Target Gene/Pathway Pathway / Gene

  

Search results

No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank Disease ID
1 EGFR [14] Ras signaling pathway, Rap1 signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Regulation of actin cytoskeleton, Oxytocin signaling pathway, Relaxin signaling pathway, Parathyroid hormone synthesis, secretion and action, Shigellosis, Pathways in cancer, Proteoglycans in cancer, Pancreatic cancer, Prostate cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer D01977 Gefitinib [1] 75
2 EGFR [14] Ras signaling pathway, Rap1 signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Regulation of actin cytoskeleton, Oxytocin signaling pathway, Relaxin signaling pathway, Parathyroid hormone synthesis, secretion and action, Shigellosis, Pathways in cancer, Proteoglycans in cancer, Pancreatic cancer, Prostate cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer D03455 Cetuximab [2] 51, 86
3 EGFR [14] Ras signaling pathway, Rap1 signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Regulation of actin cytoskeleton, Oxytocin signaling pathway, Relaxin signaling pathway, Parathyroid hormone synthesis, secretion and action, Shigellosis, Pathways in cancer, Proteoglycans in cancer, Pancreatic cancer, Prostate cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer D07907 Erlotinib [1] 94
4 EGFR [14] Ras signaling pathway, Rap1 signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Regulation of actin cytoskeleton, Oxytocin signaling pathway, Relaxin signaling pathway, Parathyroid hormone synthesis, secretion and action, Shigellosis, Pathways in cancer, Proteoglycans in cancer, Pancreatic cancer, Prostate cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer D08108 Lapatinib [3] 34, 74, 75
5 EGFR [14] Ras signaling pathway, Rap1 signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Regulation of actin cytoskeleton, Oxytocin signaling pathway, Relaxin signaling pathway, Parathyroid hormone synthesis, secretion and action, Shigellosis, Pathways in cancer, Proteoglycans in cancer, Pancreatic cancer, Prostate cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer D08950 Neratinib [1] 34
6 EGFR [14] Ras signaling pathway, Rap1 signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Regulation of actin cytoskeleton, Oxytocin signaling pathway, Relaxin signaling pathway, Parathyroid hormone synthesis, secretion and action, Shigellosis, Pathways in cancer, Proteoglycans in cancer, Pancreatic cancer, Prostate cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer D11251 Icotinib [1] 34
7 EGFR [14] Ras signaling pathway, Rap1 signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Regulation of actin cytoskeleton, Oxytocin signaling pathway, Relaxin signaling pathway, Parathyroid hormone synthesis, secretion and action, Shigellosis, Pathways in cancer, Proteoglycans in cancer, Pancreatic cancer, Prostate cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer D11772 Tesevatinib [1] 67
8 GUCY1A2 [6] Purine metabolism, Vascular smooth muscle contraction, Platelet activation, Oxytocin signaling pathway, Renin secretion, Salivary secretion D00517 Amyl Nitrite [1] 58
9 GUCY1A2 [6] Purine metabolism, Vascular smooth muscle contraction, Platelet activation, Oxytocin signaling pathway, Renin secretion, Salivary secretion D09572 Riociguat [6] 51, 84, 86, 88, 225, 299
10 GUCY1A1 [6] Purine metabolism, Vascular smooth muscle contraction, Platelet activation, Oxytocin signaling pathway, Renin secretion, Salivary secretion D00517 Amyl Nitrite [1] 58
11 GUCY1A1 [6] Purine metabolism, Vascular smooth muscle contraction, Platelet activation, Oxytocin signaling pathway, Renin secretion, Salivary secretion D09572 Riociguat [6] 51, 84, 86, 88, 225, 299
12 GUCY1B1 [6] Purine metabolism, Vascular smooth muscle contraction, Platelet activation, Oxytocin signaling pathway, Renin secretion, Salivary secretion D00517 Amyl Nitrite [1] 58
13 GUCY1B1 [6] Purine metabolism, Vascular smooth muscle contraction, Platelet activation, Oxytocin signaling pathway, Renin secretion, Salivary secretion D09572 Riociguat [6] 51, 84, 86, 88, 225, 299
14 KCNJ3 [3] Retrograde endocannabinoid signaling, Serotonergic synapse, Oxytocin signaling pathway D02910 Amiodarone [2] 28, 127
15 KCNJ5 [3] Retrograde endocannabinoid signaling, Serotonergic synapse, Oxytocin signaling pathway D02910 Amiodarone [2] 28, 127
16 KCNJ12 [1] Oxytocin signaling pathway D02910 Amiodarone [2] 28, 127
17 NPR1 [6] Purine metabolism, Vascular smooth muscle contraction, Thermogenesis, Oxytocin signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion D04051 Erythrityl tetranitrate [1] 46
18 NPR1 [6] Purine metabolism, Vascular smooth muscle contraction, Thermogenesis, Oxytocin signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion D05147 Nesiritide [2] 46, 58
19 NPR2 [3] Purine metabolism, Vascular smooth muscle contraction, Oxytocin signaling pathway D04051 Erythrityl tetranitrate [1] 46
20 NPR2 [3] Purine metabolism, Vascular smooth muscle contraction, Oxytocin signaling pathway D11190 Vosoritide [1] 276
21 OXTR [1] Oxytocin signaling pathway D00089 Oxytocin [7] 6, 72, 127, 168, 193, 206, 226
22 OXTR [1] Oxytocin signaling pathway D03008 Atosiban [1] 118
