Target Gene/Pathway Pathway / Gene

  

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No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank 指定難病告示番号
1 BDKRB2 💬 10件: Calcium signaling pathway, cGMP-PKG signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction, Complement and coagulation cascades, Inflammatory mediator regulation of TRP channels, Regulation of actin cytoskeleton, Endocrine and other factor-regulated calcium reabsorption, Chagas disease, Pathways in cancer Deucrictibant 💬 Deucrictibant 1件: 65 💬
2 BDKRB2 💬 10件: Calcium signaling pathway, cGMP-PKG signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction, Complement and coagulation cascades, Inflammatory mediator regulation of TRP channels, Regulation of actin cytoskeleton, Endocrine and other factor-regulated calcium reabsorption, Chagas disease, Pathways in cancer Icatibant acetate 💬 Icatibant 1件: 65 💬
3 C1R 💬 5件: Complement and coagulation cascades, Pertussis, Staphylococcus aureus infection, Coronavirus disease, Systemic lupus erythematosus Conestat alfa 💬 Conestat alfa 1件: 65 💬
4 C1S 💬 5件: Complement and coagulation cascades, Pertussis, Staphylococcus aureus infection, Coronavirus disease, Systemic lupus erythematosus Sutimlimab 💬 Sutimlimab 1件: 61 💬
5 C1S 💬 5件: Complement and coagulation cascades, Pertussis, Staphylococcus aureus infection, Coronavirus disease, Systemic lupus erythematosus Conestat alfa 💬 Conestat alfa 1件: 65 💬
6 C1S 💬 5件: Complement and coagulation cascades, Pertussis, Staphylococcus aureus infection, Coronavirus disease, Systemic lupus erythematosus Riliprubart 💬 Riliprubart 1件: 14 💬
7 C2 💬 6件: Complement and coagulation cascades, Alcoholic liver disease, Pertussis, Staphylococcus aureus infection, Coronavirus disease, Systemic lupus erythematosus Empasiprubart 💬 Empasiprubart 3件: 11, 14, 50 💬
8 C3 💬 18件: Neuroactive ligand-receptor interaction, Phagocytosis, Integrin signaling, Complement and coagulation cascades, Neutrophil extracellular trap formation, Alcoholic liver disease, Shigellosis, Pertussis, Legionellosis, Leishmaniasis, Chagas disease, Staphylococcus aureus infection, Tuberculosis, Kaposi sarcoma-associated herpesvirus infection, Herpes simplex virus 1 infection, Coronavirus disease, Viral carcinogenesis, Systemic lupus erythematosus Pegcetacoplan 💬 Pegcetacoplan 4件: 2, 61, 62, 223 💬
9 C5 💬 11件: Neuroactive ligand-receptor interaction, Complement and coagulation cascades, Neutrophil extracellular trap formation, Regulation of actin cytoskeleton, Alcoholic liver disease, Prion disease, Pertussis, Staphylococcus aureus infection, Herpes simplex virus 1 infection, Coronavirus disease, Systemic lupus erythematosus Vilobelimab 💬 Vilobelimab 3件: 43, 44, 269 💬
10 C5 💬 11件: Neuroactive ligand-receptor interaction, Complement and coagulation cascades, Neutrophil extracellular trap formation, Regulation of actin cytoskeleton, Alcoholic liver disease, Prion disease, Pertussis, Staphylococcus aureus infection, Herpes simplex virus 1 infection, Coronavirus disease, Systemic lupus erythematosus Zilucoplan 💬 Zilucoplan 3件: 2, 11, 62 💬
