Target Gene/Pathway Pathway / Gene

  

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No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank 指定難病告示番号
1 ATP1A1 💬 19件: cGMP-PKG signaling pathway, cAMP signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Cytoskeleton in muscle cells, Insulin secretion, Thyroid hormone synthesis, Thyroid hormone signaling pathway, Aldosterone synthesis and secretion, Aldosterone-regulated sodium reabsorption, Endocrine and other factor-regulated calcium reabsorption, Proximal tubule bicarbonate reclamation, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Carbohydrate digestion and absorption, Protein digestion and absorption, Bile secretion, Mineral absorption Digoxin 💬 Digoxin 7件: 2, 8, 46, 57, 65, 67, 210 💬
2 ATP1A1 💬 19件: cGMP-PKG signaling pathway, cAMP signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Cytoskeleton in muscle cells, Insulin secretion, Thyroid hormone synthesis, Thyroid hormone signaling pathway, Aldosterone synthesis and secretion, Aldosterone-regulated sodium reabsorption, Endocrine and other factor-regulated calcium reabsorption, Proximal tubule bicarbonate reclamation, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Carbohydrate digestion and absorption, Protein digestion and absorption, Bile secretion, Mineral absorption Digitoxin 💬 Digitoxin 1件: 299 💬
3 ATP1A2 💬 19件: cGMP-PKG signaling pathway, cAMP signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Cytoskeleton in muscle cells, Insulin secretion, Thyroid hormone synthesis, Thyroid hormone signaling pathway, Aldosterone synthesis and secretion, Aldosterone-regulated sodium reabsorption, Endocrine and other factor-regulated calcium reabsorption, Proximal tubule bicarbonate reclamation, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Carbohydrate digestion and absorption, Protein digestion and absorption, Bile secretion, Mineral absorption Digitoxin 💬 Digitoxin 1件: 299 💬
4 ATP1A2 💬 19件: cGMP-PKG signaling pathway, cAMP signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Cytoskeleton in muscle cells, Insulin secretion, Thyroid hormone synthesis, Thyroid hormone signaling pathway, Aldosterone synthesis and secretion, Aldosterone-regulated sodium reabsorption, Endocrine and other factor-regulated calcium reabsorption, Proximal tubule bicarbonate reclamation, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Carbohydrate digestion and absorption, Protein digestion and absorption, Bile secretion, Mineral absorption Digoxin 💬 Digoxin 7件: 2, 8, 46, 57, 65, 67, 210 💬
5 ATP1A3 💬 19件: cGMP-PKG signaling pathway, cAMP signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Cytoskeleton in muscle cells, Insulin secretion, Thyroid hormone synthesis, Thyroid hormone signaling pathway, Aldosterone synthesis and secretion, Aldosterone-regulated sodium reabsorption, Endocrine and other factor-regulated calcium reabsorption, Proximal tubule bicarbonate reclamation, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Carbohydrate digestion and absorption, Protein digestion and absorption, Bile secretion, Mineral absorption Digitoxin 💬 Digitoxin 1件: 299 💬
6 ATP1A3 💬 19件: cGMP-PKG signaling pathway, cAMP signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Cytoskeleton in muscle cells, Insulin secretion, Thyroid hormone synthesis, Thyroid hormone signaling pathway, Aldosterone synthesis and secretion, Aldosterone-regulated sodium reabsorption, Endocrine and other factor-regulated calcium reabsorption, Proximal tubule bicarbonate reclamation, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Carbohydrate digestion and absorption, Protein digestion and absorption, Bile secretion, Mineral absorption Digoxin 💬 Digoxin 7件: 2, 8, 46, 57, 65, 67, 210 💬
7 ATP1A4 💬 19件: cGMP-PKG signaling pathway, cAMP signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Cytoskeleton in muscle cells, Insulin secretion, Thyroid hormone synthesis, Thyroid hormone signaling pathway, Aldosterone synthesis and secretion, Aldosterone-regulated sodium reabsorption, Endocrine and other factor-regulated calcium reabsorption, Proximal tubule bicarbonate reclamation, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Carbohydrate digestion and absorption, Protein digestion and absorption, Bile secretion, Mineral absorption Digitoxin 💬 Digitoxin 1件: 299 💬
