Target Gene/Pathway Pathway / Gene

  

Search results

No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank Disease ID
1 CNR1 💬 [4] Rap1 signaling pathway, Neuroactive ligand-receptor interaction, Thermogenesis, Retrograde endocannabinoid signaling Cannabidiol 💬 Cannabidiol [20] 2, 6, 8, 13, 36, 46, 51, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271 💬
2 CNR2 💬 [1] Neuroactive ligand-receptor interaction Cannabidiol 💬 Cannabidiol [20] 2, 6, 8, 13, 36, 46, 51, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271 💬
3 DRD2 💬 [8] Rap1 signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Alcoholism Risperidone 💬 Risperidone [5] 8, 156, 179, 187, 206 💬
4 DRD2 💬 [8] Rap1 signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Alcoholism Aripiprazole 💬 Aripiprazole [2] 6, 206 💬
5 DRD3 💬 [2] Neuroactive ligand-receptor interaction, Dopaminergic synapse Aripiprazole 💬 Aripiprazole [2] 6, 206 💬
6 GABBR1 💬 [7] cAMP signaling pathway, Neuroactive ligand-receptor interaction, GABAergic synapse, Taste transduction, Estrogen signaling pathway, GnRH secretion, Morphine addiction Baclofen 💬 Baclofen [8] 2, 10, 13, 18, 65, 70, 149, 206 💬
7 GABBR1 💬 [7] cAMP signaling pathway, Neuroactive ligand-receptor interaction, GABAergic synapse, Taste transduction, Estrogen signaling pathway, GnRH secretion, Morphine addiction Arbaclofen 💬 Arbaclofen [2] 13, 206 💬
8 GABRA1 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Flumazenil 💬 Flumazenil [5] 6, 13, 17, 18, 206 💬
9 GABRA1 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Gaboxadol 💬 Gaboxadol [2] 201, 206 💬
10 GABRA1 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Ganaxolone 💬 Ganaxolone [4] 145, 152, 158, 206 💬
11 GABRA2 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Flumazenil 💬 Flumazenil [5] 6, 13, 17, 18, 206 💬
12 GABRA2 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Gaboxadol 💬 Gaboxadol [2] 201, 206 💬
13 GABRA2 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Ganaxolone 💬 Ganaxolone [4] 145, 152, 158, 206 💬
14 GABRA3 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Flumazenil 💬 Flumazenil [5] 6, 13, 17, 18, 206 💬
15 GABRA3 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Gaboxadol 💬 Gaboxadol [2] 201, 206 💬
16 GABRA3 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Ganaxolone 💬 Ganaxolone [4] 145, 152, 158, 206 💬
17 GABRA4 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Flumazenil 💬 Flumazenil [5] 6, 13, 17, 18, 206 💬
18 GABRA4 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Gaboxadol 💬 Gaboxadol [2] 201, 206 💬
19 GABRA4 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Ganaxolone 💬 Ganaxolone [4] 145, 152, 158, 206 💬
20 GABRA5 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Flumazenil 💬 Flumazenil [5] 6, 13, 17, 18, 206 💬
21 GABRA5 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Gaboxadol 💬 Gaboxadol [2] 201, 206 💬
22 GABRA5 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Ganaxolone 💬 Ganaxolone [4] 145, 152, 158, 206 💬
23 GABRA6 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Flumazenil 💬 Flumazenil [5] 6, 13, 17, 18, 206 💬
24 GABRA6 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Gaboxadol 💬 Gaboxadol [2] 201, 206 💬
25 GABRA6 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Ganaxolone 💬 Ganaxolone [4] 145, 152, 158, 206 💬
26 GABRB1 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, Serotonergic synapse, GABAergic synapse, Morphine addiction, Nicotine addiction Flumazenil 💬 Flumazenil [5] 6, 13, 17, 18, 206 💬
27 GABRB1 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, Serotonergic synapse, GABAergic synapse, Morphine addiction, Nicotine addiction Gaboxadol 💬 Gaboxadol [2] 201, 206 💬
28 GABRB1 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, Serotonergic synapse, GABAergic synapse, Morphine addiction, Nicotine addiction Ganaxolone 💬 Ganaxolone [4] 145, 152, 158, 206 💬
29 GABRB2 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, Serotonergic synapse, GABAergic synapse, Morphine addiction, Nicotine addiction Flumazenil 💬 Flumazenil [5] 6, 13, 17, 18, 206 💬
30 GABRB2 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, Serotonergic synapse, GABAergic synapse, Morphine addiction, Nicotine addiction Gaboxadol 💬 Gaboxadol [2] 201, 206 💬