11 C5 💬 11件: Neuroactive ligand-receptor interaction, Complement and coagulation cascades, Neutrophil extracellular trap formation, Regulation of actin cytoskeleton, Alcoholic liver disease, Prion disease, Pertussis, Staphylococcus aureus infection, Herpes simplex virus 1 infection, Coronavirus disease, Systemic lupus erythematosus Nomacopan 💬 Nomacopan 1件: 162 💬
12 C5 💬 11件: Neuroactive ligand-receptor interaction, Complement and coagulation cascades, Neutrophil extracellular trap formation, Regulation of actin cytoskeleton, Alcoholic liver disease, Prion disease, Pertussis, Staphylococcus aureus infection, Herpes simplex virus 1 infection, Coronavirus disease, Systemic lupus erythematosus Pozelimab 💬 Pozelimab 3件: 11, 15, 62 💬
13 C5 💬 11件: Neuroactive ligand-receptor interaction, Complement and coagulation cascades, Neutrophil extracellular trap formation, Regulation of actin cytoskeleton, Alcoholic liver disease, Prion disease, Pertussis, Staphylococcus aureus infection, Herpes simplex virus 1 infection, Coronavirus disease, Systemic lupus erythematosus Avacincaptad pegol sodium 💬 Avacincaptad pegol 1件: 301 💬
14 C5 💬 11件: Neuroactive ligand-receptor interaction, Complement and coagulation cascades, Neutrophil extracellular trap formation, Regulation of actin cytoskeleton, Alcoholic liver disease, Prion disease, Pertussis, Staphylococcus aureus infection, Herpes simplex virus 1 infection, Coronavirus disease, Systemic lupus erythematosus Crovalimab 💬 Crovalimab 3件: 48, 62, 109 💬
15 C5 💬 11件: Neuroactive ligand-receptor interaction, Complement and coagulation cascades, Neutrophil extracellular trap formation, Regulation of actin cytoskeleton, Alcoholic liver disease, Prion disease, Pertussis, Staphylococcus aureus infection, Herpes simplex virus 1 infection, Coronavirus disease, Systemic lupus erythematosus Eculizumab 💬 Eculizumab 8件: 11, 13, 14, 61, 62, 109, 221, 223 💬
16 C5 💬 11件: Neuroactive ligand-receptor interaction, Complement and coagulation cascades, Neutrophil extracellular trap formation, Regulation of actin cytoskeleton, Alcoholic liver disease, Prion disease, Pertussis, Staphylococcus aureus infection, Herpes simplex virus 1 infection, Coronavirus disease, Systemic lupus erythematosus Ravulizumab 💬 Ravulizumab 8件: 2, 11, 13, 50, 62, 66, 109, 224 💬
17 C5 💬 11件: Neuroactive ligand-receptor interaction, Complement and coagulation cascades, Neutrophil extracellular trap formation, Regulation of actin cytoskeleton, Alcoholic liver disease, Prion disease, Pertussis, Staphylococcus aureus infection, Herpes simplex virus 1 infection, Coronavirus disease, Systemic lupus erythematosus Gefurulimab 💬 Gefurulimab 1件: 11 💬
18 C5 💬 11件: Neuroactive ligand-receptor interaction, Complement and coagulation cascades, Neutrophil extracellular trap formation, Regulation of actin cytoskeleton, Alcoholic liver disease, Prion disease, Pertussis, Staphylococcus aureus infection, Herpes simplex virus 1 infection, Coronavirus disease, Systemic lupus erythematosus Zilucoplan sodium 💬 Zilucoplan 3件: 2, 11, 62 💬
