Target Gene/Pathway Pathway / Gene

  

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No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank 指定難病告示番号
1 ACHE 💬 3件: Glycerophospholipid metabolism, Neuroactive ligand signaling, Cholinergic synapse Donepezil hydrochloride 💬 Donepezil 8件: 5, 6, 13, 46, 124, 127, 156, 206 💬
2 ACHE 💬 3件: Glycerophospholipid metabolism, Neuroactive ligand signaling, Cholinergic synapse Galantamine 💬 Galantamine 3件: 6, 11, 127 💬
3 ACHE 💬 3件: Glycerophospholipid metabolism, Neuroactive ligand signaling, Cholinergic synapse Galantamine hydrobromide 💬 Galantamine 3件: 6, 11, 127 💬
4 ACHE 💬 3件: Glycerophospholipid metabolism, Neuroactive ligand signaling, Cholinergic synapse Donepezil 💬 Donepezil 8件: 5, 6, 13, 46, 124, 127, 156, 206 💬
5 ADRA1A 💬 9件: Calcium signaling pathway, cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Salivary secretion Amiodarone hydrochloride 💬 Amiodarone 3件: 28, 67, 127 💬
6 ADRA1A 💬 9件: Calcium signaling pathway, cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Salivary secretion Amiodarone 💬 Amiodarone 3件: 28, 67, 127 💬
7 ADRA1B 💬 8件: Calcium signaling pathway, cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Salivary secretion Amiodarone 💬 Amiodarone 3件: 28, 67, 127 💬
8 ADRA1B 💬 8件: Calcium signaling pathway, cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Salivary secretion Amiodarone hydrochloride 💬 Amiodarone 3件: 28, 67, 127 💬
9 ADRA1D 💬 8件: Calcium signaling pathway, cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Salivary secretion Amiodarone hydrochloride 💬 Amiodarone 3件: 28, 67, 127 💬
10 ADRA1D 💬 8件: Calcium signaling pathway, cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Salivary secretion Amiodarone 💬 Amiodarone 3件: 28, 67, 127 💬
11 ADRB1 💬 13件: Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Adrenergic signaling in cardiomyocytes, Gap junction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy Amiodarone 💬 Amiodarone 3件: 28, 67, 127 💬
12 ADRB1 💬 13件: Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Adrenergic signaling in cardiomyocytes, Gap junction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy Amiodarone hydrochloride 💬 Amiodarone 3件: 28, 67, 127 💬
13 CNR1 💬 4件: Rap1 signaling pathway, Neuroactive ligand-receptor interaction, Thermogenesis, Retrograde endocannabinoid signaling Nabilone 💬 Nabilone 4件: 6, 13, 97, 127 💬
14 CNR2 💬 1件: Neuroactive ligand-receptor interaction Nabilone 💬 Nabilone 4件: 6, 13, 97, 127 💬
15 COMT 💬 3件: Steroid hormone biosynthesis, Tyrosine metabolism, Dopaminergic synapse Tolcapone 💬 Tolcapone 3件: 6, 28, 127 💬
16 DRD2 💬 10件: Rap1 signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Alcoholism Rotigotine 💬 Rotigotine 3件: 6, 67, 127 💬
17 GRIN1 💬 19件: Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Huntington disease, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism Amantadine hydrochloride 💬 Amantadine 5件: 2, 6, 8, 13, 127 💬
18 GRIN1 💬 19件: Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Huntington disease, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism Memantine hydrochloride 💬 Memantine 8件: 2, 6, 8, 13, 49, 127, 205, 206 💬
19 GRIN1 💬 19件: Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Huntington disease, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism Amantadine 💬 Amantadine 5件: 2, 6, 8, 13, 127 💬
