like receptor signaling pathway, JAK-STAT signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Leishmaniasis, Toxoplasmosis, Tuberculosis, Hepatitis C, Hepatitis B, Measles, Human cytomegalovirus infection, Influenza A, Human papillomavirus infection, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Herpes simplex virus 1 infection, Epstein-Barr virus infection, Coronavirus disease, Pathways in cancer, Viral carcinogenesis, Pancreatic cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer Baricitinib 💬 Baricitinib [24] 2, 13, 40, 41, 46, 49, 50, 51, 53, 54, 56, 63, 65, 84, 93, 107, 135, 162, 265, 268, 269, 300, 325, 345 💬
297 JAK2 💬 [25] Chemokine signaling pathway, Hormone signaling, Efferocytosis, PI3K-Akt signaling pathway, Necroptosis, Signaling pathways regulating pluripotency of stem cells, JAK-STAT signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Cholinergic synapse, Prolactin signaling pathway, Adipocytokine signaling pathway, AGE-RAGE signaling pathway in diabetic complications, Growth hormone synthesis, secretion and action, Leishmaniasis, Toxoplasmosis, Tuberculosis, Hepatitis B, Influenza A, Kaposi sarcoma-associated herpesvirus infection, Herpes simplex virus 1 infection, Pathways in cancer, Chemical carcinogenesis - receptor activation, PD-L1 expression and PD-1 checkpoint pathway in cancer, Lipid and atherosclerosis Baricitinib 💬 Baricitinib [24] 2, 13, 40, 41, 46, 49, 50, 51, 53, 54, 56, 63, 65, 84, 93, 107, 135, 162, 265, 268, 269, 300, 325, 345 💬
298 JAK2 💬 [25] Chemokine signaling pathway, Hormone signaling, Efferocytosis, PI3K-Akt signaling pathway, Necroptosis, Signaling pathways regulating pluripotency of stem cells, JAK-STAT signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Cholinergic synapse, Prolactin signaling pathway, Adipocytokine signaling pathway, AGE-RAGE signaling pathway in diabetic complications, Growth hormone synthesis, secretion and action, Leishmaniasis, Toxoplasmosis, Tuberculosis, Hepatitis B, Influenza A, Kaposi sarcoma-associated herpesvirus infection, Herpes simplex virus 1 infection, Pathways in cancer, Chemical carcinogenesis - receptor activation, PD-L1 expression and PD-1 checkpoint pathway in cancer, Lipid and atherosclerosis Tofacitinib citrate 💬 Tofacitinib [23] 2, 11, 35, 38, 39, 40, 44, 46, 49, 50, 51, 53, 56, 65, 66, 84, 96, 97, 107, 110, 162, 271, 300 💬
299 JAK2 💬 [25] Chemokine signaling pathway, Hormone signaling, Efferocytosis, PI3K-Akt signaling pathway, Necroptosis, Signaling pathways regulating pluripotency of stem cells, JAK-STAT signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Cholinergic synapse, Prolactin signaling pathway, Adipocytokine signaling pathway, AGE-RAGE signaling pathway in diabetic complications, Growth hormone synthesis, secretion and action, Leishmaniasis, Toxoplasmosis, Tuberculosis, Hepatitis B, Influenza A, Kaposi sarcoma-associated herpesvirus infection, Herpes simplex virus 1 infection, Pathways in cancer, Chemical carcinogenesis - receptor activation, PD-L1 expression and PD-1 checkpoint pathway in cancer, Lipid and atherosclerosis Tofacitinib 💬 Tofacitinib [23] 2, 11, 35, 38, 39, 40, 44, 46, 49, 50, 51, 53, 56, 65, 66, 84, 96, 97, 107, 110, 162, 271, 300 💬
300 JAK3 💬 [15] Chemokine signaling pathway, PI3K-Akt signaling pathway, Necroptosis, Signaling pathways regulating pluripotency of stem cells, JAK-STAT signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Hepatitis B, Measles, Human T-cell leukemia virus 1 infection, Epstein-Barr virus infection, Pathways in cancer, Viral carcinogenesis, Non-small cell lung cancer, Primary immunodeficiency Tofacitinib 💬 Tofacitinib [23] 2, 11, 35, 38, 39, 40, 44, 46, 49, 50, 51, 53, 56, 65, 66, 84, 96, 97, 107, 110, 162, 271, 300 💬
301 JAK3 💬 [15] Chemokine signaling pathway, PI3K-Akt signaling pathway, Necroptosis, Signaling pathways regulating pluripotency of stem cells, JAK-STAT signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Hepatitis B, Measles, Human T-cell leukemia virus 1 infection, Epstein-Barr virus infection, Pathways in cancer, Viral carcinogenesis, Non-small cell lung cancer, Primary immunodeficiency Tofacitinib citrate 💬 Tofacitinib [23] 2, 11, 35, 38, 39, 40, 44, 46, 49, 50, 51, 53, 56, 65, 66, 84, 96, 97, 107, 110, 162, 271, 300 💬
302 KCNQ1 💬 [6] Adrenergic signaling in cardiomyocytes, Cholinergic synapse, Gastric acid secretion, Pancreatic secretion, Protein digestion and absorption, Vibrio cholerae infection Ezogabine 💬 Ezogabine [2] 2, 144 💬
303 KCNQ2 💬 [2] IgSF CAM signaling, Cholinergic synapse Ezogabine 💬 Ezogabine [2] 2, 144 💬
304 KCNQ3 💬 [2] IgSF CAM signaling, Cholinergic synapse Ezogabine 💬 Ezogabine [2] 2, 144 💬
305 KCNQ4 💬 [1] Cholinergic synapse Ezogabine 💬 Ezogabine [2] 2, 144 💬
306 KCNQ5 💬 [1] Cholinergic synapse Ezogabine 💬 Ezogabine [2] 2, 144 💬
307 KIT 💬 [11] MAPK signaling pathway, Ras signaling pathway, Rap1 signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Hematopoietic cell lineage, Melanogenesis, Pathways in cancer, Acute myeloid leukemia, Breast cancer, Central carbon metabolism in cancer Masitinib 💬 Masitinib [6] 2, 5, 6, 13, 46, 96 💬
308 LIPC 💬 [2] Glycerolipid metabolism, Cholesterol metabolism Dextran sulfate sodium 💬 Dextran [5] 2, 62, 79, 96, 97 💬
309 LPL 💬 [4] Glycerolipid metabolism, PPAR signaling pathway, Cholesterol metabolism, Alzheimer disease Dextran sulfate sodium 💬 Dextran [5] 2, 62, 79, 96, 97 💬
310 MAOB 💬 [13] Glycine, serine and threonine metabolism, Arginine and proline metabolism, Histidine metabolism, Tyrosine metabolism, Phenylalanine metabolism, Tryptophan metabolism, Drug metabolism - cytochrome P450, Serotonergic synapse, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Amphetamine addiction, Alcoholism Rasagiline 💬 Rasagiline [4] 2, 5, 6, 17 💬
311 MAOB 💬 [13] Glycine, serine and threonine metabolism, Arginine and proline metabolism, Histidine metabolism, Tyrosine metabolism, Phenylalanine metabolism, Tryptophan metabolism, Drug metabolism - cytochrome P450, Serotonergic synapse, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Amphetamine addiction, Alcoholism Rasagiline mesylate 💬 Rasagiline [4] 2, 5, 6, 17 💬
312 MAOB 💬 [13] Glycine, serine and threonine metabolism, Arginine and proline metabolism, Histidine metabolism, Tyrosine metabolism, Phenylalanine metabolism, Tryptophan metabolism, Drug metabolism - cytochrome P450, Serotonergic synapse, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Amphetamine addiction, Alcoholism Rasagiline tartrate 💬 Rasagiline [4] 2, 5, 6, 17 💬
