Target Gene/Pathway Pathway / Gene

  

Search results

No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank 指定難病告示番号
1 ADRA2A 💬 4件: cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling Dexmedetomidine 💬 Dexmedetomidine 15件: 2, 4, 6, 21, 22, 34, 46, 70, 107, 113, 171, 212, 215, 226, 280 💬
2 ADRA2A 💬 4件: cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling Dexmedetomidine hydrochloride 💬 Dexmedetomidine 15件: 2, 4, 6, 21, 22, 34, 46, 70, 107, 113, 171, 212, 215, 226, 280 💬
3 ADRA2B 💬 4件: cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling Dexmedetomidine 💬 Dexmedetomidine 15件: 2, 4, 6, 21, 22, 34, 46, 70, 107, 113, 171, 212, 215, 226, 280 💬
4 ADRA2B 💬 4件: cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling Dexmedetomidine hydrochloride 💬 Dexmedetomidine 15件: 2, 4, 6, 21, 22, 34, 46, 70, 107, 113, 171, 212, 215, 226, 280 💬
5 ADRA2C 💬 4件: cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling Dexmedetomidine 💬 Dexmedetomidine 15件: 2, 4, 6, 21, 22, 34, 46, 70, 107, 113, 171, 212, 215, 226, 280 💬
6 ADRA2C 💬 4件: cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling Dexmedetomidine hydrochloride 💬 Dexmedetomidine 15件: 2, 4, 6, 21, 22, 34, 46, 70, 107, 113, 171, 212, 215, 226, 280 💬
7 ATP4A 💬 3件: Oxidative phosphorylation, Collecting duct acid secretion, Gastric acid secretion Esomeprazole sodium 💬 Esomeprazole 10件: 6, 13, 46, 86, 98, 107, 113, 234, 298, 299 💬
8 ATP4A 💬 3件: Oxidative phosphorylation, Collecting duct acid secretion, Gastric acid secretion Esomeprazole strontium 💬 Esomeprazole 10件: 6, 13, 46, 86, 98, 107, 113, 234, 298, 299 💬
9 ATP4A 💬 3件: Oxidative phosphorylation, Collecting duct acid secretion, Gastric acid secretion Esomeprazole 💬 Esomeprazole 10件: 6, 13, 46, 86, 98, 107, 113, 234, 298, 299 💬
10 ATP4A 💬 3件: Oxidative phosphorylation, Collecting duct acid secretion, Gastric acid secretion Esomeprazole magnesium 💬 Esomeprazole 10件: 6, 13, 46, 86, 98, 107, 113, 234, 298, 299 💬
11 ATP4A 💬 3件: Oxidative phosphorylation, Collecting duct acid secretion, Gastric acid secretion Esomeprazole magnesium dihydrate 💬 Esomeprazole 10件: 6, 13, 46, 86, 98, 107, 113, 234, 298, 299 💬
12 ATP4B 💬 3件: Oxidative phosphorylation, Collecting duct acid secretion, Gastric acid secretion Esomeprazole 💬 Esomeprazole 10件: 6, 13, 46, 86, 98, 107, 113, 234, 298, 299 💬
13 ATP4B 💬 3件: Oxidative phosphorylation, Collecting duct acid secretion, Gastric acid secretion Esomeprazole magnesium 💬 Esomeprazole 10件: 6, 13, 46, 86, 98, 107, 113, 234, 298, 299 💬
14 ATP4B 💬 3件: Oxidative phosphorylation, Collecting duct acid secretion, Gastric acid secretion Esomeprazole strontium 💬 Esomeprazole 10件: 6, 13, 46, 86, 98, 107, 113, 234, 298, 299 💬
15 ATP4B 💬 3件: Oxidative phosphorylation, Collecting duct acid secretion, Gastric acid secretion Esomeprazole sodium 💬 Esomeprazole 10件: 6, 13, 46, 86, 98, 107, 113, 234, 298, 299 💬
16 ATP4B 💬 3件: Oxidative phosphorylation, Collecting duct acid secretion, Gastric acid secretion Esomeprazole magnesium dihydrate 💬 Esomeprazole 10件: 6, 13, 46, 86, 98, 107, 113, 234, 298, 299 💬
17 CD80 💬 12件: Virion - Adenovirus, Cell adhesion molecule (CAM) interaction, IgSF CAM signaling, Toll-like receptor signaling pathway, Intestinal immune network for IgA production, Type I diabetes mellitus, Autoimmune thyroid disease, Systemic lupus erythematosus, Rheumatoid arthritis, Allograft rejection, Graft-versus-host disease, Viral myocarditis Abatacept 💬 Abatacept 28件: 2, 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 223, 271, 284, 285, 300 💬
18 CD86 💬 14件: Virion - Adenovirus, Cell adhesion molecule (CAM) interaction, IgSF CAM signaling, Toll-like receptor signaling pathway, Intestinal immune network for IgA production, Type I diabetes mellitus, Kaposi sarcoma-associated herpesvirus infection, Transcriptional misregulation in cancer, Autoimmune thyroid disease, Systemic lupus erythematosus, Rheumatoid arthritis, Allograft rejection, Graft-versus-host disease, Viral myocarditis Abatacept 💬 Abatacept 28件: 2, 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 223, 271, 284, 285, 300 💬
19 DHFR 💬 3件: One carbon pool by folate, Folate biosynthesis, Folate transport and metabolism Methotrexate 💬 Methotrexate 41件: 11, 13, 14, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 54, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 223, 240, 256, 270, 271, 284, 285, 286, 326, 331 💬
20 DHFR 💬 3件: One carbon pool by folate, Folate biosynthesis, Folate transport and metabolism Methotrexate sodium 💬 Methotrexate 41件: 11, 13, 14, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 54, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 223, 240, 256, 270, 271, 284, 285, 286, 326, 331 💬
21 DHFR2 💬 3件: One carbon pool by folate, Folate biosynthesis, Folate transport and metabolism Methotrexate sodium 💬 Methotrexate 41件: 11, 13, 14, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 54, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 223, 240, 256, 270, 271, 284, 285, 286, 326, 331 💬
22 DHFR2 💬 3件: One carbon pool by folate, Folate biosynthesis, Folate transport and metabolism Methotrexate 💬 Methotrexate 41件: 11, 13, 14, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 54, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 223, 240, 256, 270, 271, 284, 285, 286, 326, 331 💬
23 DHODH 💬 1件: Pyrimidine metabolism Leflunomide 💬 Leflunomide 14件: 11, 40, 46, 49, 53, 54, 66, 107, 162, 223, 224, 270, 271, 300 💬
24 FDPS 💬 3件: Terpenoid backbone biosynthesis, Influenza A, Human T-cell leukemia virus 1 infection Risedronic acid 💬 Risedronic acid 7件: 46, 50, 93, 95, 107, 113, 274 💬
25 FDPS 💬 3件: Terpenoid backbone biosynthesis, Influenza A, Human T-cell leukemia virus 1 infection Risedronate sodium 💬 Risedronic acid 7件: 46, 50, 93, 95, 107, 113, 274 💬
26 FDPS 💬 3件: Terpenoid backbone biosynthesis, Influenza A, Human T-cell leukemia virus 1 infection Risedronate sodium monohydrate 💬 Risedronic acid 7件: 46, 50, 93, 95, 107, 113, 274 💬
27 HDAC1 💬 18件: ATP-dependent chromatin remodeling, Polycomb repressive complex, Cell cycle, Longevity regulating pathway - multiple species, Notch signaling pathway, TGF-beta signaling pathway, Neutrophil extracellular trap formation, Thyroid hormone signaling pathway, Huntington disease, Amphetamine addiction, Alcoholism, Human papillomavirus infection, Epstein-Barr virus infection, Pathways in cancer, Transcriptional misregulation in cancer, Viral carcinogenesis, MicroRNAs in cancer, Chronic myeloid leukemia Givinostat 💬 Givinostat 2件: 107, 113 💬
28 HDAC10 💬 3件: Neutrophil extracellular trap formation, Alcoholism, Viral carcinogenesis Givinostat 💬 Givinostat 2件: 107, 113 💬
29 HDAC11 💬 3件: Neutrophil extracellular trap formation, Alcoholism, Viral carcinogenesis Givinostat 💬 Givinostat 2件: 107, 113 💬
