Target Gene/Pathway Pathway / Gene

  

Search results

No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank Disease ID
1 MTOR [5] Th17 cell differentiation, Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus, Spinocerebellar ataxia D00753 Sirolimus [40] 2, 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331
2 MTOR [5] Th17 cell differentiation, Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus, Spinocerebellar ataxia D02714 Everolimus [9] 34, 67, 89, 96, 137, 157, 158, 228, 277
3 MTOR [5] Th17 cell differentiation, Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus, Spinocerebellar ataxia D06068 Temsirolimus [1] 13
4 GRIA1 [1] Spinocerebellar ataxia D00537 Topiramate [6] 6, 97, 140, 144, 156, 193
5 GRIA1 [1] Spinocerebellar ataxia D00775 Riluzole [9] 2, 3, 5, 8, 13, 17, 18, 203, 206
6 GRIA1 [1] Spinocerebellar ataxia D02696 Talampanel [2] 2, 6
7 GRIA1 [1] Spinocerebellar ataxia D08964 Perampanel [3] 2, 6, 144
8 GRIA2 [1] Spinocerebellar ataxia D00537 Topiramate [6] 6, 97, 140, 144, 156, 193
9 GRIA2 [1] Spinocerebellar ataxia D00775 Riluzole [9] 2, 3, 5, 8, 13, 17, 18, 203, 206
10 GRIA2 [1] Spinocerebellar ataxia D02696 Talampanel [2] 2, 6
11 GRIA2 [1] Spinocerebellar ataxia D08964 Perampanel [3] 2, 6, 144
12 GRIA3 [2] Spinocerebellar ataxia, Transcriptional misregulation in cancer D00537 Topiramate [6] 6, 97, 140, 144, 156, 193
13 GRIA3 [2] Spinocerebellar ataxia, Transcriptional misregulation in cancer D00775 Riluzole [9] 2, 3, 5, 8, 13, 17, 18, 203, 206
14 GRIA3 [2] Spinocerebellar ataxia, Transcriptional misregulation in cancer D02696 Talampanel [2] 2, 6
15 GRIA3 [2] Spinocerebellar ataxia, Transcriptional misregulation in cancer D08964 Perampanel [3] 2, 6, 144
16 GRIN1 [1] Spinocerebellar ataxia D00775 Riluzole [9] 2, 3, 5, 8, 13, 17, 18, 203, 206
17 GRIN1 [1] Spinocerebellar ataxia D03742 Dextromethorphan [11] 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156
18 GRIN1 [1] Spinocerebellar ataxia D07058 Acamprosate [2] 6, 206
19 GRIN1 [1] Spinocerebellar ataxia D07283 Esketamine [3] 2, 4, 70
20 GRIN1 [1] Spinocerebellar ataxia D07441 Amantadine [4] 6, 8, 13, 127
21 GRIN1 [1] Spinocerebellar ataxia D08098 Ketamine [8] 2, 4, 6, 13, 70, 113, 156, 215
22 GRIN1 [1] Spinocerebellar ataxia D08174 Memantine [8] 2, 6, 8, 13, 49, 127, 205, 206
23 GRIN1 [1] Spinocerebellar ataxia D09917 Latrepirdine [1] 8
24 GRIN2A [2] Spinocerebellar ataxia, Systemic lupus erythematosus D00775 Riluzole [9] 2, 3, 5, 8, 13, 17, 18, 203, 206
25 GRIN2A [2] Spinocerebellar ataxia, Systemic lupus erythematosus D03742 Dextromethorphan [11] 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156
26 GRIN2A [2] Spinocerebellar ataxia, Systemic lupus erythematosus D07058 Acamprosate [2] 6, 206
27 GRIN2A [2] Spinocerebellar ataxia, Systemic lupus erythematosus D07283 Esketamine [3] 2, 4, 70
28 GRIN2A [2] Spinocerebellar ataxia, Systemic lupus erythematosus D07441 Amantadine [4] 6, 8, 13, 127
29 GRIN2A [2] Spinocerebellar ataxia, Systemic lupus erythematosus D08098 Ketamine [8] 2, 4, 6, 13, 70, 113, 156, 215
30 GRIN2A [2] Spinocerebellar ataxia, Systemic lupus erythematosus D08174 Memantine [8] 2, 6, 8, 13, 49, 127, 205, 206
31 GRIN2A [2] Spinocerebellar ataxia, Systemic lupus erythematosus D09917 Latrepirdine [1] 8
32 GRIN2B [2] Spinocerebellar ataxia, Systemic lupus erythematosus D00775 Riluzole [9] 2, 3, 5, 8, 13, 17, 18, 203, 206
33 GRIN2B [2] Spinocerebellar ataxia, Systemic lupus erythematosus D03742 Dextromethorphan [11] 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156
34 GRIN2B [2] Spinocerebellar ataxia, Systemic lupus erythematosus D07058 Acamprosate [2] 6, 206
35 GRIN2B [2] Spinocerebellar ataxia, Systemic lupus erythematosus D07283 Esketamine [3] 2, 4, 70
36 GRIN2B [2] Spinocerebellar ataxia, Systemic lupus erythematosus D07441 Amantadine [4] 6, 8, 13, 127
