Target Gene/Pathway Pathway / Gene

  

Search results

No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank Disease ID
1 MAPK14 [3] VEGF signaling pathway, Yersinia infection, Tuberculosis D09639 Losmapimod [2] 113, 222
2 MAPK14 [3] VEGF signaling pathway, Yersinia infection, Tuberculosis D10959 Neflamapimod [1] 8
3 IFNA1 [1] Tuberculosis D09662 Rontalizumab [1] 49
4 IFNA1 [1] Tuberculosis D09668 Sifalimumab [1] 49
5 IFNA2 [1] Tuberculosis D09662 Rontalizumab [1] 49
6 IFNA2 [1] Tuberculosis D09668 Sifalimumab [1] 49
7 IFNA4 [1] Tuberculosis D09662 Rontalizumab [1] 49
8 IFNA4 [1] Tuberculosis D09668 Sifalimumab [1] 49
9 IFNA5 [1] Tuberculosis D09662 Rontalizumab [1] 49
10 IFNA5 [1] Tuberculosis D09668 Sifalimumab [1] 49
11 IFNA6 [1] Tuberculosis D09662 Rontalizumab [1] 49
12 IFNA6 [1] Tuberculosis D09668 Sifalimumab [1] 49
13 IFNA7 [1] Tuberculosis D09662 Rontalizumab [1] 49
14 IFNA7 [1] Tuberculosis D09668 Sifalimumab [1] 49
15 IFNA8 [1] Tuberculosis D09662 Rontalizumab [1] 49
16 IFNA8 [1] Tuberculosis D09668 Sifalimumab [1] 49
17 IFNA10 [1] Tuberculosis D09662 Rontalizumab [1] 49
18 IFNA10 [1] Tuberculosis D09668 Sifalimumab [1] 49
19 IFNA13 [1] Tuberculosis D09662 Rontalizumab [1] 49
20 IFNA13 [1] Tuberculosis D09668 Sifalimumab [1] 49
21 IFNA14 [1] Tuberculosis D09662 Rontalizumab [1] 49
22 IFNA14 [1] Tuberculosis D09668 Sifalimumab [1] 49
23 IFNA16 [1] Tuberculosis D09662 Rontalizumab [1] 49
24 IFNA16 [1] Tuberculosis D09668 Sifalimumab [1] 49
25 IFNA17 [1] Tuberculosis D09662 Rontalizumab [1] 49
26 IFNA17 [1] Tuberculosis D09668 Sifalimumab [1] 49
27 IFNA21 [1] Tuberculosis D09662 Rontalizumab [1] 49
28 IFNA21 [1] Tuberculosis D09668 Sifalimumab [1] 49
29 IFNG [2] Type I diabetes mellitus, Tuberculosis D04242 Fontolizumab [1] 46
30 IFNG [2] Type I diabetes mellitus, Tuberculosis D11120 Emapalumab [3] 49, 65, 107
31 IFNGR1 [1] Tuberculosis D00747 Interferon gamma-1b [7] 18, 65, 85, 228, 299, 301, 326
32 IFNGR2 [1] Tuberculosis D00747 Interferon gamma-1b [7] 18, 65, 85, 228, 299, 301, 326
33 IL1A [2] Type I diabetes mellitus, Tuberculosis D01583 Pirfenidone [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228
34 IL1A [2] Type I diabetes mellitus, Tuberculosis D06635 Rilonacept [4] 51, 106, 107, 266
35 IL1A [2] Type I diabetes mellitus, Tuberculosis D11253 Bermekimab [1] 51
36 IL1B [3] Type I diabetes mellitus, Yersinia infection, Tuberculosis D01583 Pirfenidone [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228
37 IL1B [3] Type I diabetes mellitus, Yersinia infection, Tuberculosis D06635 Rilonacept [4] 51, 106, 107, 266
38 IL1B [3] Type I diabetes mellitus, Yersinia infection, Tuberculosis D09315 Canakinumab [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269
39 IL1B [3] Type I diabetes mellitus, Yersinia infection, Tuberculosis D09911 Gevokizumab [4] 41, 50, 56, 269
40 IL6 [3] Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, Tuberculosis D01583 Pirfenidone [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228
41 IL6 [3] Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, Tuberculosis D08976 Pomalidomide [5] 28, 51, 85, 227, 331
42 IL6 [3] Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, Tuberculosis D09669 Siltuximab [2] 28, 331
43 IL6 [3] Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, Tuberculosis D10080 Sirukumab [2] 41, 46
44 IL6 [3] Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, Tuberculosis D12487 Olokizumab [2] 46, 96