30 HDAC2 💬 18件: ATP-dependent chromatin remodeling, Polycomb repressive complex, Cell cycle, Longevity regulating pathway - multiple species, Notch signaling pathway, TGF-beta signaling pathway, Neutrophil extracellular trap formation, Thyroid hormone signaling pathway, Huntington disease, Amphetamine addiction, Alcoholism, Human papillomavirus infection, Epstein-Barr virus infection, Pathways in cancer, Transcriptional misregulation in cancer, Viral carcinogenesis, MicroRNAs in cancer, Chronic myeloid leukemia Givinostat 💬 Givinostat 2件: 107, 113 💬
31 HDAC3 💬 4件: Neutrophil extracellular trap formation, Thyroid hormone signaling pathway, Alcoholism, Viral carcinogenesis Givinostat 💬 Givinostat 2件: 107, 113 💬
32 HDAC4 💬 5件: Apelin signaling pathway, Neutrophil extracellular trap formation, Alcoholism, Viral carcinogenesis, MicroRNAs in cancer Givinostat 💬 Givinostat 2件: 107, 113 💬
33 HDAC5 💬 5件: Apelin signaling pathway, Neutrophil extracellular trap formation, Alcoholism, Viral carcinogenesis, MicroRNAs in cancer Givinostat 💬 Givinostat 2件: 107, 113 💬
34 HDAC6 💬 4件: Neutrophil extracellular trap formation, Amyotrophic lateral sclerosis, Alcoholism, Viral carcinogenesis Givinostat 💬 Givinostat 2件: 107, 113 💬
35 HDAC7 💬 3件: Neutrophil extracellular trap formation, Alcoholism, Viral carcinogenesis Givinostat 💬 Givinostat 2件: 107, 113 💬
36 HDAC8 💬 4件: Cell cycle, Neutrophil extracellular trap formation, Alcoholism, Viral carcinogenesis Givinostat 💬 Givinostat 2件: 107, 113 💬
37 HDAC9 💬 3件: Neutrophil extracellular trap formation, Alcoholism, Viral carcinogenesis Givinostat 💬 Givinostat 2件: 107, 113 💬
38 HRH2 💬 4件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Gastric acid secretion Famotidine 💬 Famotidine 7件: 6, 46, 86, 98, 107, 145, 300 💬
39 HTR3A 💬 3件: Neuroactive ligand signaling, Serotonergic synapse, Taste transduction Ondansetron hydrochloride hydrate 💬 Ondansetron 5件: 6, 97, 98, 107, 231 💬
40 HTR3A 💬 3件: Neuroactive ligand signaling, Serotonergic synapse, Taste transduction Ondansetron 💬 Ondansetron 5件: 6, 97, 98, 107, 231 💬
41 HTR3B 💬 3件: Neuroactive ligand signaling, Serotonergic synapse, Taste transduction Ondansetron 💬 Ondansetron 5件: 6, 97, 98, 107, 231 💬
42 HTR3B 💬 3件: Neuroactive ligand signaling, Serotonergic synapse, Taste transduction Ondansetron hydrochloride hydrate 💬 Ondansetron 5件: 6, 97, 98, 107, 231 💬
43 HTR3C 💬 3件: Neuroactive ligand signaling, Serotonergic synapse, Taste transduction Ondansetron hydrochloride hydrate 💬 Ondansetron 5件: 6, 97, 98, 107, 231 💬
44 HTR3C 💬 3件: Neuroactive ligand signaling, Serotonergic synapse, Taste transduction Ondansetron 💬 Ondansetron 5件: 6, 97, 98, 107, 231 💬
45 HTR3D 💬 3件: Neuroactive ligand signaling, Serotonergic synapse, Taste transduction Ondansetron 💬 Ondansetron 5件: 6, 97, 98, 107, 231 💬
46 HTR3D 💬 3件: Neuroactive ligand signaling, Serotonergic synapse, Taste transduction Ondansetron hydrochloride hydrate 💬 Ondansetron 5件: 6, 97, 98, 107, 231 💬
47 HTR3E 💬 3件: Neuroactive ligand signaling, Serotonergic synapse, Taste transduction Ondansetron 💬 Ondansetron 5件: 6, 97, 98, 107, 231 💬
48 HTR3E 💬 3件: Neuroactive ligand signaling, Serotonergic synapse, Taste transduction Ondansetron hydrochloride hydrate 💬 Ondansetron 5件: 6, 97, 98, 107, 231 💬
49 IFNG 💬 32件: Proteasome, Cytokine-cytokine receptor interaction, HIF-1 signaling pathway, Necroptosis, TGF-beta signaling pathway, Osteoclast differentiation, Antigen processing and presentation, JAK-STAT signaling pathway, Natural killer cell mediated cytotoxicity, IL-17 signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Type I diabetes mellitus, Leishmaniasis, Chagas disease, African trypanosomiasis, Malaria, Toxoplasmosis, Amoebiasis, Tuberculosis, Hepatitis C, Influenza A, Herpes simplex virus 1 infection, Pathways in cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer, Inflammatory bowel disease, Systemic lupus erythematosus, Rheumatoid arthritis, Allograft rejection, Graft-versus-host disease, Fluid shear stress and atherosclerosis Emapalumab 💬 Emapalumab 6件: 49, 50, 54, 60, 65, 107 💬
50 IL17A 💬 6件: Cytokine-cytokine receptor interaction, IL-17 signaling pathway, Th17 cell differentiation, Alcoholic liver disease, Inflammatory bowel disease, Rheumatoid arthritis Ixekizumab 💬 Ixekizumab 8件: 36, 37, 46, 107, 160, 162, 269, 271 💬
51 IL17A 💬 6件: Cytokine-cytokine receptor interaction, IL-17 signaling pathway, Th17 cell differentiation, Alcoholic liver disease, Inflammatory bowel disease, Rheumatoid arthritis Bimekizumab 💬 Bimekizumab 5件: 37, 46, 97, 107, 271 💬
52 IL17A 💬 6件: Cytokine-cytokine receptor interaction, IL-17 signaling pathway, Th17 cell differentiation, Alcoholic liver disease, Inflammatory bowel disease, Rheumatoid arthritis Secukinumab 💬 Secukinumab 9件: 13, 37, 40, 41, 46, 107, 160, 269, 271 💬
53 IL17F 💬 4件: Cytokine-cytokine receptor interaction, IL-17 signaling pathway, Th17 cell differentiation, Inflammatory bowel disease Bimekizumab 💬 Bimekizumab 5件: 37, 46, 97, 107, 271 💬
54 IL1A 💬 21件: MAPK signaling pathway, Cytokine-cytokine receptor interaction, Necroptosis, Cellular senescence, Osteoclast differentiation, Hematopoietic cell lineage, Non-alcoholic fatty liver disease, AGE-RAGE signaling pathway in diabetic complications, Type I diabetes mellitus, Alzheimer disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Pertussis, Leishmaniasis, Tuberculosis, Measles, Influenza A, Inflammatory bowel disease, Rheumatoid arthritis, Graft-versus-host disease, Fluid shear stress and atherosclerosis Rilonacept 💬 Rilonacept 5件: 51, 84, 106, 107, 266 💬
55 IL1B 💬 43件: MAPK signaling pathway, Cytokine-cytokine receptor interaction, NF-kappa B signaling pathway, Necroptosis, Osteoclast differentiation, Toll-like receptor signaling pathway, NOD-like receptor signaling pathway, Cytosolic DNA-sensing pathway, C-type lectin receptor signaling pathway, Hematopoietic cell lineage, IL-17 signaling pathway, Th17 cell differentiation, TNF signaling pathway, Inflammatory mediator regulation of TRP channels, Non-alcoholic fatty liver disease, AGE-RAGE signaling pathway in diabetic complications, Alcoholic liver disease, Type I diabetes mellitus, Alzheimer disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Shigellosis, Salmonella infection, Pertussis, Legionellosis, Yersinia infection, Leishmaniasis, Chagas disease, African trypanosomiasis, Malaria, Amoebiasis, Tuberculosis, Measles, Human cytomegalovirus infection, Influenza A, Herpes simplex virus 1 infection, Coronavirus disease, Inflammatory bowel disease, Rheumatoid arthritis, Graft-versus-host disease, Lipid and atherosclerosis, Fluid shear stress and atherosclerosis Rilonacept 💬 Rilonacept 5件: 51, 84, 106, 107, 266 💬
56 IL1B 💬 43件: MAPK signaling pathway, Cytokine-cytokine receptor interaction, NF-kappa B signaling pathway, Necroptosis, Osteoclast differentiation, Toll-like receptor signaling pathway, NOD-like receptor signaling pathway, Cytosolic DNA-sensing pathway, C-type lectin receptor signaling pathway, Hematopoietic cell lineage, IL-17 signaling pathway, Th17 cell differentiation, TNF signaling pathway, Inflammatory mediator regulation of TRP channels, Non-alcoholic fatty liver disease, AGE-RAGE signaling pathway in diabetic complications, Alcoholic liver disease, Type I diabetes mellitus, Alzheimer disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Shigellosis, Salmonella infection, Pertussis, Legionellosis, Yersinia infection, Leishmaniasis, Chagas disease, African trypanosomiasis, Malaria, Amoebiasis, Tuberculosis, Measles, Human cytomegalovirus infection, Influenza A, Herpes simplex virus 1 infection, Coronavirus disease, Inflammatory bowel disease, Rheumatoid arthritis, Graft-versus-host disease, Lipid and atherosclerosis, Fluid shear stress and atherosclerosis Canakinumab 💬 Canakinumab 11件: 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
