Target Gene/Pathway Pathway / Gene

  

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No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank 指定難病告示番号
1 ABAT 💬 6件: Alanine, aspartate and glutamate metabolism, Valine, leucine and isoleucine degradation, beta-Alanine metabolism, Propanoate metabolism, Butanoate metabolism, GABAergic synapse Valproic acid 💬 Valproic acid 11件: 3, 5, 26, 34, 51, 65, 89, 90, 145, 222, 331 💬
2 ABAT 💬 6件: Alanine, aspartate and glutamate metabolism, Valine, leucine and isoleucine degradation, beta-Alanine metabolism, Propanoate metabolism, Butanoate metabolism, GABAergic synapse Valproate sodium 💬 Valproic acid 11件: 3, 5, 26, 34, 51, 65, 89, 90, 145, 222, 331 💬
3 ABAT 💬 6件: Alanine, aspartate and glutamate metabolism, Valine, leucine and isoleucine degradation, beta-Alanine metabolism, Propanoate metabolism, Butanoate metabolism, GABAergic synapse Divalproex sodium 💬 Valproic acid 11件: 3, 5, 26, 34, 51, 65, 89, 90, 145, 222, 331 💬
4 ADRA2A 💬 4件: cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling Brimonidine 💬 Brimonidine 2件: 13, 90 💬
5 ADRA2A 💬 4件: cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling Brimonidine tartrate 💬 Brimonidine 2件: 13, 90 💬
6 ADRA2B 💬 4件: cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling Brimonidine tartrate 💬 Brimonidine 2件: 13, 90 💬
7 ADRA2B 💬 4件: cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling Brimonidine 💬 Brimonidine 2件: 13, 90 💬
8 ADRA2C 💬 4件: cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling Brimonidine tartrate 💬 Brimonidine 2件: 13, 90 💬
9 ADRA2C 💬 4件: cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling Brimonidine 💬 Brimonidine 2件: 13, 90 💬
10 ALDH1B1 💬 13件: Glycolysis / Gluconeogenesis, Ascorbate and aldarate metabolism, Fatty acid degradation, Valine, leucine and isoleucine degradation, Lysine degradation, Arginine and proline metabolism, Histidine metabolism, Tryptophan metabolism, beta-Alanine metabolism, Glycerolipid metabolism, Pyruvate metabolism, Pantothenate and CoA biosynthesis, Alcoholic liver disease Disulfiram 💬 Disulfiram 3件: 46, 90, 301 💬
11 ALDH2 💬 13件: Glycolysis / Gluconeogenesis, Ascorbate and aldarate metabolism, Fatty acid degradation, Valine, leucine and isoleucine degradation, Lysine degradation, Arginine and proline metabolism, Histidine metabolism, Tryptophan metabolism, beta-Alanine metabolism, Glycerolipid metabolism, Pyruvate metabolism, Pantothenate and CoA biosynthesis, Alcoholic liver disease Disulfiram 💬 Disulfiram 3件: 46, 90, 301 💬
12 ALDH3A2 💬 13件: Glycolysis / Gluconeogenesis, Ascorbate and aldarate metabolism, Fatty acid degradation, Valine, leucine and isoleucine degradation, Lysine degradation, Arginine and proline metabolism, Histidine metabolism, Tryptophan metabolism, beta-Alanine metabolism, Glycerolipid metabolism, Pyruvate metabolism, Pantothenate and CoA biosynthesis, Alcoholic liver disease Disulfiram 💬 Disulfiram 3件: 46, 90, 301 💬
13 ALDH5A1 💬 2件: Alanine, aspartate and glutamate metabolism, Butanoate metabolism Valproic acid 💬 Valproic acid 11件: 3, 5, 26, 34, 51, 65, 89, 90, 145, 222, 331 💬
14 ALDH5A1 💬 2件: Alanine, aspartate and glutamate metabolism, Butanoate metabolism Valproate sodium 💬 Valproic acid 11件: 3, 5, 26, 34, 51, 65, 89, 90, 145, 222, 331 💬
15 ALDH5A1 💬 2件: Alanine, aspartate and glutamate metabolism, Butanoate metabolism Divalproex sodium 💬 Valproic acid 11件: 3, 5, 26, 34, 51, 65, 89, 90, 145, 222, 331 💬
16 ATP4A 💬 3件: Oxidative phosphorylation, Collecting duct acid secretion, Gastric acid secretion Omeprazole sodium 💬 Omeprazole 18件: 6, 8, 13, 21, 46, 51, 67, 85, 90, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬
17 ATP4A 💬 3件: Oxidative phosphorylation, Collecting duct acid secretion, Gastric acid secretion Omeprazole 💬 Omeprazole 18件: 6, 8, 13, 21, 46, 51, 67, 85, 90, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬
18 ATP4A 💬 3件: Oxidative phosphorylation, Collecting duct acid secretion, Gastric acid secretion Omeprazole magnesium 💬 Omeprazole 18件: 6, 8, 13, 21, 46, 51, 67, 85, 90, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬
19 ATP4B 💬 3件: Oxidative phosphorylation, Collecting duct acid secretion, Gastric acid secretion Omeprazole magnesium 💬 Omeprazole 18件: 6, 8, 13, 21, 46, 51, 67, 85, 90, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬
20 ATP4B 💬 3件: Oxidative phosphorylation, Collecting duct acid secretion, Gastric acid secretion Omeprazole sodium 💬 Omeprazole 18件: 6, 8, 13, 21, 46, 51, 67, 85, 90, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬
21 ATP4B 💬 3件: Oxidative phosphorylation, Collecting duct acid secretion, Gastric acid secretion Omeprazole 💬 Omeprazole 18件: 6, 8, 13, 21, 46, 51, 67, 85, 90, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬
22 CA1 💬 1件: Nitrogen metabolism Dorzolamide hydrochloride 💬 Dorzolamide 1件: 90 💬
23 CA1 💬 1件: Nitrogen metabolism Acetazolamide 💬 Acetazolamide 8件: 13, 67, 90, 115, 155, 222, 225, 230 💬
24 CA1 💬 1件: Nitrogen metabolism Dorzolamide 💬 Dorzolamide 1件: 90 💬
25 CA1 💬 1件: Nitrogen metabolism Acetazolamide sodium 💬 Acetazolamide 8件: 13, 67, 90, 115, 155, 222, 225, 230 💬
26 CA12 💬 1件: Nitrogen metabolism Dorzolamide 💬 Dorzolamide 1件: 90 💬
27 CA12 💬 1件: Nitrogen metabolism Acetazolamide 💬 Acetazolamide 8件: 13, 67, 90, 115, 155, 222, 225, 230 💬
28 CA12 💬 1件: Nitrogen metabolism Dorzolamide hydrochloride 💬 Dorzolamide 1件: 90 💬
29 CA12 💬 1件: Nitrogen metabolism Acetazolamide sodium 💬 Acetazolamide 8件: 13, 67, 90, 115, 155, 222, 225, 230 💬
30 CA13 💬 1件: Nitrogen metabolism Acetazolamide 💬 Acetazolamide 8件: 13, 67, 90, 115, 155, 222, 225, 230 💬
31 CA13 💬 1件: Nitrogen metabolism Dorzolamide hydrochloride 💬 Dorzolamide 1件: 90 💬
32 CA13 💬 1件: Nitrogen metabolism Dorzolamide 💬 Dorzolamide 1件: 90 💬
33 CA13 💬 1件: Nitrogen metabolism Acetazolamide sodium 💬 Acetazolamide 8件: 13, 67, 90, 115, 155, 222, 225, 230 💬
34 CA14 💬 1件: Nitrogen metabolism Acetazolamide sodium 💬 Acetazolamide 8件: 13, 67, 90, 115, 155, 222, 225, 230 💬
35 CA14 💬 1件: Nitrogen metabolism Acetazolamide 💬 Acetazolamide 8件: 13, 67, 90, 115, 155, 222, 225, 230 💬
36 CA14 💬 1件: Nitrogen metabolism Dorzolamide 💬 Dorzolamide 1件: 90 💬
37 CA14 💬 1件: Nitrogen metabolism Dorzolamide hydrochloride 💬 Dorzolamide 1件: 90 💬
38 CA2 💬 6件: Nitrogen metabolism, Proximal tubule bicarbonate reclamation, Collecting duct acid secretion, Gastric acid secretion, Pancreatic secretion, Bile secretion Acetazolamide sodium 💬 Acetazolamide 8件: 13, 67, 90, 115, 155, 222, 225, 230 💬
39 CA2 💬 6件: Nitrogen metabolism, Proximal tubule bicarbonate reclamation, Collecting duct acid secretion, Gastric acid secretion, Pancreatic secretion, Bile secretion Dorzolamide hydrochloride 💬 Dorzolamide 1件: 90 💬
40 CA2 💬 6件: Nitrogen metabolism, Proximal tubule bicarbonate reclamation, Collecting duct acid secretion, Gastric acid secretion, Pancreatic secretion, Bile secretion Acetazolamide 💬 Acetazolamide 8件: 13, 67, 90, 115, 155, 222, 225, 230 💬
41 CA2 💬 6件: Nitrogen metabolism, Proximal tubule bicarbonate reclamation, Collecting duct acid secretion, Gastric acid secretion, Pancreatic secretion, Bile secretion Dorzolamide 💬 Dorzolamide 1件: 90 💬
42 CA3 💬 1件: Nitrogen metabolism Acetazolamide 💬 Acetazolamide 8件: 13, 67, 90, 115, 155, 222, 225, 230 💬
43 CA3 💬 1件: Nitrogen metabolism Dorzolamide 💬 Dorzolamide 1件: 90 💬
44 CA3 💬 1件: Nitrogen metabolism Acetazolamide sodium 💬 Acetazolamide 8件: 13, 67, 90, 115, 155, 222, 225, 230 💬
45 CA3 💬 1件: Nitrogen metabolism Dorzolamide hydrochloride 💬 Dorzolamide 1件: 90 💬