20 GRIN1 💬 19件: Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Huntington disease, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism Memantine 💬 Memantine 8件: 2, 6, 8, 13, 49, 127, 205, 206 💬
21 GRIN2A 💬 20件: Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Dopaminergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism, Systemic lupus erythematosus Memantine hydrochloride 💬 Memantine 8件: 2, 6, 8, 13, 49, 127, 205, 206 💬
22 GRIN2A 💬 20件: Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Dopaminergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism, Systemic lupus erythematosus Amantadine hydrochloride 💬 Amantadine 5件: 2, 6, 8, 13, 127 💬
23 GRIN2A 💬 20件: Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Dopaminergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism, Systemic lupus erythematosus Memantine 💬 Memantine 8件: 2, 6, 8, 13, 49, 127, 205, 206 💬
24 GRIN2A 💬 20件: Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Dopaminergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism, Systemic lupus erythematosus Amantadine 💬 Amantadine 5件: 2, 6, 8, 13, 127 💬
25 GRIN2B 💬 21件: Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Dopaminergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Huntington disease, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism, Systemic lupus erythematosus Memantine 💬 Memantine 8件: 2, 6, 8, 13, 49, 127, 205, 206 💬
26 GRIN2B 💬 21件: Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Dopaminergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Huntington disease, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism, Systemic lupus erythematosus Amantadine hydrochloride 💬 Amantadine 5件: 2, 6, 8, 13, 127 💬
27 GRIN2B 💬 21件: Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Dopaminergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Huntington disease, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism, Systemic lupus erythematosus Amantadine 💬 Amantadine 5件: 2, 6, 8, 13, 127 💬
28 GRIN2B 💬 21件: Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Dopaminergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Huntington disease, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism, Systemic lupus erythematosus Memantine hydrochloride 💬 Memantine 8件: 2, 6, 8, 13, 49, 127, 205, 206 💬
29 GRIN2C 💬 16件: Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism Memantine 💬 Memantine 8件: 2, 6, 8, 13, 49, 127, 205, 206 💬
30 GRIN2C 💬 16件: Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism Amantadine 💬 Amantadine 5件: 2, 6, 8, 13, 127 💬
31 GRIN2C 💬 16件: Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism Amantadine hydrochloride 💬 Amantadine 5件: 2, 6, 8, 13, 127 💬
32 GRIN2C 💬 16件: Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism Memantine hydrochloride 💬 Memantine 8件: 2, 6, 8, 13, 49, 127, 205, 206 💬
33 GRIN2D 💬 16件: Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism Amantadine hydrochloride 💬 Amantadine 5件: 2, 6, 8, 13, 127 💬
34 GRIN2D 💬 16件: Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism Memantine 💬 Memantine 8件: 2, 6, 8, 13, 49, 127, 205, 206 💬
35 GRIN2D 💬 16件: Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism Memantine hydrochloride 💬 Memantine 8件: 2, 6, 8, 13, 49, 127, 205, 206 💬
