Target Gene/Pathway Pathway / Gene

  

Search results

No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank Disease ID
1 ADORA1 [2] Sphingolipid signaling pathway, Renin secretion D00045 Adenosine [3] 13, 58, 65
2 ADORA1 [2] Sphingolipid signaling pathway, Renin secretion D00227 Aminophylline [1] 63
3 ADORA1 [2] Sphingolipid signaling pathway, Renin secretion D00371 Theophylline [2] 236, 299
4 ADORA1 [2] Sphingolipid signaling pathway, Renin secretion D00528 Caffeine [8] 2, 6, 21, 46, 78, 96, 97, 265
5 ADORA1 [2] Sphingolipid signaling pathway, Renin secretion D01453 Caffeine [8] 2, 6, 21, 46, 78, 96, 97, 265
6 ADORA1 [2] Sphingolipid signaling pathway, Renin secretion D02769 Adenosine phosphate [1] 46
7 ADORA1 [2] Sphingolipid signaling pathway, Renin secretion D06103 Theophylline [2] 236, 299
8 ADRB1 [2] Renin secretion, Salivary secretion D00076 Norepinephrine [2] 22, 296
9 ADRB1 [2] Renin secretion, Salivary secretion D00095 Epinephrine [3] 46, 70, 96
10 ADRB1 [2] Renin secretion, Salivary secretion D00124 Ephedrine [1] 11
11 ADRB1 [2] Renin secretion, Salivary secretion D00235 Atenolol [1] 167
12 ADRB1 [2] Renin secretion, Salivary secretion D00255 Carvedilol [4] 57, 86, 113, 210
13 ADRB1 [2] Renin secretion, Salivary secretion D00378 Timolol [2] 157, 227
14 ADRB1 [2] Renin secretion, Salivary secretion D00432 Nadolol [1] 6
15 ADRB1 [2] Renin secretion, Salivary secretion D01277 Droxidopa [5] 5, 6, 17, 169, 170
16 ADRB1 [2] Renin secretion, Salivary secretion D02342 Bisoprolol [4] 58, 67, 86, 113
17 ADRB1 [2] Renin secretion, Salivary secretion D02349 Dipivefrin [1] 6
18 ADRB1 [2] Renin secretion, Salivary secretion D02358 Metoprolol [6] 17, 57, 58, 113, 193, 226
19 ADRB1 [2] Renin secretion, Salivary secretion D02910 Amiodarone [2] 28, 127
20 ADRB1 [2] Renin secretion, Salivary secretion D03879 Dobutamine [4] 57, 58, 86, 215
21 ADRB1 [2] Renin secretion, Salivary secretion D05127 Nebivolol [4] 17, 85, 113, 167
22 ADRB1 [2] Renin secretion, Salivary secretion D07660 Celiprolol [1] 168
23 ADRB1 [2] Renin secretion, Salivary secretion D07916 Esmolol [1] 58
24 ADRB1 [2] Renin secretion, Salivary secretion D08443 Propranolol [6] 6, 158, 167, 227, 278, 296
25 ADRB1 [2] Renin secretion, Salivary secretion D08449 Pseudoephedrine [1] 17
26 ADRB1 [2] Renin secretion, Salivary secretion D08600 Timolol [2] 157, 227
27 ADRB2 [2] Renin secretion, Salivary secretion D00076 Norepinephrine [2] 22, 296
28 ADRB2 [2] Renin secretion, Salivary secretion D00095 Epinephrine [3] 46, 70, 96
29 ADRB2 [2] Renin secretion, Salivary secretion D00124 Ephedrine [1] 11
30 ADRB2 [2] Renin secretion, Salivary secretion D00255 Carvedilol [4] 57, 86, 113, 210
31 ADRB2 [2] Renin secretion, Salivary secretion D00378 Timolol [2] 157, 227
32 ADRB2 [2] Renin secretion, Salivary secretion D00432 Nadolol [1] 6
33 ADRB2 [2] Renin secretion, Salivary secretion D01277 Droxidopa [5] 5, 6, 17, 169, 170
34 ADRB2 [2] Renin secretion, Salivary secretion D02147 Salbutamol [12] 3, 11, 12, 13, 49, 85, 86, 89, 111, 113, 256, 299
35 ADRB2 [2] Renin secretion, Salivary secretion D02151 Tulobuterol [1] 6
36 ADRB2 [2] Renin secretion, Salivary secretion D02349 Dipivefrin [1] 6
37 ADRB2 [2] Renin secretion, Salivary secretion D05792 Salmeterol [1] 299
38 ADRB2 [2] Renin secretion, Salivary secretion D07713 Clenbuterol [5] 1, 2, 6, 13, 256
39 ADRB2 [2] Renin secretion, Salivary secretion D07990 Formoterol [3] 85, 228, 299
40 ADRB2 [2] Renin secretion, Salivary secretion D08092 Isoxsuprine [1] 13
41 ADRB2 [2] Renin secretion, Salivary secretion D08124 Levosalbutamol [1] 49
42 ADRB2 [2] Renin secretion, Salivary secretion D08443 Propranolol [6] 6, 158, 167, 227, 278, 296
43 ADRB2 [2] Renin secretion, Salivary secretion D08449 Pseudoephedrine [1] 17