46 CA4 💬 2件: Nitrogen metabolism, Proximal tubule bicarbonate reclamation Acetazolamide 💬 Acetazolamide 8件: 13, 67, 90, 115, 155, 222, 225, 230 💬
47 CA4 💬 2件: Nitrogen metabolism, Proximal tubule bicarbonate reclamation Dorzolamide hydrochloride 💬 Dorzolamide 1件: 90 💬
48 CA4 💬 2件: Nitrogen metabolism, Proximal tubule bicarbonate reclamation Acetazolamide sodium 💬 Acetazolamide 8件: 13, 67, 90, 115, 155, 222, 225, 230 💬
49 CA4 💬 2件: Nitrogen metabolism, Proximal tubule bicarbonate reclamation Dorzolamide 💬 Dorzolamide 1件: 90 💬
50 CA5A 💬 1件: Nitrogen metabolism Acetazolamide sodium 💬 Acetazolamide 8件: 13, 67, 90, 115, 155, 222, 225, 230 💬
51 CA5A 💬 1件: Nitrogen metabolism Acetazolamide 💬 Acetazolamide 8件: 13, 67, 90, 115, 155, 222, 225, 230 💬
52 CA5A 💬 1件: Nitrogen metabolism Dorzolamide hydrochloride 💬 Dorzolamide 1件: 90 💬
53 CA5A 💬 1件: Nitrogen metabolism Dorzolamide 💬 Dorzolamide 1件: 90 💬
54 CA5B 💬 1件: Nitrogen metabolism Dorzolamide hydrochloride 💬 Dorzolamide 1件: 90 💬
55 CA5B 💬 1件: Nitrogen metabolism Dorzolamide 💬 Dorzolamide 1件: 90 💬
56 CA5B 💬 1件: Nitrogen metabolism Acetazolamide sodium 💬 Acetazolamide 8件: 13, 67, 90, 115, 155, 222, 225, 230 💬
57 CA5B 💬 1件: Nitrogen metabolism Acetazolamide 💬 Acetazolamide 8件: 13, 67, 90, 115, 155, 222, 225, 230 💬
58 CA6 💬 1件: Nitrogen metabolism Dorzolamide 💬 Dorzolamide 1件: 90 💬
59 CA6 💬 1件: Nitrogen metabolism Acetazolamide sodium 💬 Acetazolamide 8件: 13, 67, 90, 115, 155, 222, 225, 230 💬
60 CA6 💬 1件: Nitrogen metabolism Acetazolamide 💬 Acetazolamide 8件: 13, 67, 90, 115, 155, 222, 225, 230 💬
61 CA6 💬 1件: Nitrogen metabolism Dorzolamide hydrochloride 💬 Dorzolamide 1件: 90 💬
62 CA7 💬 1件: Nitrogen metabolism Acetazolamide sodium 💬 Acetazolamide 8件: 13, 67, 90, 115, 155, 222, 225, 230 💬
63 CA7 💬 1件: Nitrogen metabolism Dorzolamide hydrochloride 💬 Dorzolamide 1件: 90 💬
64 CA7 💬 1件: Nitrogen metabolism Dorzolamide 💬 Dorzolamide 1件: 90 💬
65 CA7 💬 1件: Nitrogen metabolism Acetazolamide 💬 Acetazolamide 8件: 13, 67, 90, 115, 155, 222, 225, 230 💬
66 CA8 💬 1件: Nitrogen metabolism Dorzolamide 💬 Dorzolamide 1件: 90 💬
67 CA8 💬 1件: Nitrogen metabolism Acetazolamide sodium 💬 Acetazolamide 8件: 13, 67, 90, 115, 155, 222, 225, 230 💬
68 CA8 💬 1件: Nitrogen metabolism Acetazolamide 💬 Acetazolamide 8件: 13, 67, 90, 115, 155, 222, 225, 230 💬
69 CA8 💬 1件: Nitrogen metabolism Dorzolamide hydrochloride 💬 Dorzolamide 1件: 90 💬
70 CA9 💬 1件: Nitrogen metabolism Acetazolamide 💬 Acetazolamide 8件: 13, 67, 90, 115, 155, 222, 225, 230 💬
71 CA9 💬 1件: Nitrogen metabolism Dorzolamide 💬 Dorzolamide 1件: 90 💬
72 CA9 💬 1件: Nitrogen metabolism Dorzolamide hydrochloride 💬 Dorzolamide 1件: 90 💬
73 CA9 💬 1件: Nitrogen metabolism Acetazolamide sodium 💬 Acetazolamide 8件: 13, 67, 90, 115, 155, 222, 225, 230 💬
74 CACNA1C 💬 34件: MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Circadian entrainment, Long-term potentiation, Retrograde endocannabinoid signaling, Glutamatergic synapse, Cholinergic synapse, Serotonergic synapse, GABAergic synapse, Dopaminergic synapse, Taste transduction, Insulin secretion, GnRH signaling pathway, Oxytocin signaling pathway, Renin secretion, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Type II diabetes mellitus, Cushing syndrome, Growth hormone synthesis, secretion and action, Alzheimer disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Chemical carcinogenesis - receptor activation, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Nilvadipine 💬 Nilvadipine 1件: 90 💬