31 GABRB2 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, Serotonergic synapse, GABAergic synapse, Morphine addiction, Nicotine addiction Ganaxolone 💬 Ganaxolone [4] 145, 152, 158, 206 💬
32 GABRB3 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, Serotonergic synapse, GABAergic synapse, Morphine addiction, Nicotine addiction Flumazenil 💬 Flumazenil [5] 6, 13, 17, 18, 206 💬
33 GABRB3 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, Serotonergic synapse, GABAergic synapse, Morphine addiction, Nicotine addiction Gaboxadol 💬 Gaboxadol [2] 201, 206 💬
34 GABRB3 💬 [6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, Serotonergic synapse, GABAergic synapse, Morphine addiction, Nicotine addiction Ganaxolone 💬 Ganaxolone [4] 145, 152, 158, 206 💬
35 GABRD 💬 [5] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Flumazenil 💬 Flumazenil [5] 6, 13, 17, 18, 206 💬
36 GABRD 💬 [5] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Gaboxadol 💬 Gaboxadol [2] 201, 206 💬
37 GABRD 💬 [5] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Ganaxolone 💬 Ganaxolone [4] 145, 152, 158, 206 💬
38 GABRE 💬 [5] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Flumazenil 💬 Flumazenil [5] 6, 13, 17, 18, 206 💬
39 GABRE 💬 [5] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Gaboxadol 💬 Gaboxadol [2] 201, 206 💬
40 GABRE 💬 [5] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Ganaxolone 💬 Ganaxolone [4] 145, 152, 158, 206 💬
41 GABRG1 💬 [5] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Flumazenil 💬 Flumazenil [5] 6, 13, 17, 18, 206 💬
42 GABRG1 💬 [5] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Gaboxadol 💬 Gaboxadol [2] 201, 206 💬
43 GABRG1 💬 [5] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Ganaxolone 💬 Ganaxolone [4] 145, 152, 158, 206 💬
44 GABRG2 💬 [5] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Flumazenil 💬 Flumazenil [5] 6, 13, 17, 18, 206 💬
45 GABRG2 💬 [5] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Gaboxadol 💬 Gaboxadol [2] 201, 206 💬
46 GABRG2 💬 [5] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Ganaxolone 💬 Ganaxolone [4] 145, 152, 158, 206 💬
47 GABRG3 💬 [5] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Flumazenil 💬 Flumazenil [5] 6, 13, 17, 18, 206 💬
48 GABRG3 💬 [5] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Gaboxadol 💬 Gaboxadol [2] 201, 206 💬
49 GABRG3 💬 [5] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Ganaxolone 💬 Ganaxolone [4] 145, 152, 158, 206 💬
50 GABRP 💬 [5] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Flumazenil 💬 Flumazenil [5] 6, 13, 17, 18, 206 💬
51 GABRP 💬 [5] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Gaboxadol 💬 Gaboxadol [2] 201, 206 💬
52 GABRP 💬 [5] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Ganaxolone 💬 Ganaxolone [4] 145, 152, 158, 206 💬
53 GRIA1 💬 [14] cAMP signaling pathway, Neuroactive ligand-receptor interaction, Circadian entrainment, Long-term potentiation, Retrograde endocannabinoid signaling, Glutamatergic synapse, Dopaminergic synapse, Long-term depression, Amyotrophic lateral sclerosis, Huntington disease, Spinocerebellar ataxia, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Nicotine addiction Riluzole 💬 Riluzole [9] 2, 3, 5, 8, 13, 17, 18, 203, 206 💬
54 GRIA2 💬 [15] cAMP signaling pathway, Neuroactive ligand-receptor interaction, Circadian entrainment, Long-term potentiation, Retrograde endocannabinoid signaling, Glutamatergic synapse, Dopaminergic synapse, Long-term depression, Amyotrophic lateral sclerosis, Huntington disease, Spinocerebellar ataxia, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction Riluzole 💬 Riluzole [9] 2, 3, 5, 8, 13, 17, 18, 203, 206 💬
55 GRIA3 💬 [13] cAMP signaling pathway, Neuroactive ligand-receptor interaction, Circadian entrainment, Retrograde endocannabinoid signaling, Glutamatergic synapse, Dopaminergic synapse, Long-term depression, Huntington disease, Spinocerebellar ataxia, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Nicotine addiction, Transcriptional misregulation in cancer Riluzole 💬 Riluzole [9] 2, 3, 5, 8, 13, 17, 18, 203, 206 💬
56 GRIA4 💬 [10] cAMP signaling pathway, Neuroactive ligand-receptor interaction, Circadian entrainment, Retrograde endocannabinoid signaling, Glutamatergic synapse, Dopaminergic synapse, Huntington disease, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Nicotine addiction Riluzole 💬 Riluzole [9] 2, 3, 5, 8, 13, 17, 18, 203, 206 💬
