Target Gene/Pathway Pathway / Gene

  

Search results

No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank Disease ID
1 ESR1 [1] Thyroid hormone signaling pathway D00105 Estradiol [7] 13, 46, 49, 65, 76, 226, 299
2 ESR1 [1] Thyroid hormone signaling pathway D00185 Estriol [2] 13, 227
3 ESR1 [1] Thyroid hormone signaling pathway D00289 Danazol [5] 60, 63, 64, 65, 285
4 ESR1 [1] Thyroid hormone signaling pathway D00554 Ethinylestradiol [4] 13, 46, 49, 299
5 ESR1 [1] Thyroid hormone signaling pathway D00575 Mestranol [2] 46, 49
6 ESR1 [1] Thyroid hormone signaling pathway D01161 Fulvestrant [2] 49, 86
7 ESR1 [1] Thyroid hormone signaling pathway D01413 Estradiol valerate [1] 65
8 ESR1 [1] Thyroid hormone signaling pathway D01986 Estriol [2] 13, 227
9 ESR1 [1] Thyroid hormone signaling pathway D02367 Desogestrel [1] 230
10 ESR1 [1] Thyroid hormone signaling pathway D07726 Clomifene [1] 74
11 ESR1 [1] Thyroid hormone signaling pathway D08409 Prasterone [6] 49, 53, 83, 86, 96, 113
12 ESR1 [1] Thyroid hormone signaling pathway D08465 Raloxifene [1] 46
13 ESR1 [1] Thyroid hormone signaling pathway D08559 Tamoxifen [3] 2, 113, 227
14 ESR1 [1] Thyroid hormone signaling pathway D11513 Estetrol [1] 53
15 ESR1 [1] Thyroid hormone signaling pathway D11514 Estetrol [1] 53
16 MTOR [2] Thyroid hormone signaling pathway, Type II diabetes mellitus D00753 Sirolimus [40] 2, 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331
17 MTOR [2] Thyroid hormone signaling pathway, Type II diabetes mellitus D02714 Everolimus [9] 34, 67, 89, 96, 137, 157, 158, 228, 277
18 MTOR [2] Thyroid hormone signaling pathway, Type II diabetes mellitus D06068 Temsirolimus [1] 13
19 HDAC1 [3] Thyroid hormone signaling pathway, Transcriptional misregulation in cancer, Viral carcinogenesis D06320 Vorinostat [2] 75, 96
20 HDAC2 [3] Thyroid hormone signaling pathway, Transcriptional misregulation in cancer, Viral carcinogenesis D06320 Vorinostat [2] 75, 96
21 MYH7 [2] Thyroid hormone signaling pathway, Viral myocarditis D12265 Mavacamten [1] 58
22 ATP1A1 [2] Thyroid hormone synthesis, Thyroid hormone signaling pathway D00297 Digitoxin [1] 299
23 ATP1A1 [2] Thyroid hormone synthesis, Thyroid hormone signaling pathway D00298 Digoxin [3] 8, 46, 210
24 ATP1A2 [2] Thyroid hormone synthesis, Thyroid hormone signaling pathway D00297 Digitoxin [1] 299
25 ATP1A2 [2] Thyroid hormone synthesis, Thyroid hormone signaling pathway D00298 Digoxin [3] 8, 46, 210
26 ATP1A3 [2] Thyroid hormone synthesis, Thyroid hormone signaling pathway D00297 Digitoxin [1] 299
27 ATP1A3 [2] Thyroid hormone synthesis, Thyroid hormone signaling pathway D00298 Digoxin [3] 8, 46, 210
28 ATP1A4 [2] Thyroid hormone synthesis, Thyroid hormone signaling pathway D00297 Digitoxin [1] 299
29 ATP1A4 [2] Thyroid hormone synthesis, Thyroid hormone signaling pathway D00298 Digoxin [3] 8, 46, 210
30 PIK3CA [7] VEGF signaling pathway, Toll-like receptor signaling pathway, TNF signaling pathway, Thyroid hormone signaling pathway, Type II diabetes mellitus, Yersinia infection, Viral carcinogenesis D11011 Alpelisib [1] 138
31 PIK3CA [7] VEGF signaling pathway, Toll-like receptor signaling pathway, TNF signaling pathway, Thyroid hormone signaling pathway, Type II diabetes mellitus, Yersinia infection, Viral carcinogenesis D11158 Leniolisib [2] 53, 65
32 PIK3CB [7] VEGF signaling pathway, Toll-like receptor signaling pathway, TNF signaling pathway, Thyroid hormone signaling pathway, Type II diabetes mellitus, Yersinia infection, Viral carcinogenesis D11158 Leniolisib [2] 53, 65
33 PIK3CD [7] VEGF signaling pathway, Toll-like receptor signaling pathway, TNF signaling pathway, Thyroid hormone signaling pathway, Type II diabetes mellitus, Yersinia infection, Viral carcinogenesis D11158 Leniolisib [2] 53, 65
34 PIK3CD [7] VEGF signaling pathway, Toll-like receptor signaling pathway, TNF signaling pathway, Thyroid hormone signaling pathway, Type II diabetes mellitus, Yersinia infection, Viral carcinogenesis D11437 Parsaclisib [3] 35, 53, 61
35 PRKCB [5] Vascular smooth muscle contraction, Wnt signaling pathway, VEGF signaling pathway, Thyroid hormone synthesis, Thyroid hormone signaling pathway D11935 Enzastaurin [1] 168
36 MAP2K1 [6] Vascular smooth muscle contraction, VEGF signaling pathway, Toll-like receptor signaling pathway, TNF signaling pathway, Thyroid hormone signaling pathway, Yersinia infection D09666 Selumetinib [1] 34