45 IL10 [3] Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, Tuberculosis D01583 Pirfenidone [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228
46 IL12A [2] Type I diabetes mellitus, Tuberculosis D09214 Ustekinumab [16] 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271
47 IL12B [2] Type I diabetes mellitus, Tuberculosis D09214 Ustekinumab [16] 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271
48 JAK1 [2] Tuberculosis, Viral carcinogenesis D09959 Ruxolitinib [3] 60, 65, 228
49 JAK1 [2] Tuberculosis, Viral carcinogenesis D09970 Tofacitinib [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300
50 JAK1 [2] Tuberculosis, Viral carcinogenesis D10308 Baricitinib [13] 2, 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325
51 JAK1 [2] Tuberculosis, Viral carcinogenesis D10653 Peficitinib [1] 46
52 JAK1 [2] Tuberculosis, Viral carcinogenesis D10871 Filgotinib [6] 46, 53, 96, 97, 222, 271
53 JAK1 [2] Tuberculosis, Viral carcinogenesis D10944 Itacitinib [4] 46, 51, 97, 228
54 JAK1 [2] Tuberculosis, Viral carcinogenesis D10994 Upadacitinib [8] 40, 41, 46, 49, 96, 97, 107, 271
55 JAK1 [2] Tuberculosis, Viral carcinogenesis D11400 Abrocitinib [1] 84
56 JAK2 [1] Tuberculosis D09959 Ruxolitinib [3] 60, 65, 228
57 JAK2 [1] Tuberculosis D09970 Tofacitinib [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300
58 JAK2 [1] Tuberculosis D10308 Baricitinib [13] 2, 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325
59 JAK2 [1] Tuberculosis D10653 Peficitinib [1] 46
60 NFKB1 [3] Yersinia infection, Tuberculosis, Viral carcinogenesis D01146 Iguratimod [5] 46, 51, 53, 271, 300
61 IL23A [1] Tuberculosis D09214 Ustekinumab [16] 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271
62 IL23A [1] Tuberculosis D10400 Tildrakizumab [2] 162, 271
63 IL23A [1] Tuberculosis D10438 Guselkumab [5] 37, 41, 51, 96, 97
64 IL23A [1] Tuberculosis D10912 Brazikumab [2] 96, 97
65 IL23A [1] Tuberculosis D11052 Risankizumab [4] 37, 96, 97, 271
66 IL23A [1] Tuberculosis D11123 Mirikizumab [3] 37, 96, 97
67 TLR9 [1] Tuberculosis D12275 Cobitolimod [1] 97
68 PPP3CA [3] Wnt signaling pathway, VEGF signaling pathway, Tuberculosis D00107 Tacrolimus [34] 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299
69 PPP3CA [3] Wnt signaling pathway, VEGF signaling pathway, Tuberculosis D00184 Cyclosporine [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326
70 PPP3CA [3] Wnt signaling pathway, VEGF signaling pathway, Tuberculosis D05480 Pimecrolimus [1] 160
71 PPP3CA [3] Wnt signaling pathway, VEGF signaling pathway, Tuberculosis D08556 Tacrolimus [34] 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299
72 PPP3CA [3] Wnt signaling pathway, VEGF signaling pathway, Tuberculosis D09033 Voclosporin [2] 49, 222
73 PPP3CB [3] Wnt signaling pathway, VEGF signaling pathway, Tuberculosis D00107 Tacrolimus [34] 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299
74 PPP3CB [3] Wnt signaling pathway, VEGF signaling pathway, Tuberculosis D00184 Cyclosporine [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326
75 PPP3CB [3] Wnt signaling pathway, VEGF signaling pathway, Tuberculosis D05480 Pimecrolimus [1] 160
76 PPP3CB [3] Wnt signaling pathway, VEGF signaling pathway, Tuberculosis D08556 Tacrolimus [34] 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299
77 PPP3CB [3] Wnt signaling pathway, VEGF signaling pathway, Tuberculosis D09033 Voclosporin [2] 49, 222
