DDrare
Disease
Drug
Target Gene/Pathway
問合せ先
EN
Target Gene/Pathway
Pathway
/
Gene
Search
A
B
C
D
E
F
G
H
I
J
K
L
M
N
O
P
Q
R
S
T
U
V
W
X
Y
Z
Other
Search results
10
50
100
ALL
entries per page:
Showing 1 to 10 of 38 entries
Filter by
Reset
|
No.
KEGG GENES
KEGG PATHWAY
KEGG DRUG
DrugBank
指定難病告示番号
1
CCR4
💬
1. CCR4
×
Name
Full Name
CCR4
C-C motif chemokine receptor 4
5件:
Cytokine-cytokine receptor interaction
Cytokine-cytokine receptor interaction
,
Viral protein interaction with cytokine and cytokine receptor
,
Chemokine signaling pathway
,
Kaposi sarcoma-associated herpesvirus infection
,
Viral carcinogenesis
5件:
Cytokine-cytokine receptor interaction
,
Viral protein interaction with cytokine and cytokine rec
...
Mogamulizumab
Mogamulizumab
💬
1. CCR4
×
Name
Other Names
Mogamulizumab
Mogamulizumab (USAN)
Mogamulizumab (genetical recombination) (JAN)
Mogamulizumab-kpkc
Poteligeo (TN)
モガムリズマブ
ポテリジオ
Mogamulizumab
1件:
26
26
💬
1. CCR4
×
告示番号
日本語名
英語名
26
HTLV-1関連脊髄症
HTLV-1-associated myelopathy
2
CCR5
💬
2. CCR5
×
Name
Full Name
CCR5
C-C motif chemokine receptor 5
11件:
Viral life cycle - HIV-1
Viral life cycle - HIV-1
,
Virion - Human immunodeficiency virus
,
Cytokine-cytokine receptor interaction
,
Viral protein interaction with cytokine and cytokine receptor
,
Chemokine signaling pathway
,
Endocytosis
,
Toxoplasmosis
,
Human cytomegalovirus infection
,
Kaposi sarcoma-associated herpesvirus infection
,
Human immunodeficiency virus 1 infection
,
Viral carcinogenesis
11件:
Viral life cycle - HIV-1
,
Virion - Human immunodeficiency virus
,
Cytokine-cytokine receptor int
...
Maraviroc
Maraviroc
💬
2. CCR5
×
Name
Other Names
Maraviroc
Maraviroc (JAN/INN)
Selzentry (TN)
マラビロク
マラビロック
シーエルセントリ
Maraviroc
2件:
46
46
,
84
💬
2. CCR5
×
告示番号
日本語名
英語名
46
悪性関節リウマチ
Malignant rheumatoid arthritis
84
サルコイドーシス
Sarcoidosis
3
CCR5
💬
3. CCR5
×
Name
Full Name
CCR5
C-C motif chemokine receptor 5
11件:
Viral life cycle - HIV-1
Viral life cycle - HIV-1
,
Virion - Human immunodeficiency virus
,
Cytokine-cytokine receptor interaction
,
Viral protein interaction with cytokine and cytokine receptor
,
Chemokine signaling pathway
,
Endocytosis
,
Toxoplasmosis
,
Human cytomegalovirus infection
,
Kaposi sarcoma-associated herpesvirus infection
,
Human immunodeficiency virus 1 infection
,
Viral carcinogenesis
11件:
Viral life cycle - HIV-1
,
Virion - Human immunodeficiency virus
,
Cytokine-cytokine receptor int
...
Cenicriviroc
Cenicriviroc
💬
3. CCR5
×
Name
Other Names
Cenicriviroc
Cenicriviroc (USAN/INN)
セニクリビロック
Cenicriviroc
1件:
94
94
💬
3. CCR5
×
告示番号
日本語名
英語名
94
原発性硬化性胆管炎
Primary sclerosing cholangitis
4
CSF1R
💬
4. CSF1R
×
Name
Full Name
CSF1R
colony stimulating factor 1 receptor
11件:
MAPK signaling pathway
MAPK signaling pathway
,
Ras signaling pathway
,
Rap1 signaling pathway
,
Cytokine-cytokine receptor interaction
,
Viral protein interaction with cytokine and cytokine receptor
,
PI3K-Akt signaling pathway
,
Osteoclast differentiation
,
Hematopoietic cell lineage
,
Pathways in cancer
,
Transcriptional misregulation in cancer
,
Acute myeloid leukemia
11件:
MAPK signaling pathway
,
Ras signaling pathway
,
Rap1 signaling pathway
,
Cytokine-cytokine recept
...