23 PPP3CA [11] Wnt signaling pathway, VEGF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Oxytocin signaling pathway, Renin secretion, Prion disease, Pathways of neurodegeneration - multiple diseases, Tuberculosis, PD-L1 expression and PD-1 checkpoint pathway in cancer D00107 Tacrolimus [34] 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299
24 PPP3CA [11] Wnt signaling pathway, VEGF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Oxytocin signaling pathway, Renin secretion, Prion disease, Pathways of neurodegeneration - multiple diseases, Tuberculosis, PD-L1 expression and PD-1 checkpoint pathway in cancer D00184 Cyclosporine [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326
25 PPP3CA [11] Wnt signaling pathway, VEGF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Oxytocin signaling pathway, Renin secretion, Prion disease, Pathways of neurodegeneration - multiple diseases, Tuberculosis, PD-L1 expression and PD-1 checkpoint pathway in cancer D05480 Pimecrolimus [1] 160
26 PPP3CA [11] Wnt signaling pathway, VEGF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Oxytocin signaling pathway, Renin secretion, Prion disease, Pathways of neurodegeneration - multiple diseases, Tuberculosis, PD-L1 expression and PD-1 checkpoint pathway in cancer D08556 Tacrolimus [34] 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299
27 PPP3CA [11] Wnt signaling pathway, VEGF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Oxytocin signaling pathway, Renin secretion, Prion disease, Pathways of neurodegeneration - multiple diseases, Tuberculosis, PD-L1 expression and PD-1 checkpoint pathway in cancer D09033 Voclosporin [2] 49, 222
28 PPP3CB [11] Wnt signaling pathway, VEGF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Oxytocin signaling pathway, Renin secretion, Prion disease, Pathways of neurodegeneration - multiple diseases, Tuberculosis, PD-L1 expression and PD-1 checkpoint pathway in cancer D00107 Tacrolimus [34] 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299
29 PPP3CB [11] Wnt signaling pathway, VEGF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Oxytocin signaling pathway, Renin secretion, Prion disease, Pathways of neurodegeneration - multiple diseases, Tuberculosis, PD-L1 expression and PD-1 checkpoint pathway in cancer D00184 Cyclosporine [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326
30 PPP3CB [11] Wnt signaling pathway, VEGF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Oxytocin signaling pathway, Renin secretion, Prion disease, Pathways of neurodegeneration - multiple diseases, Tuberculosis, PD-L1 expression and PD-1 checkpoint pathway in cancer D05480 Pimecrolimus [1] 160
31 PPP3CB [11] Wnt signaling pathway, VEGF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Oxytocin signaling pathway, Renin secretion, Prion disease, Pathways of neurodegeneration - multiple diseases, Tuberculosis, PD-L1 expression and PD-1 checkpoint pathway in cancer D08556 Tacrolimus [34] 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299
32 PPP3CB [11] Wnt signaling pathway, VEGF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Oxytocin signaling pathway, Renin secretion, Prion disease, Pathways of neurodegeneration - multiple diseases, Tuberculosis, PD-L1 expression and PD-1 checkpoint pathway in cancer D09033 Voclosporin [2] 49, 222
33 PPP3CC [11] Wnt signaling pathway, VEGF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Oxytocin signaling pathway, Renin secretion, Prion disease, Pathways of neurodegeneration - multiple diseases, Tuberculosis, PD-L1 expression and PD-1 checkpoint pathway in cancer D00107 Tacrolimus [34] 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299
34 PPP3CC [11] Wnt signaling pathway, VEGF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Oxytocin signaling pathway, Renin secretion, Prion disease, Pathways of neurodegeneration - multiple diseases, Tuberculosis, PD-L1 expression and PD-1 checkpoint pathway in cancer D00184 Cyclosporine [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326
35 PPP3CC [11] Wnt signaling pathway, VEGF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Oxytocin signaling pathway, Renin secretion, Prion disease, Pathways of neurodegeneration - multiple diseases, Tuberculosis, PD-L1 expression and PD-1 checkpoint pathway in cancer D05480 Pimecrolimus [1] 160
36 PPP3CC [11] Wnt signaling pathway, VEGF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Oxytocin signaling pathway, Renin secretion, Prion disease, Pathways of neurodegeneration - multiple diseases, Tuberculosis, PD-L1 expression and PD-1 checkpoint pathway in cancer D08556 Tacrolimus [34] 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299
37 PPP3CC [11] Wnt signaling pathway, VEGF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Oxytocin signaling pathway, Renin secretion, Prion disease, Pathways of neurodegeneration - multiple diseases, Tuberculosis, PD-L1 expression and PD-1 checkpoint pathway in cancer D09033 Voclosporin [2] 49, 222