313 MAP2K1 💬 [90] MAPK signaling pathway, ErbB signaling pathway, Ras signaling pathway, Rap1 signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Chemokine signaling pathway, HIF-1 signaling pathway, FoxO signaling pathway, Sphingolipid signaling pathway, Phospholipase D signaling pathway, Oocyte meiosis, Autophagy - animal, Efferocytosis, mTOR signaling pathway, PI3K-Akt signaling pathway, Apoptosis, Cellular senescence, Vascular smooth muscle contraction, VEGF signaling pathway, Apelin signaling pathway, Osteoclast differentiation, Focal adhesion, IgSF CAM signaling, Cadherin signaling, Gap junction, Signaling pathways regulating pluripotency of stem cells, Neutrophil extracellular trap formation, Toll-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, T cell receptor signaling pathway, B cell receptor signaling pathway, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagosome formation, TNF signaling pathway, Long-term potentiation, Neurotrophin signaling pathway, Cholinergic synapse, Serotonergic synapse, Long-term depression, Regulation of actin cytoskeleton, Insulin signaling pathway, GnRH signaling pathway, Progesterone-mediated oocyte maturation, Estrogen signaling pathway, Melanogenesis, Prolactin signaling pathway, Thyroid hormone signaling pathway, Oxytocin signaling pathway, Relaxin signaling pathway, Parathyroid hormone synthesis, secretion and action, GnRH secretion, Cushing syndrome, Growth hormone synthesis, secretion and action, Alzheimer disease, Pathways of neurodegeneration - multiple diseases, Alcoholism, Salmonella infection, Yersinia infection, Hepatitis C, Hepatitis B, Human cytomegalovirus infection, Influenza A, Human papillomavirus infection, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Human immunodeficiency virus 1 infection, Pathways in cancer, Proteoglycans in cancer, MicroRNAs in cancer, Chemical carcinogenesis - receptor activation, Chemical carcinogenesis - reactive oxygen species, Colorectal cancer, Renal cell carcinoma, Pancreatic cancer, Endometrial cancer, Glioma, Prostate cancer, Thyroid cancer, Melanoma, Bladder cancer, Chronic myeloid leukemia, Acute myeloid leukemia, Non-small cell lung cancer, Breast cancer, Hepatocellular carcinoma, Gastric cancer, Central carbon metabolism in cancer, Choline metabolism in cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer Trametinib 💬 Trametinib [6] 2, 34, 58, 195, 279, 280 💬
314 MAP2K1 💬 [90] MAPK signaling pathway, ErbB signaling pathway, Ras signaling pathway, Rap1 signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Chemokine signaling pathway, HIF-1 signaling pathway, FoxO signaling pathway, Sphingolipid signaling pathway, Phospholipase D signaling pathway, Oocyte meiosis, Autophagy - animal, Efferocytosis, mTOR signaling pathway, PI3K-Akt signaling pathway, Apoptosis, Cellular senescence, Vascular smooth muscle contraction, VEGF signaling pathway, Apelin signaling pathway, Osteoclast differentiation, Focal adhesion, IgSF CAM signaling, Cadherin signaling, Gap junction, Signaling pathways regulating pluripotency of stem cells, Neutrophil extracellular trap formation, Toll-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, T cell receptor signaling pathway, B cell receptor signaling pathway, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagosome formation, TNF signaling pathway, Long-term potentiation, Neurotrophin signaling pathway, Cholinergic synapse, Serotonergic synapse, Long-term depression, Regulation of actin cytoskeleton, Insulin signaling pathway, GnRH signaling pathway, Progesterone-mediated oocyte maturation, Estrogen signaling pathway, Melanogenesis, Prolactin signaling pathway, Thyroid hormone signaling pathway, Oxytocin signaling pathway, Relaxin signaling pathway, Parathyroid hormone synthesis, secretion and action, GnRH secretion, Cushing syndrome, Growth hormone synthesis, secretion and action, Alzheimer disease, Pathways of neurodegeneration - multiple diseases, Alcoholism, Salmonella infection, Yersinia infection, Hepatitis C, Hepatitis B, Human cytomegalovirus infection, Influenza A, Human papillomavirus infection, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Human immunodeficiency virus 1 infection, Pathways in cancer, Proteoglycans in cancer, MicroRNAs in cancer, Chemical carcinogenesis - receptor activation, Chemical carcinogenesis - reactive oxygen species, Colorectal cancer, Renal cell carcinoma, Pancreatic cancer, Endometrial cancer, Glioma, Prostate cancer, Thyroid cancer, Melanoma, Bladder cancer, Chronic myeloid leukemia, Acute myeloid leukemia, Non-small cell lung cancer, Breast cancer, Hepatocellular carcinoma, Gastric cancer, Central carbon metabolism in cancer, Choline metabolism in cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer Trametinib dimethyl sulfoxide 💬 Trametinib [6] 2, 34, 58, 195, 279, 280 💬
315 MAP2K2 💬 [78] MAPK signaling pathway, ErbB signaling pathway, Ras signaling pathway, Rap1 signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, HIF-1 signaling pathway, FoxO signaling pathway, Sphingolipid signaling pathway, Phospholipase D signaling pathway, Autophagy - animal, Efferocytosis, mTOR signaling pathway, PI3K-Akt signaling pathway, Apoptosis, Cellular senescence, Vascular smooth muscle contraction, VEGF signaling pathway, Apelin signaling pathway, IgSF CAM signaling, Cadherin signaling, Gap junction, Signaling pathways regulating pluripotency of stem cells, Neutrophil extracellular trap formation, Toll-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, T cell receptor signaling pathway, B cell receptor signaling pathway, Fc epsilon RI signaling pathway, Long-term potentiation, Neurotrophin signaling pathway, Long-term depression, Regulation of actin cytoskeleton, Insulin signaling pathway, GnRH signaling pathway, Estrogen signaling pathway, Melanogenesis, Prolactin signaling pathway, Thyroid hormone signaling pathway, Oxytocin signaling pathway, Relaxin signaling pathway, GnRH secretion, Cushing syndrome, Growth hormone synthesis, secretion and action, Alzheimer disease, Pathways of neurodegeneration - multiple diseases, Salmonella infection, Yersinia infection, Hepatitis C, Hepatitis B, Human cytomegalovirus infection, Influenza A, Human papillomavirus infection, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Human immunodeficiency virus 1 infection, Pathways in cancer, Proteoglycans in cancer, MicroRNAs in cancer, Chemical carcinogenesis - receptor activation, Chemical carcinogenesis - reactive oxygen species, Colorectal cancer, Renal cell carcinoma, Endometrial cancer, Glioma, Prostate cancer, Thyroid cancer, Melanoma, Bladder cancer, Chronic myeloid leukemia, Acute myeloid leukemia, Non-small cell lung cancer, Breast cancer, Hepatocellular carcinoma, Gastric cancer, Central carbon metabolism in cancer, Choline metabolism in cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer Trametinib 💬 Trametinib [6] 2, 34, 58, 195, 279, 280 💬