Sunitinib
Sunitinib
💬
4. CSF1R
×
Name
Other Names
Sunitinib
Sunitinib (INN)
スニチニブ
Sunitinib
2件:
28
28
,
34
💬
4. CSF1R
×
告示番号
日本語名
英語名
28
全身性アミロイドーシス
Systemic amyloidosis
34
神経線維腫症
Neurofibromatosis
5
CSF1R
💬
5. CSF1R
×
Name
Full Name
CSF1R
colony stimulating factor 1 receptor
11件:
MAPK signaling pathway
MAPK signaling pathway
,
Ras signaling pathway
,
Rap1 signaling pathway
,
Cytokine-cytokine receptor interaction
,
Viral protein interaction with cytokine and cytokine receptor
,
PI3K-Akt signaling pathway
,
Osteoclast differentiation
,
Hematopoietic cell lineage
,
Pathways in cancer
,
Transcriptional misregulation in cancer
,
Acute myeloid leukemia
11件:
MAPK signaling pathway
,
Ras signaling pathway
,
Rap1 signaling pathway
,
Cytokine-cytokine recept
...
Pexidartinib
Pexidartinib
💬
5. CSF1R
×
Name
Other Names
Pexidartinib
Pexidartinib (USAN/INN)
ペキシダルチニブ
Pexidartinib
1件:
34
34
💬
5. CSF1R
×
告示番号
日本語名
英語名
34
神経線維腫症
Neurofibromatosis
6
IL2RA
💬
6. IL2RA
×
Name
Full Name
IL2RA
interleukin 2 receptor subunit alpha
11件:
Cytokine-cytokine receptor interaction
Cytokine-cytokine receptor interaction
,
Viral protein interaction with cytokine and cytokine receptor
,
Endocytosis
,
PI3K-Akt signaling pathway
,
JAK-STAT signaling pathway
,
Hematopoietic cell lineage
,
Th1 and Th2 cell differentiation
,
Th17 cell differentiation
,
Measles
,
Human T-cell leukemia virus 1 infection
,
Pathways in cancer
11件:
Cytokine-cytokine receptor interaction
,
Viral protein interaction with cytokine and cytokine re
...
Aldesleukin
Aldesleukin
💬
6. IL2RA
×
Name
Other Names
Aldesleukin
Aldesleukin (USAN/INN)
Interleukin-2
Proleukin (TN)
アルデスロイキン
インターロイキン-2
Aldesleukin
6件:
2
2
,
35
,
49
,
65
,
96
,
97
💬
6. IL2RA
×
告示番号
日本語名
英語名
2
筋萎縮性側索硬化症
Amyotrophic lateral sclerosis
35
天疱瘡
Pemphigus
49
全身性エリテマトーデス
Systemic lupus erythematosus
65
原発性免疫不全症候群
Primary immunodeficiency
96
クローン病;回腸末端炎
Crohn disease
97
潰瘍性大腸炎
Ulcerative colitis
7
IL2RA
💬
7. IL2RA
×
Name
Full Name
IL2RA
interleukin 2 receptor subunit alpha
11件:
Cytokine-cytokine receptor interaction
Cytokine-cytokine receptor interaction
,
Viral protein interaction with cytokine and cytokine receptor
,
Endocytosis
,
PI3K-Akt signaling pathway
,
JAK-STAT signaling pathway
,
Hematopoietic cell lineage
,
Th1 and Th2 cell differentiation
,
Th17 cell differentiation
,
Measles
,
Human T-cell leukemia virus 1 infection
,
Pathways in cancer
11件:
Cytokine-cytokine receptor interaction
,
Viral protein interaction with cytokine and cytokine re
...
Basiliximab
Basiliximab
💬
7. IL2RA
×
Name
Other Names
Basiliximab
Basiliximab (USAN/INN)
Basiliximab (genetical recombination) (JAN)
Simulect (TN)
バシリキシマブ
シムレクト
Basiliximab
6件:
2
2
,
50
,
66
,
97
,
222
,
228
💬
7. IL2RA
×
告示番号
日本語名
英語名
2
筋萎縮性側索硬化症
Amyotrophic lateral sclerosis
50
皮膚筋炎/多発性筋炎
Dermatomyositis
66
IgA腎症
IgA nephropathy
97
潰瘍性大腸炎
Ulcerative colitis
222
一次性ネフローゼ症候群
Primary nephrotic syndrome
228
閉塞性細気管支炎
Bronchiolitis obliterans
8
IL2RA
💬
8. IL2RA
×
Name
Full Name
IL2RA
interleukin 2 receptor subunit alpha
11件:
Cytokine-cytokine receptor interaction
Cytokine-cytokine receptor interaction
,
Viral protein interaction with cytokine and cytokine receptor
,
Endocytosis
,
PI3K-Akt signaling pathway
,
JAK-STAT signaling pathway
,
Hematopoietic cell lineage
,
Th1 and Th2 cell differentiation
,
Th17 cell differentiation
,
Measles
,
Human T-cell leukemia virus 1 infection
,
Pathways in cancer
11件:
Cytokine-cytokine receptor interaction
,
Viral protein interaction with cytokine and cytokine re
...