44 ADRB2 [2] Renin secretion, Salivary secretion D08570 Terbutaline [1] 118
45 ADRB2 [2] Renin secretion, Salivary secretion D08600 Timolol [2] 157, 227
46 ADRB3 [3] Thermogenesis, Renin secretion, Salivary secretion D00076 Norepinephrine [2] 22, 296
47 ADRB3 [3] Thermogenesis, Renin secretion, Salivary secretion D00095 Epinephrine [3] 46, 70, 96
48 ADRB3 [3] Thermogenesis, Renin secretion, Salivary secretion D00124 Ephedrine [1] 11
49 ADRB3 [3] Thermogenesis, Renin secretion, Salivary secretion D01277 Droxidopa [5] 5, 6, 17, 169, 170
50 ADRB3 [3] Thermogenesis, Renin secretion, Salivary secretion D02349 Dipivefrin [1] 6
51 ADRB3 [3] Thermogenesis, Renin secretion, Salivary secretion D08443 Propranolol [6] 6, 158, 167, 227, 278, 296
52 ADRB3 [3] Thermogenesis, Renin secretion, Salivary secretion D08449 Pseudoephedrine [1] 17
53 ADRB3 [3] Thermogenesis, Renin secretion, Salivary secretion D09535 Mirabegron [4] 6, 13, 53, 226
54 ACE [2] Renin-angiotensin system, Renin secretion D00251 Captopril [8] 6, 17, 46, 86, 96, 97, 107, 271
55 ACE [2] Renin-angiotensin system, Renin secretion D00362 Lisinopril [7] 19, 46, 49, 66, 67, 113, 222
56 ACE [2] Renin-angiotensin system, Renin secretion D00421 Ramipril [7] 46, 49, 66, 67, 113, 218, 257
57 ACE [2] Renin-angiotensin system, Renin secretion D01069 Cilazapril [1] 66
58 ACE [2] Renin-angiotensin system, Renin secretion D03752 Quinapril [1] 19
59 ACE [2] Renin-angiotensin system, Renin secretion D03753 Perindopril [4] 58, 113, 167, 222
60 ACE [2] Renin-angiotensin system, Renin secretion D07499 Benazepril [4] 49, 57, 218, 224
61 ACE [2] Renin-angiotensin system, Renin secretion D07699 Cilazapril [1] 66
62 ACE [2] Renin-angiotensin system, Renin secretion D07892 Enalapril [6] 19, 46, 66, 113, 210, 222
63 ACE [2] Renin-angiotensin system, Renin secretion D08068 Imidapril [1] 67
64 ACE [2] Renin-angiotensin system, Renin secretion D08131 Lisinopril [7] 19, 46, 49, 66, 67, 113, 222
65 ACE [2] Renin-angiotensin system, Renin secretion D08225 Moexipril [1] 93
66 AGTR1 [3] Vascular smooth muscle contraction, Renin-angiotensin system, Renin secretion D00150 Angiotensin II [7] 17, 19, 46, 66, 86, 222, 224
67 AGTR1 [3] Vascular smooth muscle contraction, Renin-angiotensin system, Renin secretion D00400 Valsartan [7] 57, 58, 66, 75, 218, 222, 224
68 AGTR1 [3] Vascular smooth muscle contraction, Renin-angiotensin system, Renin secretion D00522 Candesartan [2] 58, 67
69 AGTR1 [3] Vascular smooth muscle contraction, Renin-angiotensin system, Renin secretion D00523 Irbesartan [4] 66, 167, 168, 222
70 AGTR1 [3] Vascular smooth muscle contraction, Renin-angiotensin system, Renin secretion D00626 Candesartan cilexetil [1] 67
71 AGTR1 [3] Vascular smooth muscle contraction, Renin-angiotensin system, Renin secretion D00627 Telmisartan [2] 66, 67
72 AGTR1 [3] Vascular smooth muscle contraction, Renin-angiotensin system, Renin secretion D02014 Angiotensin II [7] 17, 19, 46, 66, 86, 222, 224
73 AGTR1 [3] Vascular smooth muscle contraction, Renin-angiotensin system, Renin secretion D08146 Losartan [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299
74 AGTR1 [3] Vascular smooth muscle contraction, Renin-angiotensin system, Renin secretion D11776 Sparsentan [3] 66, 218, 222
75 EDNRA [2] Vascular smooth muscle contraction, Renin secretion D01227 Bosentan [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212
76 EDNRA [2] Vascular smooth muscle contraction, Renin secretion D07077 Ambrisentan [7] 51, 84, 85, 86, 88, 210, 211
77 EDNRA [2] Vascular smooth muscle contraction, Renin secretion D07171 Sitaxentan [1] 86
78 EDNRA [2] Vascular smooth muscle contraction, Renin secretion D07538 Bosentan [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212
79 EDNRA [2] Vascular smooth muscle contraction, Renin secretion D07741 Zibotentan [1] 51