78 PPP3CC [3] Wnt signaling pathway, VEGF signaling pathway, Tuberculosis D00107 Tacrolimus [34] 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299
79 PPP3CC [3] Wnt signaling pathway, VEGF signaling pathway, Tuberculosis D00184 Cyclosporine [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326
80 PPP3CC [3] Wnt signaling pathway, VEGF signaling pathway, Tuberculosis D05480 Pimecrolimus [1] 160
81 PPP3CC [3] Wnt signaling pathway, VEGF signaling pathway, Tuberculosis D08556 Tacrolimus [34] 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299
82 PPP3CC [3] Wnt signaling pathway, VEGF signaling pathway, Tuberculosis D09033 Voclosporin [2] 49, 222
83 PPP3R1 [3] Wnt signaling pathway, VEGF signaling pathway, Tuberculosis D00107 Tacrolimus [34] 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299
84 PPP3R1 [3] Wnt signaling pathway, VEGF signaling pathway, Tuberculosis D00184 Cyclosporine [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326
85 PPP3R1 [3] Wnt signaling pathway, VEGF signaling pathway, Tuberculosis D05480 Pimecrolimus [1] 160
86 PPP3R1 [3] Wnt signaling pathway, VEGF signaling pathway, Tuberculosis D08556 Tacrolimus [34] 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299
87 PPP3R1 [3] Wnt signaling pathway, VEGF signaling pathway, Tuberculosis D09033 Voclosporin [2] 49, 222
88 PPP3R2 [3] Wnt signaling pathway, VEGF signaling pathway, Tuberculosis D00107 Tacrolimus [34] 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299
89 PPP3R2 [3] Wnt signaling pathway, VEGF signaling pathway, Tuberculosis D00184 Cyclosporine [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326
90 PPP3R2 [3] Wnt signaling pathway, VEGF signaling pathway, Tuberculosis D05480 Pimecrolimus [1] 160
91 PPP3R2 [3] Wnt signaling pathway, VEGF signaling pathway, Tuberculosis D08556 Tacrolimus [34] 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299
92 PPP3R2 [3] Wnt signaling pathway, VEGF signaling pathway, Tuberculosis D09033 Voclosporin [2] 49, 222
93 MAPK11 [3] VEGF signaling pathway, Yersinia infection, Tuberculosis D09639 Losmapimod [2] 113, 222
94 MAPK11 [3] VEGF signaling pathway, Yersinia infection, Tuberculosis D10959 Neflamapimod [1] 8
95 MAPK13 [3] VEGF signaling pathway, Yersinia infection, Tuberculosis D09639 Losmapimod [2] 113, 222
96 MAPK13 [3] VEGF signaling pathway, Yersinia infection, Tuberculosis D10959 Neflamapimod [1] 8
97 RAF1 [3] Vascular smooth muscle contraction, VEGF signaling pathway, Tuberculosis D08524 Sorafenib [2] 34, 86
98 BCL2 [1] Tuberculosis D10679 Venetoclax [1] 28
99 RELA [3] Yersinia infection, Tuberculosis, Viral carcinogenesis D12181 Edasalonexent [1] 113
100 MAPK12 [3] VEGF signaling pathway, Yersinia infection, Tuberculosis D09639 Losmapimod [2] 113, 222
101 MAPK12 [3] VEGF signaling pathway, Yersinia infection, Tuberculosis D10959 Neflamapimod [1] 8
102 SRC [4] VEGF signaling pathway, Yersinia infection, Tuberculosis, Viral carcinogenesis D03252 Bosutinib [2] 2, 67
103 SRC [4] VEGF signaling pathway, Yersinia infection, Tuberculosis, Viral carcinogenesis D03658 Dasatinib [2] 51, 85
104 SRC [4] VEGF signaling pathway, Yersinia infection, Tuberculosis, Viral carcinogenesis D06414 Dasatinib [2] 51, 85
105 SRC [4] VEGF signaling pathway, Yersinia infection, Tuberculosis, Viral carcinogenesis D09664 Saracatinib [3] 6, 89, 272
106 SYK [2] Tuberculosis, Viral carcinogenesis D09347 Fostamatinib [4] 46, 49, 61, 66
107 TGFB1 [1] Tuberculosis D09620 Fresolimumab [3] 51, 85, 222
108 TGFB2 [1] Tuberculosis D09620 Fresolimumab [3] 51, 85, 222