8 ATP1A4 💬 19件: cGMP-PKG signaling pathway, cAMP signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Cytoskeleton in muscle cells, Insulin secretion, Thyroid hormone synthesis, Thyroid hormone signaling pathway, Aldosterone synthesis and secretion, Aldosterone-regulated sodium reabsorption, Endocrine and other factor-regulated calcium reabsorption, Proximal tubule bicarbonate reclamation, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Carbohydrate digestion and absorption, Protein digestion and absorption, Bile secretion, Mineral absorption Digoxin 💬 Digoxin 7件: 2, 8, 46, 57, 65, 67, 210 💬
9 ATP4A 💬 3件: Oxidative phosphorylation, Collecting duct acid secretion, Gastric acid secretion Esomeprazole 💬 Esomeprazole 10件: 6, 13, 46, 86, 98, 107, 113, 234, 298, 299 💬
10 ATP4A 💬 3件: Oxidative phosphorylation, Collecting duct acid secretion, Gastric acid secretion Pantoprazole 💬 Pantoprazole 2件: 13, 65 💬
11 ATP4A 💬 3件: Oxidative phosphorylation, Collecting duct acid secretion, Gastric acid secretion Dexlansoprazole sesquihydrate 💬 Dexlansoprazole 1件: 98 💬
12 ATP4A 💬 3件: Oxidative phosphorylation, Collecting duct acid secretion, Gastric acid secretion Omeprazole magnesium 💬 Omeprazole 18件: 6, 8, 13, 21, 46, 51, 67, 85, 90, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬
13 ATP4A 💬 3件: Oxidative phosphorylation, Collecting duct acid secretion, Gastric acid secretion Dexlansoprazole 💬 Dexlansoprazole 1件: 98 💬
14 ATP4A 💬 3件: Oxidative phosphorylation, Collecting duct acid secretion, Gastric acid secretion Vonoprazan 💬 Vonoprazan 3件: 63, 97, 98 💬
15 ATP4A 💬 3件: Oxidative phosphorylation, Collecting duct acid secretion, Gastric acid secretion Pantoprazole sodium 💬 Pantoprazole 2件: 13, 65 💬
16 ATP4A 💬 3件: Oxidative phosphorylation, Collecting duct acid secretion, Gastric acid secretion Omeprazole 💬 Omeprazole 18件: 6, 8, 13, 21, 46, 51, 67, 85, 90, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬
17 ATP4A 💬 3件: Oxidative phosphorylation, Collecting duct acid secretion, Gastric acid secretion Rabeprazole 💬 Rabeprazole 3件: 2, 6, 51 💬
18 ATP4A 💬 3件: Oxidative phosphorylation, Collecting duct acid secretion, Gastric acid secretion Lansoprazole 💬 Lansoprazole 8件: 63, 71, 85, 98, 166, 222, 223, 299 💬
19 ATP4A 💬 3件: Oxidative phosphorylation, Collecting duct acid secretion, Gastric acid secretion Esomeprazole magnesium dihydrate 💬 Esomeprazole 10件: 6, 13, 46, 86, 98, 107, 113, 234, 298, 299 💬
20 ATP4A 💬 3件: Oxidative phosphorylation, Collecting duct acid secretion, Gastric acid secretion Omeprazole sodium 💬 Omeprazole 18件: 6, 8, 13, 21, 46, 51, 67, 85, 90, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬
21 ATP4A 💬 3件: Oxidative phosphorylation, Collecting duct acid secretion, Gastric acid secretion Esomeprazole sodium 💬 Esomeprazole 10件: 6, 13, 46, 86, 98, 107, 113, 234, 298, 299 💬
22 ATP4A 💬 3件: Oxidative phosphorylation, Collecting duct acid secretion, Gastric acid secretion Esomeprazole magnesium 💬 Esomeprazole 10件: 6, 13, 46, 86, 98, 107, 113, 234, 298, 299 💬
23 ATP4A 💬 3件: Oxidative phosphorylation, Collecting duct acid secretion, Gastric acid secretion Esomeprazole strontium 💬 Esomeprazole 10件: 6, 13, 46, 86, 98, 107, 113, 234, 298, 299 💬
24 ATP4A 💬 3件: Oxidative phosphorylation, Collecting duct acid secretion, Gastric acid secretion Rabeprazole sodium 💬 Rabeprazole 3件: 2, 6, 51 💬
25 ATP4B 💬 3件: Oxidative phosphorylation, Collecting duct acid secretion, Gastric acid secretion Lansoprazole 💬 Lansoprazole 8件: 63, 71, 85, 98, 166, 222, 223, 299 💬
26 ATP4B 💬 3件: Oxidative phosphorylation, Collecting duct acid secretion, Gastric acid secretion Dexlansoprazole 💬 Dexlansoprazole 1件: 98 💬
27 ATP4B 💬 3件: Oxidative phosphorylation, Collecting duct acid secretion, Gastric acid secretion Omeprazole 💬 Omeprazole 18件: 6, 8, 13, 21, 46, 51, 67, 85, 90, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬
28 ATP4B 💬 3件: Oxidative phosphorylation, Collecting duct acid secretion, Gastric acid secretion Rabeprazole 💬 Rabeprazole 3件: 2, 6, 51 💬
