Target Gene/Pathway Pathway / Gene

  

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No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank 指定難病告示番号
1 CHRNA4 💬 5件: Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cholinergic synapse, Nicotine addiction, Chemical carcinogenesis - receptor activation Varenicline 💬 Varenicline 3件: 6, 18, 53 💬
2 CHRNA4 💬 5件: Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cholinergic synapse, Nicotine addiction, Chemical carcinogenesis - receptor activation Varenicline tartrate 💬 Varenicline 3件: 6, 18, 53 💬
3 CHRNB2 💬 5件: Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cholinergic synapse, Nicotine addiction, Chemical carcinogenesis - receptor activation Varenicline 💬 Varenicline 3件: 6, 18, 53 💬
4 CHRNB2 💬 5件: Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cholinergic synapse, Nicotine addiction, Chemical carcinogenesis - receptor activation Varenicline tartrate 💬 Varenicline 3件: 6, 18, 53 💬
5 CSF3R 💬 5件: Cytokine-cytokine receptor interaction, PI3K-Akt signaling pathway, JAK-STAT signaling pathway, Hematopoietic cell lineage, Pathways in cancer Lenograstim 💬 Lenograstim 8件: 2, 13, 16, 18, 19, 57, 65, 97 💬
6 EPOR 💬 7件: Cytokine-cytokine receptor interaction, Hormone signaling, Efferocytosis, PI3K-Akt signaling pathway, JAK-STAT signaling pathway, Hematopoietic cell lineage, Pathways in cancer Epoetin theta 💬 Erythropoietin 11件: 2, 6, 13, 18, 22, 46, 47, 61, 70, 95, 96 💬
7 EPOR 💬 7件: Cytokine-cytokine receptor interaction, Hormone signaling, Efferocytosis, PI3K-Akt signaling pathway, JAK-STAT signaling pathway, Hematopoietic cell lineage, Pathways in cancer Epoetin alfa 💬 Erythropoietin 11件: 2, 6, 13, 18, 22, 46, 47, 61, 70, 95, 96 💬
8 EPOR 💬 7件: Cytokine-cytokine receptor interaction, Hormone signaling, Efferocytosis, PI3K-Akt signaling pathway, JAK-STAT signaling pathway, Hematopoietic cell lineage, Pathways in cancer Epoetin beta 💬 Epoetin beta 2件: 13, 18 💬
9 EPOR 💬 7件: Cytokine-cytokine receptor interaction, Hormone signaling, Efferocytosis, PI3K-Akt signaling pathway, JAK-STAT signaling pathway, Hematopoietic cell lineage, Pathways in cancer Epoetin zeta 💬 Erythropoietin 11件: 2, 6, 13, 18, 22, 46, 47, 61, 70, 95, 96 💬
10 EPOR 💬 7件: Cytokine-cytokine receptor interaction, Hormone signaling, Efferocytosis, PI3K-Akt signaling pathway, JAK-STAT signaling pathway, Hematopoietic cell lineage, Pathways in cancer Epoetin epsilon 💬 Erythropoietin 11件: 2, 6, 13, 18, 22, 46, 47, 61, 70, 95, 96 💬
11 GABBR 💬 8件: cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, GABAergic synapse, Taste transduction, Estrogen signaling pathway, GnRH secretion, Morphine addiction Baclofen 💬 Baclofen 8件: 2, 10, 13, 18, 65, 70, 149, 206 💬
12 GABBR 💬 8件: cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, GABAergic synapse, Taste transduction, Estrogen signaling pathway, GnRH secretion, Morphine addiction Baclofen 💬 Baclofen 8件: 2, 10, 13, 18, 65, 70, 149, 206 💬
13 GABRA 💬 7件: Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Flumazenil 💬 Flumazenil 5件: 6, 13, 17, 18, 206 💬
14 GABRA 💬 7件: Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Flumazenil 💬 Flumazenil 5件: 6, 13, 17, 18, 206 💬
15 GABRA 💬 7件: Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Flumazenil 💬 Flumazenil 5件: 6, 13, 17, 18, 206 💬
16 GABRA 💬 7件: Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Flumazenil 💬 Flumazenil 5件: 6, 13, 17, 18, 206 💬
17 GABRA 💬 7件: Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Flumazenil 💬 Flumazenil 5件: 6, 13, 17, 18, 206 💬
18 GABRA 💬 7件: Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Flumazenil 💬 Flumazenil 5件: 6, 13, 17, 18, 206 💬
19 GABRB 💬 7件: Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Retrograde endocannabinoid signaling, Serotonergic synapse, GABAergic synapse, Morphine addiction, Nicotine addiction Flumazenil 💬 Flumazenil 5件: 6, 13, 17, 18, 206 💬
20 GABRB 💬 7件: Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Retrograde endocannabinoid signaling, Serotonergic synapse, GABAergic synapse, Morphine addiction, Nicotine addiction Flumazenil 💬 Flumazenil 5件: 6, 13, 17, 18, 206 💬
21 GABRB 💬 7件: Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Retrograde endocannabinoid signaling, Serotonergic synapse, GABAergic synapse, Morphine addiction, Nicotine addiction Flumazenil 💬 Flumazenil 5件: 6, 13, 17, 18, 206 💬
22 GABRD 💬 6件: Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Flumazenil 💬 Flumazenil 5件: 6, 13, 17, 18, 206 💬
23 GABRE 💬 6件: Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Flumazenil 💬 Flumazenil 5件: 6, 13, 17, 18, 206 💬