316 MAP2K2 💬 [78] MAPK signaling pathway, ErbB signaling pathway, Ras signaling pathway, Rap1 signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, HIF-1 signaling pathway, FoxO signaling pathway, Sphingolipid signaling pathway, Phospholipase D signaling pathway, Autophagy - animal, Efferocytosis, mTOR signaling pathway, PI3K-Akt signaling pathway, Apoptosis, Cellular senescence, Vascular smooth muscle contraction, VEGF signaling pathway, Apelin signaling pathway, IgSF CAM signaling, Cadherin signaling, Gap junction, Signaling pathways regulating pluripotency of stem cells, Neutrophil extracellular trap formation, Toll-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, T cell receptor signaling pathway, B cell receptor signaling pathway, Fc epsilon RI signaling pathway, Long-term potentiation, Neurotrophin signaling pathway, Long-term depression, Regulation of actin cytoskeleton, Insulin signaling pathway, GnRH signaling pathway, Estrogen signaling pathway, Melanogenesis, Prolactin signaling pathway, Thyroid hormone signaling pathway, Oxytocin signaling pathway, Relaxin signaling pathway, GnRH secretion, Cushing syndrome, Growth hormone synthesis, secretion and action, Alzheimer disease, Pathways of neurodegeneration - multiple diseases, Salmonella infection, Yersinia infection, Hepatitis C, Hepatitis B, Human cytomegalovirus infection, Influenza A, Human papillomavirus infection, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Human immunodeficiency virus 1 infection, Pathways in cancer, Proteoglycans in cancer, MicroRNAs in cancer, Chemical carcinogenesis - receptor activation, Chemical carcinogenesis - reactive oxygen species, Colorectal cancer, Renal cell carcinoma, Endometrial cancer, Glioma, Prostate cancer, Thyroid cancer, Melanoma, Bladder cancer, Chronic myeloid leukemia, Acute myeloid leukemia, Non-small cell lung cancer, Breast cancer, Hepatocellular carcinoma, Gastric cancer, Central carbon metabolism in cancer, Choline metabolism in cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer Trametinib dimethyl sulfoxide 💬 Trametinib [6] 2, 34, 58, 195, 279, 280 💬
317 MC2R 💬 [6] cAMP signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome Corticotropin, repository 💬 Corticotropin [10] 2, 13, 46, 75, 78, 81, 84, 145, 205, 222 💬
318 MC2R 💬 [6] cAMP signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome Corticotropin 💬 Corticotropin [10] 2, 13, 46, 75, 78, 81, 84, 145, 205, 222 💬
319 MPO 💬 [5] Drug metabolism - other enzymes, Phagocytosis, Neutrophil extracellular trap formation, Transcriptional misregulation in cancer, Acute myeloid leukemia Verdiperstat 💬 Verdiperstat [3] 2, 17, 127 💬
320 MTNR1A 💬 [2] Neuroactive ligand-receptor interaction, Circadian entrainment Melatonin 💬 Melatonin [18] 2, 6, 8, 13, 37, 46, 49, 72, 78, 86, 90, 96, 97, 145, 149, 159, 202, 265 💬
321 MTNR1B 💬 [2] Neuroactive ligand-receptor interaction, Circadian entrainment Melatonin 💬 Melatonin [18] 2, 6, 8, 13, 37, 46, 49, 72, 78, 86, 90, 96, 97, 145, 149, 159, 202, 265 💬
322 NLRP3 💬 [12] Necroptosis, NOD-like receptor signaling pathway, Cytosolic DNA-sensing pathway, C-type lectin receptor signaling pathway, Pathogenic Escherichia coli infection, Shigellosis, Salmonella infection, Pertussis, Yersinia infection, Influenza A, Coronavirus disease, Lipid and atherosclerosis Usnoflast 💬 Usnoflast [1] 2 💬
323 NR3C1 💬 [1] Neuroactive ligand-receptor interaction Betamethasone benzoate 💬 Betamethasone [9] 2, 28, 46, 56, 65, 83, 90, 96, 235 💬
324 NR3C1 💬 [1] Neuroactive ligand-receptor interaction Methylprednisolone 💬 Methylprednisolone [51] 2, 6, 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 95, 96, 97, 111, 127, 145, 162, 164, 211, 222, 223, 224, 271, 283, 284, 285, 296, 300 💬
325 NR3C1 💬 [1] Neuroactive ligand-receptor interaction Betamethasone 💬 Betamethasone [9] 2, 28, 46, 56, 65, 83, 90, 96, 235 💬
326 NR3C1 💬 [1] Neuroactive ligand-receptor interaction Betamethasone valerate 💬 Betamethasone [9] 2, 28, 46, 56, 65, 83, 90, 96, 235 💬
327 NR3C1 💬 [1] Neuroactive ligand-receptor interaction Betamethasone sodium phosphate 💬 Betamethasone [9] 2, 28, 46, 56, 65, 83, 90, 96, 235 💬
328 NR3C1 💬 [1] Neuroactive ligand-receptor interaction Methylprednisolone acetate 💬 Methylprednisolone [51] 2, 6, 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 95, 96, 97, 111, 127, 145, 162, 164, 211, 222, 223, 224, 271, 283, 284, 285, 296, 300 💬
329 NR3C1 💬 [1] Neuroactive ligand-receptor interaction Betamethasone dipropionate 💬 Betamethasone [9] 2, 28, 46, 56, 65, 83, 90, 96, 235 💬
330 NR3C1 💬 [1] Neuroactive ligand-receptor interaction Prednisone 💬 Prednisone [58] 2, 11, 13, 14, 18, 19, 26, 28, 35, 40, 41, 42, 43, 44, 45, 46, 48, 49, 50, 51, 53, 60, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 90, 93, 95, 96, 97, 113, 127, 145, 162, 164, 205, 222, 223, 224, 228, 251, 269, 283, 284, 285, 288, 299, 300, 303, 307, 331 💬
331 NR3C1 💬 [1] Neuroactive ligand-receptor interaction Betamethasone acetate 💬 Betamethasone [9] 2, 28, 46, 56, 65, 83, 90, 96, 235 💬
332 NR3C1 💬 [1] Neuroactive ligand-receptor interaction Dazucorilant 💬 Dazucorilant [1] 2 💬
333 PDE1B 💬 [6] Purine metabolism, Calcium signaling pathway, Olfactory transduction, Taste transduction, Renin secretion, Morphine addiction Caffeine citrate 💬 Caffeine [8] 2, 6, 13, 21, 46, 96, 97, 265 💬
334 PDE1B 💬 [6] Purine metabolism, Calcium signaling pathway, Olfactory transduction, Taste transduction, Renin secretion, Morphine addiction Caffeine 💬 Caffeine [8] 2, 6, 13, 21, 46, 96, 97, 265 💬
335 PDE2A 💬 [5] Purine metabolism, cGMP-PKG signaling pathway, Olfactory transduction, Aldosterone synthesis and secretion, Morphine addiction Caffeine citrate 💬 Caffeine [8] 2, 6, 13, 21, 46, 96, 97, 265 💬
336 PDE2A 💬 [5] Purine metabolism, cGMP-PKG signaling pathway, Olfactory transduction, Aldosterone synthesis and secretion, Morphine addiction Caffeine 💬 Caffeine [8] 2, 6, 13, 21, 46, 96, 97, 265 💬
337 PDE3A 💬 [5] Purine metabolism, cGMP-PKG signaling pathway, cAMP signaling pathway, Renin secretion, Morphine addiction Levosimendan 💬 Levosimendan [2] 2, 57 💬
338 PDE3A 💬 [5] Purine metabolism, cGMP-PKG signaling pathway, cAMP signaling pathway, Renin secretion, Morphine addiction Caffeine citrate 💬 Caffeine [8] 2, 6, 13, 21, 46, 96, 97, 265 💬
339 PDE3A 💬 [5] Purine metabolism, cGMP-PKG signaling pathway, cAMP signaling pathway, Renin secretion, Morphine addiction Caffeine 💬 Caffeine [8] 2, 6, 13, 21, 46, 96, 97, 265 💬
340 PDE3A 💬 [5] Purine metabolism, cGMP-PKG signaling pathway, cAMP signaling pathway, Renin secretion, Morphine addiction Ibudilast 💬 Ibudilast [2] 2, 13 💬
341 PDE3B 💬 [10] Purine metabolism, cGMP-PKG signaling pathway, cAMP signaling pathway, Apelin signaling pathway, Insulin signaling pathway, Progesterone-mediated oocyte maturation, Glucagon signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Morphine addiction Ibudilast 💬 Ibudilast [2] 2, 13 💬
342 PDE3B 💬 [10] Purine metabolism, cGMP-PKG signaling pathway, cAMP signaling pathway, Apelin signaling pathway, Insulin signaling pathway, Progesterone-mediated oocyte maturation, Glucagon signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Morphine addiction Levosimendan 💬 Levosimendan [2] 2, 57 💬
343 PDE3B 💬 [10] Purine metabolism, cGMP-PKG signaling pathway, cAMP signaling pathway, Apelin signaling pathway, Insulin signaling pathway, Progesterone-mediated oocyte maturation, Glucagon signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Morphine addiction Caffeine citrate 💬 Caffeine [8] 2, 6, 13, 21, 46, 96, 97, 265 💬