29 ATP4B 💬 3件: Oxidative phosphorylation, Collecting duct acid secretion, Gastric acid secretion Pantoprazole sodium 💬 Pantoprazole 2件: 13, 65 💬
30 ATP4B 💬 3件: Oxidative phosphorylation, Collecting duct acid secretion, Gastric acid secretion Esomeprazole sodium 💬 Esomeprazole 10件: 6, 13, 46, 86, 98, 107, 113, 234, 298, 299 💬
31 ATP4B 💬 3件: Oxidative phosphorylation, Collecting duct acid secretion, Gastric acid secretion Omeprazole magnesium 💬 Omeprazole 18件: 6, 8, 13, 21, 46, 51, 67, 85, 90, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬
32 ATP4B 💬 3件: Oxidative phosphorylation, Collecting duct acid secretion, Gastric acid secretion Omeprazole sodium 💬 Omeprazole 18件: 6, 8, 13, 21, 46, 51, 67, 85, 90, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬
33 ATP4B 💬 3件: Oxidative phosphorylation, Collecting duct acid secretion, Gastric acid secretion Rabeprazole sodium 💬 Rabeprazole 3件: 2, 6, 51 💬
34 ATP4B 💬 3件: Oxidative phosphorylation, Collecting duct acid secretion, Gastric acid secretion Esomeprazole magnesium 💬 Esomeprazole 10件: 6, 13, 46, 86, 98, 107, 113, 234, 298, 299 💬
35 ATP4B 💬 3件: Oxidative phosphorylation, Collecting duct acid secretion, Gastric acid secretion Dexlansoprazole sesquihydrate 💬 Dexlansoprazole 1件: 98 💬
36 ATP4B 💬 3件: Oxidative phosphorylation, Collecting duct acid secretion, Gastric acid secretion Vonoprazan 💬 Vonoprazan 3件: 63, 97, 98 💬
37 ATP4B 💬 3件: Oxidative phosphorylation, Collecting duct acid secretion, Gastric acid secretion Esomeprazole strontium 💬 Esomeprazole 10件: 6, 13, 46, 86, 98, 107, 113, 234, 298, 299 💬
38 ATP4B 💬 3件: Oxidative phosphorylation, Collecting duct acid secretion, Gastric acid secretion Esomeprazole 💬 Esomeprazole 10件: 6, 13, 46, 86, 98, 107, 113, 234, 298, 299 💬
39 ATP4B 💬 3件: Oxidative phosphorylation, Collecting duct acid secretion, Gastric acid secretion Pantoprazole 💬 Pantoprazole 2件: 13, 65 💬
40 ATP4B 💬 3件: Oxidative phosphorylation, Collecting duct acid secretion, Gastric acid secretion Esomeprazole magnesium dihydrate 💬 Esomeprazole 10件: 6, 13, 46, 86, 98, 107, 113, 234, 298, 299 💬
41 CA2 💬 6件: Nitrogen metabolism, Proximal tubule bicarbonate reclamation, Collecting duct acid secretion, Gastric acid secretion, Pancreatic secretion, Bile secretion Topiramate 💬 Topiramate 6件: 6, 97, 140, 144, 156, 193 💬
42 CA2 💬 6件: Nitrogen metabolism, Proximal tubule bicarbonate reclamation, Collecting duct acid secretion, Gastric acid secretion, Pancreatic secretion, Bile secretion Acetazolamide 💬 Acetazolamide 8件: 13, 67, 90, 115, 155, 222, 225, 230 💬
43 CA2 💬 6件: Nitrogen metabolism, Proximal tubule bicarbonate reclamation, Collecting duct acid secretion, Gastric acid secretion, Pancreatic secretion, Bile secretion Dorzolamide hydrochloride 💬 Dorzolamide 1件: 90 💬
44 CA2 💬 6件: Nitrogen metabolism, Proximal tubule bicarbonate reclamation, Collecting duct acid secretion, Gastric acid secretion, Pancreatic secretion, Bile secretion Dorzolamide 💬 Dorzolamide 1件: 90 💬
45 CA2 💬 6件: Nitrogen metabolism, Proximal tubule bicarbonate reclamation, Collecting duct acid secretion, Gastric acid secretion, Pancreatic secretion, Bile secretion Acetazolamide sodium 💬 Acetazolamide 8件: 13, 67, 90, 115, 155, 222, 225, 230 💬
46 CCKBR 💬 4件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Gastric acid secretion Proglumide 💬 Proglumide 1件: 298 💬
47 CFTR 💬 9件: ABC transporters, cAMP signaling pathway, Phagocytosis, AMPK signaling pathway, Tight junction, Gastric acid secretion, Pancreatic secretion, Bile secretion, Vibrio cholerae infection Elexacaftor 💬 Elexacaftor 1件: 299 💬
48 CFTR 💬 9件: ABC transporters, cAMP signaling pathway, Phagocytosis, AMPK signaling pathway, Tight junction, Gastric acid secretion, Pancreatic secretion, Bile secretion, Vibrio cholerae infection Galicaftor 💬 Galicaftor 1件: 299 💬
49 CFTR 💬 9件: ABC transporters, cAMP signaling pathway, Phagocytosis, AMPK signaling pathway, Tight junction, Gastric acid secretion, Pancreatic secretion, Bile secretion, Vibrio cholerae infection Vanzacaftor 💬 Vanzacaftor 1件: 299 💬
50 CFTR 💬 9件: ABC transporters, cAMP signaling pathway, Phagocytosis, AMPK signaling pathway, Tight junction, Gastric acid secretion, Pancreatic secretion, Bile secretion, Vibrio cholerae infection Ivacaftor 💬 Ivacaftor 3件: 298, 299, 340 💬
