Target Gene/Pathway Pathway / Gene

  

Search results

No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank Disease ID
1 ADORA2A [1] Vascular smooth muscle contraction D00045 Adenosine [3] 13, 58, 65
2 ADORA2A [1] Vascular smooth muscle contraction D00528 Caffeine [8] 2, 6, 21, 46, 78, 96, 97, 265
3 ADORA2A [1] Vascular smooth muscle contraction D01453 Caffeine [8] 2, 6, 21, 46, 78, 96, 97, 265
4 ADORA2A [1] Vascular smooth muscle contraction D02769 Adenosine phosphate [1] 46
5 ADORA2A [1] Vascular smooth muscle contraction D04641 Istradefylline [1] 6
6 ADORA2A [1] Vascular smooth muscle contraction D05711 Regadenoson [1] 58
7 ADORA2A [1] Vascular smooth muscle contraction D09717 Preladenant [1] 6
8 ADORA2A [1] Vascular smooth muscle contraction D10174 Tozadenant [1] 6
9 ADORA2A [1] Vascular smooth muscle contraction D12568 Regadenoson [1] 58
10 ADORA2B [1] Vascular smooth muscle contraction D00045 Adenosine [3] 13, 58, 65
11 ADORA2B [1] Vascular smooth muscle contraction D00227 Aminophylline [1] 63
12 ADORA2B [1] Vascular smooth muscle contraction D00371 Theophylline [2] 236, 299
13 ADORA2B [1] Vascular smooth muscle contraction D02769 Adenosine phosphate [1] 46
14 ADORA2B [1] Vascular smooth muscle contraction D06103 Theophylline [2] 236, 299
15 ADRA1D [1] Vascular smooth muscle contraction D00076 Norepinephrine [2] 22, 296
16 ADRA1D [1] Vascular smooth muscle contraction D00095 Epinephrine [3] 46, 70, 96
17 ADRA1D [1] Vascular smooth muscle contraction D00124 Ephedrine [1] 11
18 ADRA1D [1] Vascular smooth muscle contraction D00255 Carvedilol [4] 57, 86, 113, 210
19 ADRA1D [1] Vascular smooth muscle contraction D00454 Olanzapine [2] 2, 8
20 ADRA1D [1] Vascular smooth muscle contraction D01277 Droxidopa [5] 5, 6, 17, 169, 170
21 ADRA1D [1] Vascular smooth muscle contraction D02349 Dipivefrin [1] 6
22 ADRA1D [1] Vascular smooth muscle contraction D02910 Amiodarone [2] 28, 127
23 ADRA1D [1] Vascular smooth muscle contraction D07874 Doxazosin [2] 57, 67
24 ADRA1D [1] Vascular smooth muscle contraction D08207 Methylergometrine [1] 280
25 ADRA1D [1] Vascular smooth muscle contraction D08220 Midodrine [3] 6, 17, 58
26 ADRA1D [1] Vascular smooth muscle contraction D08365 Phenylephrine [1] 22
27 ADRA1D [1] Vascular smooth muscle contraction D08449 Pseudoephedrine [1] 17
28 ADRA1D [1] Vascular smooth muscle contraction D08560 Tamsulosin [1] 13
29 ADRA1D [1] Vascular smooth muscle contraction D08569 Terazosin [1] 6
30 ADRA1B [1] Vascular smooth muscle contraction D00076 Norepinephrine [2] 22, 296
31 ADRA1B [1] Vascular smooth muscle contraction D00095 Epinephrine [3] 46, 70, 96
32 ADRA1B [1] Vascular smooth muscle contraction D00124 Ephedrine [1] 11
33 ADRA1B [1] Vascular smooth muscle contraction D00255 Carvedilol [4] 57, 86, 113, 210
34 ADRA1B [1] Vascular smooth muscle contraction D00454 Olanzapine [2] 2, 8
35 ADRA1B [1] Vascular smooth muscle contraction D01277 Droxidopa [5] 5, 6, 17, 169, 170
36 ADRA1B [1] Vascular smooth muscle contraction D02349 Dipivefrin [1] 6
37 ADRA1B [1] Vascular smooth muscle contraction D02910 Amiodarone [2] 28, 127
38 ADRA1B [1] Vascular smooth muscle contraction D07874 Doxazosin [2] 57, 67
39 ADRA1B [1] Vascular smooth muscle contraction D08207 Methylergometrine [1] 280
40 ADRA1B [1] Vascular smooth muscle contraction D08220 Midodrine [3] 6, 17, 58
41 ADRA1B [1] Vascular smooth muscle contraction D08365 Phenylephrine [1] 22
42 ADRA1B [1] Vascular smooth muscle contraction D08449 Pseudoephedrine [1] 17
43 ADRA1B [1] Vascular smooth muscle contraction D08560 Tamsulosin [1] 13