38 PPP3R1 [11] Wnt signaling pathway, VEGF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Oxytocin signaling pathway, Renin secretion, Prion disease, Pathways of neurodegeneration - multiple diseases, Tuberculosis, PD-L1 expression and PD-1 checkpoint pathway in cancer D00107 Tacrolimus [34] 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299
39 PPP3R1 [11] Wnt signaling pathway, VEGF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Oxytocin signaling pathway, Renin secretion, Prion disease, Pathways of neurodegeneration - multiple diseases, Tuberculosis, PD-L1 expression and PD-1 checkpoint pathway in cancer D00184 Cyclosporine [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326
40 PPP3R1 [11] Wnt signaling pathway, VEGF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Oxytocin signaling pathway, Renin secretion, Prion disease, Pathways of neurodegeneration - multiple diseases, Tuberculosis, PD-L1 expression and PD-1 checkpoint pathway in cancer D05480 Pimecrolimus [1] 160
41 PPP3R1 [11] Wnt signaling pathway, VEGF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Oxytocin signaling pathway, Renin secretion, Prion disease, Pathways of neurodegeneration - multiple diseases, Tuberculosis, PD-L1 expression and PD-1 checkpoint pathway in cancer D08556 Tacrolimus [34] 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299
42 PPP3R1 [11] Wnt signaling pathway, VEGF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Oxytocin signaling pathway, Renin secretion, Prion disease, Pathways of neurodegeneration - multiple diseases, Tuberculosis, PD-L1 expression and PD-1 checkpoint pathway in cancer D09033 Voclosporin [2] 49, 222
43 PPP3R2 [11] Wnt signaling pathway, VEGF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Oxytocin signaling pathway, Renin secretion, Prion disease, Pathways of neurodegeneration - multiple diseases, Tuberculosis, PD-L1 expression and PD-1 checkpoint pathway in cancer D00107 Tacrolimus [34] 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299
44 PPP3R2 [11] Wnt signaling pathway, VEGF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Oxytocin signaling pathway, Renin secretion, Prion disease, Pathways of neurodegeneration - multiple diseases, Tuberculosis, PD-L1 expression and PD-1 checkpoint pathway in cancer D00184 Cyclosporine [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326
45 PPP3R2 [11] Wnt signaling pathway, VEGF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Oxytocin signaling pathway, Renin secretion, Prion disease, Pathways of neurodegeneration - multiple diseases, Tuberculosis, PD-L1 expression and PD-1 checkpoint pathway in cancer D05480 Pimecrolimus [1] 160
46 PPP3R2 [11] Wnt signaling pathway, VEGF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Oxytocin signaling pathway, Renin secretion, Prion disease, Pathways of neurodegeneration - multiple diseases, Tuberculosis, PD-L1 expression and PD-1 checkpoint pathway in cancer D08556 Tacrolimus [34] 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299
47 PPP3R2 [11] Wnt signaling pathway, VEGF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Oxytocin signaling pathway, Renin secretion, Prion disease, Pathways of neurodegeneration - multiple diseases, Tuberculosis, PD-L1 expression and PD-1 checkpoint pathway in cancer D09033 Voclosporin [2] 49, 222
48 PRKAA1 [4] PI3K-Akt signaling pathway, Tight junction, Thermogenesis, Oxytocin signaling pathway D04966 Metformin [25] 2, 6, 8, 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301
49 PRKAA2 [4] PI3K-Akt signaling pathway, Tight junction, Thermogenesis, Oxytocin signaling pathway D04966 Metformin [25] 2, 6, 8, 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301
50 CACNA2D3 [1] Oxytocin signaling pathway D00332 Gabapentin [5] 6, 13, 19, 70, 298
51 CACNA2D3 [1] Oxytocin signaling pathway D02716 Pregabalin [5] 13, 36, 46, 70, 298
52 PRKCB [19] Ras signaling pathway, Rap1 signaling pathway, Phosphatidylinositol signaling system, Sphingolipid signaling pathway, Vascular smooth muscle contraction, Wnt signaling pathway, VEGF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Thyroid hormone synthesis, Thyroid hormone signaling pathway, Oxytocin signaling pathway, Parathyroid hormone synthesis, secretion and action, Salivary secretion, Pancreatic secretion, Spinocerebellar ataxia, Pathways of neurodegeneration - multiple diseases, Pathways in cancer, Proteoglycans in cancer D11935 Enzastaurin [1] 168
53 MAP2K1 [29] Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Serotonergic synapse, Regulation of actin cytoskeleton, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Thyroid hormone signaling pathway, Oxytocin signaling pathway, Relaxin signaling pathway, Parathyroid hormone synthesis, secretion and action, Pathways of neurodegeneration - multiple diseases, Salmonella infection, Yersinia infection, Pathways in cancer, Proteoglycans in cancer, Renal cell carcinoma, Pancreatic cancer, Prostate cancer, Thyroid cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer D09666 Selumetinib [1] 34