51 CFTR 💬 9件: ABC transporters, cAMP signaling pathway, Phagocytosis, AMPK signaling pathway, Tight junction, Gastric acid secretion, Pancreatic secretion, Bile secretion, Vibrio cholerae infection Tezacaftor 💬 Tezacaftor 1件: 299 💬
52 CFTR 💬 9件: ABC transporters, cAMP signaling pathway, Phagocytosis, AMPK signaling pathway, Tight junction, Gastric acid secretion, Pancreatic secretion, Bile secretion, Vibrio cholerae infection Navocaftor 💬 Navocaftor 1件: 299 💬
53 CFTR 💬 9件: ABC transporters, cAMP signaling pathway, Phagocytosis, AMPK signaling pathway, Tight junction, Gastric acid secretion, Pancreatic secretion, Bile secretion, Vibrio cholerae infection Vanzacaftor calcium 💬 Vanzacaftor 1件: 299 💬
54 CFTR 💬 9件: ABC transporters, cAMP signaling pathway, Phagocytosis, AMPK signaling pathway, Tight junction, Gastric acid secretion, Pancreatic secretion, Bile secretion, Vibrio cholerae infection Deutivacaftor 💬 Deutivacaftor 1件: 299 💬
55 CFTR 💬 9件: ABC transporters, cAMP signaling pathway, Phagocytosis, AMPK signaling pathway, Tight junction, Gastric acid secretion, Pancreatic secretion, Bile secretion, Vibrio cholerae infection Lumacaftor 💬 Lumacaftor 1件: 299 💬
56 CFTR 💬 9件: ABC transporters, cAMP signaling pathway, Phagocytosis, AMPK signaling pathway, Tight junction, Gastric acid secretion, Pancreatic secretion, Bile secretion, Vibrio cholerae infection Icenticaftor 💬 Icenticaftor 1件: 299 💬
57 CHRM3 💬 12件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cholinergic synapse, Taste transduction, Regulation of actin cytoskeleton, Insulin secretion, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Alzheimer disease, Pathways of neurodegeneration - multiple diseases Blarcamesine hydrochloride 💬 Blarcamesine 1件: 156 💬
58 CHRM3 💬 12件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cholinergic synapse, Taste transduction, Regulation of actin cytoskeleton, Insulin secretion, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Alzheimer disease, Pathways of neurodegeneration - multiple diseases Solifenacin succinate 💬 Solifenacin 3件: 6, 13, 53 💬
59 CHRM3 💬 12件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cholinergic synapse, Taste transduction, Regulation of actin cytoskeleton, Insulin secretion, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Alzheimer disease, Pathways of neurodegeneration - multiple diseases Darifenacin hydrobromide 💬 Darifenacin 4件: 2, 6, 13, 26 💬
60 CHRM3 💬 12件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cholinergic synapse, Taste transduction, Regulation of actin cytoskeleton, Insulin secretion, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Alzheimer disease, Pathways of neurodegeneration - multiple diseases Propantheline bromide 💬 Propantheline 1件: 26 💬
61 CHRM3 💬 12件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cholinergic synapse, Taste transduction, Regulation of actin cytoskeleton, Insulin secretion, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Alzheimer disease, Pathways of neurodegeneration - multiple diseases Tropicamide 💬 Tropicamide 2件: 6, 19 💬
62 CHRM3 💬 12件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cholinergic synapse, Taste transduction, Regulation of actin cytoskeleton, Insulin secretion, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Alzheimer disease, Pathways of neurodegeneration - multiple diseases Pilocarpine nitrate 💬 Pilocarpine 3件: 6, 53, 299 💬
63 CHRM3 💬 12件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cholinergic synapse, Taste transduction, Regulation of actin cytoskeleton, Insulin secretion, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Alzheimer disease, Pathways of neurodegeneration - multiple diseases Pilocarpine 💬 Pilocarpine 3件: 6, 53, 299 💬
64 CHRM3 💬 12件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cholinergic synapse, Taste transduction, Regulation of actin cytoskeleton, Insulin secretion, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Alzheimer disease, Pathways of neurodegeneration - multiple diseases Cevimeline hydrochloride 💬 Cevimeline 1件: 53 💬