57 GRIK1 💬 [2] Neuroactive ligand-receptor interaction, Glutamatergic synapse Riluzole 💬 Riluzole [9] 2, 3, 5, 8, 13, 17, 18, 203, 206 💬
58 GRIK2 💬 [2] Neuroactive ligand-receptor interaction, Glutamatergic synapse Riluzole 💬 Riluzole [9] 2, 3, 5, 8, 13, 17, 18, 203, 206 💬
59 GRIK3 💬 [2] Neuroactive ligand-receptor interaction, Glutamatergic synapse Riluzole 💬 Riluzole [9] 2, 3, 5, 8, 13, 17, 18, 203, 206 💬
60 GRIK4 💬 [2] Neuroactive ligand-receptor interaction, Glutamatergic synapse Riluzole 💬 Riluzole [9] 2, 3, 5, 8, 13, 17, 18, 203, 206 💬
61 GRIK5 💬 [2] Neuroactive ligand-receptor interaction, Glutamatergic synapse Riluzole 💬 Riluzole [9] 2, 3, 5, 8, 13, 17, 18, 203, 206 💬
62 GRIN1 💬 [18] Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Huntington disease, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism Riluzole 💬 Riluzole [9] 2, 3, 5, 8, 13, 17, 18, 203, 206 💬
63 GRIN1 💬 [18] Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Huntington disease, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism Acamprosate 💬 Acamprosate [2] 6, 206 💬
64 GRIN1 💬 [18] Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Huntington disease, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism Memantine 💬 Memantine [8] 2, 6, 8, 13, 49, 127, 205, 206 💬
65 GRIN2A 💬 [19] Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Dopaminergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism, Systemic lupus erythematosus Riluzole 💬 Riluzole [9] 2, 3, 5, 8, 13, 17, 18, 203, 206 💬
66 GRIN2A 💬 [19] Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Dopaminergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism, Systemic lupus erythematosus Acamprosate 💬 Acamprosate [2] 6, 206 💬
67 GRIN2A 💬 [19] Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Dopaminergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism, Systemic lupus erythematosus Memantine 💬 Memantine [8] 2, 6, 8, 13, 49, 127, 205, 206 💬
68 GRIN2B 💬 [19] Ras signaling pathway, Rap1 signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Dopaminergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Huntington disease, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism, Systemic lupus erythematosus Riluzole 💬 Riluzole [9] 2, 3, 5, 8, 13, 17, 18, 203, 206 💬
69 GRIN2B 💬 [19] Ras signaling pathway, Rap1 signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Dopaminergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Huntington disease, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism, Systemic lupus erythematosus Acamprosate 💬 Acamprosate [2] 6, 206 💬
70 GRIN2B 💬 [19] Ras signaling pathway, Rap1 signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Dopaminergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Huntington disease, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism, Systemic lupus erythematosus Memantine 💬 Memantine [8] 2, 6, 8, 13, 49, 127, 205, 206 💬
71 GRIN2C 💬 [15] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism Riluzole 💬 Riluzole [9] 2, 3, 5, 8, 13, 17, 18, 203, 206 💬
72 GRIN2C 💬 [15] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism Acamprosate 💬 Acamprosate [2] 6, 206 💬
73 GRIN2C 💬 [15] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism Memantine 💬 Memantine [8] 2, 6, 8, 13, 49, 127, 205, 206 💬
74 GRIN2D 💬 [15] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism Riluzole 💬 Riluzole [9] 2, 3, 5, 8, 13, 17, 18, 203, 206 💬
75 GRIN2D 💬 [15] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism Acamprosate 💬 Acamprosate [2] 6, 206 💬
76 GRIN2D 💬 [15] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism Memantine 💬 Memantine [8] 2, 6, 8, 13, 49, 127, 205, 206 💬
77 HMGCR 💬 [4] Terpenoid backbone biosynthesis, Metabolic pathways, AMPK signaling pathway, Bile secretion Lovastatin 💬 Lovastatin [11] 6, 34, 46, 79, 156, 160, 195, 206, 263, 280, 310 💬
78 HTR1A 💬 [4] cAMP signaling pathway, Neuroactive ligand-receptor interaction, Serotonergic synapse, Taste transduction Aripiprazole 💬 Aripiprazole [2] 6, 206 💬
79 HTR2A 💬 [5] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Serotonergic synapse, Inflammatory mediator regulation of TRP channels Risperidone 💬 Risperidone [5] 8, 156, 179, 187, 206 💬
80 HTR2A 💬 [5] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Serotonergic synapse, Inflammatory mediator regulation of TRP channels Aripiprazole 💬 Aripiprazole [2] 6, 206 💬