19 C5AR1 💬 6件: Neuroactive ligand-receptor interaction, Complement and coagulation cascades, Neutrophil extracellular trap formation, Alcoholic liver disease, Staphylococcus aureus infection, Coronavirus disease Avacopan 💬 Avacopan 4件: 43, 44, 66, 223 💬
20 CFB 💬 3件: Complement and coagulation cascades, Staphylococcus aureus infection, Coronavirus disease Iptacopan 💬 Iptacopan 8件: 11, 61, 62, 63, 66, 109, 222, 223 💬
21 CFB 💬 3件: Complement and coagulation cascades, Staphylococcus aureus infection, Coronavirus disease Iptacopan hydrochloride 💬 Iptacopan 8件: 11, 61, 62, 63, 66, 109, 222, 223 💬
22 CFD 💬 3件: Complement and coagulation cascades, Staphylococcus aureus infection, Coronavirus disease Danicopan 💬 Danicopan 2件: 62, 223 💬
23 F10 💬 1件: Complement and coagulation cascades Edoxaban tosylate 💬 Edoxaban 4件: 46, 71, 88, 222 💬
24 F10 💬 1件: Complement and coagulation cascades Edoxaban tosilate hydrate 💬 Edoxaban 4件: 46, 71, 88, 222 💬
25 F10 💬 1件: Complement and coagulation cascades Edoxaban 💬 Edoxaban 4件: 46, 71, 88, 222 💬
26 F10 💬 1件: Complement and coagulation cascades Emicizumab 💬 Emicizumab 1件: 288 💬
27 F10 💬 1件: Complement and coagulation cascades Apixaban 💬 Apixaban 6件: 48, 96, 97, 222, 223, 279 💬
28 F10 💬 1件: Complement and coagulation cascades Rivaroxaban 💬 Rivaroxaban 10件: 46, 48, 49, 56, 58, 75, 91, 210, 222, 271 💬
29 F12 💬 1件: Complement and coagulation cascades Garadacimab 💬 Garadacimab 2件: 65, 85 💬
30 F2 💬 8件: Phospholipase D signaling pathway, Neuroactive ligand-receptor interaction, Complement and coagulation cascades, Platelet activation, Regulation of actin cytoskeleton, Pathogenic Escherichia coli infection, Coronavirus disease, Pathways in cancer Dabigatran etexilate 💬 Dabigatran etexilate 2件: 51, 75 💬
31 F2 💬 8件: Phospholipase D signaling pathway, Neuroactive ligand-receptor interaction, Complement and coagulation cascades, Platelet activation, Regulation of actin cytoskeleton, Pathogenic Escherichia coli infection, Coronavirus disease, Pathways in cancer Thrombomodulin alfa 💬 Thrombomodulin Alfa 1件: 85 💬
32 F2 💬 8件: Phospholipase D signaling pathway, Neuroactive ligand-receptor interaction, Complement and coagulation cascades, Platelet activation, Regulation of actin cytoskeleton, Pathogenic Escherichia coli infection, Coronavirus disease, Pathways in cancer Dabigatran 💬 Dabigatran 5件: 51, 75, 85, 91, 124 💬
33 F2 💬 8件: Phospholipase D signaling pathway, Neuroactive ligand-receptor interaction, Complement and coagulation cascades, Platelet activation, Regulation of actin cytoskeleton, Pathogenic Escherichia coli infection, Coronavirus disease, Pathways in cancer Dabigatran etexilate mesylate 💬 Dabigatran etexilate 2件: 51, 75 💬
34 F8 💬 1件: Complement and coagulation cascades Susoctocog alfa 💬 Susoctocog alfa 1件: 288 💬
35 F8 💬 1件: Complement and coagulation cascades Desmopressin 💬 Desmopressin 8件: 6, 22, 64, 72, 75, 223, 225, 288 💬
36 F8 💬 1件: Complement and coagulation cascades Desmopressin acetate 💬 Desmopressin 8件: 6, 22, 64, 72, 75, 223, 225, 288 💬
37 F9 💬 1件: Complement and coagulation cascades Emicizumab 💬 Emicizumab 1件: 288 💬