Daclizumab
Daclizumab
💬
8. IL2RA
×
Name
Other Names
Daclizumab
Daclizumab (USAN/INN)
Zenapax (TN)
Zinbryta (TN)
ダクリズマブ
Daclizumab
8件:
13
13
,
56
,
60
,
65
,
97
,
107
,
283
,
284
💬
8. IL2RA
×
告示番号
日本語名
英語名
13
多発性硬化症/視神経脊髄炎
Multiple sclerosis/Neuromyelitis optica
56
ベーチェット病
Behcet disease
60
再生不良性貧血
Aplastic anemia
65
原発性免疫不全症候群
Primary immunodeficiency
97
潰瘍性大腸炎
Ulcerative colitis
107
若年性特発性関節炎
Juvenile idiopathic arthritis
283
後天性赤芽球癆
Acquired pure red cell aplasia
284
ダイアモンド・ブラックファン貧血
Diamond-Blackfan anemia
9
IL2RB
💬
9. IL2RB
×
Name
Full Name
IL2RB
interleukin 2 receptor subunit beta
11件:
Cytokine-cytokine receptor interaction
Cytokine-cytokine receptor interaction
,
Viral protein interaction with cytokine and cytokine receptor
,
Endocytosis
,
PI3K-Akt signaling pathway
,
JAK-STAT signaling pathway
,
Th1 and Th2 cell differentiation
,
Th17 cell differentiation
,
Measles
,
Human T-cell leukemia virus 1 infection
,
Pathways in cancer
,
Transcriptional misregulation in cancer
11件:
Cytokine-cytokine receptor interaction
,
Viral protein interaction with cytokine and cytokine re
...
Aldesleukin
Aldesleukin
💬
9. IL2RB
×
Name
Other Names
Aldesleukin
Aldesleukin (USAN/INN)
Interleukin-2
Proleukin (TN)
アルデスロイキン
インターロイキン-2
Aldesleukin
6件:
2
2
,
35
,
49
,
65
,
96
,
97
💬
9. IL2RB
×
告示番号
日本語名
英語名
2
筋萎縮性側索硬化症
Amyotrophic lateral sclerosis
35
天疱瘡
Pemphigus
49
全身性エリテマトーデス
Systemic lupus erythematosus
65
原発性免疫不全症候群
Primary immunodeficiency
96
クローン病;回腸末端炎
Crohn disease
97
潰瘍性大腸炎
Ulcerative colitis
10
IL2RG
💬
10. IL2RG
×
Name
Full Name
IL2RG
interleukin 2 receptor subunit gamma
12件:
Cytokine-cytokine receptor interaction
Cytokine-cytokine receptor interaction
,
Viral protein interaction with cytokine and cytokine receptor
,
Endocytosis
,
PI3K-Akt signaling pathway
,
JAK-STAT signaling pathway
,
Th1 and Th2 cell differentiation
,
Th17 cell differentiation
,
Measles
,
Human T-cell leukemia virus 1 infection
,
Pathways in cancer
,
Inflammatory bowel disease
,
Primary immunodeficiency
12件:
Cytokine-cytokine receptor interaction
,
Viral protein interaction with cytokine and cytokine re
...
Aldesleukin
Aldesleukin
💬
10. IL2RG
×
Name
Other Names
Aldesleukin
Aldesleukin (USAN/INN)
Interleukin-2
Proleukin (TN)
アルデスロイキン
インターロイキン-2
Aldesleukin
6件:
2
2
,
35
,
49
,
65
,
96
,
97
💬
10. IL2RG
×
告示番号
日本語名
英語名
2
筋萎縮性側索硬化症
Amyotrophic lateral sclerosis
35
天疱瘡
Pemphigus
49
全身性エリテマトーデス
Systemic lupus erythematosus
65
原発性免疫不全症候群
Primary immunodeficiency
96
クローン病;回腸末端炎
Crohn disease
97
潰瘍性大腸炎
Ulcerative colitis