80 EDNRA [2] Vascular smooth muscle contraction, Renin secretion D10135 Macitentan [5] 51, 85, 86, 88, 210
81 EDNRA [2] Vascular smooth muscle contraction, Renin secretion D11776 Sparsentan [3] 66, 218, 222
82 GUCY1A2 [3] Vascular smooth muscle contraction, Renin secretion, Salivary secretion D00517 Amyl Nitrite [1] 58
83 GUCY1A2 [3] Vascular smooth muscle contraction, Renin secretion, Salivary secretion D09572 Riociguat [6] 51, 84, 86, 88, 225, 299
84 GUCY1A1 [3] Vascular smooth muscle contraction, Renin secretion, Salivary secretion D00517 Amyl Nitrite [1] 58
85 GUCY1A1 [3] Vascular smooth muscle contraction, Renin secretion, Salivary secretion D09572 Riociguat [6] 51, 84, 86, 88, 225, 299
86 GUCY1B1 [3] Vascular smooth muscle contraction, Renin secretion, Salivary secretion D00517 Amyl Nitrite [1] 58
87 GUCY1B1 [3] Vascular smooth muscle contraction, Renin secretion, Salivary secretion D09572 Riociguat [6] 51, 84, 86, 88, 225, 299
88 NPR1 [3] Vascular smooth muscle contraction, Thermogenesis, Renin secretion D04051 Erythrityl tetranitrate [1] 46
89 NPR1 [3] Vascular smooth muscle contraction, Thermogenesis, Renin secretion D05147 Nesiritide [2] 46, 58
90 PDE1A [2] Taste transduction, Renin secretion D00227 Aminophylline [1] 63
91 PDE1A [2] Taste transduction, Renin secretion D00371 Theophylline [2] 236, 299
92 PDE1A [2] Taste transduction, Renin secretion D06103 Theophylline [2] 236, 299
93 PDE1A [2] Taste transduction, Renin secretion D07546 Bucladesine [1] 246
94 PDE1A [2] Taste transduction, Renin secretion D07961 Flavoxate [1] 226
95 PDE1C [2] Taste transduction, Renin secretion D00227 Aminophylline [1] 63
96 PDE1C [2] Taste transduction, Renin secretion D00371 Theophylline [2] 236, 299
97 PDE1C [2] Taste transduction, Renin secretion D06103 Theophylline [2] 236, 299
98 PDE1C [2] Taste transduction, Renin secretion D07546 Bucladesine [1] 246
99 PDE1C [2] Taste transduction, Renin secretion D07961 Flavoxate [1] 226
100 PDE3A [1] Renin secretion D00227 Aminophylline [1] 63
101 PDE3A [1] Renin secretion D00371 Theophylline [2] 236, 299
102 PDE3A [1] Renin secretion D00417 Milrinone [1] 294
103 PDE3A [1] Renin secretion D00528 Caffeine [8] 2, 6, 21, 46, 78, 96, 97, 265
104 PDE3A [1] Renin secretion D01385 Ibudilast [2] 2, 13
105 PDE3A [1] Renin secretion D01453 Caffeine [8] 2, 6, 21, 46, 78, 96, 97, 265
106 PDE3A [1] Renin secretion D01896 Cilostazol [3] 46, 51, 70
107 PDE3A [1] Renin secretion D04720 Levosimendan [1] 2
108 PDE3A [1] Renin secretion D06103 Theophylline [2] 236, 299
109 PDE3A [1] Renin secretion D07546 Bucladesine [1] 246
110 PDE3A [1] Renin secretion D07961 Flavoxate [1] 226
111 PDE3B [1] Renin secretion D00227 Aminophylline [1] 63
112 PDE3B [1] Renin secretion D00371 Theophylline [2] 236, 299
113 PDE3B [1] Renin secretion D00417 Milrinone [1] 294
114 PDE3B [1] Renin secretion D00528 Caffeine [8] 2, 6, 21, 46, 78, 96, 97, 265
115 PDE3B [1] Renin secretion D01385 Ibudilast [2] 2, 13
116 PDE3B [1] Renin secretion D01453 Caffeine [8] 2, 6, 21, 46, 78, 96, 97, 265
117 PDE3B [1] Renin secretion D01896 Cilostazol [3] 46, 51, 70
118 PDE3B [1] Renin secretion D04720 Levosimendan [1] 2
119 PDE3B [1] Renin secretion D06103 Theophylline [2] 236, 299
120 PDE3B [1] Renin secretion D07546 Bucladesine [1] 246
121 PDE3B [1] Renin secretion D07961 Flavoxate [1] 226
122 PDE1B [2] Taste transduction, Renin secretion D00227 Aminophylline [1] 63
123 PDE1B [2] Taste transduction, Renin secretion D00371 Theophylline [2] 236, 299
124 PDE1B [2] Taste transduction, Renin secretion D00528 Caffeine [8] 2, 6, 21, 46, 78, 96, 97, 265
125 PDE1B [2] Taste transduction, Renin secretion D01453 Caffeine [8] 2, 6, 21, 46, 78, 96, 97, 265
126 PDE1B [2] Taste transduction, Renin secretion D06103 Theophylline [2] 236, 299