37 MAP2K1 [6] Vascular smooth muscle contraction, VEGF signaling pathway, Toll-like receptor signaling pathway, TNF signaling pathway, Thyroid hormone signaling pathway, Yersinia infection D10175 Trametinib [4] 2, 34, 279, 280
38 MAP2K1 [6] Vascular smooth muscle contraction, VEGF signaling pathway, Toll-like receptor signaling pathway, TNF signaling pathway, Thyroid hormone signaling pathway, Yersinia infection D10405 Cobimetinib [1] 280
39 MAP2K1 [6] Vascular smooth muscle contraction, VEGF signaling pathway, Toll-like receptor signaling pathway, TNF signaling pathway, Thyroid hormone signaling pathway, Yersinia infection D10604 Binimetinib [1] 34
40 MAP2K1 [6] Vascular smooth muscle contraction, VEGF signaling pathway, Toll-like receptor signaling pathway, TNF signaling pathway, Thyroid hormone signaling pathway, Yersinia infection D11675 Mirdametinib [1] 34
41 MAP2K2 [5] Vascular smooth muscle contraction, VEGF signaling pathway, Toll-like receptor signaling pathway, Thyroid hormone signaling pathway, Yersinia infection D09666 Selumetinib [1] 34
42 MAP2K2 [5] Vascular smooth muscle contraction, VEGF signaling pathway, Toll-like receptor signaling pathway, Thyroid hormone signaling pathway, Yersinia infection D10175 Trametinib [4] 2, 34, 279, 280
43 MAP2K2 [5] Vascular smooth muscle contraction, VEGF signaling pathway, Toll-like receptor signaling pathway, Thyroid hormone signaling pathway, Yersinia infection D10405 Cobimetinib [1] 280
44 MAP2K2 [5] Vascular smooth muscle contraction, VEGF signaling pathway, Toll-like receptor signaling pathway, Thyroid hormone signaling pathway, Yersinia infection D10604 Binimetinib [1] 34
45 MAP2K2 [5] Vascular smooth muscle contraction, VEGF signaling pathway, Toll-like receptor signaling pathway, Thyroid hormone signaling pathway, Yersinia infection D11675 Mirdametinib [1] 34
46 RAF1 [4] Vascular smooth muscle contraction, VEGF signaling pathway, Thyroid hormone signaling pathway, Tuberculosis D08524 Sorafenib [2] 34, 86
47 RXRA [2] Thyroid hormone signaling pathway, Transcriptional misregulation in cancer D02754 Acitretin [1] 37
48 RXRA [2] Thyroid hormone signaling pathway, Transcriptional misregulation in cancer D02815 Alitretinoin [1] 49
49 RXRA [2] Thyroid hormone signaling pathway, Transcriptional misregulation in cancer D03106 Bexarotene [2] 13, 75
50 RXRB [2] Thyroid hormone signaling pathway, Transcriptional misregulation in cancer D02754 Acitretin [1] 37
51 RXRB [2] Thyroid hormone signaling pathway, Transcriptional misregulation in cancer D02815 Alitretinoin [1] 49
52 RXRB [2] Thyroid hormone signaling pathway, Transcriptional misregulation in cancer D03106 Bexarotene [2] 13, 75
53 RXRG [2] Thyroid hormone signaling pathway, Transcriptional misregulation in cancer D02754 Acitretin [1] 37
54 RXRG [2] Thyroid hormone signaling pathway, Transcriptional misregulation in cancer D02815 Alitretinoin [1] 49
55 RXRG [2] Thyroid hormone signaling pathway, Transcriptional misregulation in cancer D03106 Bexarotene [2] 13, 75
56 SRC [6] VEGF signaling pathway, Tight junction, Thyroid hormone signaling pathway, Yersinia infection, Tuberculosis, Viral carcinogenesis D03252 Bosutinib [2] 2, 67
57 SRC [6] VEGF signaling pathway, Tight junction, Thyroid hormone signaling pathway, Yersinia infection, Tuberculosis, Viral carcinogenesis D03658 Dasatinib [2] 51, 85
58 SRC [6] VEGF signaling pathway, Tight junction, Thyroid hormone signaling pathway, Yersinia infection, Tuberculosis, Viral carcinogenesis D06414 Dasatinib [2] 51, 85
59 SRC [6] VEGF signaling pathway, Tight junction, Thyroid hormone signaling pathway, Yersinia infection, Tuberculosis, Viral carcinogenesis D09664 Saracatinib [3] 6, 89, 272
60 THRA [1] Thyroid hormone signaling pathway D07214 Tiratricol [2] 78, 139
61 THRA [1] Thyroid hormone signaling pathway D08125 Levothyroxine [5] 19, 49, 78, 80, 222
62 THRA [1] Thyroid hormone signaling pathway D08128 Liothyronine [4] 13, 78, 210, 212
63 THRB [1] Thyroid hormone signaling pathway D07214 Tiratricol [2] 78, 139
64 THRB [1] Thyroid hormone signaling pathway D08125 Levothyroxine [5] 19, 49, 78, 80, 222
65 THRB [1] Thyroid hormone signaling pathway D08128 Liothyronine [4] 13, 78, 210, 212
66 THRB [1] Thyroid hormone signaling pathway D09381 Sobetirome [1] 20
67 CASP9 [5] VEGF signaling pathway, Thyroid hormone signaling pathway, Toxoplasmosis, Tuberculosis, Viral myocarditis D11195 Rimiducid [6] 19, 60, 65, 284, 285, 326
68 HDAC3 [2] Thyroid hormone signaling pathway, Viral carcinogenesis D06320 Vorinostat [2] 75, 96