344 PDE3B 💬 [10] Purine metabolism, cGMP-PKG signaling pathway, cAMP signaling pathway, Apelin signaling pathway, Insulin signaling pathway, Progesterone-mediated oocyte maturation, Glucagon signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Morphine addiction Caffeine 💬 Caffeine [8] 2, 6, 13, 21, 46, 96, 97, 265 💬
345 PDE4A 💬 [4] Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Caffeine 💬 Caffeine [8] 2, 6, 13, 21, 46, 96, 97, 265 💬
346 PDE4A 💬 [4] Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Caffeine citrate 💬 Caffeine [8] 2, 6, 13, 21, 46, 96, 97, 265 💬
347 PDE4A 💬 [4] Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Ibudilast 💬 Ibudilast [2] 2, 13 💬
348 PDE4B 💬 [4] Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Caffeine 💬 Caffeine [8] 2, 6, 13, 21, 46, 96, 97, 265 💬
349 PDE4B 💬 [4] Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Caffeine citrate 💬 Caffeine [8] 2, 6, 13, 21, 46, 96, 97, 265 💬
350 PDE4B 💬 [4] Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Ibudilast 💬 Ibudilast [2] 2, 13 💬
351 PDE4B 💬 [4] Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Nerandomilast 💬 Nerandomilast [3] 2, 51, 85 💬
352 PDE4C 💬 [4] Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Caffeine 💬 Caffeine [8] 2, 6, 13, 21, 46, 96, 97, 265 💬
353 PDE4C 💬 [4] Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Caffeine citrate 💬 Caffeine [8] 2, 6, 13, 21, 46, 96, 97, 265 💬
354 PDE4C 💬 [4] Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Ibudilast 💬 Ibudilast [2] 2, 13 💬
355 PDE4D 💬 [4] Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Caffeine citrate 💬 Caffeine [8] 2, 6, 13, 21, 46, 96, 97, 265 💬
356 PDE4D 💬 [4] Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Caffeine 💬 Caffeine [8] 2, 6, 13, 21, 46, 96, 97, 265 💬
357 PDE4D 💬 [4] Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Ibudilast 💬 Ibudilast [2] 2, 13 💬
358 PDE5A 💬 [2] Purine metabolism, cGMP-PKG signaling pathway Caffeine citrate 💬 Caffeine [8] 2, 6, 13, 21, 46, 96, 97, 265 💬
359 PDE5A 💬 [2] Purine metabolism, cGMP-PKG signaling pathway Caffeine 💬 Caffeine [8] 2, 6, 13, 21, 46, 96, 97, 265 💬
360 PGR 💬 [5] Oocyte meiosis, Progesterone-mediated oocyte maturation, Estrogen signaling pathway, Chemical carcinogenesis - receptor activation, Breast cancer Megestrol 💬 Megestrol [2] 2, 76 💬
361 PML 💬 [7] Ubiquitin mediated proteolysis, Endocytosis, Influenza A, Herpes simplex virus 1 infection, Pathways in cancer, Transcriptional misregulation in cancer, Acute myeloid leukemia Tretinoin 💬 Tretinoin [4] 2, 62, 63, 75 💬
362 PPARG 💬 [12] PPAR signaling pathway, Efferocytosis, AMPK signaling pathway, Longevity regulating pathway, Osteoclast differentiation, Thermogenesis, Non-alcoholic fatty liver disease, Huntington disease, Pathways in cancer, Transcriptional misregulation in cancer, Thyroid cancer, Lipid and atherosclerosis Pioglitazone 💬 Pioglitazone [17] 2, 6, 13, 15, 20, 46, 49, 65, 67, 81, 86, 96, 223, 229, 265, 298, 299 💬
363 PPARG 💬 [12] PPAR signaling pathway, Efferocytosis, AMPK signaling pathway, Longevity regulating pathway, Osteoclast differentiation, Thermogenesis, Non-alcoholic fatty liver disease, Huntington disease, Pathways in cancer, Transcriptional misregulation in cancer, Thyroid cancer, Lipid and atherosclerosis Pioglitazone hydrochloride 💬 Pioglitazone [17] 2, 6, 13, 15, 20, 46, 49, 65, 67, 81, 86, 96, 223, 229, 265, 298, 299 💬
364 PPP3CA 💬 [33] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, Oocyte meiosis, Cellular senescence, Wnt signaling pathway, Axon guidance, VEGF signaling pathway, Osteoclast differentiation, C-type lectin receptor signaling pathway, Natural killer cell mediated cytotoxicity, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, B cell receptor signaling pathway, Long-term potentiation, Glutamatergic synapse, Dopaminergic synapse, Oxytocin signaling pathway, Glucagon signaling pathway, Renin secretion, Alzheimer disease, Amyotrophic lateral sclerosis, Prion disease, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Tuberculosis, Human cytomegalovirus infection, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Human immunodeficiency virus 1 infection, PD-L1 expression and PD-1 checkpoint pathway in cancer, Lipid and atherosclerosis Tacrolimus 💬 Tacrolimus [37] 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 57, 60, 61, 62, 63, 65, 66, 95, 96, 97, 113, 151, 158, 164, 222, 223, 224, 226, 227, 228, 234, 283, 284, 285, 286, 299 💬
365 PPP3CA 💬 [33] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, Oocyte meiosis, Cellular senescence, Wnt signaling pathway, Axon guidance, VEGF signaling pathway, Osteoclast differentiation, C-type lectin receptor signaling pathway, Natural killer cell mediated cytotoxicity, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, B cell receptor signaling pathway, Long-term potentiation, Glutamatergic synapse, Dopaminergic synapse, Oxytocin signaling pathway, Glucagon signaling pathway, Renin secretion, Alzheimer disease, Amyotrophic lateral sclerosis, Prion disease, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Tuberculosis, Human cytomegalovirus infection, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Human immunodeficiency virus 1 infection, PD-L1 expression and PD-1 checkpoint pathway in cancer, Lipid and atherosclerosis Tacrolimus 💬 Tacrolimus [37] 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 57, 60, 61, 62, 63, 65, 66, 95, 96, 97, 113, 151, 158, 164, 222, 223, 224, 226, 227, 228, 234, 283, 284, 285, 286, 299 💬
366 PPP3CB 💬 [33] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, Oocyte meiosis, Cellular senescence, Wnt signaling pathway, Axon guidance, VEGF signaling pathway, Osteoclast differentiation, C-type lectin receptor signaling pathway, Natural killer cell mediated cytotoxicity, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, B cell receptor signaling pathway, Long-term potentiation, Glutamatergic synapse, Dopaminergic synapse, Oxytocin signaling pathway, Glucagon signaling pathway, Renin secretion, Alzheimer disease, Amyotrophic lateral sclerosis, Prion disease, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Tuberculosis, Human cytomegalovirus infection, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Human immunodeficiency virus 1 infection, PD-L1 expression and PD-1 checkpoint pathway in cancer, Lipid and atherosclerosis Tacrolimus 💬 Tacrolimus [37] 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 57, 60, 61, 62, 63, 65, 66, 95, 96, 97, 113, 151, 158, 164, 222, 223, 224, 226, 227, 228, 234, 283, 284, 285, 286, 299 💬
367 PPP3CB 💬 [33] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, Oocyte meiosis, Cellular senescence, Wnt signaling pathway, Axon guidance, VEGF signaling pathway, Osteoclast differentiation, C-type lectin receptor signaling pathway, Natural killer cell mediated cytotoxicity, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, B cell receptor signaling pathway, Long-term potentiation, Glutamatergic synapse, Dopaminergic synapse, Oxytocin signaling pathway, Glucagon signaling pathway, Renin secretion, Alzheimer disease, Amyotrophic lateral sclerosis, Prion disease, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Tuberculosis, Human cytomegalovirus infection, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Human immunodeficiency virus 1 infection, PD-L1 expression and PD-1 checkpoint pathway in cancer, Lipid and atherosclerosis Tacrolimus 💬 Tacrolimus [37] 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 57, 60, 61, 62, 63, 65, 66, 95, 96, 97, 113, 151, 158, 164, 222, 223, 224, 226, 227, 228, 234, 283, 284, 285, 286, 299 💬