75 CACNA1D 💬 35件: MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Cellular senescence, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Tight junction, Circadian entrainment, Retrograde endocannabinoid signaling, Glutamatergic synapse, Cholinergic synapse, Serotonergic synapse, GABAergic synapse, Dopaminergic synapse, Insulin secretion, GnRH signaling pathway, Oxytocin signaling pathway, Renin secretion, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Type II diabetes mellitus, Cushing syndrome, Growth hormone synthesis, secretion and action, Carbohydrate digestion and absorption, Alzheimer disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Chemical carcinogenesis - receptor activation, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Nilvadipine 💬 Nilvadipine 1件: 90 💬
76 CACNA1F 💬 27件: MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Cholinergic synapse, Serotonergic synapse, GABAergic synapse, Insulin secretion, GnRH signaling pathway, Oxytocin signaling pathway, Renin secretion, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Cushing syndrome, Growth hormone synthesis, secretion and action, Alzheimer disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Chemical carcinogenesis - receptor activation, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Nilvadipine 💬 Nilvadipine 1件: 90 💬
77 CACNA1G 💬 8件: MAPK signaling pathway, Calcium signaling pathway, Circadian entrainment, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Type II diabetes mellitus, Cushing syndrome Valproic acid 💬 Valproic acid 11件: 3, 5, 26, 34, 51, 65, 89, 90, 145, 222, 331 💬
78 CACNA1G 💬 8件: MAPK signaling pathway, Calcium signaling pathway, Circadian entrainment, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Type II diabetes mellitus, Cushing syndrome Divalproex sodium 💬 Valproic acid 11件: 3, 5, 26, 34, 51, 65, 89, 90, 145, 222, 331 💬
79 CACNA1G 💬 8件: MAPK signaling pathway, Calcium signaling pathway, Circadian entrainment, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Type II diabetes mellitus, Cushing syndrome Valproate sodium 💬 Valproic acid 11件: 3, 5, 26, 34, 51, 65, 89, 90, 145, 222, 331 💬
80 CACNA1H 💬 7件: MAPK signaling pathway, Calcium signaling pathway, Circadian entrainment, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Cushing syndrome Valproate sodium 💬 Valproic acid 11件: 3, 5, 26, 34, 51, 65, 89, 90, 145, 222, 331 💬
81 CACNA1H 💬 7件: MAPK signaling pathway, Calcium signaling pathway, Circadian entrainment, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Cushing syndrome Divalproex sodium 💬 Valproic acid 11件: 3, 5, 26, 34, 51, 65, 89, 90, 145, 222, 331 💬
82 CACNA1H 💬 7件: MAPK signaling pathway, Calcium signaling pathway, Circadian entrainment, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Cushing syndrome Valproic acid 💬 Valproic acid 11件: 3, 5, 26, 34, 51, 65, 89, 90, 145, 222, 331 💬
83 CACNA1I 💬 7件: MAPK signaling pathway, Calcium signaling pathway, Circadian entrainment, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Cushing syndrome Valproic acid 💬 Valproic acid 11件: 3, 5, 26, 34, 51, 65, 89, 90, 145, 222, 331 💬
84 CACNA1I 💬 7件: MAPK signaling pathway, Calcium signaling pathway, Circadian entrainment, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Cushing syndrome Divalproex sodium 💬 Valproic acid 11件: 3, 5, 26, 34, 51, 65, 89, 90, 145, 222, 331 💬
85 CACNA1I 💬 7件: MAPK signaling pathway, Calcium signaling pathway, Circadian entrainment, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Cushing syndrome Valproate sodium 💬 Valproic acid 11件: 3, 5, 26, 34, 51, 65, 89, 90, 145, 222, 331 💬
86 CACNA1S 💬 27件: MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Cholinergic synapse, Serotonergic synapse, GABAergic synapse, Insulin secretion, GnRH signaling pathway, Oxytocin signaling pathway, Renin secretion, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Cushing syndrome, Growth hormone synthesis, secretion and action, Alzheimer disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Chemical carcinogenesis - receptor activation, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy Nilvadipine 💬 Nilvadipine 1件: 90 💬