36 GRIN2D 💬 16件: Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Circadian entrainment, Long-term potentiation, Glutamatergic synapse, Alzheimer disease, Amyotrophic lateral sclerosis, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Nicotine addiction, Alcoholism Amantadine 💬 Amantadine 5件: 2, 6, 8, 13, 127 💬
37 HCRTR1 💬 2件: Neuroactive ligand-receptor interaction, Hormone signaling Lemborexant 💬 Lemborexant 2件: 6, 127 💬
38 HCRTR2 💬 2件: Neuroactive ligand-receptor interaction, Hormone signaling Lemborexant 💬 Lemborexant 2件: 6, 127 💬
39 HTR1A 💬 5件: cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Serotonergic synapse, Taste transduction Vortioxetine hemihydrobromide 💬 Vortioxetine 2件: 6, 127 💬
40 HTR1A 💬 5件: cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Serotonergic synapse, Taste transduction Vortioxetine 💬 Vortioxetine 2件: 6, 127 💬
41 HTR1A 💬 5件: cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Serotonergic synapse, Taste transduction Vortioxetine hydrobromide 💬 Vortioxetine 2件: 6, 127 💬
42 HTR3A 💬 3件: Neuroactive ligand signaling, Serotonergic synapse, Taste transduction Vortioxetine hydrobromide 💬 Vortioxetine 2件: 6, 127 💬
43 HTR3A 💬 3件: Neuroactive ligand signaling, Serotonergic synapse, Taste transduction Vortioxetine hemihydrobromide 💬 Vortioxetine 2件: 6, 127 💬
44 HTR3A 💬 3件: Neuroactive ligand signaling, Serotonergic synapse, Taste transduction Vortioxetine 💬 Vortioxetine 2件: 6, 127 💬
45 HTR3B 💬 3件: Neuroactive ligand signaling, Serotonergic synapse, Taste transduction Vortioxetine 💬 Vortioxetine 2件: 6, 127 💬
46 HTR3B 💬 3件: Neuroactive ligand signaling, Serotonergic synapse, Taste transduction Vortioxetine hemihydrobromide 💬 Vortioxetine 2件: 6, 127 💬
47 HTR3B 💬 3件: Neuroactive ligand signaling, Serotonergic synapse, Taste transduction Vortioxetine hydrobromide 💬 Vortioxetine 2件: 6, 127 💬
48 HTR3C 💬 3件: Neuroactive ligand signaling, Serotonergic synapse, Taste transduction Vortioxetine hemihydrobromide 💬 Vortioxetine 2件: 6, 127 💬
49 HTR3C 💬 3件: Neuroactive ligand signaling, Serotonergic synapse, Taste transduction Vortioxetine 💬 Vortioxetine 2件: 6, 127 💬
50 HTR3C 💬 3件: Neuroactive ligand signaling, Serotonergic synapse, Taste transduction Vortioxetine hydrobromide 💬 Vortioxetine 2件: 6, 127 💬
51 HTR3D 💬 3件: Neuroactive ligand signaling, Serotonergic synapse, Taste transduction Vortioxetine hemihydrobromide 💬 Vortioxetine 2件: 6, 127 💬
52 HTR3D 💬 3件: Neuroactive ligand signaling, Serotonergic synapse, Taste transduction Vortioxetine 💬 Vortioxetine 2件: 6, 127 💬
53 HTR3D 💬 3件: Neuroactive ligand signaling, Serotonergic synapse, Taste transduction Vortioxetine hydrobromide 💬 Vortioxetine 2件: 6, 127 💬
54 HTR3E 💬 3件: Neuroactive ligand signaling, Serotonergic synapse, Taste transduction Vortioxetine 💬 Vortioxetine 2件: 6, 127 💬
55 HTR3E 💬 3件: Neuroactive ligand signaling, Serotonergic synapse, Taste transduction Vortioxetine hydrobromide 💬 Vortioxetine 2件: 6, 127 💬
56 HTR3E 💬 3件: Neuroactive ligand signaling, Serotonergic synapse, Taste transduction Vortioxetine hemihydrobromide 💬 Vortioxetine 2件: 6, 127 💬
57 KCND3 💬 1件: Spinocerebellar ataxia Amiodarone 💬 Amiodarone 3件: 28, 67, 127 💬
58 KCND3 💬 1件: Spinocerebellar ataxia Amiodarone hydrochloride 💬 Amiodarone 3件: 28, 67, 127 💬
59 KCNJ11 💬 3件: Insulin secretion, GnRH secretion, Type II diabetes mellitus Amiodarone hydrochloride 💬 Amiodarone 3件: 28, 67, 127 💬