65 CHRM3 💬 12件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cholinergic synapse, Taste transduction, Regulation of actin cytoskeleton, Insulin secretion, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Alzheimer disease, Pathways of neurodegeneration - multiple diseases Scopolamine hydrobromide 💬 Scopolamine 1件: 2 💬
66 CHRM3 💬 12件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cholinergic synapse, Taste transduction, Regulation of actin cytoskeleton, Insulin secretion, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Alzheimer disease, Pathways of neurodegeneration - multiple diseases Fesoterodine fumarate 💬 Fesoterodine 1件: 6 💬
67 CHRM3 💬 12件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cholinergic synapse, Taste transduction, Regulation of actin cytoskeleton, Insulin secretion, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Alzheimer disease, Pathways of neurodegeneration - multiple diseases Solifenacin 💬 Solifenacin 3件: 6, 13, 53 💬
68 CHRM3 💬 12件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cholinergic synapse, Taste transduction, Regulation of actin cytoskeleton, Insulin secretion, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Alzheimer disease, Pathways of neurodegeneration - multiple diseases Tolterodine tartrate 💬 Tolterodine 2件: 17, 53 💬
69 CHRM3 💬 12件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cholinergic synapse, Taste transduction, Regulation of actin cytoskeleton, Insulin secretion, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Alzheimer disease, Pathways of neurodegeneration - multiple diseases Acetylcholine chloride 💬 Acetylcholine 1件: 11 💬
70 CHRM3 💬 12件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cholinergic synapse, Taste transduction, Regulation of actin cytoskeleton, Insulin secretion, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Alzheimer disease, Pathways of neurodegeneration - multiple diseases Oxybutynin 💬 Oxybutynin 3件: 6, 13, 53 💬
71 CHRM3 💬 12件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cholinergic synapse, Taste transduction, Regulation of actin cytoskeleton, Insulin secretion, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Alzheimer disease, Pathways of neurodegeneration - multiple diseases Chlorpromazine 💬 Chlorpromazine 2件: 120, 254 💬
72 CHRM3 💬 12件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cholinergic synapse, Taste transduction, Regulation of actin cytoskeleton, Insulin secretion, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Alzheimer disease, Pathways of neurodegeneration - multiple diseases Pilocarpine hydrochloride 💬 Pilocarpine 3件: 6, 53, 299 💬
73 CHRM3 💬 12件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cholinergic synapse, Taste transduction, Regulation of actin cytoskeleton, Insulin secretion, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Alzheimer disease, Pathways of neurodegeneration - multiple diseases Blarcamesine 💬 Blarcamesine 1件: 156 💬
74 CHRM3 💬 12件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cholinergic synapse, Taste transduction, Regulation of actin cytoskeleton, Insulin secretion, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Alzheimer disease, Pathways of neurodegeneration - multiple diseases Rocuronium bromide 💬 Rocuronium 2件: 70, 296 💬
75 CHRM3 💬 12件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cholinergic synapse, Taste transduction, Regulation of actin cytoskeleton, Insulin secretion, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Alzheimer disease, Pathways of neurodegeneration - multiple diseases Tolterodine 💬 Tolterodine 2件: 17, 53 💬
76 CHRM3 💬 12件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cholinergic synapse, Taste transduction, Regulation of actin cytoskeleton, Insulin secretion, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Alzheimer disease, Pathways of neurodegeneration - multiple diseases Atropine sulfate 💬 Atropine 1件: 2 💬
77 CHRM3 💬 12件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cholinergic synapse, Taste transduction, Regulation of actin cytoskeleton, Insulin secretion, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Alzheimer disease, Pathways of neurodegeneration - multiple diseases Methacholine chloride 💬 Methacholine 2件: 96, 340 💬