57 IL1R1 💬 13件: MAPK signaling pathway, Cytokine-cytokine receptor interaction, NF-kappa B signaling pathway, Osteoclast differentiation, Hematopoietic cell lineage, Th17 cell differentiation, Inflammatory mediator regulation of TRP channels, Pathogenic Escherichia coli infection, Shigellosis, Amoebiasis, Human cytomegalovirus infection, Human T-cell leukemia virus 1 infection, Fluid shear stress and atherosclerosis Anakinra 💬 Anakinra 22件: 2, 13, 15, 19, 28, 37, 41, 46, 49, 50, 54, 56, 57, 84, 86, 97, 106, 107, 149, 153, 266, 299 💬
58 IL1R2 💬 7件: Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, Amoebiasis, Human T-cell leukemia virus 1 infection, Transcriptional misregulation in cancer, Prostate cancer, Fluid shear stress and atherosclerosis Anakinra 💬 Anakinra 22件: 2, 13, 15, 19, 28, 37, 41, 46, 49, 50, 54, 56, 57, 84, 86, 97, 106, 107, 149, 153, 266, 299 💬
59 IL2RA 💬 11件: Cytokine-cytokine receptor interaction, Viral protein interaction with cytokine and cytokine receptor, Endocytosis, PI3K-Akt signaling pathway, JAK-STAT signaling pathway, Hematopoietic cell lineage, Th1 and Th2 cell differentiation, Th17 cell differentiation, Measles, Human T-cell leukemia virus 1 infection, Pathways in cancer Daclizumab 💬 Daclizumab 10件: 13, 26, 56, 60, 63, 65, 97, 107, 283, 284 💬
60 IL6R 💬 11件: Cytokine-cytokine receptor interaction, Viral protein interaction with cytokine and cytokine receptor, HIF-1 signaling pathway, PI3K-Akt signaling pathway, JAK-STAT signaling pathway, Hematopoietic cell lineage, Th17 cell differentiation, Non-alcoholic fatty liver disease, Human cytomegalovirus infection, Coronavirus disease, Pathways in cancer Sarilumab 💬 Sarilumab 5件: 41, 46, 84, 107, 271 💬
61 IL6R 💬 11件: Cytokine-cytokine receptor interaction, Viral protein interaction with cytokine and cytokine receptor, HIF-1 signaling pathway, PI3K-Akt signaling pathway, JAK-STAT signaling pathway, Hematopoietic cell lineage, Th17 cell differentiation, Non-alcoholic fatty liver disease, Human cytomegalovirus infection, Coronavirus disease, Pathways in cancer Tocilizumab 💬 Tocilizumab 26件: 2, 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 65, 86, 107, 149, 153, 223, 266, 271, 298, 331 💬
62 JAK1 💬 27件: PI3K-Akt signaling pathway, Necroptosis, Osteoclast differentiation, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, NOD-like receptor signaling pathway, JAK-STAT signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Leishmaniasis, Toxoplasmosis, Tuberculosis, Hepatitis C, Hepatitis B, Measles, Human cytomegalovirus infection, Influenza A, Human papillomavirus infection, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Herpes simplex virus 1 infection, Epstein-Barr virus infection, Coronavirus disease, Pathways in cancer, Viral carcinogenesis, Pancreatic cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer Baricitinib 💬 Baricitinib 24件: 2, 13, 40, 41, 46, 49, 50, 51, 53, 54, 56, 63, 65, 84, 93, 107, 135, 162, 265, 268, 269, 300, 325, 345 💬
63 JAK1 💬 27件: PI3K-Akt signaling pathway, Necroptosis, Osteoclast differentiation, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, NOD-like receptor signaling pathway, JAK-STAT signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Leishmaniasis, Toxoplasmosis, Tuberculosis, Hepatitis C, Hepatitis B, Measles, Human cytomegalovirus infection, Influenza A, Human papillomavirus infection, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Herpes simplex virus 1 infection, Epstein-Barr virus infection, Coronavirus disease, Pathways in cancer, Viral carcinogenesis, Pancreatic cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer Upadacitinib 💬 Upadacitinib 12件: 40, 41, 46, 49, 53, 55, 63, 96, 97, 98, 107, 271 💬
64 JAK1 💬 27件: PI3K-Akt signaling pathway, Necroptosis, Osteoclast differentiation, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, NOD-like receptor signaling pathway, JAK-STAT signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Leishmaniasis, Toxoplasmosis, Tuberculosis, Hepatitis C, Hepatitis B, Measles, Human cytomegalovirus infection, Influenza A, Human papillomavirus infection, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Herpes simplex virus 1 infection, Epstein-Barr virus infection, Coronavirus disease, Pathways in cancer, Viral carcinogenesis, Pancreatic cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer Upadacitinib tartrate 💬 Upadacitinib 12件: 40, 41, 46, 49, 53, 55, 63, 96, 97, 98, 107, 271 💬
65 JAK1 💬 27件: PI3K-Akt signaling pathway, Necroptosis, Osteoclast differentiation, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, NOD-like receptor signaling pathway, JAK-STAT signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Leishmaniasis, Toxoplasmosis, Tuberculosis, Hepatitis C, Hepatitis B, Measles, Human cytomegalovirus infection, Influenza A, Human papillomavirus infection, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Herpes simplex virus 1 infection, Epstein-Barr virus infection, Coronavirus disease, Pathways in cancer, Viral carcinogenesis, Pancreatic cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer Filgotinib maleate 💬 Filgotinib 10件: 46, 53, 56, 96, 97, 107, 222, 271, 300, 331 💬
66 JAK1 💬 27件: PI3K-Akt signaling pathway, Necroptosis, Osteoclast differentiation, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, NOD-like receptor signaling pathway, JAK-STAT signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Leishmaniasis, Toxoplasmosis, Tuberculosis, Hepatitis C, Hepatitis B, Measles, Human cytomegalovirus infection, Influenza A, Human papillomavirus infection, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Herpes simplex virus 1 infection, Epstein-Barr virus infection, Coronavirus disease, Pathways in cancer, Viral carcinogenesis, Pancreatic cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer Tofacitinib citrate 💬 Tofacitinib 23件: 2, 11, 35, 38, 39, 40, 44, 46, 49, 50, 51, 53, 56, 65, 66, 84, 96, 97, 107, 110, 162, 271, 300 💬
67 JAK1 💬 27件: PI3K-Akt signaling pathway, Necroptosis, Osteoclast differentiation, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, NOD-like receptor signaling pathway, JAK-STAT signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Leishmaniasis, Toxoplasmosis, Tuberculosis, Hepatitis C, Hepatitis B, Measles, Human cytomegalovirus infection, Influenza A, Human papillomavirus infection, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Herpes simplex virus 1 infection, Epstein-Barr virus infection, Coronavirus disease, Pathways in cancer, Viral carcinogenesis, Pancreatic cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer Tofacitinib 💬 Tofacitinib 23件: 2, 11, 35, 38, 39, 40, 44, 46, 49, 50, 51, 53, 56, 65, 66, 84, 96, 97, 107, 110, 162, 271, 300 💬