60 KCNJ11 💬 3件: Insulin secretion, GnRH secretion, Type II diabetes mellitus Amiodarone 💬 Amiodarone 3件: 28, 67, 127 💬
61 KCNJ12 💬 2件: Cholinergic synapse, Oxytocin signaling pathway Amiodarone hydrochloride 💬 Amiodarone 3件: 28, 67, 127 💬
62 KCNJ12 💬 2件: Cholinergic synapse, Oxytocin signaling pathway Amiodarone 💬 Amiodarone 3件: 28, 67, 127 💬
63 KCNJ3 💬 10件: Circadian entrainment, Retrograde endocannabinoid signaling, Glutamatergic synapse, Cholinergic synapse, Serotonergic synapse, Dopaminergic synapse, Estrogen signaling pathway, Oxytocin signaling pathway, GnRH secretion, Morphine addiction Amiodarone hydrochloride 💬 Amiodarone 3件: 28, 67, 127 💬
64 KCNJ3 💬 10件: Circadian entrainment, Retrograde endocannabinoid signaling, Glutamatergic synapse, Cholinergic synapse, Serotonergic synapse, Dopaminergic synapse, Estrogen signaling pathway, Oxytocin signaling pathway, GnRH secretion, Morphine addiction Amiodarone 💬 Amiodarone 3件: 28, 67, 127 💬
65 KCNJ5 💬 9件: Circadian entrainment, Retrograde endocannabinoid signaling, Serotonergic synapse, Dopaminergic synapse, Estrogen signaling pathway, Oxytocin signaling pathway, Aldosterone synthesis and secretion, GnRH secretion, Morphine addiction Amiodarone hydrochloride 💬 Amiodarone 3件: 28, 67, 127 💬
66 KCNJ5 💬 9件: Circadian entrainment, Retrograde endocannabinoid signaling, Serotonergic synapse, Dopaminergic synapse, Estrogen signaling pathway, Oxytocin signaling pathway, Aldosterone synthesis and secretion, GnRH secretion, Morphine addiction Amiodarone 💬 Amiodarone 3件: 28, 67, 127 💬
67 KCNJ8 💬 1件: cGMP-PKG signaling pathway Amiodarone 💬 Amiodarone 3件: 28, 67, 127 💬
68 KCNJ8 💬 1件: cGMP-PKG signaling pathway Amiodarone hydrochloride 💬 Amiodarone 3件: 28, 67, 127 💬
69 KCNQ1 💬 6件: Adrenergic signaling in cardiomyocytes, Cholinergic synapse, Gastric acid secretion, Pancreatic secretion, Protein digestion and absorption, Vibrio cholerae infection Amiodarone 💬 Amiodarone 3件: 28, 67, 127 💬
70 KCNQ1 💬 6件: Adrenergic signaling in cardiomyocytes, Cholinergic synapse, Gastric acid secretion, Pancreatic secretion, Protein digestion and absorption, Vibrio cholerae infection Amiodarone hydrochloride 💬 Amiodarone 3件: 28, 67, 127 💬
71 MAPT 💬 4件: MAPK signaling pathway, Alzheimer disease, Parkinson disease, Pathways of neurodegeneration - multiple diseases Flortaucipir F 18 💬 Flortaucipir 3件: 5, 7, 127 💬
72 MPO 💬 5件: Drug metabolism - other enzymes, Phagocytosis, Neutrophil extracellular trap formation, Transcriptional misregulation in cancer, Acute myeloid leukemia Verdiperstat 💬 Verdiperstat 3件: 2, 17, 127 💬
73 MTOR 💬 52件: ErbB signaling pathway, HIF-1 signaling pathway, Phospholipase D signaling pathway, Autophagy - other, Autophagy - animal, Lysosome biogenesis, mTOR signaling pathway, PI3K-Akt signaling pathway, AMPK signaling pathway, Integrated stress response (ISR) signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Cellular senescence, Apelin signaling pathway, Integrin signaling, Neutrophil extracellular trap formation, JAK-STAT signaling pathway, Th17 cell differentiation, Thermogenesis, Insulin signaling pathway, Thyroid hormone signaling pathway, Adipocytokine signaling pathway, Type II diabetes mellitus, Insulin resistance, Growth hormone synthesis, secretion and action, Alzheimer disease, Amyotrophic