37 GRIN2B [2] Spinocerebellar ataxia, Systemic lupus erythematosus D08098 Ketamine [8] 2, 4, 6, 13, 70, 113, 156, 215
38 GRIN2B [2] Spinocerebellar ataxia, Systemic lupus erythematosus D08174 Memantine [8] 2, 6, 8, 13, 49, 127, 205, 206
39 GRIN2B [2] Spinocerebellar ataxia, Systemic lupus erythematosus D09917 Latrepirdine [1] 8
40 GRIN2C [1] Spinocerebellar ataxia D00775 Riluzole [9] 2, 3, 5, 8, 13, 17, 18, 203, 206
41 GRIN2C [1] Spinocerebellar ataxia D03742 Dextromethorphan [11] 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156
42 GRIN2C [1] Spinocerebellar ataxia D07058 Acamprosate [2] 6, 206
43 GRIN2C [1] Spinocerebellar ataxia D07283 Esketamine [3] 2, 4, 70
44 GRIN2C [1] Spinocerebellar ataxia D07441 Amantadine [4] 6, 8, 13, 127
45 GRIN2C [1] Spinocerebellar ataxia D08098 Ketamine [8] 2, 4, 6, 13, 70, 113, 156, 215
46 GRIN2C [1] Spinocerebellar ataxia D08174 Memantine [8] 2, 6, 8, 13, 49, 127, 205, 206
47 GRIN2C [1] Spinocerebellar ataxia D09917 Latrepirdine [1] 8
48 GRIN2D [1] Spinocerebellar ataxia D00775 Riluzole [9] 2, 3, 5, 8, 13, 17, 18, 203, 206
49 GRIN2D [1] Spinocerebellar ataxia D03742 Dextromethorphan [11] 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156
50 GRIN2D [1] Spinocerebellar ataxia D07058 Acamprosate [2] 6, 206
51 GRIN2D [1] Spinocerebellar ataxia D07283 Esketamine [3] 2, 4, 70
52 GRIN2D [1] Spinocerebellar ataxia D07441 Amantadine [4] 6, 8, 13, 127
53 GRIN2D [1] Spinocerebellar ataxia D08098 Ketamine [8] 2, 4, 6, 13, 70, 113, 156, 215
54 GRIN2D [1] Spinocerebellar ataxia D08174 Memantine [8] 2, 6, 8, 13, 49, 127, 205, 206
55 GRIN2D [1] Spinocerebellar ataxia D09917 Latrepirdine [1] 8
56 KCNC3 [1] Spinocerebellar ataxia D04127 Dalfampridine [5] 3, 4, 6, 13, 14
57 KCNC3 [1] Spinocerebellar ataxia D10228 Amifampridine [3] 3, 11, 12
58 KCND3 [1] Spinocerebellar ataxia D02910 Amiodarone [2] 28, 127
59 KCND3 [1] Spinocerebellar ataxia D04127 Dalfampridine [5] 3, 4, 6, 13, 14
60 KCND3 [1] Spinocerebellar ataxia D10228 Amifampridine [3] 3, 11, 12
61 MAP3K5 [4] Tight junction, TNF signaling pathway, Thermogenesis, Spinocerebellar ataxia D10988 Selonsertib [1] 86
62 PIK3CA [9] VEGF signaling pathway, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Thyroid hormone signaling pathway, Type II diabetes mellitus, Spinocerebellar ataxia, Yersinia infection, Viral carcinogenesis D11011 Alpelisib [1] 138
63 PIK3CA [9] VEGF signaling pathway, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Thyroid hormone signaling pathway, Type II diabetes mellitus, Spinocerebellar ataxia, Yersinia infection, Viral carcinogenesis D11158 Leniolisib [2] 53, 65
64 PIK3CB [9] VEGF signaling pathway, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Thyroid hormone signaling pathway, Type II diabetes mellitus, Spinocerebellar ataxia, Yersinia infection, Viral carcinogenesis D11158 Leniolisib [2] 53, 65
65 PIK3CD [9] VEGF signaling pathway, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Thyroid hormone signaling pathway, Type II diabetes mellitus, Spinocerebellar ataxia, Yersinia infection, Viral carcinogenesis D11158 Leniolisib [2] 53, 65
66 PIK3CD [9] VEGF signaling pathway, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Thyroid hormone signaling pathway, Type II diabetes mellitus, Spinocerebellar ataxia, Yersinia infection, Viral carcinogenesis D11437 Parsaclisib [3] 35, 53, 61
67 PRKCB [6] Vascular smooth muscle contraction, Wnt signaling pathway, VEGF signaling pathway, Thyroid hormone synthesis, Thyroid hormone signaling pathway, Spinocerebellar ataxia D11935 Enzastaurin [1] 168
68 PSMB5 [1] Spinocerebellar ataxia D03150 Bortezomib [17] 11, 13, 26, 28, 46, 49, 51, 61, 63, 64, 66, 222, 228, 256, 283, 288, 331
69 PSMB5 [1] Spinocerebellar ataxia D08880 Carfilzomib [1] 28
70 PSMB5 [1] Spinocerebellar ataxia D10130 Ixazomib [5] 13, 16, 28, 51, 61