127 PDE1B [2] Taste transduction, Renin secretion D07546 Bucladesine [1] 246
128 PDE1B [2] Taste transduction, Renin secretion D07961 Flavoxate [1] 226
129 PPP3CA [7] Wnt signaling pathway, VEGF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Renin secretion, Tuberculosis D00107 Tacrolimus [34] 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299
130 PPP3CA [7] Wnt signaling pathway, VEGF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Renin secretion, Tuberculosis D00184 Cyclosporine [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326
131 PPP3CA [7] Wnt signaling pathway, VEGF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Renin secretion, Tuberculosis D05480 Pimecrolimus [1] 160
132 PPP3CA [7] Wnt signaling pathway, VEGF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Renin secretion, Tuberculosis D08556 Tacrolimus [34] 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299
133 PPP3CA [7] Wnt signaling pathway, VEGF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Renin secretion, Tuberculosis D09033 Voclosporin [2] 49, 222
134 PPP3CB [7] Wnt signaling pathway, VEGF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Renin secretion, Tuberculosis D00107 Tacrolimus [34] 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299
135 PPP3CB [7] Wnt signaling pathway, VEGF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Renin secretion, Tuberculosis D00184 Cyclosporine [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326
136 PPP3CB [7] Wnt signaling pathway, VEGF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Renin secretion, Tuberculosis D05480 Pimecrolimus [1] 160
137 PPP3CB [7] Wnt signaling pathway, VEGF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Renin secretion, Tuberculosis D08556 Tacrolimus [34] 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299
138 PPP3CB [7] Wnt signaling pathway, VEGF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Renin secretion, Tuberculosis D09033 Voclosporin [2] 49, 222
139 PPP3CC [7] Wnt signaling pathway, VEGF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Renin secretion, Tuberculosis D00107 Tacrolimus [34] 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299
140 PPP3CC [7] Wnt signaling pathway, VEGF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Renin secretion, Tuberculosis D00184 Cyclosporine [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326
141 PPP3CC [7] Wnt signaling pathway, VEGF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Renin secretion, Tuberculosis D05480 Pimecrolimus [1] 160
142 PPP3CC [7] Wnt signaling pathway, VEGF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Renin secretion, Tuberculosis D08556 Tacrolimus [34] 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299
143 PPP3CC [7] Wnt signaling pathway, VEGF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Renin secretion, Tuberculosis D09033 Voclosporin [2] 49, 222
144 PPP3R1 [7] Wnt signaling pathway, VEGF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Renin secretion, Tuberculosis D00107 Tacrolimus [34] 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299
145 PPP3R1 [7] Wnt signaling pathway, VEGF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Renin secretion, Tuberculosis D00184 Cyclosporine [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326
146 PPP3R1 [7] Wnt signaling pathway, VEGF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Renin secretion, Tuberculosis D05480 Pimecrolimus [1] 160
147 PPP3R1 [7] Wnt signaling pathway, VEGF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Renin secretion, Tuberculosis D08556 Tacrolimus [34] 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299
