Target Gene/Pathway Pathway / Gene

  

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No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank 指定難病告示番号
1 FDPS 💬 3件: Terpenoid backbone biosynthesis, Influenza A, Human T-cell leukemia virus 1 infection Zoledronic acid hemipentahydrate 💬 Zoledronic acid 16件: 5, 6, 13, 17, 46, 75, 77, 93, 95, 96, 97, 270, 274, 282, 299, 333 💬
2 FDPS 💬 3件: Terpenoid backbone biosynthesis, Influenza A, Human T-cell leukemia virus 1 infection Zoledronate disodium 💬 Zoledronic acid 16件: 5, 6, 13, 17, 46, 75, 77, 93, 95, 96, 97, 270, 274, 282, 299, 333 💬
3 FDPS 💬 3件: Terpenoid backbone biosynthesis, Influenza A, Human T-cell leukemia virus 1 infection Zoledronate trisodium 💬 Zoledronic acid 16件: 5, 6, 13, 17, 46, 75, 77, 93, 95, 96, 97, 270, 274, 282, 299, 333 💬
4 FDPS 💬 3件: Terpenoid backbone biosynthesis, Influenza A, Human T-cell leukemia virus 1 infection Alendronic acid 💬 Alendronic acid 5件: 19, 46, 223, 274, 299 💬
5 FDPS 💬 3件: Terpenoid backbone biosynthesis, Influenza A, Human T-cell leukemia virus 1 infection Risedronate sodium 💬 Risedronic acid 7件: 46, 50, 93, 95, 107, 113, 274 💬
6 FDPS 💬 3件: Terpenoid backbone biosynthesis, Influenza A, Human T-cell leukemia virus 1 infection Risedronic acid 💬 Risedronic acid 7件: 46, 50, 93, 95, 107, 113, 274 💬
7 FDPS 💬 3件: Terpenoid backbone biosynthesis, Influenza A, Human T-cell leukemia virus 1 infection Alendronate sodium 💬 Alendronic acid 5件: 19, 46, 223, 274, 299 💬
8 FDPS 💬 3件: Terpenoid backbone biosynthesis, Influenza A, Human T-cell leukemia virus 1 infection Pamidronate disodium 💬 Pamidronic acid 1件: 274 💬
9 FDPS 💬 3件: Terpenoid backbone biosynthesis, Influenza A, Human T-cell leukemia virus 1 infection Pamidronic acid 💬 Pamidronic acid 1件: 274 💬
10 FDPS 💬 3件: Terpenoid backbone biosynthesis, Influenza A, Human T-cell leukemia virus 1 infection Zoledronic acid 💬 Zoledronic acid 16件: 5, 6, 13, 17, 46, 75, 77, 93, 95, 96, 97, 270, 274, 282, 299, 333 💬
11 FDPS 💬 3件: Terpenoid backbone biosynthesis, Influenza A, Human T-cell leukemia virus 1 infection Zoledronic acid 💬 Zoledronic acid 16件: 5, 6, 13, 17, 46, 75, 77, 93, 95, 96, 97, 270, 274, 282, 299, 333 💬
12 FDPS 💬 3件: Terpenoid backbone biosynthesis, Influenza A, Human T-cell leukemia virus 1 infection Risedronate sodium monohydrate 💬 Risedronic acid 7件: 46, 50, 93, 95, 107, 113, 274 💬
13 MS4A1 💬 1件: Hematopoietic cell lineage Rituximab 💬 Rituximab 54件: 11, 13, 14, 19, 26, 34, 35, 36, 40, 41, 42, 43, 44, 45, 46, 48, 49, 50, 51, 52, 53, 55, 56, 60, 61, 62, 63, 64, 65, 66, 83, 84, 85, 86, 88, 93, 94, 96, 97, 162, 172, 222, 223, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331 💬
14 PLG 💬 4件: Neuroactive ligand-receptor interaction, Complement and coagulation cascades, Staphylococcus aureus infection, Influenza A Tranexamic acid 💬 Tranexamic acid 7件: 46, 65, 70, 215, 227, 274, 299 💬
15 PTH1R 💬 4件: Neuroactive ligand-receptor interaction, Hormone signaling, Parathyroid hormone synthesis, secretion and action, Endocrine and other factor-regulated calcium reabsorption Teriparatide acetate 💬 Teriparatide 7件: 46, 68, 70, 71, 172, 235, 274 💬
16 PTH1R 💬 4件: Neuroactive ligand-receptor interaction, Hormone signaling, Parathyroid hormone synthesis, secretion and action, Endocrine and other factor-regulated calcium reabsorption Teriparatide acetate 💬 Teriparatide 7件: 46, 68, 70, 71, 172, 235, 274 💬