lateral sclerosis, Huntington disease, Spinocerebellar ataxia, Pathways of neurodegeneration - multiple diseases, Shigellosis, Human cytomegalovirus infection, Human papillomavirus infection, Kaposi sarcoma-associated herpesvirus infection, Herpes simplex virus 1 infection, Human immunodeficiency virus 1 infection, Pathways in cancer, Proteoglycans in cancer, MicroRNAs in cancer, Chemical carcinogenesis - receptor activation, Colorectal cancer, Pancreatic cancer, Glioma, Prostate cancer, Acute myeloid leukemia, Breast cancer, Hepatocellular carcinoma, Gastric cancer, Central carbon metabolism in cancer, Choline metabolism in cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer, Diabetic cardiomyopathy Sirolimus 💬 Sirolimus 46件: 6, 13, 15, 17, 19, 21, 34, 35, 36, 46, 48, 49, 51, 54, 57, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 97, 98, 111, 127, 137, 157, 158, 192, 222, 223, 227, 277, 278, 279, 280, 281, 283, 285, 300, 331 💬
74 NR3C1 💬 1件: Neuroactive ligand-receptor interaction Prednisone 💬 Prednisone 58件: 2, 11, 13, 14, 18, 19, 26, 28, 35, 40, 41, 42, 43, 44, 45, 46, 48, 49, 50, 51, 53, 60, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 90, 93, 95, 96, 97, 113, 127, 145, 162, 164, 205, 222, 223, 224, 228, 251, 269, 283, 284, 285, 288, 299, 300, 303, 307, 331 💬
75 NR3C1 💬 1件: Neuroactive ligand-receptor interaction Methylprednisolone acetate 💬 Methylprednisolone 51件: 2, 6, 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 95, 96, 97, 111, 127, 145, 162, 164, 211, 222, 223, 224, 271, 283, 284, 285, 296, 300 💬
76 NR3C1 💬 1件: Neuroactive ligand-receptor interaction Methylprednisolone 💬 Methylprednisolone 51件: 2, 6, 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 95, 96, 97, 111, 127, 145, 162, 164, 211, 222, 223, 224, 271, 283, 284, 285, 296, 300 💬
77 OXTR 💬 5件: Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Oxytocin signaling pathway Oxytocin 💬 Oxytocin 8件: 6, 70, 72, 127, 168, 193, 206, 226 💬
78 PRKAA1 💬 20件: FoxO signaling pathway, Autophagy - animal, mTOR signaling pathway, PI3K-Akt signaling pathway, AMPK signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Apelin signaling pathway, Tight junction, Circadian rhythm, Thermogenesis, Insulin signaling pathway, Adipocytokine signaling pathway, Oxytocin signaling pathway, Glucagon signaling pathway, Insulin resistance, Non-alcoholic fatty liver disease, Alcoholic liver disease, Hypertrophic cardiomyopathy, Fluid shear stress and atherosclerosis Metformin hydrochloride 💬 Metformin 31件: 2, 6, 8, 13, 46, 49, 60, 65, 66, 67, 74, 75, 77, 81, 84, 85, 86, 97, 113, 127, 158, 206, 218, 222, 225, 233, 265, 285, 298, 299, 301 💬
79 PRKAA1 💬 20件: FoxO signaling pathway, Autophagy - animal, mTOR signaling pathway, PI3K-Akt signaling pathway, AMPK signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Apelin signaling pathway, Tight junction, Circadian rhythm, Thermogenesis, Insulin signaling pathway, Adipocytokine signaling pathway, Oxytocin signaling pathway, Glucagon signaling pathway, Insulin resistance, Non-alcoholic fatty liver disease, Alcoholic liver disease, Hypertrophic cardiomyopathy, Fluid shear stress and atherosclerosis Metformin 💬 Metformin 31件: 2, 6, 8, 13, 46, 49, 60, 65, 66, 67, 74, 75, 77, 81, 84, 85, 86, 97, 113, 127, 158, 206, 218, 222, 225, 233, 265, 285, 298, 299, 301 💬