44 ADRA1B [1] Vascular smooth muscle contraction D08569 Terazosin [1] 6
45 ADRA1A [1] Vascular smooth muscle contraction D00076 Norepinephrine [2] 22, 296
46 ADRA1A [1] Vascular smooth muscle contraction D00095 Epinephrine [3] 46, 70, 96
47 ADRA1A [1] Vascular smooth muscle contraction D00124 Ephedrine [1] 11
48 ADRA1A [1] Vascular smooth muscle contraction D00255 Carvedilol [4] 57, 86, 113, 210
49 ADRA1A [1] Vascular smooth muscle contraction D00454 Olanzapine [2] 2, 8
50 ADRA1A [1] Vascular smooth muscle contraction D01277 Droxidopa [5] 5, 6, 17, 169, 170
51 ADRA1A [1] Vascular smooth muscle contraction D01965 Silodosin [2] 6, 13
52 ADRA1A [1] Vascular smooth muscle contraction D02349 Dipivefrin [1] 6
53 ADRA1A [1] Vascular smooth muscle contraction D02910 Amiodarone [2] 28, 127
54 ADRA1A [1] Vascular smooth muscle contraction D07124 Alfuzosin [1] 13
55 ADRA1A [1] Vascular smooth muscle contraction D07874 Doxazosin [2] 57, 67
56 ADRA1A [1] Vascular smooth muscle contraction D08207 Methylergometrine [1] 280
57 ADRA1A [1] Vascular smooth muscle contraction D08220 Midodrine [3] 6, 17, 58
58 ADRA1A [1] Vascular smooth muscle contraction D08365 Phenylephrine [1] 22
59 ADRA1A [1] Vascular smooth muscle contraction D08449 Pseudoephedrine [1] 17
60 ADRA1A [1] Vascular smooth muscle contraction D08560 Tamsulosin [1] 13
61 ADRA1A [1] Vascular smooth muscle contraction D08569 Terazosin [1] 6
62 AGTR1 [1] Vascular smooth muscle contraction D00150 Angiotensin II [7] 17, 19, 46, 66, 86, 222, 224
63 AGTR1 [1] Vascular smooth muscle contraction D00400 Valsartan [7] 57, 58, 66, 75, 218, 222, 224
64 AGTR1 [1] Vascular smooth muscle contraction D00522 Candesartan [2] 58, 67
65 AGTR1 [1] Vascular smooth muscle contraction D00523 Irbesartan [4] 66, 167, 168, 222
66 AGTR1 [1] Vascular smooth muscle contraction D00626 Candesartan cilexetil [1] 67
67 AGTR1 [1] Vascular smooth muscle contraction D00627 Telmisartan [2] 66, 67
68 AGTR1 [1] Vascular smooth muscle contraction D02014 Angiotensin II [7] 17, 19, 46, 66, 86, 222, 224
69 AGTR1 [1] Vascular smooth muscle contraction D08146 Losartan [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299
70 AGTR1 [1] Vascular smooth muscle contraction D11776 Sparsentan [3] 66, 218, 222
71 EDNRA [1] Vascular smooth muscle contraction D01227 Bosentan [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212
72 EDNRA [1] Vascular smooth muscle contraction D07077 Ambrisentan [7] 51, 84, 85, 86, 88, 210, 211
73 EDNRA [1] Vascular smooth muscle contraction D07171 Sitaxentan [1] 86
74 EDNRA [1] Vascular smooth muscle contraction D07538 Bosentan [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212
75 EDNRA [1] Vascular smooth muscle contraction D07741 Zibotentan [1] 51
76 EDNRA [1] Vascular smooth muscle contraction D10135 Macitentan [5] 51, 85, 86, 88, 210
77 EDNRA [1] Vascular smooth muscle contraction D11776 Sparsentan [3] 66, 218, 222
78 GUCY1A2 [1] Vascular smooth muscle contraction D00517 Amyl Nitrite [1] 58
79 GUCY1A2 [1] Vascular smooth muscle contraction D09572 Riociguat [6] 51, 84, 86, 88, 225, 299
80 GUCY1A1 [1] Vascular smooth muscle contraction D00517 Amyl Nitrite [1] 58
81 GUCY1A1 [1] Vascular smooth muscle contraction D09572 Riociguat [6] 51, 84, 86, 88, 225, 299
82 GUCY1B1 [1] Vascular smooth muscle contraction D00517 Amyl Nitrite [1] 58
83 GUCY1B1 [1] Vascular smooth muscle contraction D09572 Riociguat [6] 51, 84, 86, 88, 225, 299
84 NPR1 [1] Vascular smooth muscle contraction D04051 Erythrityl tetranitrate [1] 46