54 MAP2K1 [29] Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Serotonergic synapse, Regulation of actin cytoskeleton, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Thyroid hormone signaling pathway, Oxytocin signaling pathway, Relaxin signaling pathway, Parathyroid hormone synthesis, secretion and action, Pathways of neurodegeneration - multiple diseases, Salmonella infection, Yersinia infection, Pathways in cancer, Proteoglycans in cancer, Renal cell carcinoma, Pancreatic cancer, Prostate cancer, Thyroid cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer D10175 Trametinib [4] 2, 34, 279, 280
55 MAP2K1 [29] Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Serotonergic synapse, Regulation of actin cytoskeleton, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Thyroid hormone signaling pathway, Oxytocin signaling pathway, Relaxin signaling pathway, Parathyroid hormone synthesis, secretion and action, Pathways of neurodegeneration - multiple diseases, Salmonella infection, Yersinia infection, Pathways in cancer, Proteoglycans in cancer, Renal cell carcinoma, Pancreatic cancer, Prostate cancer, Thyroid cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer D10405 Cobimetinib [1] 280
56 MAP2K1 [29] Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Serotonergic synapse, Regulation of actin cytoskeleton, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Thyroid hormone signaling pathway, Oxytocin signaling pathway, Relaxin signaling pathway, Parathyroid hormone synthesis, secretion and action, Pathways of neurodegeneration - multiple diseases, Salmonella infection, Yersinia infection, Pathways in cancer, Proteoglycans in cancer, Renal cell carcinoma, Pancreatic cancer, Prostate cancer, Thyroid cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer D10604 Binimetinib [1] 34
57 MAP2K1 [29] Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Serotonergic synapse, Regulation of actin cytoskeleton, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Thyroid hormone signaling pathway, Oxytocin signaling pathway, Relaxin signaling pathway, Parathyroid hormone synthesis, secretion and action, Pathways of neurodegeneration - multiple diseases, Salmonella infection, Yersinia infection, Pathways in cancer, Proteoglycans in cancer, Renal cell carcinoma, Pancreatic cancer, Prostate cancer, Thyroid cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer D11675 Mirdametinib [1] 34
58 MAP2K2 [24] Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, Regulation of actin cytoskeleton, Prolactin signaling pathway, Thyroid hormone signaling pathway, Oxytocin signaling pathway, Relaxin signaling pathway, Pathways of neurodegeneration - multiple diseases, Salmonella infection, Yersinia infection, Pathways in cancer, Proteoglycans in cancer, Renal cell carcinoma, Prostate cancer, Thyroid cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer D09666 Selumetinib [1] 34
59 MAP2K2 [24] Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, Regulation of actin cytoskeleton, Prolactin signaling pathway, Thyroid hormone signaling pathway, Oxytocin signaling pathway, Relaxin signaling pathway, Pathways of neurodegeneration - multiple diseases, Salmonella infection, Yersinia infection, Pathways in cancer, Proteoglycans in cancer, Renal cell carcinoma, Prostate cancer, Thyroid cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer D10175 Trametinib [4] 2, 34, 279, 280
60 MAP2K2 [24] Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, Regulation of actin cytoskeleton, Prolactin signaling pathway, Thyroid hormone signaling pathway, Oxytocin signaling pathway, Relaxin signaling pathway, Pathways of neurodegeneration - multiple diseases, Salmonella infection, Yersinia infection, Pathways in cancer, Proteoglycans in cancer, Renal cell carcinoma, Prostate cancer, Thyroid cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer D10405 Cobimetinib [1] 280
61 MAP2K2 [24] Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, Regulation of actin cytoskeleton, Prolactin signaling pathway, Thyroid hormone signaling pathway, Oxytocin signaling pathway, Relaxin signaling pathway, Pathways of neurodegeneration - multiple diseases, Salmonella infection, Yersinia infection, Pathways in cancer, Proteoglycans in cancer, Renal cell carcinoma, Prostate cancer, Thyroid cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer D10604 Binimetinib [1] 34
62 MAP2K2 [24] Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, Regulation of actin cytoskeleton, Prolactin signaling pathway, Thyroid hormone signaling pathway, Oxytocin signaling pathway, Relaxin signaling pathway, Pathways of neurodegeneration - multiple diseases, Salmonella infection, Yersinia infection, Pathways in cancer, Proteoglycans in cancer, Renal cell carcinoma, Prostate cancer, Thyroid cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer D11675 Mirdametinib [1] 34
63 PTGS2 [9] VEGF signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Oxytocin signaling pathway, Regulation of lipolysis in adipocytes, Pathways of neurodegeneration - multiple diseases, Pathways in cancer, Small cell lung cancer D00109 Acetylsalicylic acid [14] 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251
64 PTGS2 [9] VEGF signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Oxytocin signaling pathway, Regulation of lipolysis in adipocytes, Pathways of neurodegeneration - multiple diseases, Pathways in cancer, Small cell lung cancer D00118 Naproxen [4] 13, 46, 107, 271