80 PRKAA2 💬 20件: FoxO signaling pathway, Autophagy - animal, mTOR signaling pathway, PI3K-Akt signaling pathway, AMPK signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Apelin signaling pathway, Tight junction, Circadian rhythm, Thermogenesis, Insulin signaling pathway, Adipocytokine signaling pathway, Oxytocin signaling pathway, Glucagon signaling pathway, Insulin resistance, Non-alcoholic fatty liver disease, Alcoholic liver disease, Hypertrophic cardiomyopathy, Fluid shear stress and atherosclerosis Metformin hydrochloride 💬 Metformin 31件: 2, 6, 8, 13, 46, 49, 60, 65, 66, 67, 74, 75, 77, 81, 84, 85, 86, 97, 113, 127, 158, 206, 218, 222, 225, 233, 265, 285, 298, 299, 301 💬
81 PRKAA2 💬 20件: FoxO signaling pathway, Autophagy - animal, mTOR signaling pathway, PI3K-Akt signaling pathway, AMPK signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Apelin signaling pathway, Tight junction, Circadian rhythm, Thermogenesis, Insulin signaling pathway, Adipocytokine signaling pathway, Oxytocin signaling pathway, Glucagon signaling pathway, Insulin resistance, Non-alcoholic fatty liver disease, Alcoholic liver disease, Hypertrophic cardiomyopathy, Fluid shear stress and atherosclerosis Metformin 💬 Metformin 31件: 2, 6, 8, 13, 46, 49, 60, 65, 66, 67, 74, 75, 77, 81, 84, 85, 86, 97, 113, 127, 158, 206, 218, 222, 225, 233, 265, 285, 298, 299, 301 💬
82 SCN1A 💬 1件: Dopaminergic synapse Amiodarone hydrochloride 💬 Amiodarone 3件: 28, 67, 127 💬
83 SCN1A 💬 1件: Dopaminergic synapse Amiodarone 💬 Amiodarone 3件: 28, 67, 127 💬
84 SCN2A 💬 1件: Taste transduction Amiodarone 💬 Amiodarone 3件: 28, 67, 127 💬
85 SCN2A 💬 1件: Taste transduction Amiodarone hydrochloride 💬 Amiodarone 3件: 28, 67, 127 💬
86 SCN3A 💬 1件: Taste transduction Amiodarone 💬 Amiodarone 3件: 28, 67, 127 💬
87 SCN3A 💬 1件: Taste transduction Amiodarone hydrochloride 💬 Amiodarone 3件: 28, 67, 127 💬
88 SCN5A 💬 2件: Adrenergic signaling in cardiomyocytes, Cadherin signaling Amiodarone hydrochloride 💬 Amiodarone 3件: 28, 67, 127 💬
89 SCN5A 💬 2件: Adrenergic signaling in cardiomyocytes, Cadherin signaling Amiodarone 💬 Amiodarone 3件: 28, 67, 127 💬
90 SCN8A 💬 1件: IgSF CAM signaling Amiodarone hydrochloride 💬 Amiodarone 3件: 28, 67, 127 💬
91 SCN8A 💬 1件: IgSF CAM signaling Amiodarone 💬 Amiodarone 3件: 28, 67, 127 💬
92 SCN9A 💬 1件: Taste transduction Amiodarone 💬 Amiodarone 3件: 28, 67, 127 💬
93 SCN9A 💬 1件: Taste transduction Amiodarone hydrochloride 💬 Amiodarone 3件: 28, 67, 127 💬
94 SLC6A4 💬 3件: Neuroactive ligand signaling, Synaptic vesicle cycle, Serotonergic synapse Vortioxetine 💬 Vortioxetine 2件: 6, 127 💬
95 SLC6A4 💬 3件: Neuroactive ligand signaling, Synaptic vesicle cycle, Serotonergic synapse Vortioxetine hemihydrobromide 💬 Vortioxetine 2件: 6, 127 💬
96 SLC6A4 💬 3件: Neuroactive ligand signaling, Synaptic vesicle cycle, Serotonergic synapse Vortioxetine hydrobromide 💬 Vortioxetine 2件: 6, 127 💬
97 SLC6A4 💬 3件: Neuroactive ligand signaling, Synaptic vesicle cycle, Serotonergic synapse Citalopram 💬 Citalopram 7件: 6, 8, 13, 18, 46, 98, 127 💬
98 SLC6A4 💬 3件: Neuroactive ligand signaling, Synaptic vesicle cycle, Serotonergic synapse Citalopram hydrobromide 💬 Citalopram 7件: 6, 8, 13, 18, 46, 98, 127 💬
99 SORT1 💬 3件: Lysosome biogenesis, Neurotrophin signaling pathway, Cholesterol metabolism Latozinemab 💬 Latozinemab 1件: 127 💬