148 PPP3R1 [7] Wnt signaling pathway, VEGF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Renin secretion, Tuberculosis D09033 Voclosporin [2] 49, 222
149 PPP3R2 [7] Wnt signaling pathway, VEGF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Renin secretion, Tuberculosis D00107 Tacrolimus [34] 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299
150 PPP3R2 [7] Wnt signaling pathway, VEGF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Renin secretion, Tuberculosis D00184 Cyclosporine [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326
151 PPP3R2 [7] Wnt signaling pathway, VEGF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Renin secretion, Tuberculosis D05480 Pimecrolimus [1] 160
152 PPP3R2 [7] Wnt signaling pathway, VEGF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Renin secretion, Tuberculosis D08556 Tacrolimus [34] 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299
153 PPP3R2 [7] Wnt signaling pathway, VEGF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Renin secretion, Tuberculosis D09033 Voclosporin [2] 49, 222
154 PTGER2 [1] Renin secretion D00419 Misoprostol [3] 46, 70, 271
155 PTGER4 [1] Renin secretion D00419 Misoprostol [3] 46, 70, 271
156 REN [2] Renin-angiotensin system, Renin secretion D03208 Aliskiren [3] 66, 167, 222
157 CACNA1C [6] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Renin secretion, Type II diabetes mellitus D00349 Isradipine [1] 6
158 CACNA1C [6] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Renin secretion, Type II diabetes mellitus D00437 Nifedipine [2] 50, 81
159 CACNA1C [6] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Renin secretion, Type II diabetes mellitus D00537 Topiramate [6] 6, 97, 140, 144, 156, 193
160 CACNA1C [6] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Renin secretion, Type II diabetes mellitus D01173 Cilnidipine [1] 67
161 CACNA1C [6] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Renin secretion, Type II diabetes mellitus D01908 Nilvadipine [1] 90
162 CACNA1C [6] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Renin secretion, Type II diabetes mellitus D02356 Verapamil [4] 58, 96, 140, 167
163 CACNA1C [6] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Renin secretion, Type II diabetes mellitus D07450 Amlodipine [4] 13, 51, 67, 298
164 CACNA1C [6] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Renin secretion, Type II diabetes mellitus D07845 Diltiazem [3] 51, 58, 86
165 CACNA1C [6] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Renin secretion, Type II diabetes mellitus D08270 Nicardipine [2] 70, 86
166 CACNA1C [6] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Renin secretion, Type II diabetes mellitus D08340 Perhexiline [2] 58, 272
167 CACNA1C [6] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Renin secretion, Type II diabetes mellitus D08441 Propiverine [1] 226
168 CACNA1D [6] Vascular smooth muscle contraction, Tight junction, Retrograde endocannabinoid signaling, Serotonergic synapse, Renin secretion, Type II diabetes mellitus D00349 Isradipine [1] 6
169 CACNA1D [6] Vascular smooth muscle contraction, Tight junction, Retrograde endocannabinoid signaling, Serotonergic synapse, Renin secretion, Type II diabetes mellitus D00437 Nifedipine [2] 50, 81
170 CACNA1D [6] Vascular smooth muscle contraction, Tight junction, Retrograde endocannabinoid signaling, Serotonergic synapse, Renin secretion, Type II diabetes mellitus D00537 Topiramate [6] 6, 97, 140, 144, 156, 193
171 CACNA1D [6] Vascular smooth muscle contraction, Tight junction, Retrograde endocannabinoid signaling, Serotonergic synapse, Renin secretion, Type II diabetes mellitus D01173 Cilnidipine [1] 67
172 CACNA1D [6] Vascular smooth muscle contraction, Tight junction, Retrograde endocannabinoid signaling, Serotonergic synapse, Renin secretion, Type II diabetes mellitus D01908 Nilvadipine [1] 90