17 PTH1R 💬 4件: Neuroactive ligand-receptor interaction, Hormone signaling, Parathyroid hormone synthesis, secretion and action, Endocrine and other factor-regulated calcium reabsorption Teriparatide 💬 Teriparatide 7件: 46, 68, 70, 71, 172, 235, 274 💬
18 SOST 💬 2件: Wnt signaling pathway, Parathyroid hormone synthesis, secretion and action Setrusumab 💬 Setrusumab 1件: 274 💬
19 SOST 💬 2件: Wnt signaling pathway, Parathyroid hormone synthesis, secretion and action Romosozumab 💬 Romosozumab 2件: 46, 274 💬
20 TGFB1 💬 36件: MAPK signaling pathway, Cytokine-cytokine receptor interaction, FoxO signaling pathway, Cell cycle, Efferocytosis, Cellular senescence, TGF-beta signaling pathway, Osteoclast differentiation, Hippo signaling pathway, Integrin signaling, Th17 cell differentiation, Intestinal immune network for IgA production, Relaxin signaling pathway, Non-alcoholic fatty liver disease, AGE-RAGE signaling pathway in diabetic complications, Leishmaniasis, Chagas disease, Malaria, Toxoplasmosis, Amoebiasis, Tuberculosis, Hepatitis B, Human T-cell leukemia virus 1 infection, Pathways in cancer, Proteoglycans in cancer, Colorectal cancer, Renal cell carcinoma, Pancreatic cancer, Chronic myeloid leukemia, Hepatocellular carcinoma, Gastric cancer, Inflammatory bowel disease, Rheumatoid arthritis, Hypertrophic cardiomyopathy, Dilated cardiomyopathy, Diabetic cardiomyopathy Fresolimumab 💬 Fresolimumab 3件: 51, 222, 274 💬
21 TGFB2 💬 31件: MAPK signaling pathway, Cytokine-cytokine receptor interaction, FoxO signaling pathway, Cell cycle, Cellular senescence, TGF-beta signaling pathway, Osteoclast differentiation, Hippo signaling pathway, AGE-RAGE signaling pathway in diabetic complications, Leishmaniasis, Chagas disease, Malaria, Toxoplasmosis, Amoebiasis, Tuberculosis, Hepatitis B, Human T-cell leukemia virus 1 infection, Pathways in cancer, Proteoglycans in cancer, MicroRNAs in cancer, Colorectal cancer, Renal cell carcinoma, Pancreatic cancer, Chronic myeloid leukemia, Hepatocellular carcinoma, Gastric cancer, Inflammatory bowel disease, Rheumatoid arthritis, Hypertrophic cardiomyopathy, Dilated cardiomyopathy, Diabetic cardiomyopathy Fresolimumab 💬 Fresolimumab 3件: 51, 222, 274 💬
22 TGFB3 💬 28件: MAPK signaling pathway, Cytokine-cytokine receptor interaction, FoxO signaling pathway, Cell cycle, Cellular senescence, TGF-beta signaling pathway, Hippo signaling pathway, AGE-RAGE signaling pathway in diabetic complications, Leishmaniasis, Chagas disease, Malaria, Toxoplasmosis, Amoebiasis, Tuberculosis, Hepatitis B, Human T-cell leukemia virus 1 infection, Pathways in cancer, Colorectal cancer, Renal cell carcinoma, Pancreatic cancer, Chronic myeloid leukemia, Hepatocellular carcinoma, Gastric cancer, Inflammatory bowel disease, Rheumatoid arthritis, Hypertrophic cardiomyopathy, Dilated cardiomyopathy, Diabetic cardiomyopathy Fresolimumab 💬 Fresolimumab 3件: 51, 222, 274 💬
23 TNFSF11 💬 8件: Cytokine-cytokine receptor interaction, NF-kappa B signaling pathway, Osteoclast differentiation, Prolactin signaling pathway, Parathyroid hormone synthesis, secretion and action, Chemical carcinogenesis - receptor activation, Breast cancer, Rheumatoid arthritis Denosumab 💬 Denosumab 11件: 46, 50, 70, 75, 77, 93, 95, 96, 223, 274, 299 💬