87 DDC 💬 8件: Tyrosine metabolism, Phenylalanine metabolism, Tryptophan metabolism, Serotonergic synapse, Dopaminergic synapse, Cocaine addiction, Amphetamine addiction, Alcoholism Carbidopa 💬 Carbidopa 7件: 6, 13, 17, 90, 140, 164, 201 💬
88 DRD1 💬 12件: Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Amphetamine addiction, Morphine addiction, Alcoholism Levodopa 💬 Levodopa 8件: 5, 6, 17, 90, 120, 140, 164, 201 💬
89 DRD2 💬 10件: Rap1 signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Alcoholism Levodopa 💬 Levodopa 8件: 5, 6, 17, 90, 120, 140, 164, 201 💬
90 DRD3 💬 4件: Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Dopaminergic synapse Levodopa 💬 Levodopa 8件: 5, 6, 17, 90, 120, 140, 164, 201 💬
91 DRD4 💬 4件: Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Dopaminergic synapse Levodopa 💬 Levodopa 8件: 5, 6, 17, 90, 120, 140, 164, 201 💬
92 DRD5 💬 6件: Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Dopaminergic synapse Levodopa 💬 Levodopa 8件: 5, 6, 17, 90, 120, 140, 164, 201 💬
93 GAD1 💬 6件: Alanine, aspartate and glutamate metabolism, beta-Alanine metabolism, Taurine and hypotaurine metabolism, Butanoate metabolism, GABAergic synapse, Type I diabetes mellitus Divalproex sodium 💬 Valproic acid 11件: 3, 5, 26, 34, 51, 65, 89, 90, 145, 222, 331 💬
94 GAD1 💬 6件: Alanine, aspartate and glutamate metabolism, beta-Alanine metabolism, Taurine and hypotaurine metabolism, Butanoate metabolism, GABAergic synapse, Type I diabetes mellitus Valproate sodium 💬 Valproic acid 11件: 3, 5, 26, 34, 51, 65, 89, 90, 145, 222, 331 💬
95 GAD1 💬 6件: Alanine, aspartate and glutamate metabolism, beta-Alanine metabolism, Taurine and hypotaurine metabolism, Butanoate metabolism, GABAergic synapse, Type I diabetes mellitus Valproic acid 💬 Valproic acid 11件: 3, 5, 26, 34, 51, 65, 89, 90, 145, 222, 331 💬
96 GAD2 💬 6件: Alanine, aspartate and glutamate metabolism, beta-Alanine metabolism, Taurine and hypotaurine metabolism, Butanoate metabolism, GABAergic synapse, Type I diabetes mellitus Valproate sodium 💬 Valproic acid 11件: 3, 5, 26, 34, 51, 65, 89, 90, 145, 222, 331 💬
97 GAD2 💬 6件: Alanine, aspartate and glutamate metabolism, beta-Alanine metabolism, Taurine and hypotaurine metabolism, Butanoate metabolism, GABAergic synapse, Type I diabetes mellitus Valproic acid 💬 Valproic acid 11件: 3, 5, 26, 34, 51, 65, 89, 90, 145, 222, 331 💬
98 GAD2 💬 6件: Alanine, aspartate and glutamate metabolism, beta-Alanine metabolism, Taurine and hypotaurine metabolism, Butanoate metabolism, GABAergic synapse, Type I diabetes mellitus Divalproex sodium 💬 Valproic acid 11件: 3, 5, 26, 34, 51, 65, 89, 90, 145, 222, 331 💬
99 HMGCR 💬 3件: Terpenoid backbone biosynthesis, AMPK signaling pathway, Bile secretion Pitavastatin magnesium 💬 Pitavastatin 4件: 49, 71, 79, 90 💬
100 HMGCR 💬 3件: Terpenoid backbone biosynthesis, AMPK signaling pathway, Bile secretion Pitavastatin calcium 💬 Pitavastatin 4件: 49, 71, 79, 90 💬
101 MTNR1A 💬 2件: Neuroactive ligand-receptor interaction, Circadian entrainment Melatonin 💬 Melatonin 18件: 2, 6, 8, 13, 37, 46, 49, 72, 78, 86, 90, 96, 97, 145, 149, 159, 202, 265 💬
102 MTNR1B 💬 2件: Neuroactive ligand-receptor interaction, Circadian entrainment Melatonin 💬 Melatonin 18件: 2, 6, 8, 13, 37, 46, 49, 72, 78, 86, 90, 96, 97, 145, 149, 159, 202, 265 💬
103 NR3C1 💬 1件: Neuroactive ligand-receptor interaction Dexamethasone phosphate 💬 Dexamethasone 29件: 13, 14, 16, 19, 28, 35, 46, 53, 63, 64, 65, 70, 71, 74, 75, 81, 84, 90, 96, 97, 162, 222, 223, 235, 257, 283, 296, 299, 331 💬
104 NR3C1 💬 1件: Neuroactive ligand-receptor interaction Betamethasone dipropionate 💬 Betamethasone 9件: 2, 28, 46, 56, 65, 83, 90, 96, 235 💬
105 NR3C1 💬 1件: Neuroactive ligand-receptor interaction Dexamethasone 💬 Dexamethasone 29件: 13, 14, 16, 19, 28, 35, 46, 53, 63, 64, 65, 70, 71, 74, 75, 81, 84, 90, 96, 97, 162, 222, 223, 235, 257, 283, 296, 299, 331 💬