65 PTGS2 [9] VEGF signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Oxytocin signaling pathway, Regulation of lipolysis in adipocytes, Pathways of neurodegeneration - multiple diseases, Pathways in cancer, Small cell lung cancer D00120 Sulindac [1] 206
66 PTGS2 [9] VEGF signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Oxytocin signaling pathway, Regulation of lipolysis in adipocytes, Pathways of neurodegeneration - multiple diseases, Pathways in cancer, Small cell lung cancer D00126 Ibuprofen [7] 13, 46, 65, 107, 113, 271, 299
67 PTGS2 [9] VEGF signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Oxytocin signaling pathway, Regulation of lipolysis in adipocytes, Pathways of neurodegeneration - multiple diseases, Pathways in cancer, Small cell lung cancer D00130 Diflunisal [1] 28
68 PTGS2 [9] VEGF signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Oxytocin signaling pathway, Regulation of lipolysis in adipocytes, Pathways of neurodegeneration - multiple diseases, Pathways in cancer, Small cell lung cancer D00132 Ketoprofen [1] 46
69 PTGS2 [9] VEGF signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Oxytocin signaling pathway, Regulation of lipolysis in adipocytes, Pathways of neurodegeneration - multiple diseases, Pathways in cancer, Small cell lung cancer D00141 Indomethacin [3] 225, 271, 298
70 PTGS2 [9] VEGF signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Oxytocin signaling pathway, Regulation of lipolysis in adipocytes, Pathways of neurodegeneration - multiple diseases, Pathways in cancer, Small cell lung cancer D00217 Acetaminophen [15] 3, 6, 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337
71 PTGS2 [9] VEGF signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Oxytocin signaling pathway, Regulation of lipolysis in adipocytes, Pathways of neurodegeneration - multiple diseases, Pathways in cancer, Small cell lung cancer D00315 Etodolac [1] 46
72 PTGS2 [9] VEGF signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Oxytocin signaling pathway, Regulation of lipolysis in adipocytes, Pathways of neurodegeneration - multiple diseases, Pathways in cancer, Small cell lung cancer D00330 Flurbiprofen [3] 13, 21, 46
73 PTGS2 [9] VEGF signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Oxytocin signaling pathway, Regulation of lipolysis in adipocytes, Pathways of neurodegeneration - multiple diseases, Pathways in cancer, Small cell lung cancer D00428 Salsalate [1] 5
74 PTGS2 [9] VEGF signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Oxytocin signaling pathway, Regulation of lipolysis in adipocytes, Pathways of neurodegeneration - multiple diseases, Pathways in cancer, Small cell lung cancer D00567 Celecoxib [10] 2, 3, 34, 46, 70, 89, 107, 161, 171, 271
75 PTGS2 [9] VEGF signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Oxytocin signaling pathway, Regulation of lipolysis in adipocytes, Pathways of neurodegeneration - multiple diseases, Pathways in cancer, Small cell lung cancer D00568 Rofecoxib [1] 46
76 PTGS2 [9] VEGF signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Oxytocin signaling pathway, Regulation of lipolysis in adipocytes, Pathways of neurodegeneration - multiple diseases, Pathways in cancer, Small cell lung cancer D00969 Meloxicam [4] 46, 49, 271, 296
77 PTGS2 [9] VEGF signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Oxytocin signaling pathway, Regulation of lipolysis in adipocytes, Pathways of neurodegeneration - multiple diseases, Pathways in cancer, Small cell lung cancer D01049 Nimesulide [1] 46
78 PTGS2 [9] VEGF signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Oxytocin signaling pathway, Regulation of lipolysis in adipocytes, Pathways of neurodegeneration - multiple diseases, Pathways in cancer, Small cell lung cancer D01183 Tolfenamic acid [1] 5
79 PTGS2 [9] VEGF signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Oxytocin signaling pathway, Regulation of lipolysis in adipocytes, Pathways of neurodegeneration - multiple diseases, Pathways in cancer, Small cell lung cancer D01545 Aceclofenac [1] 46
80 PTGS2 [9] VEGF signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Oxytocin signaling pathway, Regulation of lipolysis in adipocytes, Pathways of neurodegeneration - multiple diseases, Pathways in cancer, Small cell lung cancer D02709 Valdecoxib [1] 46
81 PTGS2 [9] VEGF signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Oxytocin signaling pathway, Regulation of lipolysis in adipocytes, Pathways of neurodegeneration - multiple diseases, Pathways in cancer, Small cell lung cancer D03710 Etoricoxib [2] 46, 271
82 PTGS2 [9] VEGF signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Oxytocin signaling pathway, Regulation of lipolysis in adipocytes, Pathways of neurodegeneration - multiple diseases, Pathways in cancer, Small cell lung cancer D03714 Lumiracoxib [1] 46
83 PTGS2 [9] VEGF signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Oxytocin signaling pathway, Regulation of lipolysis in adipocytes, Pathways of neurodegeneration - multiple diseases, Pathways in cancer, Small cell lung cancer D03716 Parecoxib [2] 46, 271