78 CHRM3 💬 12件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cholinergic synapse, Taste transduction, Regulation of actin cytoskeleton, Insulin secretion, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Alzheimer disease, Pathways of neurodegeneration - multiple diseases Scopolamine 💬 Scopolamine 1件: 2 💬
79 CHRM3 💬 12件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cholinergic synapse, Taste transduction, Regulation of actin cytoskeleton, Insulin secretion, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Alzheimer disease, Pathways of neurodegeneration - multiple diseases Propiverine hydrochloride 💬 Propiverine 1件: 226 💬
80 CHRM3 💬 12件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cholinergic synapse, Taste transduction, Regulation of actin cytoskeleton, Insulin secretion, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Alzheimer disease, Pathways of neurodegeneration - multiple diseases Trihexyphenidyl hydrochloride 💬 Trihexyphenidyl 2件: 5, 6 💬
81 CHRM3 💬 12件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cholinergic synapse, Taste transduction, Regulation of actin cytoskeleton, Insulin secretion, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Alzheimer disease, Pathways of neurodegeneration - multiple diseases Propiverine 💬 Propiverine 1件: 226 💬
82 CHRM3 💬 12件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cholinergic synapse, Taste transduction, Regulation of actin cytoskeleton, Insulin secretion, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Alzheimer disease, Pathways of neurodegeneration - multiple diseases Fesoterodine 💬 Fesoterodine 1件: 6 💬
83 CHRM3 💬 12件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cholinergic synapse, Taste transduction, Regulation of actin cytoskeleton, Insulin secretion, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Alzheimer disease, Pathways of neurodegeneration - multiple diseases Bethanechol chloride 💬 Bethanechol 1件: 98 💬
84 CHRM3 💬 12件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cholinergic synapse, Taste transduction, Regulation of actin cytoskeleton, Insulin secretion, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Alzheimer disease, Pathways of neurodegeneration - multiple diseases Oxybutynin chloride 💬 Oxybutynin 3件: 6, 13, 53 💬
85 CHRM3 💬 12件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cholinergic synapse, Taste transduction, Regulation of actin cytoskeleton, Insulin secretion, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Alzheimer disease, Pathways of neurodegeneration - multiple diseases Tiotropium bromide hydrate 💬 Tiotropium 3件: 55, 85, 299 💬
86 CHRM3 💬 12件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cholinergic synapse, Taste transduction, Regulation of actin cytoskeleton, Insulin secretion, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Alzheimer disease, Pathways of neurodegeneration - multiple diseases Atropine 💬 Atropine 1件: 2 💬
87 CHRM3 💬 12件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cholinergic synapse, Taste transduction, Regulation of actin cytoskeleton, Insulin secretion, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Alzheimer disease, Pathways of neurodegeneration - multiple diseases Cevimeline 💬 Cevimeline 1件: 53 💬
88 CHRM3 💬 12件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cholinergic synapse, Taste transduction, Regulation of actin cytoskeleton, Insulin secretion, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Alzheimer disease, Pathways of neurodegeneration - multiple diseases Darifenacin 💬 Darifenacin 4件: 2, 6, 13, 26 💬
89 CHRM3 💬 12件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cholinergic synapse, Taste transduction, Regulation of actin cytoskeleton, Insulin secretion, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Alzheimer disease, Pathways of neurodegeneration - multiple diseases Chlorpromazine hydrochloride 💬 Chlorpromazine 2件: 120, 254 💬
90 CHRM3 💬 12件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cholinergic synapse, Taste transduction, Regulation of actin cytoskeleton, Insulin secretion, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Alzheimer disease, Pathways of neurodegeneration - multiple diseases Trihexyphenidyl 💬 Trihexyphenidyl 2件: 5, 6 💬