173 CACNA1D [6] Vascular smooth muscle contraction, Tight junction, Retrograde endocannabinoid signaling, Serotonergic synapse, Renin secretion, Type II diabetes mellitus D02356 Verapamil [4] 58, 96, 140, 167
174 CACNA1D [6] Vascular smooth muscle contraction, Tight junction, Retrograde endocannabinoid signaling, Serotonergic synapse, Renin secretion, Type II diabetes mellitus D07450 Amlodipine [4] 13, 51, 67, 298
175 CACNA1D [6] Vascular smooth muscle contraction, Tight junction, Retrograde endocannabinoid signaling, Serotonergic synapse, Renin secretion, Type II diabetes mellitus D07845 Diltiazem [3] 51, 58, 86
176 CACNA1D [6] Vascular smooth muscle contraction, Tight junction, Retrograde endocannabinoid signaling, Serotonergic synapse, Renin secretion, Type II diabetes mellitus D08270 Nicardipine [2] 70, 86
177 CACNA1D [6] Vascular smooth muscle contraction, Tight junction, Retrograde endocannabinoid signaling, Serotonergic synapse, Renin secretion, Type II diabetes mellitus D08340 Perhexiline [2] 58, 272
178 CACNA1D [6] Vascular smooth muscle contraction, Tight junction, Retrograde endocannabinoid signaling, Serotonergic synapse, Renin secretion, Type II diabetes mellitus D08441 Propiverine [1] 226
179 CACNA1F [4] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Renin secretion D00349 Isradipine [1] 6
180 CACNA1F [4] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Renin secretion D00437 Nifedipine [2] 50, 81
181 CACNA1F [4] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Renin secretion D00537 Topiramate [6] 6, 97, 140, 144, 156, 193
182 CACNA1F [4] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Renin secretion D01173 Cilnidipine [1] 67
183 CACNA1F [4] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Renin secretion D01908 Nilvadipine [1] 90
184 CACNA1F [4] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Renin secretion D02356 Verapamil [4] 58, 96, 140, 167
185 CACNA1F [4] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Renin secretion D07450 Amlodipine [4] 13, 51, 67, 298
186 CACNA1F [4] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Renin secretion D07845 Diltiazem [3] 51, 58, 86
187 CACNA1F [4] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Renin secretion D08270 Nicardipine [2] 70, 86
188 CACNA1F [4] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Renin secretion D08340 Perhexiline [2] 58, 272
189 CACNA1F [4] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Renin secretion D08441 Propiverine [1] 226
190 CACNA1S [4] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Renin secretion D00349 Isradipine [1] 6
191 CACNA1S [4] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Renin secretion D00437 Nifedipine [2] 50, 81
192 CACNA1S [4] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Renin secretion D00537 Topiramate [6] 6, 97, 140, 144, 156, 193
193 CACNA1S [4] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Renin secretion D01173 Cilnidipine [1] 67
194 CACNA1S [4] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Renin secretion D01908 Nilvadipine [1] 90
195 CACNA1S [4] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Renin secretion D02356 Verapamil [4] 58, 96, 140, 167
196 CACNA1S [4] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Renin secretion D07450 Amlodipine [4] 13, 51, 67, 298
197 CACNA1S [4] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Renin secretion D07845 Diltiazem [3] 51, 58, 86
198 CACNA1S [4] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Renin secretion D08270 Nicardipine [2] 70, 86
199 CACNA1S [4] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Renin secretion D08340 Perhexiline [2] 58, 272
200 CACNA1S [4] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Renin secretion D08441 Propiverine [1] 226