368 PPP3CC 💬 [33] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, Oocyte meiosis, Cellular senescence, Wnt signaling pathway, Axon guidance, VEGF signaling pathway, Osteoclast differentiation, C-type lectin receptor signaling pathway, Natural killer cell mediated cytotoxicity, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, B cell receptor signaling pathway, Long-term potentiation, Glutamatergic synapse, Dopaminergic synapse, Oxytocin signaling pathway, Glucagon signaling pathway, Renin secretion, Alzheimer disease, Amyotrophic lateral sclerosis, Prion disease, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Tuberculosis, Human cytomegalovirus infection, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Human immunodeficiency virus 1 infection, PD-L1 expression and PD-1 checkpoint pathway in cancer, Lipid and atherosclerosis Tacrolimus 💬 Tacrolimus [37] 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 57, 60, 61, 62, 63, 65, 66, 95, 96, 97, 113, 151, 158, 164, 222, 223, 224, 226, 227, 228, 234, 283, 284, 285, 286, 299 💬
369 PPP3CC 💬 [33] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, Oocyte meiosis, Cellular senescence, Wnt signaling pathway, Axon guidance, VEGF signaling pathway, Osteoclast differentiation, C-type lectin receptor signaling pathway, Natural killer cell mediated cytotoxicity, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, B cell receptor signaling pathway, Long-term potentiation, Glutamatergic synapse, Dopaminergic synapse, Oxytocin signaling pathway, Glucagon signaling pathway, Renin secretion, Alzheimer disease, Amyotrophic lateral sclerosis, Prion disease, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Tuberculosis, Human cytomegalovirus infection, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Human immunodeficiency virus 1 infection, PD-L1 expression and PD-1 checkpoint pathway in cancer, Lipid and atherosclerosis Tacrolimus 💬 Tacrolimus [37] 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 57, 60, 61, 62, 63, 65, 66, 95, 96, 97, 113, 151, 158, 164, 222, 223, 224, 226, 227, 228, 234, 283, 284, 285, 286, 299 💬
370 PPP3R1 💬 [32] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, Oocyte meiosis, Cellular senescence, Wnt signaling pathway, Axon guidance, VEGF signaling pathway, Osteoclast differentiation, C-type lectin receptor signaling pathway, Natural killer cell mediated cytotoxicity, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, B cell receptor signaling pathway, Long-term potentiation, Glutamatergic synapse, Oxytocin signaling pathway, Glucagon signaling pathway, Renin secretion, Alzheimer disease, Amyotrophic lateral sclerosis, Prion disease, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Tuberculosis, Human cytomegalovirus infection, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Human immunodeficiency virus 1 infection, PD-L1 expression and PD-1 checkpoint pathway in cancer, Lipid and atherosclerosis Tacrolimus 💬 Tacrolimus [37] 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 57, 60, 61, 62, 63, 65, 66, 95, 96, 97, 113, 151, 158, 164, 222, 223, 224, 226, 227, 228, 234, 283, 284, 285, 286, 299 💬
371 PPP3R1 💬 [32] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, Oocyte meiosis, Cellular senescence, Wnt signaling pathway, Axon guidance, VEGF signaling pathway, Osteoclast differentiation, C-type lectin receptor signaling pathway, Natural killer cell mediated cytotoxicity, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, B cell receptor signaling pathway, Long-term potentiation, Glutamatergic synapse, Oxytocin signaling pathway, Glucagon signaling pathway, Renin secretion, Alzheimer disease, Amyotrophic lateral sclerosis, Prion disease, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Tuberculosis, Human cytomegalovirus infection, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Human immunodeficiency virus 1 infection, PD-L1 expression and PD-1 checkpoint pathway in cancer, Lipid and atherosclerosis Tacrolimus 💬 Tacrolimus [37] 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 57, 60, 61, 62, 63, 65, 66, 95, 96, 97, 113, 151, 158, 164, 222, 223, 224, 226, 227, 228, 234, 283, 284, 285, 286, 299 💬
372 PPP3R2 💬 [32] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, Oocyte meiosis, Cellular senescence, Wnt signaling pathway, Axon guidance, VEGF signaling pathway, Osteoclast differentiation, C-type lectin receptor signaling pathway, Natural killer cell mediated cytotoxicity, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, B cell receptor signaling pathway, Long-term potentiation, Glutamatergic synapse, Oxytocin signaling pathway, Glucagon signaling pathway, Renin secretion, Alzheimer disease, Amyotrophic lateral sclerosis, Prion disease, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Tuberculosis, Human cytomegalovirus infection, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Human immunodeficiency virus 1 infection, PD-L1 expression and PD-1 checkpoint pathway in cancer, Lipid and atherosclerosis Tacrolimus 💬 Tacrolimus [37] 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 57, 60, 61, 62, 63, 65, 66, 95, 96, 97, 113, 151, 158, 164, 222, 223, 224, 226, 227, 228, 234, 283, 284, 285, 286, 299 💬
373 PPP3R2 💬 [32] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, Oocyte meiosis, Cellular senescence, Wnt signaling pathway, Axon guidance, VEGF signaling pathway, Osteoclast differentiation, C-type lectin receptor signaling pathway, Natural killer cell mediated cytotoxicity, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, B cell receptor signaling pathway, Long-term potentiation, Glutamatergic synapse, Oxytocin signaling pathway, Glucagon signaling pathway, Renin secretion, Alzheimer disease, Amyotrophic lateral sclerosis, Prion disease, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Tuberculosis, Human cytomegalovirus infection, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Human immunodeficiency virus 1 infection, PD-L1 expression and PD-1 checkpoint pathway in cancer, Lipid and atherosclerosis Tacrolimus 💬 Tacrolimus [37] 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 57, 60, 61, 62, 63, 65, 66, 95, 96, 97, 113, 151, 158, 164, 222, 223, 224, 226, 227, 228, 234, 283, 284, 285, 286, 299 💬
374 PRKAA1 💬 [20] FoxO signaling pathway, Autophagy - animal, mTOR signaling pathway, PI3K-Akt signaling pathway, AMPK signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Apelin signaling pathway, Tight junction, Circadian rhythm, Thermogenesis, Insulin signaling pathway, Adipocytokine signaling pathway, Oxytocin signaling pathway, Glucagon signaling pathway, Insulin resistance, Non-alcoholic fatty liver disease, Alcoholic liver disease, Hypertrophic cardiomyopathy, Fluid shear stress and atherosclerosis Metformin 💬 Metformin [31] 2, 6, 8, 13, 46, 49, 60, 65, 66, 67, 74, 75, 77, 81, 84, 85, 86, 97, 113, 127, 158, 206, 218, 222, 225, 233, 265, 285, 298, 299, 301 💬