91 HRH2 💬 4件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Gastric acid secretion Histamine phosphate 💬 Histamine 1件: 13 💬
92 HRH2 💬 4件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Gastric acid secretion Cimetidine hydrochloride 💬 Cimetidine 2件: 2, 254 💬
93 HRH2 💬 4件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Gastric acid secretion Cimetidine 💬 Cimetidine 2件: 2, 254 💬
94 HRH2 💬 4件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Gastric acid secretion Ranitidine 💬 Ranitidine 2件: 13, 65 💬
95 HRH2 💬 4件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Gastric acid secretion Ranitidine hydrochloride 💬 Ranitidine 2件: 13, 65 💬
96 HRH2 💬 4件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Gastric acid secretion Histamine 💬 Histamine 1件: 13 💬
97 HRH2 💬 4件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Gastric acid secretion Ranitidine bismuth citrate 💬 Ranitidine 2件: 13, 65 💬
98 HRH2 💬 4件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Gastric acid secretion Famotidine 💬 Famotidine 7件: 6, 46, 86, 98, 107, 145, 300 💬
99 KCNQ1 💬 6件: Adrenergic signaling in cardiomyocytes, Cholinergic synapse, Gastric acid secretion, Pancreatic secretion, Protein digestion and absorption, Vibrio cholerae infection Amiodarone hydrochloride 💬 Amiodarone 3件: 28, 67, 127 💬
100 KCNQ1 💬 6件: Adrenergic signaling in cardiomyocytes, Cholinergic synapse, Gastric acid secretion, Pancreatic secretion, Protein digestion and absorption, Vibrio cholerae infection Amiodarone 💬 Amiodarone 3件: 28, 67, 127 💬
101 KCNQ1 💬 6件: Adrenergic signaling in cardiomyocytes, Cholinergic synapse, Gastric acid secretion, Pancreatic secretion, Protein digestion and absorption, Vibrio cholerae infection Ezogabine 💬 Ezogabine 2件: 2, 144 💬
102 PRKCB 💬 72件: MAPK signaling pathway, ErbB signaling pathway, Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, Chemokine signaling pathway, NF-kappa B signaling pathway, HIF-1 signaling pathway, Phosphatidylinositol signaling system, Sphingolipid signaling pathway, Neuroactive ligand signaling, mTOR signaling pathway, Vascular smooth muscle contraction, Wnt signaling pathway, VEGF signaling pathway, Focal adhesion, IgSF CAM signaling, Gap junction, Neutrophil extracellular trap formation, Natural killer cell mediated cytotoxicity, B cell receptor signaling pathway, Fc gamma R-mediated phagosome formation, Leukocyte transendothelial migration, Circadian entrainment, Long-term potentiation, Retrograde endocannabinoid signaling, Glutamatergic synapse, Cholinergic synapse, Serotonergic synapse, GABAergic synapse, Dopaminergic synapse, Long-term depression, Inflammatory mediator regulation of TRP channels, Insulin secretion, GnRH signaling pathway, Melanogenesis, Thyroid hormone synthesis, Thyroid hormone signaling pathway, Oxytocin signaling pathway, Aldosterone synthesis and secretion, Parathyroid hormone synthesis, secretion and action, GnRH secretion, Insulin resistance, AGE-RAGE signaling pathway in diabetic complications, Growth hormone synthesis, secretion and action, Aldosterone-regulated sodium reabsorption, Endocrine and other factor-regulated calcium reabsorption, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Carbohydrate digestion and absorption, Spinocerebellar ataxia, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Morphine addiction, Leishmaniasis, African trypanosomiasis, Amoebiasis, Hepatitis B, Human cytomegalovirus infection, Influenza A, Human immunodeficiency virus 1 infection, Coronavirus disease, Pathways in cancer, Proteoglycans in cancer, MicroRNAs in cancer, Chemical carcinogenesis - receptor activation, Glioma, Non-small cell lung cancer, Hepatocellular carcinoma, Choline metabolism in cancer, Diabetic cardiomyopathy Enzastaurin hydrochloride 💬 Enzastaurin 1件: 168 💬