81 ACHE 💬 [2] Glycerophospholipid metabolism, Cholinergic synapse Donepezil 💬 Donepezil [9] 5, 6, 13, 46, 78, 124, 127, 156, 206 💬
82 OXTR 💬 [4] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Oxytocin signaling pathway Oxytocin 💬 Oxytocin [7] 6, 72, 127, 168, 193, 206, 226 💬
83 PDE4A 💬 [5] Purine metabolism, Metabolic pathways, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Roflumilast 💬 Roflumilast [4] 84, 97, 206, 299 💬
84 PDE4B 💬 [5] Purine metabolism, Metabolic pathways, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Roflumilast 💬 Roflumilast [4] 84, 97, 206, 299 💬
85 PDE4C 💬 [5] Purine metabolism, Metabolic pathways, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Roflumilast 💬 Roflumilast [4] 84, 97, 206, 299 💬
86 PDE4D 💬 [5] Purine metabolism, Metabolic pathways, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Roflumilast 💬 Roflumilast [4] 84, 97, 206, 299 💬
87 PDE4D 💬 [5] Purine metabolism, Metabolic pathways, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Zatolmilast 💬 Zatolmilast [1] 206 💬
88 PRKAA1 💬 [20] FoxO signaling pathway, Autophagy - animal, mTOR signaling pathway, PI3K-Akt signaling pathway, AMPK signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Apelin signaling pathway, Tight junction, Circadian rhythm, Thermogenesis, Insulin signaling pathway, Adipocytokine signaling pathway, Oxytocin signaling pathway, Glucagon signaling pathway, Insulin resistance, Non-alcoholic fatty liver disease, Alcoholic liver disease, Hypertrophic cardiomyopathy, Fluid shear stress and atherosclerosis Metformin 💬 Metformin [25] 2, 6, 8, 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
89 PRKAA2 💬 [20] FoxO signaling pathway, Autophagy - animal, mTOR signaling pathway, PI3K-Akt signaling pathway, AMPK signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Apelin signaling pathway, Tight junction, Circadian rhythm, Thermogenesis, Insulin signaling pathway, Adipocytokine signaling pathway, Oxytocin signaling pathway, Glucagon signaling pathway, Insulin resistance, Non-alcoholic fatty liver disease, Alcoholic liver disease, Hypertrophic cardiomyopathy, Fluid shear stress and atherosclerosis Metformin 💬 Metformin [25] 2, 6, 8, 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
90 GABRQ 💬 [5] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Flumazenil 💬 Flumazenil [5] 6, 13, 17, 18, 206 💬
91 GABRQ 💬 [5] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Gaboxadol 💬 Gaboxadol [2] 201, 206 💬
92 GABRQ 💬 [5] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Ganaxolone 💬 Ganaxolone [4] 145, 152, 158, 206 💬
93 PTGS1 💬 [5] Arachidonic acid metabolism, Metabolic pathways, Platelet activation, Serotonergic synapse, Regulation of lipolysis in adipocytes Sulindac 💬 Sulindac [1] 206 💬
94 PTGS2 💬 [22] Arachidonic acid metabolism, Metabolic pathways, NF-kappa B signaling pathway, VEGF signaling pathway, C-type lectin receptor signaling pathway, IL-17 signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Ovarian steroidogenesis, Oxytocin signaling pathway, Regulation of lipolysis in adipocytes, Alzheimer disease, Pathways of neurodegeneration - multiple diseases, Leishmaniasis, Human cytomegalovirus infection, Human papillomavirus infection, Kaposi sarcoma-associated herpesvirus infection, Pathways in cancer, Chemical carcinogenesis - DNA adducts, MicroRNAs in cancer, Small cell lung cancer Sulindac 💬 Sulindac [1] 206 💬
95 SLC6A2 💬 [1] Synaptic vesicle cycle Methylphenidate 💬 Methylphenidate [7] 6, 13, 34, 84, 113, 179, 206 💬
96 SLC6A3 💬 [7] Synaptic vesicle cycle, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Alcoholism Methylphenidate 💬 Methylphenidate [7] 6, 13, 34, 84, 113, 179, 206 💬
97 SLC6A4 💬 [2] Synaptic vesicle cycle, Serotonergic synapse Fluoxetine 💬 Fluoxetine [6] 13, 17, 78, 86, 179, 206 💬
98 SLC6A4 💬 [2] Synaptic vesicle cycle, Serotonergic synapse Sertraline 💬 Sertraline [2] 6, 206 💬
99 GABBR2 💬 [7] cAMP signaling pathway, Neuroactive ligand-receptor interaction, GABAergic synapse, Taste transduction, Estrogen signaling pathway, GnRH secretion, Morphine addiction Baclofen 💬 Baclofen [8] 2, 10, 13, 18, 65, 70, 149, 206 💬
100 GABBR2 💬 [7] cAMP signaling pathway, Neuroactive ligand-receptor interaction, GABAergic synapse, Taste transduction, Estrogen signaling pathway, GnRH secretion, Morphine addiction Arbaclofen 💬 Arbaclofen [2] 13, 206 💬