68 JAK1 💬 27件: PI3K-Akt signaling pathway, Necroptosis, Osteoclast differentiation, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, NOD-like receptor signaling pathway, JAK-STAT signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Leishmaniasis, Toxoplasmosis, Tuberculosis, Hepatitis C, Hepatitis B, Measles, Human cytomegalovirus infection, Influenza A, Human papillomavirus infection, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Herpes simplex virus 1 infection, Epstein-Barr virus infection, Coronavirus disease, Pathways in cancer, Viral carcinogenesis, Pancreatic cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer Filgotinib 💬 Filgotinib 10件: 46, 53, 56, 96, 97, 107, 222, 271, 300, 331 💬
69 JAK1 💬 27件: PI3K-Akt signaling pathway, Necroptosis, Osteoclast differentiation, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, NOD-like receptor signaling pathway, JAK-STAT signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Leishmaniasis, Toxoplasmosis, Tuberculosis, Hepatitis C, Hepatitis B, Measles, Human cytomegalovirus infection, Influenza A, Human papillomavirus infection, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Herpes simplex virus 1 infection, Epstein-Barr virus infection, Coronavirus disease, Pathways in cancer, Viral carcinogenesis, Pancreatic cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer Upadacitinib hydrate 💬 Upadacitinib 12件: 40, 41, 46, 49, 53, 55, 63, 96, 97, 98, 107, 271 💬
70 JAK2 💬 25件: Chemokine signaling pathway, Hormone signaling, Efferocytosis, PI3K-Akt signaling pathway, Necroptosis, Signaling pathways regulating pluripotency of stem cells, JAK-STAT signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Cholinergic synapse, Prolactin signaling pathway, Adipocytokine signaling pathway, AGE-RAGE signaling pathway in diabetic complications, Growth hormone synthesis, secretion and action, Leishmaniasis, Toxoplasmosis, Tuberculosis, Hepatitis B, Influenza A, Kaposi sarcoma-associated herpesvirus infection, Herpes simplex virus 1 infection, Pathways in cancer, Chemical carcinogenesis - receptor activation, PD-L1 expression and PD-1 checkpoint pathway in cancer, Lipid and atherosclerosis Tofacitinib citrate 💬 Tofacitinib 23件: 2, 11, 35, 38, 39, 40, 44, 46, 49, 50, 51, 53, 56, 65, 66, 84, 96, 97, 107, 110, 162, 271, 300 💬
71 JAK2 💬 25件: Chemokine signaling pathway, Hormone signaling, Efferocytosis, PI3K-Akt signaling pathway, Necroptosis, Signaling pathways regulating pluripotency of stem cells, JAK-STAT signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Cholinergic synapse, Prolactin signaling pathway, Adipocytokine signaling pathway, AGE-RAGE signaling pathway in diabetic complications, Growth hormone synthesis, secretion and action, Leishmaniasis, Toxoplasmosis, Tuberculosis, Hepatitis B, Influenza A, Kaposi sarcoma-associated herpesvirus infection, Herpes simplex virus 1 infection, Pathways in cancer, Chemical carcinogenesis - receptor activation, PD-L1 expression and PD-1 checkpoint pathway in cancer, Lipid and atherosclerosis Filgotinib maleate 💬 Filgotinib 10件: 46, 53, 56, 96, 97, 107, 222, 271, 300, 331 💬
72 JAK2 💬 25件: Chemokine signaling pathway, Hormone signaling, Efferocytosis, PI3K-Akt signaling pathway, Necroptosis, Signaling pathways regulating pluripotency of stem cells, JAK-STAT signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Cholinergic synapse, Prolactin signaling pathway, Adipocytokine signaling pathway, AGE-RAGE signaling pathway in diabetic complications, Growth hormone synthesis, secretion and action, Leishmaniasis, Toxoplasmosis, Tuberculosis, Hepatitis B, Influenza A, Kaposi sarcoma-associated herpesvirus infection, Herpes simplex virus 1 infection, Pathways in cancer, Chemical carcinogenesis - receptor activation, PD-L1 expression and PD-1 checkpoint pathway in cancer, Lipid and atherosclerosis Baricitinib 💬 Baricitinib 24件: 2, 13, 40, 41, 46, 49, 50, 51, 53, 54, 56, 63, 65, 84, 93, 107, 135, 162, 265, 268, 269, 300, 325, 345 💬
73 JAK2 💬 25件: Chemokine signaling pathway, Hormone signaling, Efferocytosis, PI3K-Akt signaling pathway, Necroptosis, Signaling pathways regulating pluripotency of stem cells, JAK-STAT signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Cholinergic synapse, Prolactin signaling pathway, Adipocytokine signaling pathway, AGE-RAGE signaling pathway in diabetic complications, Growth hormone synthesis, secretion and action, Leishmaniasis, Toxoplasmosis, Tuberculosis, Hepatitis B, Influenza A, Kaposi sarcoma-associated herpesvirus infection, Herpes simplex virus 1 infection, Pathways in cancer, Chemical carcinogenesis - receptor activation, PD-L1 expression and PD-1 checkpoint pathway in cancer, Lipid and atherosclerosis Tofacitinib 💬 Tofacitinib 23件: 2, 11, 35, 38, 39, 40, 44, 46, 49, 50, 51, 53, 56, 65, 66, 84, 96, 97, 107, 110, 162, 271, 300 💬
74 JAK3 💬 15件: Chemokine signaling pathway, PI3K-Akt signaling pathway, Necroptosis, Signaling pathways regulating pluripotency of stem cells, JAK-STAT signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Hepatitis B, Measles, Human T-cell leukemia virus 1 infection, Epstein-Barr virus infection, Pathways in cancer, Viral carcinogenesis, Non-small cell lung cancer, Primary immunodeficiency Tofacitinib citrate 💬 Tofacitinib 23件: 2, 11, 35, 38, 39, 40, 44, 46, 49, 50, 51, 53, 56, 65, 66, 84, 96, 97, 107, 110, 162, 271, 300 💬
75 JAK3 💬 15件: Chemokine signaling pathway, PI3K-Akt signaling pathway, Necroptosis, Signaling pathways regulating pluripotency of stem cells, JAK-STAT signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Hepatitis B, Measles, Human T-cell leukemia virus 1 infection, Epstein-Barr virus infection, Pathways in cancer, Viral carcinogenesis, Non-small cell lung cancer, Primary immunodeficiency Filgotinib maleate 💬 Filgotinib 10件: 46, 53, 56, 96, 97, 107, 222, 271, 300, 331 💬
76 JAK3 💬 15件: Chemokine signaling pathway, PI3K-Akt signaling pathway, Necroptosis, Signaling pathways regulating pluripotency of stem cells, JAK-STAT signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Hepatitis B, Measles, Human T-cell leukemia virus 1 infection, Epstein-Barr virus infection, Pathways in cancer, Viral carcinogenesis, Non-small cell lung cancer, Primary immunodeficiency Tofacitinib 💬 Tofacitinib 23件: 2, 11, 35, 38, 39, 40, 44, 46, 49, 50, 51, 53, 56, 65, 66, 84, 96, 97, 107, 110, 162, 271, 300 💬
77 LTA 💬 7件: Cytokine-cytokine receptor interaction, Viral protein interaction with cytokine and cytokine receptor, NF-kappa B signaling pathway, TNF signaling pathway, Type I diabetes mellitus, Human T-cell leukemia virus 1 infection, Herpes simplex virus 1 infection Etanercept 💬 Etanercept 16件: 15, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