85 NPR1 [1] Vascular smooth muscle contraction D05147 Nesiritide [2] 46, 58
86 NPR2 [1] Vascular smooth muscle contraction D04051 Erythrityl tetranitrate [1] 46
87 NPR2 [1] Vascular smooth muscle contraction D11190 Vosoritide [1] 276
88 AVPR1A [1] Vascular smooth muscle contraction D00101 Vasopressin [1] 210
89 AVPR1A [1] Vascular smooth muscle contraction D06672 Terlipressin [1] 299
90 AVPR1A [1] Vascular smooth muscle contraction D07748 Conivaptan [1] 86
91 AVPR1B [1] Vascular smooth muscle contraction D00101 Vasopressin [1] 210
92 AVPR1B [1] Vascular smooth muscle contraction D06672 Terlipressin [1] 299
93 PRKCB [3] Vascular smooth muscle contraction, Wnt signaling pathway, VEGF signaling pathway D11935 Enzastaurin [1] 168
94 PRKCD [1] Vascular smooth muscle contraction D09671 Sotrastaurin [1] 97
95 PRKCE [1] Vascular smooth muscle contraction D09671 Sotrastaurin [1] 97
96 PRKCH [1] Vascular smooth muscle contraction D09671 Sotrastaurin [1] 97
97 PRKCQ [1] Vascular smooth muscle contraction D09671 Sotrastaurin [1] 97
98 MAP2K1 [3] Vascular smooth muscle contraction, VEGF signaling pathway, Yersinia infection D09666 Selumetinib [1] 34
99 MAP2K1 [3] Vascular smooth muscle contraction, VEGF signaling pathway, Yersinia infection D10175 Trametinib [4] 2, 34, 279, 280
100 MAP2K1 [3] Vascular smooth muscle contraction, VEGF signaling pathway, Yersinia infection D10405 Cobimetinib [1] 280
101 MAP2K1 [3] Vascular smooth muscle contraction, VEGF signaling pathway, Yersinia infection D10604 Binimetinib [1] 34
102 MAP2K1 [3] Vascular smooth muscle contraction, VEGF signaling pathway, Yersinia infection D11675 Mirdametinib [1] 34
103 MAP2K2 [3] Vascular smooth muscle contraction, VEGF signaling pathway, Yersinia infection D09666 Selumetinib [1] 34
104 MAP2K2 [3] Vascular smooth muscle contraction, VEGF signaling pathway, Yersinia infection D10175 Trametinib [4] 2, 34, 279, 280
105 MAP2K2 [3] Vascular smooth muscle contraction, VEGF signaling pathway, Yersinia infection D10405 Cobimetinib [1] 280
106 MAP2K2 [3] Vascular smooth muscle contraction, VEGF signaling pathway, Yersinia infection D10604 Binimetinib [1] 34
107 MAP2K2 [3] Vascular smooth muscle contraction, VEGF signaling pathway, Yersinia infection D11675 Mirdametinib [1] 34
108 PTGIR [1] Vascular smooth muscle contraction D00106 Epoprostenol [1] 86
109 PTGIR [1] Vascular smooth muscle contraction D01385 Ibudilast [2] 2, 13
110 PTGIR [1] Vascular smooth muscle contraction D02720 Beraprost [1] 86
111 PTGIR [1] Vascular smooth muscle contraction D02721 Iloprost [4] 51, 84, 85, 86
112 PTGIR [1] Vascular smooth muscle contraction D06213 Treprostinil [6] 51, 84, 85, 86, 88, 210
113 PTGIR [1] Vascular smooth muscle contraction D09994 Selexipag [5] 51, 70, 84, 86, 88
114 PTGIR [1] Vascular smooth muscle contraction D10725 Ralinepag [1] 86
115 RAF1 [2] Vascular smooth muscle contraction, VEGF signaling pathway D08524 Sorafenib [2] 34, 86
116 ROCK1 [2] Vascular smooth muscle contraction, Yersinia infection D07941 Fasudil [4] 2, 5, 7, 51
117 BRAF [1] Vascular smooth muscle contraction D08524 Sorafenib [2] 34, 86
118 BRAF [1] Vascular smooth muscle contraction D10064 Dabrafenib [1] 34
119 CACNA1C [1] Vascular smooth muscle contraction D00349 Isradipine [1] 6
120 CACNA1C [1] Vascular smooth muscle contraction D00437 Nifedipine [2] 50, 81
121 CACNA1C [1] Vascular smooth muscle contraction D00537 Topiramate [6] 6, 97, 140, 144, 156, 193
122 CACNA1C [1] Vascular smooth muscle contraction D01173 Cilnidipine [1] 67
123 CACNA1C [1] Vascular smooth muscle contraction D01908 Nilvadipine [1] 90