375 PRKAA1 💬 [20] FoxO signaling pathway, Autophagy - animal, mTOR signaling pathway, PI3K-Akt signaling pathway, AMPK signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Apelin signaling pathway, Tight junction, Circadian rhythm, Thermogenesis, Insulin signaling pathway, Adipocytokine signaling pathway, Oxytocin signaling pathway, Glucagon signaling pathway, Insulin resistance, Non-alcoholic fatty liver disease, Alcoholic liver disease, Hypertrophic cardiomyopathy, Fluid shear stress and atherosclerosis Metformin hydrochloride 💬 Metformin [31] 2, 6, 8, 13, 46, 49, 60, 65, 66, 67, 74, 75, 77, 81, 84, 85, 86, 97, 113, 127, 158, 206, 218, 222, 225, 233, 265, 285, 298, 299, 301 💬
376 PRKAA2 💬 [20] FoxO signaling pathway, Autophagy - animal, mTOR signaling pathway, PI3K-Akt signaling pathway, AMPK signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Apelin signaling pathway, Tight junction, Circadian rhythm, Thermogenesis, Insulin signaling pathway, Adipocytokine signaling pathway, Oxytocin signaling pathway, Glucagon signaling pathway, Insulin resistance, Non-alcoholic fatty liver disease, Alcoholic liver disease, Hypertrophic cardiomyopathy, Fluid shear stress and atherosclerosis Metformin 💬 Metformin [31] 2, 6, 8, 13, 46, 49, 60, 65, 66, 67, 74, 75, 77, 81, 84, 85, 86, 97, 113, 127, 158, 206, 218, 222, 225, 233, 265, 285, 298, 299, 301 💬
377 PRKAA2 💬 [20] FoxO signaling pathway, Autophagy - animal, mTOR signaling pathway, PI3K-Akt signaling pathway, AMPK signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Apelin signaling pathway, Tight junction, Circadian rhythm, Thermogenesis, Insulin signaling pathway, Adipocytokine signaling pathway, Oxytocin signaling pathway, Glucagon signaling pathway, Insulin resistance, Non-alcoholic fatty liver disease, Alcoholic liver disease, Hypertrophic cardiomyopathy, Fluid shear stress and atherosclerosis Metformin hydrochloride 💬 Metformin [31] 2, 6, 8, 13, 46, 49, 60, 65, 66, 67, 74, 75, 77, 81, 84, 85, 86, 97, 113, 127, 158, 206, 218, 222, 225, 233, 265, 285, 298, 299, 301 💬
378 PTGIR 💬 [3] Neuroactive ligand-receptor interaction, Vascular smooth muscle contraction, Platelet activation Ibudilast 💬 Ibudilast [2] 2, 13 💬
379 PTGS2 💬 [22] Arachidonic acid metabolism, NF-kappa B signaling pathway, Efferocytosis, VEGF signaling pathway, C-type lectin receptor signaling pathway, IL-17 signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Ovarian steroidogenesis, Oxytocin signaling pathway, Regulation of lipolysis in adipocytes, Alzheimer disease, Pathways of neurodegeneration - multiple diseases, Leishmaniasis, Human cytomegalovirus infection, Human papillomavirus infection, Kaposi sarcoma-associated herpesvirus infection, Pathways in cancer, Chemical carcinogenesis - DNA adducts, MicroRNAs in cancer, Small cell lung cancer Celecoxib 💬 Celecoxib [14] 2, 3, 6, 13, 34, 46, 70, 89, 96, 97, 107, 161, 171, 271 💬
380 RARA 💬 [5] Th17 cell differentiation, Estrogen signaling pathway, Pathways in cancer, Transcriptional misregulation in cancer, Acute myeloid leukemia Tretinoin 💬 Tretinoin [4] 2, 62, 63, 75 💬
381 RARB 💬 [4] Pathways in cancer, Small cell lung cancer, Non-small cell lung cancer, Gastric cancer Tretinoin 💬 Tretinoin [4] 2, 62, 63, 75 💬
382 ROCK1 💬 [22] cGMP-PKG signaling pathway, cAMP signaling pathway, Chemokine signaling pathway, Sphingolipid signaling pathway, Vascular smooth muscle contraction, TGF-beta signaling pathway, Axon guidance, Focal adhesion, Cadherin signaling, Adherens junction, Tight junction, Platelet activation, Leukocyte transendothelial migration, Regulation of actin cytoskeleton, Oxytocin signaling pathway, Pathogenic Escherichia coli infection, Shigellosis, Yersinia infection, Human cytomegalovirus infection, Pathways in cancer, Proteoglycans in cancer, MicroRNAs in cancer Fasudil hydrochloride 💬 Fasudil [5] 2, 5, 6, 7, 51 💬
383 ROCK1 💬 [22] cGMP-PKG signaling pathway, cAMP signaling pathway, Chemokine signaling pathway, Sphingolipid signaling pathway, Vascular smooth muscle contraction, TGF-beta signaling pathway, Axon guidance, Focal adhesion, Cadherin signaling, Adherens junction, Tight junction, Platelet activation, Leukocyte transendothelial migration, Regulation of actin cytoskeleton, Oxytocin signaling pathway, Pathogenic Escherichia coli infection, Shigellosis, Yersinia infection, Human cytomegalovirus infection, Pathways in cancer, Proteoglycans in cancer, MicroRNAs in cancer Fasudil 💬 Fasudil [5] 2, 5, 6, 7, 51 💬
384 ROCK2 💬 [23] cGMP-PKG signaling pathway, cAMP signaling pathway, Chemokine signaling pathway, Sphingolipid signaling pathway, Vascular smooth muscle contraction, Wnt signaling pathway, Axon guidance, Focal adhesion, Cadherin signaling, Adherens junction, Tight junction, Platelet activation, Leukocyte transendothelial migration, Regulation of actin cytoskeleton, Oxytocin signaling pathway, Pathogenic Escherichia coli infection, Shigellosis, Salmonella infection, Yersinia infection, Human cytomegalovirus infection, Pathways in cancer, Proteoglycans in cancer, Lipid and atherosclerosis Fasudil hydrochloride 💬 Fasudil [5] 2, 5, 6, 7, 51 💬
385 ROCK2 💬 [23] cGMP-PKG signaling pathway, cAMP signaling pathway, Chemokine signaling pathway, Sphingolipid signaling pathway, Vascular smooth muscle contraction, Wnt signaling pathway, Axon guidance, Focal adhesion, Cadherin signaling, Adherens junction, Tight junction, Platelet activation, Leukocyte transendothelial migration, Regulation of actin cytoskeleton, Oxytocin signaling pathway, Pathogenic Escherichia coli infection, Shigellosis, Salmonella infection, Yersinia infection, Human cytomegalovirus infection, Pathways in cancer, Proteoglycans in cancer, Lipid and atherosclerosis Fasudil 💬 Fasudil [5] 2, 5, 6, 7, 51 💬
386 RTN4 💬 [1] Alzheimer disease Ozanezumab 💬 Ozanezumab [1] 2 💬
387 SCN1A 💬 [1] Dopaminergic synapse Quinidine gluconate 💬 Quinidine [3] 2, 8, 13 💬
388 SCN1A 💬 [1] Dopaminergic synapse Quinidine polygalacturonate 💬 Quinidine [3] 2, 8, 13 💬
389 SCN1A 💬 [1] Dopaminergic synapse Quinidine 💬 Quinidine [3] 2, 8, 13 💬
390 SCN1A 💬 [1] Dopaminergic synapse Mexiletine hydrochloride 💬 Mexiletine [6] 1, 2, 10, 113, 114, 115 💬
391 SCN1A 💬 [1] Dopaminergic synapse Quinidine sulfate 💬 Quinidine [3] 2, 8, 13 💬
392 SCN1A 💬 [1] Dopaminergic synapse Mexiletine 💬 Mexiletine [6] 1, 2, 10, 113, 114, 115 💬
393 SCN2A 💬 [1] Taste transduction Quinidine sulfate 💬 Quinidine [3] 2, 8, 13 💬
394 SCN2A 💬 [1] Taste transduction Quinidine gluconate 💬 Quinidine [3] 2, 8, 13 💬
395 SCN2A 💬 [1] Taste transduction Quinidine polygalacturonate 💬 Quinidine [3] 2, 8, 13 💬
396 SCN2A 💬 [1] Taste transduction Quinidine 💬 Quinidine [3] 2, 8, 13 💬
397 SCN2A 💬 [1] Taste transduction Mexiletine 💬 Mexiletine [6] 1, 2, 10, 113, 114, 115 💬