78 NR3C1 💬 1件: Neuroactive ligand-receptor interaction Triamcinolone acetonide 💬 Triamcinolone 11件: 35, 46, 53, 56, 70, 90, 96, 107, 162, 226, 298 💬
79 NR3C1 💬 1件: Neuroactive ligand-receptor interaction Triamcinolone hexacetonide 💬 Triamcinolone 11件: 35, 46, 53, 56, 70, 90, 96, 107, 162, 226, 298 💬
80 NR3C1 💬 1件: Neuroactive ligand-receptor interaction Triamcinolone 💬 Triamcinolone 11件: 35, 46, 53, 56, 70, 90, 96, 107, 162, 226, 298 💬
81 NR3C1 💬 1件: Neuroactive ligand-receptor interaction Prednisolone 💬 Prednisolone 48件: 3, 11, 13, 14, 18, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 54, 56, 57, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 111, 113, 145, 162, 222, 223, 251, 269, 271, 296, 299, 300 💬
82 NR3C1 💬 1件: Neuroactive ligand-receptor interaction Triamcinolone diacetate 💬 Triamcinolone 11件: 35, 46, 53, 56, 70, 90, 96, 107, 162, 226, 298 💬
83 PDE4A 💬 4件: Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Apremilast 💬 Apremilast 8件: 36, 46, 50, 56, 97, 107, 162, 271 💬
84 PDE4B 💬 4件: Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Apremilast 💬 Apremilast 8件: 36, 46, 50, 56, 97, 107, 162, 271 💬
85 PDE4C 💬 4件: Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Apremilast 💬 Apremilast 8件: 36, 46, 50, 56, 97, 107, 162, 271 💬
86 PDE4D 💬 4件: Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Apremilast 💬 Apremilast 8件: 36, 46, 50, 56, 97, 107, 162, 271 💬
87 PPP3CA 💬 33件: MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, Oocyte meiosis, Cellular senescence, Wnt signaling pathway, Axon guidance, VEGF signaling pathway, Osteoclast differentiation, C-type lectin receptor signaling pathway, Natural killer cell mediated cytotoxicity, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, B cell receptor signaling pathway, Long-term potentiation, Glutamatergic synapse, Dopaminergic synapse, Oxytocin signaling pathway, Glucagon signaling pathway, Renin secretion, Alzheimer disease, Amyotrophic lateral sclerosis, Prion disease, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Tuberculosis, Human cytomegalovirus infection, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Human immunodeficiency virus 1 infection, PD-L1 expression and PD-1 checkpoint pathway in cancer, Lipid and atherosclerosis Cyclosporine 💬 Cyclosporine 39件: 11, 14, 19, 20, 28, 36, 40, 41, 42, 45, 46, 49, 50, 53, 56, 58, 60, 61, 62, 63, 64, 65, 67, 90, 95, 97, 107, 118, 162, 164, 222, 223, 226, 228, 234, 283, 284, 285, 302 💬
88 PPP3CB 💬 33件: MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, Oocyte meiosis, Cellular senescence, Wnt signaling pathway, Axon guidance, VEGF signaling pathway, Osteoclast differentiation, C-type lectin receptor signaling pathway, Natural killer cell mediated cytotoxicity, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, B cell receptor signaling pathway, Long-term potentiation, Glutamatergic synapse, Dopaminergic synapse, Oxytocin signaling pathway, Glucagon signaling pathway, Renin secretion, Alzheimer disease, Amyotrophic lateral sclerosis, Prion disease, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Tuberculosis, Human cytomegalovirus infection, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Human immunodeficiency virus 1 infection, PD-L1 expression and PD-1 checkpoint pathway in cancer, Lipid and atherosclerosis Cyclosporine 💬 Cyclosporine 39件: 11, 14, 19, 20, 28, 36, 40, 41, 42, 45, 46, 49, 50, 53, 56, 58, 60, 61, 62, 63, 64, 65, 67, 90, 95, 97, 107, 118, 162, 164, 222, 223, 226, 228, 234, 283, 284, 285, 302 💬
89 PPP3CC 💬 33件: MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, Oocyte meiosis, Cellular senescence, Wnt signaling pathway, Axon guidance, VEGF signaling pathway, Osteoclast differentiation, C-type lectin receptor signaling pathway, Natural killer cell mediated cytotoxicity, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, B cell receptor signaling pathway, Long-term potentiation, Glutamatergic synapse, Dopaminergic synapse, Oxytocin signaling pathway, Glucagon signaling pathway, Renin secretion, Alzheimer disease, Amyotrophic lateral sclerosis, Prion disease, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Tuberculosis, Human cytomegalovirus infection, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Human immunodeficiency virus 1 infection, PD-L1 expression and PD-1 checkpoint pathway in cancer, Lipid and atherosclerosis Cyclosporine 💬 Cyclosporine 39件: 11, 14, 19, 20, 28, 36, 40, 41, 42, 45, 46, 49, 50, 53, 56, 58, 60, 61, 62, 63, 64, 65, 67, 90, 95, 97, 107, 118, 162, 164, 222, 223, 226, 228, 234, 283, 284, 285, 302 💬
90 PPP3R1 💬 32件: MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, Oocyte meiosis, Cellular senescence, Wnt signaling pathway, Axon guidance, VEGF signaling pathway, Osteoclast differentiation, C-type lectin receptor signaling pathway, Natural killer cell mediated cytotoxicity, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, B cell receptor signaling pathway, Long-term potentiation, Glutamatergic synapse, Oxytocin signaling pathway, Glucagon signaling pathway, Renin secretion, Alzheimer disease, Amyotrophic lateral sclerosis, Prion disease, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Tuberculosis, Human cytomegalovirus infection, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Human immunodeficiency virus 1 infection, PD-L1 expression and PD-1 checkpoint pathway in cancer, Lipid and atherosclerosis Cyclosporine 💬 Cyclosporine 39件: 11, 14, 19, 20, 28, 36, 40, 41, 42, 45, 46, 49, 50, 53, 56, 58, 60, 61, 62, 63, 64, 65, 67, 90, 95, 97, 107, 118, 162, 164, 222, 223, 226, 228, 234, 283, 284, 285, 302 💬
91 PPP3R2 💬 32件: MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, Oocyte meiosis, Cellular senescence, Wnt signaling pathway, Axon guidance, VEGF signaling pathway, Osteoclast differentiation, C-type lectin receptor signaling pathway, Natural killer cell mediated cytotoxicity, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, B cell receptor signaling pathway, Long-term potentiation, Glutamatergic synapse, Oxytocin signaling pathway, Glucagon signaling pathway, Renin secretion, Alzheimer disease, Amyotrophic lateral sclerosis, Prion disease, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Tuberculosis, Human cytomegalovirus infection, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Human immunodeficiency virus 1 infection, PD-L1 expression and PD-1 checkpoint pathway in cancer, Lipid and atherosclerosis Cyclosporine 💬 Cyclosporine 39件: 11, 14, 19, 20, 28, 36, 40, 41, 42, 45, 46, 49, 50, 53, 56, 58, 60, 61, 62, 63, 64, 65, 67, 90, 95, 97, 107, 118, 162, 164, 222, 223, 226, 228, 234, 283, 284, 285, 302 💬
92 PTGS1 💬 4件: Arachidonic acid metabolism, Platelet activation, Serotonergic synapse, Regulation of lipolysis in adipocytes Naproxen sodium 💬 Naproxen 4件: 13, 46, 107, 271 💬
93 PTGS1 💬 4件: Arachidonic acid metabolism, Platelet activation, Serotonergic synapse, Regulation of lipolysis in adipocytes Ibuprofen sodium 💬 Ibuprofen 8件: 13, 46, 65, 96, 107, 113, 271, 299 💬