84 PTGS2 [9] VEGF signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Oxytocin signaling pathway, Regulation of lipolysis in adipocytes, Pathways of neurodegeneration - multiple diseases, Pathways in cancer, Small cell lung cancer D07816 Diclofenac [5] 13, 34, 46, 78, 271
85 PTGS2 [9] VEGF signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Oxytocin signaling pathway, Regulation of lipolysis in adipocytes, Pathways of neurodegeneration - multiple diseases, Pathways in cancer, Small cell lung cancer D08104 Ketorolac [2] 70, 226
86 PTGS2 [9] VEGF signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Oxytocin signaling pathway, Regulation of lipolysis in adipocytes, Pathways of neurodegeneration - multiple diseases, Pathways in cancer, Small cell lung cancer D08149 Loxoprofen [2] 46, 271
87 RAF1 [26] Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, T cell receptor signaling pathway, Serotonergic synapse, Regulation of actin cytoskeleton, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Thyroid hormone signaling pathway, Oxytocin signaling pathway, Relaxin signaling pathway, Parathyroid hormone synthesis, secretion and action, Pathways of neurodegeneration - multiple diseases, Salmonella infection, Tuberculosis, Pathways in cancer, Proteoglycans in cancer, Renal cell carcinoma, Pancreatic cancer, Prostate cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer D08524 Sorafenib [2] 34, 86
88 ROCK1 [12] Sphingolipid signaling pathway, Vascular smooth muscle contraction, TGF-beta signaling pathway, Tight junction, Platelet activation, Regulation of actin cytoskeleton, Oxytocin signaling pathway, Pathogenic Escherichia coli infection, Shigellosis, Yersinia infection, Pathways in cancer, Proteoglycans in cancer D07941 Fasudil [4] 2, 5, 7, 51
89 SRC [15] Rap1 signaling pathway, VEGF signaling pathway, Tight junction, Platelet activation, Regulation of actin cytoskeleton, Prolactin signaling pathway, Thyroid hormone signaling pathway, Oxytocin signaling pathway, Relaxin signaling pathway, Pathogenic Escherichia coli infection, Shigellosis, Yersinia infection, Tuberculosis, Viral carcinogenesis, Proteoglycans in cancer D03252 Bosutinib [2] 2, 67
90 SRC [15] Rap1 signaling pathway, VEGF signaling pathway, Tight junction, Platelet activation, Regulation of actin cytoskeleton, Prolactin signaling pathway, Thyroid hormone signaling pathway, Oxytocin signaling pathway, Relaxin signaling pathway, Pathogenic Escherichia coli infection, Shigellosis, Yersinia infection, Tuberculosis, Viral carcinogenesis, Proteoglycans in cancer D03658 Dasatinib [2] 51, 85
91 SRC [15] Rap1 signaling pathway, VEGF signaling pathway, Tight junction, Platelet activation, Regulation of actin cytoskeleton, Prolactin signaling pathway, Thyroid hormone signaling pathway, Oxytocin signaling pathway, Relaxin signaling pathway, Pathogenic Escherichia coli infection, Shigellosis, Yersinia infection, Tuberculosis, Viral carcinogenesis, Proteoglycans in cancer D06414 Dasatinib [2] 51, 85
92 SRC [15] Rap1 signaling pathway, VEGF signaling pathway, Tight junction, Platelet activation, Regulation of actin cytoskeleton, Prolactin signaling pathway, Thyroid hormone signaling pathway, Oxytocin signaling pathway, Relaxin signaling pathway, Pathogenic Escherichia coli infection, Shigellosis, Yersinia infection, Tuberculosis, Viral carcinogenesis, Proteoglycans in cancer D09664 Saracatinib [3] 6, 89, 272
93 CACNA1C [9] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Oxytocin signaling pathway, Renin secretion, Type II diabetes mellitus, Prion disease, Pathways of neurodegeneration - multiple diseases D00349 Isradipine [1] 6
94 CACNA1C [9] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Oxytocin signaling pathway, Renin secretion, Type II diabetes mellitus, Prion disease, Pathways of neurodegeneration - multiple diseases D00437 Nifedipine [2] 50, 81
95 CACNA1C [9] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Oxytocin signaling pathway, Renin secretion, Type II diabetes mellitus, Prion disease, Pathways of neurodegeneration - multiple diseases D00537 Topiramate [6] 6, 97, 140, 144, 156, 193
96 CACNA1C [9] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Oxytocin signaling pathway, Renin secretion, Type II diabetes mellitus, Prion disease, Pathways of neurodegeneration - multiple diseases D01173 Cilnidipine [1] 67
97 CACNA1C [9] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Oxytocin signaling pathway, Renin secretion, Type II diabetes mellitus, Prion disease, Pathways of neurodegeneration - multiple diseases D01908 Nilvadipine [1] 90
98 CACNA1C [9] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Oxytocin signaling pathway, Renin secretion, Type II diabetes mellitus, Prion disease, Pathways of neurodegeneration - multiple diseases D02356 Verapamil [4] 58, 96, 140, 167
99 CACNA1C [9] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Oxytocin signaling pathway, Renin secretion, Type II diabetes mellitus, Prion disease, Pathways of neurodegeneration - multiple diseases D07450 Amlodipine [4] 13, 51, 67, 298
100 CACNA1C [9] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Oxytocin signaling pathway, Renin secretion, Type II diabetes mellitus, Prion disease, Pathways of neurodegeneration - multiple diseases D07845 Diltiazem [3] 51, 58, 86