109 TGFB3 [1] Tuberculosis D09620 Fresolimumab [3] 51, 85, 222
110 TNF [5] Viral protein interaction with cytokine and cytokine receptor, Type II diabetes mellitus, Type I diabetes mellitus, Yersinia infection, Tuberculosis D00742 Etanercept [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285
111 TNF [5] Viral protein interaction with cytokine and cytokine receptor, Type II diabetes mellitus, Type I diabetes mellitus, Yersinia infection, Tuberculosis D00754 Thalidomide [20] 2, 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331
112 TNF [5] Viral protein interaction with cytokine and cytokine receptor, Type II diabetes mellitus, Type I diabetes mellitus, Yersinia infection, Tuberculosis D01583 Pirfenidone [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228
113 TNF [5] Viral protein interaction with cytokine and cytokine receptor, Type II diabetes mellitus, Type I diabetes mellitus, Yersinia infection, Tuberculosis D02597 Adalimumab [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271
114 TNF [5] Viral protein interaction with cytokine and cytokine receptor, Type II diabetes mellitus, Type I diabetes mellitus, Yersinia infection, Tuberculosis D02598 Infliximab [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271
115 TNF [5] Viral protein interaction with cytokine and cytokine receptor, Type II diabetes mellitus, Type I diabetes mellitus, Yersinia infection, Tuberculosis D03441 Certolizumab pegol [8] 37, 46, 49, 96, 97, 107, 226, 271
116 TNF [5] Viral protein interaction with cytokine and cytokine receptor, Type II diabetes mellitus, Type I diabetes mellitus, Yersinia infection, Tuberculosis D04358 Golimumab [8] 46, 56, 84, 96, 97, 107, 270, 271
117 TNF [5] Viral protein interaction with cytokine and cytokine receptor, Type II diabetes mellitus, Type I diabetes mellitus, Yersinia infection, Tuberculosis D04687 Lenalidomide [8] 16, 26, 28, 34, 49, 284, 300, 331
118 TNF [5] Viral protein interaction with cytokine and cytokine receptor, Type II diabetes mellitus, Type I diabetes mellitus, Yersinia infection, Tuberculosis D05393 Pegsunercept [1] 46
119 TNF [5] Viral protein interaction with cytokine and cytokine receptor, Type II diabetes mellitus, Type I diabetes mellitus, Yersinia infection, Tuberculosis D08976 Pomalidomide [5] 28, 51, 85, 227, 331
120 TNF [5] Viral protein interaction with cytokine and cytokine receptor, Type II diabetes mellitus, Type I diabetes mellitus, Yersinia infection, Tuberculosis D09944 Ozoralizumab [1] 46
121 C3 [2] Tuberculosis, Viral carcinogenesis D11613 Pegcetacoplan [4] 2, 61, 62, 222
122 VDR [1] Tuberculosis D00122 Calcifediol [2] 113, 299
123 VDR [1] Tuberculosis D00129 Calcitriol [9] 18, 37, 46, 49, 66, 96, 158, 235, 326
124 VDR [1] Tuberculosis D00187 Ergocalciferol [6] 46, 49, 84, 96, 97, 299
125 VDR [1] Tuberculosis D00188 Cholecalciferol [24] 6, 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 84, 85, 96, 97, 98, 162, 202, 228, 271, 298, 299
126 VDR [1] Tuberculosis D00299 Dihydrotachysterol [2] 6, 85
127 VDR [1] Tuberculosis D00930 Paricalcitol [5] 19, 66, 218, 238, 298
128 VDR [1] Tuberculosis D01125 Calcipotriol [2] 36, 51
129 VDR [1] Tuberculosis D01518 Alfacalcidol [8] 41, 46, 49, 50, 96, 107, 235, 238
130 VDR [1] Tuberculosis D07578 Eldecalcitol [1] 46
131 CASP9 [3] VEGF signaling pathway, Tuberculosis, Viral myocarditis D11195 Rimiducid [6] 19, 60, 65, 284, 285, 326
132 CD74 [1] Tuberculosis D08944 Milatuzumab [1] 49