94 PTGS1 💬 4件: Arachidonic acid metabolism, Platelet activation, Serotonergic synapse, Regulation of lipolysis in adipocytes Naproxen 💬 Naproxen 4件: 13, 46, 107, 271 💬
95 PTGS1 💬 4件: Arachidonic acid metabolism, Platelet activation, Serotonergic synapse, Regulation of lipolysis in adipocytes Ibuprofen sodium 💬 Ibuprofen 8件: 13, 46, 65, 96, 107, 113, 271, 299 💬
96 PTGS1 💬 4件: Arachidonic acid metabolism, Platelet activation, Serotonergic synapse, Regulation of lipolysis in adipocytes Ibuprofen aluminum 💬 Ibuprofen 8件: 13, 46, 65, 96, 107, 113, 271, 299 💬
97 PTGS1 💬 4件: Arachidonic acid metabolism, Platelet activation, Serotonergic synapse, Regulation of lipolysis in adipocytes Ibuprofen lysine 💬 Ibuprofen 8件: 13, 46, 65, 96, 107, 113, 271, 299 💬
98 PTGS1 💬 4件: Arachidonic acid metabolism, Platelet activation, Serotonergic synapse, Regulation of lipolysis in adipocytes Ibuprofen 💬 Ibuprofen 8件: 13, 46, 65, 96, 107, 113, 271, 299 💬
99 PTGS2 💬 22件: Arachidonic acid metabolism, NF-kappa B signaling pathway, Efferocytosis, VEGF signaling pathway, C-type lectin receptor signaling pathway, IL-17 signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Ovarian steroidogenesis, Oxytocin signaling pathway, Regulation of lipolysis in adipocytes, Alzheimer disease, Pathways of neurodegeneration - multiple diseases, Leishmaniasis, Human cytomegalovirus infection, Human papillomavirus infection, Kaposi sarcoma-associated herpesvirus infection, Pathways in cancer, Chemical carcinogenesis - DNA adducts, MicroRNAs in cancer, Small cell lung cancer Ibuprofen 💬 Ibuprofen 8件: 13, 46, 65, 96, 107, 113, 271, 299 💬
100 PTGS2 💬 22件: Arachidonic acid metabolism, NF-kappa B signaling pathway, Efferocytosis, VEGF signaling pathway, C-type lectin receptor signaling pathway, IL-17 signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Ovarian steroidogenesis, Oxytocin signaling pathway, Regulation of lipolysis in adipocytes, Alzheimer disease, Pathways of neurodegeneration - multiple diseases, Leishmaniasis, Human cytomegalovirus infection, Human papillomavirus infection, Kaposi sarcoma-associated herpesvirus infection, Pathways in cancer, Chemical carcinogenesis - DNA adducts, MicroRNAs in cancer, Small cell lung cancer Naproxen 💬 Naproxen 4件: 13, 46, 107, 271 💬
101 PTGS2 💬 22件: Arachidonic acid metabolism, NF-kappa B signaling pathway, Efferocytosis, VEGF signaling pathway, C-type lectin receptor signaling pathway, IL-17 signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Ovarian steroidogenesis, Oxytocin signaling pathway, Regulation of lipolysis in adipocytes, Alzheimer disease, Pathways of neurodegeneration - multiple diseases, Leishmaniasis, Human cytomegalovirus infection, Human papillomavirus infection, Kaposi sarcoma-associated herpesvirus infection, Pathways in cancer, Chemical carcinogenesis - DNA adducts, MicroRNAs in cancer, Small cell lung cancer Ibuprofen sodium 💬 Ibuprofen 8件: 13, 46, 65, 96, 107, 113, 271, 299 💬
102 PTGS2 💬 22件: Arachidonic acid metabolism, NF-kappa B signaling pathway, Efferocytosis, VEGF signaling pathway, C-type lectin receptor signaling pathway, IL-17 signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Ovarian steroidogenesis, Oxytocin signaling pathway, Regulation of lipolysis in adipocytes, Alzheimer disease, Pathways of neurodegeneration - multiple diseases, Leishmaniasis, Human cytomegalovirus infection, Human papillomavirus infection, Kaposi sarcoma-associated herpesvirus infection, Pathways in cancer, Chemical carcinogenesis - DNA adducts, MicroRNAs in cancer, Small cell lung cancer Celecoxib 💬 Celecoxib 14件: 2, 3, 6, 13, 34, 46, 70, 89, 96, 97, 107, 161, 171, 271 💬
103 PTGS2 💬 22件: Arachidonic acid metabolism, NF-kappa B signaling pathway, Efferocytosis, VEGF signaling pathway, C-type lectin receptor signaling pathway, IL-17 signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Ovarian steroidogenesis, Oxytocin signaling pathway, Regulation of lipolysis in adipocytes, Alzheimer disease, Pathways of neurodegeneration - multiple diseases, Leishmaniasis, Human cytomegalovirus infection, Human papillomavirus infection, Kaposi sarcoma-associated herpesvirus infection, Pathways in cancer, Chemical carcinogenesis - DNA adducts, MicroRNAs in cancer, Small cell lung cancer Ibuprofen aluminum 💬 Ibuprofen 8件: 13, 46, 65, 96, 107, 113, 271, 299 💬
104 PTGS2 💬 22件: Arachidonic acid metabolism, NF-kappa B signaling pathway, Efferocytosis, VEGF signaling pathway, C-type lectin receptor signaling pathway, IL-17 signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Ovarian steroidogenesis, Oxytocin signaling pathway, Regulation of lipolysis in adipocytes, Alzheimer disease, Pathways of neurodegeneration - multiple diseases, Leishmaniasis, Human cytomegalovirus infection, Human papillomavirus infection, Kaposi sarcoma-associated herpesvirus infection, Pathways in cancer, Chemical carcinogenesis - DNA adducts, MicroRNAs in cancer, Small cell lung cancer Ibuprofen sodium 💬 Ibuprofen 8件: 13, 46, 65, 96, 107, 113, 271, 299 💬
105 PTGS2 💬 22件: Arachidonic acid metabolism, NF-kappa B signaling pathway, Efferocytosis, VEGF signaling pathway, C-type lectin receptor signaling pathway, IL-17 signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Ovarian steroidogenesis, Oxytocin signaling pathway, Regulation of lipolysis in adipocytes, Alzheimer disease, Pathways of neurodegeneration - multiple diseases, Leishmaniasis, Human cytomegalovirus infection, Human papillomavirus infection, Kaposi sarcoma-associated herpesvirus infection, Pathways in cancer, Chemical carcinogenesis - DNA adducts, MicroRNAs in cancer, Small cell lung cancer Ibuprofen lysine 💬 Ibuprofen 8件: 13, 46, 65, 96, 107, 113, 271, 299 💬
106 PTGS2 💬 22件: Arachidonic acid metabolism, NF-kappa B signaling pathway, Efferocytosis, VEGF signaling pathway, C-type lectin receptor signaling pathway, IL-17 signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Ovarian steroidogenesis, Oxytocin signaling pathway, Regulation of lipolysis in adipocytes, Alzheimer disease, Pathways of neurodegeneration - multiple diseases, Leishmaniasis, Human cytomegalovirus infection, Human papillomavirus infection, Kaposi sarcoma-associated herpesvirus infection, Pathways in cancer, Chemical carcinogenesis - DNA adducts, MicroRNAs in cancer, Small cell lung cancer Naproxen sodium 💬 Naproxen 4件: 13, 46, 107, 271 💬
107 RRM1 💬 4件: Purine metabolism, Pyrimidine metabolism, Glutathione metabolism, Drug metabolism - other enzymes Fludarabine phosphate 💬 Fludarabine 30件: 11, 13, 14, 16, 19, 28, 34, 35, 36, 44, 46, 49, 50, 51, 60, 61, 62, 63, 65, 85, 96, 107, 164, 222, 223, 283, 284, 285, 286, 326 💬
108 RRM1 💬 4件: Purine metabolism, Pyrimidine metabolism, Glutathione metabolism, Drug metabolism - other enzymes Fludarabine 💬 Fludarabine 30件: 11, 13, 14, 16, 19, 28, 34, 35, 36, 44, 46, 49, 50, 51, 60, 61, 62, 63, 65, 85, 96, 107, 164, 222, 223, 283, 284, 285, 286, 326 💬
109 RRM2 💬 5件: Purine metabolism, Pyrimidine metabolism, Glutathione metabolism, Drug metabolism - other enzymes, p53 signaling pathway Hydroxyurea 💬 Hydroxyurea 10件: 3, 13, 19, 20, 46, 65, 85, 86, 107, 284 💬