106 NR3C1 💬 1件: Neuroactive ligand-receptor interaction Dexamethasone sodium phosphate 💬 Dexamethasone 29件: 13, 14, 16, 19, 28, 35, 46, 53, 63, 64, 65, 70, 71, 74, 75, 81, 84, 90, 96, 97, 162, 222, 223, 235, 257, 283, 296, 299, 331 💬
107 NR3C1 💬 1件: Neuroactive ligand-receptor interaction Betamethasone sodium phosphate 💬 Betamethasone 9件: 2, 28, 46, 56, 65, 83, 90, 96, 235 💬
108 NR3C1 💬 1件: Neuroactive ligand-receptor interaction Betamethasone 💬 Betamethasone 9件: 2, 28, 46, 56, 65, 83, 90, 96, 235 💬
109 NR3C1 💬 1件: Neuroactive ligand-receptor interaction Triamcinolone 💬 Triamcinolone 11件: 35, 46, 53, 56, 70, 90, 96, 107, 162, 226, 298 💬
110 NR3C1 💬 1件: Neuroactive ligand-receptor interaction Prednisone 💬 Prednisone 58件: 2, 11, 13, 14, 18, 19, 26, 28, 35, 40, 41, 42, 43, 44, 45, 46, 48, 49, 50, 51, 53, 60, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 90, 93, 95, 96, 97, 113, 127, 145, 162, 164, 205, 222, 223, 224, 228, 251, 269, 283, 284, 285, 288, 299, 300, 303, 307, 331 💬
111 NR3C1 💬 1件: Neuroactive ligand-receptor interaction Triamcinolone acetonide 💬 Triamcinolone 11件: 35, 46, 53, 56, 70, 90, 96, 107, 162, 226, 298 💬
112 NR3C1 💬 1件: Neuroactive ligand-receptor interaction Triamcinolone diacetate 💬 Triamcinolone 11件: 35, 46, 53, 56, 70, 90, 96, 107, 162, 226, 298 💬
113 NR3C1 💬 1件: Neuroactive ligand-receptor interaction Betamethasone valerate 💬 Betamethasone 9件: 2, 28, 46, 56, 65, 83, 90, 96, 235 💬
114 NR3C1 💬 1件: Neuroactive ligand-receptor interaction Betamethasone benzoate 💬 Betamethasone 9件: 2, 28, 46, 56, 65, 83, 90, 96, 235 💬
115 NR3C1 💬 1件: Neuroactive ligand-receptor interaction Triamcinolone hexacetonide 💬 Triamcinolone 11件: 35, 46, 53, 56, 70, 90, 96, 107, 162, 226, 298 💬
116 NR3C1 💬 1件: Neuroactive ligand-receptor interaction Fluocinolone acetonide 💬 Fluocinolone acetonide 1件: 90 💬
117 NR3C1 💬 1件: Neuroactive ligand-receptor interaction Betamethasone acetate 💬 Betamethasone 9件: 2, 28, 46, 56, 65, 83, 90, 96, 235 💬
118 PDE5A 💬 2件: Purine metabolism, cGMP-PKG signaling pathway Sildenafil citrate 💬 Sildenafil 17件: 6, 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬
119 PDE5A 💬 2件: Purine metabolism, cGMP-PKG signaling pathway Sildenafil 💬 Sildenafil 17件: 6, 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬
120 PGF 💬 7件: MAPK signaling pathway, Ras signaling pathway, Rap1 signaling pathway, PI3K-Akt signaling pathway, Focal adhesion, Integrin signaling, Pathways in cancer Aflibercept 💬 Aflibercept 2件: 90, 166 💬
121 PPP3CA 💬 33件: MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, Oocyte meiosis, Cellular senescence, Wnt signaling pathway, Axon guidance, VEGF signaling pathway, Osteoclast differentiation, C-type lectin receptor signaling pathway, Natural killer cell mediated cytotoxicity, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, B cell receptor signaling pathway, Long-term potentiation, Glutamatergic synapse, Dopaminergic synapse, Oxytocin signaling pathway, Glucagon signaling pathway, Renin secretion, Alzheimer disease, Amyotrophic lateral sclerosis, Prion disease, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Tuberculosis, Human cytomegalovirus infection, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Human immunodeficiency virus 1 infection, PD-L1 expression and PD-1 checkpoint pathway in cancer, Lipid and atherosclerosis Cyclosporine 💬 Cyclosporine 39件: 11, 14, 19, 20, 28, 36, 40, 41, 42, 45, 46, 49, 50, 53, 56, 58, 60, 61, 62, 63, 64, 65, 67, 90, 95, 97, 107, 118, 162, 164, 222, 223, 226, 228, 234, 283, 284, 285, 302 💬