101 CACNA1C [9] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Oxytocin signaling pathway, Renin secretion, Type II diabetes mellitus, Prion disease, Pathways of neurodegeneration - multiple diseases D08270 Nicardipine [2] 70, 86
102 CACNA1C [9] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Oxytocin signaling pathway, Renin secretion, Type II diabetes mellitus, Prion disease, Pathways of neurodegeneration - multiple diseases D08340 Perhexiline [2] 58, 272
103 CACNA1C [9] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Oxytocin signaling pathway, Renin secretion, Type II diabetes mellitus, Prion disease, Pathways of neurodegeneration - multiple diseases D08441 Propiverine [1] 226
104 CACNA1D [9] Vascular smooth muscle contraction, Tight junction, Retrograde endocannabinoid signaling, Serotonergic synapse, Oxytocin signaling pathway, Renin secretion, Type II diabetes mellitus, Prion disease, Pathways of neurodegeneration - multiple diseases D00349 Isradipine [1] 6
105 CACNA1D [9] Vascular smooth muscle contraction, Tight junction, Retrograde endocannabinoid signaling, Serotonergic synapse, Oxytocin signaling pathway, Renin secretion, Type II diabetes mellitus, Prion disease, Pathways of neurodegeneration - multiple diseases D00437 Nifedipine [2] 50, 81
106 CACNA1D [9] Vascular smooth muscle contraction, Tight junction, Retrograde endocannabinoid signaling, Serotonergic synapse, Oxytocin signaling pathway, Renin secretion, Type II diabetes mellitus, Prion disease, Pathways of neurodegeneration - multiple diseases D00537 Topiramate [6] 6, 97, 140, 144, 156, 193
107 CACNA1D [9] Vascular smooth muscle contraction, Tight junction, Retrograde endocannabinoid signaling, Serotonergic synapse, Oxytocin signaling pathway, Renin secretion, Type II diabetes mellitus, Prion disease, Pathways of neurodegeneration - multiple diseases D01173 Cilnidipine [1] 67
108 CACNA1D [9] Vascular smooth muscle contraction, Tight junction, Retrograde endocannabinoid signaling, Serotonergic synapse, Oxytocin signaling pathway, Renin secretion, Type II diabetes mellitus, Prion disease, Pathways of neurodegeneration - multiple diseases D01908 Nilvadipine [1] 90
109 CACNA1D [9] Vascular smooth muscle contraction, Tight junction, Retrograde endocannabinoid signaling, Serotonergic synapse, Oxytocin signaling pathway, Renin secretion, Type II diabetes mellitus, Prion disease, Pathways of neurodegeneration - multiple diseases D02356 Verapamil [4] 58, 96, 140, 167
110 CACNA1D [9] Vascular smooth muscle contraction, Tight junction, Retrograde endocannabinoid signaling, Serotonergic synapse, Oxytocin signaling pathway, Renin secretion, Type II diabetes mellitus, Prion disease, Pathways of neurodegeneration - multiple diseases D07450 Amlodipine [4] 13, 51, 67, 298
111 CACNA1D [9] Vascular smooth muscle contraction, Tight junction, Retrograde endocannabinoid signaling, Serotonergic synapse, Oxytocin signaling pathway, Renin secretion, Type II diabetes mellitus, Prion disease, Pathways of neurodegeneration - multiple diseases D07845 Diltiazem [3] 51, 58, 86
112 CACNA1D [9] Vascular smooth muscle contraction, Tight junction, Retrograde endocannabinoid signaling, Serotonergic synapse, Oxytocin signaling pathway, Renin secretion, Type II diabetes mellitus, Prion disease, Pathways of neurodegeneration - multiple diseases D08270 Nicardipine [2] 70, 86
113 CACNA1D [9] Vascular smooth muscle contraction, Tight junction, Retrograde endocannabinoid signaling, Serotonergic synapse, Oxytocin signaling pathway, Renin secretion, Type II diabetes mellitus, Prion disease, Pathways of neurodegeneration - multiple diseases D08340 Perhexiline [2] 58, 272
114 CACNA1D [9] Vascular smooth muscle contraction, Tight junction, Retrograde endocannabinoid signaling, Serotonergic synapse, Oxytocin signaling pathway, Renin secretion, Type II diabetes mellitus, Prion disease, Pathways of neurodegeneration - multiple diseases D08441 Propiverine [1] 226
115 CACNA1F [7] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Oxytocin signaling pathway, Renin secretion, Prion disease, Pathways of neurodegeneration - multiple diseases D00349 Isradipine [1] 6
116 CACNA1F [7] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Oxytocin signaling pathway, Renin secretion, Prion disease, Pathways of neurodegeneration - multiple diseases D00437 Nifedipine [2] 50, 81
117 CACNA1F [7] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Oxytocin signaling pathway, Renin secretion, Prion disease, Pathways of neurodegeneration - multiple diseases D00537 Topiramate [6] 6, 97, 140, 144, 156, 193
118 CACNA1F [7] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Oxytocin signaling pathway, Renin secretion, Prion disease, Pathways of neurodegeneration - multiple diseases D01173 Cilnidipine [1] 67
119 CACNA1F [7] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Oxytocin signaling pathway, Renin secretion, Prion disease, Pathways of neurodegeneration - multiple diseases D01908 Nilvadipine [1] 90
120 CACNA1F [7] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Oxytocin signaling pathway, Renin secretion, Prion disease, Pathways of neurodegeneration - multiple diseases D02356 Verapamil [4] 58, 96, 140, 167