110 SCN1A 💬 1件: Dopaminergic synapse Lidocaine 💬 Lidocaine 14件: 6, 13, 22, 34, 46, 51, 70, 86, 107, 168, 226, 231, 256, 298 💬
111 SCN1A 💬 1件: Dopaminergic synapse Lidocaine hydrochloride monohydrate 💬 Lidocaine 14件: 6, 13, 22, 34, 46, 51, 70, 86, 107, 168, 226, 231, 256, 298 💬
112 SCN1A 💬 1件: Dopaminergic synapse Lidocaine hydrochloride 💬 Lidocaine 14件: 6, 13, 22, 34, 46, 51, 70, 86, 107, 168, 226, 231, 256, 298 💬
113 SCN2A 💬 1件: Taste transduction Lidocaine hydrochloride monohydrate 💬 Lidocaine 14件: 6, 13, 22, 34, 46, 51, 70, 86, 107, 168, 226, 231, 256, 298 💬
114 SCN2A 💬 1件: Taste transduction Lidocaine 💬 Lidocaine 14件: 6, 13, 22, 34, 46, 51, 70, 86, 107, 168, 226, 231, 256, 298 💬
115 SCN2A 💬 1件: Taste transduction Lidocaine hydrochloride 💬 Lidocaine 14件: 6, 13, 22, 34, 46, 51, 70, 86, 107, 168, 226, 231, 256, 298 💬
116 SCN3A 💬 1件: Taste transduction Lidocaine hydrochloride 💬 Lidocaine 14件: 6, 13, 22, 34, 46, 51, 70, 86, 107, 168, 226, 231, 256, 298 💬
117 SCN3A 💬 1件: Taste transduction Lidocaine 💬 Lidocaine 14件: 6, 13, 22, 34, 46, 51, 70, 86, 107, 168, 226, 231, 256, 298 💬
118 SCN3A 💬 1件: Taste transduction Lidocaine hydrochloride monohydrate 💬 Lidocaine 14件: 6, 13, 22, 34, 46, 51, 70, 86, 107, 168, 226, 231, 256, 298 💬
119 SCN5A 💬 2件: Adrenergic signaling in cardiomyocytes, Cadherin signaling Lidocaine hydrochloride 💬 Lidocaine 14件: 6, 13, 22, 34, 46, 51, 70, 86, 107, 168, 226, 231, 256, 298 💬
120 SCN5A 💬 2件: Adrenergic signaling in cardiomyocytes, Cadherin signaling Lidocaine 💬 Lidocaine 14件: 6, 13, 22, 34, 46, 51, 70, 86, 107, 168, 226, 231, 256, 298 💬
121 SCN5A 💬 2件: Adrenergic signaling in cardiomyocytes, Cadherin signaling Lidocaine hydrochloride monohydrate 💬 Lidocaine 14件: 6, 13, 22, 34, 46, 51, 70, 86, 107, 168, 226, 231, 256, 298 💬
122 SCN8A 💬 1件: IgSF CAM signaling Lidocaine 💬 Lidocaine 14件: 6, 13, 22, 34, 46, 51, 70, 86, 107, 168, 226, 231, 256, 298 💬
123 SCN8A 💬 1件: IgSF CAM signaling Lidocaine hydrochloride monohydrate 💬 Lidocaine 14件: 6, 13, 22, 34, 46, 51, 70, 86, 107, 168, 226, 231, 256, 298 💬
124 SCN8A 💬 1件: IgSF CAM signaling Lidocaine hydrochloride 💬 Lidocaine 14件: 6, 13, 22, 34, 46, 51, 70, 86, 107, 168, 226, 231, 256, 298 💬
125 SCN9A 💬 1件: Taste transduction Lidocaine hydrochloride 💬 Lidocaine 14件: 6, 13, 22, 34, 46, 51, 70, 86, 107, 168, 226, 231, 256, 298 💬
126 SCN9A 💬 1件: Taste transduction Lidocaine 💬 Lidocaine 14件: 6, 13, 22, 34, 46, 51, 70, 86, 107, 168, 226, 231, 256, 298 💬
127 SCN9A 💬 1件: Taste transduction Lidocaine hydrochloride monohydrate 💬 Lidocaine 14件: 6, 13, 22, 34, 46, 51, 70, 86, 107, 168, 226, 231, 256, 298 💬
128 SERPINC1 💬 1件: Complement and coagulation cascades Heparin calcium 💬 Heparin 15件: 47, 48, 60, 65, 70, 79, 84, 107, 224, 226, 280, 299, 316, 317, 344 💬
129 SERPINC1 💬 1件: Complement and coagulation cascades Heparin sodium 💬 Heparin 15件: 47, 48, 60, 65, 70, 79, 84, 107, 224, 226, 280, 299, 316, 317, 344 💬
130 TNF 💬 66件: MAPK signaling pathway, Cytokine-cytokine receptor interaction, Viral protein interaction with cytokine and cytokine receptor, NF-kappa B signaling pathway, Sphingolipid signaling pathway, mTOR signaling pathway, Apoptosis, Necroptosis, TGF-beta signaling pathway, Osteoclast differentiation, Antigen processing and presentation, Toll-like receptor signaling pathway, NOD-like receptor signaling pathway, RIG-I-like receptor signaling pathway, C-type lectin receptor signaling pathway, Hematopoietic cell lineage, Natural killer cell mediated cytotoxicity, IL-17 signaling pathway, T cell receptor signaling pathway, Fc epsilon RI signaling pathway, TNF signaling pathway, Adipocytokine signaling pathway, Type II diabetes mellitus, Insulin resistance, Non-alcoholic fatty liver disease, AGE-RAGE signaling pathway in diabetic complications, Alcoholic liver disease, Type I diabetes mellitus, Alzheimer disease, Amyotrophic lateral sclerosis, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Shigellosis, Salmonella infection, Pertussis, Legionellosis, Yersinia infection, Leishmaniasis, Chagas disease, African trypanosomiasis, Malaria, Toxoplasmosis, Amoebiasis, Tuberculosis, Hepatitis C, Hepatitis B, Human cytomegalovirus infection, Influenza A, Human papillomavirus infection, Human T-cell leukemia virus 1 infection, Herpes simplex virus 1 infection, Epstein-Barr virus infection, Human immunodeficiency virus 1 infection, Coronavirus disease, Proteoglycans in cancer, Asthma, Inflammatory bowel disease, Systemic lupus erythematosus, Rheumatoid arthritis, Allograft rejection, Graft-versus-host disease, Hypertrophic cardiomyopathy, Dilated cardiomyopathy, Lipid and atherosclerosis, Fluid shear stress and atherosclerosis Etanercept 💬 Etanercept 16件: 15, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
131 TNF 💬 66件: MAPK signaling pathway, Cytokine-cytokine receptor interaction, Viral protein interaction with cytokine and cytokine receptor, NF-kappa B signaling pathway, Sphingolipid signaling pathway, mTOR signaling pathway, Apoptosis, Necroptosis, TGF-beta signaling pathway, Osteoclast differentiation, Antigen processing and presentation, Toll-like receptor signaling pathway, NOD-like receptor signaling pathway, RIG-I-like receptor signaling pathway, C-type lectin receptor signaling pathway, Hematopoietic cell lineage, Natural killer cell mediated cytotoxicity, IL-17 signaling pathway, T cell receptor signaling pathway, Fc epsilon RI signaling pathway, TNF signaling pathway, Adipocytokine signaling pathway, Type II diabetes mellitus, Insulin resistance, Non-alcoholic fatty liver disease, AGE-RAGE signaling pathway in diabetic complications, Alcoholic liver disease, Type I diabetes mellitus, Alzheimer disease, Amyotrophic lateral sclerosis, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Shigellosis, Salmonella infection, Pertussis, Legionellosis, Yersinia infection, Leishmaniasis, Chagas disease, African trypanosomiasis, Malaria, Toxoplasmosis, Amoebiasis, Tuberculosis, Hepatitis C, Hepatitis B, Human cytomegalovirus infection, Influenza A, Human papillomavirus infection, Human T-cell leukemia virus 1 infection, Herpes simplex virus 1 infection, Epstein-Barr virus infection, Human immunodeficiency virus 1 infection, Coronavirus disease, Proteoglycans in cancer, Asthma, Inflammatory bowel disease, Systemic lupus erythematosus, Rheumatoid arthritis, Allograft rejection, Graft-versus-host disease, Hypertrophic cardiomyopathy, Dilated cardiomyopathy, Lipid and atherosclerosis, Fluid shear stress and atherosclerosis Adalimumab 💬 Adalimumab 22件: 19, 37, 38, 40, 41, 46, 55, 56, 84, 90, 96, 97, 107, 151, 160, 162, 164, 222, 226, 269, 270, 271 💬