122 PPP3CB 💬 33件: MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, Oocyte meiosis, Cellular senescence, Wnt signaling pathway, Axon guidance, VEGF signaling pathway, Osteoclast differentiation, C-type lectin receptor signaling pathway, Natural killer cell mediated cytotoxicity, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, B cell receptor signaling pathway, Long-term potentiation, Glutamatergic synapse, Dopaminergic synapse, Oxytocin signaling pathway, Glucagon signaling pathway, Renin secretion, Alzheimer disease, Amyotrophic lateral sclerosis, Prion disease, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Tuberculosis, Human cytomegalovirus infection, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Human immunodeficiency virus 1 infection, PD-L1 expression and PD-1 checkpoint pathway in cancer, Lipid and atherosclerosis Cyclosporine 💬 Cyclosporine 39件: 11, 14, 19, 20, 28, 36, 40, 41, 42, 45, 46, 49, 50, 53, 56, 58, 60, 61, 62, 63, 64, 65, 67, 90, 95, 97, 107, 118, 162, 164, 222, 223, 226, 228, 234, 283, 284, 285, 302 💬
123 PPP3CC 💬 33件: MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, Oocyte meiosis, Cellular senescence, Wnt signaling pathway, Axon guidance, VEGF signaling pathway, Osteoclast differentiation, C-type lectin receptor signaling pathway, Natural killer cell mediated cytotoxicity, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, B cell receptor signaling pathway, Long-term potentiation, Glutamatergic synapse, Dopaminergic synapse, Oxytocin signaling pathway, Glucagon signaling pathway, Renin secretion, Alzheimer disease, Amyotrophic lateral sclerosis, Prion disease, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Tuberculosis, Human cytomegalovirus infection, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Human immunodeficiency virus 1 infection, PD-L1 expression and PD-1 checkpoint pathway in cancer, Lipid and atherosclerosis Cyclosporine 💬 Cyclosporine 39件: 11, 14, 19, 20, 28, 36, 40, 41, 42, 45, 46, 49, 50, 53, 56, 58, 60, 61, 62, 63, 64, 65, 67, 90, 95, 97, 107, 118, 162, 164, 222, 223, 226, 228, 234, 283, 284, 285, 302 💬
124 PPP3R1 💬 32件: MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, Oocyte meiosis, Cellular senescence, Wnt signaling pathway, Axon guidance, VEGF signaling pathway, Osteoclast differentiation, C-type lectin receptor signaling pathway, Natural killer cell mediated cytotoxicity, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, B cell receptor signaling pathway, Long-term potentiation, Glutamatergic synapse, Oxytocin signaling pathway, Glucagon signaling pathway, Renin secretion, Alzheimer disease, Amyotrophic lateral sclerosis, Prion disease, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Tuberculosis, Human cytomegalovirus infection, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Human immunodeficiency virus 1 infection, PD-L1 expression and PD-1 checkpoint pathway in cancer, Lipid and atherosclerosis Cyclosporine 💬 Cyclosporine 39件: 11, 14, 19, 20, 28, 36, 40, 41, 42, 45, 46, 49, 50, 53, 56, 58, 60, 61, 62, 63, 64, 65, 67, 90, 95, 97, 107, 118, 162, 164, 222, 223, 226, 228, 234, 283, 284, 285, 302 💬
125 PPP3R2 💬 32件: MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, Oocyte meiosis, Cellular senescence, Wnt signaling pathway, Axon guidance, VEGF signaling pathway, Osteoclast differentiation, C-type lectin receptor signaling pathway, Natural killer cell mediated cytotoxicity, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, B cell receptor signaling pathway, Long-term potentiation, Glutamatergic synapse, Oxytocin signaling pathway, Glucagon signaling pathway, Renin secretion, Alzheimer disease, Amyotrophic lateral sclerosis, Prion disease, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Tuberculosis, Human cytomegalovirus infection, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Human immunodeficiency virus 1 infection, PD-L1 expression and PD-1 checkpoint pathway in cancer, Lipid and atherosclerosis Cyclosporine 💬 Cyclosporine 39件: 11, 14, 19, 20, 28, 36, 40, 41, 42, 45, 46, 49, 50, 53, 56, 58, 60, 61, 62, 63, 64, 65, 67, 90, 95, 97, 107, 118, 162, 164, 222, 223, 226, 228, 234, 283, 284, 285, 302 💬