24 GABRG 💬 6件: Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Flumazenil 💬 Flumazenil 5件: 6, 13, 17, 18, 206 💬
25 GABRG 💬 6件: Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Flumazenil 💬 Flumazenil 5件: 6, 13, 17, 18, 206 💬
26 GABRG 💬 6件: Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Flumazenil 💬 Flumazenil 5件: 6, 13, 17, 18, 206 💬
27 GABRP 💬 6件: Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Flumazenil 💬 Flumazenil 5件: 6, 13, 17, 18, 206 💬
28 GABRQ 💬 6件: Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Flumazenil 💬 Flumazenil 5件: 6, 13, 17, 18, 206 💬
29 HMGCR 💬 3件: Terpenoid backbone biosynthesis, AMPK signaling pathway, Bile secretion Rosuvastatin calcium 💬 Rosuvastatin 13件: 6, 18, 46, 49, 51, 56, 65, 79, 94, 96, 97, 271, 299 💬
30 HMGCR 💬 3件: Terpenoid backbone biosynthesis, AMPK signaling pathway, Bile secretion Rosuvastatin 💬 Rosuvastatin 13件: 6, 18, 46, 49, 51, 56, 65, 79, 94, 96, 97, 271, 299 💬
31 IFNGR1 💬 18件: Cytokine-cytokine receptor interaction, HIF-1 signaling pathway, Necroptosis, Osteoclast differentiation, JAK-STAT signaling pathway, Natural killer cell mediated cytotoxicity, Th1 and Th2 cell differentiation, Th17 cell differentiation, Leishmaniasis, Chagas disease, Toxoplasmosis, Tuberculosis, Influenza A, Kaposi sarcoma-associated herpesvirus infection, Herpes simplex virus 1 infection, Pathways in cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer, Inflammatory bowel disease Interferon gamma-1b 💬 Interferon gamma-1b 7件: 18, 65, 85, 228, 299, 301, 326 💬
32 IFNGR2 💬 17件: Cytokine-cytokine receptor interaction, HIF-1 signaling pathway, Necroptosis, Osteoclast differentiation, JAK-STAT signaling pathway, Natural killer cell mediated cytotoxicity, Th1 and Th2 cell differentiation, Th17 cell differentiation, Leishmaniasis, Chagas disease, Toxoplasmosis, Tuberculosis, Influenza A, Herpes simplex virus 1 infection, Pathways in cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer, Inflammatory bowel disease Interferon gamma-1b 💬 Interferon gamma-1b 7件: 18, 65, 85, 228, 299, 301, 326 💬
33 NFE2L2 💬 7件: Protein processing in endoplasmic reticulum, Parkinson disease, Pathways in cancer, Chemical carcinogenesis - reactive oxygen species, Hepatocellular carcinoma, Lipid and atherosclerosis, Fluid shear stress and atherosclerosis Omaveloxolone 💬 Omaveloxolone 1件: 18 💬
34 NR3C1 💬 1件: Neuroactive ligand-receptor interaction Prednisolone 💬 Prednisolone 41件: 3, 11, 13, 14, 18, 25, 26, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 54, 56, 60, 61, 63, 64, 66, 81, 84, 85, 95, 96, 97, 113, 145, 162, 222, 251, 269, 271, 296, 299, 300 💬
35 NR3C1 💬 1件: Neuroactive ligand-receptor interaction Methylprednisolone acetate 💬 Methylprednisolone 48件: 2, 6, 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 95, 96, 97, 127, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296, 300 💬
36 NR3C1 💬 1件: Neuroactive ligand-receptor interaction Methylprednisolone 💬 Methylprednisolone 48件: 2, 6, 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 95, 96, 97, 127, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296, 300 💬
37 NR3C1 💬 1件: Neuroactive ligand-receptor interaction Prednisone 💬 Prednisone 54件: 2, 11, 13, 14, 18, 19, 26, 28, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 60, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 90, 93, 95, 96, 97, 113, 145, 162, 164, 205, 222, 224, 228, 251, 269, 283, 285, 288, 299, 300, 303, 307, 331 💬
38 SLC6A2 💬 2件: Neuroactive ligand signaling, Synaptic vesicle cycle Bupropion hydrochloride 💬 Bupropion 6件: 8, 18, 21, 96, 97, 171 💬
39 SLC6A2 💬 2件: Neuroactive ligand signaling, Synaptic vesicle cycle Bupropion hydrobromide 💬 Bupropion 6件: 8, 18, 21, 96, 97, 171 💬
40 SLC6A2 💬 2件: Neuroactive ligand signaling, Synaptic vesicle cycle Bupropion 💬 Bupropion 6件: 8, 18, 21, 96, 97, 171 💬
41 SLC6A3 💬 8件: Neuroactive ligand signaling, Synaptic vesicle cycle, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Alcoholism Bupropion hydrochloride 💬 Bupropion 6件: 8, 18, 21, 96, 97, 171 💬
42 SLC6A3 💬 8件: Neuroactive ligand signaling, Synaptic vesicle cycle, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Alcoholism Bupropion 💬 Bupropion 6件: 8, 18, 21, 96, 97, 171 💬
43 SLC6A3 💬 8件: Neuroactive ligand signaling, Synaptic vesicle cycle, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Alcoholism Bupropion hydrobromide 💬 Bupropion 6件: 8, 18, 21, 96, 97, 171 💬
44 VDR 💬 5件: Parathyroid hormone synthesis, secretion and action, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Tuberculosis, Chemical carcinogenesis - receptor activation Calcitriol 💬 Calcitriol 8件: 18, 37, 46, 49, 66, 96, 235, 326 💬