132 TNF 💬 66件: MAPK signaling pathway, Cytokine-cytokine receptor interaction, Viral protein interaction with cytokine and cytokine receptor, NF-kappa B signaling pathway, Sphingolipid signaling pathway, mTOR signaling pathway, Apoptosis, Necroptosis, TGF-beta signaling pathway, Osteoclast differentiation, Antigen processing and presentation, Toll-like receptor signaling pathway, NOD-like receptor signaling pathway, RIG-I-like receptor signaling pathway, C-type lectin receptor signaling pathway, Hematopoietic cell lineage, Natural killer cell mediated cytotoxicity, IL-17 signaling pathway, T cell receptor signaling pathway, Fc epsilon RI signaling pathway, TNF signaling pathway, Adipocytokine signaling pathway, Type II diabetes mellitus, Insulin resistance, Non-alcoholic fatty liver disease, AGE-RAGE signaling pathway in diabetic complications, Alcoholic liver disease, Type I diabetes mellitus, Alzheimer disease, Amyotrophic lateral sclerosis, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Shigellosis, Salmonella infection, Pertussis, Legionellosis, Yersinia infection, Leishmaniasis, Chagas disease, African trypanosomiasis, Malaria, Toxoplasmosis, Amoebiasis, Tuberculosis, Hepatitis C, Hepatitis B, Human cytomegalovirus infection, Influenza A, Human papillomavirus infection, Human T-cell leukemia virus 1 infection, Herpes simplex virus 1 infection, Epstein-Barr virus infection, Human immunodeficiency virus 1 infection, Coronavirus disease, Proteoglycans in cancer, Asthma, Inflammatory bowel disease, Systemic lupus erythematosus, Rheumatoid arthritis, Allograft rejection, Graft-versus-host disease, Hypertrophic cardiomyopathy, Dilated cardiomyopathy, Lipid and atherosclerosis, Fluid shear stress and atherosclerosis Infliximab 💬 Infliximab 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 95, 96, 97, 98, 107, 162, 164, 223, 269, 270, 271 💬
133 TNF 💬 66件: MAPK signaling pathway, Cytokine-cytokine receptor interaction, Viral protein interaction with cytokine and cytokine receptor, NF-kappa B signaling pathway, Sphingolipid signaling pathway, mTOR signaling pathway, Apoptosis, Necroptosis, TGF-beta signaling pathway, Osteoclast differentiation, Antigen processing and presentation, Toll-like receptor signaling pathway, NOD-like receptor signaling pathway, RIG-I-like receptor signaling pathway, C-type lectin receptor signaling pathway, Hematopoietic cell lineage, Natural killer cell mediated cytotoxicity, IL-17 signaling pathway, T cell receptor signaling pathway, Fc epsilon RI signaling pathway, TNF signaling pathway, Adipocytokine signaling pathway, Type II diabetes mellitus, Insulin resistance, Non-alcoholic fatty liver disease, AGE-RAGE signaling pathway in diabetic complications, Alcoholic liver disease, Type I diabetes mellitus, Alzheimer disease, Amyotrophic lateral sclerosis, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Shigellosis, Salmonella infection, Pertussis, Legionellosis, Yersinia infection, Leishmaniasis, Chagas disease, African trypanosomiasis, Malaria, Toxoplasmosis, Amoebiasis, Tuberculosis, Hepatitis C, Hepatitis B, Human cytomegalovirus infection, Influenza A, Human papillomavirus infection, Human T-cell leukemia virus 1 infection, Herpes simplex virus 1 infection, Epstein-Barr virus infection, Human immunodeficiency virus 1 infection, Coronavirus disease, Proteoglycans in cancer, Asthma, Inflammatory bowel disease, Systemic lupus erythematosus, Rheumatoid arthritis, Allograft rejection, Graft-versus-host disease, Hypertrophic cardiomyopathy, Dilated cardiomyopathy, Lipid and atherosclerosis, Fluid shear stress and atherosclerosis Certolizumab pegol 💬 Certolizumab pegol 10件: 37, 40, 46, 48, 49, 96, 97, 107, 226, 271 💬
134 TNF 💬 66件: MAPK signaling pathway, Cytokine-cytokine receptor interaction, Viral protein interaction with cytokine and cytokine receptor, NF-kappa B signaling pathway, Sphingolipid signaling pathway, mTOR signaling pathway, Apoptosis, Necroptosis, TGF-beta signaling pathway, Osteoclast differentiation, Antigen processing and presentation, Toll-like receptor signaling pathway, NOD-like receptor signaling pathway, RIG-I-like receptor signaling pathway, C-type lectin receptor signaling pathway, Hematopoietic cell lineage, Natural killer cell mediated cytotoxicity, IL-17 signaling pathway, T cell receptor signaling pathway, Fc epsilon RI signaling pathway, TNF signaling pathway, Adipocytokine signaling pathway, Type II diabetes mellitus, Insulin resistance, Non-alcoholic fatty liver disease, AGE-RAGE signaling pathway in diabetic complications, Alcoholic liver disease, Type I diabetes mellitus, Alzheimer disease, Amyotrophic lateral sclerosis, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Shigellosis, Salmonella infection, Pertussis, Legionellosis, Yersinia infection, Leishmaniasis, Chagas disease, African trypanosomiasis, Malaria, Toxoplasmosis, Amoebiasis, Tuberculosis, Hepatitis C, Hepatitis B, Human cytomegalovirus infection, Influenza A, Human papillomavirus infection, Human T-cell leukemia virus 1 infection, Herpes simplex virus 1 infection, Epstein-Barr virus infection, Human immunodeficiency virus 1 infection, Coronavirus disease, Proteoglycans in cancer, Asthma, Inflammatory bowel disease, Systemic lupus erythematosus, Rheumatoid arthritis, Allograft rejection, Graft-versus-host disease, Hypertrophic cardiomyopathy, Dilated cardiomyopathy, Lipid and atherosclerosis, Fluid shear stress and atherosclerosis Golimumab 💬 Golimumab 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬
135 TYK2 💬 17件: Necroptosis, Osteoclast differentiation, Toll-like receptor signaling pathway, NOD-like receptor signaling pathway, JAK-STAT signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Hepatitis C, Hepatitis B, Measles, Influenza A, Human papillomavirus infection, Kaposi sarcoma-associated herpesvirus infection, Herpes simplex virus 1 infection, Epstein-Barr virus infection, Coronavirus disease Tofacitinib 💬 Tofacitinib 23件: 2, 11, 35, 38, 39, 40, 44, 46, 49, 50, 51, 53, 56, 65, 66, 84, 96, 97, 107, 110, 162, 271, 300 💬
136 TYK2 💬 17件: Necroptosis, Osteoclast differentiation, Toll-like receptor signaling pathway, NOD-like receptor signaling pathway, JAK-STAT signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Hepatitis C, Hepatitis B, Measles, Influenza A, Human papillomavirus infection, Kaposi sarcoma-associated herpesvirus infection, Herpes simplex virus 1 infection, Epstein-Barr virus infection, Coronavirus disease Tofacitinib citrate 💬 Tofacitinib 23件: 2, 11, 35, 38, 39, 40, 44, 46, 49, 50, 51, 53, 56, 65, 66, 84, 96, 97, 107, 110, 162, 271, 300 💬
137 TYK2 💬 17件: Necroptosis, Osteoclast differentiation, Toll-like receptor signaling pathway, NOD-like receptor signaling pathway, JAK-STAT signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Hepatitis C, Hepatitis B, Measles, Influenza A, Human papillomavirus infection, Kaposi sarcoma-associated herpesvirus infection, Herpes simplex virus 1 infection, Epstein-Barr virus infection, Coronavirus disease Filgotinib maleate 💬 Filgotinib 10件: 46, 53, 56, 96, 97, 107, 222, 271, 300, 331 💬
138 VDR 💬 5件: Parathyroid hormone synthesis, secretion and action, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Tuberculosis, Chemical carcinogenesis - receptor activation Alfacalcidol 💬 Alfacalcidol 10件: 41, 46, 49, 50, 96, 107, 222, 223, 235, 238 💬