124 CACNA1C [1] Vascular smooth muscle contraction D02356 Verapamil [4] 58, 96, 140, 167
125 CACNA1C [1] Vascular smooth muscle contraction D07450 Amlodipine [4] 13, 51, 67, 298
126 CACNA1C [1] Vascular smooth muscle contraction D07845 Diltiazem [3] 51, 58, 86
127 CACNA1C [1] Vascular smooth muscle contraction D08270 Nicardipine [2] 70, 86
128 CACNA1C [1] Vascular smooth muscle contraction D08340 Perhexiline [2] 58, 272
129 CACNA1C [1] Vascular smooth muscle contraction D08441 Propiverine [1] 226
130 CACNA1D [1] Vascular smooth muscle contraction D00349 Isradipine [1] 6
131 CACNA1D [1] Vascular smooth muscle contraction D00437 Nifedipine [2] 50, 81
132 CACNA1D [1] Vascular smooth muscle contraction D00537 Topiramate [6] 6, 97, 140, 144, 156, 193
133 CACNA1D [1] Vascular smooth muscle contraction D01173 Cilnidipine [1] 67
134 CACNA1D [1] Vascular smooth muscle contraction D01908 Nilvadipine [1] 90
135 CACNA1D [1] Vascular smooth muscle contraction D02356 Verapamil [4] 58, 96, 140, 167
136 CACNA1D [1] Vascular smooth muscle contraction D07450 Amlodipine [4] 13, 51, 67, 298
137 CACNA1D [1] Vascular smooth muscle contraction D07845 Diltiazem [3] 51, 58, 86
138 CACNA1D [1] Vascular smooth muscle contraction D08270 Nicardipine [2] 70, 86
139 CACNA1D [1] Vascular smooth muscle contraction D08340 Perhexiline [2] 58, 272
140 CACNA1D [1] Vascular smooth muscle contraction D08441 Propiverine [1] 226
141 CACNA1F [1] Vascular smooth muscle contraction D00349 Isradipine [1] 6
142 CACNA1F [1] Vascular smooth muscle contraction D00437 Nifedipine [2] 50, 81
143 CACNA1F [1] Vascular smooth muscle contraction D00537 Topiramate [6] 6, 97, 140, 144, 156, 193
144 CACNA1F [1] Vascular smooth muscle contraction D01173 Cilnidipine [1] 67
145 CACNA1F [1] Vascular smooth muscle contraction D01908 Nilvadipine [1] 90
146 CACNA1F [1] Vascular smooth muscle contraction D02356 Verapamil [4] 58, 96, 140, 167
147 CACNA1F [1] Vascular smooth muscle contraction D07450 Amlodipine [4] 13, 51, 67, 298
148 CACNA1F [1] Vascular smooth muscle contraction D07845 Diltiazem [3] 51, 58, 86
149 CACNA1F [1] Vascular smooth muscle contraction D08270 Nicardipine [2] 70, 86
150 CACNA1F [1] Vascular smooth muscle contraction D08340 Perhexiline [2] 58, 272
151 CACNA1F [1] Vascular smooth muscle contraction D08441 Propiverine [1] 226
152 CACNA1S [1] Vascular smooth muscle contraction D00349 Isradipine [1] 6
153 CACNA1S [1] Vascular smooth muscle contraction D00437 Nifedipine [2] 50, 81
154 CACNA1S [1] Vascular smooth muscle contraction D00537 Topiramate [6] 6, 97, 140, 144, 156, 193
155 CACNA1S [1] Vascular smooth muscle contraction D01173 Cilnidipine [1] 67
156 CACNA1S [1] Vascular smooth muscle contraction D01908 Nilvadipine [1] 90
157 CACNA1S [1] Vascular smooth muscle contraction D02356 Verapamil [4] 58, 96, 140, 167
158 CACNA1S [1] Vascular smooth muscle contraction D07450 Amlodipine [4] 13, 51, 67, 298
159 CACNA1S [1] Vascular smooth muscle contraction D07845 Diltiazem [3] 51, 58, 86
160 CACNA1S [1] Vascular smooth muscle contraction D08270 Nicardipine [2] 70, 86
161 CACNA1S [1] Vascular smooth muscle contraction D08340 Perhexiline [2] 58, 272
162 CACNA1S [1] Vascular smooth muscle contraction D08441 Propiverine [1] 226
163 CALCA [1] Vascular smooth muscle contraction D11055 Fremanezumab [2] 124, 226
164 ROCK2 [3] Vascular smooth muscle contraction, Wnt signaling pathway, Yersinia infection D07941 Fasudil [4] 2, 5, 7, 51
165 ROCK2 [3] Vascular smooth muscle contraction, Wnt signaling pathway, Yersinia infection D11815 Belumosudil [2] 51, 85