398 SCN2A 💬 [1] Taste transduction Mexiletine hydrochloride 💬 Mexiletine [6] 1, 2, 10, 113, 114, 115 💬
399 SCN3A 💬 [1] Taste transduction Quinidine 💬 Quinidine [3] 2, 8, 13 💬
400 SCN3A 💬 [1] Taste transduction Quinidine sulfate 💬 Quinidine [3] 2, 8, 13 💬
401 SCN3A 💬 [1] Taste transduction Mexiletine 💬 Mexiletine [6] 1, 2, 10, 113, 114, 115 💬
402 SCN3A 💬 [1] Taste transduction Quinidine gluconate 💬 Quinidine [3] 2, 8, 13 💬
403 SCN3A 💬 [1] Taste transduction Lacosamide 💬 Lacosamide [4] 2, 46, 149, 298 💬
404 SCN3A 💬 [1] Taste transduction Quinidine polygalacturonate 💬 Quinidine [3] 2, 8, 13 💬
405 SCN3A 💬 [1] Taste transduction Mexiletine hydrochloride 💬 Mexiletine [6] 1, 2, 10, 113, 114, 115 💬
406 SCN5A 💬 [2] Adrenergic signaling in cardiomyocytes, Cadherin signaling Quinidine 💬 Quinidine [3] 2, 8, 13 💬
407 SCN5A 💬 [2] Adrenergic signaling in cardiomyocytes, Cadherin signaling Mexiletine 💬 Mexiletine [6] 1, 2, 10, 113, 114, 115 💬
408 SCN5A 💬 [2] Adrenergic signaling in cardiomyocytes, Cadherin signaling Quinidine gluconate 💬 Quinidine [3] 2, 8, 13 💬
409 SCN5A 💬 [2] Adrenergic signaling in cardiomyocytes, Cadherin signaling Quinidine sulfate 💬 Quinidine [3] 2, 8, 13 💬
410 SCN5A 💬 [2] Adrenergic signaling in cardiomyocytes, Cadherin signaling Quinidine polygalacturonate 💬 Quinidine [3] 2, 8, 13 💬
411 SCN5A 💬 [2] Adrenergic signaling in cardiomyocytes, Cadherin signaling Mexiletine hydrochloride 💬 Mexiletine [6] 1, 2, 10, 113, 114, 115 💬
412 SCN8A 💬 [1] IgSF CAM signaling Quinidine gluconate 💬 Quinidine [3] 2, 8, 13 💬
413 SCN8A 💬 [1] IgSF CAM signaling Mexiletine hydrochloride 💬 Mexiletine [6] 1, 2, 10, 113, 114, 115 💬
414 SCN8A 💬 [1] IgSF CAM signaling Quinidine sulfate 💬 Quinidine [3] 2, 8, 13 💬
415 SCN8A 💬 [1] IgSF CAM signaling Quinidine 💬 Quinidine [3] 2, 8, 13 💬
416 SCN8A 💬 [1] IgSF CAM signaling Mexiletine 💬 Mexiletine [6] 1, 2, 10, 113, 114, 115 💬
417 SCN8A 💬 [1] IgSF CAM signaling Quinidine polygalacturonate 💬 Quinidine [3] 2, 8, 13 💬
418 SCN9A 💬 [1] Taste transduction Quinidine gluconate 💬 Quinidine [3] 2, 8, 13 💬
419 SCN9A 💬 [1] Taste transduction Mexiletine hydrochloride 💬 Mexiletine [6] 1, 2, 10, 113, 114, 115 💬
420 SCN9A 💬 [1] Taste transduction Quinidine 💬 Quinidine [3] 2, 8, 13 💬
421 SCN9A 💬 [1] Taste transduction Lacosamide 💬 Lacosamide [4] 2, 46, 149, 298 💬
422 SCN9A 💬 [1] Taste transduction Quinidine polygalacturonate 💬 Quinidine [3] 2, 8, 13 💬
423 SCN9A 💬 [1] Taste transduction Quinidine sulfate 💬 Quinidine [3] 2, 8, 13 💬
424 SCN9A 💬 [1] Taste transduction Mexiletine 💬 Mexiletine [6] 1, 2, 10, 113, 114, 115 💬
425 SIGMAR1 💬 [2] Amyotrophic lateral sclerosis, Pathways of neurodegeneration - multiple diseases Dextromethorphan hydrobromide 💬 Dextromethorphan [10] 2, 6, 8, 13, 21, 46, 85, 96, 97, 156 💬
426 SIGMAR1 💬 [2] Amyotrophic lateral sclerosis, Pathways of neurodegeneration - multiple diseases Dextromethorphan 💬 Dextromethorphan [10] 2, 6, 8, 13, 21, 46, 85, 96, 97, 156 💬
427 SIGMAR1 💬 [2] Amyotrophic lateral sclerosis, Pathways of neurodegeneration - multiple diseases Dextromethorphan polistirex 💬 Dextromethorphan [10] 2, 6, 8, 13, 21, 46, 85, 96, 97, 156 💬
428 SLC6A4 💬 [3] Neuroactive ligand signaling, Synaptic vesicle cycle, Serotonergic synapse Escitalopram 💬 Escitalopram [5] 2, 6, 13, 46, 77 💬
429 SLC6A4 💬 [3] Neuroactive ligand signaling, Synaptic vesicle cycle, Serotonergic synapse Trazodone hydrochloride 💬 Trazodone [1] 2 💬
430 SLC6A4 💬 [3] Neuroactive ligand signaling, Synaptic vesicle cycle, Serotonergic synapse Escitalopram oxalate 💬 Escitalopram [5] 2, 6, 13, 46, 77 💬
431 SLC6A4 💬 [3] Neuroactive ligand signaling, Synaptic vesicle cycle, Serotonergic synapse Trazodone 💬 Trazodone [1] 2 💬
432 SNAP25 💬 [2] Synaptic vesicle cycle, Insulin secretion Incobotulinumtoxin A 💬 Botulinum toxin type A [13] 2, 5, 6, 7, 13, 15, 17, 47, 70, 113, 149, 171, 226 💬
433 SNAP25 💬 [2] Synaptic vesicle cycle, Insulin secretion RimabotulinumtoxinB 💬 Botulinum toxin type B [3] 2, 6, 51 💬
434 SNAP25 💬 [2] Synaptic vesicle cycle, Insulin secretion Botulinum toxin type A 💬 Botulinum toxin type A [13] 2, 5, 6, 7, 13, 15, 17, 47, 70, 113, 149, 171, 226 💬
435 SOD1 💬 [8] Peroxisome, Longevity regulating pathway - multiple species, Parkinson disease, Amyotrophic lateral sclerosis, Huntington disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Chemical carcinogenesis - reactive oxygen species Tofersen 💬 Tofersen [1] 2 💬
436 SRC 💬 [43] ErbB signaling pathway, Rap1 signaling pathway, Chemokine signaling pathway, Hormone signaling, Mitophagy - animal, Endocytosis, Axon guidance, VEGF signaling pathway, Focal adhesion, IgSF CAM signaling, Integrin signaling, Adherens junction, Tight junction, Gap junction, Platelet activation, Neutrophil extracellular trap formation, C-type lectin receptor signaling pathway, GABAergic synapse, Inflammatory mediator regulation of TRP channels, Regulation of actin cytoskeleton, GnRH signaling pathway, Estrogen signaling pathway, Prolactin signaling pathway, Thyroid hormone signaling pathway, Oxytocin signaling pathway, Relaxin signaling pathway, Bacterial invasion of epithelial cells, Epithelial cell signaling in Helicobacter pylori infection, Pathogenic Escherichia coli infection, Shigellosis, Yersinia infection, Tuberculosis, Hepatitis B, Human cytomegalovirus infection, Kaposi sarcoma-associated herpesvirus infection, Herpes simplex virus 1 infection, Viral carcinogenesis, Proteoglycans in cancer, Chemical carcinogenesis - receptor activation, Chemical carcinogenesis - reactive oxygen species, Bladder cancer, Lipid and atherosclerosis, Fluid shear stress and atherosclerosis Bosutinib hydrate 💬 Bosutinib [2] 2, 67 💬
437 SRC 💬 [43] ErbB signaling pathway, Rap1 signaling pathway, Chemokine signaling pathway, Hormone signaling, Mitophagy - animal, Endocytosis, Axon guidance, VEGF signaling pathway, Focal adhesion, IgSF CAM signaling, Integrin signaling, Adherens junction, Tight junction, Gap junction, Platelet activation, Neutrophil extracellular trap formation, C-type lectin receptor signaling pathway, GABAergic synapse, Inflammatory mediator regulation of TRP channels, Regulation of actin cytoskeleton, GnRH signaling pathway, Estrogen signaling pathway, Prolactin signaling pathway, Thyroid hormone signaling pathway, Oxytocin signaling pathway, Relaxin signaling pathway, Bacterial invasion of epithelial cells, Epithelial cell signaling in Helicobacter pylori infection, Pathogenic Escherichia coli infection, Shigellosis, Yersinia infection, Tuberculosis, Hepatitis B, Human cytomegalovirus infection, Kaposi sarcoma-associated herpesvirus infection, Herpes simplex virus 1 infection, Viral carcinogenesis, Proteoglycans in cancer, Chemical carcinogenesis - receptor activation, Chemical carcinogenesis - reactive oxygen species, Bladder cancer, Lipid and atherosclerosis, Fluid shear stress and atherosclerosis Bosutinib 💬 Bosutinib [2] 2, 67 💬
438 SRD5A1 💬 [1] Steroid hormone biosynthesis Dutasteride 💬 Dutasteride [2] 1, 2 💬
439 SRD5A2 💬 [2] Steroid hormone biosynthesis, Prostate cancer Dutasteride 💬 Dutasteride [2] 1, 2 💬