121 CACNA1F [7] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Oxytocin signaling pathway, Renin secretion, Prion disease, Pathways of neurodegeneration - multiple diseases D07450 Amlodipine [4] 13, 51, 67, 298
122 CACNA1F [7] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Oxytocin signaling pathway, Renin secretion, Prion disease, Pathways of neurodegeneration - multiple diseases D07845 Diltiazem [3] 51, 58, 86
123 CACNA1F [7] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Oxytocin signaling pathway, Renin secretion, Prion disease, Pathways of neurodegeneration - multiple diseases D08270 Nicardipine [2] 70, 86
124 CACNA1F [7] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Oxytocin signaling pathway, Renin secretion, Prion disease, Pathways of neurodegeneration - multiple diseases D08340 Perhexiline [2] 58, 272
125 CACNA1F [7] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Oxytocin signaling pathway, Renin secretion, Prion disease, Pathways of neurodegeneration - multiple diseases D08441 Propiverine [1] 226
126 CACNA1S [7] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Oxytocin signaling pathway, Renin secretion, Prion disease, Pathways of neurodegeneration - multiple diseases D00349 Isradipine [1] 6
127 CACNA1S [7] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Oxytocin signaling pathway, Renin secretion, Prion disease, Pathways of neurodegeneration - multiple diseases D00437 Nifedipine [2] 50, 81
128 CACNA1S [7] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Oxytocin signaling pathway, Renin secretion, Prion disease, Pathways of neurodegeneration - multiple diseases D00537 Topiramate [6] 6, 97, 140, 144, 156, 193
129 CACNA1S [7] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Oxytocin signaling pathway, Renin secretion, Prion disease, Pathways of neurodegeneration - multiple diseases D01173 Cilnidipine [1] 67
130 CACNA1S [7] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Oxytocin signaling pathway, Renin secretion, Prion disease, Pathways of neurodegeneration - multiple diseases D01908 Nilvadipine [1] 90
131 CACNA1S [7] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Oxytocin signaling pathway, Renin secretion, Prion disease, Pathways of neurodegeneration - multiple diseases D02356 Verapamil [4] 58, 96, 140, 167
132 CACNA1S [7] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Oxytocin signaling pathway, Renin secretion, Prion disease, Pathways of neurodegeneration - multiple diseases D07450 Amlodipine [4] 13, 51, 67, 298
133 CACNA1S [7] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Oxytocin signaling pathway, Renin secretion, Prion disease, Pathways of neurodegeneration - multiple diseases D07845 Diltiazem [3] 51, 58, 86
134 CACNA1S [7] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Oxytocin signaling pathway, Renin secretion, Prion disease, Pathways of neurodegeneration - multiple diseases D08270 Nicardipine [2] 70, 86
135 CACNA1S [7] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Oxytocin signaling pathway, Renin secretion, Prion disease, Pathways of neurodegeneration - multiple diseases D08340 Perhexiline [2] 58, 272
136 CACNA1S [7] Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Serotonergic synapse, Oxytocin signaling pathway, Renin secretion, Prion disease, Pathways of neurodegeneration - multiple diseases D08441 Propiverine [1] 226
137 CACNA2D1 [1] Oxytocin signaling pathway D00332 Gabapentin [5] 6, 13, 19, 70, 298
138 CACNA2D1 [1] Oxytocin signaling pathway D02716 Pregabalin [5] 13, 36, 46, 70, 298
139 CACNA2D1 [1] Oxytocin signaling pathway D11203 Mirogabalin [1] 70
140 CACNA2D2 [1] Oxytocin signaling pathway D00332 Gabapentin [5] 6, 13, 19, 70, 298
141 CACNA2D2 [1] Oxytocin signaling pathway D02716 Pregabalin [5] 13, 36, 46, 70, 298
142 CACNA2D2 [1] Oxytocin signaling pathway D11203 Mirogabalin [1] 70
143 CACNA2D4 [1] Oxytocin signaling pathway D00332 Gabapentin [5] 6, 13, 19, 70, 298
144 CACNA2D4 [1] Oxytocin signaling pathway D02716 Pregabalin [5] 13, 36, 46, 70, 298
145 ROCK2 [13] Sphingolipid signaling pathway, Vascular smooth muscle contraction, Wnt signaling pathway, Tight junction, Platelet activation, Regulation of actin cytoskeleton, Oxytocin signaling pathway, Pathogenic Escherichia coli infection, Shigellosis, Salmonella infection, Yersinia infection, Pathways in cancer, Proteoglycans in cancer D07941 Fasudil [4] 2, 5, 7, 51
146 ROCK2 [13] Sphingolipid signaling pathway, Vascular smooth muscle contraction, Wnt signaling pathway, Tight junction, Platelet activation, Regulation of actin cytoskeleton, Oxytocin signaling pathway, Pathogenic Escherichia coli infection, Shigellosis, Salmonella infection, Yersinia infection, Pathways in cancer, Proteoglycans in cancer D11815 Belumosudil [2] 51, 85
147 CD38 [3] Oxytocin signaling pathway, Salivary secretion, Pancreatic secretion D10777 Daratumumab [5] 13, 28, 48, 49, 63
148 CD38 [3] Oxytocin signaling pathway, Salivary secretion, Pancreatic secretion D11050 Isatuximab [3] 28, 61, 283
149 CD38 [3] Oxytocin signaling pathway, Salivary secretion, Pancreatic secretion D11945 Mezagitamab [2] 63, 66