126 PTGFR 💬 3件: Calcium signaling pathway, Phospholipase D signaling pathway, Neuroactive ligand-receptor interaction Unoprostone 💬 Unoprostone 1件: 90 💬
127 PTGFR 💬 3件: Calcium signaling pathway, Phospholipase D signaling pathway, Neuroactive ligand-receptor interaction Isopropyl unoprostone 💬 Unoprostone 1件: 90 💬
128 RARA 💬 5件: Th17 cell differentiation, Estrogen signaling pathway, Pathways in cancer, Transcriptional misregulation in cancer, Acute myeloid leukemia Vitamin A 💬 Vitamin A 4件: 13, 53, 90, 97 💬
129 RARB 💬 4件: Pathways in cancer, Small cell lung cancer, Non-small cell lung cancer, Gastric cancer Vitamin A 💬 Vitamin A 4件: 13, 53, 90, 97 💬
130 TNF 💬 66件: MAPK signaling pathway, Cytokine-cytokine receptor interaction, Viral protein interaction with cytokine and cytokine receptor, NF-kappa B signaling pathway, Sphingolipid signaling pathway, mTOR signaling pathway, Apoptosis, Necroptosis, TGF-beta signaling pathway, Osteoclast differentiation, Antigen processing and presentation, Toll-like receptor signaling pathway, NOD-like receptor signaling pathway, RIG-I-like receptor signaling pathway, C-type lectin receptor signaling pathway, Hematopoietic cell lineage, Natural killer cell mediated cytotoxicity, IL-17 signaling pathway, T cell receptor signaling pathway, Fc epsilon RI signaling pathway, TNF signaling pathway, Adipocytokine signaling pathway, Type II diabetes mellitus, Insulin resistance, Non-alcoholic fatty liver disease, AGE-RAGE signaling pathway in diabetic complications, Alcoholic liver disease, Type I diabetes mellitus, Alzheimer disease, Amyotrophic lateral sclerosis, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Shigellosis, Salmonella infection, Pertussis, Legionellosis, Yersinia infection, Leishmaniasis, Chagas disease, African trypanosomiasis, Malaria, Toxoplasmosis, Amoebiasis, Tuberculosis, Hepatitis C, Hepatitis B, Human cytomegalovirus infection, Influenza A, Human papillomavirus infection, Human T-cell leukemia virus 1 infection, Herpes simplex virus 1 infection, Epstein-Barr virus infection, Human immunodeficiency virus 1 infection, Coronavirus disease, Proteoglycans in cancer, Asthma, Inflammatory bowel disease, Systemic lupus erythematosus, Rheumatoid arthritis, Allograft rejection, Graft-versus-host disease, Hypertrophic cardiomyopathy, Dilated cardiomyopathy, Lipid and atherosclerosis, Fluid shear stress and atherosclerosis Adalimumab 💬 Adalimumab 22件: 19, 37, 38, 40, 41, 46, 55, 56, 84, 90, 96, 97, 107, 151, 160, 162, 164, 222, 226, 269, 270, 271 💬
131 VEGFA 💬 24件: MAPK signaling pathway, Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, HIF-1 signaling pathway, PI3K-Akt signaling pathway, VEGF signaling pathway, Focal adhesion, Integrin signaling, Relaxin signaling pathway, AGE-RAGE signaling pathway in diabetic complications, Human cytomegalovirus infection, Human papillomavirus infection, Kaposi sarcoma-associated herpesvirus infection, Pathways in cancer, Proteoglycans in cancer, MicroRNAs in cancer, Chemical carcinogenesis - receptor activation, Chemical carcinogenesis - reactive oxygen species, Renal cell carcinoma, Pancreatic cancer, Bladder cancer, Rheumatoid arthritis, Fluid shear stress and atherosclerosis Aflibercept 💬 Aflibercept 2件: 90, 166 💬
132 VEGFB 💬 10件: MAPK signaling pathway, Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, PI3K-Akt signaling pathway, Focal adhesion, Integrin signaling, Relaxin signaling pathway, AGE-RAGE signaling pathway in diabetic complications, Pathways in cancer Aflibercept 💬 Aflibercept 2件: 90, 166 💬