440 SV2A 💬 [1] ECM-receptor interaction Levetiracetam 💬 Levetiracetam [7] 2, 4, 6, 13, 34, 149, 307 💬
441 TGFBR1 💬 [23] MAPK signaling pathway, Cytokine-cytokine receptor interaction, FoxO signaling pathway, Endocytosis, Cellular senescence, TGF-beta signaling pathway, Apelin signaling pathway, Osteoclast differentiation, Hippo signaling pathway, Adherens junction, Th17 cell differentiation, Relaxin signaling pathway, AGE-RAGE signaling pathway in diabetic complications, Chagas disease, Hepatitis B, Human T-cell leukemia virus 1 infection, Pathways in cancer, Colorectal cancer, Pancreatic cancer, Chronic myeloid leukemia, Hepatocellular carcinoma, Gastric cancer, Diabetic cardiomyopathy Galunisertib 💬 Galunisertib [1] 2 💬
442 TNF 💬 [66] MAPK signaling pathway, Cytokine-cytokine receptor interaction, Viral protein interaction with cytokine and cytokine receptor, NF-kappa B signaling pathway, Sphingolipid signaling pathway, mTOR signaling pathway, Apoptosis, Necroptosis, TGF-beta signaling pathway, Osteoclast differentiation, Antigen processing and presentation, Toll-like receptor signaling pathway, NOD-like receptor signaling pathway, RIG-I-like receptor signaling pathway, C-type lectin receptor signaling pathway, Hematopoietic cell lineage, Natural killer cell mediated cytotoxicity, IL-17 signaling pathway, T cell receptor signaling pathway, Fc epsilon RI signaling pathway, TNF signaling pathway, Adipocytokine signaling pathway, Type II diabetes mellitus, Insulin resistance, Non-alcoholic fatty liver disease, AGE-RAGE signaling pathway in diabetic complications, Alcoholic liver disease, Type I diabetes mellitus, Alzheimer disease, Amyotrophic lateral sclerosis, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Shigellosis, Salmonella infection, Pertussis, Legionellosis, Yersinia infection, Leishmaniasis, Chagas disease, African trypanosomiasis, Malaria, Toxoplasmosis, Amoebiasis, Tuberculosis, Hepatitis C, Hepatitis B, Human cytomegalovirus infection, Influenza A, Human papillomavirus infection, Human T-cell leukemia virus 1 infection, Herpes simplex virus 1 infection, Epstein-Barr virus infection, Human immunodeficiency virus 1 infection, Coronavirus disease, Proteoglycans in cancer, Asthma, Inflammatory bowel disease, Systemic lupus erythematosus, Rheumatoid arthritis, Allograft rejection, Graft-versus-host disease, Hypertrophic cardiomyopathy, Dilated cardiomyopathy, Lipid and atherosclerosis, Fluid shear stress and atherosclerosis Thalidomide 💬 Thalidomide [22] 2, 16, 20, 28, 49, 51, 53, 56, 63, 65, 84, 85, 94, 96, 97, 117, 227, 271, 280, 298, 300, 331 💬
443 TNNC2 💬 [3] Calcium signaling pathway, Motor proteins, Cytoskeleton in muscle cells Reldesemtiv 💬 Reldesemtiv [2] 2, 3 💬
444 TNNI2 💬 [2] Motor proteins, Cytoskeleton in muscle cells Reldesemtiv 💬 Reldesemtiv [2] 2, 3 💬
445 TNNT3 💬 [2] Motor proteins, Cytoskeleton in muscle cells Reldesemtiv 💬 Reldesemtiv [2] 2, 3 💬
446 TRPV1 💬 [2] Neuroactive ligand-receptor interaction, Inflammatory mediator regulation of TRP channels Capsaicin 💬 Capsaicin [5] 2, 6, 19, 86, 226 💬
447 TUBB 💬 [12] Phagocytosis, IgSF CAM signaling, Gap junction, Motor proteins, Alzheimer disease, Parkinson disease, Amyotrophic lateral sclerosis, Huntington disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection Colchicine 💬 Colchicine [9] 2, 42, 46, 50, 56, 93, 97, 210, 266 💬
448 TUBB1 💬 [12] Phagocytosis, IgSF CAM signaling, Gap junction, Motor proteins, Alzheimer disease, Parkinson disease, Amyotrophic lateral sclerosis, Huntington disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection Colchicine 💬 Colchicine [9] 2, 42, 46, 50, 56, 93, 97, 210, 266 💬
449 TUBB2A 💬 [12] Phagocytosis, IgSF CAM signaling, Gap junction, Motor proteins, Alzheimer disease, Parkinson disease, Amyotrophic lateral sclerosis, Huntington disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection Colchicine 💬 Colchicine [9] 2, 42, 46, 50, 56, 93, 97, 210, 266 💬
450 TUBB2B 💬 [12] Phagocytosis, IgSF CAM signaling, Gap junction, Motor proteins, Alzheimer disease, Parkinson disease, Amyotrophic lateral sclerosis, Huntington disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection Colchicine 💬 Colchicine [9] 2, 42, 46, 50, 56, 93, 97, 210, 266 💬
451 TUBB3 💬 [12] Phagocytosis, IgSF CAM signaling, Gap junction, Motor proteins, Alzheimer disease, Parkinson disease, Amyotrophic lateral sclerosis, Huntington disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection Colchicine 💬 Colchicine [9] 2, 42, 46, 50, 56, 93, 97, 210, 266 💬
452 TUBB4A 💬 [12] Phagocytosis, IgSF CAM signaling, Gap junction, Motor proteins, Alzheimer disease, Parkinson disease, Amyotrophic lateral sclerosis, Huntington disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection Colchicine 💬 Colchicine [9] 2, 42, 46, 50, 56, 93, 97, 210, 266 💬
453 TUBB4B 💬 [12] Phagocytosis, IgSF CAM signaling, Gap junction, Motor proteins, Alzheimer disease, Parkinson disease, Amyotrophic lateral sclerosis, Huntington disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection Colchicine 💬 Colchicine [9] 2, 42, 46, 50, 56, 93, 97, 210, 266 💬
454 TUBB6 💬 [12] Phagocytosis, IgSF CAM signaling, Gap junction, Motor proteins, Alzheimer disease, Parkinson disease, Amyotrophic lateral sclerosis, Huntington disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection Colchicine 💬 Colchicine [9] 2, 42, 46, 50, 56, 93, 97, 210, 266 💬
455 TUBB8 💬 [12] Phagocytosis, IgSF CAM signaling, Gap junction, Motor proteins, Alzheimer disease, Parkinson disease, Amyotrophic lateral sclerosis, Huntington disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection Colchicine 💬 Colchicine [9] 2, 42, 46, 50, 56, 93, 97, 210, 266 💬
456 TYK2 💬 [17] Necroptosis, Osteoclast differentiation, Toll-like receptor signaling pathway, NOD-like receptor signaling pathway, JAK-STAT signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Hepatitis C, Hepatitis B, Measles, Influenza A, Human papillomavirus infection, Kaposi sarcoma-associated herpesvirus infection, Herpes simplex virus 1 infection, Epstein-Barr virus infection, Coronavirus disease Tofacitinib 💬 Tofacitinib [23] 2, 11, 35, 38, 39, 40, 44, 46, 49, 50, 51, 53, 56, 65, 66, 84, 96, 97, 107, 110, 162, 271, 300 💬
457 TYK2 💬 [17] Necroptosis, Osteoclast differentiation, Toll-like receptor signaling pathway, NOD-like receptor signaling pathway, JAK-STAT signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Hepatitis C, Hepatitis B, Measles, Influenza A, Human papillomavirus infection, Kaposi sarcoma-associated herpesvirus infection, Herpes simplex virus 1 infection, Epstein-Barr virus infection, Coronavirus disease Tofacitinib citrate 💬 Tofacitinib [23] 2, 11, 35, 38, 39, 40, 44, 46, 49, 50, 51, 53, 56, 65, 66, 84, 96, 97, 107, 110, 162, 271, 300 💬
458 XDH 💬 [4] Purine metabolism, Caffeine metabolism, Drug metabolism - other enzymes, Peroxisome Febuxostat 💬 Febuxostat [5] 2, 6, 13, 67, 97 💬
459 XDH 💬 [4] Purine metabolism, Caffeine metabolism, Drug metabolism - other enzymes, Peroxisome Febuxostat hydrate 💬 Febuxostat [5] 2, 6, 13, 67, 97 💬