103 PRKCB 💬 72件: MAPK signaling pathway, ErbB signaling pathway, Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, Chemokine signaling pathway, NF-kappa B signaling pathway, HIF-1 signaling pathway, Phosphatidylinositol signaling system, Sphingolipid signaling pathway, Neuroactive ligand signaling, mTOR signaling pathway, Vascular smooth muscle contraction, Wnt signaling pathway, VEGF signaling pathway, Focal adhesion, IgSF CAM signaling, Gap junction, Neutrophil extracellular trap formation, Natural killer cell mediated cytotoxicity, B cell receptor signaling pathway, Fc gamma R-mediated phagosome formation, Leukocyte transendothelial migration, Circadian entrainment, Long-term potentiation, Retrograde endocannabinoid signaling, Glutamatergic synapse, Cholinergic synapse, Serotonergic synapse, GABAergic synapse, Dopaminergic synapse, Long-term depression, Inflammatory mediator regulation of TRP channels, Insulin secretion, GnRH signaling pathway, Melanogenesis, Thyroid hormone synthesis, Thyroid hormone signaling pathway, Oxytocin signaling pathway, Aldosterone synthesis and secretion, Parathyroid hormone synthesis, secretion and action, GnRH secretion, Insulin resistance, AGE-RAGE signaling pathway in diabetic complications, Growth hormone synthesis, secretion and action, Aldosterone-regulated sodium reabsorption, Endocrine and other factor-regulated calcium reabsorption, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Carbohydrate digestion and absorption, Spinocerebellar ataxia, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Morphine addiction, Leishmaniasis, African trypanosomiasis, Amoebiasis, Hepatitis B, Human cytomegalovirus infection, Influenza A, Human immunodeficiency virus 1 infection, Coronavirus disease, Pathways in cancer, Proteoglycans in cancer, MicroRNAs in cancer, Chemical carcinogenesis - receptor activation, Glioma, Non-small cell lung cancer, Hepatocellular carcinoma, Choline metabolism in cancer, Diabetic cardiomyopathy Enzastaurin 💬 Enzastaurin 1件: 168 💬
104 SSTR2 💬 5件: cAMP signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Growth hormone synthesis, secretion and action, Gastric acid secretion Lanreotide acetate 💬 Lanreotide 5件: 67, 73, 77, 85, 298 💬
105 SSTR2 💬 5件: cAMP signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Growth hormone synthesis, secretion and action, Gastric acid secretion Pasireotide 💬 Pasireotide 4件: 67, 74, 75, 77 💬
106 SSTR2 💬 5件: cAMP signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Growth hormone synthesis, secretion and action, Gastric acid secretion Pasireotide diaspartate 💬 Pasireotide 4件: 67, 74, 75, 77 💬
107 SSTR2 💬 5件: cAMP signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Growth hormone synthesis, secretion and action, Gastric acid secretion Octreotide acetate 💬 Octreotide 8件: 67, 75, 77, 84, 85, 89, 193, 227 💬
108 SSTR2 💬 5件: cAMP signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Growth hormone synthesis, secretion and action, Gastric acid secretion Somatostatin 💬 Somatostatin 2件: 67, 77 💬
109 SSTR2 💬 5件: cAMP signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Growth hormone synthesis, secretion and action, Gastric acid secretion Octreotide hydrochloride 💬 Octreotide 8件: 67, 75, 77, 84, 85, 89, 193, 227 💬
110 SSTR2 💬 5件: cAMP signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Growth hormone synthesis, secretion and action, Gastric acid secretion Pasireotide pamoate 💬 Pasireotide 4件: 67, 74, 75, 77 💬
111 SSTR2 💬 5件: cAMP signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Growth hormone synthesis, secretion and action, Gastric acid secretion Paltusotine 💬 Paltusotine 1件: 77 💬
112 SSTR2 💬 5件: cAMP signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Growth hormone synthesis, secretion and action, Gastric acid secretion Paltusotine hydrochloride 💬 Paltusotine 1件: 77 💬
113 SSTR2 💬 5件: cAMP signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Growth hormone synthesis, secretion and action, Gastric acid secretion Octreotide pamoate 💬 Octreotide 8件: 67, 75, 77, 84, 85, 89, 193, 227 💬
114 SSTR2 💬 5件: cAMP signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Growth hormone synthesis, secretion and action, Gastric acid secretion Octreotide acetate 💬 Octreotide 8件: 67, 75, 77, 84, 85, 89, 193, 227 💬
115 SSTR2 💬 5件: cAMP signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Growth hormone synthesis, secretion and action, Gastric acid secretion Octreotide 💬 Octreotide 8件: 67, 75, 77, 84, 85, 89, 193, 227 💬