38 ITGB2 💬 21件: Rap1 signaling pathway, Phagocytosis, Hippo signaling pathway, Cell adhesion molecule (CAM) interaction, IgSF CAM signaling, Integrin signaling, Complement and coagulation cascades, Neutrophil extracellular trap formation, Natural killer cell mediated cytotoxicity, Leukocyte transendothelial migration, Regulation of actin cytoskeleton, Pertussis, Legionellosis, Leishmaniasis, Malaria, Amoebiasis, Staphylococcus aureus infection, Tuberculosis, Human T-cell leukemia virus 1 infection, Rheumatoid arthritis, Viral myocarditis Marnetegragene autotemcel 💬 RP-L201 1件: 65 💬
39 KLKB1 💬 1件: Complement and coagulation cascades Conestat alfa 💬 Conestat alfa 1件: 65 💬
40 KLKB1 💬 1件: Complement and coagulation cascades Ecallantide 💬 Ecallantide 1件: 65 💬
41 KLKB1 💬 1件: Complement and coagulation cascades Sebetralstat 💬 Sebetralstat 1件: 65 💬
42 KLKB1 💬 1件: Complement and coagulation cascades Donidalorsen sodium 💬 Donidalorsen 1件: 65 💬
43 KLKB1 💬 1件: Complement and coagulation cascades Lanadelumab 💬 Lanadelumab 1件: 65 💬
44 KLKB1 💬 1件: Complement and coagulation cascades Berotralstat hydrochloride 💬 Berotralstat 1件: 65 💬
45 KLKB1 💬 1件: Complement and coagulation cascades Berotralstat 💬 Berotralstat 1件: 65 💬
46 KLKB1 💬 1件: Complement and coagulation cascades Navenibart 💬 Navenibart 1件: 65 💬
47 MASP2 💬 3件: Complement and coagulation cascades, Staphylococcus aureus infection, Coronavirus disease Narsoplimab 💬 Narsoplimab 3件: 66, 222, 223 💬
48 PLAT 💬 5件: Apelin signaling pathway, Complement and coagulation cascades, Transcriptional misregulation in cancer, Prostate cancer, Fluid shear stress and atherosclerosis Aminocaproic acid 💬 Aminocaproic acid 1件: 70 💬
49 PLG 💬 4件: Neuroactive ligand-receptor interaction, Complement and coagulation cascades, Staphylococcus aureus infection, Influenza A Aminocaproic acid 💬 Aminocaproic acid 1件: 70 💬
50 PLG 💬 4件: Neuroactive ligand-receptor interaction, Complement and coagulation cascades, Staphylococcus aureus infection, Influenza A Tranexamic acid 💬 Tranexamic acid 7件: 46, 65, 70, 215, 227, 274, 299 💬
51 SERPINC1 💬 1件: Complement and coagulation cascades Parnaparin sodium 💬 Parnaparin 1件: 97 💬
52 SERPINC1 💬 1件: Complement and coagulation cascades Danaparoid sodium 💬 Danaparoid 1件: 48 💬
53 SERPINC1 💬 1件: Complement and coagulation cascades Heparin sodium 💬 Heparin 15件: 47, 48, 60, 65, 70, 79, 84, 107, 224, 226, 280, 299, 316, 317, 344 💬
54 SERPINC1 💬 1件: Complement and coagulation cascades Adomiparin 💬 Enoxaparin 6件: 46, 48, 71, 222, 223, 327 💬
55 SERPINC1 💬 1件: Complement and coagulation cascades Tinzaparin sodium 💬 Tinzaparin 1件: 327 💬
56 SERPINC1 💬 1件: Complement and coagulation cascades Enoxaparin sodium 💬 Enoxaparin 6件: 46, 48, 71, 222, 223, 327 💬
57 SERPINC1 💬 1件: Complement and coagulation cascades Heparin calcium 💬 Heparin 15件: 47, 48, 60, 65, 70, 79, 84, 107, 224, 226, 280, 299, 316, 317, 344 💬
58 SERPINC1 💬 1件: Complement and coagulation cascades Dalteparin sodium 💬 Dalteparin 3件: 222, 223, 327 💬
59 VWF 💬 9件: PI3K-Akt signaling pathway, Focal adhesion, ECM-receptor interaction, Integrin signaling, Complement and coagulation cascades, Platelet activation, Neutrophil extracellular trap formation, Human papillomavirus infection, Coronavirus disease Caplacizumab 💬 Caplacizumab 2件: 63, 64 💬